SZM594 [Ligand Id: 10388] activity data from GtoPdb

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  • B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
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  • receptor interacting serine/threonine kinase 1 in Human [GtoPdb: 2189] [UniProtKB: Q13546]
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  • receptor interacting serine/threonine kinase 3 in Human [GtoPdb: 2191] [UniProtKB: Q9Y572]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
B-Raf proto-oncogene, serine/threonine kinase in Human [GtoPdb: 1943] [UniProtKB: P15056]
GtoPdb Determined in a Latha screen assay. - 6.49 pIC50 322 nM IC50 Br J Pharmacol (2019) 176: 2095-2108 [PMID:30825190]
receptor interacting serine/threonine kinase 1 in Human [GtoPdb: 2189] [UniProtKB: Q13546]
GtoPdb Determined in a KINOMEscan assay. - 7.01 pKd 97 nM Kd Br J Pharmacol (2019) 176: 2095-2108 [PMID:30825190]
receptor interacting serine/threonine kinase 3 in Human [GtoPdb: 2191] [UniProtKB: Q9Y572]
GtoPdb Determined in a KINOMEscan assay. - 7.11 pKd 77 nM Kd Br J Pharmacol (2019) 176: 2095-2108 [PMID:30825190]

Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.