5H3'FPE [Ligand Id: 8748] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL2347914
  • CYP1A1 in Human [GtoPdb: 1318] [UniProtKB: P04798]
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  • CYP1A2 in Human [GtoPdb: 1319] [UniProtKB: P05177]
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  • CYP1B1 in Human [GtoPdb: 1320] [UniProtKB: Q16678]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CYP1A1 in Human [GtoPdb: 1318] [UniProtKB: P04798]
GtoPdb - - 7.37 pIC50 43 nM IC50 J Med Chem (2013) 56: 4082-92 [PMID:23600958]
CYP1A2 in Human [GtoPdb: 1319] [UniProtKB: P05177]
GtoPdb - - 6.38 pIC50 420 nM IC50 J Med Chem (2013) 56: 4082-92 [PMID:23600958]
CYP1B1 in Human [GtoPdb: 1320] [UniProtKB: Q16678]
GtoPdb - - 7.62 pIC50 24 nM IC50 J Med Chem (2013) 56: 4082-92 [PMID:23600958]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]