compound 18 [PMID: 21927650] [Ligand Id: 6442] activity data from GtoPdb

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  • mGlu5 receptor in Human [GtoPdb: 293] [UniProtKB: P41594]
  • mGlu5 receptor in Rat [GtoPdb: 293] [UniProtKB: P31424]
Created with Highcharts 10.3.3ValuesChart context menumGlu5 receptorpKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
mGlu5 receptor in Human [GtoPdb: 293] [UniProtKB: P41594]
GtoPdb - - 7.21 pIC50 61 nM IC50 ACS Chem Neurosci (2011) 2: 471-482 [PMID:21927650]
mGlu5 receptor in Rat [GtoPdb: 293] [UniProtKB: P31424]
GtoPdb - - 6.32 pKi 477 nM Ki ACS Chem Neurosci (2011) 2: 471-482 [PMID:21927650]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.