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ChEMBL ligand: CHEMBL3560390 |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium berghei [GtoPdb: 2954] | ||||||||
GtoPdb | Parasite liver stage assay | - | 6.85 | pEC50 | 140 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum [GtoPdb: 2954] | ||||||||
GtoPdb | - | - | 7.34 | pIC50 | 46 | nM | IC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum 3D7 [GtoPdb: 2954] [UniProtKB: Q8I246] | ||||||||
GtoPdb | Parasite late stage (IV–V) gametocyte assay | - | 6.18 | pEC50 | 663 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
Plasmodium falciparum phenylalanyl-tRNA synthetase alpha subunit in Plasmodium falciparum Dd2 [GtoPdb: 2954] | ||||||||
GtoPdb | Parasite growth inhibition assay | - | 8.05 | pEC50 | 9 | nM | EC50 | Nature (2016) 538: 344-349 [PMID:27602946] |
ChEMBL data shown on this page come from version 28:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]