MC2050 [Ligand Id: 10671] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| poly(ADP-ribose) polymerase 1 in Human [GtoPdb: 2771] [UniProtKB: P09874] | ||||||||
| GtoPdb | inhibitory capacity of MC2050 in vitro on recombinant PARP1. | - | 6.92 | pIC50 | 119 | nM | IC50 | ChemMedChem (2011) 6: 606-11 [PMID:21365766] |
| GtoPdb | - | - | 8.03 | pIC50 | 9.3 | nM | IC50 | ACS Med Chem Lett (2020) : |
| poly(ADP-ribose) polymerase 2 in Human [GtoPdb: 2772] [UniProtKB: Q9UGN5] | ||||||||
| GtoPdb | Inhibitory effect of MC2050 in vitro on recombinant PARP2. | - | 5.74 | pIC50 | 1800 | nM | IC50 | ChemMedChem (2011) 6: 606-11 [PMID:21365766] |
| GtoPdb | - | - | 6.26 | pIC50 | 549 | nM | IC50 | ACS Med Chem Lett (2020) : |
| tankyrase in Human [GtoPdb: 3108] [UniProtKB: O95271] | ||||||||
| GtoPdb | - | - | 6.66 | pIC50 | 218 | nM | IC50 | ACS Med Chem Lett (2020) : |
| tankyrase 2 in Human [GtoPdb: 3109] [UniProtKB: Q9H2K2] | ||||||||
| GtoPdb | - | - | 6.71 | pIC50 | 193 | nM | IC50 | ACS Med Chem Lett (2020) : |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
