Coenzyme A synthesis pathway enzymes

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Overview

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The five enzymatic steps of the Coenzyme A (CoA) synthesis pathway are highly conserved, however the amino acid sequences of the enzymes catalysing the reactions show low conservation between species.

The P. falciparum CoA synthesis pathway. Identifiers (PlasmoDB) of the putative P. falciparum enzymes are shown in dark blue boxes.

Targets

PfPANK1 (Plasmodium falciparum pantothenate kinase 1) C Show summary »« Hide summary More detailed page go icon to follow link

Target Id	3089
Nomenclature	Plasmodium falciparum pantothenate kinase 1
Common abbreviation	PfPANK1
Previous and unofficial names	PANK1 \| Pf3D7_14_v3:853,711..856,441(-) \| PANK \| pantothenate kinase 1, putative \| PF14_0200
Genes	PANK1 (Pf3D7)
UniProtKB AC	Q8ILP4 (Pf3D7)
PlasmoDB	PF3D7_1420600 (Pf3D7)

How to cite this family page

Database page citation:

Coenzyme A synthesis pathway enzymes. Accessed on 05/04/2026. IUPHAR/BPS Guide to PHARMACOLOGY, http://www.guidetopharmacology.org/GRAC/FamilyDisplayForward?familyId=1053.

Concise Guide to PHARMACOLOGY citation:

Alexander SPH, Gibb AJ, Kelly E, Mathie AA, Peach CJ, Veale EL, Cidlowski JA, Davenport AP, Fabbro D, Spedding M, Striessnig J, Armstrong JF, Buneman OP, Faccenda E, Harding SD, Southan C, Davies JA et al. (2025) The Concise Guide to PHARMACOLOGY 2025/26: Introduction and Other Protein Targets. Br J Pharmacol. 182: S1-S23.