SAG1.3 [Ligand Id: 10327] activity data from GtoPdb
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| DB | Assay description | Assay Type | Standard value | Standard parameter | Original value | Original units | Original parameter | Reference |
|---|---|---|---|---|---|---|---|---|
| FZD6 in Human [GtoPdb: 234] [UniProtKB: O60353] | ||||||||
| GtoPdb | Determined in a displacement NanoBRET assay using BODIPY–cyclopamine and nanoluciferase (Nluc)-tagged FZD6, in cells with CRISPR/Cas9 disabled SMO expression. | - | 5.6 | pKd | 2510 | nM | Kd | Nat Commun (2020) 11: 414 [PMID:31964872] |
| SMO in Mouse [GtoPdb: 239] [UniProtKB: P56726] | ||||||||
| GtoPdb | Measuring Hh pathway activation in Gli-dependent reporter assays in Shh-LIGHT2 cells. | - | 8.52 | pEC50 | 3 | nM | EC50 | Proc Natl Acad Sci USA (2002) 99: 14071-6 [PMID:12391318] |
Our curators have not yet identified this ligand in ChEMBL, but you may find additional data by searching on the ChEMBL site using the ligand's name or structure.
