berzosertib [Ligand Id: 8003] activity data from GtoPdb

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  • ATM serine/threonine kinase in Human [GtoPdb: 1934] [UniProtKB: Q13315]
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  • ATR serine/threonine kinase in Human [GtoPdb: 1935] [UniProtKB: Q13535]
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  • mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345]
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  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
ATM serine/threonine kinase in Human [GtoPdb: 1934] [UniProtKB: Q13315]
GtoPdb - - 7.47 pKi 34 nM Ki Cell Death Dis (2012) 3: e441 [PMID:23222511]
ATR serine/threonine kinase in Human [GtoPdb: 1935] [UniProtKB: Q13535]
GtoPdb - - 9.7 pKi <0.2 nM Ki Cell Death Dis (2012) 3: e441 [PMID:23222511]
mechanistic target of rapamycin kinase in Human [GtoPdb: 2109] [UniProtKB: P42345]
GtoPdb - - 6 pKi >1000 nM Ki Cell Death Dis (2012) 3: e441 [PMID:23222511]
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma in Human [GtoPdb: 2156] [UniProtKB: P48736]
GtoPdb - - 6.66 pKi 220 nM Ki Cell Death Dis (2012) 3: e441 [PMID:23222511]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.