arteflene [Ligand Id: 10397] activity data from GtoPdb and ChEMBL
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| ChEMBL ligand: CHEMBL380230 (Arteflene, Artefleno, RO 42-1611, RO-42-1611, RO-421611) |
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
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| Plasmodium falciparum (target type: ORGANISM) [ChEMBL: CHEMBL364] | ||||||||
| ChEMBL | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 | F | 7.12 | pIC50 | 76 | nM | IC50 | Bioorg Med Chem Lett (2006) 16: 2991-2995 [PMID:16527481] |
| ChEMBL | In vitro antimalarial activity against chloroquine-sensitive Plasmodium falciparum NF 54 | F | 7.15 | pIC50 | 71 | nM | IC50 | Bioorg Med Chem Lett (1998) 8: 903-908 [PMID:9871509] |
| ChEMBL | Antimalarial activity against chloroquine-resistant Plasmodium falciparum K1 assessed as inhibition of parasite growth | F | 7.82 | pIC50 | 15 | nM | IC50 | Bioorg Med Chem (2015) 23: 5120-5130 [PMID:25913864] |
ChEMBL data shown on this page come from version 34:
Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]
