"# GtoPdb Version: 2026.2 - published: 2026-06-15"
"Ligand ID"	"Name"	"Species"	"Type"	"Approved"	"Withdrawn"	"Labelled"	"Radioactive"	"PubChem SID"	"PubChem CID"	"UniProt ID"	"Ensembl ID"	"ChEMBL ID"	"Ligand Subunit IDs"	"Ligand Subunit Name"	"Ligand Subunit UniProt IDs"	"Ligand Subunit Ensembl IDs"	"IUPAC name"	"INN"	"Synonyms"	"SMILES"	"InChIKey"	"InChI"	"GtoImmuPdb"	"GtoMPdb"	"Antibacterial"
"5102"	"1400W"	""	"Synthetic organic"	""	""	""	""	"178101795"	"1433"	""	""	"CHEMBL107251"	""	""	""	""	"(E)-N'-{[3-(aminomethyl)phenyl]methyl}ethenimidamide"	""	"W 1400"	"NCc1cccc(c1)C/N=C(/N)\C"	"RODUKNYOEVZQPR-UHFFFAOYSA-N"	"InChI=1S/C10H15N3/c1-8(12)13-7-10-4-2-3-9(5-10)6-11/h2-5H,6-7,11H2,1H3,(H2,12,13)"	"yes"	""	""
"13464"	"14-Deoxy-11,12-didehydroandrographolide"	""	"Natural product"	""	""	""	""	"500839874"	"5708351"	""	""	"CHEMBL361568"	""	""	""	""	"4-[(E)-2-[(1R,4aS,5R,6R,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethenyl]-2H-furan-5-one"	""	"ddA (14-deoxy-11,12-didehydroandrographolide)"	"[H][C@]12CCC(=C)[C@@H](/C=C/C3=CCOC3=O)[C@]1(C)CC[C@@H](O)[C@@]2(C)CO"	"XMJAJFVLHDIEHF-CRBRZBHVSA-N"	"InChI=1S/C20H28O4/c1-13-4-7-16-19(2,10-8-17(22)20(16,3)12-21)15(13)6-5-14-9-11-24-18(14)23/h5-6,9,15-17,21-22H,1,4,7-8,10-12H2,2-3H3/b6-5+/t15-,16+,17-,19+,20+/m1/s1"	"yes"	""	""
"8851"	"17-octadecynoic acid"	""	"Synthetic organic"	""	""	""	""	"252827508"	"1449"	""	""	"CHEMBL182310"	""	""	""	""	"octadec-17-ynoic acid"	""	"17-ODYA"	"C#CCCCCCCCCCCCCCCCC(=O)O"	"DZIILFGADWDKMF-UHFFFAOYSA-N"	"InChI=1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h1H,3-17H2,(H,19,20)"	"yes"	""	""
"5106"	"18S-resolvin E1"	""	"Metabolite"	""	""	""	""	"178101799"	"52921890"	""	""	""	""	""	""	""	"(5S,6Z,8E,10E,12R,14Z,16E,18S)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid"	""	"18S-RvE1"	"CC[C@@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O"	"AOPOCGPBAIARAV-JJVMZPRHSA-N"	"InChI=1S/C20H30O5/c1-2-17(21)11-8-5-9-14-18(22)12-6-3-4-7-13-19(23)15-10-16-20(24)25/h3-9,11-13,17-19,21-23H,2,10,14-16H2,1H3,(H,24,25)/b4-3+,9-5-,11-8+,12-6+,13-7-/t17-,18-,19+/m0/s1"	"yes"	""	""
"10138"	"1R-11"	""	"Synthetic organic"	""	""	""	""	"381118848"	"134264089"	""	""	""	""	""	""	""	"methyl (E,5S,6R)-5,6-dihydroxy-8-[5-[(1R)-1-hydroxyhexyl]-1,2-dimethylimidazol-4-yl]oct-7-enoate"	""	""	"CCCCC[C@H](c1c(/C=C/[C@H]([C@H](CCCC(=O)OC)O)O)nc(n1C)C)O"	"PLBGFBROZZUTKG-PHCFSIKCSA-N"	"InChI=1S/C20H34N2O5/c1-5-6-7-9-18(25)20-15(21-14(2)22(20)3)12-13-17(24)16(23)10-8-11-19(26)27-4/h12-13,16-18,23-25H,5-11H2,1-4H3/b13-12+/t16-,17+,18+/m0/s1"	"yes"	""	""
"9207"	"2'3'-cGAMP"	""	"Metabolite"	""	""	""	""	"315661283"	"135564529"	""	""	""	""	""	""	""	""	""	"cyclic [G(2',5')pA(3',5')p]|cyclic GMP-AMP|Cyclic guanosine monophosphate-adenosine monophosphate"	"Nc1nc(=O)c2c([nH]1)n(cn2)[C@@H]1O[C@H]2[C@H]([C@H]1OP(=O)(O)OC[C@@H]1[C@@H](OP(=O)(OC2)O)[C@H]([C@@H](O1)n1cnc2c1ncnc2N)O)O"	"XRILCFTWUCUKJR-INFSMZHSSA-N"	"InChI=1S/C20H24N10O13P2/c21-14-8-15(24-3-23-14)29(4-25-8)18-11(32)12-7(41-18)2-39-45(36,37)43-13-10(31)6(1-38-44(34,35)42-12)40-19(13)30-5-26-9-16(30)27-20(22)28-17(9)33/h3-7,10-13,18-19,31-32H,1-2H2,(H,34,35)(H,36,37)(H2,21,23,24)(H3,22,27,28,33)/t6-,7-,10-,11-,12-,13-,18-,19-/m1/s1"	"yes"	""	""
"1197"	"2-pyridylethylamine"	""	"Synthetic organic"	""	""	""	""	"135649712"	"75919"	""	""	"CHEMBL32813"	""	""	""	""	"2-pyridin-2-ylethanamine"	""	"PEA"	"NCCc1ccccn1"	"XPQIPUZPSLAZDV-UHFFFAOYSA-N"	"InChI=1S/C7H10N2/c8-5-4-7-3-1-2-6-9-7/h1-3,6H,4-5,8H2"	"yes"	""	""
"9564"	"3 alpha-aminocholestane"	""	"Synthetic organic"	""	""	""	""	"336446950"	"10872780"	""	""	""	""	""	""	""	"(3R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-amine"	""	"3 α-aminocholestane|3AC"	"CC(CCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CCC2[C@]1(C)CC[C@H](C2)N)C)C"	"RJNGJYWAIUJHOJ-DSHIFKSRSA-N"	"InChI=1S/C27H49N/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h18-25H,6-17,28H2,1-5H3/t19-,20?,21-,22+,23-,24+,25+,26+,27-/m1/s1"	"yes"	""	""
"9028"	"3beta-Hydroxy-20(29)-lupene"	""	"Synthetic organic"	""	""	""	""	"315661113"	"16219576"	""	""	""	""	""	""	""	"(5aR,7aR,13bR)-3a,5a,5b,8,8,11a-hexamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-ol"	""	"Fagarasterol|Lupeol"	"CC(=C)C1CCC2([C@H]1C1CCC3C([C@]1(C)CC2)(C)CC[C@@H]1C3(C)CCC(C1(C)C)O)C"	"MQYXUWHLBZFQQO-HQBMYVNCSA-N"	"InChI=1S/C30H50O/c1-19(2)20-11-14-27(5)17-18-29(7)21(25(20)27)9-10-23-28(6)15-13-24(31)26(3,4)22(28)12-16-30(23,29)8/h20-25,31H,1,9-18H2,2-8H3/t20?,21?,22-,23?,24?,25+,27?,28?,29+,30?/m0/s1"	"yes"	""	""
"9270"	"3M-002"	""	"Synthetic organic"	""	""	""	""	"315661345"	"10198719"	""	""	"CHEMBL512901"	""	""	""	""	"2-propyl-[1,3]thiazolo[4,5-c]quinolin-4-amine"	""	"CL-075|CL075"	"CCCc1nc2c(s1)c1ccccc1nc2N"	"NFYMGJSUKCDVJR-UHFFFAOYSA-N"	"InChI=1S/C13H13N3S/c1-2-5-10-16-11-12(17-10)8-6-3-4-7-9(8)15-13(11)14/h3-4,6-7H,2,5H2,1H3,(H2,14,15)"	"yes"	""	""
"10562"	"4-OMe-ARM1"	""	"Synthetic organic"	""	""	""	""	"404859009"	"145704648"	""	""	""	""	""	""	""	"4-(4-{[4-(Methoxy)phenyl]methyl}phenyl)-1,3-thiazol-2-ylamine"	""	"compound 7 [PMID: 31751136]"	"COc1ccc(cc1)Cc1ccc(cc1)c1csc(n1)N"	"GGCCOFFVKJCRKJ-UHFFFAOYSA-N"	"InChI=1S/C17H16N2OS/c1-20-15-8-4-13(5-9-15)10-12-2-6-14(7-3-12)16-11-21-17(18)19-16/h2-9,11H,10H2,1H3,(H2,18,19)"	"yes"	""	""
"11900"	"5-hydroxyindoleacetic acid"	""	"Synthetic organic"	""	""	""	""	"461663455"	"1826"	""	""	"CHEMBL395915"	""	""	""	""	"2-(5-hydroxy-1H-indol-3-yl)acetic acid"	""	""	"c1cc2c(cc1O)c(c[nH]2)CC(=O)O"	"DUUGKQCEGZLZNO-UHFFFAOYSA-N"	"InChI=1S/C10H9NO3/c12-7-1-2-9-8(4-7)6(5-11-9)3-10(13)14/h1-2,4-5,11-12H,3H2,(H,13,14)"	"yes"	""	""
"5183"	"5-LOX activating protein"	"Human"	"Peptide"	""	""	""	""	"178101873"	""	"P20292"	"ENSG00000132965"	""	""	""	""	""	""	""	"5-lipoxygenase-activating protein|arachidonate 5-lipoxygenase-activating protein|FLAP"	""	""	""	"yes"	""	""
"10079"	"5-LOX inhibitor 2m [PMID: 30199704]"	""	"Synthetic organic"	""	""	""	""	"375973266"	"134813912"	""	""	""	""	""	""	""	"(2-(diphenylamino)-4-(4-methoxyphenyl)thiazol-5-yl)(phenyl)methanone"	""	""	"COc1ccc(cc1)c1nc(sc1C(=O)c1ccccc1)N(c1ccccc1)c1ccccc1"	"GCBYJNQEZBSRJO-UHFFFAOYSA-N"	"InChI=1S/C29H22N2O2S/c1-33-25-19-17-21(18-20-25)26-28(27(32)22-11-5-2-6-12-22)34-29(30-26)31(23-13-7-3-8-14-23)24-15-9-4-10-16-24/h2-20H,1H3"	"yes"	""	""
"9749"	"6E11"	""	"Synthetic organic"	""	""	""	""	"354702222"	"132427685"	""	""	""	""	""	""	""	"2-[4-(benzyloxy)phenyl]-2,5-dihydroxy-7-methoxy-3,4-dihydro-2H-1-benzopyran-4-one"	""	""	"COc1cc2OC(O)(CC(=O)c2c(c1)O)c1ccc(cc1)OCc1ccccc1"	"OUAZLWHOOTXVCE-UHFFFAOYSA-N"	"InChI=1S/C23H20O6/c1-27-18-11-19(24)22-20(25)13-23(26,29-21(22)12-18)16-7-9-17(10-8-16)28-14-15-5-3-2-4-6-15/h2-12,24,26H,13-14H2,1H3"	"yes"	""	""
"9878"	"6-Hydroxy-5,7-dimethoxyflavone"	""	"Natural product"	""	""	""	""	"363894172"	"14372618"	""	""	"CHEMBL464108"	""	""	""	""	""	""	"UFM-24|UFM24"	"COc1cc2oc(cc(=O)c2c(c1O)OC)c1ccccc1"	"YLSUKCVZCXUJBF-UHFFFAOYSA-N"	"InChI=1S/C17H14O5/c1-20-14-9-13-15(17(21-2)16(14)19)11(18)8-12(22-13)10-6-4-3-5-7-10/h3-9,19H,1-2H3"	"yes"	""	""
"5846"	"6-n-octylaminouracil"	""	"Synthetic organic"	""	""	""	""	"178102470"	"10354234"	""	""	""	""	""	""	""	"6-(octylamino)-1H-pyrimidine-2,4-dione"	""	"6-n-octyl aminouracil"	"CCCCCCCCNc1cc(=O)[nH]c(=O)[nH]1"	"PFSWASUQURIOOR-UHFFFAOYSA-N"	"InChI=1S/C12H21N3O2/c1-2-3-4-5-6-7-8-13-10-9-11(16)15-12(17)14-10/h9H,2-8H2,1H3,(H3,13,14,15,16,17)"	"yes"	""	""
"9025"	"852A"	""	"Synthetic organic"	""	""	""	""	"315661110"	"10309114"	""	""	"CHEMBL549344"	""	""	""	""	"N-[4-(4-amino-2-ethylimidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamide"	""	""	"CCc1nc2c(n1CCCCNS(=O)(=O)C)c1ccccc1nc2N"	"YZOQZEXYFLXNKA-UHFFFAOYSA-N"	"InChI=1S/C17H23N5O2S/c1-3-14-21-15-16(12-8-4-5-9-13(12)20-17(15)18)22(14)11-7-6-10-19-25(2,23)24/h4-5,8-9,19H,3,6-7,10-11H2,1-2H3,(H2,18,20)"	"yes"	""	""
"6592"	"A286982"	""	"Synthetic organic"	""	""	""	""	"178103205"	"9846729"	""	""	"CHEMBL19677"	""	""	""	""	"(E)-1-(4-acetylpiperazin-1-yl)-3-[3-nitro-4-(2-propan-2-ylphenyl)sulfanylphenyl]prop-2-en-1-one"	""	"A 286982|A-286982"	"O=C(N1CCN(CC1)C(=O)C)/C=C/c1ccc(c(c1)N(=O)=O)Sc1ccccc1C(C)C"	"HTGGAYLWTDOFDK-PKNBQFBNSA-N"	"InChI=1S/C24H27N3O4S/c1-17(2)20-6-4-5-7-22(20)32-23-10-8-19(16-21(23)27(30)31)9-11-24(29)26-14-12-25(13-15-26)18(3)28/h4-11,16-17H,12-15H2,1-3H3/b11-9+"	"yes"	""	""
"4118"	"A438079"	""	"Synthetic organic"	""	""	""	""	"178100940"	"11673921"	""	""	"CHEMBL377219"	""	""	""	""	"3-{[5-(2,3-dichlorophenyl)-1H-1,2,3,4-tetrazol-1-yl]methyl}pyridine"	""	"A 438079|A-438079"	"Clc1c(Cl)cccc1c1nnnn1Cc1cccnc1"	"MMPAULQSJLVKHP-UHFFFAOYSA-N"	"InChI=1S/C13H9Cl2N5/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9/h1-7H,8H2"	"yes"	""	""
"11154"	"AB928"	""	"Synthetic organic"	""	""	""	""	"434122214"	"135242184"	""	""	""	""	""	""	""	"3-[2-amino-6-[1-[[6-(2-hydroxypropan-2-yl)pyridin-2-yl]methyl]triazol-4-yl]pyrimidin-4-yl]-2-methylbenzonitrile"	""	"AB-928"	"N#Cc1cccc(c1C)c1nc(N)nc(c1)c1nnn(c1)Cc1cccc(n1)C(O)(C)C"	"BUXIAWLTBSXYSW-UHFFFAOYSA-N"	"InChI=1S/C23H22N8O/c1-14-15(11-24)6-4-8-17(14)18-10-19(28-22(25)27-18)20-13-31(30-29-20)12-16-7-5-9-21(26-16)23(2,3)32/h4-10,13,32H,12H2,1-3H3,(H2,25,27,28)"	"yes"	""	""
"6891"	"abatacept"	""	"Peptide"	"yes"	""	""	""	"178103473"	""	""	""	"CHEMBL1201823"	""	""	""	""	""	"abatacept"	"BMS-188667|CTLA4-IgG4m|Orencia®|RG-1046|RG-2077"	""	""	""	"yes"	""	""
"12917"	"ABBV-3373"	""	"Antibody"	""	""	""	""	"485206038"	""	""	""	""	""	""	""	""	""	""	"ADC 122"	""	""	""	"yes"	""	""
"14416"	"abdenoflast"	""	"Synthetic organic"	""	""	""	""	"523352208"	"156857536"	""	""	"CHEMBL5419019"	""	""	""	""	""	"abdenoflast"	"compound 13 [WO2021188450]"	"O=C(NC=1C2=C(C=C3C1CCC3)CCC2)NS(=O)(=O)C=4OC5=C(C4)CN6CCC5CC6"	"LQKIQSJLXCYGOX-UHFFFAOYSA-N"	"InChI=1S/C23H27N3O4S/c27-23(24-21-18-5-1-3-15(18)11-16-4-2-6-19(16)21)25-31(28,29)20-12-17-13-26-9-7-14(8-10-26)22(17)30-20/h11-12,14H,1-10,13H2,(H2,24,25,27)"	"yes"	""	""
"9326"	"abediterol"	""	"Synthetic organic"	""	""	""	""	"318164845"	"11962616"	""	""	"CHEMBL3039530"	""	""	""	""	"5-[(1R)-2-[6-(2,2-difluoro-2-phenylethoxy)hexylamino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one"	"abediterol"	"LAS-100977"	"O=c1ccc2c([nH]1)c(O)ccc2[C@H](CNCCCCCCOCC(c1ccccc1)(F)F)O"	"SFYAXIFVXBKRPK-QFIPXVFZSA-N"	"InChI=1S/C25H30F2N2O4/c26-25(27,18-8-4-3-5-9-18)17-33-15-7-2-1-6-14-28-16-22(31)19-10-12-21(30)24-20(19)11-13-23(32)29-24/h3-5,8-13,22,28,30-31H,1-2,6-7,14-17H2,(H,29,32)/t22-/m0/s1"	"yes"	""	""
"10013"	"AbGn-168H"	""	"Antibody"	""	""	""	""	"375973203"	""	""	""	""	""	""	""	""	""	""	"AbGn-168|neihulizumab"	""	""	""	"yes"	""	""
"9806"	"abrezekimab"	""	"Antibody"	""	""	""	""	"354702278"	""	""	""	""	""	""	""	""	""	"abrezekimab"	"CDP7766|UCB-4144|UCB4144|VR-942"	""	""	""	"yes"	""	""
"11531"	"abrilumab"	""	"Antibody"	""	""	""	""	"441604903"	""	""	""	""	""	""	""	""	""	"abrilumab"	"AMG 181|AMG-181|MEDI-7183|MEDI7183"	""	""	""	"yes"	""	""
"9991"	"abrocitinib"	""	"Synthetic organic"	"yes"	""	""	""	"374883878"	"78323835"	""	""	"CHEMBL3655081"	""	""	""	""	"N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide"	"abrocitinib"	"Cibinqo®|compound 25 [PMID: 29298069]|PF-04965842|PF04965842"	"CCCS(=O)(=O)N[C@@H]1C[C@@H](C1)N(c1ncnc2c1cc[nH]2)C"	"IUEWXNHSKRWHDY-PHIMTYICSA-N"	"InChI=1S/C14H21N5O2S/c1-3-6-22(20,21)18-10-7-11(8-10)19(2)14-12-4-5-15-13(12)16-9-17-14/h4-5,9-11,18H,3,6-8H2,1-2H3,(H,15,16,17)/t10-,11+"	"yes"	""	""
"10362"	"abscisic acid"	""	"Natural product"	""	""	""	""	"384403642"	"5375199"	""	""	"CHEMBL379808"	""	""	""	""	"(2Z,4E)-5-(1-hydroxy-2,6,6-trimethyl-4-oxo-1-cyclohex-2-enyl)-3-methylpenta-2,4-dienoic acid"	""	"(+/-)-(cis,trans)-abscisic acid|(+/-)-Abscisic acid|(RS)-Abscisic acid|ABA"	"OC(=O)/C=C(\C=C\C1(O)C(=CC(=O)CC1(C)C)C)/C"	"JLIDBLDQVAYHNE-LXGGSRJLSA-N"	"InChI=1S/C15H20O4/c1-10(7-13(17)18)5-6-15(19)11(2)8-12(16)9-14(15,3)4/h5-8,19H,9H2,1-4H3,(H,17,18)/b6-5+,10-7-"	"yes"	""	""
"8320"	"ABT-737"	""	"Synthetic organic"	""	""	""	""	"252166532"	"11228183"	""	""	"CHEMBL376408"	""	""	""	""	"4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-dimethylamino-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide"	""	"ABT 737|ABT737|compound 2 [PMID 17256834]"	"CN(CC[C@@H](Nc1ccc(cc1[N+](=O)[O-])S(=O)(=O)NC(=O)c1ccc(cc1)N1CCN(CC1)Cc1ccccc1c1ccc(cc1)Cl)CSc1ccccc1)C"	"HPLNQCPCUACXLM-PGUFJCEWSA-N"	"InChI=1S/C42H45ClN6O5S2/c1-46(2)23-22-35(30-55-37-9-4-3-5-10-37)44-40-21-20-38(28-41(40)49(51)52)56(53,54)45-42(50)32-14-18-36(19-15-32)48-26-24-47(25-27-48)29-33-8-6-7-11-39(33)31-12-16-34(43)17-13-31/h3-21,28,35,44H,22-27,29-30H2,1-2H3,(H,45,50)/t35-/m1/s1"	"yes"	""	""
"9177"	"AC430"	""	"Synthetic organic"	""	""	""	""	"315661260"	"56833309"	""	""	""	""	""	""	""	"(R)-(4-fluorophenyl)-[4-[(5-methyl-1H-pyrazol-3-yl)amino]quinazolin-2-yl]methanol"	""	"AC-430"	"Fc1ccc(cc1)[C@H](c1nc(Nc2n[nH]c(c2)C)c2c(n1)cccc2)O"	"DCRWIATZWHLIPN-QGZVFWFLSA-N"	"InChI=1S/C19H16FN5O/c1-11-10-16(25-24-11)22-18-14-4-2-3-5-15(14)21-19(23-18)17(26)12-6-8-13(20)9-7-12/h2-10,17,26H,1H3,(H2,21,22,23,24,25)/t17-/m1/s1"	"yes"	""	""
"8912"	"acalabrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"310264693"	"71226662"	""	""	""	""	""	""	""	"4-[8-amino-3-[(2S)-1-but-2-ynoylpyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl]-N-pyridin-2-ylbenzamide"	"acalabrutinib"	"ACP-196|Calquence®|Example 6 [US20140155385 A1]"	"CC#CC(=O)N1CCC[C@H]1c1nc(c2n1ccnc2N)c1ccc(cc1)C(=O)Nc1ccccn1"	"WDENQIQQYWYTPO-IBGZPJMESA-N"	"InChI=1S/C26H23N7O2/c1-2-6-21(34)32-15-5-7-19(32)25-31-22(23-24(27)29-14-16-33(23)25)17-9-11-18(12-10-17)26(35)30-20-8-3-4-13-28-20/h3-4,8-14,16,19H,5,7,15H2,1H3,(H2,27,29)(H,28,30,35)/t19-/m0/s1"	"yes"	""	""
"10060"	"Ac-SDKP"	""	"Peptide"	""	""	""	""	"375973248"	"65938"	""	""	""	""	""	""	""	"(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-4-hydroxy-4-oxobutanoyl]amino]-6-aminohexanoyl]pyrrolidine-2-carboxylic acid"	""	"goralatide|seraspenide"	"NCCCC[C@@H](C(=O)N1CCC[C@H]1C(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)CO)CC(=O)O"	"HJDRXEQUFWLOGJ-AJNGGQMLSA-N"	"InChI=1S/C20H33N5O9/c1-11(27)22-14(10-26)18(31)24-13(9-16(28)29)17(30)23-12(5-2-3-7-21)19(32)25-8-4-6-15(25)20(33)34/h12-15,26H,2-10,21H2,1H3,(H,22,27)(H,23,30)(H,24,31)(H,28,29)(H,33,34)/t12-,13-,14-,15-/m0/s1"	"yes"	""	""
"12326"	"ACT-1014-6470"	""	"Synthetic organic"	""	""	""	""	"479821117"	"142620206"	""	""	""	""	""	""	""	"2-(2,2-difluoropropyl)-5-[1-(2-fluoro-6-methylphenyl)piperidin-4-yl]-7-[[2-(trifluoromethyl)phenyl]methyl]-4H-pyrazolo[3,4-d]pyrimidin-6-one"	""	"example 172 [WO2019137927A1]|Ic-58"	"FC(Cn1nc2N(C(=O)N(Cc2c1)C1CCN(CC1)c1c(cccc1C)F)Cc1c(cccc1)C(F)(F)F)(C)F"	"YPWBQOVYMUEXJT-UHFFFAOYSA-N"	"InChI=1S/C28H29F6N5O/c1-18-6-5-9-23(29)24(18)36-12-10-21(11-13-36)38-16-20-14-37(17-27(2,30)31)35-25(20)39(26(38)40)15-19-7-3-4-8-22(19)28(32,33)34/h3-9,14,21H,10-13,15-17H2,1-2H3"	"yes"	""	""
"9511"	"ACT-389949"	""	"Synthetic organic"	""	""	""	""	"329968450"	"49834265"	""	""	""	""	""	""	""	"N-(2-{[4-(1,1-difluoroethyl)-1,3-oxazol-2-yl]methyl}-2H-1,2,3-triazol-4-yl)-2-methyl-5-(3-methylphenyl)-1,3-oxazole-4-carboxamide"	""	""	"Cc1cccc(c1)c1oc(nc1C(=O)Nc1cnn(n1)Cc1occ(n1)C(F)(F)C)C"	"PBTWPEDVIMHJEO-UHFFFAOYSA-N"	"InChI=1S/C20H18F2N6O3/c1-11-5-4-6-13(7-11)18-17(24-12(2)31-18)19(29)26-15-8-23-28(27-15)9-16-25-14(10-30-16)20(3,21)22/h4-8,10H,9H2,1-3H3,(H,26,27,29)"	"yes"	""	""
"12207"	"ACT-660602"	""	"Synthetic organic"	""	""	""	""	"472319327"	"87056189"	""	""	""	""	""	""	""	"2-(3,5-dimethyl-1,2,4-triazol-1-yl)-1-[(2R)-2-methyl-4-[2-(trifluoromethyl)-4-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-thiazol-5-yl]piperazin-1-yl]ethanone"	""	"ACT660602|compound 9j [PMID: 35947786]"	"C[C@@H]1CN(CCN1C(=O)Cn1nc(C)nc1C)c1c(c2cnc(C(F)(F)F)nc2)nc(C(F)(F)F)s1"	"JENUMEXEVAAAJX-SNVBAGLBSA-N"	"InChI=1S/C20H20F6N8OS/c1-10-8-32(4-5-33(10)14(35)9-34-12(3)29-11(2)31-34)16-15(30-18(36-16)20(24,25)26)13-6-27-17(28-7-13)19(21,22)23/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m1/s1"	"yes"	""	""
"12584"	"ACT-777991"	""	"Synthetic organic"	""	""	""	""	"479821374"	"121485701"	""	""	""	""	""	""	""	"1-[(2R)-2-(2-hydroxyethyl)-4-[2-(trifluoromethyl)-4-[2-(trifluoromethyl)pyrimidin-5-yl]-1,3-thiazol-5-yl]piperazin-1-yl]-2-(3-methyl-1,2,4-triazol-1-yl)ethanone"	""	"ACT777991|compound 8a [PMID: 36883854]"	"CC1=NN(C=N1)CC(=O)N2CCN(C[C@H]2CCO)C3=C(N=C(S3)C(F)(F)F)C4=CN=C(N=C4)C(F)(F)F"	"FDZFVXKCJKOSRC-CYBMUJFWSA-N"	"InChI=1S/C20H20F6N8O2S/c1-11-29-10-33(31-11)9-14(36)34-4-3-32(8-13(34)2-5-35)16-15(30-18(37-16)20(24,25)26)12-6-27-17(28-7-12)19(21,22)23/h6-7,10,13,35H,2-5,8-9H2,1H3/t13-/m1/s1"	"yes"	""	""
"3633"	"ACTH"	"Human"	"Peptide"	"yes"	""	""	""	"135651598"	"134611880"	"P01189"	"ENSG00000115138"	"CHEMBL1201610"	""	""	""	""	""	"corticotropin"	"Acthar®|adrenocorticotropic hormone (1-39)|corticotropin"	"NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccccc1)CCC(=O)O)CC(C)C)Cc1ccccc1)C)CCC(=O)O)C)CO)CCC(=O)O)CC(=O)O)CCC(=O)O)C)CC(=O)N)Cc1ccc(cc1)O)C(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](C(C)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)CNC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CO)N)Cc1ccc(cc1)O)CO)CCSC)CCC(=O)O)Cc1nc[nH]c1)Cc1ccccc1)CCCN=C(N)N)CCCCN)CCCCN)CCCCN)CCCN=C(N)N)CCCN=C(N)N"	"IDLFZVILOHSSID-OVLDLUHVSA-N"	"InChI=1S/C207H308N56O58S/c1-108(2)89-140(186(302)240-135(69-74-163(279)280)182(298)254-149(204(320)321)94-117-43-20-15-21-44-117)250-193(309)152-54-35-86-262(152)202(318)147(92-116-41-18-14-19-42-116)252-171(287)114(11)230-175(291)132(66-71-160(273)274)234-170(286)113(10)231-191(307)150(105-265)255-183(299)136(70-75-164(281)282)241-190(306)146(98-165(283)284)249-180(296)133(67-72-161(275)276)235-169(285)112(9)229-157(270)101-225-174(290)145(97-156(213)269)251-194(310)153-55-36-87-263(153)203(319)148(93-119-60-64-123(268)65-61-119)253-199(315)167(110(5)6)257-185(301)129(49-26-30-79-210)243-198(314)168(111(7)8)259-196(312)155-57-38-85-261(155)201(317)139(53-34-83-223-207(218)219)244-178(294)130(51-32-81-221-205(214)215)237-177(293)128(48-25-29-78-209)236-176(292)127(47-24-28-77-208)232-158(271)103-227-197(313)166(109(3)4)258-195(311)154-56-37-84-260(154)200(316)138(50-27-31-80-211)233-159(272)102-226-173(289)143(95-120-99-224-126-46-23-22-45-124(120)126)247-179(295)131(52-33-82-222-206(216)217)238-187(303)142(90-115-39-16-13-17-40-115)246-189(305)144(96-121-100-220-107-228-121)248-181(297)134(68-73-162(277)278)239-184(300)137(76-88-322-12)242-192(308)151(106-266)256-188(304)141(245-172(288)125(212)104-264)91-118-58-62-122(267)63-59-118/h13-23,39-46,58-65,99-100,107-114,125,127-155,166-168,224,264-268H,24-38,47-57,66-98,101-106,208-212H2,1-12H3,(H2,213,269)(H,220,228)(H,225,290)(H,226,289)(H,227,313)(H,229,270)(H,230,291)(H,231,307)(H,232,271)(H,233,272)(H,234,286)(H,235,285)(H,236,292)(H,237,293)(H,238,303)(H,239,300)(H,240,302)(H,241,306)(H,242,308)(H,243,314)(H,244,294)(H,245,288)(H,246,305)(H,247,295)(H,248,297)(H,249,296)(H,250,309)(H,251,310)(H,252,287)(H,253,315)(H,254,298)(H,255,299)(H,256,304)(H,257,301)(H,258,311)(H,259,312)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,283,284)(H,320,321)(H4,214,215,221)(H4,216,217,222)(H4,218,219,223)/t112-,113-,114-,125-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,152-,153-,154-,155-,166-,167-,168-/m0/s1"	"yes"	""	""
"9203"	"acumapimod"	""	"Synthetic organic"	""	""	""	""	"315661279"	"11338127"	""	""	""	""	""	""	""	"3-[5-amino-4-(3-cyanobenzoyl)pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide"	"acumapimod"	"BCT 197|BCT-197|BCT197|compound A [WO2013139809]"	"N#Cc1cccc(c1)C(=O)c1cnn(c1N)c1cc(ccc1C)C(=O)NC1CC1"	"VGUSQKZDZHAAEE-UHFFFAOYSA-N"	"InChI=1S/C22H19N5O2/c1-13-5-6-16(22(29)26-17-7-8-17)10-19(13)27-21(24)18(12-25-27)20(28)15-4-2-3-14(9-15)11-23/h2-6,9-10,12,17H,7-8,24H2,1H3,(H,26,29)"	"yes"	""	""
"4860"	"adalimumab"	""	"Antibody"	"yes"	""	""	""	"178101561"	""	""	""	""	""	""	""	""	""	"adalimumab"	"D2E7|Humira®"	""	""	""	"yes"	""	""
"479"	"(-)-adrenaline"	""	"Metabolite"	"yes"	""	""	""	"135651430"	"5816"	""	""	"CHEMBL679"	""	""	""	""	"4-[(1R)-1-hydroxy-2-methylaminoethyl]benzene-1,2-diol"	"epinephrine|racepinefrine"	"adrenalin|Auvi-Q®|Epipen®|l-adrenaline|L-epinephrine|levoepinephrine"	"CNC[C@@H](c1ccc(c(c1)O)O)O"	"UCTWMZQNUQWSLP-VIFPVBQESA-N"	"InChI=1S/C9H13NO3/c1-10-5-9(13)6-2-3-7(11)8(12)4-6/h2-4,9-13H,5H2,1H3/t9-/m0/s1"	"yes"	""	""
"683"	"adrenomedullin"	"Human"	"Peptide"	""	""	""	""	"135651602"	""	"P35318"	"ENSG00000148926"	""	""	""	""	""	""	""	"AM"	""	""	""	"yes"	""	""
"8985"	"adriforant"	""	"Synthetic organic"	""	""	""	""	"310264765"	"24745335"	""	""	"CHEMBL1915540"	""	""	""	""	"N'-(cyclopropylmethyl)-6-[(3R)-3-methylaminopyrrolidin-1-yl]pyrimidine-2,4-diamine"	"adriforant"	"PF 3893787|PF-03893787|ZPL-389|ZPL-3893787|ZPL389|ZPL3893787"	"CN[C@@H]1CCN(C1)c1cc(NCC2CC2)nc(n1)N"	"ISBHYKVAFKTATD-SNVBAGLBSA-N"	"InChI=1S/C13H22N6/c1-15-10-4-5-19(8-10)12-6-11(17-13(14)18-12)16-7-9-2-3-9/h6,9-10,15H,2-5,7-8H2,1H3,(H3,14,16,17,18)/t10-/m1/s1"	"yes"	""	""
"10192"	"ADU-S100"	""	"Synthetic organic"	""	""	""	""	"381118902"	"118989191"	""	""	""	""	""	""	""	""	""	"dithio-(Rp,Rp)-[cyclic[A(2',5')pA(3',5')p]]|MIW815|ML RR-S2 CDA|S100"	"OC1[C@H]2COP(=O)(S)O[C@@H]3[C@@H](COP(=S)(O[C@H]1[C@@H](O2)n1cnc2c1ncnc2N)O)O[C@H]([C@@H]3O)n1cnc2c1ncnc2N"	"IZJJFUQKKZFVLH-LTKSHMRXSA-N"	"InChI=1S/C20H24N10O10P2S2/c21-15-9-17(25-3-23-15)29(5-27-9)19-12(32)13-8(38-19)2-36-42(34,44)40-14-11(31)7(1-35-41(33,43)39-13)37-20(14)30-6-28-10-16(22)24-4-26-18(10)30/h3-8,11-14,19-20,31-32H,1-2H2,(H,33,43)(H,34,44)(H2,21,23,25)(H2,22,24,26)/t7-,8-,11?,12-,13-,14-,19-,20-,41?,42?/m1/s1"	"yes"	""	""
"4861"	"AF12198"	""	"Peptide"	""	""	""	""	"178101562"	"16135237"	""	""	""	""	""	""	""	""	""	"AF 12198|AF-12198"	""	""	""	"yes"	""	""
"10067"	"AFM13"	""	"Antibody"	""	""	""	""	"375973255"	""	""	""	""	""	""	""	""	""	""	"AFM 13|AFM-13"	""	""	""	"yes"	""	""
"9843"	"agatolimod"	""	"Synthetic organic"	""	""	""	""	"363894137"	"56841790"	""	""	""	""	""	""	""	""	"agatolimod"	"CpG 7909|CpG7909|PF 3512676|PF-3512676|ProMune|VaxImmune"	"OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1OP(=S)(OCC1OC(CC1O)n1cc(C)c(=O)[nH]c1=O)O)n1cc(C)c(=O)[nH]c1=O)O)n1cnc2c1nc(N)[nH]c2=O)O)n1ccc(nc1=O)N)O)n1cc(C)c(=O)[nH]c1=O)O)n1cnc2c1nc(N)[nH]c2=O)O)n1cc(C)c(nc1=O)N)O)n1cc(C)c(nc1=O)N)O)n1cc(C)c(nc1=O)N)O)n1cc(C)c(nc1=O)N)O)n1cnc2c1nc(N)[nH]c2=O)O)n1ccc(nc1=O)N)O)n1cc(C)c(=O)[nH]c1=O)O)n1cnc2c1nc(N)[nH]c2=O)O)n1cc(C)c(=O)[nH]c1=O)O)n1cc(C)c(=O)[nH]c1=O)O)n1cc(C)c(nc1=O)N)O)n1cc(C)c(nc1=O)N)O)n1cnc(c1C)C(=O)NC(=C)N)O)n1ccc(nc1=O)N)O)n1cc(C)c(=O)[nH]c1=O)O)n1cnc2c1nc(N)[nH]c2=O)O)n1ccc(nc1=O)N)O)n1cc(C)c(=O)[nH]c1=O"	"GUVMFDICMFQHSZ-UHFFFAOYSA-N"	""	"yes"	""	""
"13646"	"AGU654"	""	"Synthetic organic"	""	""	""	""	"504705465"	"171637720"	""	""	""	""	""	""	""	"2-chloro-N-[4-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]phenyl]-5-[[[1-(trifluoromethyl)cyclopropanecarbonyl]amino]methyl]benzamide"	""	"AGU-654|compound 44 [PMID: 39622054]"	"ClC1=C(C(=O)NC2=CC=C(C=C2)C3=NC4=C(N3)C=CC(=C4)C(F)(F)F)C=C(C=C1)CNC(=O)C5(CC5)C(F)(F)F"	"QLJJIKAYPMNUEM-UHFFFAOYSA-N"	"InChI=1S/C27H19ClF6N4O2/c28-19-7-1-14(13-35-24(40)25(9-10-25)27(32,33)34)11-18(19)23(39)36-17-5-2-15(3-6-17)22-37-20-8-4-16(26(29,30)31)12-21(20)38-22/h1-8,11-12H,9-10,13H2,(H,35,40)(H,36,39)(H,37,38)"	"yes"	""	""
"9899"	"AH10-7"	""	"Synthetic organic"	""	""	""	""	"363894193"	"133081970"	""	""	""	""	""	""	""	"N-[(2S,3R)-3-hydroxy-1-{[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-{[(4-phenylbut-1-en-2-yl)oxy]methyl}oxan-2-yl]oxy}octadecan-2-yl]hexacosanamide"	""	""	"CCCCCCCCCCCCCCCCCCCCCCCCCC(=O)N[C@H]([C@@H](CCCCCCCCCCCCCCC)O)CO[C@H]1O[C@H](COC(=C)CCc2ccccc2)[C@@H]([C@@H]([C@H]1O)O)O"	"AACQUTZHAXVZEB-MMSUBXCOSA-N"	"InChI=1S/C60H109NO8/c1-4-6-8-10-12-14-16-18-19-20-21-22-23-24-25-26-27-29-31-33-35-37-42-46-56(63)61-53(54(62)45-41-36-34-32-30-28-17-15-13-11-9-7-5-2)49-68-60-59(66)58(65)57(64)55(69-60)50-67-51(3)47-48-52-43-39-38-40-44-52/h38-40,43-44,53-55,57-60,62,64-66H,3-37,41-42,45-50H2,1-2H3,(H,61,63)/t53-,54+,55+,57-,58-,59+,60-/m0/s1"	"yes"	""	""
"1896"	"AH6809"	""	"Synthetic organic"	""	""	""	""	"135649910"	"119461"	""	""	"CHEMBL1317823"	""	""	""	""	"9-oxo-6-propan-2-yloxyxanthene-2-carboxylic acid"	""	"AH 6809|AH-6809"	"CC(Oc1ccc2c(c1)oc1c(c2=O)cc(cc1)C(=O)O)C"	"AQFFXPQJLZFABJ-UHFFFAOYSA-N"	"InChI=1S/C17H14O5/c1-9(2)21-11-4-5-12-15(8-11)22-14-6-3-10(17(19)20)7-13(14)16(12)18/h3-9H,1-2H3,(H,19,20)"	"yes"	""	""
"13090"	"AJ2-30"	""	"Synthetic organic"	""	""	""	""	"491299872"	"163902400"	""	""	""	""	""	""	""	"N-[(9-ethylcarbazol-3-yl)methyl]-1-methylbenzimidazol-2-amine"	""	"compound 4 [PMID: 38191941]"	"CCN1C2=C(C=CC=C2)C3=C1C=CC(CNC4=NC5=C(C=CC=C5)N4C)=C3"	"QKZNLVHPKAXDOL-UHFFFAOYSA-N"	"InChI=1S/C23H22N4/c1-3-27-20-10-6-4-8-17(20)18-14-16(12-13-21(18)27)15-24-23-25-19-9-5-7-11-22(19)26(23)2/h4-14H,3,15H2,1-2H3,(H,24,25)"	"yes"	""	""
"9219"	"AL-78898A"	""	"Peptide"	""	""	""	""	"315661295"	""	""	""	""	""	""	""	""	""	""	"4(1MeW)|POT-4"	""	""	""	"yes"	""	""
"7587"	"alcaftadine"	""	"Synthetic organic"	"yes"	""	""	""	"223365922"	"19371515"	""	""	"CHEMBL1201747"	""	""	""	""	"11-(1-methylpiperidin-4-ylidene)-5,6-dihydroimidazo[2,3-b][3]benzazepine-3-carbaldehyde"	"alcaftadine"	"Lastacaft®|R-89674"	"O=Cc1cnc2n1CCc1c(C2=C2CCN(CC2)C)cccc1"	"MWTBKTRZPHJQLH-UHFFFAOYSA-N"	"InChI=1S/C19H21N3O/c1-21-9-6-15(7-10-21)18-17-5-3-2-4-14(17)8-11-22-16(13-23)12-20-19(18)22/h2-5,12-13H,6-11H2,1H3"	"yes"	""	""
"6787"	"alefacept"	""	"Peptide"	"yes"	"yes"	""	""	"178103393"	""	""	""	"CHEMBL1201571"	""	""	""	""	""	"alefacept"	"Amevive®|BG 9273|BG 9712|BG-9273|BG-9712|Lfa3Tip"	""	""	""	"yes"	""	""
"6770"	"alemtuzumab"	""	"Antibody"	"yes"	""	""	""	"178103376"	""	""	""	""	""	""	""	""	""	"alemtuzumab"	"campath 1H|Campath®|campath-1H|Lemtrada®"	""	""	""	"yes"	""	""
"7237"	"alimemazine"	""	"Synthetic organic"	"yes"	""	""	""	"178103811"	"5574"	""	""	"CHEMBL829"	""	""	""	""	"dimethyl[2-methyl-3-(10H-phenothiazin-10-yl)propyl]amine"	"alimemazine"	"Nedeltran®|trimeprazine"	"CN(CC(CN1c2ccccc2Sc2c1cccc2)C)C"	"ZZHLYYDVIOPZBE-UHFFFAOYSA-N"	"InChI=1S/C18H22N2S/c1-14(12-19(2)3)13-20-15-8-4-6-10-17(15)21-18-11-7-5-9-16(18)20/h4-11,14H,12-13H2,1-3H3"	"yes"	""	""
"9781"	"α-NETA"	""	"Synthetic organic"	""	""	""	""	"354702254"	"1518"	""	""	"CHEMBL1358898"	""	""	""	""	"trimethyl-(3-naphthalen-1-yl-3-oxopropyl)azanium"	""	""	"O=C(c1cccc2c1cccc2)CC[N+](C)(C)C"	"WZJKPXZLQTXALB-UHFFFAOYSA-N"	"InChI=1S/C16H20NO/c1-17(2,3)12-11-16(18)15-10-6-8-13-7-4-5-9-14(13)15/h4-10H,11-12H2,1-3H3/q+1"	"yes"	""	""
"9615"	"ALT-803"	""	"Antibody"	""	""	""	""	"340590245"	""	""	""	""	""	""	""	""	""	""	"IL-15 N72D:IL-15RαSu/Fc|IL-15SA|N-803"	""	""	""	"yes"	""	""
"6476"	"alvelestat"	""	"Synthetic organic"	""	""	""	""	"178103090"	"46861623"	""	""	""	""	""	""	""	"N-[(5-methanesulfonylpyridin-2-yl)methyl]-6-methyl-5-(1-methyl-1H-pyrazol-5-yl)-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide"	"alvelestat"	"AZD 9668|AZD-9668|AZD9668|KB-105160"	"O=C(c1cc(c(n(c1=O)c1cccc(c1)C(F)(F)F)C)c1ccnn1C)NCc1ccc(cn1)S(=O)(=O)C"	"QNQZWEGMKJBHEM-UHFFFAOYSA-N"	"InChI=1S/C25H22F3N5O4S/c1-15-20(22-9-10-31-32(22)2)12-21(23(34)30-13-17-7-8-19(14-29-17)38(3,36)37)24(35)33(15)18-6-4-5-16(11-18)25(26,27)28/h4-12,14H,13H2,1-3H3,(H,30,34)"	"yes"	""	""
"10170"	"AM-461"	""	"Synthetic organic"	""	""	""	""	"381118880"	"44600763"	""	""	""	""	""	""	""	"2-[3-[2-(tert-butylsulfanylmethyl)-4-(2,2-dimethylpropanoylamino)phenoxy]-4-methoxyphenyl]acetic acid"	""	"AM461|Compound 1 [WO2011085033]"	"COc1ccc(cc1Oc1ccc(cc1CSC(C)(C)C)NC(=O)C(C)(C)C)CC(=O)O"	"SDHFXINHZHARIB-UHFFFAOYSA-N"	"InChI=1S/C25H33NO5S/c1-24(2,3)23(29)26-18-9-11-19(17(14-18)15-32-25(4,5)6)31-21-12-16(13-22(27)28)8-10-20(21)30-7/h8-12,14H,13,15H2,1-7H3,(H,26,29)(H,27,28)"	"yes"	""	""
"10119"	"AM-6120"	""	"Peptide"	""	""	""	""	"381118829"	""	""	""	""	""	""	""	""	""	""	"AM6120|peptide 41 [PMID: 30346167]"	""	""	""	"yes"	""	""
"7060"	"amcinonide"	""	"Synthetic organic"	"yes"	""	""	""	"178103639"	"443958"	""	""	"CHEMBL1200732"	""	""	""	""	""	"amcinonide"	"CL-34699|Cyclocort®"	"CC(=O)OCC(=O)[C@@]12OC3(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1CCC1=CC(=O)C=C[C@]21C)F)CCCC3"	"ILKJAFIWWBXGDU-MOGDOJJUSA-N"	"InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1"	"yes"	""	""
"13384"	"amelenodor"	""	"Synthetic organic"	""	""	""	""	"496703354"	"146651362"	""	""	"CHEMBL5095087"	""	""	""	""	"2-[3,5-bis[(6-methylpyridin-2-yl)oxy]phenoxy]-6-methylpyridine"	"amelenodor"	"example 2 [WO2020010132A1]|NX-13|NX13"	"CC1=NC(=CC=C1)OC2=CC(=CC(=C2)OC3=CC=CC(=N3)C)OC4=CC=CC(=N4)C"	"OPUQKVNCXCWRLR-UHFFFAOYSA-N"	"InChI=1S/C24H21N3O3/c1-16-7-4-10-22(25-16)28-19-13-20(29-23-11-5-8-17(2)26-23)15-21(14-19)30-24-12-6-9-18(3)27-24/h4-15H,1-3H3"	"yes"	""	""
"8463"	"amelubant"	""	"Synthetic organic"	""	""	""	""	"252166673"	"60096302"	""	""	""	""	""	""	""	"ethyl (NZ)-N-[amino-[4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]phenyl]methylidene]carbamate"	"amelubant"	"BIIL 284|BIIL-284"	"CCOC(=O)NC(=N)c1ccc(cc1)OCc1cccc(c1)COc1ccc(cc1)C(c1ccc(cc1)O)(C)C"	"SBVYURPQULDJTI-UHFFFAOYSA-N"	"InChI=1S/C33H34N2O5/c1-4-38-32(37)35-31(34)25-8-16-29(17-9-25)39-21-23-6-5-7-24(20-23)22-40-30-18-12-27(13-19-30)33(2,3)26-10-14-28(36)15-11-26/h5-20,36H,4,21-22H2,1-3H3,(H2,34,35,37)"	"yes"	""	""
"8917"	"AMG319"	""	"Synthetic organic"	""	""	""	""	"310264698"	"68947304"	""	""	""	""	""	""	""	"N-[(1S)-1-(7-fluoro-2-pyridin-2-ylquinolin-3-yl)ethyl]-7H-purin-6-amine"	""	"AMG 319|AMG-319"	"Fc1ccc2c(c1)nc(c(c2)[C@@H](Nc1ncnc2c1[nH]cn2)C)c1ccccn1"	"KWRYMZHCQIOOEB-LBPRGKRZSA-N"	"InChI=1S/C21H16FN7/c1-12(28-21-19-20(25-10-24-19)26-11-27-21)15-8-13-5-6-14(22)9-17(13)29-18(15)16-4-2-3-7-23-16/h2-12H,1H3,(H2,24,25,26,27,28)/t12-/m0/s1"	"yes"	""	""
"13071"	"AMG487"	""	"Synthetic organic"	""	""	""	""	"491299853"	"10282265"	""	""	""	""	""	""	""	"N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-N-(pyridin-3-ylmethyl)-2-[4-(trifluoromethoxy)phenyl]acetamide"	""	"AMG 487|AMG-487|compound 47 [PMID: 17448658]"	"CCOC1=CC=C(C=C1)N2C(=O)C3=C(N=CC=C3)N=C2C(C)N(CC4=CN=CC=C4)C(=O)CC5=CC=C(C=C5)OC(F)(F)F"	"WQTKNBPCJKRYPA-UHFFFAOYSA-N"	"InChI=1S/C32H28F3N5O4/c1-3-43-25-14-10-24(11-15-25)40-30(38-29-27(31(40)42)7-5-17-37-29)21(2)39(20-23-6-4-16-36-19-23)28(41)18-22-8-12-26(13-9-22)44-32(33,34)35/h4-17,19,21H,3,18,20H2,1-2H3"	"yes"	""	""
"9106"	"AMG820"	""	"Antibody"	""	""	""	""	"315661191"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"10051"	"aminopyridine 2"	""	"Synthetic organic"	""	""	""	""	"375973239"	"134813904"	""	""	""	""	""	""	""	"1-((6-aminopyridin-3-yl)methyl)-3-(4-bromophenyl)urea"	""	""	"O=C(Nc1ccc(cc1)Br)NCc1ccc(nc1)N"	"NNDXEGUWCFIHTD-UHFFFAOYSA-N"	"InChI=1S/C13H13BrN4O/c14-10-2-4-11(5-3-10)18-13(19)17-8-9-1-6-12(15)16-7-9/h1-7H,8H2,(H2,15,16)(H2,17,18,19)"	"yes"	""	""
"9319"	"amiselimod"	""	"Synthetic organic"	""	""	""	""	"318164838"	"16129483"	""	""	""	""	""	""	""	"2-amino-2-[2-[4-heptoxy-3-(trifluoromethyl)phenyl]ethyl]propane-1,3-diol"	"amiselimod"	"Example 1 [US20090137530]|MT-1303|MT1303"	"CCCCCCCOc1ccc(cc1C(F)(F)F)CCC(CO)(CO)N"	"JVCPIJKPAKAIIP-UHFFFAOYSA-N"	"InChI=1S/C19H30F3NO3/c1-2-3-4-5-6-11-26-17-8-7-15(12-16(17)19(20,21)22)9-10-18(23,13-24)14-25/h7-8,12,24-25H,2-6,9-11,13-14,23H2,1H3"	"yes"	""	""
"9491"	"amiselimod phosphate"	""	"Synthetic organic"	""	""	""	""	"329968431"	"57704582"	""	""	""	""	""	""	""	"[(2R)-2-amino-4-[4-heptoxy-3-(trifluoromethyl)phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate"	""	"amiselimod-P|MT-1303-P"	"CCCCCCCOc1ccc(cc1C(F)(F)F)CC[C@](COP(=O)(O)O)(CO)N"	"OFRUGVQKZMGHHH-GOSISDBHSA-N"	"InChI=1S/C19H31F3NO6P/c1-2-3-4-5-6-11-28-17-8-7-15(12-16(17)19(20,21)22)9-10-18(23,13-24)14-29-30(25,26)27/h7-8,12,24H,2-6,9-11,13-14,23H2,1H3,(H2,25,26,27)/t18-/m1/s1"	"yes"	""	""
"7113"	"amlexanox"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178103690"	"2161"	""	""	"CHEMBL1096"	""	""	""	""	"2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid"	"amlexanox"	"AA-673|Amlexanox®|Aphthasol®|CHX-3673"	"CC(c1ccc2c(c1)c(=O)c1c(o2)nc(c(c1)C(=O)O)N)C"	"SGRYPYWGNKJSDL-UHFFFAOYSA-N"	"InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)"	"yes"	""	""
"4864"	"amphiregulin"	"Human"	"Peptide"	""	""	""	""	"178101565"	""	"P15514"	"ENSG00000109321"	""	""	""	""	""	""	""	"colorectal cell-derived growth factor (CRDGF)"	""	""	""	"yes"	""	""
"11645"	"AMT-101"	""	"Peptide"	""	""	""	""	"442878671"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"12789"	"AMY109"	""	"Antibody"	""	""	""	""	"483123337"	""	""	""	""	""	""	""	""	""	""	"AMY-109|H1009/L395-F1974m"	""	""	""	"yes"	""	""
"6972"	"anakinra"	""	"Peptide"	"yes"	""	""	""	"178103551"	""	""	""	"CHEMBL1201570"	""	""	""	""	""	"anakinra"	"antril|Kineret®"	""	""	""	"yes"	""	""
"9947"	"anatumomab mafenatox"	""	"Antibody"	""	""	""	""	"374883834"	""	""	""	"CHEMBL2108248"	""	""	""	""	""	"anatumomab mafenatox"	"5T4FabV13SEA<sub>D227A</sub>|ABR 214936|ABR-214936|ABR214936|pMB125|PNU 214936|PNU-214936|PNU214936|TTS-CD2"	""	""	""	"yes"	""	""
