ChEMBL ligand: CHEMBL1213327 (CoASH, Coenzyme_a, Coenzyme A)
choline O-acetyltransferase/Choline acetylase in Human [ChEMBL: CHEMBL4039] [GtoPdb: 2480] [UniProtKB: P28329] There should be some charts here, you may need to enable JavaScript!
lysine acetyltransferase 5/Histone acetyltransferase KAT5 in Human [ChEMBL: CHEMBL5750] [GtoPdb: 2664] [UniProtKB: Q92993] There should be some charts here, you may need to enable JavaScript!
E1A binding protein p300/Histone acetyltransferase p300 in Human [ChEMBL: CHEMBL3784] [GtoPdb: 2735] [UniProtKB: Q09472] There should be some charts here, you may need to enable JavaScript!
lysine acetyltransferase 2B/Histone acetyltransferase PCAF in Human [ChEMBL: CHEMBL5500] [GtoPdb: 2737] [UniProtKB: Q92831] There should be some charts here, you may need to enable JavaScript!
N-alpha-acetyltransferase 50 in Human [ChEMBL: CHEMBL4630854] [UniProtKB: Q9GZZ1] There should be some charts here, you may need to enable JavaScript!

DB	Assay description	Assay Type	Standard value	Standard parameter	Original value	Original units	Original parameter	Reference
choline O-acetyltransferase/Choline acetylase in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4039] [GtoPdb: 2480] [UniProtKB: P28329]
ChEMBL	Inhibition of choline acetyltransferase isolated from squid head ganglia	B	4.12	pKi	75000	nM	Ki	J Med Chem (1981) 24: 1534-1537 [PMID:7310833]
lysine acetyltransferase 5/Histone acetyltransferase KAT5 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5750] [GtoPdb: 2664] [UniProtKB: Q92993]
ChEMBL	Inhibition of recombinant Tip60 (1-513) expressed in Escherichia coli BL21 (DE3) by liquid scintillation	B	4.08	pIC50	82270	nM	IC50	Bioorg Med Chem (2009) 17: 1381-1386 [PMID:19114310]
E1A binding protein p300/Histone acetyltransferase p300 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL3784] [GtoPdb: 2735] [UniProtKB: Q09472]
ChEMBL	Inhibition of recombinant p300	B	4.34	pIC50	45940	nM	IC50	Bioorg Med Chem (2009) 17: 1381-1386 [PMID:19114310]
lysine acetyltransferase 2B/Histone acetyltransferase PCAF in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL5500] [GtoPdb: 2737] [UniProtKB: Q92831]
ChEMBL	Inhibition of PCAF HAT domain (493-658) expressed in Escherichia coli BL21 (DE3)	B	4.38	pIC50	41910	nM	IC50	Bioorg Med Chem (2009) 17: 1381-1386 [PMID:19114310]
N-alpha-acetyltransferase 50 in Human (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL4630854] [UniProtKB: Q9GZZ1]
ChEMBL	Binding affinity to full length human N-terminal His-tagged/GST-tagged Naa50 expressed in Escherichia coli BL21(DE3) cells in by SPR analysis	B	6.81	pKd	156	nM	Kd	ACS Med Chem Lett (2020) 11: 1175-1184 [PMID:32550998]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]