PHI [Ligand Id: 2273] activity data from GtoPdb

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  • VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241]
  • VPAC1 receptor in Rat [GtoPdb: 371] [UniProtKB: P30083]
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  • VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587]
  • VPAC2 receptor in Rat [GtoPdb: 372] [UniProtKB: P35000]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
VPAC1 receptor in Human [GtoPdb: 371] [UniProtKB: P32241]
GtoPdb inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor - 6 pIC50 1000 nM IC50 Ann. N. Y. Acad. Sci. (1998) 865: 247-52 [PMID:9928018]
VPAC1 receptor in Rat [GtoPdb: 371] [UniProtKB: P30083]
GtoPdb inhibition of [125I]-VIP binding to membranes from CHO cells stably expressing the recombinant receptor - 8.5 pIC50 3 nM IC50 Ann. N. Y. Acad. Sci. (1998) 865: 247-52 [PMID:9928018]
VPAC2 receptor in Human [GtoPdb: 372] [UniProtKB: P41587]
GtoPdb inhibition of [125I]Ro25 1553 binding to membranes from CHO cells stably expressing the recombinant receptor - 7.5 pIC50 30 nM IC50 Ann. N. Y. Acad. Sci. (1998) 865: 247-52 [PMID:9928018]
VPAC2 receptor in Rat [GtoPdb: 372] [UniProtKB: P35000]
GtoPdb inhibition of [125I]Ro25 1553 binding to membranes from CHO cells stably expressing the recombinant receptor - 7.5 pIC50 30 nM IC50 Ann. N. Y. Acad. Sci. (1998) 865: 247-52 [PMID:9928018]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.