"804"	"ancriviroc"	""	"Synthetic organic"	""	""	""	""	"135649944"	"9574343"	""	""	"CHEMBL78535"	""	""	""	""	"[4-[4-[(Z)-C-(4-bromophenyl)-N-ethoxycarbonimidoyl]piperidin-1-yl]-4-methylpiperidin-1-yl]-(2,4-dimethyl-1-oxidopyridin-1-ium-3-yl)methanone"	"ancriviroc"	"SCH 351125|SCH-351125|SCH-C"	"CCO/N=C(\c1ccc(cc1)Br)/C1CCN(CC1)C1(C)CCN(CC1)C(=O)c1c(C)cc[n+](c1C)[O-]"	"ZGDKVKUWTCGYOA-URGPHPNLSA-N"	"InChI=1S/C28H37BrN4O3/c1-5-36-30-26(22-6-8-24(29)9-7-22)23-11-15-32(16-12-23)28(4)13-18-31(19-14-28)27(34)25-20(2)10-17-33(35)21(25)3/h6-10,17,23H,5,11-16,18-19H2,1-4H3/b30-26+"	"yes"	""	""
"9510"	"andecaliximab"	""	"Antibody"	""	""	""	""	"329968449"	""	""	""	""	""	""	""	""	""	"andecaliximab"	"GS-5745|GS5745"	""	""	""	"yes"	""	""
"9675"	"andrographolide"	""	"Synthetic organic"	""	""	""	""	"348353634"	"5318517"	""	""	""	""	""	""	""	"(3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxyoxolan-2-one"	""	""	"OC[C@]1(C)[C@H](O)CC[C@@]2([C@@H]1CCC(=C)[C@H]2C/C=C/1\[C@H](O)COC1=O)C"	"BOJKULTULYSRAS-OTESTREVSA-N"	"InChI=1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1"	"yes"	""	""
"8258"	"anifrolumab"	""	"Antibody"	"yes"	""	""	""	"249565938"	""	""	""	""	""	""	""	""	""	"anifrolumab"	"anifrolumab-fnia|MDX-1333|MEDI-546|Saphnelo&reg;"	""	""	""	"yes"	""	""
"13274"	"anti-FXII nanobody N4-38"	""	"Antibody"	""	""	""	""	"491300056"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"1860"	"apafant"	""	"Synthetic organic"	""	""	""	""	"135649947"	"65889"	""	""	"CHEMBL280164"	""	""	""	""	"3-[7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetraazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-4-yl]-1-(morpholin-4-yl)propan-1-one"	"apafant"	"WEB 2086 BS|WEB-2086"	"O=C(N1CCOCC1)CCc1sc2c(c1)C(=NCc1n2c(C)nn1)c1ccccc1Cl"	"JGPJQFOROWSRRS-UHFFFAOYSA-N"	"InChI=1S/C22H22ClN5O2S/c1-14-25-26-19-13-24-21(16-4-2-3-5-18(16)23)17-12-15(31-22(17)28(14)19)6-7-20(29)27-8-10-30-11-9-27/h2-5,12H,6-11,13H2,1H3"	"yes"	""	""
"13869"	"APB-R3"	""	"Peptide"	""	""	""	""	"513757554"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9859"	"apilimod"	""	"Synthetic organic"	""	""	""	""	"363894153"	"10173277"	""	""	""	""	""	""	""	"N-[(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine"	"apilimod"	"LAM-002A (apilimod dimesylate)|LAM002A|STA 5326|STA-5326|STA5326"	"Cc1cccc(c1)/C=N/Nc1nc(OCCc2ccccn2)nc(c1)N1CCOCC1"	"HSKAZIJJKRAJAV-KOEQRZSOSA-N"	"InChI=1S/C23H26N6O2/c1-18-5-4-6-19(15-18)17-25-28-21-16-22(29-10-13-30-14-11-29)27-23(26-21)31-12-8-20-7-2-3-9-24-20/h2-7,9,15-17H,8,10-14H2,1H3,(H,26,27,28)/b25-17+"	"yes"	""	""
"6482"	"apratastat"	""	"Synthetic organic"	""	""	""	""	"178103096"	"11452716"	""	""	"CHEMBL206815"	""	""	""	""	"(3S)-N-hydroxy-4-[4-(4-hydroxybut-2-ynoxy)phenyl]sulfonyl-2,2-dimethylthiomorpholine-3-carboxamide"	"apratastat"	"compound 5h [PMID: 16426848]|TMI-05|TMI005"	"OCC#CCOc1ccc(cc1)S(=O)(=O)N1CCSC([C@@H]1C(=O)NO)(C)C"	"MAVDNGWEBZTACC-HNNXBMFYSA-N"	"InChI=1S/C17H22N2O6S2/c1-17(2)15(16(21)18-22)19(9-12-26-17)27(23,24)14-7-5-13(6-8-14)25-11-4-3-10-20/h5-8,15,20,22H,9-12H2,1-2H3,(H,18,21)/t15-/m0/s1"	"yes"	""	""
"7372"	"apremilast"	""	"Synthetic organic"	"yes"	""	""	""	"178103944"	"11561674"	""	""	"CHEMBL514800"	""	""	""	""	"N-[2-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-1,3-dioxoisoindol-4-yl]acetamide"	"apremilast"	"CC-10004|Otezla&reg;"	"CCOc1cc(ccc1OC)[C@H](N1C(=O)c2c(C1=O)c(ccc2)NC(=O)C)CS(=O)(=O)C"	"IMOZEMNVLZVGJZ-QGZVFWFLSA-N"	"InChI=1S/C22H24N2O7S/c1-5-31-19-11-14(9-10-18(19)30-3)17(12-32(4,28)29)24-21(26)15-7-6-8-16(23-13(2)25)20(15)22(24)27/h6-11,17H,5,12H2,1-4H3,(H,23,25)/t17-/m1/s1"	"yes"	""	""
"5068"	"APRIL"	"Human"	"Peptide"	""	""	""	""	"178101761"	""	"O75888"	"ENSG00000161955"	""	""	""	""	""	""	""	"A proliferation-inducing ligand|TALL2|TNF- and APOL-related leukocyte expressed ligand 2|TNF-related death ligand 1|TRDL-1|ZTNF2"	""	""	""	"yes"	""	""
"13556"	"Apta-1"	""	"Nucleic acid"	""	""	""	""	"500839966"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	"yes"	""
"13112"	"AR-9281"	""	"Synthetic organic"	""	""	""	""	"491299894"	"12000797"	""	""	"CHEMBL436774"	""	""	""	""	"1-(1-acetylpiperidin-4-yl)-3-(1-adamantyl)urea"	""	"AR9281|compound 14a [PMID: 21211973]"	"CC(=O)N1CCC(CC1)NC(=O)NC23CC4CC(C2)CC(C4)C3"	"HUDQLWBKJOMXSZ-UHFFFAOYSA-N"	"InChI=1S/C18H29N3O2/c1-12(22)21-4-2-16(3-5-21)19-17(23)20-18-9-13-6-14(10-18)8-15(7-13)11-18/h13-16H,2-11H2,1H3,(H2,19,20,23)"	"yes"	""	""
"7479"	"arformoterol"	""	"Synthetic organic"	"yes"	""	""	""	"187051782"	"3083544"	""	""	"CHEMBL1363"	""	""	""	""	"N-[2-hydroxy-5-[(1R)-1-hydroxy-2-[[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino]ethyl]phenyl]formamide"	""	"(-)-Formoterol|(R,R)-Formoterol|Brovana&reg;|YM-08316"	"O=CNc1cc(ccc1O)[C@H](CN[C@@H](Cc1ccc(cc1)OC)C)O"	"BPZSYCZIITTYBL-YJYMSZOUSA-N"	"InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)/t13-,19+/m1/s1"	"yes"	""	""
"10120"	"ARN19702"	""	"Synthetic organic"	""	""	""	""	"381118830"	"132145761"	""	""	""	""	""	""	""	"(2-ethylsulfonylphenyl)-[(2S)-4-(6-fluoro-1,3-benzothiazol-2-yl)-2-methyl-piperazin-1-yl]methanone"	""	"ARN-19702|compound 8 [PMID: 27404798]"	"CCS(=O)(=O)c1ccccc1C(=O)N1CCN(C[C@@H]1C)c1sc2c(n1)ccc(c2)F"	"UKQOLPNYRVPCBM-AWEZNQCLSA-N"	"InChI=1S/C21H22FN3O3S2/c1-3-30(27,28)19-7-5-4-6-16(19)20(26)25-11-10-24(13-14(25)2)21-23-17-9-8-15(22)12-18(17)29-21/h4-9,12,14H,3,10-11,13H2,1-2H3/t14-/m0/s1"	"yes"	""	""
"9178"	"ARN726"	""	"Synthetic organic"	""	""	""	""	"315661261"	"78319072"	""	""	""	""	""	""	""	"4-cyclohexylbutyl N-[(3S)-2-oxoazetidin-3-yl]carbamate"	""	"ARN-726|compound 6 [PMID: 25874594]"	"O=C(N[C@H]1CNC1=O)OCCCCC1CCCCC1"	"FNLUJRBWJBUJTC-LBPRGKRZSA-N"	"InChI=1S/C14H24N2O3/c17-13-12(10-15-13)16-14(18)19-9-5-4-8-11-6-2-1-3-7-11/h11-12H,1-10H2,(H,15,17)(H,16,18)/t12-/m0/s1"	"yes"	""	""
"1221"	"arpromidine"	""	"Synthetic organic"	""	""	""	""	"135649957"	"65895"	""	""	"CHEMBL293802"	""	""	""	""	"1-[3-(4-fluorophenyl)-3-pyridin-2-ylpropyl]-2-[3-(3H-imidazol-4-yl)propyl]guanidine"	"arpromidine"	"ARP"	"NC(=NCCCc1[nH]cnc1)NCCC(c1ccccn1)c1ccc(cc1)F"	"KZZIVOLMJPSDEP-UHFFFAOYSA-N"	"InChI=1S/C21H25FN6/c22-17-8-6-16(7-9-17)19(20-5-1-2-11-25-20)10-13-27-21(23)26-12-3-4-18-14-24-15-28-18/h1-2,5-9,11,14-15,19H,3-4,10,12-13H2,(H,24,28)(H3,23,26,27)"	"yes"	""	""
"11095"	"ARRY-371797"	""	"Synthetic organic"	""	""	""	""	"434122156"	"46883775"	""	""	"CHEMBL1088750"	""	""	""	""	"-(2,4-difluorophenoxy)-N-[2-(dimethylamino)ethyl]-1-(2-methylpropyl)indazole-6-carboxamide"	""	"ARRY-797|ARRY371797|ARRY797|compound 7 [PMID: 19950901]"	"CN(CCNC(=O)c1cc2c(cc1Oc1ccc(cc1F)F)cnn2CC(C)C)C"	"IFGWYHGYNVGVRB-UHFFFAOYSA-N"	"InChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)"	"yes"	""	""
"9108"	"ARRY-382"	""	"Synthetic organic"	""	""	""	""	"315661193"	"67259771"	""	""	"CHEMBL3644252"	""	""	""	""	"N-[3-cyclopropyl-1-[(6-methylpyridin-2-yl)methyl]indazol-4-yl]-7-[2-(4-methylpiperazin-1-yl)ethoxy]imidazo[1,2-a]pyridine-3-carboxamide"	""	"ARRY 382|ARRY382|c-Fms-IN-12|PF-07265804|PF07265804"	"CN1CCN(CCOC2=CC3=NC=C(N3C=C2)C(=O)NC4=CC=CC5=C4C(=NN5CC6=NC(C)=CC=C6)C7CC7)CC1"	"JUPOTOIJLKDAPF-UHFFFAOYSA-N"	"InChI=1S/C32H36N8O2/c1-22-5-3-6-24(34-22)21-40-27-8-4-7-26(30(27)31(36-40)23-9-10-23)35-32(41)28-20-33-29-19-25(11-12-39(28)29)42-18-17-38-15-13-37(2)14-16-38/h3-8,11-12,19-20,23H,9-10,13-18,21H2,1-2H3,(H,35,41)"	"yes"	""	""
"10179"	"ARRY-502"	""	"Synthetic organic"	""	""	""	""	"381118889"	"131633366"	""	""	""	""	""	""	""	""	""	"ARRY502|example 237, enantiomer 1 [WO2009158426A1]"	"COc1cc(Cl)ccc1CCNC(=O)c1ccc(cc1)Oc1cc2OCC[C@@H](c2cc1Cl)C(=O)O"	"QIDYUNXQPQEJEC-IBGZPJMESA-N"	"InChI=1S/C26H23Cl2NO6/c1-33-22-12-17(27)5-2-15(22)8-10-29-25(30)16-3-6-18(7-4-16)35-24-14-23-20(13-21(24)28)19(26(31)32)9-11-34-23/h2-7,12-14,19H,8-11H2,1H3,(H,29,30)(H,31,32)/t19-/m0/s1"	"yes"	""	""
"437"	"AS101"	""	"Synthetic organic"	""	""	""	""	"135649959"	"135476605"	""	""	""	""	""	""	""	"[(5Z)-5-(2,6-dioxo-1,3-dipropylpurin-8-ylidene)-1-methyl-2H-pyrazol-3-yl] 2-[(3,4-dimethoxyphenyl)amino]acetate"	""	"ammonium tri-chloro(dioxoethylene-O,O'-)tellurate|AS 101|AS-101"	"CCCn1c2=N/C(=c\3/cc([nH]n3C)OC(=O)CNc3ccc(c(c3)OC)OC)/N=c2c(=O)n(c1=O)CCC"	"OZNDSRMQISJHIZ-JWGURIENSA-N"	"InChI=1S/C25H31N7O6/c1-6-10-31-23-21(24(34)32(11-7-2)25(31)35)27-22(28-23)16-13-19(29-30(16)3)38-20(33)14-26-15-8-9-17(36-4)18(12-15)37-5/h8-9,12-13,26,29H,6-7,10-11,14H2,1-5H3/b22-16-"	"yes"	""	""
"14435"	"AS-1517499"	""	"Synthetic organic"	""	""	""	""	""	"10340781"	""	""	"CHEMBL228192"	""	""	""	""	"4-(benzylamino)-2-[2-(3-chloro-4-hydroxyphenyl)ethylamino]pyrimidine-5-carboxamide"	""	"AS1517499|compound 2t [PMID: 17071093]"	"O=C(C1=CN=C(NCCC2=CC=C(O)C(Cl)=C2)N=C1NCC3=CC=CC=C3)N"	"OZRMEKAUZBKTTC-UHFFFAOYSA-N"	"InChI=1S/C20H20ClN5O2/c21-16-10-13(6-7-17(16)27)8-9-23-20-25-12-15(18(22)28)19(26-20)24-11-14-4-2-1-3-5-14/h1-7,10,12,27H,8-9,11H2,(H2,22,28)(H2,23,24,25,26)"	"yes"	""	""
"10578"	"AS-252424"	""	"Synthetic organic"	""	""	""	""	"404859025"	"11630874"	""	""	"CHEMBL379156"	""	""	""	""	"(5Z)-5-[[5-(4-fluoro-2-hydroxyphenyl)furan-2-yl]methylidene]-1,3-thiazolidine-2,4-dione"	""	"AS252424|compound 26 [PMID: 16789742]"	"O=C1S/C(=C\c2ccc(o2)c2ccc(cc2O)F)/C(=O)N1"	"OYYVWNDMOQPMGE-SDQBBNPISA-N"	"InChI=1S/C14H8FNO4S/c15-7-1-3-9(10(17)5-7)11-4-2-8(20-11)6-12-13(18)16-14(19)21-12/h1-6,17H,(H,16,18,19)/b12-6-"	"yes"	""	""
"11951"	"asapiprant"	""	"Synthetic organic"	""	""	""	""	"461663506"	"59232326"	""	""	"CHEMBL3545043"	""	""	""	""	""	"asapiprant"	"BGE-175|BGE175|example II-74 [US8153793B2]|S-555739"	"CC(C)Oc1ccc(cc1)S(=O)(=O)N1CCN(CC1)c1cc(c(cc1)c1ncco1)OCC(=O)O"	"ZMZNWNTZRWXTJU-UHFFFAOYSA-N"	"InChI=1S/C24H27N3O7S/c1-17(2)34-19-4-6-20(7-5-19)35(30,31)27-12-10-26(11-13-27)18-3-8-21(24-25-9-14-32-24)22(15-18)33-16-23(28)29/h3-9,14-15,17H,10-13,16H2,1-2H3,(H,28,29)"	"yes"	""	""
"14309"	"ASF24"	""	"Synthetic organic"	""	""	""	""	"523352101"	"177924584"	""	""	""	""	""	""	""	""	""	"ASF-24"	"[O-][N+](=O)C1=CC=C(O1)C(=N)NCCC[C@H](N2C=C(N=N2)C3=CC=C(C=C3)C4=CC=CC=C4)C(=O)NCC5=CC=CC=C5"	"QMUVTATYSGAUKW-MHZLTWQESA-N"	"InChI=1S/C31H29N7O4/c32-30(28-17-18-29(42-28)38(40)41)33-19-7-12-27(31(39)34-20-22-8-3-1-4-9-22)37-21-26(35-36-37)25-15-13-24(14-16-25)23-10-5-2-6-11-23/h1-6,8-11,13-18,21,27H,7,12,19-20H2,(H2,32,33)(H,34,39)/t27-/m0/s1"	"yes"	""	""
"9279"	"asimadoline"	""	"Synthetic organic"	""	""	""	""	"318164798"	"179340"	""	""	"CHEMBL1190199"	""	""	""	""	"N-[(1S)-2-[(3S)-3-hydroxypyrrolidin-1-yl]-1-phenylethyl]-N-methyl-2,2-di(phenyl)acetamide"	"asimadoline"	"EMD 61 753|EMD 61753|EMD-61753"	"O[C@H]1CCN(C1)C[C@@H](N(C(=O)C(c1ccccc1)c1ccccc1)C)c1ccccc1"	"JHLHNYVMZCADTC-LOSJGSFVSA-N"	"InChI=1S/C27H30N2O2/c1-28(25(21-11-5-2-6-12-21)20-29-18-17-24(30)19-29)27(31)26(22-13-7-3-8-14-22)23-15-9-4-10-16-23/h2-16,24-26,30H,17-20H2,1H3/t24-,25+/m0/s1"	"yes"	""	""
"9621"	"asivatrep"	""	"Synthetic organic"	""	""	""	""	"340590251"	"56649347"	""	""	"CHEMBL3707398"	""	""	""	""	"(E)-N-[(1R)-1-[3,5-difluoro-4-(methanesulfonamido)phenyl]ethyl]-3-[2-propyl-6-(trifluoromethyl)pyridin-3-yl]prop-2-enamide"	"asivatrep"	"Example 230 [US7858621]|PAC-14028"	"CCCc1nc(ccc1/C=C/C(=O)N[C@@H](c1cc(F)c(c(c1)F)NS(=O)(=O)C)C)C(F)(F)F"	"UKGJZDSUJSPAJL-YPUOHESYSA-N"	"InChI=1S/C21H22F5N3O3S/c1-4-5-17-13(6-8-18(28-17)21(24,25)26)7-9-19(30)27-12(2)14-10-15(22)20(16(23)11-14)29-33(3,31)32/h6-12,29H,4-5H2,1-3H3,(H,27,30)/b9-7+/t12-/m1/s1"	"yes"	""	""
"9569"	"ASP4058"	""	"Synthetic organic"	""	""	""	""	"336446955"	"16755143"	""	""	""	""	""	""	""	"5-(5-(3-(Trifluoromethyl)-4-(((2S)-1,1,1-trifluoropropan-2-yl)oxy)phenyl)-1,2,4-oxadiazol-3-yl)-1H-benzimidazole"	""	"ASP-4058"	"C[C@@H](C(F)(F)F)Oc1ccc(cc1C(F)(F)F)c1onc(n1)c1ccc2c(c1)nc[nH]2"	"NJNXCJPSMWKXHO-VIFPVBQESA-N"	"InChI=1S/C19H12F6N4O2/c1-9(18(20,21)22)30-15-5-3-11(6-12(15)19(23,24)25)17-28-16(29-31-17)10-2-4-13-14(7-10)27-8-26-13/h2-9H,1H3,(H,26,27)/t9-/m0/s1"	"yes"	""	""
"4139"	"aspirin"	""	"Synthetic organic"	"yes"	""	""	""	"178100961"	"2244"	""	""	"CHEMBL25"	""	""	""	""	"2-acetyloxybenzoic acid"	""	"Acetophen&reg;|acetylsalicylic acid|Aspirin&reg;"	"CC(=O)Oc1ccccc1C(=O)O"	"BSYNRYMUTXBXSQ-UHFFFAOYSA-N"	"InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)"	"yes"	""	""
"6239"	"aspirin-triggered resolvin D1"	""	"Metabolite"	""	""	""	""	"178102860"	"16126783"	""	""	"CHEMBL519495"	""	""	""	""	"(4Z,7S,8R,9E,11E,13Z,15E,17R,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid"	""	"AT-Resolvin D1|AT-RvD1"	"CC/C=C\C[C@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CCC(=O)O)O)O)O"	"OIWTWACQMDFHJG-BJEBZIPWSA-N"	"InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21+/m1/s1"	"yes"	""	""
"9020"	"AT38"	""	"Synthetic organic"	""	""	""	""	"315661105"	"46843548"	""	""	""	""	""	""	""	"(4-carbamoyl-5-oxido-1,2,5-oxadiazol-5-ium-3-yl)methyl 2-hydroxybenzoate"	""	"[3-(aminocarbonyl)furoxan-4-yl]methyl salicylate"	"O=C(c1ccccc1O)OCc1no[n+](c1C(=O)N)[O-]"	"YWHHKFGUOITYRD-UHFFFAOYSA-N"	"InChI=1S/C11H9N3O6/c12-10(16)9-7(13-20-14(9)18)5-19-11(17)6-3-1-2-4-8(6)15/h1-4,15H,5H2,(H2,12,16)"	"yes"	""	""
"9517"	"atacicept"	""	"Peptide"	""	""	""	""	"336446904"	""	""	""	""	""	""	""	""	""	"atacicept"	"TACI-Fc|TACI-Ig"	""	""	""	"yes"	""	""
"7990"	"atezolizumab"	""	"Antibody"	"yes"	""	""	""	"249565671"	""	""	""	""	""	""	""	""	""	"atezolizumab"	"MPDL3280A|Tecentriq&reg;"	""	""	""	"yes"	""	""
"12317"	"ATI-50001"	""	"Synthetic organic"	""	""	""	""	"479821108"	"23585272"	""	""	""	""	""	""	""	"3-[[2-(3,4,5-trimethoxyanilino)-7H-purin-6-yl]amino]bicyclo[2.2.1]hept-5-ene-2-carboxamide"	""	"ATI-501|ATI50001|ATI501|example 103 [WO2007070872A1]"	"COc1cc(cc(c1OC)OC)Nc1nc2c(c(n1)NC1C3CC(C1C(=O)N)C=C3)[nH]cn2"	"NDUGGMXIZKDJRM-UHFFFAOYSA-N"	"InChI=1S/C22H25N7O4/c1-31-13-7-12(8-14(32-2)18(13)33-3)26-22-28-20-17(24-9-25-20)21(29-22)27-16-11-5-4-10(6-11)15(16)19(23)30/h4-5,7-11,15-16H,6H2,1-3H3,(H2,23,30)(H3,24,25,26,27,28,29)"	"yes"	""	""
"11326"	"atibuclimab"	""	"Antibody"	""	""	""	""	"434321761"	""	""	""	""	""	""	""	""	""	"atibuclimab"	"IC14"	""	""	""	"yes"	""	""
"9537"	"atracurium"	""	"Synthetic organic"	"yes"	""	""	""	"336446923"	"47319"	""	""	"CHEMBL1360"	""	""	""	""	"5-[3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoyloxy]pentyl 3-[1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium-2-yl]propanoate"	"atracurium besilate"	"atracurium besilate|atracurium dibesylate|BW 33A|Tracrium&reg;"	"COc1cc2c(cc1OC)CC[N+](C2Cc1ccc(c(c1)OC)OC)(C)CCC(=O)OCCCCCOC(=O)CC[N+]1(C)CCc2c(C1Cc1ccc(c(c1)OC)OC)cc(c(c2)OC)OC"	"YXSLJKQTIDHPOT-UHFFFAOYSA-N"	"InChI=1S/C53H72N2O12/c1-54(22-18-38-32-48(62-7)50(64-9)34-40(38)42(54)28-36-14-16-44(58-3)46(30-36)60-5)24-20-52(56)66-26-12-11-13-27-67-53(57)21-25-55(2)23-19-39-33-49(63-8)51(65-10)35-41(39)43(55)29-37-15-17-45(59-4)47(31-37)61-6/h14-17,30-35,42-43H,11-13,18-29H2,1-10H3/q+2"	"yes"	""	""
"6306"	"auranofin"	""	"Synthetic organic"	"yes"	""	""	""	"178102925"	"70788951"	""	""	"CHEMBL1366"	""	""	""	""	"gold(+1) cation; (2S,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxane-2-thiolate; triethylphosphane"	"auranofin"	"MMV688978|Ridaura&reg;|SK&F-39162|SK-39162"	"CC[P+]([Au-]S[C@@H]1O[C@H](COC(=O)C)[C@H]([C@@H]([C@H]1OC(=O)C)OC(=O)C)OC(=O)C)(CC)CC"	"AUJRCFUBUPVWSZ-XTZHGVARSA-M"	"InChI=1S/C14H20O9S.C6H15P.Au/c1-6(15)19-5-10-11(20-7(2)16)12(21-8(3)17)13(14(24)23-10)22-9(4)18;1-4-7(5-2)6-3;/h10-14,24H,5H2,1-4H3;4-6H2,1-3H3;/q;;+1/p-1/t10-,11-,12+,13-,14+;;/m1../s1"	"yes"	""	"yes"
"12857"	"avacincaptad pegol"	""	"Nucleic acid"	"yes"	""	""	""	"483123405"	""	""	""	"CHEMBL4297889"	""	""	""	""	""	"avacincaptad pegol"	"ARC-1905|ARC1905|Izervay&reg;|Zimura"	""	""	""	"yes"	""	""
"9450"	"avacopan"	""	"Synthetic organic"	"yes"	""	""	""	"329968390"	"49841217"	""	""	""	""	""	""	""	"(2R,3S)-2-[4-(cyclopentylamino)phenyl]-1-(2-fluoro-6-methylbenzoyl)-N-[4-methyl-3-(trifluoromethyl)phenyl]piperidine-3-carboxamide"	"avacopan"	"CCX-168|CCX168|Tavneos&reg;"	"O=C([C@H]1CCCN([C@H]1c1ccc(cc1)NC1CCCC1)C(=O)c1c(C)cccc1F)Nc1ccc(c(c1)C(F)(F)F)C"	"PUKBOVABABRILL-YZNIXAGQSA-N"	"InChI=1S/C33H35F4N3O2/c1-20-12-15-25(19-27(20)33(35,36)37)39-31(41)26-10-6-18-40(32(42)29-21(2)7-5-11-28(29)34)30(26)22-13-16-24(17-14-22)38-23-8-3-4-9-23/h5,7,11-17,19,23,26,30,38H,3-4,6,8-10,18H2,1-2H3,(H,39,41)/t26-,30-/m0/s1"	"yes"	""	""
"10522"	"avadomide"	""	"Synthetic organic"	""	""	""	""	"387065604"	"24967599"	""	""	"CHEMBL3989934"	""	""	""	""	"3-(5-amino-2-methyl-4-oxoquinazolin-3-yl)piperidine-2,6-dione"	"avadomide"	"CC-122|CC122|Compound A [WO2014039960A1]"	"O=C1CCC(C(=O)N1)n1c(C)nc2c(c1=O)c(N)ccc2"	"RSNPAKAFCAAMBH-UHFFFAOYSA-N"	"InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)"	"yes"	""	""
"10368"	"avapritinib"	""	"Synthetic organic"	"yes"	""	""	""	"384403648"	"118023034"	""	""	""	""	""	""	""	"(1S)-1-(4-fluorophenyl)-1-[2-[4-[6-(1-methylpyrazol-4-yl)pyrrolo[2,1-f][1,2,4]triazin-4-yl]piperazin-1-yl]pyrimidin-5-yl]ethanamine"	"avapritinib"	"Ayvakit&reg;|Ayvakyt&reg;|BLU-285|BLU285"	"Fc1ccc(cc1)[C@@](c1cnc(nc1)N1CCN(CC1)c1ncnn2c1cc(c2)c1cnn(c1)C)(N)C"	"DWYRIWUZIJHQKQ-SANMLTNESA-N"	"InChI=1S/C26H27FN10/c1-26(28,20-3-5-22(27)6-4-20)21-13-29-25(30-14-21)36-9-7-35(8-10-36)24-23-11-18(16-37(23)33-17-31-24)19-12-32-34(2)15-19/h3-6,11-17H,7-10,28H2,1-2H3/t26-/m0/s1"	"yes"	""	""
"11345"	"avdoralimab"	""	"Antibody"	""	""	""	""	"440816714"	""	""	""	""	""	""	""	""	""	"avdoralimab"	"anti-hC5aR-32F3A6 GL|IPH-5401|NN-8210|NNC-0215-0384"	""	""	""	"yes"	""	""
"5579"	"AVE 0991"	""	"Synthetic organic"	""	""	""	""	"178102215"	"9851724"	""	""	""	""	""	""	""	"3-ethyl-1-[3-[4-[(5-formyl-4-methoxy-2-phenylimidazol-1-yl)methyl]phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylurea"	""	"AVE-0991|AVE0991"	"CCNC(=O)NS(=O)(=O)c1sc(cc1c1ccc(cc1)Cn1c(nc(c1C=O)OC)c1ccccc1)CC(C)C"	"QTOZBSNPDCWHPV-UHFFFAOYSA-N"	"InChI=1S/C29H32N4O5S2/c1-5-30-29(35)32-40(36,37)28-24(16-23(39-28)15-19(2)3)21-13-11-20(12-14-21)17-33-25(18-34)27(38-4)31-26(33)22-9-7-6-8-10-22/h6-14,16,18-19H,5,15,17H2,1-4H3,(H2,30,32,35)"	"yes"	""	""
"8735"	"avelumab"	""	"Antibody"	"yes"	""	""	""	"252827393"	""	""	""	""	""	""	""	""	""	"avelumab"	"Bavencio&reg;|MSB-0010718C|MSB0010718C"	""	""	""	"yes"	""	""
"11253"	"AX-024"	""	"Synthetic organic"	""	""	""	""	"434122313"	"56949412"	""	""	""	""	""	""	""	""	""	"AX-24|AX024"	"COc1ccc2c(c1)C(=C(CO2)CN1CCCC1)c1ccc(cc1)F"	"VMMKGVRPILDZML-UHFFFAOYSA-N"	"InChI=1S/C21H22FNO2/c1-24-18-8-9-20-19(12-18)21(15-4-6-17(22)7-5-15)16(14-25-20)13-23-10-2-3-11-23/h4-9,12H,2-3,10-11,13-14H2,1H3"	"yes"	""	""
"7722"	"AZ11657312 (salt free)"	""	"Synthetic organic"	""	""	""	""	"223366055"	"11193842"	""	""	"CHEMBL550637"	""	""	""	""	"2-(1-adamantyl)-N-[2-methyl-5-(9-oxa-3,7-diazabicyclo[3.3.1]nonane-3-carbonyl)phenyl]acetamide"	""	""	"O=C(CC12CC3CC(C2)CC(C1)C3)Nc1cc(ccc1C)C(=O)N1CC2CNCC(C1)O2"	"XYNNEMHCLNODBL-UHFFFAOYSA-N"	"InChI=1S/C26H35N3O3/c1-16-2-3-20(25(31)29-14-21-12-27-13-22(15-29)32-21)7-23(16)28-24(30)11-26-8-17-4-18(9-26)6-19(5-17)10-26/h2-3,7,17-19,21-22,27H,4-6,8-15H2,1H3,(H,28,30)"	"yes"	""	""
"9577"	"AZ13102909"	""	"Synthetic organic"	""	""	""	""	"336446963"	"126970684"	""	""	""	""	""	""	""	"7-{2-[3-(cyclohexylformamido)propyl]hydrazin-1-yl}-2-{4'-methoxy-[1,1'-biphenyl]-4-yl}-2H,3H,3aH-imidazo[4,5-b]pyridine-6-carboxamide"	""	"AZ909"	"COc1ccc(cc1)c1ccc(cc1)C1NC2C(=N1)C(=C(C=N2)C(=O)N)NNCCCNC(=O)C1CCCCC1"	"UMLDEMVOMRDOLS-UHFFFAOYSA-N"	"InChI=1S/C30H37N7O3/c1-40-23-14-12-20(13-15-23)19-8-10-21(11-9-19)28-35-26-25(24(27(31)38)18-33-29(26)36-28)37-34-17-5-16-32-30(39)22-6-3-2-4-7-22/h8-15,18,22,28-29,34,36-37H,2-7,16-17H2,1H3,(H2,31,38)(H,32,39)"	"yes"	""	""
"10233"	"AZ2"	""	"Synthetic organic"	""	""	""	""	"381744915"	"134163708"	""	""	""	""	""	""	""	"N-(5-{2-[(1S)-1-cyclopropylethyl]-7-methyl-1-oxo-2,3-dihydro-1H-isoindol-5-yl}-4-methyl-1,3-thiazol-2-yl)acetamide"	""	""	"CC(=O)Nc1sc(c(n1)C)c1cc(C)c2c(c1)CN(C2=O)[C@H](C1CC1)C"	"CNCRCDLWUGCPSJ-LBPRGKRZSA-N"	"InChI=1S/C20H23N3O2S/c1-10-7-15(18-11(2)21-20(26-18)22-13(4)24)8-16-9-23(19(25)17(10)16)12(3)14-5-6-14/h7-8,12,14H,5-6,9H2,1-4H3,(H,21,22,24)/t12-/m0/s1"	"yes"	""	""
"13722"	"AZ3246"	""	"Synthetic organic"	""	""	""	""	"507750356"	"166485054"	""	""	""	""	""	""	""	"5-cyclopropyl-6-(3-methylimidazo[4,5-c]pyridin-7-yl)-3-[[3-methyl-1-(2,2,2-trifluoroethyl)pyrazol-4-yl]amino]pyrazine-2-carboxamide"	""	"AZ-3246|compound 24 [PMID: 39928839]"	"FC(F)(F)CN1N=C(C(=C1)NC2=NC(=C(N=C2C(=O)N)C3=C4N=CN(C4=CN=C3)C)C5CC5)C"	"YLGMPWWMPCGYBF-UHFFFAOYSA-N"	"InChI=1S/C21H20F3N9O/c1-10-13(7-33(31-10)8-21(22,23)24)28-20-18(19(25)34)29-17(15(30-20)11-3-4-11)12-5-26-6-14-16(12)27-9-32(14)2/h5-7,9,11H,3-4,8H2,1-2H3,(H2,25,34)(H,28,30)"	"yes"	""	""
"9560"	"AZ3451"	""	"Synthetic organic"	""	""	""	""	"336446946"	"126961335"	""	""	""	""	""	""	""	"2-(6-bromanyl-1,3-benzodioxol-5-yl)-~{N}-(4-cyanophenyl)-1-[(1~{S})-1-cyclohexylethyl]benzimidazole-5-carboxamide"	""	""	"N#Cc1ccc(cc1)NC(=O)c1ccc2c(c1)nc(n2[C@H](C1CCCCC1)C)c1cc2OCOc2cc1Br"	"FJAOGFGHTPYADT-SFHVURJKSA-N"	"InChI=1S/C30H27BrN4O3/c1-18(20-5-3-2-4-6-20)35-26-12-9-21(30(36)33-22-10-7-19(16-32)8-11-22)13-25(26)34-29(35)23-14-27-28(15-24(23)31)38-17-37-27/h7-15,18,20H,2-6,17H2,1H3,(H,33,36)/t18-/m0/s1"	"yes"	""	""
"9586"	"AZ7188"	""	"Synthetic organic"	""	""	""	""	"340590217"	"129320516"	""	""	""	""	""	""	""	"2,3-dihydro-1'H-[2,3'-biindole]-1-carbaldehyde"	""	""	"O=CN1c2ccccc2CC1c1c[nH]c2c1cccc2"	"GFACBUCIUAKRSV-UHFFFAOYSA-N"	"InChI=1S/C17H14N2O/c20-11-19-16-8-4-1-5-12(16)9-17(19)14-10-18-15-7-3-2-6-13(14)15/h1-8,10-11,17-18H,9H2"	"yes"	""	""
"9585"	"AZ8838"	""	"Synthetic organic"	""	""	""	""	"340590216"	"126961334"	""	""	""	""	""	""	""	"(S)-(4-fluoro-2-propylphenyl)(1H-imidazol-2-yl)methanol"	""	""	"CCCc1cc(F)ccc1[C@@H](c1ncc[nH]1)O"	"IDFPQEHZYBXIFO-LBPRGKRZSA-N"	"InChI=1S/C13H15FN2O/c1-2-3-9-8-10(14)4-5-11(9)12(17)13-15-6-7-16-13/h4-8,12,17H,2-3H2,1H3,(H,15,16)/t12-/m0/s1"	"yes"	""	""
"6796"	"azacitidine"	""	"Synthetic organic"	"yes"	""	""	""	"178103402"	"9444"	""	""	"CHEMBL1489"	""	""	""	""	"4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one"	"azacitidine"	"5-AZAC|5-azacytidine|ladakamycin|Onureg&reg;|Onureg&reg; (CC-486; oral azacitidine)|U-18496|Vidaza&reg;"	"OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc(nc1=O)N"	"NMUSYJAQQFHJEW-KVTDHHQDSA-N"	"InChI=1S/C8H12N4O5/c9-7-10-2-12(8(16)11-7)6-5(15)4(14)3(1-13)17-6/h2-6,13-15H,1H2,(H2,9,11,16)/t3-,4-,5-,6-/m1/s1"	"yes"	""	""
"9221"	"azapro-3"	""	"Peptide"	""	""	""	""	"315661297"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"7119"	"azatadine"	""	"Synthetic organic"	"yes"	""	""	""	"178103696"	"19861"	""	""	"CHEMBL946"	""	""	""	""	"11-(1-methylpiperidin-4-ylidene)-5,6-dihydrobenzo[1,2]cyclohepta[3,4-b]pyridine"	"azatadine"	"Optimine&reg;|SCH-10649"	"CN1CCC(=C2c3ccccc3CCc3c2nccc3)CC1"	"SEBMTIQKRHYNIT-UHFFFAOYSA-N"	"InChI=1S/C20H22N2/c1-22-13-10-16(11-14-22)19-18-7-3-2-5-15(18)8-9-17-6-4-12-21-20(17)19/h2-7,12H,8-11,13-14H2,1H3"	"yes"	""	""
"7120"	"azathioprine"	""	"Synthetic organic"	"yes"	""	""	""	"178103697"	"2265"	""	""	"CHEMBL1542"	""	""	""	""	"6-[(1-methyl-4-nitro-1H-imidazol-5-yl)sulfanyl]-9H-purine"	"azathioprine"	"Azasan&reg;|BW-57-322|Imuran&reg;|Jayempi&reg;"	"Cn1cnc(c1Sc1ncnc2c1nc[nH]2)N(=O)=O"	"LMEKQMALGUDUQG-UHFFFAOYSA-N"	"InChI=1S/C9H7N7O2S/c1-15-4-14-7(16(17)18)9(15)19-8-5-6(11-2-10-5)12-3-13-8/h2-4H,1H3,(H,10,11,12,13)"	"yes"	""	""
"11711"	"AZD0284"	""	"Synthetic organic"	""	""	""	""	"442878737"	"129205086"	""	""	""	""	""	""	""	""	""	"AZD-0284|compound 20 [PMID: 34464130]"	"FC(F)(F)C(O)(C(F)(F)F)c1ccc(cc1)NC(=O)[C@@H]1N(Cc2c1ccc(c2)S(=O)(=O)C)C(=O)C"	"QYYZXEPEVBXNNA-QGZVFWFLSA-N"	"InChI=1S/C21H18F6N2O5S/c1-11(30)29-10-12-9-15(35(2,33)34)7-8-16(12)17(29)18(31)28-14-5-3-13(4-6-14)19(32,20(22,23)24)21(25,26)27/h3-9,17,32H,10H2,1-2H3,(H,28,31)/t17-/m1/s1"	"yes"	""	""
"7844"	"AZD1236"	""	"Synthetic organic"	""	""	""	""	"223366174"	"24751752"	""	""	""	""	""	""	""	"(5S)-5-[[4-(5-chloropyridin-2-yl)oxypiperidin-1-yl]sulfonylmethyl]-5-methylimidazolidine-2,4-dione"	""	"AZD 1236|AZD-1236"	"O=C1NC(=O)[C@@](N1)(C)CS(=O)(=O)N1CCC(CC1)Oc1ccc(cn1)Cl"	"SFJFBTPHDHUUPU-OAHLLOKOSA-N"	"InChI=1S/C15H19ClN4O5S/c1-15(13(21)18-14(22)19-15)9-26(23,24)20-6-4-11(5-7-20)25-12-3-2-10(16)8-17-12/h2-3,8,11H,4-7,9H2,1H3,(H2,18,19,21,22)/t15-/m1/s1"	"yes"	""	""
"9679"	"AZD1678"	""	"Synthetic organic"	""	""	""	""	"348353638"	"23585443"	""	""	""	""	""	""	""	"2,3-dichloro-N-(5-fluoro-3-methoxypyrazin-2-yl)benzenesulfonamide"	""	"AZD-1678|compound 49 [PMID: 28947948]"	"COc1nc(F)cnc1NS(=O)(=O)c1cccc(c1Cl)Cl"	"NWSUDJQTTGDPIR-UHFFFAOYSA-N"	"InChI=1S/C11H8Cl2FN3O3S/c1-20-11-10(15-5-8(14)16-11)17-21(18,19)7-4-2-3-6(12)9(7)13/h2-5H,1H3,(H,15,17)"	"yes"	""	""
"7680"	"AZD1981"	""	"Synthetic organic"	""	""	""	""	"223366015"	"11292191"	""	""	"CHEMBL1914489"	""	""	""	""	"2-[4-acetamido-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid"	""	"AZD 1981|AZD-1981"	"CC(=O)Nc1cccc2c1c(Sc1ccc(cc1)Cl)c(n2CC(=O)O)C"	"JWYIGNODXSRKGP-UHFFFAOYSA-N"	"InChI=1S/C19H17ClN2O3S/c1-11-19(26-14-8-6-13(20)7-9-14)18-15(21-12(2)23)4-3-5-16(18)22(11)10-17(24)25/h3-9H,10H2,1-2H3,(H,21,23)(H,24,25)"	"yes"	""	""
"9678"	"AZD2098"	""	"Synthetic organic"	""	""	""	""	"348353637"	"10308720"	""	""	""	""	""	""	""	"2,3-dichloro-N-(3-methoxypyrazin-2-yl)benzenesulfonamide"	""	"AZD-2098|compound 47 [PMID: 28947948]"	"COc1nccnc1NS(=O)(=O)c1cccc(c1Cl)Cl"	"FLSMVCMSUNISFK-UHFFFAOYSA-N"	"InChI=1S/C11H9Cl2N3O3S/c1-19-11-10(14-5-6-15-11)16-20(17,18)8-4-2-3-7(12)9(8)13/h2-6H,1H3,(H,14,16)"	"yes"	""	""
"7825"	"AZD2423"	""	"Synthetic organic"	""	""	""	""	"223366156"	"46213922"	""	""	""	""	""	""	""	"4-[(2R)-4-tert-butylpiperazine-2-carbonyl]-N-(4-chloro-3-fluorophenyl)piperazine-1-carboxamide"	""	"AZD 2423|AZD-2423"	"O=C(N1CCN(CC1)C(=O)[C@@H]1NCCN(C1)C(C)C)Nc1ccc(c(c1)F)Cl"	"WERHXSXPOAOBJV-QGZVFWFLSA-N"	"InChI=1S/C19H27ClFN5O2/c1-13(2)26-6-5-22-17(12-26)18(27)24-7-9-25(10-8-24)19(28)23-14-3-4-15(20)16(21)11-14/h3-4,11,13,17,22H,5-10,12H2,1-2H3,(H,23,28)/t17-/m1/s1"	"yes"	""	""
"9997"	"AZD3458"	""	"Synthetic organic"	""	""	""	""	"374883884"	"134611894"	""	""	"CHEMBL4126156"	""	""	""	""	""	""	"AZD-3458|compound 15 [PMID: 29852070]"	"CC(=O)Nc1sc(c(n1)C)c1cc2CN(C(=O)c2c(c1)S(=O)(=O)C)[C@H](C1CC1)C"	"PAQUFWFUOVDUIO-NSHDSACASA-N"	"InChI=1S/C20H23N3O4S2/c1-10-18(28-20(21-10)22-12(3)24)14-7-15-9-23(11(2)13-5-6-13)19(25)17(15)16(8-14)29(4,26)27/h7-8,11,13H,5-6,9H2,1-4H3,(H,21,22,24)/t11-/m0/s1"	"yes"	""	""
"10605"	"AZD3965"	""	"Synthetic organic"	""	""	""	""	"404859052"	"10369242"	""	""	""	""	""	""	""	"5-[(4S)-4-hydroxy-4-methyl-1,2-oxazolidine-2-carbonyl]-3-methyl-6-[[5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]methyl]-1-propan-2-ylthieno[2,3-d]pyrimidine-2,4-dione"	""	"AZD-3965"	"O=C(c1c(Cc2c(C)[nH]nc2C(F)(F)F)sc2c1c(=O)n(c(=O)n2C(C)C)C)N1OC[C@@](C1)(C)O"	"PRNXOFBDXNTIFG-FQEVSTJZSA-N"	"InChI=1S/C21H24F3N5O5S/c1-9(2)29-18-14(16(30)27(5)19(29)32)13(17(31)28-7-20(4,33)8-34-28)12(35-18)6-11-10(3)25-26-15(11)21(22,23)24/h9,33H,6-8H2,1-5H3,(H,25,26)/t20-/m0/s1"	"yes"	""	""
"8948"	"AZD5069"	""	"Synthetic organic"	""	""	""	""	"310264729"	"56645576"	""	""	""	""	""	""	""	"N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[(2R,3S)-3,4-dihydroxybutan-2-yl]oxypyrimidin-4-yl]azetidine-1-sulfonamide"	""	"AZD-5069"	"OC[C@@H]([C@H](Oc1nc(SCc2cccc(c2F)F)nc(c1)NS(=O)(=O)N1CCC1)C)O"	"QZECRCLSIGFCIO-RISCZKNCSA-N"	"InChI=1S/C18H22F2N4O5S2/c1-11(14(26)9-25)29-16-8-15(23-31(27,28)24-6-3-7-24)21-18(22-16)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,25-26H,3,6-7,9-10H2,1H3,(H,21,22,23)/t11-,14+/m1/s1"	"yes"	""	""
"13017"	"AZD5423"	""	"Synthetic organic"	""	""	""	""	"485206138"	"24825740"	""	""	"CHEMBL4072756"	""	""	""	""	"2,2,2-trifluoro-N-[(1R,2S)-1-[1-(4-fluorophenyl)indazol-5-yl]oxy-1-(3-methoxyphenyl)propan-2-yl]acetamide"	""	"AZD-5423|compound 1b [PMID: 28937774]"	"C[C@@H]([C@@H](C1=CC(=CC=C1)OC)OC2=CC3=C(C=C2)N(N=C3)C4=CC=C(C=C4)F)NC(=O)C(F)(F)F"	"FCNQMDSJHADDFT-WNSKOXEYSA-N"	"InChI=1S/C25H21F4N3O3/c1-15(31-24(33)25(27,28)29)23(16-4-3-5-20(12-16)34-2)35-21-10-11-22-17(13-21)14-30-32(22)19-8-6-18(26)7-9-19/h3-15,23H,1-2H3,(H,31,33)/t15-,23-/m0/s1"	"yes"	""	""
"7686"	"AZD5672"	""	"Synthetic organic"	""	""	""	""	"223366021"	"11614352"	""	""	"CHEMBL1951914"	""	""	""	""	"N-[1-[(3R)-3-(3,5-difluorophenyl)-3-(1-methylsulfonylpiperidin-4-yl)propyl]piperidin-4-yl]-N-ethyl-2-(4-methylsulfonylphenyl)acetamide"	""	"AZD 5672|AZD-5672"	"CCN(C(=O)Cc1ccc(cc1)S(=O)(=O)C)C1CCN(CC1)CC[C@@H](c1cc(F)cc(c1)F)C1CCN(CC1)S(=O)(=O)C"	"QOSMEMHKXNNIGG-SSEXGKCCSA-N"	"InChI=1S/C31H43F2N3O5S2/c1-4-36(31(37)19-23-5-7-29(8-6-23)42(2,38)39)28-11-14-34(15-12-28)16-13-30(25-20-26(32)22-27(33)21-25)24-9-17-35(18-10-24)43(3,40)41/h5-8,20-22,24,28,30H,4,9-19H2,1-3H3/t30-/m1/s1"	"yes"	""	""
"10352"	"AZD5718"	""	"Synthetic organic"	""	""	""	""	"384403633"	"122678117"	""	""	""	""	""	""	""	"(1R,2R)-2-[4-(5-methyl-1H-pyrazol-3-yl)benzoyl]-N-(4-oxo-6,7-dihydro-5H-pyrazolo[1,5-a]pyrazin-3-yl)cyclohexane-1-carboxamide"	""	"compound 12 [PMID: 30869888]"	"O=C([C@@H]1CCCC[C@H]1C(=O)c1ccc(cc1)c1n[nH]c(c1)C)Nc1cnn2c1C(=O)NCC2"	"ROTWSDMXHVGAHZ-QZTJIDSGSA-N"	"InChI=1S/C24H26N6O3/c1-14-12-19(29-28-14)15-6-8-16(9-7-15)22(31)17-4-2-3-5-18(17)23(32)27-20-13-26-30-11-10-25-24(33)21(20)30/h6-9,12-13,17-18H,2-5,10-11H2,1H3,(H,25,33)(H,27,32)(H,28,29)/t17-,18-/m1/s1"	"yes"	""	""
"7823"	"AZD6605"	""	"Synthetic organic"	""	""	""	""	"223366154"	"11641563"	""	""	"CHEMBL2409707"	""	""	""	""	"(5S)-5-methyl-5-[[4-[4-(1,1,2,2-tetrafluoroethoxy)phenoxy]piperidin-1-yl]sulfonylmethyl]imidazolidine-2,4-dione"	""	"AZ 11920155|AZ-11920155|AZ11920155|AZD 6605|AZD-6605"	"FC(C(Oc1ccc(cc1)OC1CCN(CC1)S(=O)(=O)C[C@@]1(C)NC(=O)NC1=O)(F)F)F"	"SBVAXUGOISPYPX-QGZVFWFLSA-N"	"InChI=1S/C18H21F4N3O6S/c1-17(15(26)23-16(27)24-17)10-32(28,29)25-8-6-12(7-9-25)30-11-2-4-13(5-3-11)31-18(21,22)14(19)20/h2-5,12,14H,6-10H2,1H3,(H2,23,24,26,27)/t17-/m1/s1"	"yes"	""	""
"7687"	"AZD6703"	""	"Synthetic organic"	""	""	""	""	"223366022"	"11373432"	""	""	"CHEMBL2031465"	""	""	""	""	"N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3-yl]benzamide"	""	"AZ 12012199|AZ-12012199|AZ12012199|AZD 6703|AZD-6703"	"CN1CCN(CC1)c1ccc2c(c1)c(=O)n(cn2)c1cc(ccc1C)C(=O)NC1CC1"	"ZMAZXHICVRYLQN-UHFFFAOYSA-N"	"InChI=1S/C24H27N5O2/c1-16-3-4-17(23(30)26-18-5-6-18)13-22(16)29-15-25-21-8-7-19(14-20(21)24(29)31)28-11-9-27(2)10-12-28/h3-4,7-8,13-15,18H,5-6,9-12H2,1-2H3,(H,26,30)"	"yes"	""	""
"11714"	"AZD7624"	""	"Synthetic organic"	""	""	""	""	"458923749"	"25143624"	""	""	""	""	""	""	""	"N-cyclopropyl-3-fluoro-4-methyl-5-[3-[[1-[2-[2-(methylamino)ethoxy]phenyl]cyclopropyl]amino]-2-oxopyrazin-1-yl]benzamide"	""	"AZD-7624|Example 259 [WO2009001132]"	"Cc1c(cc(cc1F)C(=O)NC1CC1)n1ccnc(c1=O)NC1(CC1)c1ccccc1OCCNC"	"NNKPHNTWNILINE-UHFFFAOYSA-N"	"InChI=1S/C27H30FN5O3/c1-17-21(28)15-18(25(34)31-19-7-8-19)16-22(17)33-13-11-30-24(26(33)35)32-27(9-10-27)20-5-3-4-6-23(20)36-14-12-29-2/h3-6,11,13,15-16,19,29H,7-10,12,14H2,1-2H3,(H,30,32)(H,31,34)"	"yes"	""	""
"11204"	"AZD8154"	""	"Synthetic organic"	""	""	""	""	"434122264"	"141754136"	""	""	""	""	""	""	""	"2-[(1S)-1-cyclopropylethyl]-5-[4-methyl-2-[[6-(2-oxopyrrolidin-1-yl)pyridin-2-yl]amino]-1,3-thiazol-5-yl]-7-methylsulfonyl-3H-isoindol-1-one"	""	"AZD-8154|Example 1 [WO2018055040A1]"	"C[C@H](N1Cc2c(C1=O)c(cc(c2)c1sc(nc1C)Nc1cccc(n1)N1CCCC1=O)S(=O)(=O)C)C1CC1"	"XOMFDZJQLSPGGV-INIZCTEOSA-N"	"InChI=1S/C27H29N5O4S2/c1-15-25(37-27(28-15)30-21-6-4-7-22(29-21)31-11-5-8-23(31)33)18-12-19-14-32(16(2)17-9-10-17)26(34)24(19)20(13-18)38(3,35)36/h4,6-7,12-13,16-17H,5,8-11,14H2,1-3H3,(H,28,29,30)/t16-/m0/s1"	"yes"	""	""
"9256"	"AZD8848"	""	"Synthetic organic"	""	""	""	""	"315661331"	"11592228"	""	""	""	""	""	""	""	"methyl 2-(3-(((3-(6-amino-2-butoxy-8-oxo-7,8-dihydro-9H-purin-9-yl)propyl)(3-morpholinopropyl)amino)methyl)phenyl)acetate"	""	"DSP-3025"	"CCCCOc1nc(N)c2c(n1)n(CCCN(Cc1cccc(c1)CC(=O)OC)CCCN1CCOCC1)c(=O)[nH]2"	"FEFIBEHSXLKJGI-UHFFFAOYSA-N"	"InChI=1S/C29H43N7O5/c1-3-4-16-41-28-32-26(30)25-27(33-28)36(29(38)31-25)13-7-12-35(11-6-10-34-14-17-40-18-15-34)21-23-9-5-8-22(19-23)20-24(37)39-2/h5,8-9,19H,3-4,6-7,10-18,20-21H2,1-2H3,(H,31,38)(H2,30,32,33)"	"yes"	""	""
"7826"	"AZD9056"	""	"Synthetic organic"	""	""	""	""	"223366157"	"10161381"	""	""	""	""	""	""	""	"N-(1-adamantylmethyl)-2-chloro-5-[3-(3-hydroxypropylamino)propyl]benzamide"	""	"AZD 9056|AZD-9056"	"OCCCNCCCc1ccc(c(c1)C(=O)NCC12CC3CC(C2)CC(C1)C3)Cl"	"HSQAARMBHJCUOK-UHFFFAOYSA-N"	"InChI=1S/C24H35ClN2O2/c25-22-5-4-17(3-1-6-26-7-2-8-28)12-21(22)23(29)27-16-24-13-18-9-19(14-24)11-20(10-18)15-24/h4-5,12,18-20,26,28H,1-3,6-11,13-16H2,(H,27,29)"	"yes"	""	""
"9812"	"AZD9567"	""	"Synthetic organic"	""	""	""	""	"354702284"	"121248172"	""	""	""	""	""	""	""	"2,2-difluoro-N-[(1R,2S)-3-methyl-1-[1-(1-methyl-6-oxopyridin-3-yl)indazol-5-yl]oxy-1-phenylbutan-2-yl]propanamide"	""	"AZD 9567|AZD-9567|compound 15 [PMID: 29424542]|example 1 [WO2016046260A1]"	"CC([C@@H]([C@@H](c1ccccc1)Oc1ccc2c(c1)cnn2c1ccc(=O)n(c1)C)NC(=O)C(F)(F)C)C"	"ZQFNDBISEYQVRR-LOSJGSFVSA-N"	"InChI=1S/C27H28F2N4O3/c1-17(2)24(31-26(35)27(3,28)29)25(18-8-6-5-7-9-18)36-21-11-12-22-19(14-21)15-30-33(22)20-10-13-23(34)32(4)16-20/h5-17,24-25H,1-4H3,(H,31,35)/t24-,25+/m0/s1"	"yes"	""	""
