Estrogen-related receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Nuclear Hormone Receptors [1]) have yet to be officially paired with an endogenous ligand.

* Key recommended reading is highlighted with an asterisk

* Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev, 58 (4): 798-836. [PMID:17132856]

Deblois G, Giguère V. (2011) Functional and physiological genomics of estrogen-related receptors (ERRs) in health and disease. Biochim Biophys Acta, 1812 (8): 1032-40. [PMID:21172432]

Deblois G, Giguère V. (2013) Oestrogen-related receptors in breast cancer: control of cellular metabolism and beyond. Nat Rev Cancer, 13 (1): 27-36. [PMID:23192231]

* Divekar SD, Tiek DM, Fernandez A, Riggins RB. (2016) Estrogen-related receptor β (ERRβ) - renaissance receptor or receptor renaissance?. Nucl Recept Signal, 14: e002. [PMID:27507929]

* Germain P, Staels B, Dacquet C, Spedding M, Laudet V. (2006) Overview of nomenclature of nuclear receptors. Pharmacol Rev, 58 (4): 685-704. [PMID:17132848]

Gonzalez-Sanchez E, Firrincieli D, Housset C, Chignard N. (2015) Nuclear receptors in acute and chronic cholestasis. Dig Dis, 33 (3): 357-66. [PMID:26045270]

Huang P, Chandra V, Rastinejad F. (2010) Structural overview of the nuclear receptor superfamily: insights into physiology and therapeutics. Annu Rev Physiol, 72: 247-72. [PMID:20148675]

Hwang-Verslues WW, Sladek FM. (2010) HNF4α--role in drug metabolism and potential drug target?. Curr Opin Pharmacol, 10 (6): 698-705. [PMID:20833107]

Sladek FM. (2011) What are nuclear receptor ligands?. Mol Cell Endocrinol, 334 (1-2): 3-13. [PMID:20615454]

* Tam IS, Giguère V. (2016) There and back again: The journey of the estrogen-related receptors in the cancer realm. J Steroid Biochem Mol Biol, 157: 13-9. [PMID:26151739]

* Wu D, Cheung A, Wang Y, Yu S, Chan FL. (2016) The emerging roles of orphan nuclear receptors in prostate cancer. Biochim Biophys Acta, 1866 (1): 23-36. [PMID:27264242]

1. Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. (2006) International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev, 58 (4): 798-836. [PMID:17132856]

2. Suetsugi M, Su L, Karlsberg K, Yuan YC, Chen S. (2003) Flavone and isoflavone phytoestrogens are agonists of estrogen-related receptors. Mol Cancer Res, 1 (13): 981-91. [PMID:14638870]

3. Willy PJ, Murray IR, Qian J, Busch BB, Stevens WC, Martin R, Mohan R, Zhou S, Ordentlich P, Wei P, Sapp DW, Horlick RA, Heyman RA, Schulman IG. (2004) Regulation of PPARgamma coactivator 1alpha (PGC-1alpha) signaling by an estrogen-related receptor alpha (ERRalpha) ligand. Proc Natl Acad Sci USA, 101 (24): 8912-7. [PMID:15184675]

4. Yu DD, Forman BM. (2005) Identification of an agonist ligand for estrogen-related receptors ERRbeta/gamma. Bioorg Med Chem Lett, 15 (5): 1311-3. [PMID:15713377]

5. Zuercher WJ, Gaillard S, Orband-Miller LA, Chao EY, Shearer BG, Jones DG, Miller AB, Collins JL, McDonnell DP, Willson TM. (2005) Identification and structure-activity relationship of phenolic acyl hydrazones as selective agonists for the estrogen-related orphan nuclear receptors ERRbeta and ERRgamma. J Med Chem, 48 (9): 3107-9. [PMID:15857113]