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ChEMBL ligand: CHEMBL2110755 (Avitriptan) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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5-HT1A receptor in Rat [GtoPdb: 1] [UniProtKB: P19327] | ||||||||
GtoPdb | - | - | 7.15 | pKi | 70.8 | nM | Ki | Naunyn Schmiedebergs Arch Pharmacol (1997) 355: 295-302 [PMID:9050026] |
5-HT1B receptor in Human [GtoPdb: 2] [UniProtKB: P28222] | ||||||||
GtoPdb | - | - | 7.68 | pKi | 20.9 | nM | Ki | Naunyn Schmiedebergs Arch Pharmacol (1997) 355: 295-302 [PMID:9050026] |
5-HT1B receptor in Rat [GtoPdb: 2] [UniProtKB: P28564] | ||||||||
GtoPdb | - | - | 7.44 | pKi | 36.3 | nM | Ki | Naunyn Schmiedebergs Arch Pharmacol (1997) 355: 295-302 [PMID:9050026] |
5-HT1D receptor in Human [GtoPdb: 3] [UniProtKB: P28221] | ||||||||
GtoPdb | - | - | 8.36 | pKi | 4.37 | nM | Ki | Naunyn Schmiedebergs Arch Pharmacol (1997) 355: 295-302 [PMID:9050026] |
ChEMBL data shown on this page come from version 33:
Mendez D, Gaulton A, Bento AP, Chambers J, De Veij M, Félix E, Magariños MP, Mosquera JF, Mutowo P, Nowotka M, Gordillo-Marañón M, Hunter F, Junco L, Mugumbate G, Rodriguez-Lopez M, Atkinson F, Bosc N, Radoux CJ, Segura-Cabrera A, Hersey A, Leach AR. (2019) 'ChEMBL: towards direct deposition of bioassay data' Nucleic Acids Res., 47(D1). DOI: 10.1093/nar/gky1075. [EPMCID:30398643]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]