"10479"	"AZD9898"	""	"Synthetic organic"	""	""	""	""	"385612238"	"122670110"	""	""	"CHEMBL3961833"	""	""	""	""	"(1S,2S)-2-[5-(5-chloro-2,4-difluoro-N-(2-fluoro-2-methylpropyl)anilino)-3-methoxypyrazine-2-carbonyl]cyclopropane-1-carboxylic acid"	""	"AZD-9898|example 62 [WO2016177845A1]"	"COc1nc(cnc1C(=O)[C@H]1C[C@@H]1C(=O)O)N(c1cc(Cl)c(cc1F)F)CC(F)(C)C"	"RVMWIVNHZMXEHS-UWVGGRQHSA-N"	"InChI=1S/C20H19ClF3N3O4/c1-20(2,24)8-27(14-5-11(21)12(22)6-13(14)23)15-7-25-16(18(26-15)31-3)17(28)9-4-10(9)19(29)30/h5-7,9-10H,4,8H2,1-3H3,(H,29,30)/t9-,10-/m0/s1"	"yes"	""	""
"7484"	"azelaic acid"	""	"Synthetic organic"	"yes"	""	""	""	"187051787"	"2266"	""	""	"CHEMBL1238"	""	""	""	""	"Nonanedioic acid"	"azelaic acid"	"Azelex&reg;|Finacea&reg;|ZK-62498"	"OC(=O)CCCCCCCC(=O)O"	"BDJRBEYXGGNYIS-UHFFFAOYSA-N"	"InChI=1S/C9H16O4/c10-8(11)6-4-2-1-3-5-7-9(12)13/h1-7H2,(H,10,11)(H,12,13)"	"yes"	""	""
"6510"	"azithromycin"	""	"Synthetic organic"	"yes"	""	""	""	"178103124"	"447043"	""	""	"CHEMBL529"	""	""	""	""	"(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-dimethylamino-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one"	"azithromycin"	""	"CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@@H]2O[C@@H](C)[C@@H]([C@](C2)(C)OC)O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C[C@H](CN([C@@H]([C@H]([C@]1(C)O)O)C)C)C)(C)O"	"MQTOSJVFKKJCRP-BICOPXKESA-N"	"InChI=1S/C38H72N2O12/c1-15-27-38(10,46)31(42)24(6)40(13)19-20(2)17-36(8,45)33(52-35-29(41)26(39(11)12)16-21(3)48-35)22(4)30(23(5)34(44)50-27)51-28-18-37(9,47-14)32(43)25(7)49-28/h20-33,35,41-43,45-46H,15-19H2,1-14H3/t20-,21-,22+,23-,24-,25+,26+,27-,28+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1"	"yes"	"yes"	"yes"
"7906"	"bafetinib"	""	"Synthetic organic"	""	""	""	""	"249565589"	"11387605"	""	""	"CHEMBL206834"	""	""	""	""	"4-[[(3S)-3-dimethylaminopyrrolidin-1-yl]methyl]-N-[4-methyl-3-[(4-pyrimidin-5-ylpyrimidin-2-yl)amino]phenyl]-3-(trifluoromethyl)benzamide"	"bafetinib"	"INNO-406|Lyn-IN-1|NS-187"	"CN([C@H]1CCN(C1)Cc1ccc(cc1C(F)(F)F)C(=O)Nc1ccc(c(c1)Nc1nccc(n1)c1cncnc1)C)C"	"ZGBAJMQHJDFTQJ-DEOSSOPVSA-N"	"InChI=1S/C30H31F3N8O/c1-19-4-7-23(13-27(19)39-29-36-10-8-26(38-29)22-14-34-18-35-15-22)37-28(42)20-5-6-21(25(12-20)30(31,32)33)16-41-11-9-24(17-41)40(2)3/h4-8,10,12-15,18,24H,9,11,16-17H2,1-3H3,(H,37,42)(H,36,38,39)/t24-/m0/s1"	"yes"	""	""
"5069"	"BAFF"	"Human"	"Peptide"	""	""	""	""	"178101762"	""	"Q9Y275"	"ENSG00000102524"	""	""	""	""	""	""	""	"B cell-activating factor|CD257 antigen|dendritic cell-derived TNF-like molecule"	""	""	""	"yes"	""	""
"13076"	"baicalin"	""	"Natural product"	""	""	""	""	"491299858"	"64982"	""	""	"CHEMBL485818"	""	""	""	""	"(2S,3S,4S,5R,6S)-6-(5,6-dihydroxy-4-oxo-2-phenylchromen-7-yl)oxy-3,4,5-trihydroxyoxane-2-carboxylic acid"	""	"7-D-glucuronic acid-5,6-dihydroxy-flavone|Baicalein 7-glucuronide|compound 15 [PMID: 37666112]"	"C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O[C@H]4[C@@H]([C@H]([C@@H]([C@H](O4)C(=O)O)O)O)O)O)O"	"IKIIZLYTISPENI-ZFORQUDYSA-N"	"InChI=1S/C21H18O11/c22-9-6-10(8-4-2-1-3-5-8)30-11-7-12(14(23)15(24)13(9)11)31-21-18(27)16(25)17(26)19(32-21)20(28)29/h1-7,16-19,21,23-27H,(H,28,29)/t16-,17-,18+,19-,21+/m0/s1"	"yes"	""	""
"14533"	"BAL-0028"	""	"Synthetic organic"	""	""	""	""	""	"165385399"	""	""	"CHEMBL5594893"	""	""	""	""	"3-ethoxy-4-(3-fluorophenyl)-N-(1H-indazol-7-ylmethyl)-N-methylbenzamide"	""	"BAL0028|structure No. 004 [US20230365507]"	"CCOC1=C(C=CC(=C1)C(=O)N(C)CC2=CC=CC3=C2NN=C3)C4=CC(=CC=C4)F"	"VTZLXMQBXAOBJF-UHFFFAOYSA-N"	"InChI=1S/C24H22FN3O2/c1-3-30-22-13-17(10-11-21(22)16-6-5-9-20(25)12-16)24(29)28(2)15-19-8-4-7-18-14-26-27-23(18)19/h4-14H,3,15H2,1-2H3,(H,26,27)"	"yes"	""	""
"14534"	"BAL-0598"	""	"Synthetic organic"	""	""	""	""	""	"165385363"	""	""	""	""	""	""	""	"3-ethoxy-4-(3-fluorophenyl)-N-[[4-(hydroxymethyl)-1H-pyrazolo[4,5-c]pyridin-7-yl]methyl]-N-methylbenzamide"	""	"BAL0598|structure No. 054 [US2024067648]"	"C=1C=C(C=2C(OCC)=CC(C(N(C)CC3=CN=C(CO)C=4C=NNC34)=O)=CC2)C=C(F)C1"	"QLADPOCALVNSPU-UHFFFAOYSA-N"	"InChI=1S/C24H23FN4O3/c1-3-32-22-10-16(7-8-19(22)15-5-4-6-18(25)9-15)24(31)29(2)13-17-11-26-21(14-30)20-12-27-28-23(17)20/h4-12,30H,3,13-14H2,1-2H3,(H,27,28)"	"yes"	""	""
"14535"	"BAL-1516"	""	"Synthetic organic"	""	""	""	""	""	""	""	""	""	""	""	""	""	"3-ethoxy-N-methyl-N-[(1R)-1-(4-methyl-1H-pyrazolo[4,3-c]pyridin-7-yl)ethyl]-4-(4-methyl-1,3-thiazol-2-yl)benzamide"	""	""	"C=12C(C)=NC=C([C@@H](C)N(C(=O)C=3C=C(OCC)C(C4=NC(C)=CS4)=CC3)C)C1NN=C2"	"MFSJYCVXQNOKQW-OAHLLOKOSA-N"	"InChI=1S/C23H25N5O2S/c1-6-30-20-9-16(7-8-17(20)22-26-13(2)12-31-22)23(29)28(5)15(4)19-10-24-14(3)18-11-25-27-21(18)19/h7-12,15H,6H2,1-5H3,(H,25,27)/t15-/m1/s1"	"yes"	""	""
"9925"	"balamapimod"	""	"Synthetic organic"	""	""	""	""	"363894219"	"11478684"	""	""	"CHEMBL2104954"	""	""	""	""	"4-[3-chloro-4-(1-methylimidazol-2-yl)sulfanylanilino]-6-methoxy-7-(4-pyrrolidin-1-ylpiperidin-1-yl)quinoline-3-carbonitrile"	"balamapimod"	"MKI-833|MKI833"	"COc1cc2c(cc1N1CCC(CC1)N1CCCC1)ncc(c2Nc1ccc(c(c1)Cl)Sc1nccn1C)C#N"	"CVAKNHIXTWLGJO-UHFFFAOYSA-N"	"InChI=1S/C30H32ClN7OS/c1-36-14-9-33-30(36)40-28-6-5-21(15-24(28)31)35-29-20(18-32)19-34-25-17-26(27(39-2)16-23(25)29)38-12-7-22(8-13-38)37-10-3-4-11-37/h5-6,9,14-17,19,22H,3-4,7-8,10-13H2,1-2H3,(H,34,35)"	"yes"	""	""
"13800"	"balertatug"	""	"Antibody"	""	""	""	""	"507750433"	""	""	""	""	""	""	""	""	""	"balertatug"	""	""	""	""	"yes"	""	""
"13583"	"balinatunfib"	""	"Synthetic organic"	""	""	""	""	"504705402"	"132042903"	""	""	""	""	""	""	""	""	"balinatunfib"	"SAR-441566|SAR441566"	"CN1[C@@H]2C[C@H](C3=C(C1=O)C=CC=C3OC(F)F)N4C2=NC5=C4C=C(C=C5)C6=CN=C(N=C6)C7(CCC7)N"	"UROFXMLQPAUCGV-WOJBJXKFSA-N"	"InChI=1S/C27H24F2N6O2/c1-34-20-11-19(22-16(24(34)36)4-2-5-21(22)37-26(28)29)35-18-10-14(6-7-17(18)33-23(20)35)15-12-31-25(32-13-15)27(30)8-3-9-27/h2,4-7,10,12-13,19-20,26H,3,8-9,11,30H2,1H3/t19-,20-/m1/s1"	"yes"	""	""
"4891"	"B and T lymphocyte attenuator"	"Human"	"Peptide"	""	""	""	""	"178101591"	""	"Q7Z6A9"	"ENSG00000186265"	""	""	""	""	""	""	""	"B- and T-lymphocyte attenuator|B- and T-lymphocyte-associated protein|BTLA|CD272"	""	""	""	"yes"	""	""
"2717"	"bardoxolone"	""	"Synthetic organic"	""	""	""	""	"135650061"	"400010"	""	""	"CHEMBL1093059"	""	""	""	""	"(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicene-4a-carboxylic acid"	"bardoxolone"	"CDDO|RTA-401"	"N#CC1=C[C@@]2(C)[C@H](C(C1=O)(C)C)CC[C@@]1(C2=CC(=O)[C@H]2[C@@]1(C)CC[C@@]1([C@H]2CC(C)(C)CC1)C(=O)O)C"	"TXGZJQLMVSIZEI-UQMAOPSPSA-N"	"InChI=1S/C31H41NO4/c1-26(2)10-12-31(25(35)36)13-11-30(7)23(19(31)16-26)20(33)14-22-28(5)15-18(17-32)24(34)27(3,4)21(28)8-9-29(22,30)6/h14-15,19,21,23H,8-13,16H2,1-7H3,(H,35,36)/t19-,21-,23-,28-,29+,30+,31-/m0/s1"	"yes"	""	""
"7792"	"baricitinib"	""	"Synthetic organic"	"yes"	""	""	""	"223366123"	"44205240"	""	""	"CHEMBL2105759"	""	""	""	""	"2-(3-(4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-1-(ethylsulfonyl)azetidin-3-yl)acetonitrile"	"baricitinib"	"INCB-028050|INCB028050|LY-3009104|LY3009104|Olumiant&reg;"	"N#CCC1(CN(C1)S(=O)(=O)CC)n1ncc(c1)c1ncnc2c1cc[nH]2"	"XUZMWHLSFXCVMG-UHFFFAOYSA-N"	"InChI=1S/C16H17N7O2S/c1-2-26(24,25)22-9-16(10-22,4-5-17)23-8-12(7-21-23)14-13-3-6-18-15(13)20-11-19-14/h3,6-8,11H,2,4,9-10H2,1H3,(H,18,19,20)"	"yes"	""	""
"6879"	"basiliximab"	""	"Antibody"	"yes"	""	""	""	"178103461"	""	""	""	""	""	""	""	""	""	"basiliximab"	"CHI-621|L04AC02|SDZ-CHI-621|Simulect&reg;"	""	""	""	"yes"	""	""
"13805"	"batoclimab"	""	"Antibody"	""	""	""	""	"507750438"	""	""	""	""	""	""	""	""	""	"batoclimab"	"HBM9161|HL161|HL161ANS|IMVT-1401|RVT-1401"	""	""	""	"yes"	""	""
"5934"	"BAY 11-7082"	""	"Synthetic organic"	""	""	""	""	"178102557"	"5353431"	""	""	"CHEMBL403183"	""	""	""	""	"(2E)-3-[(4-methylbenzene)sulfonyl]prop-2-enenitrile"	""	"(E)-3-tosylacrylonitrile|BAY-117082|BAY117082"	"N#C/C=C/S(=O)(=O)c1ccc(cc1)C"	"DOEWDSDBFRHVAP-KRXBUXKQSA-N"	"InChI=1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+"	"yes"	""	""
"13101"	"BAY1830839"	""	"Synthetic organic"	""	""	""	""	"491299883"	"121364971"	""	""	"CHEMBL4782801"	""	""	""	""	"N-[2-(3-hydroxy-3-methylbutyl)-6-(2-hydroxypropan-2-yl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide"	""	"BAY-1830839|example 11 [WO2016083433A1]"	"CC(C)(O)CCN1C=C2C=C(NC(=O)C=3C=CC=C(N3)C(F)(F)F)C(=CC2=N1)C(C)(C)O"	"NWFPCWIBSBZRGV-UHFFFAOYSA-N"	"InChI=1S/C22H25F3N4O3/c1-20(2,31)8-9-29-12-13-10-17(14(21(3,4)32)11-16(13)28-29)27-19(30)15-6-5-7-18(26-15)22(23,24)25/h5-7,10-12,31-32H,8-9H2,1-4H3,(H,27,30)"	"yes"	""	""
"10597"	"BAY-985"	""	"Synthetic organic"	""	""	""	""	"404859044"	"145925685"	""	""	""	""	""	""	""	""	""	"BAY985|compound 34 [PMID: 31859507]"	"O=C(N1CCN(CC1)[C@@H](c1ccnc(c1)Nc1nc2c([nH]1)cc(cc2)c1ncnc(c1)N(C)C)C)CC(F)(F)F"	"HZRJHVDNTDBTOZ-QGZVFWFLSA-N"	"InChI=1S/C27H30F3N9O/c1-17(38-8-10-39(11-9-38)25(40)15-27(28,29)30)18-6-7-31-23(13-18)36-26-34-20-5-4-19(12-22(20)35-26)21-14-24(37(2)3)33-16-32-21/h4-7,12-14,16-17H,8-11,15H2,1-3H3,(H2,31,34,35,36)/t17-/m1/s1"	"yes"	""	""
"3381"	"BAYu9773"	""	"Synthetic organic"	""	""	""	""	"178100399"	"5311015"	""	""	"CHEMBL285954"	""	""	""	""	"4-{[(4S,5R,6E,8E,10Z,13Z)-1-carboxy-4-hydroxynonadeca-6,8,10,13-tetraen-5-yl]sulfanyl}benzoic acid"	""	"BAY u9773|BAY-u 9773"	"CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)Sc1ccc(cc1)C(=O)O"	"PKJINWOACFYDQN-RBVMPENBSA-N"	"InChI=1S/C27H36O5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-25(24(28)15-14-17-26(29)30)33-23-20-18-22(19-21-23)27(31)32/h6-7,9-13,16,18-21,24-25,28H,2-5,8,14-15,17H2,1H3,(H,29,30)(H,31,32)/b7-6-,10-9-,12-11+,16-13+/t24-,25+/m0/s1"	"yes"	""	""
"12671"	"BC-1215"	""	"Synthetic organic"	""	""	""	""	"483123219"	"72201045"	""	""	"CHEMBL4549895"	""	""	""	""	"N,N'-bis[(4-pyridin-2-ylphenyl)methyl]ethane-1,2-diamine"	""	"BC 1215|BC1215"	"C1=CC=NC(=C1)C2=CC=C(C=C2)CNCCNCC3=CC=C(C=C3)C4=CC=CC=N4"	"IXEPQJQQSLMESJ-UHFFFAOYSA-N"	"InChI=1S/C26H26N4/c1-3-15-29-25(5-1)23-11-7-21(8-12-23)19-27-17-18-28-20-22-9-13-24(14-10-22)26-6-2-4-16-30-26/h1-16,27-28H,17-20H2"	"yes"	""	""
"7059"	"beclometasone"	""	"Synthetic organic"	"yes"	""	""	""	"178103638"	"20469"	""	""	"CHEMBL1586"	""	""	""	""	"(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one"	"beclometasone"	"beclomethasone|SCH-18020W"	"OCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)Cl"	"NBMKJKDGKREAPL-DVTGEIKXSA-N"	"InChI=1S/C22H29ClO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1"	"yes"	""	""
"5894"	"beclometasone dipropionate"	""	"Synthetic organic"	"yes"	""	""	""	"178102517"	"21700"	""	""	"CHEMBL1200500"	""	""	""	""	"[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-(2-propanoyloxyacetyl)-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate"	""	"beclomethasone dipropionate|Beconase&reg;|Qnasl&reg;|Vancenase&reg;"	"CCC(=O)O[C@@]1([C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)Cl)C(=O)COC(=O)CC"	"KUVIULQEHSCUHY-XYWKZLDCSA-N"	"InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1"	"yes"	""	""
"8691"	"begelomab"	""	"Antibody"	""	""	""	""	"252166891"	""	""	""	""	""	""	""	""	""	"begelomab"	"Begendina&rg; (proprietary name)|BT 5/9|SAND 26"	""	""	""	"yes"	""	""
"11117"	"belantamab mafodotin"	""	"Antibody"	"yes"	"yes"	""	""	"434122177"	""	""	""	""	""	""	""	""	""	"belantamab mafodotin"	"belamaf|belantamab mafodotin-blmf|Blenrep&reg;|GSK-2857916|GSK2857916"	""	""	""	"yes"	""	""
"6892"	"belatacept"	""	"Peptide"	"yes"	""	""	""	"178103474"	""	""	""	"CHEMBL1742990"	""	""	""	""	""	"belatacept"	"BMS-224818|LEA29Y|Nulojix&reg;"	""	""	""	"yes"	""	""
"6887"	"belimumab"	""	"Antibody"	"yes"	""	""	""	"178103469"	""	""	""	""	""	""	""	""	""	"belimumab"	"Benlysta&reg;|hBlySmAb-1.1|LimphoStat-B|lymphostat-B"	""	""	""	"yes"	""	""
"9035"	"belnacasan"	""	"Synthetic organic"	""	""	""	""	"315661120"	"11398092"	""	""	""	""	""	""	""	"(2S)-1-[(2S)-2-[(4-amino-3-chlorobenzoyl)amino]-3,3-dimethylbutanoyl]-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]pyrrolidine-2-carboxamide"	""	"HMR3480|VX-765"	"CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)(C)C)NC(=O)c1ccc(c(c1)Cl)N"	"SJDDOCKBXFJEJB-MOKWFATOSA-N"	"InChI=1S/C24H33ClN4O6/c1-5-34-23-16(12-18(30)35-23)27-21(32)17-7-6-10-29(17)22(33)19(24(2,3)4)28-20(31)13-8-9-15(26)14(25)11-13/h8-9,11,16-17,19,23H,5-7,10,12,26H2,1-4H3,(H,27,32)(H,28,31)/t16-,17-,19+,23+/m0/s1"	"yes"	""	""
"9558"	"belumosudil"	""	"Synthetic organic"	"yes"	""	""	""	"336446944"	"11950170"	""	""	"CHEMBL2005186"	""	""	""	""	"2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide"	""	"KD-025|KD025|Rezurock&reg;|SLx 2119|SLx2119"	"CC(NC(=O)COc1cccc(c1)c1nc(Nc2ccc3c(c2)cn[nH]3)c2c(n1)cccc2)C"	"GKHIVNAUVKXIIY-UHFFFAOYSA-N"	"InChI=1S/C26H24N6O2/c1-16(2)28-24(33)15-34-20-7-5-6-17(13-20)25-30-23-9-4-3-8-21(23)26(31-25)29-19-10-11-22-18(12-19)14-27-32-22/h3-14,16H,15H2,1-2H3,(H,27,32)(H,28,33)(H,29,30,31)"	"yes"	""	""
"10659"	"bempegaldesleukin"	""	"Peptide"	""	""	""	""	"404859106"	""	""	""	""	""	""	""	""	""	"bempegaldesleukin"	"NKTR-214|NKTR214"	""	""	""	"yes"	""	""
"13725"	"bempikibart"	""	"Antibody"	""	""	""	""	"507750359"	""	""	""	""	""	""	""	""	""	"bempikibart"	"ADX-914|ADX914"	""	""	""	"yes"	""	""
"7674"	"benralizumab"	""	"Antibody"	"yes"	""	""	""	"223366009"	""	""	""	"CHEMBL1742991"	""	""	""	""	""	"benralizumab"	"BIW-8405|Fasenra&reg;|KHK4563|MEDI-563"	""	""	""	"yes"	""	""
"9926"	"bentamapimod"	""	"Synthetic organic"	""	""	""	""	"363894220"	"10195250"	""	""	"CHEMBL3545213"	""	""	""	""	""	"bentamapimod"	"AS-602801|AS602801|PGL-5001|PGL5001"	"N#CC(c1nc2c(s1)cccc2)c1ccnc(n1)OCc1ccc(cc1)CN1CCOCC1"	"XCPPIJCBCWUBNT-UHFFFAOYSA-N"	"InChI=1S/C25H23N5O2S/c26-15-20(24-28-22-3-1-2-4-23(22)33-24)21-9-10-27-25(29-21)32-17-19-7-5-18(6-8-19)16-30-11-13-31-14-12-30/h1-10,20H,11-14,16-17H2"	"yes"	""	""
"9731"	"benzodrocortisone"	""	"Synthetic organic"	""	""	""	""	"354702207"	"119845"	""	""	""	""	""	""	""	"[(8S,9S,10R,11S,13S,14S,17R)-11-hydroxy-17-(2-hydroxy-acetyl)-10,13-dimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-17-yl] benzoate"	"benzodrocortisone"	"compound 1 [WO2013071010]|hydrocortisone 17-benzoate"	"OCC(=O)[C@]1(CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C)OC(=O)c1ccccc1"	"LPEYMYDYPGRLBU-YGZHYJPASA-N"	"InChI=1S/C28H34O6/c1-26-12-10-19(30)14-18(26)8-9-20-21-11-13-28(23(32)16-29,27(21,2)15-22(31)24(20)26)34-25(33)17-6-4-3-5-7-17/h3-7,14,20-22,24,29,31H,8-13,15-16H2,1-2H3/t20-,21-,22-,24+,26-,27-,28-/m0/s1"	"yes"	""	""
"14536"	"berzanoflast"	""	"Synthetic organic"	""	""	""	""	""	"166456099"	""	""	""	""	""	""	""	"(2S)-3-[[4-[2-hydroxy-4-(trifluoromethyl)phenyl]phthalazin-1-yl]amino]propane-1,2-diol"	"berzanoflast"	"AZD-4144|AZD4144|compound 25 [PMID: 40631926]"	"C1=CC=C2C(=C1)C(=NN=C2NC[C@@H](CO)O)C3=C(C=C(C=C3)C(F)(F)F)O"	"CEGVLCNHZDUFIJ-NSHDSACASA-N"	"InChI=1S/C18H16F3N3O3/c19-18(20,21)10-5-6-14(15(27)7-10)16-12-3-1-2-4-13(12)17(24-23-16)22-8-11(26)9-25/h1-7,11,25-27H,8-9H2,(H,22,24)/t11-/m0/s1"	"yes"	""	""
"7061"	"betamethasone"	""	"Metabolite"	"yes"	""	""	""	"178103640"	"9782"	""	""	"CHEMBL632"	""	""	""	""	"(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one"	"betamethasone"	"SCH-4831"	"OCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F"	"UREBDLICKHMUKA-DVTGEIKXSA-N"	"InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1"	"yes"	""	""
"12907"	"bexmarilimab"	""	"Antibody"	""	""	""	""	"485206028"	""	""	""	""	""	""	""	""	""	"bexmarilimab"	"Clevegen|FP-1305|FP1305"	""	""	""	"yes"	""	""
"12898"	"bexobrutideg"	""	"Synthetic organic"	""	""	""	""	"485206019"	"156464216"	""	""	""	""	""	""	""	"3-[4-[1-[[1-[6-[[(3S)-2,6-dioxopiperidin-3-yl]carbamoyl]pyridin-3-yl]piperidin-4-yl]methyl]piperidin-4-yl]anilino]-5-[(3R)-3-(3-methyl-2-oxoimidazolidin-1-yl)piperidin-1-yl]pyrazine-2-carboxamide"	"bexobrutideg"	"compound 195 [WO2021113557A1]|NX-5948|NX5948"	"CN1CCN([C@@H]2CCCN(C2)C3=NC(NC4=CC=C(C=C4)C5CCN(CC6CCN(CC6)C7=CN=C(C=C7)C(=O)N[C@H]8CCC(=O)NC8=O)CC5)=C(N=C3)C(N)=O)C1=O"	"HPTPDBYCFHFWJG-CWTKIQHKSA-N"	"InChI=1S/C42H54N12O5/c1-50-21-22-54(42(50)59)32-3-2-16-53(26-32)35-24-45-37(38(43)56)39(48-35)46-30-6-4-28(5-7-30)29-14-17-51(18-15-29)25-27-12-19-52(20-13-27)31-8-9-33(44-23-31)40(57)47-34-10-11-36(55)49-41(34)58/h4-9,23-24,27,29,32,34H,2-3,10-22,25-26H2,1H3,(H2,43,56)(H,46,48)(H,47,57)(H,49,55,58)/t32-,34+/m1/s1"	"yes"	""	""
"13988"	"bezisterim"	""	"Synthetic organic"	""	""	""	""	"518520615"	"16739648"	""	""	"CHEMBL4297284"	""	""	""	""	"(3S,7R,8R,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-3,7,17-triol"	"bezisterim"	"17-ethynyl-5-androstene-3,7,17-triol|HE-3286|HE3286|NE-3107|NE3107"	"C[C@]12CC[C@@H](CC1=C[C@@H]([C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@]4(C#C)O)C)O)O"	"JJKOQZHWYLMASZ-FJWDNACWSA-N"	"InChI=1S/C21H30O3/c1-4-21(24)10-7-16-18-15(6-9-20(16,21)3)19(2)8-5-14(22)11-13(19)12-17(18)23/h1,12,14-18,22-24H,5-11H2,2-3H3/t14-,15-,16-,17-,18+,19-,20-,21-/m0/s1"	"yes"	""	""
"9717"	"BI-1935"	""	"Synthetic organic"	""	""	""	""	"348353676"	"57861407"	""	""	""	""	""	""	""	"1-(2-ethoxyethyl)-6-oxo-N-[5-[3-pyridin-3-yl-5-(trifluoromethyl)pyrazol-1-yl]pyridin-2-yl]pyridine-3-carboxamide"	""	"BI 1935|example 3 [WO2007067836]"	"CCOCCn1cc(ccc1=O)C(=O)Nc1ccc(cn1)n1nc(cc1C(F)(F)F)c1cccnc1"	"KMESAVNRPDKZCQ-UHFFFAOYSA-N"	"InChI=1S/C24H21F3N6O3/c1-2-36-11-10-32-15-17(5-8-22(32)34)23(35)30-21-7-6-18(14-29-21)33-20(24(25,26)27)12-19(31-33)16-4-3-9-28-13-16/h3-9,12-15H,2,10-11H2,1H3,(H,29,30,35)"	"yes"	""	""
"9719"	"BI-1950"	""	"Synthetic organic"	""	""	""	""	"348353678"	"58431184"	""	""	""	""	""	""	""	"(2S)-2-{[(3R)-3-[(4-cyanophenyl)methyl]-1-(3,5-dichloro-4-fluorophenyl)-3-methyl-2-oxo-1H,2H,3H-[1,3]diazolo[1,2-a]imidazol-5-yl]formamido}-N-[1-(pyridin-2-yl)cyclopropyl]propanamide"	""	""	"N#Cc1ccc(cc1)C[C@]1(C)C(=O)N(c2n1c(cn2)C(=O)N[C@H](C(=O)NC1(CC1)c1ccccn1)C)c1cc(Cl)c(c(c1)Cl)F"	"JZTTUZXIQIRVAB-FZEVHQGJSA-N"	"InChI=1S/C32H26Cl2FN7O3/c1-18(27(43)40-32(10-11-32)25-5-3-4-12-37-25)39-28(44)24-17-38-30-41(21-13-22(33)26(35)23(34)14-21)29(45)31(2,42(24)30)15-19-6-8-20(16-36)9-7-19/h3-9,12-14,17-18H,10-11,15H2,1-2H3,(H,39,44)(H,40,43)/t18-,31+/m0/s1"	"yes"	""	""
"9791"	"BI-2545"	""	"Synthetic organic"	""	""	""	""	"354702264"	"131953432"	""	""	""	""	""	""	""	"[3,5-bis(trifluoromethyl)phenyl]methyl (1R,5S,6S)-6-{[(1H-1,2,3-benzotriazol-5-yl)formamido]methyl}-3-azabicyclo[3.1.0]hexane-3-carboxylate"	""	"BI2545|compound 19 [PMID: 29259743]"	"O=C(N1C[C@@H]2[C@H](C1)[C@@H]2CNC(=O)c1ccc2c(c1)nn[nH]2)OCc1cc(cc(c1)C(F)(F)F)C(F)(F)F"	"ZDOBSAPHUUUOHX-BJWYYQGGSA-N"	"InChI=1S/C23H19F6N5O3/c24-22(25,26)13-3-11(4-14(6-13)23(27,28)29)10-37-21(36)34-8-16-15(17(16)9-34)7-30-20(35)12-1-2-18-19(5-12)32-33-31-18/h1-6,15-17H,7-10H2,(H,30,35)(H,31,32,33)/t15-,16+,17-"	"yes"	""	""
"9357"	"BI605906"	""	"Synthetic organic"	""	""	""	""	"328083459"	"23652660"	""	""	""	""	""	""	""	"3-amino-4-(1,1-difluoropropyl)-6-(4-methylsulfonylpiperidin-1-yl)thieno[5,4-b]pyridine-2-carboxamide"	""	"3-Amino-4-(1,1-difluoro- propyl)-6-(4-methanesulfonyl- piperidin-1-yl)-thieno[2,3- b]pyridine-2-carboxylic acid amide|compound 115 [US20070293533]"	"CCC(c1cc(nc2c1c(N)c(s2)C(=O)N)N1CCC(CC1)S(=O)(=O)C)(F)F"	"IYHHRZBKXXKDDY-UHFFFAOYSA-N"	"InChI=1S/C17H22F2N4O3S2/c1-3-17(18,19)10-8-11(23-6-4-9(5-7-23)28(2,25)26)22-16-12(10)13(20)14(27-16)15(21)24/h8-9H,3-7,20H2,1-2H3,(H2,21,24)"	"yes"	""	""
"9715"	"BI 653048"	""	"Synthetic organic"	""	""	""	""	"348353674"	"44543970"	""	""	"CHEMBL3358954"	""	""	""	""	"(R)-2-(4-((5-(Ethylsulfonyl)-1H-pyrrolo[2,3-c]pyridin-2-yl)methyl)-5,5,5-trifluoro-4-hydroxy-2-methylpentan-2-yl)-5-fluorobenzamide"	""	"(R)-39|BI 653048 BS H3PO4|BI-653048|BI653048"	"CCS(=O)(=O)c1ncc2c(c1)cc([nH]2)C[C@@](C(F)(F)F)(CC(c1ccc(cc1C(=O)N)F)(C)C)O"	"AUIFRJWXYUNPPV-QFIPXVFZSA-N"	"InChI=1S/C23H25F4N3O4S/c1-4-35(33,34)19-8-13-7-15(30-18(13)11-29-19)10-22(32,23(25,26)27)12-21(2,3)17-6-5-14(24)9-16(17)20(28)31/h5-9,11,30,32H,4,10,12H2,1-3H3,(H2,28,31)/t22-/m0/s1"	"yes"	""	""
"9716"	"BI 665915"	""	"Synthetic organic"	""	""	""	""	"348353675"	"66765019"	""	""	""	""	""	""	""	"2-[4-(3-{1-[4-(2-aminopyrimidin-5-yl)phenyl]-1-cyclopropylethyl}-1,2,4-oxadiazol-5-yl)-1H-pyrazol-1-yl]-N,N-dimethylacetamide"	""	"BI-665915|compound 69 [PMID: 25671290]"	"O=C(N(C)C)Cn1ncc(c1)c1onc(n1)C(c1ccc(cc1)c1cnc(nc1)N)(C1CC1)C"	"QGPXEIMWTKWHMH-UHFFFAOYSA-N"	"InChI=1S/C24H26N8O2/c1-24(19-8-9-19,18-6-4-15(5-7-18)16-10-26-23(25)27-11-16)22-29-21(34-30-22)17-12-28-32(13-17)14-20(33)31(2)3/h4-7,10-13,19H,8-9,14H2,1-3H3,(H2,25,26,27)"	"yes"	""	""
"9714"	"BI-6901"	""	"Synthetic organic"	""	""	""	""	"348353673"	"131801164"	""	""	""	""	""	""	""	"4-(2-cyano-1H-pyrrol-1-yl)-S-(1H-indol-4-yl)-1-(4-methylpiperidin-1-yl)-1-oxobutane-2-sulfonamido"	""	"BI 6901|BI6901|eut-22"	"N#Cc1cccn1CC[C@H](C(=O)N1CCC(CC1)C)NS(=O)(=O)c1cccc2c1cc[nH]2"	"BRJXJOWXAFLRTE-OAQYLSRUSA-N"	"InChI=1S/C23H27N5O3S/c1-17-8-13-28(14-9-17)23(29)21(10-15-27-12-3-4-18(27)16-24)26-32(30,31)22-6-2-5-20-19(22)7-11-25-20/h2-7,11-12,17,21,25-26H,8-10,13-15H2,1H3/t21-/m1/s1"	"yes"	""	""
"9756"	"bifikafusp alfa"	""	"Antibody"	""	""	""	""	"354702229"	""	""	""	""	""	""	""	""	""	"bifikafusp alfa"	"Daramun (bifikafusp alfa and onfekafusp alfa)|Darleukin|L19-IL2|L19IL2|Nidlegy (bifikafusp alfa and onfekafusp alfa)"	""	""	""	"yes"	""	""
"9183"	"bihelical apoA-I mimetic peptide 5A"	""	"Peptide"	""	""	""	""	"315661263"	"121231406"	""	""	""	""	""	""	""	""	""	"5A peptide"	"[NH3]CCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C)C)CCC(=O)O)CCCC[NH3])C)CCCC[NH3])CCC(=O)O)C)C)CCCC[NH3])CC(=O)O)Cc1ccc(cc1)O)C)C)CCCC[NH3])C)Cc1c[nH]c2c1cccc2)CC(=O)O)Cc1ccccc1)C)CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](CC(=O)O)N)CC(C)C)CCCC[NH3])C)Cc1ccccc1)Cc1ccc(cc1)O)CC(=O)O)CCCC[NH3])C)CCC(=O)O)CCCC[NH3])CC(C)C"	"FOIYDQXBMQZAML-GNGNDROBSA-N"	"InChI=1S/C197H303N47O56/c1-101(2)87-140(235-180(282)134(59-34-42-84-204)225-182(284)139(73-77-155(253)254)223-167(269)113(16)218-195(297)160(103(5)6)243-183(285)135(60-35-43-85-205)229-192(294)148(97-158(259)260)240-189(291)144(91-118-64-68-122(246)69-65-118)237-187(289)142(89-115-45-20-18-21-46-115)232-169(271)111(14)215-175(277)130(55-30-38-80-200)226-186(288)141(88-102(3)4)236-190(292)146(234-171(273)125(206)95-156(255)256)94-120-100-208-127-52-27-25-50-124(120)127)185(287)228-133(58-33-41-83-203)179(281)231-137(71-75-153(249)250)177(279)216-112(15)170(272)242-150(92-116-47-22-19-23-48-116)196(298)244-86-44-61-151(244)194(296)241-149(98-159(261)262)193(295)238-145(93-119-99-207-126-51-26-24-49-123(119)126)184(286)217-110(13)166(268)220-128(53-28-36-78-198)172(274)211-104(7)162(264)210-108(11)168(270)233-143(90-117-62-66-121(245)67-63-117)188(290)239-147(96-157(257)258)191(293)227-131(56-31-39-81-201)174(276)212-105(8)161(263)209-107(10)164(266)222-138(72-76-154(251)252)181(283)224-129(54-29-37-79-199)173(275)214-109(12)165(267)221-132(57-32-40-82-202)178(280)230-136(70-74-152(247)248)176(278)213-106(9)163(265)219-114(17)197(299)300/h18-27,45-52,62-69,99-114,125,128-151,160,207-208,245-246H,28-44,53-61,70-98,206H2,1-17,198-205H3,(H,209,263)(H,210,264)(H,211,274)(H,212,276)(H,213,278)(H,214,275)(H,215,277)(H,216,279)(H,217,286)(H,218,297)(H,219,265)(H,220,268)(H,221,267)(H,222,266)(H,223,269)(H,224,283)(H,225,284)(H,226,288)(H,227,293)(H,228,287)(H,229,294)(H,230,280)(H,231,281)(H,232,271)(H,233,270)(H,234,273)(H,235,282)(H,236,292)(H,237,289)(H,238,295)(H,239,290)(H,240,291)(H,241,296)(H,242,272)(H,243,285)(H,247,248)(H,249,250)(H,251,252)(H,253,254)(H,255,256)(H,257,258)(H,259,260)(H,261,262)(H,299,300)/t104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,125-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,151-,160-/m0/s1"	"yes"	""	""
"11178"	"BIIB068"	""	"Synthetic organic"	""	""	""	""	"434122238"	"118139356"	""	""	""	""	""	""	""	"N-[[2-methyl-4-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]phenyl]methyl]-3-propan-2-yloxyazetidine-1-carboxamide"	""	"BIIB-068|compound 1 [PMID: 32696648]"	"CC(OC1CN(C1)C(=O)NCc1ccc(cc1C)c1ccnc(n1)Nc1cnn(c1)C)C"	"BMWMKGNVAMXXCH-UHFFFAOYSA-N"	"InChI=1S/C23H29N7O2/c1-15(2)32-20-13-30(14-20)23(31)25-10-18-6-5-17(9-16(18)3)21-7-8-24-22(28-21)27-19-11-26-29(4)12-19/h5-9,11-12,15,20H,10,13-14H2,1-4H3,(H,25,31)(H,24,27,28)"	"yes"	""	""
"11791"	"BIIB091"	""	"Synthetic organic"	""	""	""	""	"458923826"	"135355941"	""	""	""	""	""	""	""	""	""	"BIIB-091|compound 51 [PMID: 34734694]"	"O=C(c1cn(C(C)(C)C)nn1)N[C@H]1c2ccc(c3ccnc(Nc4cn(C)nc4)n3)cc2CN(C2COC2)CC1"	"JSAQBOQCZJHWMA-XMMPIXPASA-N"	"InChI=1S/C28H34N10O2/c1-28(2,3)38-15-25(34-35-38)26(39)32-24-8-10-37(21-16-40-17-21)13-19-11-18(5-6-22(19)24)23-7-9-29-27(33-23)31-20-12-30-36(4)14-20/h5-7,9,11-12,14-15,21,24H,8,10,13,16-17H2,1-4H3,(H,32,39)(H,29,31,33)/t24-/m1/s1"	"yes"	""	""
"9411"	"bimekizumab"	""	"Antibody"	"yes"	""	""	""	"328083513"	""	""	""	""	""	""	""	""	""	"bimekizumab"	"bimekizumab-bkzx|Bimzelx&reg;|CA028_0496|CDP4940|gL7gH9|UCB-4940|UCB4940|Zu-G1"	""	""	""	"yes"	""	""
"9049"	"bimosiamose"	""	"Synthetic organic"	""	""	""	""	"315661134"	"9811353"	""	""	"CHEMBL1215923"	""	""	""	""	"2-[3-[5-[6-[3-[3-(carboxymethyl)phenyl]-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]hexyl]-2-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]phenyl]acetic acid"	"bimosiamose"	"compound 15e [PMID: 9544210]|TBC 1269|TBC-1269|TBC1269"	"OC[C@H]1O[C@H](Oc2ccc(cc2c2cccc(c2)CC(=O)O)CCCCCCc2ccc(c(c2)c2cccc(c2)CC(=O)O)O[C@H]2O[C@H](CO)[C@H]([C@@H]([C@@H]2O)O)O)[C@H]([C@H]([C@@H]1O)O)O"	"RYWCQJDEHXJHRI-XJMXIVSISA-N"	"InChI=1S/C46H54O16/c47-23-35-39(53)41(55)43(57)45(61-35)59-33-15-13-25(19-31(33)29-11-5-9-27(17-29)21-37(49)50)7-3-1-2-4-8-26-14-16-34(60-46-44(58)42(56)40(54)36(24-48)62-46)32(20-26)30-12-6-10-28(18-30)22-38(51)52/h5-6,9-20,35-36,39-48,53-58H,1-4,7-8,21-24H2,(H,49,50)(H,51,52)/t35-,36-,39-,40-,41+,42+,43+,44+,45+,46+/m1/s1"	"yes"	""	""
"11124"	"bindarit"	""	"Synthetic organic"	""	""	""	""	"434122184"	"71354"	""	""	"CHEMBL2107549"	""	""	""	""	"2-[(1-benzylindazol-3-yl)methoxy]-2-methylpropanoic acid"	"bindarit"	"AF-2838|AF2838"	"OC(=O)C(OCc1nn(c2c1cccc2)Cc1ccccc1)(C)C"	"MTHORRSSURHQPZ-UHFFFAOYSA-N"	"InChI=1S/C19H20N2O3/c1-19(2,18(22)23)24-13-16-15-10-6-7-11-17(15)21(20-16)12-14-8-4-3-5-9-14/h3-11H,12-13H2,1-2H3,(H,22,23)"	"yes"	""	""
"11376"	"bintrafusp alfa"	""	"Antibody"	""	""	""	""	"440816745"	""	""	""	""	""	""	""	""	""	"bintrafusp alfa"	"M7824|MSB0011359C"	""	""	""	"yes"	""	""
"13341"	"BIO-7488"	""	"Synthetic organic"	""	""	""	""	"496703311"	"155437283"	""	""	""	""	""	""	""	"2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)-7-propan-2-yloxyimidazo[1,2-a]pyrimidine-6-carboxamide"	""	"BIO7488"	"CC1=CN2C(=C(C=N2)NC(=O)C3=CN4C=C(N=C4N=C3OC(C)C)C56CC(C5)(OC6)C)N=C1"	"DEQCXGYERMCXNL-UHFFFAOYSA-N"	"InChI=1S/C23H25N7O3/c1-13(2)33-20-15(19(31)26-16-6-25-30-7-14(3)5-24-18(16)30)8-29-9-17(27-21(29)28-20)23-10-22(4,11-23)32-12-23/h5-9,13H,10-12H2,1-4H3,(H,26,31)"	"yes"	""	""
"13355"	"BIO-8169"	""	"Synthetic organic"	""	""	""	""	"496703325"	"164554747"	""	""	""	""	""	""	""	"N-(1-cyclopropyl-2-oxopyridin-3-yl)-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-7-propan-2-yloxyimidazo[1,2-a]pyrimidine-6-carboxamide"	""	"BIO8169|compound 2 [PMID: 38695469]"	"CC(C)OC1=NC2=NC(C34COC(C3)(C)C4)=CN2C=C1C(NC5=CC=CN(C6CC6)C5=O)=O"	"JJZLDWBCAMPSMG-UHFFFAOYSA-N"	"InChI=1S/C24H27N5O4/c1-14(2)33-20-16(19(30)25-17-5-4-8-29(21(17)31)15-6-7-15)9-28-10-18(26-22(28)27-20)24-11-23(3,12-24)32-13-24/h4-5,8-10,14-15H,6-7,11-13H2,1-3H3,(H,25,30)"	"yes"	""	""
"9720"	"BIRT 377"	""	"Synthetic organic"	""	""	""	""	"348353679"	"9803375"	""	""	"CHEMBL367808"	""	""	""	""	"(5R)-5-[(4-bromophenyl)methyl]-3-(3,5-dichlorophenyl)-1,5-dimethylimidazolidine-2,4-dione"	""	"BIRT-377"	"Brc1ccc(cc1)C[C@@]1(C)N(C)C(=O)N(C1=O)c1cc(Cl)cc(c1)Cl"	"FJNJHZQMQRVZEE-GOSISDBHSA-N"	"InChI=1S/C18H15BrCl2N2O2/c1-18(10-11-3-5-12(19)6-4-11)16(24)23(17(25)22(18)2)15-8-13(20)7-14(21)9-15/h3-9H,10H2,1-2H3/t18-/m1/s1"	"yes"	""	""
"7384"	"blinatumomab"	""	"Antibody"	"yes"	""	""	""	"178103956"	""	""	""	""	""	""	""	""	""	"blinatumomab"	"Blincyto&reg;|bscCD19xCD3|MEDI-538|MT-103|MT103"	""	""	""	"yes"	""	""
"9518"	"blisibimod"	""	"Peptide"	""	""	""	""	"336446905"	""	""	""	""	""	""	""	""	""	"blisibimod"	"A-623|AGP3 peptibody|AMG 623|Fc-Agp-3"	""	""	""	"yes"	""	""
"9664"	"BML-281"	""	"Synthetic organic"	""	""	""	""	"348353623"	"24951314"	""	""	"CHEMBL511749"	""	""	""	""	"tert-butyl N-[4-[3-[[7-(hydroxyamino)-7-oxoheptyl]carbamoyl]-1,2-oxazol-5-yl]phenyl]carbamate"	""	"compound 3 [PMID: 18642892]"	"ONC(=O)CCCCCCNC(=O)c1noc(c1)c1ccc(cc1)NC(=O)OC(C)(C)C"	"WWGBHDIHIVGYLZ-UHFFFAOYSA-N"	"InChI=1S/C22H30N4O6/c1-22(2,3)31-21(29)24-16-11-9-15(10-12-16)18-14-17(26-32-18)20(28)23-13-7-5-4-6-8-19(27)25-30/h9-12,14,30H,4-8,13H2,1-3H3,(H,23,28)(H,24,29)(H,25,27)"	"yes"	""	""
"10191"	"BMS-1001"	""	"Synthetic organic"	""	""	""	""	"381118901"	"118435188"	""	""	""	""	""	""	""	""	""	"BMS1001|Example 1001 [WO2015160641A2]"	"OCC(C(=O)O)NCc1cc(C)c(cc1OCc1cccc(c1)C#N)OCc1cccc(c1C)c1ccc2c(c1)OCCO2"	"UWNXGZKSIKQKAH-UHFFFAOYSA-N"	"InChI=1S/C35H34N2O7/c1-22-13-28(18-37-30(19-38)35(39)40)33(43-20-25-6-3-5-24(14-25)17-36)16-32(22)44-21-27-7-4-8-29(23(27)2)26-9-10-31-34(15-26)42-12-11-41-31/h3-10,13-16,30,37-38H,11-12,18-21H2,1-2H3,(H,39,40)"	"yes"	""	""
"9608"	"BMS-1166"	""	"Synthetic organic"	""	""	""	""	"340590238"	"118434635"	""	""	""	""	""	""	""	"(2R,4R)-1-[[5-chloro-2-[(3-cyanophenyl)methoxy]-4-[[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]methoxy]phenyl]methyl]-4-hydroxypyrrolidine-2-carboxylic acid"	""	"compound 2c [PMID: 28613862]|Example 1166 [WO2015160641A2]"	"N#Cc1cccc(c1)COc1cc(OCc2cccc(c2C)c2ccc3c(c2)OCCO3)c(cc1CN1C[C@@H](C[C@@H]1C(=O)O)O)Cl"	"QBXVXKRWOVBUDB-GRKNLSHJSA-N"	"InChI=1S/C36H33ClN2O7/c1-22-26(6-3-7-29(22)25-8-9-32-35(14-25)44-11-10-43-32)21-46-34-16-33(45-20-24-5-2-4-23(12-24)17-38)27(13-30(34)37)18-39-19-28(40)15-31(39)36(41)42/h2-9,12-14,16,28,31,40H,10-11,15,18-21H2,1H3,(H,41,42)/t28-,31-/m1/s1"	"yes"	""	""
"9607"	"BMS-202"	""	"Synthetic organic"	""	""	""	""	"340590237"	"117951478"	""	""	""	""	""	""	""	"N-[2-[[2-methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridin-3-yl]methylamino]ethyl]acetamide"	""	"compound 1c [PMID: 28613862]|PD1-PDL1 inhibitor 2"	"COc1nc(OCc2cccc(c2C)c2ccccc2)ccc1CNCCNC(=O)C"	"JEDPSOYOYVELLZ-UHFFFAOYSA-N"	"InChI=1S/C25H29N3O3/c1-18-22(10-7-11-23(18)20-8-5-4-6-9-20)17-31-24-13-12-21(25(28-24)30-3)16-26-14-15-27-19(2)29/h4-13,26H,14-17H2,1-3H3,(H,27,29)"	"yes"	""	""
"5669"	"BMS-345541"	""	"Synthetic organic"	""	""	""	""	"178102297"	"9813758"	""	""	"CHEMBL249697"	""	""	""	""	"N-(2-aminoethyl)-1,8-dimethylimidazo[1,2-a]quinoxalin-4-amine"	""	"BMS 345541|BMS345541"	"NCCNc1nc2ccc(cc2n2c1ncc2C)C"	"PSPFQEBFYXJZEV-UHFFFAOYSA-N"	"InChI=1S/C14H17N5/c1-9-3-4-11-12(7-9)19-10(2)8-17-14(19)13(18-11)16-6-5-15/h3-4,7-8H,5-6,15H2,1-2H3,(H,16,18)"	"yes"	""	""
"9994"	"BMS-509744"	""	"Synthetic organic"	""	""	""	""	"374883881"	"11467730"	""	""	"CHEMBL209148"	""	""	""	""	"N-[5-[5-(4-acetylpiperazine-1-carbonyl)-4-methoxy-2-methylphenyl]sulfanyl-1,3-thiazol-2-yl]-4-[(3,3-dimethylbutan-2-ylamino)methyl]benzamide"	""	"BMS 509744|BMS509744|compound 3 [PMID:16682193]"	"COc1cc(C)c(cc1C(=O)N1CCN(CC1)C(=O)C)Sc1cnc(s1)NC(=O)c1ccc(cc1)CNC(C(C)(C)C)C"	"ZHXNIYGJAOPMSO-UHFFFAOYSA-N"	"InChI=1S/C32H41N5O4S2/c1-20-16-26(41-7)25(30(40)37-14-12-36(13-15-37)22(3)38)17-27(20)42-28-19-34-31(43-28)35-29(39)24-10-8-23(9-11-24)18-33-21(2)32(4,5)6/h8-11,16-17,19,21,33H,12-15,18H2,1-7H3,(H,34,35,39)"	"yes"	""	""
"6509"	"BMS-561392"	""	"Synthetic organic"	""	""	""	""	"178103123"	"9847838"	""	""	"CHEMBL489100"	""	""	""	""	"(2R)-2-[(3R)-3-amino-3-[4-[(2-methylquinolin-4-yl)methoxy]phenyl]-2-oxopyrrolidin-1-yl]-N-hydroxy-4-methylpentanamide"	""	"BMS 561392|BMS561392|DPC-333"	"ONC(=O)[C@H](N1CC[C@@](C1=O)(N)c1ccc(cc1)OCc1cc(C)nc2c1cccc2)CC(C)C"	"QVNZBDLTUKCPGJ-SHQCIBLASA-N"	"InChI=1S/C27H32N4O4/c1-17(2)14-24(25(32)30-34)31-13-12-27(28,26(31)33)20-8-10-21(11-9-20)35-16-19-15-18(3)29-23-7-5-4-6-22(19)23/h4-11,15,17,24,34H,12-14,16,28H2,1-3H3,(H,30,32)/t24-,27-/m1/s1"	"yes"	""	""
"7838"	"BMS-582949"	""	"Synthetic organic"	""	""	""	""	"223366169"	"10409068"	""	""	"CHEMBL1230065"	""	""	""	""	"4-[[5-(cyclopropylcarbamoyl)-2-methylphenyl]amino]-5-methyl-N-propylpyrrolo[5,1-f][1,2,4]triazine-6-carboxamide"	""	"BMS 582949|BMS582949|PS 540446|PS-540446|PS540446"	"CCCNC(=O)c1cn2c(c1C)c(ncn2)Nc1cc(ccc1C)C(=O)NC1CC1"	"GDTQLZHHDRRBEB-UHFFFAOYSA-N"	"InChI=1S/C22H26N6O2/c1-4-9-23-22(30)17-11-28-19(14(17)3)20(24-12-25-28)27-18-10-15(6-5-13(18)2)21(29)26-16-7-8-16/h5-6,10-12,16H,4,7-9H2,1-3H3,(H,23,30)(H,26,29)(H,24,25,27)"	"yes"	""	""
"9430"	"BMS-681"	""	"Synthetic organic"	""	""	""	""	"328083530"	"68764898"	""	""	"CHEMBL3577945"	""	""	""	""	"(3S)-1-[(1S,2R,4R)-4-[methyl(propan-2-yl)amino]-2-propylcyclohexyl]-3-{[6-(trifluoromethyl)quinazolin-4-yl]amino}pyrrolidin-2-one"	""	"compound 13d [PMID: 25893046]"	"CCC[C@@H]1C[C@@H](CC[C@@H]1N1CC[C@@H](C1=O)Nc1ncnc2c1cc(cc2)C(F)(F)F)N(C(C)C)C"	"NUJWKQSEJDYCDB-GNRVTEMESA-N"	"InChI=1S/C26H36F3N5O/c1-5-6-17-13-19(33(4)16(2)3)8-10-23(17)34-12-11-22(25(34)35)32-24-20-14-18(26(27,28)29)7-9-21(20)30-15-31-24/h7,9,14-17,19,22-23H,5-6,8,10-13H2,1-4H3,(H,30,31,32)/t17-,19-,22+,23+/m1/s1"	"yes"	""	""
