α-dendrotoxin [Ligand Id: 2563] activity data from GtoPdb

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  • Kv1.1 in Rat [GtoPdb: 538] [UniProtKB: P10499]
Created with Highcharts 10.3.3ValuesChart context menuKv1.1pKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
  • Kv1.2 in Rat [GtoPdb: 539] [UniProtKB: P63142]
Created with Highcharts 10.3.3ValuesChart context menuKv1.2pKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
  • Kv1.6 in Human [GtoPdb: 543] [UniProtKB: P17658]
Created with Highcharts 10.3.3ValuesChart context menuKv1.6pKd HumanpKi HumanpIC50 HumanpEC50 Human0246810Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Kv1.1 in Rat [GtoPdb: 538] [UniProtKB: P10499]
GtoPdb - - 9 pEC50 0.96 nM EC50 Mol Pharmacol (1994) 45: 1227-34 [PMID:7517498];
Mol Pharmacol (1991) 40: 572-6 [PMID:1921987]
Kv1.2 in Rat [GtoPdb: 539] [UniProtKB: P63142]
GtoPdb - - 9.4 pIC50 0.38 nM IC50 Mol Pharmacol (1994) 45: 1227-34 [PMID:7517498];
Mol Pharmacol (1991) 40: 572-6 [PMID:1921987]
Kv1.6 in Human [GtoPdb: 543] [UniProtKB: P17658]
GtoPdb - - 7.7 pIC50 19.9 nM IC50 EMBO J (1990) 9: 1749-56 [PMID:2347305]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.