ChEMBL ligand: CHEMBL1472975 (Perospirona, Perospirone)
5-HT2A receptor in Rat [GtoPdb: 6] [UniProtKB: P14842] There should be some charts here, you may need to enable JavaScript!
D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416] There should be some charts here, you may need to enable JavaScript!
D3 receptor in Human [GtoPdb: 216] [UniProtKB: P35462] There should be some charts here, you may need to enable JavaScript!
D4 receptor in Human [GtoPdb: 217] [UniProtKB: P21917] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
5-HT2A receptor in Rat [GtoPdb: 6] [UniProtKB: P14842]
GtoPdb	-	-	4.74	pKi	18000	nM	Ki	Proc Natl Acad Sci USA (1975) 72: 4376-80 [PMID:1060115]
D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
GtoPdb	-	-	9.22	pKi	0.6	nM	Ki	Proc Natl Acad Sci USA (1975) 72: 4376-80 [PMID:1060115]
D3 receptor in Human [GtoPdb: 216] [UniProtKB: P35462]
GtoPdb	-	-	9.55	pKi	0.28	nM	Ki	Eur J Pharmacol (1992) 225: 331-7 [PMID:1354163]
D4 receptor in Human [GtoPdb: 217] [UniProtKB: P21917]
GtoPdb	-	-	10.05	pKi	0.09	nM	Ki	Mol Psychiatry (1998) 3: 123-34 [PMID:9577836]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]