"9497"	"BMS-817399"	""	"Synthetic organic"	""	""	""	""	"336446899"	"44537841"	""	""	"CHEMBL3334824"	""	""	""	""	""	""	"compound 29 [PMID: 25101488]"	"O=C(CC(O)(C)C)N[C@@H](C(=O)N1CC[C@](C(C1)(C)C)(O)c1ccc(cc1)Cl)C(C)C"	"PTNKPLPRPJERNR-XXBNENTESA-N"	"InChI=1S/C23H35ClN2O4/c1-15(2)19(25-18(27)13-22(5,6)29)20(28)26-12-11-23(30,21(3,4)14-26)16-7-9-17(24)10-8-16/h7-10,15,19,29-30H,11-14H2,1-6H3,(H,25,27)/t19-,23+/m1/s1"	"yes"	""	""
"14079"	"BMS-852927"	""	"Synthetic organic"	""	""	""	""	"518520706"	"49787490"	""	""	"CHEMBL3945199"	""	""	""	""	"2-[2-[2-(2,6-dichlorophenyl)propan-2-yl]-1-[2-fluoro-4-[3-fluoro-4-(hydroxymethyl)-5-methylsulfonylphenyl]phenyl]imidazol-4-yl]propan-2-ol"	""	"BMS852927|compound 15 [PMID: 27994765]|XL-041|XL041"	"CC(C)(C1=CN(C(=N1)C(C)(C)C2=C(C=CC=C2Cl)Cl)C3=C(C=C(C=C3)C4=CC(=C(C(=C4)S(=O)(=O)C)CO)F)F)O"	"HNAJDMYOTDNOBK-UHFFFAOYSA-N"	"InChI=1S/C29H28Cl2F2N2O4S/c1-28(2,26-19(30)7-6-8-20(26)31)27-34-25(29(3,4)37)14-35(27)23-10-9-16(11-22(23)33)17-12-21(32)18(15-36)24(13-17)40(5,38)39/h6-14,36-37H,15H2,1-5H3"	"yes"	""	""
"11494"	"BMS-986104 derivative 12"	""	"Synthetic organic"	""	""	""	""	"440816862"	"118877241"	""	""	""	""	""	""	""	"[(1R,3S)-1-amino-3-[(6S)-6-(3-ethoxypropyl)-5,6,7,8-tetrahydronaphthalen-2-yl]cyclopentyl]methanol"	""	"compound 12 [PMID: 33492963]"	"CCOCCC[C@@H]1CCc2c(C1)ccc(c2)[C@H]1CC[C@](C1)(N)CO"	"PYZTXDCPUPYILV-TYCQWZJGSA-N"	"InChI=1S/C21H33NO2/c1-2-24-11-3-4-16-5-6-18-13-19(8-7-17(18)12-16)20-9-10-21(22,14-20)15-23/h7-8,13,16,20,23H,2-6,9-12,14-15,22H2,1H3/t16-,20+,21-/m1/s1"	"yes"	""	""
"11495"	"BMS-986104 derivative 24"	""	"Synthetic organic"	""	""	""	""	"440816863"	"118877392"	""	""	""	""	""	""	""	"[(1R,3S)-1-amino-3-[(6S)-6-(5-methoxypentyl)-5,6,7,8-tetrahydronaphthalen-2-yl]cyclopentyl]methanol"	""	"compound 24 [PMID: 33492963]"	"COCCCCC[C@H]1CCc2c(C1)ccc(c2)[C@H]1CC[C@](C1)(N)CO"	"CMZZUAAIKUIMSG-BULFRSBZSA-N"	"InChI=1S/C22H35NO2/c1-25-12-4-2-3-5-17-6-7-19-14-20(9-8-18(19)13-17)21-10-11-22(23,15-21)16-24/h8-9,14,17,21,24H,2-7,10-13,15-16,23H2,1H3/t17-,21-,22+/m0/s1"	"yes"	""	""
"9857"	"BMS-986142"	""	"Synthetic organic"	""	""	""	""	"363894151"	"86582336"	""	""	""	""	""	""	""	"(7S)-3-fluoro-4-[3-(8-fluoro-1-methyl-2,4-dioxoquinazolin-3-yl)-2-methylphenyl]-7-(2-hydroxypropan-2-yl)-6,7,8,9-tetrahydro-5H-carbazole-1-carboxamide"	""	"BMS986142|compound 14f [PMID: 27583770]"	"Fc1cc(C(=O)N)c2c(c1c1cccc(c1C)n1c(=O)c3cccc(c3n(c1=O)C)F)c1CC[C@@H](Cc1[nH]2)C(O)(C)C"	"ZRYMMWAJAFUANM-INIZCTEOSA-N"	"InChI=1S/C32H30F2N4O4/c1-15-17(7-6-10-24(15)38-30(40)19-8-5-9-21(33)28(19)37(4)31(38)41)25-22(34)14-20(29(35)39)27-26(25)18-12-11-16(32(2,3)42)13-23(18)36-27/h5-10,14,16,36,42H,11-13H2,1-4H3,(H2,35,39)/t16-/m0/s1"	"yes"	""	""
"11493"	"BMS-986166"	""	"Synthetic organic"	""	""	""	""	"440816861"	"118877516"	""	""	""	""	""	""	""	"[(1R,3S)-1-amino-3-[(6S)-6-[2-(2-methoxyphenyl)ethyl]-5,6,7,8-tetrahydronaphthalen-2-yl]cyclopentyl]methanol"	""	"BMS986166|compound 14a [PMID: 30785748]"	"OC[C@@]1(N)CC[C@@H](C1)c1ccc2c(c1)CC[C@H](C2)CCc1ccccc1OC"	"QCMHGCDOZLWPOT-FMNCTDSISA-N"	"InChI=1S/C25H33NO2/c1-28-24-5-3-2-4-19(24)8-6-18-7-9-21-15-22(11-10-20(21)14-18)23-12-13-25(26,16-23)17-27/h2-5,10-11,15,18,23,27H,6-9,12-14,16-17,26H2,1H3/t18-,23+,25-/m1/s1"	"yes"	""	""
"11024"	"BMS-986235"	""	"Synthetic organic"	""	""	""	""	"405560465"	"122583088"	""	""	""	""	""	""	""	"1-[(3S,4R)-4-(2,6-difluoro-4-methoxyphenyl)-2-oxopyrrolidin-3-yl]-3-phenylurea"	""	"BMS986235|compound 13c [PMID: 32407089]|LAR-1219|LAR1219"	"COc1cc(F)c(c(c1)F)[C@@H]1CNC(=O)[C@H]1NC(=O)Nc1ccccc1"	"FJZNNKJZHQFMCK-LRDDRELGSA-N"	"InChI=1S/C18H17F2N3O3/c1-26-11-7-13(19)15(14(20)8-11)12-9-21-17(24)16(12)23-18(25)22-10-5-3-2-4-6-10/h2-8,12,16H,9H2,1H3,(H,21,24)(H2,22,23,25)/t12-,16-/m0/s1"	"yes"	""	""
"13877"	"BMS-986238"	""	"Peptide"	""	""	""	""	"513757562"	"172991800"	""	""	""	""	""	""	""	""	""	"BMS 986238|BMS986238"	"CCCC[C@H]1C(=O)N[C@H](C(=O)N[C@@H](CSCC(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)N2CCC[C@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)N3C[C@@H](C[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N([C@H](C(=O)N1C)CCCC)C)CC4=CN(C5=CC=CC=C54)CC(=O)O)CCN)CC6=CNC7=CC=CC=C76)O)CC(C)C)CN)CC(=O)N)C)C)CC8=CC=C(C=C8)O)C(=O)NCC(=O)N[C@@H](CC9=CN(N=N9)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O)C(=O)O)CC(C)C"	"IQRNUGWYTJONBD-LJOMSQDUSA-N"	"InChI=1S/C143H224N26O40S/c1-11-13-37-117-134(187)154-107(76-93(3)4)131(184)160-115(129(182)149-86-124(175)152-113(143(197)198)81-99-88-167(162-161-99)53-55-200-57-59-202-61-63-204-65-67-206-69-71-208-73-75-209-74-72-207-70-68-205-66-64-203-62-60-201-58-56-199-54-51-147-122(173)48-47-106(142(195)196)150-123(174)41-27-25-23-21-19-17-15-16-18-20-22-24-26-28-42-126(177)178)91-210-92-125(176)151-110(78-96-43-45-100(170)46-44-96)137(190)163(8)95(7)128(181)156-112(83-121(146)172)139(192)168-52-33-40-118(168)135(188)159-114(84-145)133(186)157-109(77-94(5)6)140(193)169-89-101(171)82-120(169)136(189)155-108(79-97-85-148-104-36-31-29-34-102(97)104)132(185)153-105(49-50-144)130(183)158-111(138(191)165(10)119(38-14-12-2)141(194)164(117)9)80-98-87-166(90-127(179)180)116-39-32-30-35-103(98)116/h29-32,34-36,39,43-46,85,87-88,93-95,101,105-115,117-120,148,170-171H,11-28,33,37-38,40-42,47-84,86,89-92,144-145H2,1-10H3,(H2,146,172)(H,147,173)(H,149,182)(H,150,174)(H,151,176)(H,152,175)(H,153,185)(H,154,187)(H,155,189)(H,156,181)(H,157,186)(H,158,183)(H,159,188)(H,160,184)(H,177,178)(H,179,180)(H,195,196)(H,197,198)/t95-,101+,105-,106-,107-,108-,109-,110-,111-,112-,113-,114-,115-,117-,118-,119-,120-/m0/s1"	"yes"	""	""
"10662"	"BMS-986260"	""	"Synthetic organic"	""	""	""	""	"404859109"	"122510453"	""	""	""	""	""	""	""	"6-[5-(3-chloro-4-fluorophenyl)-3-(2-hydroxyethyl)imidazol-4-yl]imidazo[1,2-b]pyridazine-3-carbonitrile"	""	"BMS986260|compound 10 [Velaparthi <i>et al</i>., 2020]|Example 32' [WO2016140884A1]"	"OCCn1cnc(c1c1ccc2n(n1)c(C#N)cn2)c1ccc(c(c1)Cl)F"	"VZZBCNXVZFAIQX-UHFFFAOYSA-N"	"InChI=1S/C18H12ClFN6O/c19-13-7-11(1-2-14(13)20)17-18(25(5-6-27)10-23-17)15-3-4-16-22-9-12(8-21)26(16)24-15/h1-4,7,9-10,27H,5-6H2"	"yes"	""	""
"14390"	"BMS-986331"	""	"Synthetic organic"	""	""	""	""	"523352182"	"139450967"	""	""	"CHEMBL5560494"	""	""	""	""	"1-(4-chloro-2-fluorophenyl)-3-[(3R)-1-[4-(2-dimethylphosphorylphenyl)-2,3-difluorophenyl]-2-oxopyrrolidin-3-yl]urea"	""	"BMS986331|compound 16 [PMID: 41701653]"	"CP(C)(=O)C1=CC=CC=C1C2=C(F)C(F)=C(C=C2)N3CC[C@@H](NC(=O)NC4=CC=C(Cl)C=C4F)C3=O"	"SFUBFHYGOVTFKX-LJQANCHMSA-N"	"InChI=1S/C25H22ClF3N3O3P/c1-36(2,35)21-6-4-3-5-15(21)16-8-10-20(23(29)22(16)28)32-12-11-19(24(32)33)31-25(34)30-18-9-7-14(26)13-17(18)27/h3-10,13,19H,11-12H2,1-2H3,(H2,30,31,34)/t19-/m1/s1"	"yes"	""	""
"14468"	"BMS-986482"	""	"Synthetic organic"	""	""	""	""	""	"172581346"	""	""	""	""	""	""	""	"3-[5-[4-(6-amino-4,5-dimethyl-2-pyridinyl)-2-fluorophenyl]-2-oxo-1,3-oxazol-3-yl]piperidine-2,6-dione"	""	"BMS986482|Example 1 [US12331045]"	"CC1=CC(=NC(=C1C)N)C2=CC(=C(C=C2)C3=CN(C(=O)O3)C4CCC(=O)NC4=O)F"	"PKEKMIKJWMHBLO-UHFFFAOYSA-N"	"InChI=1S/C21H19FN4O4/c1-10-7-15(24-19(23)11(10)2)12-3-4-13(14(22)8-12)17-9-26(21(29)30-17)16-5-6-18(27)25-20(16)28/h3-4,7-9,16H,5-6H2,1-2H3,(H2,23,24)(H,25,27,28)"	"yes"	""	""
"6391"	"bortezomib"	""	"Synthetic organic"	"yes"	""	""	""	"178103007"	"387447"	""	""	"CHEMBL325041"	""	""	""	""	"[(1R)-3-methyl-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]butyl]boronic acid"	"bortezomib"	"peptide boronate|PS-341|Velcade&reg;"	"CC(C[C@@H](B(O)O)NC(=O)[C@@H](NC(=O)c1cnccn1)Cc1ccccc1)C"	"GXJABQQUPOEUTA-RDJZCZTQSA-N"	"InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1"	"yes"	"yes"	""
"5710"	"bosutinib"	""	"Synthetic organic"	"yes"	""	""	""	"178102336"	"5328940"	""	""	"CHEMBL288441"	""	""	""	""	"4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline-3-carbonitrile"	"bosutinib"	"Bosulif&reg;|SK 606|SK-606|SKI 606"	"COc1cc2c(cc1OCCCN1CCN(CC1)C)ncc(c2Nc1cc(OC)c(cc1Cl)Cl)C#N"	"UBPYILGKFZZVDX-UHFFFAOYSA-N"	"InChI=1S/C26H29Cl2N5O3/c1-32-6-8-33(9-7-32)5-4-10-36-25-13-21-18(11-24(25)35-3)26(17(15-29)16-30-21)31-22-14-23(34-2)20(28)12-19(22)27/h11-14,16H,4-10H2,1-3H3,(H,30,31)"	"yes"	""	"yes"
"9869"	"branebrutinib"	""	"Synthetic organic"	""	""	""	""	"363894163"	"121293929"	""	""	""	""	""	""	""	"4-[(3S)-3-(but-2-ynoylamino)piperidin-1-yl]-5-fluoro-2,3-dimethyl-1H-indole-7-carboxamide"	"branebrutinib"	"BMS-986195|BMS986195|Example 223 [US20160115126A1]"	"CC#CC(=O)N[C@H]1CCCN(C1)c1c(F)cc(c2c1c(C)c([nH]2)C)C(=O)N"	"VJPPLCNBDLZIFG-ZDUSSCGKSA-N"	"InChI=1S/C20H23FN4O2/c1-4-6-16(26)24-13-7-5-8-25(10-13)19-15(21)9-14(20(22)27)18-17(19)11(2)12(3)23-18/h9,13,23H,5,7-8,10H2,1-3H3,(H2,22,27)(H,24,26)/t13-/m0/s1"	"yes"	""	""
"9293"	"brazikumab"	""	"Antibody"	""	""	""	""	"318164812"	""	""	""	""	""	""	""	""	""	"brazikumab"	"AMG 139|AMG-139|MEDI2070"	""	""	""	"yes"	""	""
"9412"	"brensocatib"	""	"Synthetic organic"	"yes"	""	""	""	"328083514"	"118253852"	""	""	""	""	""	""	""	"(2S)-N-[(1S)-1-cyano-2-[4-(3-methyl-2-oxo-1,3-benzoxazol-5-yl)phenyl]ethyl]-1,4-oxazepane-2-carboxamide"	"brensocatib"	"AZD7986|Brinsupri&reg;|compound 30|INS 1007|INS1007"	"N#C[C@H](Cc1ccc(cc1)c1ccc2c(c1)n(C)c(=O)o2)NC(=O)[C@@H]1CNCCCO1"	"AEXFXNFMSAAELR-RXVVDRJESA-N"	"InChI=1S/C23H24N4O4/c1-27-19-12-17(7-8-20(19)31-23(27)29)16-5-3-15(4-6-16)11-18(13-24)26-22(28)21-14-25-9-2-10-30-21/h3-8,12,18,21,25H,2,9-11,14H2,1H3,(H,26,28)/t18-,21-/m0/s1"	"yes"	""	""
"6772"	"brentuximab vedotin"	""	"Antibody"	"yes"	""	""	""	"178103378"	""	""	""	""	""	""	""	""	""	"brentuximab vedotin"	"Adcetris&reg;|anti-CD30 ADC SGN-35|SGN 35"	""	""	""	"yes"	""	""
"10459"	"brepocitinib"	""	"Synthetic organic"	""	""	""	""	"385612219"	"118878093"	""	""	""	""	""	""	""	"[(1S)-2,2-difluorocyclopropyl]-[(1S,5R)-3-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]methanone"	"brepocitinib"	"compound 23 [PMID: 30113844]|PF-06700841|PF06700841"	"O=C([C@@H]1CC1(F)F)N1[C@@H]2CC[C@H]1CN(C2)c1ccnc(n1)Nc1cnn(c1)C"	"BUWBRTXGQRBBHG-MJBXVCDLSA-N"	"InChI=1S/C18H21F2N7O/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24)/t12-,13+,14-/m0/s1"	"yes"	""	""
"9213"	"briakinumab"	""	"Antibody"	""	""	""	""	"315661289"	""	""	""	""	""	""	""	""	""	"briakinumab"	"ABT-874|J-695|J695|Ozespa"	""	""	""	"yes"	""	""
"9101"	"brimapitide"	""	"Peptide"	""	""	""	""	"315661186"	""	""	""	""	""	""	""	""	""	"brimapitide"	"AM-111|D-JNKI-1|XG-102"	""	""	""	"yes"	""	""
"520"	"brimonidine (UK14304)"	""	"Synthetic organic"	"yes"	""	""	""	"135650022"	"2435"	""	""	"CHEMBL844"	""	""	""	""	"5-bromo-N-(4,5-dihydro-1H-imidazol-2-yl)quinoxalin-6-amine"	"brimonidine"	"Alphagan&reg;|Lumify&reg;|Mirvaso&reg;|UK14,304|UK14304"	"Brc1c(ccc2c1nccn2)NC1=NCCN1"	"XYLJNLCSTIOKRM-UHFFFAOYSA-N"	"InChI=1S/C11H10BrN5/c12-9-7(17-11-15-5-6-16-11)1-2-8-10(9)14-4-3-13-8/h1-4H,5-6H2,(H2,15,16,17)"	"yes"	""	""
"13450"	"briquilimab"	""	"Antibody"	""	""	""	""	"500839860"	""	""	""	""	""	""	""	""	""	"briquilimab"	"AMG-191|AMG191|JSP-191|JSP191"	""	""	""	"yes"	""	""
"10"	"BRL-15572"	""	"Synthetic organic"	""	""	""	""	"135650023"	"3654103"	""	""	"CHEMBL534232"	""	""	""	""	"3-[4-(3-chlorophenyl)piperazin-1-yl]-1,1-di(phenyl)propan-2-ol"	""	"BRL 15572|BRL-15,572|BRL15572"	"Clc1cccc(c1)N1CCN(CC1)CC(C(c1ccccc1)c1ccccc1)O"	"QJHCTHPYUOXOGM-UHFFFAOYSA-N"	"InChI=1S/C25H27ClN2O/c26-22-12-7-13-23(18-22)28-16-14-27(15-17-28)19-24(29)25(20-8-3-1-4-9-20)21-10-5-2-6-11-21/h1-13,18,24-25,29H,14-17,19H2"	"yes"	""	""
"7540"	"brodalumab"	""	"Antibody"	"yes"	""	""	""	"187051841"	""	""	""	""	""	""	""	""	""	"brodalumab"	"AMG-827|AMG827|Kyntheum&reg;|Lumicef&reg;|Siliq&reg;"	""	""	""	"yes"	""	""
"7131"	"bromfenac"	""	"Synthetic organic"	"yes"	""	""	""	"178103707"	"60726"	""	""	"CHEMBL1077"	""	""	""	""	"2-[2-amino-3-(4-bromobenzoyl)phenyl]acetic acid"	"bromfenac"	"AHR-10282B|Bromday&reg;|Prolensa&reg;|Xibrom&reg;"	"OC(=O)Cc1cccc(c1N)C(=O)c1ccc(cc1)Br"	"ZBPLOVFIXSTCRZ-UHFFFAOYSA-N"	"InChI=1S/C15H12BrNO3/c16-11-6-4-9(5-7-11)15(20)12-3-1-2-10(14(12)17)8-13(18)19/h1-7H,8,17H2,(H,18,19)"	"yes"	""	""
"9833"	"BsAb (CD89-CD20)"	""	"Antibody"	""	""	""	""	"363894127"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"12060"	"BT7480"	""	"Peptide"	""	""	""	""	"472319182"	""	""	""	""	""	""	""	""	""	""	"BCY11863|BT-7480"	"O=C(N[C@H]1CSCCC(=O)N2CN3CN(C2)C(=O)CCSC[C@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C1=O)CCC2)Cc1c2c(cccc2)ccc1)CC(=O)O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@H](O)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CC(C1)O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CSCCC3=O)C(=O)N)CCOCCOCCOCCN(CCOCCOCCOCCn1cc(nn1)CCC(=O)NCCCC[C@@H]1C(=O)N2[C@H](C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H]3C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N4[C@@H](CCC4)C(=O)N[C@@H](Cc4ccc(O)cc4)C(=O)N[C@@H](CCCC)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N)CSCCC(=O)N4CN(CN(C(=O)CCSC[C@@H](C(=O)N[C@H](C(=O)N5[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CCC5)CC(C)(C)C)NC(=O)C)C4)C(=O)CCSC3)CCC2)CCOCCOCCOCCn1cc(nn1)CCC(=O)NCCCC[C@@H]1C(=O)N2[C@H](C(=O)N[C@@H](Cc3ccc(O)cc3)C(=O)N[C@@H]3C(=O)N[C@@H](Cc4ccccc4)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)O)C(=O)N4[C@@H](CCC4)C(=O)N[C@@H](Cc4ccc(O)cc4)C(=O)N[C@@H](CCCC)C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N)CSCCC(=O)N4CN(CN(C(=O)CCSC[C@@H](C(=O)N[C@H](C(=O)N5[C@H](C(=O)N[C@H](C(=O)N1)CCC(=O)O)CCC5)CC(C)(C)C)NC(=O)C)C4)C(=O)CCSC3)CCC2"	"DQYZLSMANMRIEI-BOFVMFDGSA-N"	""	"yes"	""	""
"2438"	"BTP2"	""	"Synthetic organic"	""	""	""	""	"135650028"	"2455"	""	""	"CHEMBL262766"	""	""	""	""	"N-[4-[3,5-bis(trifluoromethyl)pyrazol-1-yl]phenyl]-4-methylthiadiazole-5-carboxamide"	""	"YM-58483"	"O=C(c1snnc1C)Nc1ccc(cc1)n1nc(cc1C(F)(F)F)C(F)(F)F"	"XPRZIORDEVHURQ-UHFFFAOYSA-N"	"InChI=1S/C15H9F6N5OS/c1-7-12(28-25-23-7)13(27)22-8-2-4-9(5-3-8)26-11(15(19,20)21)6-10(24-26)14(16,17)18/h2-6H,1H3,(H,22,27)"	"yes"	""	""
"7434"	"budesonide"	""	"Synthetic organic"	"yes"	""	""	""	"178104006"	"5281004"	""	""	"CHEMBL1370"	""	""	""	""	""	"budesonide"	"Entocort&reg;|Eohilia&reg; (budesonide oral suspension)|Jorveza&reg;|Pulmicort&reg;|S-1320|Uceris&reg;"	"CCCC1O[C@H]2[C@](O1)(C(=O)CO)[C@@]1([C@@H](C2)[C@@H]2CCC3=CC(=O)C=C[C@@]3([C@H]2[C@H](C1)O)C)C"	"VOVIALXJUBGFJZ-KWVAZRHASA-N"	"InChI=1S/C25H34O6/c1-4-5-21-30-20-11-17-16-7-6-14-10-15(27)8-9-23(14,2)22(16)18(28)12-24(17,3)25(20,31-21)19(29)13-26/h8-10,16-18,20-22,26,28H,4-7,11-13H2,1-3H3/t16-,17-,18-,20+,21?,22+,23-,24-,25+/m0/s1"	"yes"	""	""
"1059"	"butyric acid"	""	"Metabolite"	""	""	""	""	"135650039"	"264"	""	""	"CHEMBL14227"	""	""	""	""	"butanoic acid"	""	"butanoic acid|butyrate|C4"	"CCCC(=O)O"	"FERIUCNNQQJTOY-UHFFFAOYSA-N"	"InChI=1S/C4H8O2/c1-2-3-4(5)6/h2-3H2,1H3,(H,5,6)"	"yes"	""	""
"767"	"BX 471"	""	"Synthetic organic"	""	""	""	""	"135650045"	"512282"	""	""	"CHEMBL232656"	""	""	""	""	"[5-chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methylpiperazin-1-yl]-2-oxoethoxy]phenyl]urea"	""	"BX-471|BX-741"	"NC(=O)Nc1cc(Cl)ccc1OCC(=O)N1CCN(C[C@H]1C)Cc1ccc(cc1)F"	"XQYASZNUFDVMFH-CQSZACIVSA-N"	"InChI=1S/C21H24ClFN4O3/c1-14-11-26(12-15-2-5-17(23)6-3-15)8-9-27(14)20(28)13-30-19-7-4-16(22)10-18(19)25-21(24)29/h2-7,10,14H,8-9,11-13H2,1H3,(H3,24,25,29)/t14-/m1/s1"	"yes"	""	""
"8006"	"BX-795"	""	"Synthetic organic"	""	""	""	""	"249565686"	"10077147"	""	""	"CHEMBL577784"	""	""	""	""	"N-[3-[[5-iodo-4-[3-(thiophene-2-carbonylamino)propylamino]pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide"	""	"BX 795|BX795"	"O=C(N1CCCC1)Nc1cccc(c1)Nc1ncc(c(n1)NCCCNC(=O)c1cccs1)I"	"VAVXGGRQQJZYBL-UHFFFAOYSA-N"	"InChI=1S/C23H26IN7O2S/c24-18-15-27-22(30-20(18)25-9-5-10-26-21(32)19-8-4-13-34-19)28-16-6-3-7-17(14-16)29-23(33)31-11-1-2-12-31/h3-4,6-8,13-15H,1-2,5,9-12H2,(H,26,32)(H,29,33)(H2,25,27,28,30)"	"yes"	""	""
"9180"	"C108297"	""	"Synthetic organic"	""	""	""	""	"315661262"	"25110774"	""	""	"CHEMBL270575"	""	""	""	""	"(4aR)-6-(4-tert-butylphenyl)sulfonyl-1-(4-fluorophenyl)-4a-(2-methoxyethoxymethyl)-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinoline"	""	"Compound 52  [PMID:18226897]"	"COCCOC[C@@]12Cc3cnn(c3C=C2CCN(C1)S(=O)(=O)c1ccc(cc1)C(C)(C)C)c1ccc(cc1)F"	"OMKDFVUMRKROMY-SSEXGKCCSA-N"	"InChI=1S/C30H36FN3O4S/c1-29(2,3)23-5-11-27(12-6-23)39(35,36)33-14-13-24-17-28-22(18-30(24,20-33)21-38-16-15-37-4)19-32-34(28)26-9-7-25(31)8-10-26/h5-12,17,19H,13-16,18,20-21H2,1-4H3/t30-/m1/s1"	"yes"	""	""
"10719"	"C1-27"	""	"Synthetic organic"	""	""	""	""	"405067313"	"3860347"	""	""	"CHEMBL4210652"	""	""	""	""	"2-chloro-N-[4-chloro-3-(dimethylsulfamoyl)phenyl]acetamide"	""	"GSTO1-IN-1"	"ClCC(=O)Nc1ccc(c(c1)S(=O)(=O)N(C)C)Cl"	"YEHYODCKTNLFQU-UHFFFAOYSA-N"	"InChI=1S/C10H12Cl2N2O3S/c1-14(2)18(16,17)9-5-7(3-4-8(9)12)13-10(15)6-11/h3-5H,6H2,1-2H3,(H,13,15)"	"yes"	""	""
"13136"	"C-176"	""	"Synthetic organic"	""	""	""	""	"491299918"	"1103958"	""	""	"CHEMBL3593839"	""	""	""	""	"N-(4-iodophenyl)-5-nitrofuran-2-carboxamide"	""	"C-176 STING inhibitor"	"C1=CC(=CC=C1NC(=O)C2=CC=C(O2)[N+](=O)[O-])I"	"JBIKQXOZLBLMKI-UHFFFAOYSA-N"	"InChI=1S/C11H7IN2O4/c12-7-1-3-8(4-2-7)13-11(15)9-5-6-10(18-9)14(16)17/h1-6H,(H,13,15)"	"yes"	""	""
"9570"	"C391"	""	"Synthetic organic"	""	""	""	""	"336446956"	"126970682"	""	""	""	""	""	""	""	""	""	"compound 5 [PMID: 27994760]"	"NCCCC[C@H](N1CC2N(CC1=O)C(=O)[C@H](CN2C(=O)c1ccco1)NC(=O)CC(C)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)O)Cc1ccc(cc1)O)CC(C)C"	"OHQDORKALTUSJJ-ZHLQKWORSA-N"	"InChI=1S/C38H53N7O10/c1-22(2)16-26(34(49)42-27(38(53)54)18-24-10-12-25(46)13-11-24)41-35(50)29(8-5-6-14-39)43-20-32-44(37(52)30-9-7-15-55-30)19-28(40-31(47)17-23(3)4)36(51)45(32)21-33(43)48/h7,9-13,15,22-23,26-29,32,46H,5-6,8,14,16-21,39H2,1-4H3,(H,40,47)(H,41,50)(H,42,49)(H,53,54)/t26-,27-,28-,29-,32?/m0/s1"	"yes"	""	""
"573"	"C5a"	"Human"	"Peptide"	""	""	""	""	"135651643"	""	"P01031"	"ENSG00000106804"	""	""	""	""	""	""	""	"C5a anaphylatoxin|complement component C5a|human complement protein"	""	""	""	"yes"	""	""
"7004"	"C646"	""	"Synthetic organic"	""	""	""	""	"178103583"	"1285941"	""	""	"CHEMBL1797936"	""	""	""	""	"4-[(4Z)-4-{[5-(4,5-dimethyl-2-nitrophenyl)furan-2-yl]methylidene}-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl]benzoic acid"	""	""	"CC1=NN(C(=O)/C/1=C\c1ccc(o1)c1cc(C)c(cc1[N+](=O)[O-])C)c1ccc(cc1)C(=O)O"	"HEKJYZZSCQBJGB-UNOMPAQXSA-N"	"InChI=1S/C24H19N3O6/c1-13-10-20(21(27(31)32)11-14(13)2)22-9-8-18(33-22)12-19-15(3)25-26(23(19)28)17-6-4-16(5-7-17)24(29)30/h4-12H,1-3H3,(H,29,30)/b19-12-"	"yes"	""	""
"9107"	"cabiralizumab"	""	"Antibody"	""	""	""	""	"315661192"	""	""	""	""	""	""	""	""	""	"cabiralizumab"	"BMS-986227|FPA-008|FPA008"	""	""	""	"yes"	""	""
"12966"	"cadonilimab"	""	"Antibody"	"yes"	""	""	""	"485206087"	""	""	""	""	""	""	""	""	""	"cadonilimab"	"AK-104|AK104"	""	""	""	"yes"	""	""
"13506"	"cambritaxestat"	""	"Synthetic organic"	""	""	""	""	"500839916"	"122199235"	""	""	"CHEMBL3917975"	""	""	""	""	"N-[(1S)-1-(4-chlorophenyl)ethyl]-3-[3-[[4-(trifluoromethoxy)phenyl]methyl]imidazo[4,5-b]pyridin-2-yl]propanamide"	"cambritaxestat"	"compound 9v [PMID: 27780639]|CRT-0273750|CRT0273750|IOA-289"	"C[C@@H](C1=CC=C(C=C1)Cl)NC(=O)CCC2=NC3=C(N2CC4=CC=C(C=C4)OC(F)(F)F)N=CC=C3"	"HXYXHSDYBDFOFO-INIZCTEOSA-N"	"InChI=1S/C25H22ClF3N4O2/c1-16(18-6-8-19(26)9-7-18)31-23(34)13-12-22-32-21-3-2-14-30-24(21)33(22)15-17-4-10-20(11-5-17)35-25(27,28)29/h2-11,14,16H,12-13,15H2,1H3,(H,31,34)/t16-/m0/s1"	"yes"	""	""
"13187"	"camoteskimab"	""	"Antibody"	""	""	""	""	"491299969"	""	""	""	""	""	""	""	""	""	"camoteskimab"	"AEVI 007|AEVI-007|AVTX 007|AVTX-007|CERC 007|CERC-007|MEDI 2338"	""	""	""	"yes"	""	""
"9758"	"camrelizumab"	""	"Antibody"	"yes"	""	""	""	"354702231"	""	""	""	""	""	""	""	""	""	"camrelizumab"	"INCSHR1210|SHR-1210"	""	""	""	"yes"	""	""
"6773"	"canakinumab"	""	"Antibody"	"yes"	""	""	""	"178103379"	""	""	""	""	""	""	""	""	""	"canakinumab"	"ACZ 885|ACZ885|Ilaris&reg;"	""	""	""	"yes"	""	""
"5675"	"canertinib"	""	"Synthetic organic"	""	""	""	""	"178102302"	"156414"	""	""	"CHEMBL31965"	""	""	""	""	"N-{4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(morpholin-4-yl)propoxy]quinazolin-6-yl}prop-2-enamide"	"canertinib"	"CI 1033|CI-1033|PD 183805 dihydrochloride"	"C=CC(=O)Nc1cc2c(ncnc2cc1OCCCN1CCOCC1)Nc1ccc(c(c1)Cl)F"	"OMZCMEYTWSXEPZ-UHFFFAOYSA-N"	"InChI=1S/C24H25ClFN5O3/c1-2-23(32)30-21-13-17-20(14-22(21)34-9-3-6-31-7-10-33-11-8-31)27-15-28-24(17)29-16-4-5-19(26)18(25)12-16/h2,4-5,12-15H,1,3,6-11H2,(H,30,32)(H,27,28,29)"	"yes"	""	""
"10511"	"carotegrast"	""	"Synthetic organic"	""	""	""	""	"387065593"	"10120218"	""	""	""	""	""	""	""	"(2S)-2-[(2,6-dichlorobenzoyl)amino]-3-[4-[6-(dimethylamino)-1-methyl-2,4-dioxoquinazolin-3-yl]phenyl]propanoic acid"	"carotegrast"	"HCA2969"	"CN(c1ccc2c(c1)c(=O)n(c(=O)n2C)c1ccc(cc1)C[C@@H](C(=O)O)NC(=O)c1c(Cl)cccc1Cl)C"	"YQKBOUPIOWUMTE-NRFANRHFSA-N"	"InChI=1S/C27H24Cl2N4O5/c1-31(2)17-11-12-22-18(14-17)25(35)33(27(38)32(22)3)16-9-7-15(8-10-16)13-21(26(36)37)30-24(34)23-19(28)5-4-6-20(23)29/h4-12,14,21H,13H2,1-3H3,(H,30,34)(H,36,37)/t21-/m0/s1"	"yes"	""	""
"10510"	"carotegrast methyl"	""	"Synthetic organic"	"yes"	""	""	""	"387065592"	"9872780"	""	""	""	""	""	""	""	""	"carotegrast"	"AJM-300|AJM300|Carogra&reg;"	"COC(=O)[C@@H](NC(=O)c1c(Cl)cccc1Cl)Cc1ccc(cc1)n1c(=O)c2cc(ccc2n(c1=O)C)N(C)C"	"MMHHPKCJJIFLBQ-QFIPXVFZSA-N"	"InChI=1S/C28H26Cl2N4O5/c1-32(2)18-12-13-23-19(15-18)26(36)34(28(38)33(23)3)17-10-8-16(9-11-17)14-22(27(37)39-4)31-25(35)24-20(29)6-5-7-21(24)30/h5-13,15,22H,14H2,1-4H3,(H,31,35)/t22-/m0/s1"	"yes"	""	""
"7141"	"carprofen"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178103717"	"2581"	""	""	"CHEMBL1316"	""	""	""	""	"2-(6-chloro-9H-carbazol-2-yl)propanoic acid"	"carprofen"	"Ro-205720000"	"OC(=O)C(c1ccc2c(c1)[nH]c1c2cc(cc1)Cl)C"	"PUXBGTOOZJQSKH-UHFFFAOYSA-N"	"InChI=1S/C15H12ClNO2/c1-8(15(18)19)9-2-4-11-12-7-10(16)3-5-13(12)17-14(11)6-9/h2-8,17H,1H3,(H,18,19)"	"yes"	""	""
"14306"	"CB-13"	""	"Synthetic organic"	""	""	""	""	"523352098"	"9799417"	""	""	"CHEMBL244403"	""	""	""	""	"naphthalen-1-yl-(4-pentoxynaphthalen-1-yl)methanone"	""	"CB13|CRA-13|CRA13|NVP-SAB378"	"CCCCCOC1=CC=C(C2=CC=CC=C21)C(=O)C3=CC=CC4=CC=CC=C43"	"RSUMDJRTAFBISX-UHFFFAOYSA-N"	"InChI=1S/C26H24O2/c1-2-3-8-18-28-25-17-16-24(21-13-6-7-14-22(21)25)26(27)23-15-9-11-19-10-4-5-12-20(19)23/h4-7,9-17H,2-3,8,18H2,1H3"	"yes"	""	""
"9610"	"CBS-3595"	""	"Synthetic organic"	""	""	""	""	"340590240"	"10450926"	""	""	"CHEMBL432798"	""	""	""	""	"N-[4-[5-(4-fluorophenyl)-3-methyl-2-methylsulfanylimidazol-4-yl]pyridin-2-yl]acetamide"	""	""	"CSc1nc(c(n1C)c1ccnc(c1)NC(=O)C)c1ccc(cc1)F"	"CJKGORBZVWDVRY-UHFFFAOYSA-N"	"InChI=1S/C18H17FN4OS/c1-11(24)21-15-10-13(8-9-20-15)17-16(22-18(25-3)23(17)2)12-4-6-14(19)7-5-12/h4-10H,1-3H3,(H,20,21,24)"	"yes"	""	""
"9224"	"CC-885"	""	"Synthetic organic"	""	""	""	""	"340590211"	"24788636"	""	""	""	""	""	""	""	"3-(3-chloro-4-methylphenyl)-1-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea"	""	""	"O=C(Nc1ccc(c(c1)Cl)C)NCc1ccc2c(c1)CN(C2=O)C1CCC(=O)NC1=O"	"DOEVCIHTTTYVCC-UHFFFAOYSA-N"	"InChI=1S/C22H21ClN4O4/c1-12-2-4-15(9-17(12)23)25-22(31)24-10-13-3-5-16-14(8-13)11-27(21(16)30)18-6-7-19(28)26-20(18)29/h2-5,8-9,18H,6-7,10-11H2,1H3,(H2,24,25,31)(H,26,28,29)"	"yes"	""	""
"4404"	"CCL1"	"Mouse"	"Peptide"	""	""	""	""	"135651652"	""	"P10146"	"ENSMUSG00000020702"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"812"	"CCL1"	"Human"	"Peptide"	""	""	""	""	"135651653"	""	"P22362"	"ENSG00000108702"	""	""	""	""	""	""	""	"I309|TCA-3"	""	""	""	"yes"	""	""
"787"	"CCL11"	"Mouse"	"Peptide"	""	""	""	""	"135651656"	""	"P48298"	"ENSMUSG00000020676"	""	""	""	""	""	""	""	"murine eotaxin"	""	""	""	"yes"	""	""
"769"	"CCL11"	"Human"	"Peptide"	""	""	""	""	"135651654"	""	"P51671"	"ENSG00000172156"	""	""	""	""	""	""	""	"eotaxin"	""	""	""	"yes"	""	""
"4416"	"CCL11"	"Rat"	"Peptide"	""	""	""	""	"135651655"	""	"P97545"	"ENSRNOG00000007335"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4435"	"CCL12"	"Mouse"	"Peptide"	""	""	""	""	"178101199"	""	"Q62401"	"ENSMUSG00000035352"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"770"	"CCL13"	"Human"	"Peptide"	""	""	""	""	"135651657"	""	"Q99616"	"ENSG00000181374"	""	""	""	""	""	""	""	"monocyte chemotactic protein-4"	""	""	""	"yes"	""	""
"753"	"CCL14"	"Human"	"Peptide"	""	""	""	""	"135651658"	""	"Q16627"	"ENSG00000276409"	""	""	""	""	""	""	""	"CCL14a|CK&beta;1|haemofiltrate CC chemokine 1 (HCC-1)|HCC-1(1-74)"	""	""	""	"yes"	""	""
"754"	"CCL15"	"Human"	"Peptide"	""	""	""	""	"135651659"	""	"Q16663"	"ENSG00000275718"	""	""	""	""	""	""	""	"Lkn-1 [Leukotactin-1]|macrophage inflammatory protein-1&delta;|MIP-1&delta;"	""	""	""	"yes"	""	""
"1272"	"CCL16"	"Human"	"Peptide"	""	""	""	""	"135651660"	""	"O15467"	"ENSG00000275152"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"797"	"CCL17"	"Human"	"Peptide"	""	""	""	""	"135651661"	""	"Q92583"	"ENSG00000102970"	""	""	""	""	""	""	""	"TARC|thymus- and activation-regulated chemokine"	""	""	""	"yes"	""	""
"4382"	"CCL18"	"Human"	"Peptide"	""	""	""	""	"178101190"	""	"P55774"	"ENSG00000275385"	""	""	""	""	""	""	""	"macrophage inflammatory protein 4|small-inducible cytokine A18"	""	""	""	"yes"	""	""
"4417"	"CCL19"	"Mouse"	"Peptide"	""	""	""	""	"135651662"	""	"O70460"	"ENSMUSG00000071005"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"810"	"CCL19"	"Human"	"Peptide"	""	""	""	""	"135651663"	""	"Q99731"	"ENSG00000172724"	""	""	""	""	""	""	""	"&beta;-chemokine exodus-3|ck &beta;-11|ck&beta;11|MIP-3&beta;"	""	""	""	"yes"	""	""
"771"	"CCL2"	"Human"	"Peptide"	""	""	""	""	"135651664"	""	"P13500"	"ENSG00000108691"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4407"	"CCL2"	"Rat"	"Peptide"	""	""	""	""	"135651666"	""	"P14844"	"ENSRNOG00000007159"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4406"	"CCL2"	"Mouse"	"Peptide"	""	""	""	""	"135651665"	""	"P10148"	"ENSMUSG00000035385"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4418"	"CCL20"	"Mouse"	"Peptide"	""	""	""	""	"135651669"	""	"O89093"	"ENSMUSG00000026166"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"808"	"CCL20"	"Human"	"Peptide"	""	""	""	""	"135651668"	""	"P78556"	"ENSG00000115009"	""	""	""	""	""	""	""	"LARC|liver and activation-regulated chemokine|macrophage inflammatory protein-3&alpha;|MIP-3&alpha;"	""	""	""	"yes"	""	""
"4419"	"CCL20"	"Rat"	"Peptide"	""	""	""	""	"135651667"	""	"P97884"	"ENSRNOG00000015992"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"811"	"CCL21"	"Human"	"Peptide"	""	""	""	""	"135651670"	""	"O00585"	"ENSG00000137077"	""	""	""	""	""	""	""	"ck&beta;9|TCA-4"	""	""	""	"yes"	""	""
"8651"	"Ccl21a"	"Mouse"	"Peptide"	""	""	""	""	"252166851"	""	"P84444"	"ENSMUSG00000094686"	""	""	""	""	""	""	""	"6Ckine-Ser|Exodus-2"	""	""	""	"yes"	""	""
"8652"	"Ccl21b"	"Mouse"	"Peptide"	""	""	""	""	"252166852"	""	"P86792"	"ENSMUSG00000095675"	""	""	""	""	""	""	""	"6Ckine-Leu|Exodus-2"	""	""	""	"yes"	""	""
"4420"	"CCL22"	"Mouse"	"Peptide"	""	""	""	""	"135651671"	""	"O88430"	"ENSMUSG00000031779"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"798"	"CCL22"	"Human"	"Peptide"	""	""	""	""	"135651672"	""	"O00626"	"ENSG00000102962"	""	""	""	""	""	""	""	"dc/&beta;-ck|macrophage-derived chemokine|STCP1"	""	""	""	"yes"	""	""
"755"	"CCL23"	"Human"	"Peptide"	""	""	""	""	"135651673"	""	"P55773"	"ENSG00000274736"	""	""	""	""	""	""	""	"ck&beta;8-1|myeloid progenitor inhibitor factor-1"	""	""	""	"yes"	""	""
"775"	"CCL24"	"Human"	"Peptide"	""	""	""	""	"135651675"	""	"O00175"	"ENSG00000106178"	""	""	""	""	""	""	""	"eotaxin-2"	""	""	""	"yes"	""	""
"4421"	"CCL24"	"Mouse"	"Peptide"	""	""	""	""	"135651674"	""	"Q9JKC0"	"ENSMUSG00000004814"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4422"	"CCL25"	"Mouse"	"Peptide"	""	""	""	""	"135651676"	""	"O35903"	"ENSMUSG00000023235"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"817"	"CCL25"	"Human"	"Peptide"	""	""	""	""	"135651677"	""	"O15444"	"ENSG00000131142"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"776"	"CCL26"	"Human"	"Peptide"	""	""	""	""	"135651678"	""	"Q9Y258"	"ENSG00000006606"	""	""	""	""	""	""	""	"MIP-4&alpha;|PTEC"	""	""	""	"yes"	""	""
"3646"	"CCL27"	"Human"	"Peptide"	""	""	""	""	"135651679"	""	"Q9Y4X3"	"ENSG00000213927"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4462"	"CCL27"	"Mouse"	"Peptide"	""	""	""	""	"135651680"	""	"Q9Z1X0"	"ENSMUSG00000073888"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4463"	"CCL28"	"Mouse"	"Peptide"	""	""	""	""	"135651682"	""	"Q9JIL2"	"ENSMUSG00000074715"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"3649"	"CCL28"	"Human"	"Peptide"	""	""	""	""	"135651681"	""	"Q9NRJ3"	"ENSG00000151882"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4409"	"CCL3"	"Rat"	"Peptide"	""	""	""	""	"135651683"	""	""	"ENSRNOG00000011205"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"756"	"CCL3"	"Human"	"Peptide"	""	""	""	""	"135651684"	""	"P10147"	"ENSG00000277632"	""	""	""	""	""	""	""	"macrophage inflammatory protein-1&alpha;|MIP-1&alpha;"	""	""	""	"yes"	""	""
"4408"	"CCL3"	"Mouse"	"Peptide"	""	""	""	""	"135651685"	""	"P10855"	"ENSMUSG00000000982"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4410"	"CCL4"	"Mouse"	"Peptide"	""	""	""	""	"135651686"	""	"P14097"	"ENSMUSG00000018930"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"757"	"CCL4"	"Human"	"Peptide"	""	""	""	""	"135651687"	""	"P13236"	"ENSG00000275302"	""	""	""	""	""	""	""	"HC21|macrophage inflammatory protein-1&beta;|MIP-1&beta;"	""	""	""	"yes"	""	""
"4411"	"CCL4"	"Rat"	"Peptide"	""	""	""	""	"135651688"	""	"P50230"	"ENSRNOG00000011406"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"758"	"CCL5"	"Human"	"Peptide"	""	""	""	""	"135651690"	""	"P13501"	"ENSG00000271503"	""	""	""	""	""	""	""	"eosinophil chemotactic cytokine [EoCP]|regulated upon activation normal T cell expressed and secreted (RANTES)"	""	""	""	"yes"	""	""
"4412"	"CCL5"	"Mouse, Rat"	"Peptide"	""	""	""	""	"135651689"	""	"P30882|P50231"	"ENSMUSG00000035042"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4413"	"CCL7"	"Mouse"	"Peptide"	""	""	""	""	"135651691"	""	"Q03366"	"ENSMUSG00000035373"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"759"	"CCL7"	"Human"	"Peptide"	""	""	""	""	"135651693"	""	"P80098"	"ENSG00000108688"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4414"	"CCL7"	"Rat"	"Peptide"	""	""	""	""	"135651692"	""	"Q9QXY8"	"ENSRNOG00000000239"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4415"	"CCL8"	"Mouse"	"Peptide"	""	""	""	""	"135651695"	""	"Q9Z12"	"ENSMUSG00000009185"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"772"	"CCL8"	"Human"	"Peptide"	""	""	""	""	"135651694"	""	"P80075"	"ENSG00000108700"	""	""	""	""	""	""	""	"monocyte chemotactic protein-2"	""	""	""	"yes"	""	""
"4434"	"CCL9"	"Mouse"	"Peptide"	""	""	""	""	"178101198"	""	"P51670"	"ENSMUSG00000019122"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9431"	"CCR2-RA-[R]"	""	"Synthetic organic"	""	""	""	""	"328083531"	"12093170"	""	""	""	""	""	""	""	"(2R)-3-acetyl-1-(4-chloro-2-fluorophenyl)-2-cyclohexyl-4-hydroxy-2H-pyrrol-5-one"	""	"analog 49 (Dasse <i>et al</i>., 2007)"	"Clc1ccc(c(c1)F)N1[C@H](C2CCCCC2)C(=C(C1=O)O)C(=O)C"	"VQNLJXWZGVRLBA-MRXNPFEDSA-N"	"InChI=1S/C18H19ClFNO3/c1-10(22)15-16(11-5-3-2-4-6-11)21(18(24)17(15)23)14-8-7-12(19)9-13(14)20/h7-9,11,16,23H,2-6H2,1H3/t16-/m1/s1"	"yes"	""	""
"10164"	"CCX354"	""	"Synthetic organic"	""	""	""	""	"381118874"	"135565361"	""	""	""	""	""	""	""	"1-[4-(4-chloro-3-methoxyphenyl)piperazin-1-yl]-2-(3-imidazol-2-ylidene-2H-pyrazolo[3,4-b]pyridin-1-yl)ethanone"	""	"CCX 354|CCX-354|CCX-354-C"	"COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1[nH]c(=C2N=CC=N2)c2c1nccc2"	"WSVDLXWYJRCDBZ-UHFFFAOYSA-N"	"InChI=1S/C22H22ClN7O2/c1-32-18-13-15(4-5-17(18)23)28-9-11-29(12-10-28)19(31)14-30-22-16(3-2-6-26-22)20(27-30)21-24-7-8-25-21/h2-8,13,27H,9-12,14H2,1H3"	"yes"	""	""
"5077"	"CD40 ligand"	"Human"	"Peptide"	""	""	""	""	"178101770"	""	"P29965"	"ENSG00000102245"	""	""	""	""	""	""	""	"CD40 ligand, membrane form"	""	""	""	"yes"	""	""
"9330"	"CDP840"	""	"Synthetic organic"	""	""	""	""	"318164849"	"127928"	""	""	"CHEMBL32442"	""	""	""	""	"4-[(2R)-2-(3-cyclopentyloxy-4-methoxyphenyl)-2-phenylethyl]pyridine"	""	"CDP 840|CDP-840"	"COc1ccc(cc1OC1CCCC1)[C@@H](c1ccccc1)Cc1ccncc1"	"UTUUPXBCDMQYRR-HSZRJFAPSA-N"	"InChI=1S/C25H27NO2/c1-27-24-12-11-21(18-25(24)28-22-9-5-6-10-22)23(20-7-3-2-4-8-20)17-19-13-15-26-16-14-19/h2-4,7-8,11-16,18,22-23H,5-6,9-10,17H2,1H3/t23-/m1/s1"	"yes"	""	""
"12350"	"CEE321"	""	"Synthetic organic"	""	""	""	""	"479821141"	"129165016"	""	""	""	""	""	""	""	"4-(2-chloroanilino)-6-[(6-methylpyridin-2-yl)amino]pyridine-3-carboxamide"	""	"CEE-321|compound 1e [PMID: 36657024]"	"O=C(N)c1c(Nc2ccccc2Cl)cc(Nc2nc(C)ccc2)nc1"	"OYWNKAAPXTYEBN-UHFFFAOYSA-N"	"InChI=1S/C18H16ClN5O/c1-11-5-4-8-16(22-11)24-17-9-15(12(10-21-17)18(20)25)23-14-7-3-2-6-13(14)19/h2-10H,1H3,(H2,20,25)(H2,21,22,23,24)"	"yes"	""	""
