GDC-0152 [Ligand Id: 7733] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2063869 |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| X-linked inhibitor of apoptosis in Human [GtoPdb: 2790] [UniProtKB: P98170] | ||||||||
| GtoPdb | BIR3 domain of hXIAP | - | 7.55 | pKi | 28 | nM | Ki | J Med Chem (2012) 55: 4101-13 [PMID:22413863] |
| baculoviral IAP repeat containing 2 in Human [GtoPdb: 2791] [UniProtKB: Q13490] | ||||||||
| GtoPdb | BIR3 domain of hcIAP1 (BIRC2) | - | 7.77 | pKi | 17 | nM | Ki | J Med Chem (2012) 55: 4101-13 [PMID:22413863] |
| baculoviral IAP repeat containing 3 in Human [GtoPdb: 2792] [UniProtKB: Q13489] | ||||||||
| GtoPdb | BIR3 domain of hcIPA2 (BIRC3) | - | 7.37 | pKi | 43 | nM | Ki | J Med Chem (2012) 55: 4101-13 [PMID:22413863] |
| baculoviral IAP repeat containing 7 in Human [GtoPdb: 2794] [UniProtKB: Q96CA5] | ||||||||
| GtoPdb | BIR domain of hML-IAP (BIRC7) | - | 7.85 | pKi | 14 | nM | Ki | J Med Chem (2012) 55: 4101-13 [PMID:22413863] |
ChEMBL data shown on this page come from version 35:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
