TYK2 inhibitor 14l [Ligand Id: 11425] activity data from GtoPdb

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  • Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
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  • tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Janus kinase 2 in Human [GtoPdb: 2048] [UniProtKB: O60674]
GtoPdb - - 6.8 pIC50 157 nM IC50 Journal of Medicinal Chemistry (2021) : [PMID:33593051]
tyrosine kinase 2 in Human [GtoPdb: 2269] [UniProtKB: P29597]
GtoPdb - - 8.05 pIC50 9 nM IC50 Journal of Medicinal Chemistry (2021) : [PMID:33593051]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.