TMB-8 [Ligand Id: 4323] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL258764
  • 5-HT3A in Human [GtoPdb: 379]
  • 5-HT3A in Mouse [GtoPdb: 379]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
5-HT3A in Human [GtoPdb: 379]
GtoPdb - - 4.93 pIC50 11760 nM IC50 J Pharmacol Exp Ther (1999) 290: 129-35 [PMID:10381768]
5-HT3A in Mouse [GtoPdb: 379]
GtoPdb - - 5.35 pIC50 4500 nM IC50 J Pharmacol Exp Ther (1999) 290: 129-35 [PMID:10381768];
Biol Pharm Bull (2009) 32: 861-7 [PMID:19420755]

ChEMBL data shown on this page come from version 31:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]