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Unless otherwise stated all data on this page refer to the human proteins. Gene information is provided for human (Hs), mouse (Mm) and rat (Rn).
CYP24s deactivate vitamin D metabolites and CYP27s are required for the biosynthesis of vitamin D from cholesterol. CYP26 enzymes metabolise excess all-trans-retinol to limit toxicity.
Vitamin D3 24-hydroxylase (CYP24A1) C Show summary » |
CYP26A1
C
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CYP26B1 C Show summary » |
CYP26C1 C Show summary » |
Sterol 27-hydroxylase (CYP27A1) C Show summary » |
25-Hydroxyvitamin D 1-alpha-hydroxylase (CYP27B1) C Show summary » |
CYP27C1 C Show summary » |
Database page citation (select format):
Concise Guide to PHARMACOLOGY citation:
Alexander SPH, Fabbro D, Kelly E, Mathie AA, Peters JA, Veale EL, Armstrong JF, Faccenda E, Harding SD, Davies JA et al. (2023) The Concise Guide to PHARMACOLOGY 2023/24: Enzymes. Br J Pharmacol. 180 Suppl 2:S289-373.