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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
Inositol 1,4,5-trisphosphate 3-kinases (E.C. 2.7.1.127, ENSFM00250000001260) catalyse the generation of inositol 1,3,4,5-tetrakisphosphate (IP4) from IP3. IP3 kinase activity is enhanced in the presence of calcium/calmodulin (CALM2, CALM3, CALM1, P62158) [1].
IP3 kinase A Show summary » |
IP3 kinase B
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IP3 kinase C Show summary » |
Database page citation:
Inositol 1,4,5-trisphosphate 3-kinases. Accessed on 10/12/2023. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=280.
Concise Guide to PHARMACOLOGY citation:
Alexander SP, Fabbro D, Kelly E, Mathie A, Peters JA, Veale EL et al. (2021) THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes. Br J Pharmacol. 178 Suppl 1:S313-S411.