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ChEMBL ligand: CHEMBL931 (Fluothane, FREON 123B1, Halothane, Halothanum, NSC-143490, Rhidialothan) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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TRPM3 in Human [GtoPdb: 495] [UniProtKB: Q9HCF6] | ||||||||
GtoPdb | - | - | 3.28 | pIC50 | 520000 | nM | IC50 | Biochem Pharmacol (2020) 174: 113826 [PMID:31987857] |
K2P3.1 in Rat [GtoPdb: 515] [UniProtKB: O54912] | ||||||||
GtoPdb | - | - | 3 | pEC50 | 1000000 | nM | EC50 |
J Neurosci (2002) 22: 1256-65 [PMID:11850453]; EMBO J (1998) 17: 4283-90 [PMID:9687497] |
K2P5.1 in Human [GtoPdb: 517] [UniProtKB: O95279] | ||||||||
GtoPdb | - | - | 3.7 | pIC50 | - | - | - | Anesthesiology (2000) 92: 1722-30 [PMID:10839924] |
Kv2.1 in Rat [GtoPdb: 546] [UniProtKB: P15387] | ||||||||
GtoPdb | - | - | 3.5 | pEC50 | - | - | - | Anesthesiology (1996) 84: 900-9 [PMID:8638845] |
ChEMBL data shown on this page come from version 32:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]