ChEMBL ligand: CHEMBL1269025 (DU-176, Edoxaban, Lixiana)
coagulation factor X/Coagulation factor X in Human [ChEMBL: CHEMBL244] [GtoPdb: 2359] [UniProtKB: P00742] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
coagulation factor X/Coagulation factor X in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL244] [GtoPdb: 2359] [UniProtKB: P00742]
GtoPdb	-	-	9.25	pKi	0.56	nM	Ki	J Med Chem (2010) 53: 6243-74 [PMID:20503967]; J Thromb Haemost (2008) 6: 1542-9 [PMID:18624979]
ChEMBL	Inhibition of factor 10a	B	9.25	pKi	0.56	nM	Ki	J Med Chem (2010) 53: 6243-6274 [PMID:20503967]
ChEMBL	Inhibition of human coagulation factor 10a using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV absorption assay	B	8.47	pIC50	3.4	nM	IC50	Bioorg Med Chem Lett (2018) 28: 3813-3815 [PMID:30340898]
ChEMBL	Inhibition of human factor Xa using Z-D-Arg-Gly-Arg-pNA.2HCl as substrate preincubated for 15 mins followed by substrate addition by UV absorption analysis	B	8.47	pIC50	3.4	nM	IC50	Bioorg Med Chem (2019) 27: 1320-1326 [PMID:30792102]

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]