Cd2+ [Ligand Id: 2440] activity data from GtoPdb

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  • CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5]
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  • CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9]
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  • CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99]
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  • CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3]
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  • TPC1 in Human [GtoPdb: 392] [UniProtKB: Q9ULQ1]
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  • TRPA1 in Human [GtoPdb: 485] [UniProtKB: O75762]
  • TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
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  • TRPC6 in Mouse [GtoPdb: 491] [UniProtKB: Q61143]
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  • Cav1.1 in Rat [GtoPdb: 528] [UniProtKB: Q02485]
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  • Cav1.2 in Rabbit [GtoPdb: 529]
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  • Cav2.1 in Rabbit [GtoPdb: 532]
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  • Cav2.3 in Human [GtoPdb: 534] [UniProtKB: Q15878]
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  • Nav1.7 in Human [GtoPdb: 584] [UniProtKB: Q15858]
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  • ASIC2 in Human [GtoPdb: 685] [UniProtKB: Q16515]
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  • ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793]
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  • Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96]
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  • NALCN in Human [GtoPdb: 750] [UniProtKB: Q8IZF0]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
CatSper1 in Mouse [GtoPdb: 388] [UniProtKB: Q91ZR5]
GtoPdb Whole cell patch clamp - 3.7 pIC50 200000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
CatSper2 in Mouse [GtoPdb: 389] [UniProtKB: A2ARP9]
GtoPdb Whole cell patch clamp. - 3.7 pIC50 200000 nM IC50 Mol Hum Reprod (2011) 17: 478-99 [PMID:21642646]
CatSper3 in Mouse [GtoPdb: 390] [UniProtKB: Q80W99]
GtoPdb Whole cell patch clamp electrophysiology. - 3.7 pIC50 200000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
CatSper4 in Mouse [GtoPdb: 391] [UniProtKB: Q8BVN3]
GtoPdb Whole cell patch clamp electrophysiology. - 3.7 pIC50 200000 nM IC50 Nature (2006) 439: 737-40 [PMID:16467839]
TPC1 in Human [GtoPdb: 392] [UniProtKB: Q9ULQ1]
GtoPdb - - 3.74 pIC50 180000 nM IC50 Nat Chem Biol (2014) 10: 463-9 [PMID:24776928]
TRPA1 in Human [GtoPdb: 485] [UniProtKB: O75762]
GtoPdb Sodium and calcium imaging - 5.85 pEC50 1400 nM EC50 Proc Natl Acad Sci USA (2009) 106: 8374-9 [PMID:19416844];
Mol Pain (2013) 9: 7 [PMID:23448290]
TRPA1 in Mouse [GtoPdb: 485] [UniProtKB: Q8BLA8]
GtoPdb - - 5.68 pEC50 2100 nM EC50 Proc Natl Acad Sci USA (2009) 106: 8374-9 [PMID:19416844];
Mol Pain (2013) 9: 7 [PMID:23448290]
TRPC6 in Mouse [GtoPdb: 491] [UniProtKB: Q61143]
GtoPdb - - 3.6 pIC50 253000 nM IC50 Circ Res (2001) 88: 325-32 [PMID:11179201]
Cav1.1 in Rat [GtoPdb: 528] [UniProtKB: Q02485]
GtoPdb - - 4.3 pIC50 - - - J Gen Physiol (1988) 91: 781-98 [PMID:2458429]
Cav1.2 in Rabbit [GtoPdb: 529]
GtoPdb - - 6 pIC50 - - - Am J Physiol (1997) 272: H2164-72 [PMID:9176282]
Cav2.1 in Rabbit [GtoPdb: 532]
GtoPdb - - 6.3 pIC50 - - -
Cav2.3 in Human [GtoPdb: 534] [UniProtKB: Q15878]
GtoPdb - - 6.1 pIC50 - - - J Biol Chem (1994) 269: 22347-57 [PMID:8071363]
Nav1.7 in Human [GtoPdb: 584] [UniProtKB: Q15858]
GtoPdb - - 3 pIC50 - - - EMBO J (1995) 14: 1084-90 [PMID:7720699]
ASIC2 in Human [GtoPdb: 685] [UniProtKB: Q16515]
GtoPdb - - 3 pIC50 ~1000000 nM IC50 Dev Neurobiol (2007) 67: 97-107 [PMID:17443775]
ClC-4 in Human [GtoPdb: 703] [UniProtKB: P51793]
GtoPdb - - 4.2 pIC50 68000 nM IC50 Biophys J (2008) 95: 4668-75 [PMID:18658230]
Hv1 in Human [GtoPdb: 746] [UniProtKB: Q96D96]
GtoPdb - - 5 pIC50 ~10000 nM IC50
NALCN in Human [GtoPdb: 750] [UniProtKB: Q8IZF0]
GtoPdb - - 3.8 pIC50 150000 nM IC50

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.