U46609 [Ligand Id: 1972] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL2074582 (Prostaglandin H2) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| OATP2A1/Solute carrier organic anion transporter family member 2A1 in Rat (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL2073680] [GtoPdb: 1223] [UniProtKB: Q00910] | ||||||||
| ChEMBL | TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cells | F | 7.42 | pKi | 38.2 | nM | Ki | Mol Pharmacol (1996) 50: 738-742 [PMID:8863817] |
| TP receptor in Human [GtoPdb: 346] [UniProtKB: P21731] | ||||||||
| GtoPdb | - | - | 8.4 | pKi | - | - | - | Jpn J Pharmacol (1992) 59: 357-64 [PMID:1434130] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