"10386"	"celastrol"	""	"Natural product"	""	""	""	""	"384403665"	"122724"	""	""	""	""	""	""	""	"(2R,4aS,6aR,6aS,14aS,14bR)-10-hydroxy-2,4a,6a,6a,9,14a-hexamethyl-11-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid"	""	"compound 2 [PMID: 28621943]"	"O=C1C=C2C(=CC=C3[C@@]2(C)CC[C@@]2([C@]3(C)CC[C@@]3([C@H]2C[C@@](C)(CC3)C(=O)O)C)C)C(=C1O)C"	"KQJSQWZMSAGSHN-JJWQIEBTSA-N"	"InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,31H,9-14,16H2,1-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1"	"yes"	""	""
"2892"	"celecoxib"	""	"Synthetic organic"	"yes"	""	""	""	"178100241"	"2662"	""	""	"CHEMBL118"	""	""	""	""	"4-[5-(4-methylphenyl)-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide"	"celecoxib"	"Celecox&reg;|Elyxyb&reg; (DFN-15; oral solution)|Onsenal&reg;|SC-58635|SC58635"	"Cc1ccc(cc1)c1cc(nn1c1ccc(cc1)S(=O)(=O)N)C(F)(F)F"	"RZEKVGVHFLEQIL-UHFFFAOYSA-N"	"InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)"	"yes"	""	""
"10090"	"cemiplimab"	""	"Antibody"	"yes"	""	""	""	"381118800"	""	""	""	""	""	""	""	""	""	"cemiplimab"	"cemiplimab-rwlc|Libtayo&reg;|REGN-2810|REGN2810|SAR-439684|SAR439684"	""	""	""	"yes"	""	""
"9824"	"cenerimod"	""	"Synthetic organic"	""	""	""	""	"354702295"	"49871973"	""	""	""	""	""	""	""	"(2S)-3-[4-[5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]propane-1,2-diol"	""	"ACT-334441"	"OC[C@@H](COc1c(C)cc(cc1CC)c1noc(n1)c1cc(OC)nc(c1)C1CCCC1)O"	"KJKKMMMRWISKRF-FQEVSTJZSA-N"	"InChI=1S/C25H31N3O5/c1-4-16-10-18(9-15(2)23(16)32-14-20(30)13-29)24-27-25(33-28-24)19-11-21(17-7-5-6-8-17)26-22(12-19)31-3/h9-12,17,20,29-30H,4-8,13-14H2,1-3H3/t20-/m0/s1"	"yes"	""	""
"801"	"cenicriviroc"	""	"Synthetic organic"	""	""	""	""	"135651229"	"11285792"	""	""	"CHEMBL2110727"	""	""	""	""	"(5E)-8-[4-(2-butoxyethoxy)phenyl]-1-(2-methylpropyl)-N-[4-[(S)-(3-propylimidazol-4-yl)methylsulfinyl]phenyl]-3,4-dihydro-2H-1-benzazocine-5-carboxamide"	"cenicriviroc"	"TAK 652|TAK-652|TAK652|TBR-652"	"CCCCOCCOc1ccc(cc1)c1ccc2c(c1)C=C(CCCN2CC(C)C)C(=O)Nc1ccc(cc1)[S@@](=O)Cc1cncn1CCC"	"PNDKCRDVVKJPKG-WHERJAGFSA-N"	"InChI=1S/C41H52N4O4S/c1-5-7-22-48-23-24-49-38-15-10-32(11-16-38)33-12-19-40-35(25-33)26-34(9-8-21-44(40)28-31(3)4)41(46)43-36-13-17-39(18-14-36)50(47)29-37-27-42-30-45(37)20-6-2/h10-19,25-27,30-31H,5-9,20-24,28-29H2,1-4H3,(H,43,46)/b34-26+/t50-/m0/s1"	"yes"	""	""
"8957"	"cerdulatinib"	""	"Synthetic organic"	""	""	""	""	"310264738"	"44595079"	""	""	""	""	""	""	""	"4-(cyclopropylamino)-2-[4-(4-ethylsulfonylpiperazin-1-yl)anilino]pyrimidine-5-carboxamide"	"cerdulatinib"	"PRT 062070|PRT-062070|PRT-2070|PRT062070"	"CCS(=O)(=O)N1CCN(CC1)c1ccc(cc1)Nc1ncc(c(n1)NC1CC1)C(=O)N"	"BGLPECHZZQDNCD-UHFFFAOYSA-N"	"InChI=1S/C20H27N7O3S/c1-2-31(29,30)27-11-9-26(10-12-27)16-7-5-15(6-8-16)24-20-22-13-17(18(21)28)19(25-20)23-14-3-4-14/h5-8,13-14H,2-4,9-12H2,1H3,(H2,21,28)(H2,22,23,24,25)"	"yes"	""	""
"6774"	"certolizumab pegol"	""	"Antibody"	"yes"	""	""	""	"178103380"	""	""	""	""	""	""	""	""	""	"certolizumab pegol"	"CDP870|Cimzia&reg;|PHA 738144"	""	""	""	"yes"	""	""
"1222"	"cetirizine"	""	"Synthetic organic"	"yes"	""	""	""	"135650064"	"2678"	""	""	"CHEMBL1000"	""	""	""	""	"2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid"	"cetirizine"	"Reactine&reg;|Zyrtec&reg;"	"OC(=O)COCCN1CCN(CC1)C(c1ccc(cc1)Cl)c1ccccc1"	"ZKLPARSLTMPFCP-UHFFFAOYSA-N"	"InChI=1S/C21H25ClN2O3/c22-19-8-6-18(7-9-19)21(17-4-2-1-3-5-17)24-12-10-23(11-13-24)14-15-27-16-20(25)26/h1-9,21H,10-16H2,(H,25,26)"	"yes"	""	""
"1190"	"cetrorelix"	""	"Peptide"	"yes"	""	""	""	"135652055"	"25074887"	""	""	"CHEMBL1200490"	""	""	""	""	""	"cetrorelix"	"Cetrotide&reg;|SB-075"	"OC[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(=O)N)C)CCCN=C(N)N)CC(C)C)CCCNC(=O)N)Cc1ccc(cc1)O)NC(=O)[C@@H](Cc1cccnc1)NC(=O)[C@@H](Cc1ccc(cc1)Cl)NC(=O)[C@@H](Cc1ccc2c(c1)cccc2)NC(=O)C"	"SBNPWPIBESPSIF-MHWMIDJBSA-N"	"InChI=1S/C70H92ClN17O14/c1-39(2)31-52(61(94)82-51(15-9-28-77-69(73)74)68(101)88-30-10-16-58(88)67(100)79-40(3)59(72)92)83-60(93)50(14-8-29-78-70(75)102)81-63(96)54(34-43-20-25-49(91)26-21-43)86-66(99)57(38-89)87-65(98)56(36-45-11-7-27-76-37-45)85-64(97)55(33-42-18-23-48(71)24-19-42)84-62(95)53(80-41(4)90)35-44-17-22-46-12-5-6-13-47(46)32-44/h5-7,11-13,17-27,32,37,39-40,50-58,89,91H,8-10,14-16,28-31,33-36,38H2,1-4H3,(H2,72,92)(H,79,100)(H,80,90)(H,81,96)(H,82,94)(H,83,93)(H,84,95)(H,85,97)(H,86,99)(H,87,98)(H4,73,74,77)(H3,75,78,102)/t40-,50-,51+,52+,53-,54+,55-,56-,57+,58+/m1/s1"	"yes"	""	""
"10055"	"CG200745"	""	"Synthetic organic"	""	""	""	""	"375973243"	"16117309"	""	""	""	""	""	""	""	"(E)-N-(3-dimethylaminopropyl)-N'-hydroxy-2-(naphthalen-1-yloxymethyl)oct-2-enediamide"	""	"CG-2|CG-200745|HDCG-0745"	"ONC(=O)CCCC/C=C(/C(=O)NCCCN(C)C)\COc1cccc2c1cccc2"	"AUGCSOFQTDKPSO-RGVLZGJSSA-N"	"InChI=1S/C24H33N3O4/c1-27(2)17-9-16-25-24(29)20(11-4-3-5-15-23(28)26-30)18-31-22-14-8-12-19-10-6-7-13-21(19)22/h6-8,10-14,30H,3-5,9,15-18H2,1-2H3,(H,25,29)(H,26,28)/b20-11+"	"yes"	""	""
"8066"	"CGI1746"	""	"Synthetic organic"	""	""	""	""	"249565746"	"24857323"	""	""	"CHEMBL1230541"	""	""	""	""	"4-tert-butyl-N-[2-methyl-3-[4-methyl-6-[4-(morpholine-4-carbonyl)anilino]-5-oxopyrazin-2-yl]phenyl]benzamide"	""	"CGI 1746|CGI-1746"	"Cc1c(cccc1c1cn(C)c(=O)c(n1)Nc1ccc(cc1)C(=O)N1CCOCC1)NC(=O)c1ccc(cc1)C(C)(C)C"	"JIFCFQDXHMUPGP-UHFFFAOYSA-N"	"InChI=1S/C34H37N5O4/c1-22-27(7-6-8-28(22)37-31(40)23-9-13-25(14-10-23)34(2,3)4)29-21-38(5)33(42)30(36-29)35-26-15-11-24(12-16-26)32(41)39-17-19-43-20-18-39/h6-16,21H,17-20H2,1-5H3,(H,35,36)(H,37,40)"	"yes"	""	""
"9264"	"CGI560"	""	"Synthetic organic"	""	""	""	""	"315661339"	"11397050"	""	""	"CHEMBL2057914"	""	""	""	""	""	""	"CGI-560"	"O=C(c1ccc(cc1)C(C)(C)C)Nc1cccc(c1)c1nc(Nc2ccccc2)c2n(c1)ccn2"	"IJMHHZDBRUGXNO-UHFFFAOYSA-N"	"InChI=1S/C29H27N5O/c1-29(2,3)22-14-12-20(13-15-22)28(35)32-24-11-7-8-21(18-24)25-19-34-17-16-30-27(34)26(33-25)31-23-9-5-4-6-10-23/h4-19H,1-3H3,(H,31,33)(H,32,35)"	"yes"	""	""
"9844"	"CH-4051"	""	"Synthetic organic"	""	""	""	""	"363894138"	"11532464"	""	""	""	""	""	""	""	"(2S)-2-[[4-[2-(2,4-diaminoquinazolin-6-yl)ethyl]benzoyl]amino]-4-methylidenepentanedioic acid"	""	"Formula (10) [WO2012078708A1]"	"OC(=O)[C@@H](NC(=O)c1ccc(cc1)CCc1ccc2c(c1)c(N)nc(n2)N)CC(=C)C(=O)O"	"NAWXUBYGYWOOIX-SFHVURJKSA-N"	"InChI=1S/C23H23N5O5/c1-12(21(30)31)10-18(22(32)33)26-20(29)15-7-4-13(5-8-15)2-3-14-6-9-17-16(11-14)19(24)28-23(25)27-17/h4-9,11,18H,1-3,10H2,(H,26,29)(H,30,31)(H,32,33)(H4,24,25,27,28)/t18-/m0/s1"	"yes"	""	""
"5535"	"chloroquine"	""	"Synthetic organic"	"yes"	""	""	""	"178102177"	"2719"	""	""	"CHEMBL76"	""	""	""	""	"N'-(7-chloroquinolin-4-yl)-N,N-diethylpentane-1,4-diamine"	"chloroquine"	"Aralen&reg;|chloraquine|Malaquin&reg;"	"CCN(CCCC(Nc1ccnc2c1ccc(c2)Cl)C)CC"	"WHTVZRBIWZFKQO-UHFFFAOYSA-N"	"InChI=1S/C18H26ClN3/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21)"	"yes"	"yes"	""
"9516"	"CHMFL-BTK-11"	""	"Synthetic organic"	""	""	""	""	"336446903"	"126970680"	""	""	""	""	""	""	""	"N-{2-methyl-5-[2-oxo-9-(1H-pyrazol-1-yl)-1H,2H,3H,4H-benzo[h]1,6-naphthyridin-1-yl]phenyl}prop-2-enamide"	""	""	"C=CC(=O)Nc1cc(ccc1C)N1C(=O)CCc2c1c1cc(ccc1nc2)n1cccn1"	"AANOKQLITQDWQD-UHFFFAOYSA-N"	"InChI=1S/C25H21N5O2/c1-3-23(31)28-22-14-19(7-5-16(22)2)30-24(32)10-6-17-15-26-21-9-8-18(13-20(21)25(17)30)29-12-4-11-27-29/h3-5,7-9,11-15H,1,6,10H2,2H3,(H,28,31)"	"yes"	""	""
"9677"	"cibinetide"	""	"Peptide"	""	""	""	""	"348353636"	"91810664"	""	""	"CHEMBL3545305"	""	""	""	""	"(4S)-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(1S)-1-carboxy-2-hydroxyethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-oxo-4-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoic acid"	"cibinetide"	"ARA 290|ARA-290|PH-BSP|PHBSP"	"OC[C@@H](C(=O)N[C@H](C(=O)O)CO)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCC(=O)N1)CCC(=O)O)CCC(=O)N)CC(C)C)CCC(=O)O)CCCN=C(N)N)C)CC(C)C)CC(=O)N"	"WZTIQQBMSJTRBR-WYKNNRPVSA-N"	"InChI=1S/C51H84N16O21/c1-22(2)17-30(47(84)65-32(19-36(53)71)48(85)66-33(20-68)49(86)67-34(21-69)50(87)88)63-40(77)24(5)57-41(78)25(7-6-16-56-51(54)55)59-43(80)29(11-15-39(75)76)62-46(83)31(18-23(3)4)64-45(82)27(8-12-35(52)70)60-44(81)28(10-14-38(73)74)61-42(79)26-9-13-37(72)58-26/h22-34,68-69H,6-21H2,1-5H3,(H2,52,70)(H2,53,71)(H,57,78)(H,58,72)(H,59,80)(H,60,81)(H,61,79)(H,62,83)(H,63,77)(H,64,82)(H,65,84)(H,66,85)(H,67,86)(H,73,74)(H,75,76)(H,87,88)(H4,54,55,56)/t24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-/m0/s1"	"yes"	""	""
"1917"	"cicaprost"	""	"Synthetic organic"	""	""	""	""	"135650094"	"5311044"	""	""	"CHEMBL160629"	""	""	""	""	"2-{2-[(2E,3aS,4S,5R,6aS)-5-hydroxy-4-[(3S,4S)-3-hydroxy-4-methylnona-1,6-diyn-1-yl]-octahydropentalen-2-ylidene]ethoxy}acetic acid"	"cicaprost"	"ZK 96480|ZK-96480"	"CCC#CC[C@@H]([C@@H](C#C[C@H]1[C@H](O)C[C@H]2[C@@H]1C/C(=C/COCC(=O)O)/C2)O)C"	"ARUGKOZUKWAXDS-SEWALLKFSA-N"	"InChI=1S/C22H30O5/c1-3-4-5-6-15(2)20(23)8-7-18-19-12-16(9-10-27-14-22(25)26)11-17(19)13-21(18)24/h9,15,17-21,23-24H,3,6,10-14H2,1-2H3,(H,25,26)/b16-9+/t15-,17-,18+,19-,20+,21+/m0/s1"	"yes"	""	""
"7469"	"ciclesonide"	""	"Synthetic organic"	"yes"	""	""	""	"187051772"	"6918155"	""	""	"CHEMBL2040682"	""	""	""	""	""	"ciclesonide"	"Alvesco&reg;|Omnaris&reg;|RPR-251526"	"O=C(C(C)C)OCC(=O)[C@@]12O[C@@H](O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1CCC1=CC(=O)C=C[C@]21C)C1CCCCC1"	"LUKZNWIVRBCLON-GXOBDPJESA-N"	"InChI=1S/C32H44O7/c1-18(2)28(36)37-17-25(35)32-26(38-29(39-32)19-8-6-5-7-9-19)15-23-22-11-10-20-14-21(33)12-13-30(20,3)27(22)24(34)16-31(23,32)4/h12-14,18-19,22-24,26-27,29,34H,5-11,15-17H2,1-4H3/t22-,23-,24-,26+,27+,29+,30-,31-,32+/m0/s1"	"yes"	""	""
"10190"	"ciforadenant"	""	"Synthetic organic"	""	""	""	""	"381118900"	"44537963"	""	""	""	""	""	""	""	"7-(5-methylfuran-2-yl)-3-[[6-[[(3S)-oxolan-3-yl]oxymethyl]pyridin-2-yl]methyl]triazolo[4,5-d]pyrimidin-5-amine"	"ciforadenant"	"CPI-444|CPI444|V-81444|V81444"	"Nc1nc(c2ccc(o2)C)c2c(n1)n(nn2)Cc1cccc(n1)CO[C@@H]1COCC1"	"KURQKNMKCGYWRJ-HNNXBMFYSA-N"	"InChI=1S/C20H21N7O3/c1-12-5-6-16(30-12)17-18-19(24-20(21)23-17)27(26-25-18)9-13-3-2-4-14(22-13)10-29-15-7-8-28-11-15/h2-6,15H,7-11H2,1H3,(H2,21,23,24)/t15-/m0/s1"	"yes"	""	""
"7407"	"cilomilast"	""	"Synthetic organic"	""	""	""	""	"178103979"	"151170"	""	""	"CHEMBL511115"	""	""	""	""	"(1s,4s)-4-cyano-4-[3-(cyclopentyloxy)-4-methoxyphenyl]cyclohexane-1-carboxylic acid"	"cilomilast"	"SB-207499"	"N#C[C@@]1(CC[C@@H](CC1)C(=O)O)c1ccc(c(c1)OC1CCCC1)OC"	"CFBUZOUXXHZCFB-OYOVHJISSA-N"	"InChI=1S/C20H25NO4/c1-24-17-7-6-15(12-18(17)25-16-4-2-3-5-16)20(13-21)10-8-14(9-11-20)19(22)23/h6-7,12,14,16H,2-5,8-11H2,1H3,(H,22,23)/t14-,20-"	"yes"	""	""
"10045"	"cintirorgon"	""	"Synthetic organic"	""	""	""	""	"375973233"	"124126348"	""	""	""	""	""	""	""	"3-[(2S)-6-[3-(difluoromethoxy)-5-fluorophenyl]-4-[3-(trifluoromethyl)phenyl]sulfonyl-2,3-dihydro-1,4-benzoxazin-2-yl]-2,2-dimethylpropanoic acid"	"cintirorgon"	"compound 32J [WO2016201225A1]|LYC-55716|LYC55716"	"FC(Oc1cc(F)cc(c1)c1ccc2c(c1)N(C[C@@H](O2)CC(C(=O)O)(C)C)S(=O)(=O)c1cccc(c1)C(F)(F)F)F"	"GULSIMHVQYBADX-FQEVSTJZSA-N"	"InChI=1S/C27H23F6NO6S/c1-26(2,24(35)36)13-20-14-34(41(37,38)21-5-3-4-17(11-21)27(31,32)33)22-10-15(6-7-23(22)39-20)16-8-18(28)12-19(9-16)40-25(29)30/h3-12,20,25H,13-14H2,1-2H3,(H,35,36)/t20-/m0/s1"	"yes"	""	""
"6466"	"cipemastat"	""	"Synthetic organic"	""	""	""	""	"178103080"	"9824350"	""	""	"CHEMBL115653"	""	""	""	""	"(2R,3R)-3-(cyclopentylmethyl)-N-hydroxy-4-oxo-4-piperidin-1-yl-2-[(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl)methyl]butanamide"	"cipemastat"	"Ro 28-2653"	"ONC(=O)[C@H]([C@H](C(=O)N1CCCCC1)CC1CCCC1)CN1C(=O)N(C(C1=O)(C)C)C"	"GFUITADOEPNRML-SJORKVTESA-N"	"InChI=1S/C22H36N4O5/c1-22(2)20(29)26(21(30)24(22)3)14-17(18(27)23-31)16(13-15-9-5-6-10-15)19(28)25-11-7-4-8-12-25/h15-17,31H,4-14H2,1-3H3,(H,23,27)/t16-,17+/m1/s1"	"yes"	""	""
"14472"	"ciprocopan"	""	"Synthetic organic"	""	""	""	""	""	"176080762"	""	""	""	""	""	""	""	"4-[(2S,4R)-4-cyclopropyl-1-[[7-methyl-5-(trideuteriomethoxy)-1H-indol-4-yl]methyl]piperidin-2-yl]benzoic acid"	"ciprocopan"	"Compound A [WO2025119266]|HSK-39297|HSK39297"	"[2H]C([2H])([2H])OC1=C(C2=C(C(=C1)C)NC=C2)CN3CC[C@H](C[C@H]3C4=CC=C(C=C4)C(=O)O)C5CC5"	"VHBASIXWLLDPFC-HRFXIYCZSA-N"	"InChI=1S/C26H30N2O3/c1-16-13-24(31-2)22(21-9-11-27-25(16)21)15-28-12-10-20(17-3-4-17)14-23(28)18-5-7-19(8-6-18)26(29)30/h5-9,11,13,17,20,23,27H,3-4,10,12,14-15H2,1-2H3,(H,29,30)/t20-,23+/m1/s1/i2D3"	"yes"	""	""
"12868"	"civorebrutinib"	""	"Synthetic organic"	""	""	""	""	"485205989"	"132162130"	""	""	""	""	""	""	""	"5-amino-3-[4-(5-chloropyridin-2-yl)oxyphenyl]-1-[(6R)-4-cyano-4-azaspiro[2.5]octan-6-yl]pyrazole-4-carboxamide"	""	""	"NC1=C(C(=NN1[C@H]2CN(C3(CC3)CC2)C#N)C4=CC=C(C=C4)OC5=NC=C(C=C5)Cl)C(=O)N"	"OSEITUBGGJDFBK-MRXNPFEDSA-N"	"InChI=1S/C23H22ClN7O2/c24-15-3-6-18(28-11-15)33-17-4-1-14(2-5-17)20-19(22(27)32)21(26)31(29-20)16-7-8-23(9-10-23)30(12-16)13-25/h1-6,11,16H,7-10,12,26H2,(H2,27,32)/t16-/m1/s1"	"yes"	""	""
"14514"	"cizutamig"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"cizutamig"	"CD3med FIT-Ig|EMB-06|EMB06"	""	""	""	"yes"	""	""
"9195"	"clazakizumab"	""	"Antibody"	""	""	""	""	"315661274"	""	""	""	""	""	""	""	""	""	"clazakizumab"	"ALD-518|ALD518|BMS-945429"	""	""	""	"yes"	""	""
"6063"	"clemastine"	""	"Synthetic organic"	"yes"	""	""	""	"178102684"	"26987"	""	""	"CHEMBL1626"	""	""	""	""	"(2R)-2-[2-[(1R)-1-(4-chlorophenyl)-1-phenylethoxy]ethyl]-1-methylpyrrolidine"	"clemastine"	"HS-592|meclastin|Tavegil&reg;|Tavist&reg;"	"Clc1ccc(cc1)[C@@](c1ccccc1)(OCC[C@H]1CCCN1C)C"	"YNNUSGIPVFPVBX-NHCUHLMSSA-N"	"InChI=1S/C21H26ClNO/c1-21(17-7-4-3-5-8-17,18-10-12-19(22)13-11-18)24-16-14-20-9-6-15-23(20)2/h3-5,7-8,10-13,20H,6,9,14-16H2,1-2H3/t20-,21-/m1/s1"	"yes"	""	""
"10285"	"clemizole"	""	"Synthetic organic"	""	""	""	""	"381744966"	"2782"	""	""	"CHEMBL1407943"	""	""	""	""	"1-[(4-chlorophenyl)methyl]-2-(pyrrolidin-1-ylmethyl)benzimidazole"	""	""	"Clc1ccc(cc1)Cn1c(CN2CCCC2)nc2c1cccc2"	"CJXAEXPPLWQRFR-UHFFFAOYSA-N"	"InChI=1S/C19H20ClN3/c20-16-9-7-15(8-10-16)13-23-18-6-2-1-5-17(18)21-19(23)14-22-11-3-4-12-22/h1-2,5-10H,3-4,11-14H2"	"yes"	""	""
"1223"	"clobenpropit"	""	"Synthetic organic"	""	""	""	""	"135650109"	"2790"	""	""	"CHEMBL14690"	""	""	""	""	"N'-[(4-chlorophenyl)methyl]-1-[3-(3H-imidazol-4-yl)propylsulfanyl]methanimidamide"	""	"VUF 9153|VUF-9153"	"Clc1ccc(cc1)CN=C(SCCCc1cnc[nH]1)N"	"UCAIEVHKDLMIFL-UHFFFAOYSA-N"	"InChI=1S/C14H17ClN4S/c15-12-5-3-11(4-6-12)8-18-14(16)20-7-1-2-13-9-17-10-19-13/h3-6,9-10H,1-2,7-8H2,(H2,16,18)(H,17,19)"	"yes"	""	""
"7062"	"clobetasol propionate"	""	"Synthetic organic"	"yes"	""	""	""	"178103641"	"32798"	""	""	"CHEMBL1159650"	""	""	""	""	"[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate"	"clobetasol"	"CCI-4725|Clobex&reg;|Dermovate&reg;|GR 2/925|Temovate&reg;"	"CCC(=O)O[C@@]1([C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F)C(=O)CCl"	"CBGUOGMQLZIXBE-XGQKBEPLSA-N"	"InChI=1S/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1"	"yes"	""	""
"9088"	"clobetasone"	""	"Synthetic organic"	"yes"	""	""	""	"315661173"	"71387"	""	""	""	""	""	""	""	"(8S,9R,10S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-17-hydroxy-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthrene-3,11-dione"	"clobetasone"	"Eumovate&reg;"	"ClCC(=O)[C@@]1(O)[C@@H](C)C[C@@H]2[C@]1(C)CC(=O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F"	"XXIFVOHLGBURIG-OZCCCYNHSA-N"	"InChI=1S/C22H26ClFO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-16,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,19-,20-,21-,22-/m0/s1"	"yes"	""	""
"9605"	"clodronic acid"	""	"Synthetic organic"	"yes"	""	""	""	"340590235"	"25419"	""	""	"CHEMBL12318"	""	""	""	""	"(dichloro-phosphonomethyl)phosphonic acid"	"clodronic acid"	"Bonefos&reg;|Clasteon &reg;|clodronate|Loron&reg;"	"ClC(P(=O)(O)O)(P(=O)(O)O)Cl"	"ACSIXWWBWUQEHA-UHFFFAOYSA-N"	"InChI=1S/CH4Cl2O6P2/c2-1(3,10(4,5)6)11(7,8)9/h(H2,4,5,6)(H2,7,8,9)"	"yes"	""	""
"9184"	"clofazimine"	""	"Synthetic organic"	"yes"	""	""	""	"315661264"	"2794"	""	""	"CHEMBL1292"	""	""	""	""	"N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine"	"clofazimine"	"Lamprene&reg;"	"Clc1ccc(cc1)Nc1cc2nc3ccccc3n(c2cc1=NC(C)C)c1ccc(cc1)Cl"	"WDQPAMHFFCXSNU-UHFFFAOYSA-N"	"InChI=1S/C27H22Cl2N4/c1-17(2)30-24-16-27-25(15-23(24)31-20-11-7-18(28)8-12-20)32-22-5-3-4-6-26(22)33(27)21-13-9-19(29)10-14-21/h3-17,31H,1-2H3"	"yes"	""	"yes"
"1772"	"clopidogrel (active metabolite)"	""	"Synthetic organic"	""	""	""	""	"135649894"	"10066813"	""	""	""	""	""	""	""	"(2Z)-2-[1-[(1S)-1-(2-chlorophenyl)-2-methoxy-2-oxoethyl]-4-sulfanylpiperidin-3-ylidene]acetic acid"	""	""	"COC(=O)[C@H](c1ccccc1Cl)N1CCC(/C(=C\C(=O)O)/C1)S"	"CWUDNVCEAAXNQA-AWGNNQSZSA-N"	"InChI=1S/C16H18ClNO4S/c1-22-16(21)15(11-4-2-3-5-12(11)17)18-7-6-13(23)10(9-18)8-14(19)20/h2-5,8,13,15,23H,6-7,9H2,1H3,(H,19,20)/b10-8-/t13?,15-/m0/s1"	"yes"	""	""
"9266"	"CNX-774"	""	"Synthetic organic"	""	""	""	""	"315661341"	"59174579"	""	""	"CHEMBL2216827"	""	""	""	""	"4-[4-[[5-fluoro-4-[3-(prop-2-enoylamino)anilino]pyrimidin-2-yl]amino]phenoxy]-N-methylpyridine-2-carboxamide"	""	""	"C=CC(=O)Nc1cccc(c1)Nc1nc(ncc1F)Nc1ccc(cc1)Oc1ccnc(c1)C(=O)NC"	"VVLHQJDAUIPZFH-UHFFFAOYSA-N"	"InChI=1S/C26H22FN7O3/c1-3-23(35)31-17-5-4-6-18(13-17)32-24-21(27)15-30-26(34-24)33-16-7-9-19(10-8-16)37-20-11-12-29-22(14-20)25(36)28-2/h3-15H,1H2,2H3,(H,28,36)(H,31,35)(H2,30,32,33,34)"	"yes"	""	""
"2367"	"colchicine"	""	"Synthetic organic"	"yes"	""	""	""	"135650118"	"6167"	""	""	"CHEMBL107"	""	""	""	""	"N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]acetamide"	""	"Colcrys&reg;|methoxylated analogue of XD1|XD25"	"COc1c(OC)cc2c(c1OC)c1ccc(c(=O)cc1[C@H](CC2)NC(=O)C)OC"	"IAKHMKGGTNLKSZ-INIZCTEOSA-N"	"InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1"	"yes"	""	""
"9414"	"complement C3"	"Human"	"Peptide"	""	""	""	""	"328083516"	""	"P01024"	"ENSG00000125730"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"8712"	"complement C5"	"Human"	"Peptide"	""	""	""	""	"252827370"	""	"P01031"	"ENSG00000106804"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"10435"	"compound 10a [PMID: 31283223]"	""	"Synthetic organic"	""	""	""	""	"385612195"	"139030521"	""	""	""	""	""	""	""	"2-butylpyrazolo[1,5-a]quinoxalin-4-amine"	""	""	"CCCCc1nn2c(c1)c(N)nc1c2cccc1"	"YMNPLUINBRDMEW-UHFFFAOYSA-N"	"InChI=1S/C14H16N4/c1-2-3-6-10-9-13-14(15)16-11-7-4-5-8-12(11)18(13)17-10/h4-5,7-9H,2-3,6H2,1H3,(H2,15,16)"	"yes"	""	""
"10488"	"compound 10 [PMID: 31411465]"	""	"Synthetic organic"	""	""	""	""	"385612247"	"139030534"	""	""	""	""	""	""	""	"1-(3-((cis)-3-(2-Butylpyrrolidine-1-carbonyl)cyclohexyl)phenyl)-5-cyclopropyl-1H-pyrazole-4-carboxylic acid"	""	"example 8 (cis racemate) [WO2017060855A1]"	"CCCCC1CCCN1C(=O)[C@@H]1CCC[C@@H](C1)c1cccc(c1)n1ncc(c1C1CC1)C(=O)O"	"UHBPMQISVQNVGD-PDOMDSBESA-N"	"InChI=1S/C28H37N3O3/c1-2-3-10-23-12-6-15-30(23)27(32)22-9-4-7-20(16-22)21-8-5-11-24(17-21)31-26(19-13-14-19)25(18-29-31)28(33)34/h5,8,11,17-20,22-23H,2-4,6-7,9-10,12-16H2,1H3,(H,33,34)/t20-,22+,23?/m0/s1"	"yes"	""	""
"9819"	"compound 11 [PMID: 29442501]"	""	"Synthetic organic"	""	""	""	""	"354702291"	"132427690"	""	""	""	""	""	""	""	"(3S)-3-[(2S)-2-[(2S)-2-{5-[(3aS,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanamido}-3-methylbutanamido]-3-(4-hydroxyphenyl)propanamido]-3-({1-[bis(4-chlorophenoxy)phosphoryl]butyl}carbamoyl)propanoic acid"	""	""	"CCCC(P(=O)(Oc1ccc(cc1)Cl)Oc1ccc(cc1)Cl)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)CCCCC1SC[C@H]2[C@@H]1NC(=O)N2)Cc1ccc(cc1)O)CC(=O)O"	"QFLWZFQWSBQYPS-AWRAUJHKSA-N"	"InChI=1S/C44H55Cl2N6O11PS/c1-4-7-37(64(61,62-30-18-12-27(45)13-19-30)63-31-20-14-28(46)15-21-31)51-42(58)33(23-38(55)56)47-41(57)32(22-26-10-16-29(53)17-11-26)48-43(59)39(25(2)3)50-36(54)9-6-5-8-35-40-34(24-65-35)49-44(60)52-40/h10-21,25,32-35,37,39-40,53H,4-9,22-24H2,1-3H3,(H,47,57)(H,48,59)(H,50,54)(H,51,58)(H,55,56)(H2,49,52,60)/t32-,33-,34-,35?,37?,39-,40-/m0/s1"	"yes"	""	""
"9684"	"compound 12a [PMID: 29031075]"	""	"Synthetic organic"	""	""	""	""	"348353643"	"131801158"	""	""	""	""	""	""	""	"9-(4-chlorobenzoyl)-6-methanesulfonyl-2,3,4,9-tetrahydro-1H-carbazol-4-one"	""	""	"Clc1ccc(cc1)C(=O)n1c2ccc(cc2c2c1CCCC2=O)S(=O)(=O)C"	"MITGKKFYIJJQGL-UHFFFAOYSA-N"	"InChI=1S/C20H16ClNO4S/c1-27(25,26)14-9-10-16-15(11-14)19-17(3-2-4-18(19)23)22(16)20(24)12-5-7-13(21)8-6-12/h5-11H,2-4H2,1H3"	"yes"	""	""
"9690"	"compound 12p [Larson <i>et al.</i>, 2017]"	""	"Synthetic organic"	""	""	""	""	"348353649"	"130276131"	""	""	""	""	""	""	""	"methyl 4-amino-1-(2-aminoethyl)-2-butylimidazo[4,5-c]quinoline-7-carboxylate"	""	""	"NCCn1c(CCCC)nc2c1c1ccc(cc1nc2N)C(=O)OC"	"ZYCFMHCDZSVIGF-UHFFFAOYSA-N"	"InChI=1S/C18H23N5O2/c1-3-4-5-14-22-15-16(23(14)9-8-19)12-7-6-11(18(24)25-2)10-13(12)21-17(15)20/h6-7,10H,3-5,8-9,19H2,1-2H3,(H2,20,21)"	"yes"	""	""
"9453"	"compound 12 [PMID: 27448772]"	""	"Synthetic organic"	""	""	""	""	"329968393"	"135567181"	""	""	""	""	""	""	""	"N-[3-(4-methylpiperazine-1-carbonyl)-2-propan-2-yloxyphenyl]-4-oxo-1H-thieno[3,2-d]pyrimidine-7-carboxamide"	""	""	"CN1CCN(CC1)C(=O)c1cccc(c1OC(C)C)NC(=O)c1csc2c1nc[nH]c2=O"	"MJJJFOLDERHCND-UHFFFAOYSA-N"	"InChI=1S/C22H25N5O4S/c1-13(2)31-18-14(22(30)27-9-7-26(3)8-10-27)5-4-6-16(18)25-20(28)15-11-32-19-17(15)23-12-24-21(19)29/h4-6,11-13H,7-10H2,1-3H3,(H,25,28)(H,23,24,29)"	"yes"	""	""
"11936"	"compound 14f [PMID: 35063894]"	""	"Synthetic organic"	""	""	""	""	"461663491"	"162679547"	""	""	""	""	""	""	""	"N-(cyclopropanesulfonyl)-5-cyclopropyl-2-[(cyclopropylmethyl)[(1R)-1-[5'-methyl-2'-(5-oxo-2,5-dihydro-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl]ethyl]amino]-1,3-thiazole-4-carboxamide"	""	""	"C[C@@H](N(CC1CC1)c1nc(C(=O)NS(=O)(=O)C2CC2)c(s1)C1CC1)c1ccc(cc1)c1cc(C)ccc1c1nc(=O)o[nH]1"	"FQGLCYYIHLNVRG-GOSISDBHSA-N"	"InChI=1S/C31H33N5O5S2/c1-17-3-14-24(28-33-31(38)41-34-28)25(15-17)21-8-6-20(7-9-21)18(2)36(16-19-4-5-19)30-32-26(27(42-30)22-10-11-22)29(37)35-43(39,40)23-12-13-23/h3,6-9,14-15,18-19,22-23H,4-5,10-13,16H2,1-2H3,(H,35,37)(H,33,34,38)/t18-/m1/s1"	"yes"	""	""
"12351"	"compound 14 [Schnute <i>et al</i>., 2023]"	""	"Synthetic organic"	""	""	""	""	"479821142"	"167993636"	""	""	""	""	""	""	""	""	""	""	"CC(C)C(=O)N1CCN2C[C@@H]1CCCCCS(=O)(=O)Nc1cccc(C2)c1C"	"GMUUZFVHYAPQEI-IBGZPJMESA-N"	"InChI=1S/C21H33N3O3S/c1-16(2)21(25)24-12-11-23-14-18-8-7-10-20(17(18)3)22-28(26,27)13-6-4-5-9-19(24)15-23/h7-8,10,16,19,22H,4-6,9,11-15H2,1-3H3/t19-/m0/s1"	"yes"	""	""
"9078"	"compound 15 [PMID: 25411721]"	""	"Synthetic organic"	""	""	""	""	"315661163"	"60166172"	""	""	""	""	""	""	""	"N-(4-fluoro-2-methylphenyl)-3-methyl-N-[(2-methyl-1H-indol-4-yl)methyl]pyridine-4-carboxamide"	""	"example 252 [WO2007110237]"	"Fc1ccc(c(c1)C)N(C(=O)c1ccncc1C)Cc1cccc2c1cc([nH]2)C"	"FMASTMURQSHELY-UHFFFAOYSA-N"	"InChI=1S/C24H22FN3O/c1-15-11-19(25)7-8-23(15)28(24(29)20-9-10-26-13-16(20)2)14-18-5-4-6-22-21(18)12-17(3)27-22/h4-13,27H,14H2,1-3H3"	"yes"	""	""
"10706"	"compound 15 [PMID: 32045236]"	""	"Synthetic organic"	""	""	""	""	"404859153"	"145996542"	""	""	""	""	""	""	""	"2-Iodoadenosine-5′-O-[(phosphonomethyl)phosphonic Acid]"	""	""	"O[C@@H]1[C@@H](COP(=O)(CP(=O)(O)O)O)O[C@H]([C@@H]1O)n1cnc2c1nc(I)nc2N"	"OJRUSAPKCPIVBY-KQYNXXCUSA-N"	"InChI=1S/C11H16IN5O9P2/c12-11-15-8(13)5-9(16-11)17(2-14-5)10-7(19)6(18)4(26-10)1-25-28(23,24)3-27(20,21)22/h2,4,6-7,10,18-19H,1,3H2,(H,23,24)(H2,13,15,16)(H2,20,21,22)/t4-,6-,7-,10-/m1/s1"	"yes"	""	""
"13044"	"compound 15z [PMID: 38029358]"	""	"Synthetic organic"	""	""	""	""	"491299826"	"169494481"	""	""	""	""	""	""	""	"N-(5-Chloro-2-(2-methoxyethoxy)benzyl)-N-(5-(N-propylsulfamoyl)-2,3-dihydro-1H-inden-2-yl)benzofuran-2-carboxamide"	""	"NLRP3 inhibitor 15z"	"O=S(C1=CC2=C(CC(N(C(C3=CC4=C(C=CC=C4)O3)=O)CC5=C(OCCOC)C=CC(Cl)=C5)C2)C=C1)(NCCC)=O"	"NDHJABNMYOMGPH-UHFFFAOYSA-N"	"InChI=1S/C31H33ClN2O6S/c1-3-12-33-41(36,37)27-10-8-21-16-26(17-23(21)18-27)34(31(35)30-19-22-6-4-5-7-29(22)40-30)20-24-15-25(32)9-11-28(24)39-14-13-38-2/h4-11,15,18-19,26,33H,3,12-14,16-17,20H2,1-2H3"	"yes"	""	""
"10502"	"compound 16i [PMID: 31525963]"	""	"Synthetic organic"	""	""	""	""	"387065584"	"139593558"	""	""	""	""	""	""	""	""	""	""	"O=C([C@@H]1CCC(=O)N1c1cccs1)NCc1ccc(cc1Cl)Cl"	"PCHSDJRKGJKOAG-ZDUSSCGKSA-N"	"InChI=1S/C16H14Cl2N2O2S/c17-11-4-3-10(12(18)8-11)9-19-16(22)13-5-6-14(21)20(13)15-2-1-7-23-15/h1-4,7-8,13H,5-6,9H2,(H,19,22)/t13-/m0/s1"	"yes"	""	""
"9223"	"compound 16 [PMID: 26794040]"	""	"Synthetic organic"	""	""	""	""	"315661299"	"90309142"	""	""	""	""	""	""	""	"2-[4-[3-(4-fluorophenoxy)-5-[[3-hydroxy-3-(2-methylpropyl)pyrrolidine-1-carbonyl]amino]phenoxy]phenyl]-2-methylpropanoic acid"	""	""	"Fc1ccc(cc1)Oc1cc(Oc2ccc(cc2)C(C(=O)O)(C)C)cc(c1)NC(=O)N1CCC(C1)(O)CC(C)C"	"WCDFXVWDGHHCSI-UHFFFAOYSA-N"	"InChI=1S/C31H35FN2O6/c1-20(2)18-31(38)13-14-34(19-31)29(37)33-23-15-26(17-27(16-23)40-25-11-7-22(32)8-12-25)39-24-9-5-21(6-10-24)30(3,4)28(35)36/h5-12,15-17,20,38H,13-14,18-19H2,1-4H3,(H,33,37)(H,35,36)"	"yes"	""	""
"10501"	"compound 16 [PMID: 31525966]"	""	"Synthetic organic"	""	""	""	""	"387065583"	"139269773"	""	""	""	""	""	""	""	""	""	""	"COc1ncc(cc1NS(=O)(=O)c1ccc(cc1F)F)c1ccc(s1)c1cnc2c(c1)CN(C2=O)C"	"ZYYGNLSPUWSHQW-UHFFFAOYSA-N"	"InChI=1S/C24H18F2N4O4S2/c1-30-12-15-7-13(10-27-22(15)24(30)31)19-4-5-20(35-19)14-8-18(23(34-2)28-11-14)29-36(32,33)21-6-3-16(25)9-17(21)26/h3-11,29H,12H2,1-2H3"	"yes"	""	""
"8196"	"compound 17d [PMID: 23099093]"	""	"Synthetic organic"	""	""	""	""	"249565876"	"44465558"	""	""	"CHEMBL2207198"	""	""	""	""	"N-{3-[(5-cyclopropyl-2-{[4-(morpholin-4-yl)phenyl]amino}pyrimidin-4-yl)amino]propyl}cyclobutanecarboxamide"	""	""	"O=C(C1CCC1)NCCCNc1nc(ncc1C1CC1)Nc1ccc(cc1)N1CCOCC1"	"CJPMSUUANYLPET-UHFFFAOYSA-N"	"InChI=1S/C25H34N6O2/c32-24(19-3-1-4-19)27-12-2-11-26-23-22(18-5-6-18)17-28-25(30-23)29-20-7-9-21(10-8-20)31-13-15-33-16-14-31/h7-10,17-19H,1-6,11-16H2,(H,27,32)(H2,26,28,29,30)"	"yes"	""	""
"10035"	"compound 17l [PMID: 26288691]"	""	"Synthetic organic"	""	""	""	""	"375973223"	"122192273"	""	""	"CHEMBL3623107"	""	""	""	""	"2-[2-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]phenyl]isoindole-1,3-dione"	""	""	"COc1ccc(cc1OC)/C=C/c1ccccc1N1C(=O)c2c(C1=O)cccc2"	"MKFOSSOUEAENMG-ACCUITESSA-N"	"InChI=1S/C24H19NO4/c1-28-21-14-12-16(15-22(21)29-2)11-13-17-7-3-6-10-20(17)25-23(26)18-8-4-5-9-19(18)24(25)27/h3-15H,1-2H3/b13-11+"	"yes"	""	""
"10005"	"compound 17 [PMID: 29741897]"	""	"Synthetic organic"	""	""	""	""	"374883892"	"58392644"	""	""	""	""	""	""	""	""	""	""	"OCC(=O)[C@@]12CN(C[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)Cc1cccc(c1)Cl"	"AOSZTAHDEDLTLQ-AZKQZHLXSA-N"	"InChI=1S/C30H34ClF2NO4/c1-27-7-6-20(36)10-23(27)24(32)11-22-21-9-18-14-34(13-17-4-3-5-19(31)8-17)16-29(18,26(38)15-35)28(21,2)12-25(37)30(22,27)33/h3-8,10,18,21-22,24-25,35,37H,9,11-16H2,1-2H3/t18-,21-,22-,24-,25-,27-,28-,29+,30-/m0/s1"	"yes"	""	""
"13005"	"compound 182 [PMID: 37500611]"	""	"Synthetic organic"	""	""	""	""	"485206126"	"155103226"	""	""	""	""	""	""	""	"5-(1-Fluoro-3-hydroxy-7-(3-hydroxy-3-methylbutoxy)naphthalen-2-yl)-1,2,5-thiadiazolidin-3-one 1,1-dioxide"	""	"compound XI [PMID: 37500611]"	"FC1=C(C(=CC2=CC=C(C=C12)OCCC(C)(C)O)O)N3CC(NS3(=O)=O)=O"	"KJYRSQLWJMEJNM-UHFFFAOYSA-N"	"InChI=1S/C17H19FN2O6S/c1-17(2,23)5-6-26-11-4-3-10-7-13(21)16(15(18)12(10)8-11)20-9-14(22)19-27(20,24)25/h3-4,7-8,21,23H,5-6,9H2,1-2H3,(H,19,22)"	"yes"	""	""
"9227"	"compound 18c [PMID: 25901531]"	""	"Synthetic organic"	""	""	""	""	"315661302"	"71660551"	""	""	"CHEMBL3426781"	""	""	""	""	"8-(3,5-dichlorophenyl)sulfanyl-9-[3-(propan-2-ylamino)propyl]purin-6-amine"	""	""	"CC(NCCCn1c(Sc2cc(Cl)cc(c2)Cl)nc2c1ncnc2N)C"	"JYSLFQTWNRYWJT-UHFFFAOYSA-N"	"InChI=1S/C17H20Cl2N6S/c1-10(2)21-4-3-5-25-16-14(15(20)22-9-23-16)24-17(25)26-13-7-11(18)6-12(19)8-13/h6-10,21H,3-5H2,1-2H3,(H2,20,22,23)"	"yes"	""	""
"10549"	"compound 18e [PMID: 31670517]"	""	"Synthetic organic"	""	""	""	""	"404858998"	"139600335"	""	""	""	""	""	""	""	"2-((1-(2-Fluoro-4-((4-(1-isopropyl-1H-pyrazol-4-yl)-5-methylpyrimidin-2-yl)amino)phenyl)piperidin-4-yl)(methyl)amino)ethan-1-ol"	""	""	"OCCN(C1CCN(CC1)c1ccc(cc1F)Nc1ncc(c(n1)c1cnn(c1)C(C)C)C)C"	"CVLXNRIQVFIVGY-UHFFFAOYSA-N"	"InChI=1S/C25H34FN7O/c1-17(2)33-16-19(15-28-33)24-18(3)14-27-25(30-24)29-20-5-6-23(22(26)13-20)32-9-7-21(8-10-32)31(4)11-12-34/h5-6,13-17,21,34H,7-12H2,1-4H3,(H,27,29,30)"	"yes"	""	""
"9842"	"compound 19a [PMID: 26506089]"	""	"Synthetic organic"	""	""	""	""	"363894136"	"86292328"	""	""	"CHEMBL3741938"	""	""	""	""	"[4-[(E)-4-[[(2S)-1-[(2S)-2-[(4-iodophenyl)-phenylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate"	""	""	"Ic1ccc(cc1)N(C(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)(C)C)NC(=O)/C=C(/c1ccc(cc1)OP(=O)(O)O)\C)c1ccccc1"	"CGLGRSOJPUXNFA-YVXBOAIISA-N"	"InChI=1S/C33H37IN3O7P/c1-22(23-12-18-27(19-13-23)44-45(41,42)43)21-29(38)35-30(33(2,3)4)32(40)36-20-8-11-28(36)31(39)37(25-9-6-5-7-10-25)26-16-14-24(34)15-17-26/h5-7,9-10,12-19,21,28,30H,8,11,20H2,1-4H3,(H,35,38)(H2,41,42,43)/b22-21+/t28-,30+/m0/s1"	"yes"	""	""
"9092"	"compound 1 [PMID: 24930776]"	""	"Synthetic organic"	""	""	""	""	"315661177"	"6817797"	""	""	""	""	""	""	""	"6-[(Z)-2-(2,4-diaminophenyl)diazen-1-yl]-3-[(E)-2-{4-[(E)-2-(2,4-diaminophenyl)diazen-1-yl]-3-sulfophenyl}diazen-1-yl]-4-hydroxynaphthalene-2-sulfonic acid"	""	"DB36"	"Nc1ccc(c(c1)N)/N=N\c1ccc2c(c1)c(O)c(c(c2)S(=O)(=O)O)/N=N/c1ccc(c(c1)S(=O)(=O)O)/N=N/c1ccc(cc1N)N"	"ADRMADAIKSWNOR-GOCYIQQKSA-N"	"InChI=1S/C28H24N10O7S2/c29-15-2-6-22(20(31)10-15)35-33-17-4-1-14-9-26(47(43,44)45)27(28(39)19(14)12-17)38-34-18-5-8-24(25(13-18)46(40,41)42)37-36-23-7-3-16(30)11-21(23)32/h1-13,39H,29-32H2,(H,40,41,42)(H,43,44,45)/b35-33-,37-36+,38-34+"	"yes"	""	""
"9673"	"compound 1 [PMID: 28611375]"	""	"Synthetic organic"	""	""	""	""	"348353632"	"2898484"	""	""	""	""	""	""	""	"N-(3-chloro-2-methylphenyl)-N-[2-oxo-2-[4-(phenylmethyl)piperazin-1-yl]ethyl]benzenesulfonamide"	""	""	"O=C(N1CCN(CC1)Cc1ccccc1)CN(S(=O)(=O)c1ccccc1)c1cccc(c1C)Cl"	"QTYHUADZOPIUME-UHFFFAOYSA-N"	"InChI=1S/C26H28ClN3O3S/c1-21-24(27)13-8-14-25(21)30(34(32,33)23-11-6-3-7-12-23)20-26(31)29-17-15-28(16-18-29)19-22-9-4-2-5-10-22/h2-14H,15-20H2,1H3"	"yes"	""	""
"10481"	"compound 1 [PMID: 31477924]"	""	"Synthetic organic"	""	""	""	""	"385612240"	"139030530"	""	""	""	""	""	""	""	""	""	""	"Cc1ccc2c(c1C#Cc1cnc3n1nccc3)onc2Nc1cccc(c1)C(F)(F)F"	"GDBAAUWGHRTFSE-UHFFFAOYSA-N"	"InChI=1S/C23H14F3N5O/c1-14-7-9-19-21(18(14)10-8-17-13-27-20-6-3-11-28-31(17)20)32-30-22(19)29-16-5-2-4-15(12-16)23(24,25)26/h2-7,9,11-13H,1H3,(H,29,30)"	"yes"	""	""
"8084"	"compound 1 [WO2012007375]"	""	"Synthetic organic"	""	""	""	""	"249565764"	"58056241"	""	""	""	""	""	""	""	"N-{2-[4-(aminomethyl)piperidin-1-yl]-5-chlorophenyl}-6-hydroxypyrazolo[1,5-a]pyrimidine-3-carboxamide"	""	""	"NCC1CCN(CC1)c1ccc(cc1NC(=O)c1cnn2c1ncc(c2)O)Cl"	"BNVZRFQNZWYPQH-UHFFFAOYSA-N"	"InChI=1S/C19H21ClN6O2/c20-13-1-2-17(25-5-3-12(8-21)4-6-25)16(7-13)24-19(28)15-10-23-26-11-14(27)9-22-18(15)26/h1-2,7,9-12,27H,3-6,8,21H2,(H,24,28)"	"yes"	""	""
"14501"	"compound 1 [WO2024229295]"	""	"Synthetic organic"	""	""	""	""	""	"168774465"	""	""	""	""	""	""	""	"3-[4-[7-cyano-1-methyl-2-[[1-methyl-2-oxo-5-(trifluoromethyl)-3-pyridinyl]amino]imidazo[4,5-b]pyridin-6-yl]oxy-2-pyridinyl]-1,1-dimethylurea"	""	""	"C(#N)C1=C2C(=NC=C1OC3=CC(=NC=C3)NC(N(C)C)=O)N=C(N2C)NC=4C(N(C=C(C4)C(F)(F)F)C)=O"	"RREYQWVDIVFTGS-UHFFFAOYSA-N"	"InChI=1S/C23H20F3N9O3/c1-33(2)22(37)31-17-8-13(5-6-28-17)38-16-10-29-19-18(14(16)9-27)35(4)21(32-19)30-15-7-12(23(24,25)26)11-34(3)20(15)36/h5-8,10-11H,1-4H3,(H,28,31,37)(H,29,30,32)"	"yes"	""	""
"9961"	"compound 20f [PMID: 28520415]"	""	"Synthetic organic"	""	""	""	""	"374883848"	"134611885"	""	""	""	""	""	""	""	"4-amino-6-{[(1S)-1-{3-methyl-6-[3-({4-[methyl(2-methylpropyl)amino]piperidin-1-yl}methyl)phenyl]-5-oxo-5H-[1,3]thiazolo[3,2-a]pyridin-7-yl}ethyl]amino}pyrimidine-5-carbonitrile"	""	""	"N#Cc1c(ncnc1N)N[C@H](c1cc2scc(n2c(=O)c1c1cccc(c1)CN1CCC(CC1)N(CC(C)C)C)C)C"	"ZUQSHQGUCXJKSV-QFIPXVFZSA-N"	"InChI=1S/C32H40N8OS/c1-20(2)16-38(5)25-9-11-39(12-10-25)17-23-7-6-8-24(13-23)29-26(14-28-40(32(29)41)21(3)18-42-28)22(4)37-31-27(15-33)30(34)35-19-36-31/h6-8,13-14,18-20,22,25H,9-12,16-17H2,1-5H3,(H3,34,35,36,37)/t22-/m0/s1"	"yes"	""	""
"10403"	"compound 21b [PMID: 31136173]"	""	"Synthetic organic"	""	""	""	""	"384403682"	"138393295"	""	""	""	""	""	""	""	"3-{2-[5-(3,4-dimethoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]ethynyl}pyridine"	""	""	"COc1cc(ccc1OC)c1cnc2c(c1)c(C#Cc1cccnc1)c[nH]2"	"CJTVDIBZBUWIFC-UHFFFAOYSA-N"	"InChI=1S/C22H17N3O2/c1-26-20-8-7-16(11-21(20)27-2)18-10-19-17(13-24-22(19)25-14-18)6-5-15-4-3-9-23-12-15/h3-4,7-14H,1-2H3,(H,24,25)"	"yes"	""	""
"6918"	"compound 21 [PMID: 22802221]"	""	"Synthetic organic"	""	""	""	""	"178103500"	"9804984"	""	""	"CHEMBL189568"	""	""	""	""	"butyl N-[3-[4-(imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophen-2-yl]sulfonylcarbamate"	""	"3-[4-(1H-imidazol-1-ylmethyl)phenyl]-5-(2-methylpropyl)thiophene-2-[(N-butyloxylcarbamate)-sulphonamide] sodium salt|C21"	"CCCCOC(=O)NS(=O)(=O)c1sc(cc1c1ccc(cc1)Cn1cncc1)CC(C)C"	"XTEOJPUYZWEXFI-UHFFFAOYSA-N"	"InChI=1S/C23H29N3O4S2/c1-4-5-12-30-23(27)25-32(28,29)22-21(14-20(31-22)13-17(2)3)19-8-6-18(7-9-19)15-26-11-10-24-16-26/h6-11,14,16-17H,4-5,12-13,15H2,1-3H3,(H,25,27)"	"yes"	""	""
