VPC03090-P [Ligand Id: 6992] activity data from GtoPdb

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  • S1P1 receptor in Human [GtoPdb: 275] [UniProtKB: P21453]
  • S1P1 receptor in Mouse [GtoPdb: 275] [UniProtKB: O08530]
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  • S1P3 receptor in Human [GtoPdb: 277] [UniProtKB: Q99500]
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  • S1P4 receptor in Human [GtoPdb: 278] [UniProtKB: O95977]
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  • S1P5 receptor in Human [GtoPdb: 279] [UniProtKB: Q9H228]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
S1P1 receptor in Human [GtoPdb: 275] [UniProtKB: P21453]
GtoPdb - - 7.68 pKi 21 nM Ki J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]
S1P1 receptor in Mouse [GtoPdb: 275] [UniProtKB: O08530]
GtoPdb - - 7.85 pKi 14 nM Ki J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]
S1P3 receptor in Human [GtoPdb: 277] [UniProtKB: Q99500]
GtoPdb - - 7.29 pKi 51 nM Ki J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]
S1P4 receptor in Human [GtoPdb: 278] [UniProtKB: O95977]
GtoPdb - - 7.76 pKd 17.3 nM Kd J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]
GtoPdb - - 7.75 pEC50 17.7 nM EC50 J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]
S1P5 receptor in Human [GtoPdb: 279] [UniProtKB: Q9H228]
GtoPdb - - 8.64 pKd 2.3 nM Kd J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]
GtoPdb - - 8.62 pEC50 2.4 nM EC50 J Pharmacol Exp Ther (2011) 338: 879-89 [PMID:21632869]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.