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ChEMBL ligand: CHEMBL400875 (isradipine) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Cav1.1 in Human [GtoPdb: 528] [UniProtKB: Q13698] | ||||||||
GtoPdb | - | - | 9.7 | pKd | - | - | - | FEBS Lett (1985) 188: 222-6 [PMID:2411596] |
Cav1.1 in Rat [GtoPdb: 528] [UniProtKB: Q02485] | ||||||||
GtoPdb | - | - | 9.2 | pKd | - | - | - | Metab Clin Exp (1995) 44: 1455-61 [PMID:7476334] |
Cav1.2 in Human [GtoPdb: 529] [UniProtKB: Q13936] | ||||||||
GtoPdb | - | - | 11 | pKd | - | - | - | J Mol Cell Cardiol (1999) 31: 283-96 [PMID:10072735] |
Cav1.2 in Mouse [GtoPdb: 529] [UniProtKB: Q01815] | ||||||||
GtoPdb | - | - | 10.1 | pKd | - | - | - | J Clin Invest (2004) 113: 1430-9 [PMID:15146240] |
Cav1.3 in Human [GtoPdb: 530] [UniProtKB: Q01668] | ||||||||
GtoPdb | - | - | 9.4 | pKd | - | - | - | J Biol Chem (2001) 276: 22100-6 [PMID:11285265] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]