Protein kinase G (PKG) family

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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).

Overview

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Cyclic GMP-dependent protein kinase is a dimeric enzyme activated by cyclic GMP generated by particulate guanylyl cyclases or soluble guanylyl cyclases.

Enzymes

PKG1 (Protein kinase G (PKG) 1) Show summary »« Hide summary More detailed page go icon to follow link

PKG2 (Protein kinase G (PKG) 2) Show summary »« Hide summary More detailed page go icon to follow link

References

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How to cite this family page

Database page citation:

Protein kinase G (PKG) family. Accessed on 18/08/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=287.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Fabbro D, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Armstrong JF, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Enzymes. Br J Pharmacol. 182: S307-S403.