ChEMBL ligand: CHEMBL782 (1-butyl-3-(p-tolylsulfonyl)urea, Arkozal, Butamide, Diabetamid, Glyconon, Ipoglicone, NSC-23813, NSC-87833, Orinase, Pramidex, Rastinon, Tolbutamida, Tolbutamide, Tolbutamidum, Willbutamide)
Organic anion transporter 1/Solute carrier family 22 member 6 in Rat [ChEMBL: CHEMBL1777665] [GtoPdb: 1025] [UniProtKB: O35956] There should be some charts here, you may need to enable JavaScript!
Kir6.2 in Mouse [GtoPdb: 442] [UniProtKB: Q61743] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
Organic anion transporter 1/Solute carrier family 22 member 6 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1777665] [GtoPdb: 1025] [UniProtKB: O35956]
ChEMBL	Inhibition of rat Oat1 expressed in Xenopus oocytes	B	4.26	pKi	55500	nM	Ki	Bioorg Med Chem (2011) 19: 3320-3340 [PMID:21571536]
ChEMBL	TP_TRANSPORTER: inhibition of PAH uptake in Xenopus laevis oocytes	F	4.26	pKi	55500	nM	Ki	Eur J Pharmacol (2000) 398: 193-197 [PMID:10854830]
Kir6.2 in Mouse [GtoPdb: 442] [UniProtKB: Q61743]
GtoPdb	-	-	4.5	pIC50	-	-	-	Science (1995) 270: 1166-70 [PMID:7502040]

ChEMBL data shown on this page come from version 35:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]