compound 5 [PMID: 30894487] [Ligand Id: 10398] activity data from GtoPdb and ChEMBL

Click here for a description of the charts and data table

Please tell us if you are using this feature and what you think!

ChEMBL ligand: CHEMBL3989220
  • Plasmodium falciparum lysine--tRNA ligase in Plasmodium falciparum K1 [GtoPdb: 3059]
  • Plasmodium falciparum lysine--tRNA ligase in Plasmodium falciparum NF54 [GtoPdb: 3059]
  • Plasmodium falciparum lysine--tRNA ligase in Plasmodium vivax [GtoPdb: 3059]
  • Plasmodium falciparum lysine--tRNA ligase in Plasmodium falciparum 3D7 [GtoPdb: 3059] [UniProtKB: Q8IDJ8]
There should be some charts here, you may need to enable JavaScript!
DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Plasmodium falciparum lysine--tRNA ligase in Plasmodium falciparum K1 [GtoPdb: 3059]
GtoPdb Parasite growth inhibition assay - 6.29 pEC50 510 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2019) 116: 7015-7020 [PMID:30894487]
Plasmodium falciparum lysine--tRNA ligase in Plasmodium falciparum NF54 [GtoPdb: 3059]
GtoPdb Parasite stage V gametocyte assay - 5 pEC50 9900 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2019) 116: 7015-7020 [PMID:30894487]
GtoPdb Parasite gamete formation assay - 6 pEC50 >1000 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2019) 116: 7015-7020 [PMID:30894487]
GtoPdb Parasite growth inhibition assay - 6.41 pEC50 390 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2019) 116: 7015-7020 [PMID:30894487]
Plasmodium falciparum lysine--tRNA ligase in Plasmodium vivax [GtoPdb: 3059]
GtoPdb Parasite liver stage assay - 6.02 pEC50 950 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2019) 116: 7015-7020 [PMID:30894487]
Plasmodium falciparum lysine--tRNA ligase in Plasmodium falciparum 3D7 [GtoPdb: 3059] [UniProtKB: Q8IDJ8]
GtoPdb Parasite growth inhibition assay - 6.57 pEC50 270 nM EC50 Proc. Natl. Acad. Sci. U.S.A. (2019) 116: 7015-7020 [PMID:30894487]

ChEMBL data shown on this page come from version 27:

Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]