nadolol [Ligand Id: 554] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL649 (Nadolol, SQ 11725, Solgol, Corgard, SQ-11725)
  • β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
There should be some charts here, you may need to enable JavaScript!
  • β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
There should be some charts here, you may need to enable JavaScript!
  • β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
β1-adrenoceptor in Human [GtoPdb: 28] [UniProtKB: P08588]
GtoPdb - - 6.9 pKi - - - J Pharmacol Exp Ther (1999) 290: 649-55 [PMID:10411574]
β2-adrenoceptor in Human [GtoPdb: 29] [UniProtKB: P07550]
GtoPdb - - 8.6 pKi - - - Br J Pharmacol (2005) 144: 317-22 [PMID:15655528];
J Pharmacol Exp Ther (1999) 290: 649-55 [PMID:10411574]
β3-adrenoceptor in Human [GtoPdb: 30] [UniProtKB: P13945]
GtoPdb - - 6.3 pKi - - - J Pharmacol Exp Ther (1999) 290: 649-55 [PMID:10411574]

ChEMBL data shown on this page come from version 28:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, Cibrián-Uhalte E, Davies M, Dedman N, Karlsson A, Magariños MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]