"8187"	"compound 21 [PMID: 24900635]"	""	"Synthetic organic"	""	""	""	""	"249565867"	"76332060"	""	""	"CHEMBL3109212"	""	""	""	""	"1-[3-[5-(3-aminophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea"	""	""	"O=C(Nc1cc(ccc1F)C(F)(F)F)Nc1cccc(c1)c1c[nH]c2c1cc(cn2)c1cccc(c1)N"	"QQTPMHCXBYRWFQ-UHFFFAOYSA-N"	"InChI=1S/C27H19F4N5O/c28-23-8-7-18(27(29,30)31)12-24(23)36-26(37)35-20-6-2-4-16(10-20)22-14-34-25-21(22)11-17(13-33-25)15-3-1-5-19(32)9-15/h1-14H,32H2,(H,33,34)(H2,35,36,37)"	"yes"	""	""
"9252"	"compound 24 [PMID: 26987013 ]"	""	"Synthetic organic"	""	""	""	""	"315661327"	"118197428"	""	""	""	""	""	""	""	"4-tert-butyl-N-[7-chloro-2-(2-methyl-1-oxidopyridin-1-ium-3-yl)-1,3-dioxoisoindol-4-yl]benzenesulfonamide"	""	""	"O=C1c2c(ccc(c2C(=O)N1c1ccc[n+](c1C)[O-])Cl)NS(=O)(=O)c1ccc(cc1)C(C)(C)C"	"SEZYEWZALINSCW-UHFFFAOYSA-N"	"InChI=1S/C24H22ClN3O5S/c1-14-19(6-5-13-27(14)31)28-22(29)20-17(25)11-12-18(21(20)23(28)30)26-34(32,33)16-9-7-15(8-10-16)24(2,3)4/h5-13,26H,1-4H3"	"yes"	""	""
"9700"	"compound 25 [PMID: 28038940]"	""	"Synthetic organic"	""	""	""	""	"348353659"	"131801161"	""	""	""	""	""	""	""	"N-{2-[(5-chloro-2-{[1-(2-methoxyethyl)-1H-pyrazol-4-yl]amino}pyrimidin-4-yl)oxy]phenyl}prop-2-enamide"	""	""	"COCCn1ncc(c1)Nc1ncc(c(n1)Oc1ccccc1NC(=O)C=C)Cl"	"ORBLOJJZDLUQDF-UHFFFAOYSA-N"	"InChI=1S/C19H19ClN6O3/c1-3-17(27)24-15-6-4-5-7-16(15)29-18-14(20)11-21-19(25-18)23-13-10-22-26(12-13)8-9-28-2/h3-7,10-12H,1,8-9H2,2H3,(H,24,27)(H,21,23,25)"	"yes"	""	""
"10428"	"compound 25 [PMID: 31260299]"	""	"Synthetic organic"	""	""	""	""	"385612188"	"139030520"	""	""	""	""	""	""	""	"4-Amino-5-fluoro-8-(5-methoxy-1H-indazol-6-yl)quinoline-3-carboxamide"	""	""	"COc1cc2cn[nH]c2cc1c1ccc(c2c1ncc(c2N)C(=O)N)F"	"RFCJOYPMBVRHBV-UHFFFAOYSA-N"	"InChI=1S/C18H14FN5O2/c1-26-14-4-8-6-23-24-13(8)5-10(14)9-2-3-12(19)15-16(20)11(18(21)25)7-22-17(9)15/h2-7H,1H3,(H2,20,22)(H2,21,25)(H,23,24)"	"yes"	""	""
"10718"	"compound 25 [PMID: 32105470]"	""	"Synthetic organic"	""	""	""	""	"405067312"	"146025594"	""	""	""	""	""	""	""	"2-Chloro-N-(3-(morpholinosulfonyl)-4-(trifluoromethyl)phenyl)acetamide"	""	""	"ClCC(=O)Nc1ccc(c(c1)S(=O)(=O)N1CCOCC1)C(F)(F)F"	"XVPZEJHHJYHMIV-UHFFFAOYSA-N"	"InChI=1S/C13H14ClF3N2O4S/c14-8-12(20)18-9-1-2-10(13(15,16)17)11(7-9)24(21,22)19-3-5-23-6-4-19/h1-2,7H,3-6,8H2,(H,18,20)"	"yes"	""	""
"11130"	"compound 25 [PMID: 32687365]"	""	"Synthetic organic"	""	""	""	""	"434122190"	"154699446"	""	""	""	""	""	""	""	"2-(4-((2-Chloro-4-((3-(2,6-dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)benzyl)amino)phenyl)acetic acid"	""	""	"OC(=O)Cc1ccc(cc1)NCc1ccc(cc1Cl)OCc1c(onc1c1c(Cl)cccc1Cl)C(C)C"	"SPZFHDGEKBUECT-UHFFFAOYSA-N"	"InChI=1S/C28H25Cl3N2O4/c1-16(2)28-21(27(33-37-28)26-22(29)4-3-5-23(26)30)15-36-20-11-8-18(24(31)13-20)14-32-19-9-6-17(7-10-19)12-25(34)35/h3-11,13,16,32H,12,14-15H2,1-2H3,(H,34,35)"	"yes"	""	""
"10643"	"compound 25 [Zhang <i>et a</i>l., 2020]"	""	"Synthetic organic"	""	""	""	""	"404859090"	"72943563"	""	""	""	""	""	""	""	"(3S,4R)-1-[1-(2-chloro-6-cyclopropylbenzoyl)-4-fluoro-1H-indazol-3-yl]-3-hydroxypiperidine-4-carboxylic acid"	""	"example 6B [WO2014028600A2]"	"OC(=O)[C@@H]1CCN(C[C@H]1O)c1nn(c2c1c(F)ccc2)C(=O)c1c(Cl)cccc1C1CC1"	"IBIKHMZPHNKTHM-RDTXWAMCSA-N"	"InChI=1S/C23H21ClFN3O4/c24-15-4-1-3-13(12-7-8-12)19(15)22(30)28-17-6-2-5-16(25)20(17)21(26-28)27-10-9-14(23(31)32)18(29)11-27/h1-6,12,14,18,29H,7-11H2,(H,31,32)/t14-,18-/m1/s1"	"yes"	""	""
"10602"	"compound 26 [PMID: 31710475]"	""	"Synthetic organic"	""	""	""	""	"404859049"	"142411827"	""	""	""	""	""	""	""	""	""	""	"CN(CCn1ncc(c1)c1ccc2c(c1)C(=O)Nc1cccc(n1)c1n(CCCCO2)cnn1)C"	"JGKCBXMHIQSQHJ-UHFFFAOYSA-N"	"InChI=1S/C25H28N8O2/c1-31(2)11-12-33-16-19(15-27-33)18-8-9-22-20(14-18)25(34)29-23-7-5-6-21(28-23)24-30-26-17-32(24)10-3-4-13-35-22/h5-9,14-17H,3-4,10-13H2,1-2H3,(H,28,29,34)"	"yes"	""	""
"10133"	"compound 27 [PMID: 24900635]"	""	"Synthetic organic"	""	""	""	""	"381118843"	"10113568"	""	""	"CHEMBL247228"	""	""	""	""	"1-[4-(4-aminofuro[2,3-d]pyrimidin-5-yl)phenyl]-3-[2-fluoro-5-(trifluoromethyl)phenyl]urea"	""	""	"O=C(Nc1cc(ccc1F)C(F)(F)F)Nc1ccc(cc1)c1coc2c1c(N)ncn2"	"KNDPXYAMINMLED-UHFFFAOYSA-N"	"InChI=1S/C20H13F4N5O2/c21-14-6-3-11(20(22,23)24)7-15(14)29-19(30)28-12-4-1-10(2-5-12)13-8-31-18-16(13)17(25)26-9-27-18/h1-9H,(H2,25,26,27)(H2,28,29,30)"	"yes"	""	""
"9670"	"compound 28 [PMID: 28671460]"	""	"Synthetic organic"	""	""	""	""	"348353629"	"2835211"	""	""	"CHEMBL581893"	""	""	""	""	"2-(7-methoxy-4-methylquinazolin-2-yl)guanidine"	""	""	"COc1ccc2c(c1)nc(nc2C)N=C(N)N"	"ZJBMSSBTCGJZEE-UHFFFAOYSA-N"	"InChI=1S/C11H13N5O/c1-6-8-4-3-7(17-2)5-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16)"	"yes"	""	""
"9992"	"compound 29 [Moslin <i>et al</i>., 2017]"	""	"Synthetic organic"	""	""	""	""	"374883879"	"134611892"	""	""	""	""	""	""	""	"6-[(3,5-difluoro-2-methoxyphenyl)amino]-N-(3,4-dihydroxy-3-methylbutyl)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide"	""	""	"COc1c(cc(cc1F)F)Nc1cc(NC)c2n(n1)c(cn2)C(=O)NCCC(CO)(O)C"	"BDYFCJQKSYBTAK-UHFFFAOYSA-N"	"InChI=1S/C20H24F2N6O4/c1-20(31,10-29)4-5-24-19(30)15-9-25-18-14(23-2)8-16(27-28(15)18)26-13-7-11(21)6-12(22)17(13)32-3/h6-9,23,29,31H,4-5,10H2,1-3H3,(H,24,30)(H,26,27)"	"yes"	""	""
"10596"	"compound 29 [PMID: 31934767]"	""	"Synthetic organic"	""	""	""	""	"404859043"	"145996526"	""	""	""	""	""	""	""	"3-((2-Amino-5-(1-methyl-1H-pyrazol-4-yl)pyridin-3-yl)ethynyl)-N-(4-chlorophenyl)-4-methylbenzamide"	""	""	"Clc1ccc(cc1)NC(=O)c1ccc(c(c1)C#Cc1cc(cnc1N)c1cnn(c1)C)C"	"JZKQBPWOWAPASE-UHFFFAOYSA-N"	"InChI=1S/C25H20ClN5O/c1-16-3-4-19(25(32)30-23-9-7-22(26)8-10-23)11-17(16)5-6-18-12-20(13-28-24(18)27)21-14-29-31(2)15-21/h3-4,7-15H,1-2H3,(H2,27,28)(H,30,32)"	"yes"	""	""
"9682"	"compound 2g [PMID: 27390066]"	""	"Synthetic organic"	""	""	""	""	"348353641"	"118720630"	""	""	"CHEMBL3355101"	""	""	""	""	"2-[[[1-amino-3-(4-nitrophenyl)propyl]-hydroxyphosphoryl]methyl]-3-phenylpropanoic acid"	""	""	"OC(=O)C(CP(=O)(C(CCc1ccc(cc1)[N+](=O)[O-])N)O)Cc1ccccc1"	"YSYQXQQIKOEBNN-UHFFFAOYSA-N"	"InChI=1S/C19H23N2O6P/c20-18(11-8-14-6-9-17(10-7-14)21(24)25)28(26,27)13-16(19(22)23)12-15-4-2-1-3-5-15/h1-7,9-10,16,18H,8,11-13,20H2,(H,22,23)(H,26,27)"	"yes"	""	""
"11282"	"compound 2 [PMID: 28621538]"	""	"Synthetic organic"	""	""	""	""	"434321717"	"86673884"	""	""	"CHEMBL3683753"	""	""	""	""	"1-[2-[(1R,3S,5R)-3-[(6-bromopyridin-2-yl)carbamoyl]-2-azabicyclo[3.1.0]hexan-2-yl]-2-oxoethyl]indazole-3-carboxamide"	""	"example 727 [WO2012093101A1]"	"Brc1cccc(n1)NC(=O)[C@@H]1C[C@@H]2[C@H](N1C(=O)Cn1nc(c3c1cccc3)C(=O)N)C2"	"CWZUTHDJLNZLCM-DFBGVHRSSA-N"	"InChI=1S/C21H19BrN6O3/c22-16-6-3-7-17(24-16)25-21(31)15-9-11-8-14(11)28(15)18(29)10-27-13-5-2-1-4-12(13)19(26-27)20(23)30/h1-7,11,14-15H,8-10H2,(H2,23,30)(H,24,25,31)/t11-,14-,15+/m1/s1"	"yes"	""	""
"10365"	"compound 2q [PMID: 30986068]"	""	"Synthetic organic"	""	""	""	""	"384403645"	"118556943"	""	""	""	""	""	""	""	"[(3S)-3-[8-(1-ethyl-5-methylpyrazol-4-yl)-9-methylpurin-6-yl]oxypyrrolidin-1-yl]-(oxan-4-yl)methanone"	""	"example 2-8 [US20150353552]"	"CCn1ncc(c1C)c1nc2c(n1C)ncnc2O[C@H]1CCN(C1)C(=O)C1CCOCC1"	"FHKPLLOSJHHKNU-INIZCTEOSA-N"	"InChI=1S/C22H29N7O3/c1-4-29-14(2)17(11-25-29)19-26-18-20(27(19)3)23-13-24-21(18)32-16-5-8-28(12-16)22(30)15-6-9-31-10-7-15/h11,13,15-16H,4-10,12H2,1-3H3/t16-/m0/s1"	"yes"	""	""
"14502"	"compound 30k [PMID: 42046270]"	""	"Synthetic organic"	""	""	""	""	""	""	""	""	""	""	""	""	""	"5-(N-((3′-Chloro-[1,1′-biphenyl]-4-yl)methyl)-N-(4-((4-hydroxyphenyl)ethynyl)phenyl)sulfamoyl)benzofuran-2-carboxylic Acid"	""	""	"OC=1C=CC(=CC1)C#CC2=CC=C(N(CC3=CC=C(C4=CC(Cl)=CC=C4)C=C3)S(C5=CC=C6OC(C(O)=O)=CC6=C5)(=O)=O)C=C2"	"BPVYOYDZOCOMSL-UHFFFAOYSA-N"	"InChI=1S/C36H24ClNO6S/c37-30-3-1-2-28(20-30)27-12-6-26(7-13-27)23-38(31-14-8-24(9-15-31)4-5-25-10-16-32(39)17-11-25)45(42,43)33-18-19-34-29(21-33)22-35(44-34)36(40)41/h1-3,6-22,39H,23H2,(H,40,41)"	"yes"	""	""
"10417"	"compound 31 [PMID: 31259550]"	""	"Synthetic organic"	""	""	""	""	"385612177"	"134324842"	""	""	""	""	""	""	""	"1-[(1R)-1-(2,4-Dichlorophenyl)ethyl]-6-[(4S,5R)-4-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]-5-methylcyclohexen-1-yl]pyrazolo[3,4-b]pyrazine-3-carbonitrile"	""	""	"OC[C@@H]1CCCN1[C@H]1CC=C(C[C@H]1C)c1cnc2c(n1)n(nc2C#N)[C@@H](c1ccc(cc1Cl)Cl)C"	"KQZLRWGGWXJPOS-NLFPWZOASA-N"	"InChI=1S/C26H28Cl2N6O/c1-15-10-17(5-8-24(15)33-9-3-4-19(33)14-35)23-13-30-25-22(12-29)32-34(26(25)31-23)16(2)20-7-6-18(27)11-21(20)28/h5-7,11,13,15-16,19,24,35H,3-4,8-10,14H2,1-2H3/t15-,16-,19+,24+/m1/s1"	"yes"	""	""
"10528"	"compound 32 [PMID: 31638797]"	""	"Synthetic organic"	""	""	""	""	"387065610"	"122669265"	""	""	""	""	""	""	""	"[(3aR,9bR)-9b-(4-fluorophenyl)sulfonyl-7-(1,1,1,2,3,3,3-heptafluoropropan-2-yl)-2,3a,4,5-tetrahydro-1H-benzo[e]indol-3-yl]-(4-hydroxy-1,1-dioxothian-4-yl)methanone"	""	"example 69 [WO2016179460A1]"	"Fc1ccc(cc1)S(=O)(=O)[C@@]12CCN([C@@H]1CCc1c2ccc(c1)C(C(F)(F)F)(C(F)(F)F)F)C(=O)C1(O)CCS(=O)(=O)CC1"	"ONXFNBOZJKXCNC-ZJSXRUAMSA-N"	"InChI=1S/C27H25F8NO6S2/c28-18-3-5-19(6-4-18)44(41,42)24-9-12-36(22(37)23(38)10-13-43(39,40)14-11-23)21(24)8-1-16-15-17(2-7-20(16)24)25(29,26(30,31)32)27(33,34)35/h2-7,15,21,38H,1,8-14H2/t21-,24-/m1/s1"	"yes"	""	""
"13050"	"compound 32 [PMID: 38047891]"	""	"Synthetic organic"	""	""	""	""	"491299832"	"169494480"	""	""	""	""	""	""	""	"(2E)-3-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)-1-[4-(2-methoxypyrimidine-5-carbonyl)piperazin-1-yl]prop-2-en-1-one"	""	""	"FC1(OC2=C(O1)C=CC(=C2)/C=C/C(N3CCN(C(C4=CN=C(OC)N=C4)=O)CC3)=O)F"	"VLODLHKKDGGSJO-HWKANZROSA-N"	"InChI=1S/C20H18F2N4O5/c1-29-19-23-11-14(12-24-19)18(28)26-8-6-25(7-9-26)17(27)5-3-13-2-4-15-16(10-13)31-20(21,22)30-15/h2-5,10-12H,6-9H2,1H3/b5-3+"	"yes"	""	""
"9391"	"compound 36 [PMID: 21958547]"	""	"Synthetic organic"	""	""	""	""	"328083493"	"124037381"	""	""	""	""	""	""	""	""	""	""	"CN(C/C=C/C(=O)N(C1CC2C(CC1F)N=C(c1n2cnc1)Nc1ccccc1C)C)C"	"KJDBCEWMSRFWQY-JXMROGBWSA-N"	"InChI=1S/C24H31FN6O/c1-16-8-5-6-9-18(16)27-24-22-14-26-15-31(22)21-13-20(17(25)12-19(21)28-24)30(4)23(32)10-7-11-29(2)3/h5-10,14-15,17,19-21H,11-13H2,1-4H3,(H,27,28)/b10-7+"	"yes"	""	""
"9797"	"compound 37 [PMID: 29193967]"	""	"Synthetic organic"	""	""	""	""	"354702269"	"132427687"	""	""	""	""	""	""	""	""	""	""	"N#Cc1cc(ccc1Oc1ccc(c(c1)C(F)(F)F)Cl)NS(=O)(=O)c1ccc(cc1)N"	"GADGQEKPNKSGMT-UHFFFAOYSA-N"	"InChI=1S/C20H13ClF3N3O3S/c21-18-7-4-15(10-17(18)20(22,23)24)30-19-8-3-14(9-12(19)11-25)27-31(28,29)16-5-1-13(26)2-6-16/h1-10,27H,26H2"	"yes"	""	""
"10585"	"compound 39 [PMID: 31742400]"	""	"Synthetic organic"	""	""	""	""	"404859032"	"145996522"	""	""	""	""	""	""	""	"2-Amino-6-(2,3-dichlorobenzyl)-5-isopropyl[1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one"	""	""	"Nc1nn2c(n1)[nH]c(c(c2=O)Cc1cccc(c1Cl)Cl)C(C)C"	"KLBHHUODQVCBKX-UHFFFAOYSA-N"	"InChI=1S/C15H15Cl2N5O/c1-7(2)12-9(6-8-4-3-5-10(16)11(8)17)13(23)22-15(19-12)20-14(18)21-22/h3-5,7H,6H2,1-2H3,(H3,18,19,20,21)"	"yes"	""	""
"9965"	"compound 3a [Pipionne <i>et al</i>, 2018]"	""	"Synthetic organic"	""	""	""	""	"374883852"	"134611886"	""	""	""	""	""	""	""	"1-[5-amino-4-(3,4-dichlorophenyl)-3-methyl-1H-pyrazol-1-yl]ethan-1-one"	""	""	"Cc1nn(c(c1c1ccc(c(c1)Cl)Cl)N)C(=O)C"	"HJXDCOSNNVYHCY-UHFFFAOYSA-N"	"InChI=1S/C12H11Cl2N3O/c1-6-11(12(15)17(16-6)7(2)18)8-3-4-9(13)10(14)5-8/h3-5H,15H2,1-2H3"	"yes"	""	""
"10591"	"compound 3c [PMID: 30360354]"	""	"Peptide"	""	""	""	""	"404859038"	"145996524"	""	""	""	""	""	""	""	"(2S)-6-amino-2-[(2R)-2-({[(2S)-2-[(2R)-2-[(2S)-2-amino-3-(1H-imidazol-4-yl)propanamido]-3-(1H-indol-3-yl)propanamido]-N'-[(4-fluorocyclohexyl)methyl]propanehydrazido]sulfonyl}amino)-3-phenylpropanamido]hexanamide"	""	"[As(4-F)F4]-GHRP-6|azasulfuryl-p-fluorophenylalanine-4-[As(4-F)F<sup>4</sup>]-GHRP-6|H-His-D-Trp-Ala-(4-F)AsF-D-Phe-Lys-NH2"	"NCCCC[C@@H](C(=O)N)NC(=O)[C@H](NS(=O)(=O)N(NC(=O)[C@@H](NC(=O)[C@@H](Cc1c[nH]c2c1cccc2)NC(=O)[C@H](Cc1c[nH]cn1)N)C)CC1CCC(CC1)F)Cc1ccccc1"	"WYIBLRVRRGCPGV-FQYZGFJBSA-N"	"InChI=1S/C42H59FN12O7S/c1-26(50-41(59)36(20-29-22-48-34-12-6-5-11-32(29)34)52-40(58)33(45)21-31-23-47-25-49-31)39(57)53-55(24-28-14-16-30(43)17-15-28)63(61,62)54-37(19-27-9-3-2-4-10-27)42(60)51-35(38(46)56)13-7-8-18-44/h2-6,9-12,22-23,25-26,28,30,33,35-37,48,54H,7-8,13-21,24,44-45H2,1H3,(H2,46,56)(H,47,49)(H,50,59)(H,51,60)(H,52,58)(H,53,57)/t26-,28?,30?,33-,35-,36+,37+/m0/s1"	"yes"	""	""
"9628"	"compound 3 [PMID: 28603634]"	""	"Synthetic organic"	""	""	""	""	"340590258"	"91810751"	""	""	""	""	""	""	""	"3-[[6-[3-(hydroxymethyl)phenyl]-3-methylpyridine-2-carbonyl]amino]-2,4-dimethylbenzoic acid"	""	""	"OCc1cccc(c1)c1ccc(c(n1)C(=O)Nc1c(C)ccc(c1C)C(=O)O)C"	"WRBLOVAXQYYLFM-UHFFFAOYSA-N"	"InChI=1S/C23H22N2O4/c1-13-7-9-18(23(28)29)15(3)20(13)25-22(27)21-14(2)8-10-19(24-21)17-6-4-5-16(11-17)12-26/h4-11,26H,12H2,1-3H3,(H,25,27)(H,28,29)"	"yes"	""	""
"9960"	"compound 3 [PMID: 29633584]"	""	"Synthetic organic"	""	""	""	""	"374883847"	"134611884"	""	""	""	""	""	""	""	"3-(2,4-dimethoxypyrimidin-5-yl)quinoline-5,8-dicarboxylic acid"	""	""	"COc1nc(OC)ncc1c1cnc2c(c1)c(ccc2C(=O)O)C(=O)O"	"CAGSRYBLIZYFGG-UHFFFAOYSA-N"	"InChI=1S/C17H13N3O6/c1-25-14-12(7-19-17(20-14)26-2)8-5-11-9(15(21)22)3-4-10(16(23)24)13(11)18-6-8/h3-7H,1-2H3,(H,21,22)(H,23,24)"	"yes"	""	""
"9683"	"compound 3v [PMID: 27390066]"	""	"Synthetic organic"	""	""	""	""	"348353642"	"127052870"	""	""	"CHEMBL3806197"	""	""	""	""	"[1-amino-2-[2-(4-methoxyphenyl)ethylamino]ethyl]phosphonic acid"	""	""	"COc1ccc(cc1)CCNCC(P(=O)(O)O)N"	"HFIVLLBFACNAFN-UHFFFAOYSA-N"	"InChI=1S/C11H19N2O4P/c1-17-10-4-2-9(3-5-10)6-7-13-8-11(12)18(14,15)16/h2-5,11,13H,6-8,12H2,1H3,(H2,14,15,16)"	"yes"	""	""
"9349"	"compound 41 [PMID: 25000588]"	""	"Synthetic organic"	""	""	""	""	"328083451"	"76285722"	""	""	""	""	""	""	""	"(1R)-1-methyl-9-[(3-methylazetidin-3-yl)amino]-8-(trifluoromethyl)-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one"	""	""	"O=C1NN=C2N([C@@H]1C)c1cc(NC3(C)CNC3)c(cc1OC2)C(F)(F)F"	"OUZPGLCFBNPQPF-MRVPVSSYSA-N"	"InChI=1S/C16H18F3N5O2/c1-8-14(25)23-22-13-5-26-12-3-9(16(17,18)19)10(4-11(12)24(8)13)21-15(2)6-20-7-15/h3-4,8,20-21H,5-7H2,1-2H3,(H,23,25)/t8-/m1/s1"	"yes"	""	""
"10598"	"compound 41 [PMID: 31855425]"	""	"Synthetic organic"	""	""	""	""	"404859045"	"145946093"	""	""	""	""	""	""	""	"(R)-2-Methoxy-N-(2-methoxy-5-(7-((4-(oxetan-3-yl)morpholin-2-yl)methoxy)-1,3-dihydroisobenzofuran-5-yl)pyridin-3-yl)ethanesulfonamide"	""	""	"COCCS(=O)(=O)Nc1cc(cnc1OC)c1cc(OC[C@@H]2OCCN(C2)C2COC2)c2c(c1)COC2"	"ZWPJBXLFZFLGMV-OAQYLSRUSA-N"	"InChI=1S/C25H33N3O8S/c1-31-5-6-37(29,30)27-23-8-18(10-26-25(23)32-2)17-7-19-12-33-16-22(19)24(9-17)36-15-21-11-28(3-4-35-21)20-13-34-14-20/h7-10,20-21,27H,3-6,11-16H2,1-2H3/t21-/m1/s1"	"yes"	""	""
"9492"	"compound 43 [PMID: 26751273]"	""	"Synthetic organic"	""	""	""	""	"329968432"	"49848557"	""	""	""	""	""	""	""	"3-[2-[5-(3-chloro-4-propan-2-yloxyphenyl)-1,3,4-thiadiazol-2-yl]-3-methyl-6,7-dihydro-4H-pyrazolo[4,3-c]pyridin-5-yl]propanoic acid"	""	""	"OC(=O)CCN1CCc2c(C1)c(C)n(n2)c1nnc(s1)c1ccc(c(c1)Cl)OC(C)C"	"BGAJNPLDJJBRHK-UHFFFAOYSA-N"	"InChI=1S/C21H24ClN5O3S/c1-12(2)30-18-5-4-14(10-16(18)22)20-23-24-21(31-20)27-13(3)15-11-26(9-7-19(28)29)8-6-17(15)25-27/h4-5,10,12H,6-9,11H2,1-3H3,(H,28,29)"	"yes"	""	""
"9646"	"compound 47 [PMID: 28737909]"	""	"Synthetic organic"	""	""	""	""	"340590276"	"129320519"	""	""	""	""	""	""	""	"2-Amino-4-(4-hydroxymethyl)phenyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile"	""	""	"OCc1ccc(cc1)c1nc(N)nc2c1c(C#N)c[nH]2"	"BJQSJIPGTMBHKF-UHFFFAOYSA-N"	"InChI=1S/C14H11N5O/c15-5-10-6-17-13-11(10)12(18-14(16)19-13)9-3-1-8(7-20)2-4-9/h1-4,6,20H,7H2,(H3,16,17,18,19)"	"yes"	""	""
"5531"	"compound 48/80"	""	"Synthetic organic"	""	""	""	""	"178102173"	"2855"	""	""	""	""	""	""	""	"2-[4-methoxy-3,5-bis[[2-methoxy-5-(2-methylaminoethyl)phenyl]methyl]phenyl]-N-methylethanamine"	""	""	"CNCCc1cc(Cc2cc(CCNC)ccc2OC)c(c(c1)Cc1cc(CCNC)ccc1OC)OC"	"DXEVTBAWIGXNAW-UHFFFAOYSA-N"	"InChI=1S/C32H45N3O3/c1-33-14-11-23-7-9-30(36-4)26(17-23)21-28-19-25(13-16-35-3)20-29(32(28)38-6)22-27-18-24(12-15-34-2)8-10-31(27)37-5/h7-10,17-20,33-35H,11-16,21-22H2,1-6H3"	"yes"	""	""
"12355"	"compound 49 [PMID: 36529947]"	""	"Synthetic organic"	""	""	""	""	"479821146"	"146276619"	""	""	""	""	""	""	""	"2-[[(2R,3S,4R,5R)-5-(6-amino-2-chloropurin-9-yl)-3-ethynyl-3,4-dihydroxyoxolan-2-yl]methoxy]-2-[[4-(2-oxo-1,3-diazinan-1-yl)phenyl]methyl]propanedioic acid"	""	""	"Clc1nc(N)c2c(n1)n(cn2)[C@H]1[C@H](O)[C@@](O)(C#C)[C@@H](COC(C(=O)O)(Cc2ccc(N3C(=O)NCCC3)cc2)C(=O)O)O1"	"ROWSPNRRBJYDCU-IRJNKLFQSA-N"	"InChI=1S/C26H26ClN7O9/c1-2-25(41)15(43-20(17(25)35)34-12-30-16-18(28)31-23(27)32-19(16)34)11-42-26(21(36)37,22(38)39)10-13-4-6-14(7-5-13)33-9-3-8-29-24(33)40/h1,4-7,12,15,17,20,35,41H,3,8-11H2,(H,29,40)(H,36,37)(H,38,39)(H2,28,31,32)/t15-,17+,20-,25-/m1/s1"	"yes"	""	""
"12122"	"compound 4e [PMID: 35546685]"	""	"Synthetic organic"	""	""	""	""	"472319244"	"89612265"	""	""	""	""	""	""	""	"1-[5-tert-butyl-2-[1-[2-(dimethylamino)ethyl]pyrazol-4-yl]pyrazol-3-yl]-3-[(1S,4R)-4-[[3-[(2S)-2-methylpiperidin-1-yl]-[1,2,4]triazolo[4,3-a]pyridin-6-yl]oxy]-1,2,3,4-tetrahydronaphthalen-1-yl]urea"	""	"CHF-6297|CHF6297|CHI 91040|CHI91040|p38&alpha; MAPK-IN-5"	"O=C(Nc1cc(C(C)(C)C)nn1c1cn(CCN(C)C)nc1)N[C@H]1CC[C@@H](Oc2ccc3n(c2)c(nn3)N2[C@@H](C)CCCC2)c2c1cccc2"	"PPZSTJQLZOPKBO-LGXAAPQCSA-N"	"InChI=1S/C37H49N11O2/c1-25-11-9-10-18-46(25)36-42-41-33-17-14-27(24-47(33)36)50-31-16-15-30(28-12-7-8-13-29(28)31)39-35(49)40-34-21-32(37(2,3)4)43-48(34)26-22-38-45(23-26)20-19-44(5)6/h7-8,12-14,17,21-25,30-31H,9-11,15-16,18-20H2,1-6H3,(H2,39,40,49)/t25-,30-,31+/m0/s1"	"yes"	""	""
"9198"	"compound 4g [PMID: 2680437]"	""	"Synthetic organic"	""	""	""	""	"340590210"	"121486665"	""	""	""	""	""	""	""	"3-{[1-(2-chlorophenyl)-1H-1,2,3-triazol-4-yl]methyl}-2H,3H-[1,3]oxazolo[4,5-b]pyridin-2-one"	""	""	"O=c1oc2c(n1Cc1nnn(c1)c1ccccc1Cl)nccc2"	"DVUFHXDFLFFOFE-UHFFFAOYSA-N"	"InChI=1S/C15H10ClN5O2/c16-11-4-1-2-5-12(11)21-9-10(18-19-21)8-20-14-13(23-15(20)22)6-3-7-17-14/h1-7,9H,8H2"	"yes"	""	""
"10001"	"compound 52 [PMID: 28541707]"	""	"Synthetic organic"	""	""	""	""	"374883888"	"132220479"	""	""	""	""	""	""	""	""	""	""	"N#Cc1ccc(cc1N1CCN(C(C1=O)(C)C)C(=O)C)c1cc(c2n1ncnc2N)C(F)(F)F"	"ZDXIDBRGTYDHBQ-UHFFFAOYSA-N"	"InChI=1S/C22H20F3N7O2/c1-12(33)31-7-6-30(20(34)21(31,2)3)16-8-13(4-5-14(16)10-26)17-9-15(22(23,24)25)18-19(27)28-11-29-32(17)18/h4-5,8-9,11H,6-7H2,1-3H3,(H2,27,28,29)"	"yes"	""	""
"13913"	"compound 52 [PMID: 32902255]"	""	"Synthetic organic"	""	""	""	""	"513757598"	"136164931"	""	""	"CHEMBL5266734"	""	""	""	""	""	""	"IL-4 inhibitor 4"	"NC1=C(C#N)C(=CC(=N1)C2=CC=C(F)C=C2)C3=CC(O)=C(O)C=C3"	"DWZPPBGRCDPFSS-UHFFFAOYSA-N"	"InChI=1S/C18H12FN3O2/c19-12-4-1-10(2-5-12)15-8-13(14(9-20)18(21)22-15)11-3-6-16(23)17(24)7-11/h1-8,23-24H,(H2,21,22)"	"yes"	""	""
"14529"	"compound 56 [PMID: 42143779]"	""	"Synthetic organic"	""	""	""	""	""	""	""	""	""	""	""	""	""	"(E)-3-((1-((3-((5-((3-Acetamidophenyl)carbamoyl)-2-(5-acetylthiophen-2-yl)pyrimidin-4-yl)amino)propyl)amino)-2-nitrovinyl)amino)propanoic Acid"	""	""	"C(C)(=O)NC=1C=C(C=CC1)NC(=O)C=2C(=NC(=NC2)C=3SC(=CC3)C(C)=O)NCCCN/C(=C\[N+](=O)[O-])/NCCC(=O)O"	"ITPOIRGHONOVAB-HZHRSRAPSA-N"	"InChI=1S/C27H30N8O7S/c1-16(36)21-7-8-22(43-21)26-31-14-20(27(40)33-19-6-3-5-18(13-19)32-17(2)37)25(34-26)30-11-4-10-28-23(15-35(41)42)29-12-9-24(38)39/h3,5-8,13-15,28-29H,4,9-12H2,1-2H3,(H,32,37)(H,33,40)(H,38,39)(H,30,31,34)/b23-15+"	"yes"	""	""
"9835"	"compound 5b [PMID: 29457898]"	""	"Synthetic organic"	""	""	""	""	"363894129"	"133081956"	""	""	""	""	""	""	""	"Benzyl ((((E)-4-((tert-Butyldimethylsilyl)oxy)-3-methylbut-2-en-1-yl)oxy)(phenoxy)phosphoryl)-L-alaninate"	""	""	"C/C(=C\COP(=O)(N[C@H](C(=O)OCc1ccccc1)C)Oc1ccccc1)/CO[Si](C(C)(C)C)(C)C"	"OAOYKSGPQULCDH-WHZCJLAPSA-N"	"InChI=1S/C27H40NO6PSi/c1-22(20-33-36(6,7)27(3,4)5)18-19-32-35(30,34-25-16-12-9-13-17-25)28-23(2)26(29)31-21-24-14-10-8-11-15-24/h8-18,23H,19-21H2,1-7H3,(H,28,30)/b22-18+/t23-,35?/m0/s1"	"yes"	""	""
"10434"	"compound 5b  [PMID: 31287314]"	""	"Synthetic organic"	""	""	""	""	"385612194"	""	""	""	""	""	""	""	""	""	""	""	"O#C[Co]1(C#O)(C#O)C2C1([Co]2(C#O)(C#O)C#O)CNC3=CC=C(C=C3)S(=O)(=O)N"	"QMTFSGDBEOQNOF-UHFFFAOYSA-N"	"InChI=1S/C9H10N2O2S.6CO.2Co/c1-2-7-11-8-3-5-9(6-4-8)14(10,12)13;6*1-2;;/h1,3-6,11H,7H2,(H2,10,12,13);;;;;;;;"	"yes"	""	""
"10441"	"compound 5d [PMID: 31335136]"	""	"Synthetic organic"	""	""	""	""	"385612201"	"135197617"	""	""	""	""	""	""	""	"2,4-difluoro-N-[2-methoxy-5-[4-methyl-8-[(3-methyloxetan-3-yl)methoxy]quinazolin-6-yl]pyridin-3-yl]benzenesulfonamide"	""	"Example 59 [WO2018121550]"	"COc1ncc(cc1NS(=O)(=O)c1ccc(cc1F)F)c1cc(OCC2(C)COC2)c2c(c1)c(C)ncn2"	"CPUXOJVJEJZOSP-UHFFFAOYSA-N"	"InChI=1S/C26H24F2N4O5S/c1-15-19-6-16(8-22(24(19)31-14-30-15)37-13-26(2)11-36-12-26)17-7-21(25(35-3)29-10-17)32-38(33,34)23-5-4-18(27)9-20(23)28/h4-10,14,32H,11-13H2,1-3H3"	"yes"	""	""
"9712"	"compound 5e [PMID: 28580438]"	""	"Synthetic organic"	""	""	""	""	"348353671"	"131801163"	""	""	""	""	""	""	""	"N4-(propan-2-yl)-N2-[3-(pyridin-3-yl)phenyl]pyrimidine-2,4-diamine"	""	""	"CC(Nc1ccnc(n1)Nc1cccc(c1)c1cccnc1)C"	"JTFUPGNZUPRHCZ-UHFFFAOYSA-N"	"InChI=1S/C18H19N5/c1-13(2)21-17-8-10-20-18(23-17)22-16-7-3-5-14(11-16)15-6-4-9-19-12-15/h3-13H,1-2H3,(H2,20,21,22,23)"	"yes"	""	""
"12336"	"compound 5i [PMID: 36542759]"	""	"Synthetic organic"	""	""	""	""	"479821127"	"166642424"	""	""	""	""	""	""	""	""	""	""	"OC[C@H]1Nc2c(cnc(Nc3cc(CCCCOc4c1cccc4)c(cc3)C#N)n2)c1cn(CC(C)(O)C)nc1"	"DSSNAGYVGTYAGH-AREMUKBSSA-N"	"InChI=1S/C30H33N7O3/c1-30(2,39)19-37-17-22(15-33-37)25-16-32-29-34-23-11-10-21(14-31)20(13-23)7-5-6-12-40-27-9-4-3-8-24(27)26(18-38)35-28(25)36-29/h3-4,8-11,13,15-17,26,38-39H,5-7,12,18-19H2,1-2H3,(H2,32,34,35,36)/t26-/m1/s1"	"yes"	""	""
"13911"	"compound 669 [WO2021055376A1]"	""	"Synthetic organic"	""	""	""	""	"513757596"	"156188935"	""	""	""	""	""	""	""	""	""	""	"CCC(=O)N[C@H]([C@@H](C)C1=CC(F)=C(NC(=O)[C@@H](NC(=O)C(F)(F)C2CCOCC2)[C@H]3CC[C@H](C)CC3)C=C1)C(=O)N4CCN(C)CC4"	"JQJIKYJEWUSKJS-GVIAMBBFSA-N"	"InChI=1S/C34H50F3N5O5/c1-5-28(43)39-29(32(45)42-16-14-41(4)15-17-42)22(3)24-10-11-27(26(35)20-24)38-31(44)30(23-8-6-21(2)7-9-23)40-33(46)34(36,37)25-12-18-47-19-13-25/h10-11,20-23,25,29-30H,5-9,12-19H2,1-4H3,(H,38,44)(H,39,43)(H,40,46)/t21-,22-,23-,29+,30-/m0/s1"	"yes"	""	""
"11203"	"compound 71 [WO2018191577A1]"	""	"Synthetic organic"	""	""	""	""	"434122263"	"135355847"	""	""	""	""	""	""	""	"1-tert-butyl-N-[8-[2-[(1-methylpyrazol-4-yl)amino]pyrimidin-4-yl]-2-(oxetan-3-yl)-1,3,4,5-tetrahydro-2-benzazepin-5-yl]triazole-4-carboxamide"	""	""	"Cn1ncc(c1)Nc1nccc(n1)c1ccc2c(c1)CN(CCC2NC(=O)c1nnn(c1)C(C)(C)C)C1COC1"	"JSAQBOQCZJHWMA-UHFFFAOYSA-N"	"InChI=1S/C28H34N10O2/c1-28(2,3)38-15-25(34-35-38)26(39)32-24-8-10-37(21-16-40-17-21)13-19-11-18(5-6-22(19)24)23-7-9-29-27(33-23)31-20-12-30-36(4)14-20/h5-7,9,11-12,14-15,21,24H,8,10,13,16-17H2,1-4H3,(H,32,39)(H,29,31,33)"	"yes"	""	""
"9609"	"compound 76 [PMID: 28657314]"	""	"Synthetic organic"	""	""	""	""	"340590239"	"129320517"	""	""	""	""	""	""	""	"ethyl 3-[8-({4-methyl-5-[(3-methyl-4-oxo-3,4-dihydrophthalazin-1-yl)methyl]-4H-1,2,4-triazol-3-yl}sulfanyl)octanamido]benzoate"	""	""	"CCOC(=O)c1cccc(c1)NC(=O)CCCCCCCSc1nnc(n1C)Cc1nn(C)c(=O)c2c1cccc2"	"GWNFQAKCJYEJEW-UHFFFAOYSA-N"	"InChI=1S/C30H36N6O4S/c1-4-40-29(39)21-13-12-14-22(19-21)31-27(37)17-8-6-5-7-11-18-41-30-33-32-26(35(30)2)20-25-23-15-9-10-16-24(23)28(38)36(3)34-25/h9-10,12-16,19H,4-8,11,17-18,20H2,1-3H3,(H,31,37)"	"yes"	""	""
"9931"	"compound 7c [PMID: 22041175]"	""	"Synthetic organic"	""	""	""	""	"363894225"	"51035721"	""	""	"CHEMBL1962788"	""	""	""	""	"10-benzyl-2-(2-chlorophenyl)-7,8,9,11-tetrahydro-3H-pyrazolo[4,5]pyrido[5,6-a][1,4]diazepine-1,5-dione"	""	""	"Clc1ccccc1n1[nH]c2c(c1=O)c1CN(CCCn1c(=O)c2)Cc1ccccc1"	"DISVMXDWAMMVLT-UHFFFAOYSA-N"	"InChI=1S/C23H21ClN4O2/c24-17-9-4-5-10-19(17)28-23(30)22-18(25-28)13-21(29)27-12-6-11-26(15-20(22)27)14-16-7-2-1-3-8-16/h1-5,7-10,13,25H,6,11-12,14-15H2"	"yes"	""	""
"9937"	"compound 7d [PMID: 29672049]"	""	"Synthetic organic"	""	""	""	""	"363894231"	"133081975"	""	""	""	""	""	""	""	"9-cyclopentyl-N6-[4-(morpholin-4-ylmethyl)phenyl]-N2-[(1r,4r)-4-aminocyclohexyl]-9H-purine-2,6-diamine"	""	""	"N[C@@H]1CC[C@H](CC1)Nc1nc(Nc2ccc(cc2)CN2CCOCC2)c2c(n1)n(cn2)C1CCCC1"	"SAEGVASGMTZGFI-AQYVVDRMSA-N"	"InChI=1S/C27H38N8O/c28-20-7-11-22(12-8-20)31-27-32-25(24-26(33-27)35(18-29-24)23-3-1-2-4-23)30-21-9-5-19(6-10-21)17-34-13-15-36-16-14-34/h5-6,9-10,18,20,22-23H,1-4,7-8,11-17,28H2,(H2,30,31,32,33)/t20-,22-"	"yes"	""	""
"9794"	"compound 7f [PMID: 29191554]"	""	"Synthetic organic"	""	""	""	""	"354702266"	"86672192"	""	""	""	""	""	""	""	"2-amino-4-[(1R)-1-{[(3Z,6R)-6-[(5-chloro-2-methoxyphenyl)methyl]-7-oxo-3-(phenoxyimino)-1,4-diazepane-1-carbonyl]amino}propyl]benzoic acid"	""	"example 32 [WO2011078413]"	"CC[C@H](c1ccc(c(c1)N)C(=O)O)NC(=O)N1C/C(=N/Oc2ccccc2)/NC[C@H](C1=O)Cc1cc(Cl)ccc1OC"	"LHASZEBEQGPCFM-CJFMBICVSA-N"	"InChI=1S/C30H32ClN5O6/c1-3-25(18-9-11-23(29(38)39)24(32)15-18)34-30(40)36-17-27(35-42-22-7-5-4-6-8-22)33-16-20(28(36)37)13-19-14-21(31)10-12-26(19)41-2/h4-12,14-15,20,25H,3,13,16-17,32H2,1-2H3,(H,33,35)(H,34,40)(H,38,39)/t20-,25-/m1/s1"	"yes"	""	""
"9780"	"compound 7f [PMID: 29283260]"	""	"Synthetic organic"	""	""	""	""	"354702253"	"118165440"	""	""	""	""	""	""	""	"1-(3-amino-1H-1,2,4-triazol-5-yl)-N-[2-(4-chlorophenyl)ethyl]-N-(2-methylpropyl)piperidin-4-amine"	""	""	"CC(CN(C1CCN(CC1)c1[nH]nc(n1)N)CCc1ccc(cc1)Cl)C"	"BADSWYIEDNZIEB-UHFFFAOYSA-N"	"InChI=1S/C19H29ClN6/c1-14(2)13-26(10-7-15-3-5-16(20)6-4-15)17-8-11-25(12-9-17)19-22-18(21)23-24-19/h3-6,14,17H,7-13H2,1-2H3,(H3,21,22,23,24)"	"yes"	""	""
"10450"	"compound 7 [PMID: 31381331]"	""	"Synthetic organic"	""	""	""	""	"385612210"	"139030528"	""	""	""	""	""	""	""	"(3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S,3R)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate"	""	""	"[O-]C(=O)C[C@@H](c1cccc(c1)n1nc(cc1C)C)C[N@@+]1(C)CC[C@H](C1)CCc1ccc2c(n1)NCCC2"	"BXOSGYRJKCYDLH-YAYCEGLDSA-N"	"InChI=1S/C30H39N5O2/c1-21-16-22(2)34(33-21)28-8-4-6-25(17-28)26(18-29(36)37)20-35(3)15-13-23(19-35)9-11-27-12-10-24-7-5-14-31-30(24)32-27/h4,6,8,10,12,16-17,23,26H,5,7,9,11,13-15,18-20H2,1-3H3,(H-,31,32,36,37)/t23-,26-,35+/m1/s1"	"yes"	""	""
"8085"	"compound 7 [WO2012007375]"	""	"Synthetic organic"	""	""	""	""	"249565765"	"58056092"	""	""	""	""	""	""	""	"2-[(2-aminoethyl)(methyl)amino]-N-(7-methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide"	""	""	"NCCN(c1ncc2c(n1)c(cs2)C(=O)Nc1cc2cccnc2cc1OC)C"	"BUJSZRICYLPWCM-UHFFFAOYSA-N"	"InChI=1S/C20H20N6O2S/c1-26(7-5-21)20-23-10-17-18(25-20)13(11-29-17)19(27)24-15-8-12-4-3-6-22-14(12)9-16(15)28-2/h3-4,6,8-11H,5,7,21H2,1-2H3,(H,24,27)"	"yes"	""	""
"14506"	"compound 7 [WO2020160054]"	""	"Synthetic organic"	""	""	""	""	""	"154666617"	""	""	""	""	""	""	""	"3-[4-(4-amino-2-butylimidazo[4,5-c]quinolin-1-yl)oxybutyl-[3-(dimethylamino)propyl]amino]-4-(heptadecylamino)cyclobut-3-ene-1,2-dione"	""	""	"CCCCCCCCCCCCCCCCCNC1=C(C(=O)C1=O)N(CCCCON2C(=NC3=C2C4=CC=CC=C4N=C3N)CCCC)CCCN(C)C"	"QCDHMRIADDJSDR-UHFFFAOYSA-N"	"InChI=1S/C44H71N7O3/c1-5-7-9-10-11-12-13-14-15-16-17-18-19-20-23-30-46-38-41(43(53)42(38)52)50(33-26-31-49(3)4)32-24-25-34-54-51-37(29-8-6-2)48-39-40(51)35-27-21-22-28-36(35)47-44(39)45/h21-22,27-28,46H,5-20,23-26,29-34H2,1-4H3,(H2,45,47)"	"yes"	""	""
"8856"	"compound 8a [PMID: 23713581]"	""	"Synthetic organic"	""	""	""	""	"252827513"	"71734765"	""	""	"CHEMBL2396718"	""	""	""	""	"3-[2-(3-chlorophenyl)ethynyl]-6-hydroxy-2-[4-[2-oxo-2-(propylamino)ethoxy]phenyl]-1-benzofuran-5-carboxylic acid"	""	""	"CCCNC(=O)COc1ccc(cc1)c1oc2c(c1C#Cc1cccc(c1)Cl)cc(c(c2)O)C(=O)O"	"ZAKVHDWXAFAMTH-UHFFFAOYSA-N"	"InChI=1S/C28H22ClNO6/c1-2-12-30-26(32)16-35-20-9-7-18(8-10-20)27-21(11-6-17-4-3-5-19(29)13-17)22-14-23(28(33)34)24(31)15-25(22)36-27/h3-5,7-10,13-15,31H,2,12,16H2,1H3,(H,30,32)(H,33,34)"	"yes"	""	""
"9671"	"compound 8c [PMID: 28760529]"	""	"Synthetic organic"	""	""	""	""	"348353630"	"131801156"	""	""	""	""	""	""	""	"6-{[2-chloro-4-nitro-5-(oxan-4-yloxy)phenyl]amino}-3,4-dihydro-1H-quinolin-2-one"	""	""	"O=C1CCc2c(N1)ccc(c2)Nc1cc(OC2CCOCC2)c(cc1Cl)[N+](=O)[O-]"	"RRELDGDKULRRDM-UHFFFAOYSA-N"	"InChI=1S/C20H20ClN3O5/c21-15-10-18(24(26)27)19(29-14-5-7-28-8-6-14)11-17(15)22-13-2-3-16-12(9-13)1-4-20(25)23-16/h2-3,9-11,14,22H,1,4-8H2,(H,23,25)"	"yes"	""	""
"9478"	"compound 8ic [PMID: 19081254]"	""	"Synthetic organic"	""	""	""	""	"329968418"	"25141190"	""	""	"CHEMBL508207"	""	""	""	""	"N-cycloheptyl-6,7-dimethoxy-2-(4-piperidin-1-ylpiperidin-1-yl)quinazolin-4-amine"	""	"CCR4 Antagonist"	"COc1cc2c(NC3CCCCCC3)nc(nc2cc1OC)N1CCC(CC1)N1CCCCC1"	"WYVBISCFCHREDA-UHFFFAOYSA-N"	"InChI=1S/C27H41N5O2/c1-33-24-18-22-23(19-25(24)34-2)29-27(30-26(22)28-20-10-6-3-4-7-11-20)32-16-12-21(13-17-32)31-14-8-5-9-15-31/h18-21H,3-17H2,1-2H3,(H,28,29,30)"	"yes"	""	""
"10498"	"compound 8 [PMID: 25898023]"	""	"Synthetic organic"	""	""	""	""	"387065580"	"71283262"	""	""	"CHEMBL3426624"	""	""	""	""	"methyl 4-[[3-[2-(aminomethyl)-5-[(3-fluoropyridin-4-yl)carbamoyl]phenyl]benzoyl]amino]benzoate"	""	""	"NCc1ccc(cc1c1cccc(c1)C(=O)Nc1ccc(cc1)C(=O)OC)C(=O)Nc1ccncc1F"	"MXWDBTLNBKIMEX-UHFFFAOYSA-N"	"InChI=1S/C28H23FN4O4/c1-37-28(36)17-7-9-22(10-8-17)32-26(34)19-4-2-3-18(13-19)23-14-20(5-6-21(23)15-30)27(35)33-25-11-12-31-16-24(25)29/h2-14,16H,15,30H2,1H3,(H,32,34)(H,31,33,35)"	"yes"	""	""
"10682"	"compound 8u [PMID: 31999451]"	""	"Synthetic organic"	""	""	""	""	"404859129"	"145996539"	""	""	""	""	""	""	""	"(Z)-N-(3,5-Dimethoxyphenyl)-2-((4-(hydroxyimino)-1-oxo-1,4-dihydronaphthalen-2-yl) amino)-3-phenylpropanamide"	""	""	"O/N=C/1\C=C(NC(C(=O)Nc2cc(OC)cc(c2)OC)Cc2ccccc2)C(=O)c2c1cccc2"	"BTNMSAUAXSTYIU-JJKYIXSRSA-N"	"InChI=1S/C27H25N3O5/c1-34-19-13-18(14-20(15-19)35-2)28-27(32)25(12-17-8-4-3-5-9-17)29-24-16-23(30-33)21-10-6-7-11-22(21)26(24)31/h3-11,13-16,25,29,33H,12H2,1-2H3,(H,28,32)/b30-23+"	"yes"	""	""
"10083"	"Compound 9  [doi:10.26434/chemrxiv.7072592.v1]"	""	"Synthetic organic"	""	""	""	""	"375973270"	"134813914"	""	""	""	""	""	""	""	""	""	""	"C=CC(=O)NCCOc1ccc(cc1)c1[nH]c2c(C#N)cnn2c(=O)c1C(C)C"	"GAWCCMHWAMQURK-UHFFFAOYSA-N"	"InChI=1S/C21H21N5O3/c1-4-17(27)23-9-10-29-16-7-5-14(6-8-16)19-18(13(2)3)21(28)26-20(25-19)15(11-22)12-24-26/h4-8,12-13,25H,1,9-10H2,2-3H3,(H,23,27)"	"yes"	""	""
"10448"	"compound 9 [Kumar <i>et al</i>., 2019]"	""	"Synthetic organic"	""	""	""	""	"385612208"	"139030527"	""	""	""	""	""	""	""	"N-(4-Chlorophenyl)-N-(3-oxo-cyclohex-1-enyl)acetamide"	""	""	"CC(=O)N(c1ccc(cc1)Cl)C1=CC(=O)CCC1"	"UOYMKJRPIIMBTR-UHFFFAOYSA-N"	"InChI=1S/C14H14ClNO2/c1-10(17)16(12-7-5-11(15)6-8-12)13-3-2-4-14(18)9-13/h5-9H,2-4H2,1H3"	"yes"	""	""
"9761"	"compound 9 [PMID: 26006010]"	""	"Synthetic organic"	""	""	""	""	"354702234"	"73389638"	""	""	"CHEMBL3702836"	""	""	""	""	"(E)-2-[(2S)-2-[[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]pyrrolidine-1-carbonyl]-4-methyl-4-[methyl(oxetan-3-yl)amino]pent-2-enenitrile"	""	""	"N#C/C(=C\C(N(C1COC1)C)(C)C)/C(=O)N1CCC[C@H]1Cn1nc(c2c1ncnc2N)c1ccc(cc1F)Oc1ccccc1"	"YELZMARZEBVKBL-VAZXNAHHSA-N"	"InChI=1S/C33H35FN8O3/c1-33(2,40(3)23-18-44-19-23)15-21(16-35)32(43)41-13-7-8-22(41)17-42-31-28(30(36)37-20-38-31)29(39-42)26-12-11-25(14-27(26)34)45-24-9-5-4-6-10-24/h4-6,9-12,14-15,20,22-23H,7-8,13,17-19H2,1-3H3,(H2,36,37,38)/b21-15+/t22-/m0/s1"	"yes"	""	""
"12354"	"compound G1 [PMID: 36689364]"	""	"Synthetic organic"	""	""	""	""	"479821145"	"167993638"	""	""	""	""	""	""	""	"1-((1r,3R,5S,7r)-3,5-Dimethyladamantan-1-yl)-3-(2-fluoro-4-((3-(4-propionyl-1,4-diazepane-1-carbonyl)piperidin-1-yl)methyl)phenyl)urea"	""	""	"O=C(Nc1ccc(CN2CCCC(C(=O)N3CCCN(C(=O)CC)CC3)C2)cc1F)N[C@]12C[C@H]3C[C@@](C[C@](C1)(C)C3)(C)C2"	"DMRRTPHESRMGJC-COLOTUKFSA-N"	"InChI=1S/C34H50FN5O3/c1-4-29(41)39-11-6-12-40(14-13-39)30(42)26-7-5-10-38(20-26)19-24-8-9-28(27(35)15-24)36-31(43)37-34-18-25-16-32(2,22-34)21-33(3,17-25)23-34/h8-9,15,25-26H,4-7,10-14,16-23H2,1-3H3,(H2,36,37,43)/t25-,26?,32+,33-,34-"	"yes"	""	""
"9709"	"compound III [PMID: 24045148]"	""	"Synthetic organic"	""	""	""	""	"348353668"	"67033699"	""	""	"CHEMBL3770411"	""	""	""	""	"N-cyclopentyl-1-(5,6-dimethyl-1-propan-2-ylbenzimidazol-2-yl)piperidine-4-carboxamide"	""	""	"O=C(C1CCN(CC1)c1nc2c(n1C(C)C)cc(c(c2)C)C)NC1CCCC1"	"FPPVJOTXZIRXTF-UHFFFAOYSA-N"	"InChI=1S/C23H34N4O/c1-15(2)27-21-14-17(4)16(3)13-20(21)25-23(27)26-11-9-18(10-12-26)22(28)24-19-7-5-6-8-19/h13-15,18-19H,5-12H2,1-4H3,(H,24,28)"	"yes"	""	""
"9579"	"compound II [PMID: 21329883]"	""	"Synthetic organic"	""	""	""	""	"336446965"	"126970685"	""	""	""	""	""	""	""	"N-{3,4-dimethoxy-5-[3-(4-methylpiperazin-1-yl)propoxy]phenyl}-1-(4-methoxyphenyl)-1H,3aH,7aH-pyrazolo[3,4-d]pyrimidin-6-amine"	""	""	"COc1ccc(cc1)N1N=CC2C1N=C(N=C2)Nc1cc(OC)c(c(c1)OCCCN1CCN(CC1)C)OC"	"DRSHXJFUUPIBHX-UHFFFAOYSA-N"	"InChI=1S/C28H37N7O4/c1-33-11-13-34(14-12-33)10-5-15-39-25-17-21(16-24(37-3)26(25)38-4)31-28-29-18-20-19-30-35(27(20)32-28)22-6-8-23(36-2)9-7-22/h6-9,16-20,27H,5,10-15H2,1-4H3,(H,31,32)"	"yes"	""	""
