WM382 [Ligand Id: 11162] activity data from GtoPdb

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  • Plasmodium falciparum plasmepsin X in Plasmodium falciparum [GtoPdb: 3071]
  • Plasmodium falciparum plasmepsin X in Plasmodium falciparum K1 [GtoPdb: 3071]
  • Plasmodium falciparum plasmepsin X in Plasmodium knowlesi [GtoPdb: 3071]
  • Plasmodium falciparum plasmepsin X in Plasmodium falciparum 3D7 [GtoPdb: 3071]
  • Plasmodium falciparum plasmepsin X in Plasmodium falciparum Dd2 [GtoPdb: 3071]
  • This target only has 1 pki data point
1 _lig_chart_1 Plasmodium falciparum plasmepsin X Plasmodium falciparumPlasmodium falciparum K1Plasmodium knowlesiPlasmodium falciparum 3D7Plasmodium falciparum Dd2
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum plasmepsin X in Plasmodium falciparum [GtoPdb: 3071]
GtoPdb Peptide cleavage assay using recombinant PMX - 10.46 pKi 0.04 nM Ki Cell Host Microbe (2020) 27: 642-658.e12 [PMID:32109369]
Plasmodium falciparum plasmepsin X in Plasmodium falciparum K1 [GtoPdb: 3071]
GtoPdb Parasite growth inhibition assay - 9.19 pEC50 0.65 nM EC50 Cell Host Microbe (2020) 27: 642-658.e12 [PMID:32109369]
Plasmodium falciparum plasmepsin X in Plasmodium knowlesi [GtoPdb: 3071]
GtoPdb Parasite growth inhibition assay - 9.74 pEC50 0.18 nM EC50 Cell Host Microbe (2020) 27: 642-658.e12 [PMID:32109369]
Plasmodium falciparum plasmepsin X in Plasmodium falciparum 3D7 [GtoPdb: 3071]
GtoPdb Parasite growth inhibition assay - 9.22 pEC50 0.6 nM EC50 Cell Host Microbe (2020) 27: 642-658.e12 [PMID:32109369]
Plasmodium falciparum plasmepsin X in Plasmodium falciparum Dd2 [GtoPdb: 3071]
GtoPdb Parasite growth inhibition assay - 9.59 pEC50 0.26 nM EC50 Cell Host Microbe (2020) 27: 642-658.e12 [PMID:32109369]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.