benzquinamide [Ligand Id: 7124] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1201250 (Benzchinamide, Benzquinamide, Emete-con, NSC-108159, NSC-169193, NSC-64375, P-2647, Promecon, Quantril)
  • D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
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  • COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
D2 receptor in Human [GtoPdb: 215] [UniProtKB: P14416]
GtoPdb - - 5.4 pKi 3964 nM Ki Proc Natl Acad Sci USA (2012) 109: 11178-83 [PMID:22711801]
COX-2 in Human [GtoPdb: 1376] [UniProtKB: P35354]
GtoPdb - - 8.32 pIC50 4.8 nM IC50 National Toxicology Program: Dept of Health and Human Services.. DrugMatrix

ChEMBL data shown on this page come from version 32:

Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]