"12904"	"compound (S)-29 [PMID: 37606563]"	""	"Synthetic organic"	""	""	""	""	"485206025"	"168510451"	""	""	""	""	""	""	""	"1-[(1S)-1-[6-chloro-1-(pyridin-3-yl)-1H-indazol-3-yl]ethyl]-3-(3-fluoro-4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine"	""	""	"ClC1=CC=C2C(N(C3=CC=CN=C3)N=C2[C@H](C)N4C=5N=CN=C(N)C5C(C6=CC(F)=C(OC)C=C6)=N4)=C1"	"ZNCDEDBKQOCMSJ-AWEZNQCLSA-N"	"InChI=1S/C26H20ClFN8O/c1-14(23-18-7-6-16(27)11-20(18)36(33-23)17-4-3-9-30-12-17)35-26-22(25(29)31-13-32-26)24(34-35)15-5-8-21(37-2)19(28)10-15/h3-14H,1-2H3,(H2,29,31,32)/t14-/m0/s1"	"yes"	""	""
"10385"	"compound T.14"	""	"Synthetic organic"	""	""	""	""	"384403664"	"138393289"	""	""	""	""	""	""	""	"3-(4-chlorophenyl)-1-{3-[(1E)-2-(4-methoxyphenyl)ethenyl]phenyl}urea"	""	""	"COc1ccc(cc1)/C=C/c1cccc(c1)NC(=O)Nc1ccc(cc1)Cl"	"VGWVPSZVSVONQT-AATRIKPKSA-N"	"InChI=1S/C22H19ClN2O2/c1-27-21-13-7-16(8-14-21)5-6-17-3-2-4-20(15-17)25-22(26)24-19-11-9-18(23)10-12-19/h2-15H,1H3,(H2,24,25,26)/b6-5+"	"yes"	""	""
"13423"	"compound XVI [PMID: 38863440]"	""	"Synthetic organic"	""	""	""	""	"496703393"	"171061356"	""	""	""	""	""	""	""	"furan-2-yl-[4-(1-phenylpiperidin-4-yl)piperazin-1-yl]methanone"	""	""	"O=C(N1CCN(CC1)C2CCN(CC2)C3=CC=CC=C3)C4=CC=CO4"	"KVMLSNMTOXSTIK-UHFFFAOYSA-N"	"InChI=1S/C20H25N3O2/c24-20(19-7-4-16-25-19)23-14-12-22(13-15-23)18-8-10-21(11-9-18)17-5-2-1-3-6-17/h1-7,16,18H,8-15H2"	"yes"	""	""
"9218"	"compstatin"	""	"Peptide"	""	""	""	""	"315661294"	"25082538"	""	""	"CHEMBL266963"	""	""	""	""	"2-[(4R,7S,10S,13S,19S,22S,25S,28S,31S,34R)-4-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]carbamoyl]-34-[[(2S,3S)-2-amino-3-methylpentanoyl]amino]-25-(3-amino-3-oxopropyl)-7-[3-(diaminomethylideneamino)propyl]-10,13-bis(1H-imidazol-5-ylmethyl)-19-(1H-indol-3-ylmethyl)-6,9,12,15,18,21,24,27,30,33-decaoxo-28,31-di(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32-decazacyclopentatriacont-22-yl]acetic acid"	""	""	"CC[C@@H]([C@@H](C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2[nH]cnc2)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)C(C)C)CCC(=O)N)CC(=O)O)Cc1c[nH]c2c1cccc2)Cc1[nH]cnc1)C(=O)N[C@H](C(=O)N)[C@H](O)C)N)C"	"RDTRHBCZFDCUPW-KWICJJCGSA-N"	"InChI=1S/C66H99N23O17S2/c1-8-32(6)50(68)63(104)86-46-27-108-107-26-45(62(103)89-53(33(7)90)54(69)95)85-56(97)39(14-11-17-74-66(70)71)80-59(100)43(20-36-24-73-29-78-36)83-58(99)42(19-35-23-72-28-77-35)79-48(92)25-76-55(96)41(18-34-22-75-38-13-10-9-12-37(34)38)82-60(101)44(21-49(93)94)84-57(98)40(15-16-47(67)91)81-64(105)51(30(2)3)88-65(106)52(31(4)5)87-61(46)102/h9-10,12-13,22-24,28-33,39-46,50-53,75,90H,8,11,14-21,25-27,68H2,1-7H3,(H2,67,91)(H2,69,95)(H,72,77)(H,73,78)(H,76,96)(H,79,92)(H,80,100)(H,81,105)(H,82,101)(H,83,99)(H,84,98)(H,85,97)(H,86,104)(H,87,102)(H,88,106)(H,89,103)(H,93,94)(H4,70,71,74)/t32-,33+,39-,40-,41-,42-,43-,44-,45-,46-,50-,51-,52-,53-/m0/s1"	"yes"	""	""
"9535"	"CORM-2"	""	"Synthetic organic"	""	""	""	""	"336446921"	"10951331"	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"2869"	"corticosterone"	""	"Metabolite"	""	""	""	""	"135651462"	"5753"	""	""	"CHEMBL110739"	""	""	""	""	"(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one"	""	""	"OCC(=O)[C@H]1CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C"	"OMFXVFTZEKFJBZ-HJTSIMOOSA-N"	"InChI=1S/C21H30O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h9,14-17,19,22,24H,3-8,10-11H2,1-2H3/t14-,15-,16+,17-,19+,20-,21-/m0/s1"	"yes"	""	""
"6967"	"corticotropin zinc hydroxide"	""	"Peptide"	"yes"	""	""	""	"178103547"	"44362115"	""	""	"CHEMBL1201609"	""	""	""	""	""	"corticotropin zinc hydroxide"	""	"NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H]([C@H](CC)C)C(=O)O)[C@H](CC)C)CCC(=O)O)CCSC)CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CO)N)CCC(=O)O)CCC(=O)O)CO)CC(C)C)CC(=O)O)CC(C)C)Cc1ccccc1)Cc1nc[nH]c1)CC(C)C)CC(C)C)CCCN=C(N)N)CCC(=O)O)CC(C)C)CCC(=O)O)CCSC)C)CCCN=C(N)N)C)CCC(=O)O)CCC(=O)N)CC(C)C)C)CCC(=O)N)CCC(=O)N)C)Cc1nc[nH]c1)CO)CC(=O)N)CCCN=C(N)N"	"PNMZQWKBJIQQJL-FAUHKOHMSA-N"	"InChI=1S/C208H343N59O64S2/c1-30-106(20)161(263-198(323)147-49-41-75-266(147)204(329)148-50-42-76-267(148)203(328)132(59-68-158(286)287)246-179(304)126(55-64-154(278)279)235-169(294)117(210)93-268)200(325)260-146(95-270)197(322)253-137(83-102(12)13)189(314)256-144(90-159(288)289)194(319)252-139(85-104(16)17)195(320)265-164(113(27)271)202(327)258-140(86-114-43-34-33-35-44-114)190(315)254-142(88-116-92-222-97-227-116)191(316)251-136(82-101(10)11)188(313)250-135(81-100(8)9)185(310)237-121(48-40-74-225-208(219)220)174(299)241-128(57-66-156(282)283)182(307)261-160(105(18)19)199(324)257-138(84-103(14)15)187(312)243-127(56-65-155(280)281)178(303)244-130(69-77-332-28)172(297)230-109(23)165(290)232-119(46-38-72-223-206(215)216)170(295)228-110(24)166(291)234-125(54-63-153(276)277)177(302)240-124(53-62-151(213)274)180(305)248-133(79-98(4)5)184(309)231-111(25)167(292)233-123(52-61-150(212)273)176(301)239-122(51-60-149(211)272)171(296)229-112(26)168(293)247-141(87-115-91-221-96-226-115)192(317)259-145(94-269)196(321)255-143(89-152(214)275)193(318)238-120(47-39-73-224-207(217)218)173(298)236-118(45-36-37-71-209)175(300)249-134(80-99(6)7)186(311)245-131(70-78-333-29)181(306)242-129(58-67-157(284)285)183(308)262-162(107(21)31-2)201(326)264-163(205(330)331)108(22)32-3/h33-35,43-44,91-92,96-113,117-148,160-164,268-271H,30-32,36-42,45-90,93-95,209-210H2,1-29H3,(H2,211,272)(H2,212,273)(H2,213,274)(H2,214,275)(H,221,226)(H,222,227)(H,228,295)(H,229,296)(H,230,297)(H,231,309)(H,232,290)(H,233,292)(H,234,291)(H,235,294)(H,236,298)(H,237,310)(H,238,318)(H,239,301)(H,240,302)(H,241,299)(H,242,306)(H,243,312)(H,244,303)(H,245,311)(H,246,304)(H,247,293)(H,248,305)(H,249,300)(H,250,313)(H,251,316)(H,252,319)(H,253,322)(H,254,315)(H,255,321)(H,256,314)(H,257,324)(H,258,327)(H,259,317)(H,260,325)(H,261,307)(H,262,308)(H,263,323)(H,264,326)(H,265,320)(H,276,277)(H,278,279)(H,280,281)(H,282,283)(H,284,285)(H,286,287)(H,288,289)(H,330,331)(H4,215,216,223)(H4,217,218,224)(H4,219,220,225)/t106-,107-,108-,109-,110-,111-,112-,113+,117-,118-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,160-,161-,162-,163-,164-/m0/s1"	"yes"	""	""
"2868"	"cortisol"	""	"Metabolite"	"yes"	""	""	""	"53801089"	"5754"	""	""	"CHEMBL389621"	""	""	""	""	"(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one"	"hydrocortisone"	"Acticort&reg;|Efmody&reg;|Plenadren&reg;"	"OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C"	"JYGXADMDTFJGBT-VWUMJDOOSA-N"	"InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1"	"yes"	""	""
"10469"	"COVA322"	""	"Antibody"	""	""	""	""	"385612229"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"3368"	"CP105696"	""	"Synthetic organic"	""	""	""	""	"178100392"	"9867257"	""	""	"CHEMBL51770"	""	""	""	""	"1-[(3S,4R)-4-hydroxy-3-[(4-phenylphenyl)methyl]chroman-7-yl]cyclopentane-1-carboxylic acid"	""	"CP 105696|CP-105,696|CP-105696"	"OC(=O)C1(CCCC1)c1ccc2c(c1)OC[C@@H]([C@H]2O)Cc1ccc(cc1)c1ccccc1"	"KMNLXCBYBKHKSK-BKMJKUGQSA-N"	"InChI=1S/C28H28O4/c29-26-22(16-19-8-10-21(11-9-19)20-6-2-1-3-7-20)18-32-25-17-23(12-13-24(25)26)28(27(30)31)14-4-5-15-28/h1-3,6-13,17,22,26,29H,4-5,14-16,18H2,(H,30,31)/t22-,26+/m0/s1"	"yes"	""	""
"6155"	"CP-195543"	""	"Synthetic organic"	""	""	""	""	"178102776"	"9823886"	""	""	"CHEMBL301829"	""	""	""	""	"2-[(3S,4R)-4-hydroxy-3-(phenylmethyl)chroman-7-yl]-4-(trifluoromethyl)benzoic acid"	""	"CP 195543|CP-195,543|CP195543"	"O[C@@H]1[C@H](COc2c1ccc(c2)c1cc(ccc1C(=O)O)C(F)(F)F)Cc1ccccc1"	"NZQDWKCNBOELAI-KSFYIVLOSA-N"	"InChI=1S/C24H19F3O4/c25-24(26,27)17-7-9-18(23(29)30)20(12-17)15-6-8-19-21(11-15)31-13-16(22(19)28)10-14-4-2-1-3-5-14/h1-9,11-12,16,22,28H,10,13H2,(H,29,30)/t16-,22+/m0/s1"	"yes"	""	""
"14284"	"CP-25"	""	"Synthetic organic"	""	""	""	""	"521588924"	"173640849"	""	""	""	""	""	""	""	""	""	"Paeoniflorin-6′-O-benzene sulfonate"	"O=C(C1=CC=CC=C1)OC[C@@]23[C@]4([C@]5(O[C@]2([H])O[C@@]([C@]3([H])C4)(C5)O)C)O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)COS(=O)(C7=CC=CC=C7)=O"	"GWADTSPXFRXHLU-DMXKJYKPSA-N"	"InChI=1S/C29H32O13S/c1-26-14-28(34)19-12-29(26,27(19,25(41-26)42-28)15-37-23(33)16-8-4-2-5-9-16)40-24-22(32)21(31)20(30)18(39-24)13-38-43(35,36)17-10-6-3-7-11-17/h2-11,18-22,24-25,30-32,34H,12-15H2,1H3/t18-,19-,20-,21+,22-,24+,25-,26+,27+,28-,29+/m1/s1"	"yes"	""	""
"11809"	"CP-412,245"	""	"Synthetic organic"	""	""	""	""	"458923844"	"162366979"	""	""	""	""	""	""	""	"3-[4-chloro-2,6-bis(propan-2-yl)phenyl]-1-[3-(propan-2-yl)benzenesulfonyl]urea"	""	""	"CC(C)c1cc(ccc1)S(=O)(=O)NC(=O)Nc1c(cc(Cl)cc1C(C)C)C(C)C"	"ZKEBNWAADHAYQJ-UHFFFAOYSA-N"	"InChI=1S/C22H29ClN2O3S/c1-13(2)16-8-7-9-18(10-16)29(27,28)25-22(26)24-21-19(14(3)4)11-17(23)12-20(21)15(5)6/h7-15H,1-6H3,(H2,24,25,26)"	"yes"	""	""
"11810"	"CP-424,174"	""	"Synthetic organic"	""	""	""	""	"458923845"	"9911728"	""	""	"CHEMBL3781583"	""	""	""	""	"3-[4-chloro-2,6-bis(propan-2-yl)phenyl]-1-[3-(2-hydroxypropan-2-yl)benzenesulfonyl]urea"	""	"CP-424174"	"CC(C)c1cc(Cl)cc(C(C)C)c1NC(=O)NS(=O)(=O)c1cccc(c1)C(C)(C)O"	"YRSBLSHMKVQWHP-UHFFFAOYSA-N"	"InChI=1S/C22H29ClN2O4S/c1-13(2)18-11-16(23)12-19(14(3)4)20(18)24-21(26)25-30(28,29)17-9-7-8-15(10-17)22(5,6)27/h7-14,27H,1-6H3,(H2,24,25,26)"	"yes"	""	""
"11317"	"CpdA (parent molecule)"	""	"Synthetic organic"	""	""	""	""	"434321752"	"9838148"	""	""	""	""	""	""	""	"[4-[1-chloro-2-(methylamino)ethyl]phenyl] acetate"	""	""	"CNCC(c1ccc(cc1)OC(=O)C)Cl"	"VZCQEZNQVVYTJC-UHFFFAOYSA-N"	"InChI=1S/C11H14ClNO2/c1-8(14)15-10-5-3-9(4-6-10)11(12)7-13-2/h3-6,11,13H,7H2,1-2H3"	"yes"	""	""
"9710"	"CPUY192018"	""	"Synthetic organic"	""	""	""	""	"348353669"	"73330369"	""	""	""	""	""	""	""	"2-[[4-[carboxymethyl-(4-methoxyphenyl)sulfonylamino]naphthalen-1-yl]-(4-methoxyphenyl)sulfonylamino]acetic acid"	""	"compound 18e [PMID: 26258437]|compound 2 [PMID: 24512214]"	"COc1ccc(cc1)S(=O)(=O)N(c1ccc(c2c1cccc2)N(S(=O)(=O)c1ccc(cc1)OC)CC(=O)O)CC(=O)O"	"KWSIQJUNYMMCTB-UHFFFAOYSA-N"	"InChI=1S/C28H26N2O10S2/c1-39-19-7-11-21(12-8-19)41(35,36)29(17-27(31)32)25-15-16-26(24-6-4-3-5-23(24)25)30(18-28(33)34)42(37,38)22-13-9-20(40-2)10-14-22/h3-16H,17-18H2,1-2H3,(H,31,32)(H,33,34)"	"yes"	""	""
"9845"	"CR6086"	""	"Synthetic organic"	""	""	""	""	"363894139"	"133081958"	""	""	""	""	""	""	""	"4-{1-[(5R)-6-{[4-(trifluoromethyl)phenyl]methyl}-6-azaspiro[2.5]octane-5-amido]cyclopropyl}benzoic acid"	""	""	"O=C([C@H]1CC2(CCN1Cc1ccc(cc1)C(F)(F)F)CC2)NC1(CC1)c1ccc(cc1)C(=O)O"	"CADWTPLFEZSAHM-OAQYLSRUSA-N"	"InChI=1S/C26H27F3N2O3/c27-26(28,29)20-5-1-17(2-6-20)16-31-14-13-24(9-10-24)15-21(31)22(32)30-25(11-12-25)19-7-3-18(4-8-19)23(33)34/h1-8,21H,9-16H2,(H,30,32)(H,33,34)/t21-/m1/s1"	"yes"	""	""
"10041"	"CRAC channel inhibitor 1 [PMID: 26256403]"	""	"Synthetic organic"	""	""	""	""	"375973229"	"3509452"	""	""	"CHEMBL3923438"	""	""	""	""	"3-(4-chlorophenyl)-1-[1-(4-methylphenyl)propyl]urea"	""	""	"CCC(c1ccc(cc1)C)NC(=O)Nc1ccc(cc1)Cl"	"FKBYZUDELOWDJW-UHFFFAOYSA-N"	"InChI=1S/C17H19ClN2O/c1-3-16(13-6-4-12(2)5-7-13)20-17(21)19-15-10-8-14(18)9-11-15/h4-11,16H,3H2,1-2H3,(H2,19,20,21)"	"yes"	""	""
"10042"	"CRAC channel inhibitor 5b [PMID: 26256403]"	""	"Synthetic organic"	""	""	""	""	"375973230"	"134813903"	""	""	""	""	""	""	""	"1-(4-chlorophenyl)-1,3-dimethyl-3-[1-(4-methylphenyl)propyl]urea"	""	""	"CCC(N(C(=O)N(c1ccc(cc1)Cl)C)C)c1ccc(cc1)C"	"YPDVKFTYHRFBSZ-UHFFFAOYSA-N"	"InChI=1S/C19H23ClN2O/c1-5-18(15-8-6-14(2)7-9-15)22(4)19(23)21(3)17-12-10-16(20)11-13-17/h6-13,18H,5H2,1-4H3"	"yes"	""	""
"6266"	"CRAMP"	"Mouse"	"Peptide"	""	""	""	""	"178102886"	"155817495"	"P51437"	"ENSMUSG00000038357"	""	""	""	""	""	""	""	""	"CC[C@H](C)[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)O)C(=O)O)C(C)C)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC"	"QBSFTGGUOCPHDM-GDCSACRRSA-N"	"InChI=1S/C197H338N56O50/c1-22-112(17)158(210)189(296)247-143(105-254)186(293)235-128(65-49-89-216-197(213)214)170(277)240-136(93-107(7)8)178(285)222-116(21)163(270)218-102-154(263)226-135(92-106(5)6)179(286)243-138(95-109(11)12)181(288)234-127(64-48-88-215-196(211)212)166(273)227-119(56-32-40-80-198)164(271)219-100-150(259)217-101-151(260)224-130(71-77-155(264)265)173(280)232-125(62-38-46-86-204)176(283)250-161(114(19)24-3)191(298)221-104-153(262)225-131(72-78-156(266)267)172(279)228-121(58-34-42-82-200)167(274)241-137(94-108(9)10)180(287)233-120(57-33-41-81-199)165(272)230-124(61-37-45-85-203)175(282)249-160(113(18)23-2)190(297)220-103-152(261)223-129(68-74-146(206)255)171(278)231-126(63-39-47-87-205)177(284)251-162(115(20)25-4)192(299)237-123(60-36-44-84-202)169(276)246-142(99-149(209)258)184(291)245-141(98-118-54-30-27-31-55-118)183(290)244-140(97-117-52-28-26-29-53-117)182(289)236-132(69-75-147(207)256)174(281)229-122(59-35-43-83-201)168(275)242-139(96-110(13)14)185(292)248-159(111(15)16)194(301)253-91-51-67-145(253)187(294)238-133(70-76-148(208)257)193(300)252-90-50-66-144(252)188(295)239-134(195(302)303)73-79-157(268)269/h26-31,52-55,106-116,119-145,158-162,254H,22-25,32-51,56-105,198-205,210H2,1-21H3,(H2,206,255)(H2,207,256)(H2,208,257)(H2,209,258)(H,217,259)(H,218,270)(H,219,271)(H,220,297)(H,221,298)(H,222,285)(H,223,261)(H,224,260)(H,225,262)(H,226,263)(H,227,273)(H,228,279)(H,229,281)(H,230,272)(H,231,278)(H,232,280)(H,233,287)(H,234,288)(H,235,293)(H,236,289)(H,237,299)(H,238,294)(H,239,295)(H,240,277)(H,241,274)(H,242,275)(H,243,286)(H,244,290)(H,245,291)(H,246,276)(H,247,296)(H,248,292)(H,249,282)(H,250,283)(H,251,284)(H,264,265)(H,266,267)(H,268,269)(H,302,303)(H4,211,212,215)(H4,213,214,216)/t112-,113-,114-,115-,116-,119-,120-,121-,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,158-,159-,160-,161-,162-/m0/s1"	"yes"	""	""
"7882"	"crenolanib"	""	"Synthetic organic"	""	""	""	""	"223366211"	"10366136"	""	""	"CHEMBL2105728"	""	""	""	""	"1-[2-[5-[(3-methyloxetan-3-yl)methoxy]benzimidazol-1-yl]quinolin-8-yl]piperidin-4-amine"	"crenolanib"	"ARO-002|CP 868596|CP-868,596|CP-868596"	"NC1CCN(CC1)c1cccc2c1nc(cc2)n1cnc2c1ccc(c2)OCC1(C)COC1"	"DYNHJHQFHQTFTP-UHFFFAOYSA-N"	"InChI=1S/C26H29N5O2/c1-26(14-32-15-26)16-33-20-6-7-22-21(13-20)28-17-31(22)24-8-5-18-3-2-4-23(25(18)29-24)30-11-9-19(27)10-12-30/h2-8,13,17,19H,9-12,14-16,27H2,1H3"	"yes"	""	""
"9151"	"crisaborole"	""	"Synthetic organic"	"yes"	""	""	""	"315661236"	"44591583"	""	""	"CHEMBL484785"	""	""	""	""	"4-[(1-hydroxy-3H-2,1-benzoxaborol-5-yl)oxy]benzonitrile"	"crisaborole"	"AN 2728|AN2728|compound 5b [PMID: 19303290]|Eucrisa&reg;|Staquis&reg;"	"N#Cc1ccc(cc1)Oc1ccc2c(c1)COB2O"	"USZAGAREISWJDP-UHFFFAOYSA-N"	"InChI=1S/C14H10BNO3/c16-8-10-1-3-12(4-2-10)19-13-5-6-14-11(7-13)9-18-15(14)17/h1-7,17H,9H2"	"yes"	""	""
"4903"	"crizotinib"	""	"Synthetic organic"	"yes"	""	""	""	"178101602"	"11626560"	""	""	"CHEMBL601719"	""	""	""	""	"3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-amine"	"crizotinib"	"(<i>R</i>)-crizotinib|PF 2341066|PF-02341066|PF-2341066|PF2341066|Xalkori&reg;"	"Nc1ncc(cc1O[C@@H](c1c(Cl)ccc(c1Cl)F)C)c1cnn(c1)C1CCNCC1"	"KTEIFNKAUNYNJU-GFCCVEGCSA-N"	"InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1"	"yes"	""	""
"7608"	"cromoglicic acid"	""	"Synthetic organic"	"yes"	""	""	""	"223365943"	"2882"	""	""	"CHEMBL428880"	""	""	""	""	"5-[3-(2-carboxy-4-oxochromen-5-yl)oxy-2-hydroxypropoxy]-4-oxochromene-2-carboxylic acid"	"cromoglicic acid"	"cromoglycate|cromolyn|cromolyn sodium|FPL-670|Intal&reg;|Opticrom&reg;|sodium cromoglicate"	"OC(COc1cccc2c1c(=O)cc(o2)C(=O)O)COc1cccc2c1c(=O)cc(o2)C(=O)O"	"IMZMKUWMOSJXDT-UHFFFAOYSA-N"	"InChI=1S/C23H16O11/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30)"	"yes"	""	""
"12790"	"crovalimab"	""	"Antibody"	"yes"	""	""	""	"483123338"	""	""	""	""	""	""	""	""	""	"crovalimab"	"crovalimab-akkz|Piasky&reg;|RG-6107|RG6107|Senkai&reg; (China)|SKY59"	""	""	""	"yes"	""	""
"10091"	"CRX-555"	""	"Synthetic organic"	""	""	""	""	"381118801"	"87596969"	""	""	""	""	""	""	""	"(2S)-3-[(2R,3R,4R,5S,6R)-6-(hydroxymethyl)-3-[[(3R)-3-octanoyloxytetradecanoyl]amino]-4-[(3R)-3-octanoyloxytetradecanoyl]oxy-5-phosphonooxyoxan-2-yl]oxy-2-[[(3R)-3-octanoyloxytetradecanoyl]amino]propanoic acid"	""	"CRX555|N-[(3R)-3-(Octanoyloxy)myristoyl]-O-[2-[[(3R)-3-(octanoyloxy)myristoyl]amino]-3-O-[(3R)-3-(octanoyloxy)myristoyl]-4-O-phosphono-2-deoxy-beta-D-glucopyranosyl]-L-serine"	"CCCCCCCCCCC[C@H](CC(=O)N[C@H]1[C@H](OC[C@@H](C(=O)O)NC(=O)C[C@H](OC(=O)CCCCCCC)CCCCCCCCCCC)O[C@@H]([C@H]([C@@H]1OC(=O)C[C@H](OC(=O)CCCCCCC)CCCCCCCCCCC)OP(=O)(O)O)CO)OC(=O)CCCCCCC"	"WNFNQTGQGFHQLU-NRBIUWCVSA-N"	"InChI=1S/C75H139N2O19P/c1-7-13-19-25-28-31-34-40-43-49-60(91-67(81)52-46-37-22-16-10-4)55-65(79)76-63(74(85)86)59-90-75-71(77-66(80)56-61(92-68(82)53-47-38-23-17-11-5)50-44-41-35-32-29-26-20-14-8-2)73(72(64(58-78)94-75)96-97(87,88)89)95-70(84)57-62(93-69(83)54-48-39-24-18-12-6)51-45-42-36-33-30-27-21-15-9-3/h60-64,71-73,75,78H,7-59H2,1-6H3,(H,76,79)(H,77,80)(H,85,86)(H2,87,88,89)/t60-,61-,62-,63+,64-,71-,72-,73-,75-/m1/s1"	"yes"	""	""
"14522"	"C-type lectin domain family 2 member D"	"Human"	"Peptide"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9795"	"CU-CPT8m"	""	"Synthetic organic"	""	""	""	""	"354702267"	"15042086"	""	""	""	""	""	""	""	"7-(3-methylphenyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide"	""	"7-(m-Tolyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide|compound 5 [PMID: 29155428]"	"Cc1cccc(c1)c1ccnc2n1ncc2C(=O)N"	"HNKGGVGQAVODNJ-UHFFFAOYSA-N"	"InChI=1S/C14H12N4O/c1-9-3-2-4-10(7-9)12-5-6-16-14-11(13(15)19)8-17-18(12)14/h2-8H,1H3,(H2,15,19)"	"yes"	""	""
"9778"	"cusatuzumab"	""	"Antibody"	""	""	""	""	"354702251"	""	""	""	""	""	""	""	""	""	"cusatuzumab"	"ARGX-110|ARGX110|clone 41D12"	""	""	""	"yes"	""	""
"13373"	"CVN293"	""	"Synthetic organic"	""	""	""	""	"496703343"	"164861551"	""	""	""	""	""	""	""	"4-[7-fluoro-1-(pyridazin-3-ylmethyl)benzimidazol-2-yl]-1,2,5-oxadiazol-3-amine"	""	"CVN-293"	"NC1=NON=C1C2=NC3=C(N2CC4=CC=CN=N4)C(F)=CC=C3"	"ONRXHVJHFORDDI-UHFFFAOYSA-N"	"InChI=1S/C14H10FN7O/c15-9-4-1-5-10-12(9)22(7-8-3-2-6-17-19-8)14(18-10)11-13(16)21-23-20-11/h1-6H,7H2,(H2,16,21)"	"yes"	""	""
"9701"	"CX549"	""	"Synthetic organic"	""	""	""	""	"348353660"	"118965258"	""	""	""	""	""	""	""	"(2S)-2-amino-5-[4-[[2-[[1-[3-[3-(cyclohexylamino)propylamino]propyl]triazol-4-yl]methylamino]quinazolin-4-yl]amino]piperidin-1-yl]-5-oxopentanoic acid"	""	"compound 63 [WO2016048861]|CX-549"	"OC(=O)[C@H](CCC(=O)N1CCC(CC1)Nc1nc(NCc2nnn(c2)CCCNCCCNC2CCCCC2)nc2c1cccc2)N"	"QOVYHDHLFPKQQG-NDEPHWFRSA-N"	"InChI=1S/C33H51N11O3/c34-28(32(46)47)12-13-30(45)43-20-14-25(15-21-43)38-31-27-10-4-5-11-29(27)39-33(40-31)37-22-26-23-44(42-41-26)19-7-17-35-16-6-18-36-24-8-2-1-3-9-24/h4-5,10-11,23-25,28,35-36H,1-3,6-9,12-22,34H2,(H,46,47)(H2,37,38,39,40)/t28-/m0/s1"	"yes"	""	""
"826"	"CXCL1"	"Rat"	"Peptide"	""	""	""	""	"135651703"	""	"P14095"	"ENSRNOG00000002802"	""	""	""	""	""	""	""	"CINC|GRO&alpha;|macrophage inflammatory protein-2"	""	""	""	"yes"	""	""
"4423"	"CXCL1"	"Mouse"	"Peptide"	""	""	""	""	"135651701"	""	"P12850"	"ENSMUSG00000029380"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"819"	"CXCL1"	"Human"	"Peptide"	""	""	""	""	"135651702"	""	"P09341"	"ENSG00000163739"	""	""	""	""	""	""	""	"GRO&alpha;|melanocyte growth-stimulatory activity|MIP-2"	""	""	""	"yes"	""	""
"4430"	"CXCL10"	"Mouse"	"Peptide"	""	""	""	""	"135651704"	""	"P17515"	"ENSMUSG00000034855"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4431"	"CXCL10"	"Rat"	"Peptide"	""	""	""	""	"135651706"	""	"P48973"	"ENSRNOG00000022256"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"835"	"CXCL10"	"Human"	"Peptide"	""	""	""	""	"135651705"	""	"P02778"	"ENSG00000169245"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"836"	"CXCL11"	"Human"	"Peptide"	""	""	""	""	"135651708"	""	"O14625"	"ENSG00000169248"	""	""	""	""	""	""	""	"IP9|ITAC"	""	""	""	"yes"	""	""
"4432"	"CXCL11"	"Mouse"	"Peptide"	""	""	""	""	"135651707"	""	"Q9JHH5"	"ENSMUSG00000060183"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4465"	"CXCL12"	"Mouse"	"Peptide"	""	""	""	""	"178101202"	""	"P40224"	"ENSMUSG00000061353"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4358"	"CXCL12&alpha;"	"Human"	"Peptide"	""	""	""	""	"135651881"	""	"P48061"	"ENSG00000107562"	""	""	""	""	""	""	""	"CXCL12 &alpha;|SDF-1&alpha;|stromal cell-derived factor-1&alpha;"	""	""	""	"yes"	""	""
"845"	"CXCL12&beta;"	"Human"	"Peptide"	""	""	""	""	"135651882"	""	"P48061"	"ENSG00000107562"	""	""	""	""	""	""	""	"SDF-1&beta;|stromal cell-derived factor-1 (SDF-1)|stromal cell-derived factor-1&beta;"	""	""	""	"yes"	""	""
"8531"	"CXCL12&delta;"	"Human"	"Peptide"	""	""	""	""	"252166733"	""	"P48061"	"ENSG00000107562"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"8532"	"CXCL12&epsilon;"	"Human"	"Peptide"	""	""	""	""	"252166734"	""	"P48061"	"ENSG00000107562"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"8530"	"CXCL12&gamma;"	"Human"	"Peptide"	""	""	""	""	"252166732"	""	"P48061"	"ENSG00000107562"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"8533"	"CXCL12&phi;"	"Human"	"Peptide"	""	""	""	""	"252166735"	""	"P48061"	"ENSG00000107562"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"3645"	"CXCL13"	"Human"	"Peptide"	""	""	""	""	"135651710"	""	"O43927"	"ENSG00000156234"	""	""	""	""	""	""	""	"BCA-1"	""	""	""	"yes"	""	""
"4466"	"CXCL13"	"Mouse"	"Peptide"	""	""	""	""	"135651709"	""	"O55038"	"ENSMUSG00000023078"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"3680"	"CXCL14"	"Human"	"Peptide"	""	""	""	""	"178100570"	""	"O95715"	"ENSG00000145824"	""	""	""	""	""	""	""	"BMAC"	""	""	""	"yes"	""	""
"3862"	"CXCL15"	"Mouse"	"Peptide"	""	""	""	""	"178100701"	""	"Q9WVL7"	"ENSMUSG00000029375"	""	""	""	""	""	""	""	"lungkine (mouse)"	""	""	""	"yes"	""	""
"855"	"CXCL16"	"Human"	"Peptide"	""	""	""	""	"135651711"	""	"Q9H2A7"	"ENSG00000161921"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4433"	"CXCL16"	"Mouse"	"Peptide"	""	""	""	""	"135651712"	""	"Q8BSU2"	"ENSMUSG00000018920"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4467"	"CXCL16"	"Rat"	"Peptide"	""	""	""	""	"135651713"	""	"Q6AXU5"	"ENSRNOG00000026647"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"6479"	"CXCL17"	"Human"	"Peptide"	""	""	""	""	"178103093"	""	"Q6UXB2"	"ENSG00000189377"	""	""	""	""	""	""	""	"C-X-C motif chemokine 17|dendritic cell and monocyte chemokine-like protein"	""	""	""	"yes"	""	""
"827"	"CXCL2"	"Human"	"Peptide"	""	""	""	""	"135651714"	""	"P19875"	"ENSG00000081041"	""	""	""	""	""	""	""	"GRO&beta;|MIP-2&alpha;"	""	""	""	"yes"	""	""
"4424"	"CXCL2"	"Mouse"	"Peptide"	""	""	""	""	"135651715"	""	"P10889"	"ENSMUSG00000058427"	""	""	""	""	""	""	""	"macrophage inflammatory protein 2 (MIP-2)"	""	""	""	"yes"	""	""
"4425"	"CXCL2"	"Rat"	"Peptide"	""	""	""	""	"135651716"	""	"P30348"	"ENSRNOG00000002792"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"828"	"CXCL3"	"Human"	"Peptide"	""	""	""	""	"135651718"	""	"P19876"	"ENSG00000163734"	""	""	""	""	""	""	""	"GRO&gamma;|MIP-2&beta;"	""	""	""	"yes"	""	""
"4426"	"CXCL3"	"Mouse"	"Peptide"	""	""	""	""	"135651717"	""	"Q6W5C0"	"ENSMUSG00000029379"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4427"	"CXCL3"	"Rat"	"Peptide"	""	""	""	""	"135651719"	""	"Q10746"	"ENSRNOG00000028043"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"3685"	"CXCL4"	"Human"	"Peptide"	""	""	""	""	"178100574"	""	"P02776"	"ENSG00000163737"	""	""	""	""	""	""	""	"platelet factor 4 (PF4)"	""	""	""	"yes"	""	""
"829"	"CXCL5"	"Human"	"Peptide"	""	""	""	""	"135651721"	""	"P42830"	"ENSG00000163735"	""	""	""	""	""	""	""	"ENA-78"	""	""	""	"yes"	""	""
"4464"	"CXCL5"	"Rat"	"Peptide"	""	""	""	""	"135651720"	""	"P97885"	"ENSRNOG00000002843"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4428"	"CXCL5"	"Mouse"	"Peptide"	""	""	""	""	"135651722"	""	"P50228"	"ENSMUSG00000029371"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"820"	"CXCL6"	"Human"	"Peptide"	""	""	""	""	"135651723"	""	"P80162"	"ENSG00000124875"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"830"	"CXCL7"	"Human"	"Peptide"	""	""	""	""	"135651724"	""	"P02775"	"ENSG00000163736"	""	""	""	""	""	""	""	"PPBP"	""	""	""	"yes"	""	""
"821"	"CXCL8"	"Human"	"Peptide"	""	""	""	""	"135651725"	""	"P10145"	"ENSG00000169429"	""	""	""	""	""	""	""	"interleukin-8"	""	""	""	"yes"	""	""
"837"	"CXCL9"	"Human"	"Peptide"	""	""	""	""	"135651727"	""	"Q07325"	"ENSG00000138755"	""	""	""	""	""	""	""	"MIG|monokine induced by gamma-interferon"	""	""	""	"yes"	""	""
"4429"	"CXCL9"	"Mouse"	"Peptide"	""	""	""	""	"135651726"	""	"P18340"	"ENSMUSG00000029417"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"10146"	"CXCR4 antagonist 22"	""	"Synthetic organic"	""	""	""	""	"381118856"	"137321154"	""	""	""	""	""	""	""	"1-([1,1′-biphenyl]-3-yl)-N-((1-(2-chlorobenzyl)piperidin-4-yl)methyl)methanamine"	""	""	"Clc1ccccc1CN1CCC(CC1)CNCc1cccc(c1)c1ccccc1"	"XBEBHNXBLIDZDS-UHFFFAOYSA-N"	"InChI=1S/C26H29ClN2/c27-26-12-5-4-10-25(26)20-29-15-13-21(14-16-29)18-28-19-22-7-6-11-24(17-22)23-8-2-1-3-9-23/h1-12,17,21,28H,13-16,18-20H2"	"yes"	""	""
"4469"	"CX<sub>3</sub>CL1"	"Rat"	"Peptide"	""	""	""	""	"135651729"	""	"O55145"	"ENSRNOG00000016326"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4468"	"CX<sub>3</sub>CL1"	"Mouse"	"Peptide"	""	""	""	""	"135651728"	""	"O35188"	"ENSMUSG00000031778"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"856"	"CX<sub>3</sub>CL1"	"Human"	"Peptide"	""	""	""	""	"135651730"	""	"P78423"	"ENSG00000006210"	""	""	""	""	""	""	""	"fractalkine|neurotactin"	""	""	""	"yes"	""	""
"10057"	"CY-09"	""	"Synthetic organic"	""	""	""	""	"375973245"	"44561595"	""	""	"CHEMBL488823"	""	""	""	""	"4-[(Z)-[4-oxo-2-sulfanylidene-3-[[3-(trifluoromethyl)phenyl]methyl]-1,3-thiazolidin-5-ylidene]methyl]benzoic acid"	""	""	"S=C1S/C(=C\c2ccc(cc2)C(=O)O)/C(=O)N1Cc1cccc(c1)C(F)(F)F"	"DJTINRHPPGAPLD-DHDCSXOGSA-N"	"InChI=1S/C19H12F3NO3S2/c20-19(21,22)14-3-1-2-12(8-14)10-23-16(24)15(28-18(23)27)9-11-4-6-13(7-5-11)17(25)26/h1-9H,10H2,(H,25,26)/b15-9-"	"yes"	""	""
"13137"	"cyclic di-GMP"	""	"Synthetic organic"	""	""	""	""	"491299919"	"135440063"	""	""	"CHEMBL1231573"	""	""	""	""	""	""	"Bis-(3'-5')-cyclic dimeric guanosine monophosphate|c-di-GMP|cGpGp|dyclic diguanylate monophosphate"	"C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)O)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C6N=C(NC7=O)N)O)OP(=O)(O1)O)O"	"PKFDLKSEZWEFGL-MHARETSRSA-N"	"InChI=1S/C20H24N10O14P2/c21-19-25-13-7(15(33)27-19)23-3-29(13)17-9(31)11-5(41-17)1-39-45(35,36)44-12-6(2-40-46(37,38)43-11)42-18(10(12)32)30-4-24-8-14(30)26-20(22)28-16(8)34/h3-6,9-12,17-18,31-32H,1-2H2,(H,35,36)(H,37,38)(H3,21,25,27,33)(H3,22,26,28,34)/t5-,6-,9-,10-,11-,12-,17-,18-/m1/s1"	"yes"	""	""
"1024"	"cyclosporin A"	""	"Peptide"	"yes"	""	""	""	"135652074"	"5284373"	""	""	"CHEMBL160"	""	""	""	""	"(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(E,1R,2R)-1-hydroxy-2-methylhex-4-enyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone"	"ciclosporin"	"ciclosporin|cyclosporine|cyclosporine A|Ikervis&reg; (opthalmic solution)|Neoral&reg;|Sandimmun&reg;|Verkazia&reg; (opthalmic solution)"	"C/C=C/C[C@H]([C@H]([C@H]1C(=O)N[C@@H](CC)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)O)C"	"PMATZTZNYRCHOR-CGLBZJNRSA-N"	"InChI=1S/C62H111N11O12/c1-25-27-28-40(15)52(75)51-56(79)65-43(26-2)58(81)67(18)33-48(74)68(19)44(29-34(3)4)55(78)66-49(38(11)12)61(84)69(20)45(30-35(5)6)54(77)63-41(16)53(76)64-42(17)57(80)70(21)46(31-36(7)8)59(82)71(22)47(32-37(9)10)60(83)72(23)50(39(13)14)62(85)73(51)24/h25,27,34-47,49-52,75H,26,28-33H2,1-24H3,(H,63,77)(H,64,76)(H,65,79)(H,66,78)/b27-25+/t40-,41+,42-,43+,44+,45+,46+,47+,49+,50+,51+,52-/m1/s1"	"yes"	""	""
"9837"	"CZ415"	""	"Synthetic organic"	""	""	""	""	"363894131"	"78107195"	""	""	""	""	""	""	""	"1-[4-[7,7-dimethyl-4-(3-methylmorpholin-4-yl)-6,6-dioxo-5H-thieno[3,4-d]pyrimidin-2-yl]phenyl]-3-ethylurea"	""	"compound 3 [PMID: 27563401]|CZ-415"	"CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CS(=O)(=O)C3(C)C)C(=N2)N4CCOCC4C"	"IZLPVLBNRGPOHA-UHFFFAOYSA-N"	"InChI=1S/C22H29N5O4S/c1-5-23-21(28)24-16-8-6-15(7-9-16)19-25-18-17(13-32(29,30)22(18,3)4)20(26-19)27-10-11-31-12-14(27)2/h6-9,14H,5,10-13H2,1-4H3,(H2,23,24,28)"	"yes"	""	""
"5940"	"D4476"	""	"Synthetic organic"	""	""	""	""	"178102563"	"6419753"	""	""	"CHEMBL410456"	""	""	""	""	"4-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl]benzamide"	""	"casein kinase I inhibitor|CK1 inhibitor|D 4476"	"NC(=O)c1ccc(cc1)c1nc(c([nH]1)c1ccccn1)c1ccc2c(c1)OCCO2"	"DPDZHVCKYBCJHW-UHFFFAOYSA-N"	"InChI=1S/C23H18N4O3/c24-22(28)14-4-6-15(7-5-14)23-26-20(21(27-23)17-3-1-2-10-25-17)16-8-9-18-19(13-16)30-12-11-29-18/h1-10,13H,11-12H2,(H2,24,28)(H,26,27)"	"yes"	""	""
"6880"	"daclizumab"	""	"Antibody"	"yes"	"yes"	""	""	"178103462"	""	""	""	""	""	""	""	""	""	"daclizumab"	"L04AC01|RO-24-7375|Ro-247375|Zenapax&reg;"	""	""	""	"yes"	""	""
"9650"	"dagrocorat"	""	"Synthetic organic"	""	""	""	""	"340590280"	"24873449"	""	""	"CHEMBL3137304"	""	""	""	""	"(4bS,7R,8aR)-4b-benzyl-7-hydroxy-N-(2-methylpyridin-3-yl)-7-(trifluoromethyl)-5,6,8,8a,9,10-hexahydrophenanthrene-2-carboxamide"	"dagrocorat"	"PF-00251802"	"O=C(c1ccc2c(c1)CC[C@H]1[C@]2(CC[C@](C1)(O)C(F)(F)F)Cc1ccccc1)Nc1cccnc1C"	"QJJBNCHSWFGXML-KEKPKEOLSA-N"	"InChI=1S/C29H29F3N2O2/c1-19-25(8-5-15-33-19)34-26(35)22-10-12-24-21(16-22)9-11-23-18-28(36,29(30,31)32)14-13-27(23,24)17-20-6-3-2-4-7-20/h2-8,10,12,15-16,23,36H,9,11,13-14,17-18H2,1H3,(H,34,35)/t23-,27+,28-/m1/s1"	"yes"	""	""
"8500"	"danirixin"	""	"Synthetic organic"	""	""	""	""	"252166708"	"24780598"	""	""	"CHEMBL3039531"	""	""	""	""	"1-[4-chloro-2-hydroxy-3-[(3S)-piperidin-3-yl]sulfonylphenyl]-3-(3-fluoro-2-methylphenyl)urea"	"danirixin"	"GSK-1325756B|GSK1325756|GSK1325756B"	"O=C(Nc1cccc(c1C)F)Nc1ccc(c(c1O)S(=O)(=O)[C@H]1CCCNC1)Cl"	"NGYNBSHYFOFVLS-LBPRGKRZSA-N"	"InChI=1S/C19H21ClFN3O4S/c1-11-14(21)5-2-6-15(11)23-19(26)24-16-8-7-13(20)18(17(16)25)29(27,28)12-4-3-9-22-10-12/h2,5-8,12,22,25H,3-4,9-10H2,1H3,(H2,23,24,26)/t12-/m0/s1"	"yes"	""	"yes"
"10056"	"dapansutrile"	""	"Synthetic organic"	""	""	""	""	"375973244"	"12714644"	""	""	"CHEMBL3989943"	""	""	""	""	"3-methylsulfonylpropanenitrile"	"dapansutrile"	"OLT-1177|OLT1177"	"N#CCCS(=O)(=O)C"	"LQFRYKBDZNPJSW-UHFFFAOYSA-N"	"InChI=1S/C4H7NO2S/c1-8(6,7)4-2-3-5/h2,4H2,1H3"	"yes"	""	""
"11123"	"dapirolizumab pegol"	""	"Antibody"	""	""	""	""	"434122183"	""	""	""	"CHEMBL2109478"	""	""	""	""	""	"dapirolizumab pegol"	"CDP-7657|CDP7657|DZP"	""	""	""	"yes"	""	""
"6696"	"darapladib"	""	"Synthetic organic"	""	""	""	""	"178103307"	"9939609"	""	""	"CHEMBL204021"	""	""	""	""	"N-(2-diethylaminoethyl)-2-[2-[(4-fluorophenyl)methylsulfanyl]-4-oxo-6,7-dihydro-5H-cyclopenta[e]pyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide"	"darapladib"	"SB 480848|SB-480848"	"CCN(CCN(C(=O)Cn1c(SCc2ccc(cc2)F)nc(=O)c2c1CCC2)Cc1ccc(cc1)c1ccc(cc1)C(F)(F)F)CC"	"WDPFJWLDPVQCAJ-UHFFFAOYSA-N"	"InChI=1S/C36H38F4N4O2S/c1-3-42(4-2)20-21-43(22-25-8-12-27(13-9-25)28-14-16-29(17-15-28)36(38,39)40)33(45)23-44-32-7-5-6-31(32)34(46)41-35(44)47-24-26-10-18-30(37)19-11-26/h8-19H,3-7,20-24H2,1-2H3"	"yes"	""	""
"7395"	"daratumumab"	""	"Antibody"	"yes"	""	""	""	"178103967"	""	""	""	""	""	""	""	""	""	"daratumumab"	"3003-005|Darzalex&reg;|HuMax-CD38|JNJ-54767414"	""	""	""	"yes"	""	""
"5678"	"dasatinib"	""	"Synthetic organic"	"yes"	""	""	""	"178102305"	"3062316"	""	""	"CHEMBL1421"	""	""	""	""	"N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide"	"dasatinib"	"BMS 345825|BMS 354825|BMS 35482513|Sprycel&reg;"	"OCCN1CCN(CC1)c1cc(nc(n1)C)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl"	"ZBNZXTGUTAYRHI-UHFFFAOYSA-N"	"InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27)"	"yes"	""	""
"13453"	"dazodalibep"	""	"Peptide"	""	""	""	""	"500839863"	""	""	""	""	""	""	""	""	""	"dazodalibep"	"MEDI-4920|MEDI4920|VIB 4920|VIB-4920|VIB4920"	""	""	""	"yes"	""	""
"14524"	"dazukibart"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"dazukibart"	"PF-06823859|PF06823859"	""	""	""	"yes"	""	""
"10105"	"DDR1/2 inhibitor 5n"	""	"Synthetic organic"	""	""	""	""	"381118815"	"134693894"	""	""	""	""	""	""	""	"3-(2-imidazo[1,2-a]pyrazin-3-ylethynyl)-N-[3-[(4-methylpiperazin-1-yl)methyl]-5-(trifluoromethyl)phenyl]-4-propan-2-ylbenzamide"	""	""	"CN1CCN(CC1)Cc1cc(NC(=O)c2ccc(c(c2)C#Cc2cnc3n2ccnc3)C(C)C)cc(c1)C(F)(F)F"	"IUGBGEUCXVKGQK-UHFFFAOYSA-N"	"InChI=1S/C31H31F3N6O/c1-21(2)28-7-5-24(16-23(28)4-6-27-18-36-29-19-35-8-9-40(27)29)30(41)37-26-15-22(14-25(17-26)31(32,33)34)20-39-12-10-38(3)11-13-39/h5,7-9,14-19,21H,10-13,20H2,1-3H3,(H,37,41)"	"yes"	""	""
"8309"	"decernotinib"	""	"Synthetic organic"	""	""	""	""	"252166521"	"59422203"	""	""	"CHEMBL3039513"	""	""	""	""	"(2R)-2-methyl-2-[[2-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyrimidin-4-yl]amino]-N-(2,2,2-trifluoroethyl)butanamide"	"decernotinib"	"adelatinib|VRT-831509|VX-509"	"CC[C@](C(=O)NCC(F)(F)F)(Nc1ccnc(n1)c1c[nH]c2c1cccn2)C"	"ASUGUQWIHMTFJL-QGZVFWFLSA-N"	"InChI=1S/C18H19F3N6O/c1-3-17(2,16(28)25-10-18(19,20)21)27-13-6-8-23-15(26-13)12-9-24-14-11(12)5-4-7-22-14/h4-9H,3,10H2,1-2H3,(H,22,24)(H,25,28)(H,23,26,27)/t17-/m1/s1"	"yes"	""	""
