margatoxin [Ligand Id: 2547] activity data from GtoPdb

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  • Kv1.1 in Human [GtoPdb: 538] [UniProtKB: Q09470]
  • Kv1.1 in Rat [GtoPdb: 538] [UniProtKB: P10499]
Created with Highcharts 10.3.3ValuesChart context menuKv1.1pKd HumanpKi HumanpIC50 HumanpEC50 HumanpKd RatpKi RatpIC50 RatpEC50 Rat0246810Highcharts.com
  • Kv1.2 in Human [GtoPdb: 539] [UniProtKB: P16389]
Created with Highcharts 10.3.3ValuesChart context menuKv1.2pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • Kv1.3 in Human [GtoPdb: 540] [UniProtKB: P22001]
Created with Highcharts 10.3.3ValuesChart context menuKv1.3pKd HumanpKi HumanpIC50 HumanpEC50 Human024681012Highcharts.com
  • Kv1.7 in Mouse [GtoPdb: 544] [UniProtKB: Q17ST2]
Created with Highcharts 10.3.3ValuesChart context menuKv1.7pKd MousepKi MousepIC50 MousepEC50 Mouse02468Highcharts.com
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Kv1.1 in Human [GtoPdb: 538] [UniProtKB: Q09470]
GtoPdb - - 8.4 pIC50 4.2 nM IC50 Toxicon (2014) 87: 6-16 [PMID:24878374]
Kv1.1 in Rat [GtoPdb: 538] [UniProtKB: P10499]
GtoPdb - - 8.3 pIC50 5.46 nM IC50 J Biol Chem (1997) 272: 27577-81 [PMID:9346893]
Kv1.2 in Human [GtoPdb: 539] [UniProtKB: P16389]
GtoPdb - - 11.2 pIC50 0.01 nM IC50 Toxicon (2014) 87: 6-16 [PMID:24878374]
Kv1.3 in Human [GtoPdb: 540] [UniProtKB: P22001]
GtoPdb - - 10.3 pIC50 0.05 nM IC50 J Biol Chem (2000) 275: 37137-49 [PMID:10961988];
J Biol Chem (1993) 268: 18866-74 [PMID:8360176]
Kv1.7 in Mouse [GtoPdb: 544] [UniProtKB: Q17ST2]
GtoPdb - - 6.9 pIC50 - - - J Biol Chem (1998) 273: 5851-7 [PMID:9488722]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.