purvalanol A [Ligand Id: 6030] activity data from GtoPdb

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  • cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941]
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  • cyclin dependent kinase 4 in Human [GtoPdb: 1976] [UniProtKB: P11802]
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  • cyclin dependent kinase 5 in Human [GtoPdb: 1977] [UniProtKB: Q00535]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
cyclin dependent kinase 2 in Human [GtoPdb: 1973] [UniProtKB: P24941]
GtoPdb CDK2/cyclin E complex used in assay - 7.46 pIC50 35 nM IC50 Science (1998) 281: 533-8 [PMID:9677190]
cyclin dependent kinase 4 in Human [GtoPdb: 1976] [UniProtKB: P11802]
GtoPdb CDK4/cyclin D1 complex used in assay - 6.07 pIC50 850 nM IC50 Science (1998) 281: 533-8 [PMID:9677190]
cyclin dependent kinase 5 in Human [GtoPdb: 1977] [UniProtKB: Q00535]
GtoPdb CDK5/p35 complex used in assay - 7.12 pIC50 75 nM IC50 Science (1998) 281: 533-8 [PMID:9677190]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.