compound 1 [PMID: 33929818] [Ligand Id: 11709] activity data from GtoPdb

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum TM90C2B [GtoPdb: 3056]
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum K1 [GtoPdb: 3056]
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum NF54 [GtoPdb: 3056]
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7]
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum 7G8 [GtoPdb: 3056]
  • Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum Dd2 [GtoPdb: 3056]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum TM90C2B [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.77 pIC50 17 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum K1 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.7 pIC50 20 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum NF54 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.74 pIC50 18 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum 3D7 [GtoPdb: 3056] [UniProtKB: Q8I5R7]
GtoPdb Parasite growth inhibition assay - 8 pIC50 10 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum 7G8 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.74 pIC50 18 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]
Plasmodium falciparum proline--tRNA ligase in Plasmodium falciparum Dd2 [GtoPdb: 3056]
GtoPdb Parasite growth inhibition assay - 7.62 pIC50 24 nM IC50 ACS Infect Dis (2021) 7: 1680-1689 [PMID:33929818]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.