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ChEMBL ligand: CHEMBL380230 (Arteflene, RO 42-1611, RO-421611, RO-42-1611) |
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DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
ChEMBL | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 | F | 7.12 | pIC50 | 76 | nM | IC50 | Bioorg. Med. Chem. Lett. (2006) 16: 2991-2995 [PMID:16527481] |
ChEMBL | In vitro antimalarial activity against chloroquine-sensitive Plasmodium falciparum NF 54 | F | 7.15 | pIC50 | 71 | nM | IC50 | Bioorg. Med. Chem. Lett. (1998) 8: 903-908 [PMID:9871509] |
Plasmodium falciparum (isolate K1 / Thailand) in Plasmodium falciparum K1 (target type: ORGANISM) [ChEMBL: CHEMBL612856] | ||||||||
ChEMBL | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 assessed as inhibition of parasite growth | F | 7.82 | pIC50 | 15 | nM | IC50 | Bioorg. Med. Chem. (2015) 23: 5120-5130 [PMID:25913864] |
ChEMBL data shown on this page come from version 31:
Gaulton A, Hersey A, Nowotka M, Bento AP, Chambers J, Mendez D, Mutowo P, Atkinson F, Bellis LJ, CibriƔn-Uhalte E, Davies M, Dedman N, Karlsson A, MagariƱos MP, Overington JP, Papadatos G, Smit I, Leach AR. (2017) 'The ChEMBL database in 2017.' Nucleic Acids Res., 45(D1). DOI: 10.1093/nar/gkw1074. [PMCID:5210557]