aminohippuric acid [Ligand Id: 4810] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL463 (Aminohippuric acid, Aminohippuric Acid, Aminohippuric acid, p-, NSC-13064, Paha, P-aminohippuric acid, Para-aminohippurate, Para-aminohippuric acid) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| Organic anion transporter 1/Solute carrier family 22 member 6 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641347] [GtoPdb: 1025] [UniProtKB: Q4U2R8] | ||||||||
| ChEMBL | Inhibition of human Oat1 expressed in Drosophila S2 cells | B | 5.22 | pKi | 6020 | nM | Ki | Bioorg Med Chem (2011) 19: 3320-3340 [PMID:21571536] |
| ChEMBL | TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT1-expressing S2 cells | F | 5.22 | pKi | 6020 | nM | Ki | Life Sci (2001) 69: 2123-2135 [PMID:11669456] |
| ChEMBL | TP_TRANSPORTER: inhibition of 6-Carboxyfluorescein uptake in OAT1-expressing CHO cells | F | 5.06 | pIC50 | 8800 | nM | IC50 | Anal Biochem (2000) 283: 49-55 [PMID:10929807] |
| Organic anion transporter 1/Solute carrier family 22 member 6 in Mouse (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5653] [GtoPdb: 1025] [UniProtKB: Q8VC69] | ||||||||
| ChEMBL | Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr | B | 5.03 | pKi | 9400 | nM | Ki | J Biol Chem (2007) 282: 23841-23853 [PMID:17553798] |
| ChEMBL | Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hr | B | 5.03 | pKi | 9332.54 | nM | Ki | J Biol Chem (2007) 282: 23841-23853 [PMID:17553798] |
| Organic anion transporter 3/Solute carrier family 22 member 8 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1641348] [GtoPdb: 1027] [UniProtKB: Q8TCC7] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of Ochratoxin A uptake in OAT3-expressing S2 cells | F | 4.71 | pKi | 19600 | nM | Ki | Life Sci (2001) 69: 2123-2135 [PMID:11669456] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
