eganelisib [Ligand Id: 9563] activity data from GtoPdb

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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
Created with Highcharts 10.3.3ValuesChart context menuphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alphapKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
Created with Highcharts 10.3.3ValuesChart context menuphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit betapKd HumanpKi HumanpIC50 HumanpEC50 Human02468Highcharts.com
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
Created with Highcharts 10.3.3ValuesChart context menuphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit deltapKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
Created with Highcharts 10.3.3ValuesChart context menuphosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gammapKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha in Human [GtoPdb: 2153] [UniProtKB: P42336]
GtoPdb - - 7.77 pKd 17 nM Kd ACS Med Chem Lett (2016) 7: 862-7 [PMID:27660692]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta in Human [GtoPdb: 2154] [UniProtKB: P42338]
GtoPdb - - 7.09 pKd 82 nM Kd ACS Med Chem Lett (2016) 7: 862-7 [PMID:27660692]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta in Human [GtoPdb: 2155] [UniProtKB: O00329]
GtoPdb - - 7.64 pKd 23 nM Kd ACS Med Chem Lett (2016) 7: 862-7 [PMID:27660692]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb - - 9.54 pKd 0.29 nM Kd ACS Med Chem Lett (2016) 7: 862-7 [PMID:27660692]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.