"8714"	"dectrekumab"	""	"Antibody"	""	""	""	""	"252827372"	""	""	""	""	""	""	""	""	""	"dectrekumab"	"QAX-576|QAX576"	""	""	""	"yes"	""	""
"9477"	"deflazacort"	""	"Synthetic organic"	"yes"	""	""	""	"329968417"	"189821"	""	""	""	""	""	""	""	""	""	"Emflaza&reg;|MDL 458"	"CC(=O)OCC(=O)[C@@]12N=C(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1CCC1=CC(=O)C=C[C@]21C)C"	"FBHSPRKOSMHSIF-GRMWVWQJSA-N"	"InChI=1S/C25H31NO6/c1-13-26-25(20(30)12-31-14(2)27)21(32-13)10-18-17-6-5-15-9-16(28)7-8-23(15,3)22(17)19(29)11-24(18,25)4/h7-9,17-19,21-22,29H,5-6,10-12H2,1-4H3/t17-,18-,19-,21+,22+,23-,24-,25+/m0/s1"	"yes"	""	""
"9024"	"defoslimod"	""	"Synthetic organic"	""	""	""	""	"315661109"	"656812"	""	""	"CHEMBL2105854"	""	""	""	""	""	"defoslimod"	"OM 174|OM-174"	"CCCCCCCCCCC[C@H](CC(=O)N[C@H]1[C@H](O[C@@H]([C@H]([C@@H]1O)O)CO[C@@H]1O[C@H](CO)[C@H]([C@@H]([C@H]1NC(=O)C[C@@H](OC(=O)CCCCCCCCCCC)CCCCCCCCCCC)O)OP(=O)(O)O)OP(=O)(O)O)O"	"GOWLTLODGKPXMN-MEKRSRHXSA-N"	"InChI=1S/C52H100N2O20P2/c1-4-7-10-13-16-19-22-25-28-31-38(56)34-42(57)53-45-48(61)47(60)41(72-52(45)74-76(66,67)68)37-69-51-46(49(62)50(40(36-55)71-51)73-75(63,64)65)54-43(58)35-39(32-29-26-23-20-17-14-11-8-5-2)70-44(59)33-30-27-24-21-18-15-12-9-6-3/h38-41,45-52,55-56,60-62H,4-37H2,1-3H3,(H,53,57)(H,54,58)(H2,63,64,65)(H2,66,67,68)/t38-,39+,40-,41-,45-,46-,47-,48-,49-,50-,51-,52-/m1/s1"	"yes"	""	""
"9619"	"delgocitinib"	""	"Synthetic organic"	"yes"	""	""	""	"340590249"	"50914062"	""	""	""	""	""	""	""	""	"delgocitinib"	"Anzupgo&reg;|Corectim&reg;|ent-60|JTE-052|JTE052"	"N#CCC(=O)N1C[C@@H]([C@]21CCN(C2)c1ncnc2c1cc[nH]2)C"	"LOWWYYZBZNSPDT-ZBEGNZNMSA-N"	"InChI=1S/C16H18N6O/c1-11-8-22(13(23)2-5-17)16(11)4-7-21(9-16)15-12-3-6-18-14(12)19-10-20-15/h3,6,10-11H,2,4,7-9H2,1H3,(H,18,19,20)/t11-,16-/m0/s1"	"yes"	""	""
"7044"	"denileukin diftitox"	""	"Peptide"	"yes"	""	""	""	"178103623"	""	""	""	"CHEMBL1201550"	""	""	""	""	""	"denileukin diftitox"	"DAB389 IL2|denileukin diftitox-cxdl|LY 335348|Lymphir&reg;|Ontak&reg;"	""	""	""	"yes"	""	""
"14305"	"depemokimab"	""	"Antibody"	"yes"	""	""	""	"523352097"	""	""	""	""	""	""	""	""	""	"depemokimab"	"depemokimab-ulaa|Exdensur&reg;|GSK-3511294|GSK3511294"	""	""	""	"yes"	""	""
"7157"	"desloratadine"	""	"Synthetic organic"	"yes"	""	""	""	"178103732"	"124087"	""	""	"CHEMBL1172"	""	""	""	""	"8-chloro-11-piperidin-4-ylidene-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine"	"desloratadine"	"Clarinex&reg;|SCH-34117"	"Clc1ccc2c(c1)CCc1c(C2=C2CCNCC2)nccc1"	"JAUOIFJMECXRGI-UHFFFAOYSA-N"	"InChI=1S/C19H19ClN2/c20-16-5-6-17-15(12-16)4-3-14-2-1-9-22-19(14)18(17)13-7-10-21-11-8-13/h1-2,5-6,9,12,21H,3-4,7-8,10-11H2"	"yes"	""	""
"7066"	"desonide"	""	"Synthetic organic"	"yes"	""	""	""	"178103645"	"5311066"	""	""	"CHEMBL1201109"	""	""	""	""	""	"desonide"	"D-2083|Desowen&reg;"	"OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1CCC1=CC(=O)C=C[C@]21C)(C)C"	"WBGKWQHBNHJJPZ-LECWWXJVSA-N"	"InChI=1S/C24H32O6/c1-21(2)29-19-10-16-15-6-5-13-9-14(26)7-8-22(13,3)20(15)17(27)11-23(16,4)24(19,30-21)18(28)12-25/h7-9,15-17,19-20,25,27H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,20+,22-,23-,24+/m0/s1"	"yes"	""	""
"7067"	"desoximetasone"	""	"Metabolite"	"yes"	""	""	""	"178103646"	"5311067"	""	""	"CHEMBL1766"	""	""	""	""	"(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,11,12,14,15,16,17-octahydro-6H-cyclopenta[a]phenanthren-3-one"	"desoximetasone"	"A-41-304|HOE-304|R-2113|Topicort&reg;"	"OCC(=O)[C@H]1[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F"	"VWVSBHGCDBMOOT-IIEHVVJPSA-N"	"InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1"	"yes"	""	""
"10432"	"deucravacitinib"	""	"Synthetic organic"	"yes"	""	""	""	"385612192"	"134821691"	""	""	""	""	""	""	""	"6-(cyclopropanecarbonylamino)-4-[2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)anilino]-N-(trideuteriomethyl)pyridazine-3-carboxamide"	"deucravacitinib"	"BMS-986165|BMS986165|compound 11 [PMID: 31318208}|Sotyktu&reg;|Tyk2-IN-4"	"COc1c(cccc1c1ncn(n1)C)Nc1cc(nnc1C(=O)NC([2H])([2H])[2H])NC(=O)C1CC1"	"BZZKEPGENYLQSC-FIBGUPNXSA-N"	"InChI=1S/C20H22N8O3/c1-21-20(30)16-14(9-15(25-26-16)24-19(29)11-7-8-11)23-13-6-4-5-12(17(13)31-3)18-22-10-28(2)27-18/h4-6,9-11H,7-8H2,1-3H3,(H,21,30)(H2,23,24,25,29)/i1D3"	"yes"	""	""
"11410"	"deuruxolitinib"	""	"Synthetic organic"	"yes"	""	""	""	"440816779"	"72704611"	""	""	"CHEMBL4594381"	""	""	""	""	"(3R)-3-(2,2,3,3,4,4,5,5-octadeuteriocyclopentyl)-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile"	"deuruxolitinib"	"CTP-543|CTP543|D8-ruxolitinib|Leqselvi&reg;"	"N#CC[C@H](C1C([2H])([2H])C(C(C1([2H])[2H])([2H])[2H])([2H])[2H])n1ncc(c1)c1ncnc2c1cc[nH]2"	"HFNKQEVNSGCOJV-FBXGHSCESA-N"	"InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1/i1D2,2D2,3D2,4D2"	"yes"	""	""
"2768"	"dexamethasone"	""	"Synthetic organic"	"yes"	""	""	""	"135651471"	"5743"	""	""	"CHEMBL384467"	""	""	""	""	"(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one"	"dexamethasone"	"Decadron&reg;|desametasone|fluormethylprednisolone"	"OCC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F"	"UREBDLICKHMUKA-CXSFZGCWSA-N"	"InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1"	"yes"	""	""
"9728"	"dezapelisib"	""	"Synthetic organic"	""	""	""	""	"354702204"	"58111426"	""	""	"CHEMBL2216863"	""	""	""	""	"6-(3-fluorophenyl)-3-methyl-7-[(1S)-1-(7H-purin-6-ylamino)ethyl]-5H-[1,3]thiazolo[3,2-a]pyrimidin-5-one"	"dezapelisib"	"compound 67 [PMID: 22924688]|example 15 [WO2011008487]|INCB 40093|INCB40093"	"Fc1cccc(c1)c1c(nc2n(c1=O)c(C)cs2)[C@@H](Nc1ncnc2c1nc[nH]2)C"	"RSIWALKZYXPAGW-NSHDSACASA-N"	"InChI=1S/C20H16FN7OS/c1-10-7-30-20-27-15(11(2)26-18-16-17(23-8-22-16)24-9-25-18)14(19(29)28(10)20)12-4-3-5-13(21)6-12/h3-9,11H,1-2H3,(H2,22,23,24,25,26)/t11-/m0/s1"	"yes"	""	""
"14505"	"DF-003"	""	"Synthetic organic"	""	""	""	""	""	"171407492"	""	""	""	""	""	""	""	"N-[4-[(2S)-2-(4-chlorophenyl)but-3-yn-2-yl]-1,3-thiazol-2-yl]-2,6-difluoro-4-piperazin-1-ylbenzamide"	""	""	"C[C@@](C#C)(C1=CSC(NC(=O)C2=C(F)C=C(C=C2F)N3CCNCC3)=N1)C4=CC=C(Cl)C=C4"	"ANRFSQHHAOCNIN-DEOSSOPVSA-N"	"InChI=1S/C24H21ClF2N4OS/c1-3-24(2,15-4-6-16(25)7-5-15)20-14-33-23(29-20)30-22(32)21-18(26)12-17(13-19(21)27)31-10-8-28-9-11-31/h1,4-7,12-14,28H,8-11H2,2H3,(H,29,30,32)/t24-/m0/s1"	"yes"	""	""
"9082"	"diamorphine"	""	"Synthetic organic"	""	""	""	""	"315661167"	"5462328"	""	""	"CHEMBL459324"	""	""	""	""	"[(4R,4aR,7S,7aR,12bS)-9-acetyloxy-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7-yl] acetate"	""	"acetomorphine|diacetylmorphine|heroin"	"CC(=O)O[C@H]1C=C[C@@H]2[C@@]34[C@H]1Oc1c4c(C[C@H]2N(CC3)C)ccc1OC(=O)C"	"GVGLGOZIDCSQPN-PVHGPHFFSA-N"	"InChI=1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1"	"yes"	""	""
"2714"	"diclofenac"	""	"Synthetic organic"	"yes"	""	""	""	"135650177"	"3033"	""	""	"CHEMBL139"	""	""	""	""	"2-[2-[(2,6-dichlorophenyl)amino]phenyl]acetic acid"	"diclofenac"	"Cataflam&reg;|CGP-45840B|GP-45840|Voltaren&reg;|Voltarol&reg;"	"OC(=O)Cc1ccccc1Nc1c(Cl)cccc1Cl"	"DCOPUUMXTXDBNB-UHFFFAOYSA-N"	"InChI=1S/C14H11Cl2NO2/c15-10-5-3-6-11(16)14(10)17-12-7-2-1-4-9(12)8-13(18)19/h1-7,17H,8H2,(H,18,19)"	"yes"	""	""
"9776"	"difamilast"	""	"Synthetic organic"	"yes"	""	""	""	"354702249"	"57855696"	""	""	""	""	""	""	""	"N-[[2-[4-(difluoromethoxy)-3-propan-2-yloxyphenyl]-1,3-oxazol-4-yl]methyl]-2-ethoxybenzamide"	"difamilast"	"Adquey&reg;|example 352 [WO2007058338]|MM36|Moizerto&reg;|OPA-15406"	"CCOc1ccccc1C(=O)NCc1coc(n1)c1ccc(c(c1)OC(C)C)OC(F)F"	"VFBILHPIHUPBPZ-UHFFFAOYSA-N"	"InChI=1S/C23H24F2N2O5/c1-4-29-18-8-6-5-7-17(18)21(28)26-12-16-13-30-22(27-16)15-9-10-19(32-23(24)25)20(11-15)31-14(2)3/h5-11,13-14,23H,4,12H2,1-3H3,(H,26,28)"	"yes"	""	""
"9044"	"difelikefalin"	""	"Peptide"	"yes"	""	""	""	"315661129"	"24794466"	""	""	""	""	""	""	""	"4-amino-1-[(2R)-6-amino-2-[[(2R)-2-[[(2R)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid"	"difelikefalin"	"CR845|D-Phe-D-Phe-D-Leu-D-Lys-[&gamma;-(4-N-piperidinyl)amino carboxylic acid]|FE-202845|Kapruvia&reg;|Korsuva&reg;|SEQ ID NO: 2"	"NCCCC[C@H](C(=O)N1CCC(CC1)(N)C(=O)O)NC(=O)[C@H](NC(=O)[C@H](NC(=O)[C@@H](Cc1ccccc1)N)Cc1ccccc1)CC(C)C"	"FWMNVWWHGCHHJJ-SKKKGAJSSA-N"	"InChI=1S/C36H53N7O6/c1-24(2)21-29(32(45)40-28(15-9-10-18-37)34(47)43-19-16-36(39,17-20-43)35(48)49)42-33(46)30(23-26-13-7-4-8-14-26)41-31(44)27(38)22-25-11-5-3-6-12-25/h3-8,11-14,24,27-30H,9-10,15-23,37-39H2,1-2H3,(H,40,45)(H,41,44)(H,42,46)(H,48,49)/t27-,28-,29-,30-/m1/s1"	"yes"	""	""
"10080"	"diflapolin"	""	"Synthetic organic"	""	""	""	""	"375973267"	"4560409"	""	""	""	""	""	""	""	"1-[4-(1,3-benzothiazol-2-ylmethoxy)-2-methylphenyl]-3-(3,4-dichlorophenyl)urea"	""	""	"O=C(Nc1ccc(cc1C)OCc1nc2c(s1)cccc2)Nc1ccc(c(c1)Cl)Cl"	"FGXLEECGXSDIMM-UHFFFAOYSA-N"	"InChI=1S/C22H17Cl2N3O2S/c1-13-10-15(29-12-21-26-19-4-2-3-5-20(19)30-21)7-9-18(13)27-22(28)25-14-6-8-16(23)17(24)11-14/h2-11H,12H2,1H3,(H2,25,27,28)"	"yes"	""	""
"7068"	"diflorasone diacetate"	""	"Synthetic organic"	"yes"	""	""	""	"178103647"	"71414"	""	""	"CHEMBL1200545"	""	""	""	""	"[2-[(6S,8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyloxy-6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate"	"diflorasone"	"Psorcon&reg;|U-34865"	"CC(=O)O[C@@]1([C@@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F)C(=O)COC(=O)C"	"BOBLHFUVNSFZPJ-JOYXJVLSSA-N"	"InChI=1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1"	"yes"	""	""
"7162"	"diflunisal"	""	"Synthetic organic"	"yes"	""	""	""	"178103737"	"3059"	""	""	"CHEMBL898"	""	""	""	""	"5-(2,4-difluorophenyl)-2-hydroxybenzoic acid"	"diflunisal"	"Attrogy&reg;|Dolobid&reg;"	"Fc1ccc(c(c1)F)c1ccc(c(c1)C(=O)O)O"	"HUPFGZXOMWLGNK-UHFFFAOYSA-N"	"InChI=1S/C13H8F2O3/c14-8-2-3-9(11(15)6-8)7-1-4-12(16)10(5-7)13(17)18/h1-6,16H,(H,17,18)"	"yes"	""	""
"7474"	"difluprednate"	""	"Synthetic organic"	"yes"	""	""	""	"187051777"	"443936"	""	""	"CHEMBL1201749"	""	""	""	""	"[(6S,8S,9R,10S,11S,13S,14S,17R)-17-(2-acetyloxyacetyl)-6,9-difluoro-11-hydroxy-10,13-dimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] butanoate"	"difluprednate"	"DFBA|Durezol&reg;|W-6309"	"CCCC(=O)O[C@@]1(CC[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F)C(=O)COC(=O)C"	"WYQPLTPSGFELIB-JTQPXKBDSA-N"	"InChI=1S/C27H34F2O7/c1-5-6-23(34)36-26(22(33)14-35-15(2)30)10-8-17-18-12-20(28)19-11-16(31)7-9-24(19,3)27(18,29)21(32)13-25(17,26)4/h7,9,11,17-18,20-21,32H,5-6,8,10,12-14H2,1-4H3/t17-,18-,20-,21-,24-,25-,26-,27-/m0/s1"	"yes"	""	""
"7815"	"dilmapimod"	""	"Synthetic organic"	""	""	""	""	"223366146"	"10297982"	""	""	"CHEMBL2103838"	""	""	""	""	"8-(2,6-difluorophenyl)-2-(1,3-dihydroxypropan-2-ylamino)-4-(4-fluoro-2-methylphenyl)pyrido[6,5-d]pyrimidin-7-one"	"dilmapimod"	"SB-681323"	"OCC(Nc1nc(c2ccc(cc2C)F)c2c(n1)n(c(=O)cc2)c1c(F)cccc1F)CO"	"ORVNHOYNEHYKJG-UHFFFAOYSA-N"	"InChI=1S/C23H19F3N4O3/c1-12-9-13(24)5-6-15(12)20-16-7-8-19(33)30(21-17(25)3-2-4-18(21)26)22(16)29-23(28-20)27-14(10-31)11-32/h2-9,14,31-32H,10-11H2,1H3,(H,27,28,29)"	"yes"	""	""
"7045"	"dimethyl fumarate"	""	"Synthetic organic"	"yes"	""	""	""	"178103624"	"637568"	""	""	"CHEMBL2107333"	""	""	""	""	"dimethyl (E)-but-2-enedioate"	""	"BG-12|BG00012|fumaric acid|Tecfidera&reg;"	"COC(=O)/C=C/C(=O)OC"	"LDCRTTXIJACKKU-ONEGZZNKSA-N"	"InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+"	"yes"	""	""
"9939"	"dimethyl itaconate"	""	"Synthetic organic"	""	""	""	""	"363894233"	"69240"	""	""	""	""	""	""	""	"dimethyl 2-methylidenebutanedioate"	""	"dimethylitaconate|itaconic acid dimethyl ester"	"COC(=O)CC(=C)C(=O)OC"	"ZWWQRMFIZFPUAA-UHFFFAOYSA-N"	"InChI=1S/C7H10O4/c1-5(7(9)11-3)4-6(8)10-2/h1,4H2,2-3H3"	"yes"	""	""
"10101"	"dimetindene"	""	"Synthetic organic"	"yes"	""	""	""	"381118811"	"21855"	""	""	"CHEMBL22108"	""	""	""	""	"N,N-dimethyl-2-[3-(1-pyridin-2-ylethyl)-1H-inden-2-yl]ethanamine"	"dimetindene"	"(+/-)-dimethindene|dimethindene|dimethpyrindene|Fenistil&reg;|Vibrocil&reg;"	"CN(CCC1=C(C(c2ccccn2)C)c2c(C1)cccc2)C"	"MVMQESMQSYOVGV-UHFFFAOYSA-N"	"InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3"	"yes"	""	""
"10307"	"diminazene"	""	"Synthetic organic"	""	""	""	""	"381744988"	"2354"	""	""	"CHEMBL35241"	""	""	""	""	""	""	"Azidin&reg;|Berenil&reg;|Pirocide&reg;"	"NC(=N)c1ccc(cc1)NN=Nc1ccc(cc1)C(=N)N"	"XNYZHCFCZNMTFY-UHFFFAOYSA-N"	"InChI=1S/C14H15N7/c15-13(16)9-1-5-11(6-2-9)19-21-20-12-7-3-10(4-8-12)14(17)18/h1-8H,(H3,15,16)(H3,17,18)(H,19,20)"	"yes"	""	""
"7379"	"dinaciclib"	""	"Synthetic organic"	""	""	""	""	"178103951"	"46926350"	""	""	"CHEMBL2103840"	""	""	""	""	"2-[(2S)-1-[3-ethyl-7-[(1-oxidopyridin-1-ium-3-yl)methylamino]pyrazolo[1,5-a]pyrimidin-5-yl]piperidin-2-yl]ethanol"	"dinaciclib"	"SCH727965"	"OCC[C@@H]1CCCCN1c1cc(NCc2ccc[n+](c2)[O-])n2c(n1)c(CC)cn2"	"PIMQWRZWLQKKBJ-SFHVURJKSA-N"	"InChI=1S/C21H28N6O2/c1-2-17-14-23-27-19(22-13-16-6-5-9-25(29)15-16)12-20(24-21(17)27)26-10-4-3-7-18(26)8-11-28/h5-6,9,12,14-15,18,22,28H,2-4,7-8,10-11,13H2,1H3/t18-/m0/s1"	"yes"	""	""
"7165"	"diphenylpyraline"	""	"Synthetic organic"	"yes"	""	""	""	"178103740"	"3103"	""	""	"CHEMBL1492"	""	""	""	""	"4-(diphenylmethoxy)-1-methylpiperidine"	"diphenylpyraline"	"Hispril&reg;"	"CN1CCC(CC1)OC(c1ccccc1)c1ccccc1"	"OWQUZNMMYNAXSL-UHFFFAOYSA-N"	"InChI=1S/C19H23NO/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-19H,12-15H2,1H3"	"yes"	""	""
"10341"	"diprovocim-1"	""	"Synthetic organic"	""	""	""	""	"381745022"	"137553173"	""	""	""	""	""	""	""	"(3S,4S)-1-{4-[(3S,4S)-3,4-bis({[(1S,2R)-2-phenylcyclopropyl]carbamoyl})pyrrolidine-1-carbonyl]benzoyl}-N3,N4-bis[(1S,2R)-2-phenylcyclopropyl]pyrrolidine-3,4-dicarboxamide"	""	"compound 3 [PMID: 30272974]"	"O=C(c1ccc(cc1)C(=O)N1C[C@H]([C@@H](C1)C(=O)N[C@H]1C[C@@H]1c1ccccc1)C(=O)N[C@H]1C[C@@H]1c1ccccc1)N1C[C@H]([C@@H](C1)C(=O)N[C@H]1C[C@@H]1c1ccccc1)C(=O)N[C@H]1C[C@@H]1c1ccccc1"	"ABZBNXFGYUSVCJ-UYMKNZQYSA-N"	"InChI=1S/C56H56N6O6/c63-51(57-47-25-39(47)33-13-5-1-6-14-33)43-29-61(30-44(43)52(64)58-48-26-40(48)34-15-7-2-8-16-34)55(67)37-21-23-38(24-22-37)56(68)62-31-45(53(65)59-49-27-41(49)35-17-9-3-10-18-35)46(32-62)54(66)60-50-28-42(50)36-19-11-4-12-20-36/h1-24,39-50H,25-32H2,(H,57,63)(H,58,64)(H,59,65)(H,60,66)/t39-,40-,41-,42-,43-,44-,45-,46-,47+,48+,49+,50+/m1/s1"	"yes"	""	""
"9775"	"diroleuton"	""	"Synthetic organic"	""	""	""	""	"354702248"	"5280581"	""	""	"CHEMBL465183"	""	""	""	""	"(8Z,11Z,14Z)-icosa-8,11,14-trienoic acid"	"diroleuton"	"8,11,14-Eicosatrienoic acid|DGLA|dihomo-gamma-linolenic acid|DS107|Homo-gamma-linolenic acid"	"CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O"	"HOBAELRKJCKHQD-QNEBEIHSSA-N"	"InChI=1S/C20H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(21)22/h6-7,9-10,12-13H,2-5,8,11,14-19H2,1H3,(H,21,22)/b7-6-,10-9-,13-12-"	"yes"	""	""
"10525"	"diroximel fumarate"	""	"Synthetic organic"	"yes"	""	""	""	"387065607"	"73330464"	""	""	"CHEMBL3989944"	""	""	""	""	"4-O-[2-(2,5-dioxopyrrolidin-1-yl)ethyl] 1-O-methyl (E)-but-2-enedioate"	"diroximel fumarate"	"ALKS-8700|ALKS8700|BIIB098|Vumerity&reg;"	"COC(=O)/C=C/C(=O)OCCN1C(=O)CCC1=O"	"YIMYDTCOUQIDMT-SNAWJCMRSA-N"	"InChI=1S/C11H13NO6/c1-17-10(15)4-5-11(16)18-7-6-12-8(13)2-3-9(12)14/h4-5H,2-3,6-7H2,1H3/b5-4+"	"yes"	""	""
"13087"	"divozilimab"	""	"Antibody"	"yes"	""	""	""	"491299869"	""	""	""	""	""	""	""	""	""	"divozilimab"	"BCD 132|BCD-132|Ivlizi&reg;"	""	""	""	"yes"	""	""
"9323"	"DMAT"	""	"Synthetic organic"	""	""	""	""	"318164842"	"5326976"	""	""	"CHEMBL376505"	""	""	""	""	"4,5,6,7-TETRABROMO-N,N-DIMETHYL-1H-BENZIMIDAZOL-2-AMINE"	""	"2-Dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole|CK2 Inhibitor II"	"CN(c1[nH]c2c(n1)c(Br)c(c(c2Br)Br)Br)C"	"SLPJGDQJLTYWCI-UHFFFAOYSA-N"	"InChI=1S/C9H7Br4N3/c1-16(2)9-14-7-5(12)3(10)4(11)6(13)8(7)15-9/h1-2H3,(H,14,15)"	"yes"	""	""
"10250"	"DO264"	""	"Synthetic organic"	""	""	""	""	"381744932"	"134813646"	""	""	""	""	""	""	""	"1-[1-[3-chloro-4-[2-chloro-4-(trifluoromethoxy)phenoxy]pyridin-2-yl]piperidin-4-yl]-3-pyridin-3-ylthiourea"	""	"compound 46|DO-264"	"S=C(Nc1cccnc1)NC1CCN(CC1)c1nccc(c1Cl)Oc1ccc(cc1Cl)OC(F)(F)F"	"PIEQDBPBBQPLPL-UHFFFAOYSA-N"	"InChI=1S/C23H20Cl2F3N5O2S/c24-17-12-16(35-23(26,27)28)3-4-18(17)34-19-5-9-30-21(20(19)25)33-10-6-14(7-11-33)31-22(36)32-15-2-1-8-29-13-15/h1-5,8-9,12-14H,6-7,10-11H2,(H2,31,32,36)"	"yes"	""	""
"13983"	"domvanalimab"	""	"Antibody"	""	""	""	""	"518520610"	""	""	""	""	""	""	""	""	""	"domvanalimab"	"AB-154|AB154"	""	""	""	"yes"	""	""
"940"	"dopamine"	""	"Metabolite"	"yes"	""	""	""	"135651480"	"681"	""	""	"CHEMBL59"	""	""	""	""	"4-(2-Aminoethyl)benzene-1,2-diol"	"dopamine"	"3-hydroxytyramine"	"NCCc1ccc(c(c1)O)O"	"VYFYYTLLBUKUHU-UHFFFAOYSA-N"	"InChI=1S/C8H11NO2/c9-4-3-6-1-2-7(10)8(11)5-6/h1-2,5,10-11H,3-4,9H2"	"yes"	""	""
"5668"	"doramapimod"	""	"Synthetic organic"	""	""	""	""	"178102296"	"156422"	""	""	"CHEMBL103667"	""	""	""	""	"3-[3-tert-butyl-1-(4-methylphenyl)-1H-pyrazol-5-yl]-1-{4-[2-(morpholin-4-yl)ethoxy]naphthalen-1-yl}urea"	"doramapimod"	"BIRB 796BS|BIRB-796|BIRB796"	"O=C(Nc1cc(nn1c1ccc(cc1)C)C(C)(C)C)Nc1ccc(c2c1cccc2)OCCN1CCOCC1"	"MVCOAUNKQVWQHZ-UHFFFAOYSA-N"	"InChI=1S/C31H37N5O3/c1-22-9-11-23(12-10-22)36-29(21-28(34-36)31(2,3)4)33-30(37)32-26-13-14-27(25-8-6-5-7-24(25)26)39-20-17-35-15-18-38-19-16-35/h5-14,21H,15-20H2,1-4H3,(H2,32,33,37)"	"yes"	""	""
"9978"	"dordaviprone"	""	"Synthetic organic"	"yes"	""	""	""	"374883865"	"73777259"	""	""	"CHEMBL4297310"	""	""	""	""	""	"dordaviprone"	"Modeyso&reg;|ONC-201|ONC201|TIC-10|TIC10"	"Cc1ccccc1Cn1c(=O)c2CN(CCc2n2c1=NCC2)Cc1ccccc1"	"VLULRUCCHYVXOH-UHFFFAOYSA-N"	"InChI=1S/C24H26N4O/c1-18-7-5-6-10-20(18)16-28-23(29)21-17-26(15-19-8-3-2-4-9-19)13-11-22(21)27-14-12-25-24(27)28/h2-10H,11-17H2,1H3"	"yes"	""	""
"11518"	"dostarlimab"	""	"Antibody"	"yes"	""	""	""	"441604890"	""	""	""	""	""	""	""	""	""	"dostarlimab"	"ANB-011|dostarlimab-gxly|Jemperli&reg;|TSR-042|WBP-285"	""	""	""	"yes"	""	""
"6464"	"doxycycline"	""	"Synthetic organic"	"yes"	""	""	""	"178103078"	"54671203"	""	""	"CHEMBL1433"	""	""	""	""	"(4S,4aR,5S,5aR,6R,12aR)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide"	"doxycycline"	"BMY-28689|Monodox&reg;|Vibramycin&reg;"	"CN([C@@H]1C(=O)C(=C([C@@]2([C@H]1[C@@H](O)[C@@H]1[C@@H](C)c3cccc(c3C(=C1C2=O)O)O)O)O)C(=O)N)C"	"SGKRLCUYIXIAHR-AKNGSSGZSA-N"	"InChI=1S/C22H24N2O8/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29/h4-7,10,14-15,17,25-27,30,32H,1-3H3,(H2,23,31)/t7-,10+,14+,15-,17-,22-/m0/s1"	"yes"	"yes"	"yes"
"10124"	"dual sEH/FAAH inhibitor 11"	""	"Synthetic organic"	""	""	""	""	"381118834"	"130431484"	""	""	""	""	""	""	""	"N-[4-(trifluoromethoxy)phenyl]-4-[(3-{[5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)methyl]piperidine-1-carboxamide"	""	"compound B-11 [WO2017160861]|example 28 [WO2017160861]"	"O=C(N1CCC(CC1)Cc1cccc(c1)Oc1ccc(cn1)C(F)(F)F)Nc1ccc(cc1)OC(F)(F)F"	"LWLSVNFEVKJDBZ-UHFFFAOYSA-N"	"InChI=1S/C26H23F6N3O3/c27-25(28,29)19-4-9-23(33-16-19)37-22-3-1-2-18(15-22)14-17-10-12-35(13-11-17)24(36)34-20-5-7-21(8-6-20)38-26(30,31)32/h1-9,15-17H,10-14H2,(H,34,36)"	"yes"	""	""
"8863"	"dubermatinib"	""	"Synthetic organic"	""	""	""	""	"252827520"	"56839178"	""	""	"CHEMBL2022968"	""	""	""	""	"2-((5-chloro-2-((4-((4-methylpiperazin-1-yl)methyl)phenyl)amino)pyrimidin-4-yl)amino)-N,N-dimethylbenzenesulfonamide"	"dubermatinib"	"compound 13|TP 0903|TP-0903|TP0903"	"CN1CCN(CC1)Cc1ccc(cc1)Nc1ncc(c(n1)Nc1ccccc1S(=O)(=O)N(C)C)Cl"	"YUAALFPUEOYPNX-UHFFFAOYSA-N"	"InChI=1S/C24H30ClN7O2S/c1-30(2)35(33,34)22-7-5-4-6-21(22)28-23-20(25)16-26-24(29-23)27-19-10-8-18(9-11-19)17-32-14-12-31(3)13-15-32/h4-11,16H,12-15,17H2,1-3H3,(H2,26,27,28,29)"	"yes"	""	""
"7574"	"dupilumab"	""	"Antibody"	"yes"	""	""	""	"223365910"	""	""	""	""	""	""	""	""	""	"dupilumab"	"Dupixent&reg;|REGN668|SAR231893"	""	""	""	"yes"	""	""
"7985"	"durvalumab"	""	"Antibody"	"yes"	""	""	""	"249565666"	""	""	""	""	""	""	""	""	""	"durvalumab"	"anti-B7H1 monoclonal antibody|Imfinzi&reg;|MEDI-4736|MEDI4736"	""	""	""	"yes"	""	""
"14420"	"duvakitug"	""	"Antibody"	""	""	""	""	"523352212"	""	""	""	""	""	""	""	""	""	"duvakitug"	"TEV-48574|TEV48574"	""	""	""	"yes"	""	""
"7795"	"duvelisib"	""	"Synthetic organic"	"yes"	""	""	""	"223366126"	"50905713"	""	""	"CHEMBL3039502"	""	""	""	""	"(S)-3-(1-((9H-purin-6-yl)amino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one"	"duvelisib"	"compound 4904 [Patent US8193182]|Copiktra&reg;|INK-1197|IPI-145"	"Clc1cccc2c1c(=O)n(c(c2)[C@@H](Nc1ncnc2c1[nH]cn2)C)c1ccccc1"	"SJVQHLPISAIATJ-ZDUSSCGKSA-N"	"InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1"	"yes"	""	""
"9959"	"DX-2507"	""	"Antibody"	""	""	""	""	"374883846"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"7070"	"dyphylline"	""	"Metabolite"	"yes"	""	""	""	"178103649"	"3182"	""	""	"CHEMBL1752"	""	""	""	""	"7-(2,3-dihydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione"	"diprophylline"	"Dilor&reg;"	"OCC(Cn1cnc2c1c(=O)n(C)c(=O)n2C)O"	"KSCFJBIXMNOVSH-UHFFFAOYSA-N"	"InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3"	"yes"	""	""
"10431"	"E-52862"	""	"Synthetic organic"	""	""	""	""	"385612191"	"44247568"	""	""	"CHEMBL2170062"	""	""	""	""	"4-[2-(5-methyl-1-naphthalen-2-ylpyrazol-3-yl)oxyethyl]morpholine"	""	"compound 28 [PMID: 22784008]|E52862|MR309|sigma 1 receptor antagonist (S1RA)"	"Cc1cc(nn1c1ccc2c(c1)cccc2)OCCN1CCOCC1"	"DGPGXHRHNRYVDH-UHFFFAOYSA-N"	"InChI=1S/C20H23N3O2/c1-16-14-20(25-13-10-22-8-11-24-12-9-22)21-23(16)19-7-6-17-4-2-3-5-18(17)15-19/h2-7,14-15H,8-13H2,1H3"	"yes"	""	""
"7836"	"E6201"	""	"Synthetic organic"	""	""	""	""	"223366167"	"10172827"	""	""	"CHEMBL1097999"	""	""	""	""	"(4S,5R,6Z,9S,10S,12E)-16-ethylamino-9,10,18-trihydroxy-4,5-dimethyl-3-oxabicyclo[12.4.0]octadeca-1(14),6,12,15,17-pentaene-2,8-dione"	""	"E 6201|E-6201"	"CCNc1cc2/C=C/C[C@H](O)[C@H](O)C(=O)/C=C\[C@H]([C@@H](OC(=O)c2c(c1)O)C)C"	"MWUFVYLAWAXDHQ-HMNLTAHHSA-N"	"InChI=1S/C21H27NO6/c1-4-22-15-10-14-6-5-7-16(23)20(26)17(24)9-8-12(2)13(3)28-21(27)19(14)18(25)11-15/h5-6,8-13,16,20,22-23,25-26H,4,7H2,1-3H3/b6-5+,9-8-/t12-,13+,16+,20+/m1/s1"	"yes"	""	""
"13875"	"ebdarokimab"	""	"Antibody"	"yes"	""	""	""	"513757560"	""	""	""	""	""	""	""	""	""	"ebdarokimab"	"Aidaro&reg; (China)|AK-101|AK101"	""	""	""	"yes"	""	""
"6955"	"ecallantide"	""	"Peptide"	"yes"	""	""	""	"178103537"	"44152182"	""	""	"CHEMBL1201837"	""	""	""	""	""	"ecallantide"	"DX-88|FOV2302|Kalbitor&reg;"	"CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@H]2CSSC[C@H]3C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N4CCC[C@H]4C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N4CCC[C@H]4C(=O)N3)CC(=O)O)CC(=O)O)C)CCCCN)Cc3ccccc3)C)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CO)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@H](CCSC)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)O)N)C(=O)N[C@@H]([C@H](C)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)O)CCSC)CCCCN)CCCCN)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC2=O)CCC(=O)O)CC(=O)N)CCC(=O)N)CC(=O)N)CCCNC(=N)N)Cc2ccccc2)CCC(=O)O)CO)CC(C)C)CCC(=O)O)CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)Cc1ccccc1)CCC(=O)O)CCC(=O)O)CCC(=O)N)CCCNC(=N)N)[C@H](C)O)Cc1ccccc1)[C@@H](C)CC)CC(=O)N)Cc1ccccc1)Cc1ccccc1)Cc1c[nH]c2ccccc12)CCCNC(=N)N)Cc1cnc[nH]1)C)C)CCCNC(=N)N)Cc1ccc(cc1)O"	"VBGWSQKGUZHFPS-VGMMZINCSA-N"	""	"yes"	""	""
"11308"	"eclitasertib"	""	"Synthetic organic"	""	""	""	""	"434321743"	"130298939"	""	""	"CHEMBL4861471"	""	""	""	""	"5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydropyrido[3,2-b][1,4]oxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide"	"eclitasertib"	"DNL-758|DNL758|example 42 [WO2017136727A2]|SAR443122"	"O=C1[C@H](COc2c(N1C)nccc2)NC(=O)c1n[nH]c(n1)Cc1ccccc1"	"XUZICJHIIJCKQQ-ZDUSSCGKSA-N"	"InChI=1S/C19H18N6O3/c1-25-17-14(8-5-9-20-17)28-11-13(19(25)27)21-18(26)16-22-15(23-24-16)10-12-6-3-2-4-7-12/h2-9,13H,10-11H2,1H3,(H,21,26)(H,22,23,24)/t13-/m0/s1"	"yes"	""	""
"6884"	"eculizumab"	""	"Antibody"	"yes"	""	""	""	"178103466"	""	""	""	""	""	""	""	""	""	"eculizumab"	"h5G1.1|h5G1.1VHC|Soliris&reg;"	""	""	""	"yes"	""	""
"8942"	"edicotinib"	""	"Synthetic organic"	""	""	""	""	"310264723"	"25230468"	""	""	""	""	""	""	""	"4-cyano-N-[2-(4,4-dimethylcyclohex-1-en-1-yl)-6-(2,2,6,6-tetramethyloxan-4-yl)pyridin-3-yl]-1H-imidazole-2-carboxamide"	"edicotinib"	"JNJ-40346527|JNJ40346527|US8497376, 15"	"N#Cc1c[nH]c(n1)C(=O)Nc1ccc(nc1C1=CCC(CC1)(C)C)C1CC(C)(C)OC(C1)(C)C"	"BNVPFDRNGHMRJS-UHFFFAOYSA-N"	"InChI=1S/C27H35N5O2/c1-25(2)11-9-17(10-12-25)22-21(32-24(33)23-29-16-19(15-28)30-23)8-7-20(31-22)18-13-26(3,4)34-27(5,6)14-18/h7-9,16,18H,10-14H2,1-6H3,(H,29,30)(H,32,33)"	"yes"	""	""
"6593"	"efalizumab"	""	"Antibody"	"yes"	"yes"	""	""	"178103206"	""	""	""	"CHEMBL1201575"	""	""	""	""	""	"efalizumab"	"anti alphaL integrin|antiCD11 alpha|hu1124|Raptiva&reg;"	""	""	""	"yes"	""	""
"9777"	"efgartigimod alfa"	""	"Antibody"	"yes"	""	""	""	"354702250"	""	""	""	""	""	""	""	""	""	"efgartigimod alfa"	"ARGX-113|efgartigimod alfa-fcab|Vyvgart&reg;"	""	""	""	"yes"	""	""
"11097"	"efineptakin alfa"	""	"Peptide"	""	""	""	""	"434122158"	""	""	""	""	""	""	""	""	""	"efineptakin alfa"	"GX-I7|Hyleukin-7|Il-7 hybrid Fc|NT-I7|rhIL-7-hyFc|TJ-107"	""	""	""	"yes"	""	""
"13199"	"efzofitimod"	""	"Peptide"	""	""	""	""	"491299981"	""	""	""	""	""	""	""	""	""	"efzofitimod"	"ATYR-1923|ATYR1923|KRP-R120"	""	""	""	"yes"	""	""
"9904"	"EG01377"	""	"Synthetic organic"	""	""	""	""	"363894198"	"133081972"	""	""	""	""	""	""	""	"(2S)-2-[(3-{5-[4-(aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-7-sulfonamido}thiophen-2-yl)formamido]-5-carbamimidamidopentanoic acid"	""	"(3-((5-(4-(aminomethyl)phenyl)-2,3-dihydrobenzofuran)-7-sulfonamido)thiophene- 2-carbonyl)-L-arginine|compound 1 [PMID: 29648813]"	"NCc1ccc(cc1)c1cc2CCOc2c(c1)S(=O)(=O)Nc1ccsc1C(=O)N[C@H](C(=O)O)CCCNC(=N)N"	"SEXUXSMBJLNXIR-FQEVSTJZSA-N"	"InChI=1S/C26H30N6O6S2/c27-14-15-3-5-16(6-4-15)18-12-17-7-10-38-22(17)21(13-18)40(36,37)32-19-8-11-39-23(19)24(33)31-20(25(34)35)2-1-9-30-26(28)29/h3-6,8,11-13,20,32H,1-2,7,9-10,14,27H2,(H,31,33)(H,34,35)(H4,28,29,30)/t20-/m0/s1"	"yes"	""	""
"9563"	"eganelisib"	""	"Synthetic organic"	""	""	""	""	"336446949"	"91933883"	""	""	""	""	""	""	""	"2-amino-N-[(1S)-1-[8-[2-(1-methylpyrazol-4-yl)ethynyl]-1-oxo-2-phenylisoquinolin-3-yl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide"	"eganelisib"	"compound 26 [PMID: 27660692]|IPI-549|IPI549"	"Cn1ncc(c1)C#Cc1cccc2c1c(=O)n(c(c2)[C@@H](NC(=O)c1c(N)nn2c1nccc2)C)c1ccccc1"	"XUMALORDVCFWKV-IBGZPJMESA-N"	"InChI=1S/C30H24N8O2/c1-19(34-29(39)26-27(31)35-37-15-7-14-32-28(26)37)24-16-22-9-6-8-21(13-12-20-17-33-36(2)18-20)25(22)30(40)38(24)23-10-4-3-5-11-23/h3-11,14-19H,1-2H3,(H2,31,35)(H,34,39)/t19-/m0/s1"	"yes"	""	""
"12035"	"elafin"	"Human"	"Peptide"	""	""	""	""	"464244176"	""	"P19957"	"ENSG00000124102"	""	""	""	""	""	""	""	"cementoin|trappin-2"	""	""	""	"yes"	""	""
"9047"	"eldelumab"	""	"Antibody"	""	""	""	""	"315661132"	""	""	""	""	""	""	""	""	""	"eldelumab"	"BMS-936557|MDX-1100"	""	""	""	"yes"	""	""
"12357"	"elenestinib"	""	"Synthetic organic"	""	""	""	""	"479821148"	"155190269"	""	""	""	""	""	""	""	"2-[4-[4-[4-[5-[(1S)-1-amino-1-(4-fluorophenyl)ethyl]pyrimidin-2-yl]piperazin-1-yl]pyrrolo[2,1-f][1,2,4]triazin-6-yl]pyrazol-1-yl]ethanol"	"elenestinib"	"BLU-263|BLU263|exampl4 4 [WO2020210293A1]"	"C[C@](c1ccc(cc1)F)(c1cnc(nc1)N1CCN(CC1)c1ncnn2c1cc(c2)c1cn(nc1)CCO)N"	"IPMARPMXSFFZFG-MHZLTWQESA-N"	"InChI=1S/C27H29FN10O/c1-27(29,21-2-4-23(28)5-3-21)22-14-30-26(31-15-22)36-8-6-35(7-9-36)25-24-12-19(17-38(24)34-18-32-25)20-13-33-37(16-20)10-11-39/h2-5,12-18,39H,6-11,29H2,1H3/t27-/m0/s1"	"yes"	""	""
"9290"	"elezanumab"	""	"Antibody"	""	""	""	""	"318164809"	""	""	""	""	""	""	""	""	""	"elezanumab"	"ABT-555|AE12-1Y-QL"	""	""	""	"yes"	""	""
"8361"	"elotuzumab"	""	"Antibody"	"yes"	""	""	""	"252166573"	""	""	""	""	""	""	""	""	""	"elotuzumab"	"BMS-901608|Empliciti&reg;|HuLuc63"	""	""	""	"yes"	""	""
"12889"	"elranatamab"	""	"Antibody"	"yes"	""	""	""	"485206010"	""	""	""	""	""	""	""	""	""	"elranatamab"	"elranatamab-bcmm|Elrexfio&reg;|PF-06863135|PF06863135"	""	""	""	"yes"	""	""
"10464"	"elsubrutinib"	""	"Synthetic organic"	""	""	""	""	"385612224"	"117773770"	""	""	""	""	""	""	""	"4-[(3S)-1-prop-2-enoylpiperidin-3-yl]-1H-indole-7-carboxamide"	"elsubrutinib"	"example #30 (S) [WO2014210255A1]"	"C=CC(=O)N1CCC[C@H](C1)c1ccc(c2c1cc[nH]2)C(=O)N"	"UNHZLHSLZZWMNP-LLVKDONJSA-N"	"InChI=1S/C17H19N3O2/c1-2-15(21)20-9-3-4-11(10-20)12-5-6-14(17(18)22)16-13(12)7-8-19-16/h2,5-8,11,19H,1,3-4,9-10H2,(H2,18,22)/t11-/m1/s1"	"yes"	""	""
"8499"	"elubirixin"	""	"Synthetic organic"	""	""	""	""	"252166707"	"10479502"	""	""	"CHEMBL2178579"	""	""	""	""	"3-(2-chloro-3-fluorophenyl)-1-(4-chloro-2-hydroxy-3-piperazin-1-ylsulfonylphenyl)urea"	"elubrixin"	"SB 656933|SB-656933|SB656933"	"O=C(Nc1cccc(c1Cl)F)Nc1ccc(c(c1O)S(=O)(=O)N1CCNCC1)Cl"	"YQYFEGTYCUQBEI-UHFFFAOYSA-N"	"InChI=1S/C17H17Cl2FN4O4S/c18-10-4-5-13(23-17(26)22-12-3-1-2-11(20)14(12)19)15(25)16(10)29(27,28)24-8-6-21-7-9-24/h1-5,21,25H,6-9H2,(H2,22,23,26)"	"yes"	""	""
"8944"	"emactuzumab"	""	"Antibody"	""	""	""	""	"310264725"	""	""	""	""	""	""	""	""	""	"emactuzumab"	"RG7155|RO5509554"	""	""	""	"yes"	""	""
"9295"	"emapalumab"	""	"Antibody"	"yes"	""	""	""	"318164814"	""	""	""	""	""	""	""	""	""	"emapalumab"	"emapalumab-lzsg|Gamifant&reg;|NI-0501|NI0501"	""	""	""	"yes"	""	""
"10152"	"emavusertib"	""	"Synthetic organic"	""	""	""	""	"381118862"	"118224491"	""	""	""	""	""	""	""	""	"emavusertib"	"AU-4948|AU4948|CA4948|compound 24 [PMID: 33335659]"	"O[C@@H]1CCN(C1)c1nc2nc(oc2cc1NC(=O)c1coc(n1)c1ccnc(c1)C)N1CCOCC1"	"SJHNWSAWWOAWJH-MRXNPFEDSA-N"	"InChI=1S/C24H25N7O5/c1-14-10-15(2-4-25-14)23-27-18(13-35-23)22(33)26-17-11-19-20(28-21(17)31-5-3-16(32)12-31)29-24(36-19)30-6-8-34-9-7-30/h2,4,10-11,13,16,32H,3,5-9,12H2,1H3,(H,26,33)/t16-/m1/s1"	"yes"	""	""
"12172"	"emlenoflast"	""	"Synthetic organic"	""	""	""	""	"472319294"	"122480653"	""	""	"CHEMBL4650350"	""	""	""	""	"1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-(1-propan-2-ylpyrazol-3-yl)sulfonylurea"	"emlenoflast"	"Inzomelid|MCC-7840|MCC7840"	"CC(C)n1ccc(n1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2c1CCC2"	"MTOUOUSKXWSTAX-UHFFFAOYSA-N"	"InChI=1S/C19H24N4O3S/c1-12(2)23-10-9-17(21-23)27(25,26)22-19(24)20-18-15-7-3-5-13(15)11-14-6-4-8-16(14)18/h9-12H,3-8H2,1-2H3,(H2,20,22,24)"	"yes"	""	""
"9773"	"enexasogaol"	""	"Natural product"	""	""	""	""	"354702246"	"5281794"	""	""	"CHEMBL25948"	""	""	""	""	"(E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one"	"enexasogaol"	"6-Shogaol|[6]-shogaol|trans-6-shogaol"	"CCCCC/C=C/C(=O)CCc1ccc(c(c1)OC)O"	"OQWKEEOHDMUXEO-BQYQJAHWSA-N"	"InChI=1S/C17H24O3/c1-3-4-5-6-7-8-15(18)11-9-14-10-12-16(19)17(13-14)20-2/h7-8,10,12-13,19H,3-6,9,11H2,1-2H3/b8-7+"	"yes"	""	""
"9589"	"enoblituzumab"	""	"Antibody"	""	""	""	""	"340590220"	""	""	""	""	""	""	""	""	""	"enoblituzumab"	"MGA-271|MGA271"	""	""	""	"yes"	""	""
"8934"	"enokizumab"	""	"Antibody"	""	""	""	""	"310264715"	""	""	""	""	""	""	""	""	""	"enokizumab"	"7F3com-2H2|MEDI-528|MEDI528"	""	""	""	"yes"	""	""
"11307"	"enpatoran"	""	"Synthetic organic"	""	""	""	""	"434321742"	"129240620"	""	""	""	""	""	""	""	"5-[(3R,5S)-3-amino-5-(trifluoromethyl)piperidin-1-yl]quinoline-8-carbonitrile"	"enpatoran"	"compound 73 [WO2017106607A1]|M-5049|M5049"	"N#Cc1ccc(c2c1nccc2)N1C[C@H](N)C[C@@H](C1)C(F)(F)F"	"BJXYHBKEQFQVES-NWDGAFQWSA-N"	"InChI=1S/C16H15F3N4/c17-16(18,19)11-6-12(21)9-23(8-11)14-4-3-10(7-20)15-13(14)2-1-5-22-15/h1-5,11-12H,6,8-9,21H2/t11-,12+/m0/s1"	"yes"	""	""
"13937"	"ENPP1 inhibitor 27"	""	"Synthetic organic"	""	""	""	""	"513757622"	"168990978"	""	""	""	""	""	""	""	"[4-[(7-methoxy-1,8-naphthyridin-4-yl)oxy]phenyl]methylphosphonic acid"	""	""	"COC1=CC=C2C(OC3=CC=C(CP(O)(O)=O)C=C3)=CC=NC2=N1"	"OMZZUXIAISGIOK-UHFFFAOYSA-N"	"InChI=1S/C16H15N2O5P/c1-22-15-7-6-13-14(8-9-17-16(13)18-15)23-12-4-2-11(3-5-12)10-24(19,20)21/h2-9H,10H2,1H3,(H2,19,20,21)"	"yes"	""	""
"11865"	"ensifentrine"	""	"Synthetic organic"	"yes"	""	""	""	"461663421"	"9934746"	""	""	"CHEMBL4594287"	""	""	""	""	"2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea"	"ensifentrine"	"Ohtuvayre&reg;|RPL554|VMX 554|VMX-554|VMX554"	"Cc1cc(c(c(c1)C)N=c1cc2c3cc(c(cc3CCn2c(=O)n1CCNC(=O)N)OC)OC)C"	"CSOBIBXVIYAXFM-UHFFFAOYSA-N"	"InChI=1S/C26H31N5O4/c1-15-10-16(2)24(17(3)11-15)29-23-14-20-19-13-22(35-5)21(34-4)12-18(19)6-8-30(20)26(33)31(23)9-7-28-25(27)32/h10-14H,6-9H2,1-5H3,(H3,27,28,32)"	"yes"	""	""
"10492"	"envafolimab"	""	"Antibody"	"yes"	""	""	""	"387065574"	""	""	""	""	""	""	""	""	""	"envafolimab"	"Envida&reg;|KN-035|KN035"	""	""	""	"yes"	""	""
"8221"	"epacadostat"	""	"Synthetic organic"	""	""	""	""	"249565901"	"135564890"	""	""	"CHEMBL3545369"	""	""	""	""	"(3E)-3-[(3-bromo-4-fluoroanilino)-nitrosomethylidene]-4-[2-(sulfamoylamino)ethylamino]-1,2,5-oxadiazole"	"epacadostat"	"IDO inhibitor 1|INCB 24360|INCB-24360|INCB024360"	"O=N/C(=c\1/[nH]onc1NCCNS(=O)(=O)N)/Nc1ccc(c(c1)Br)F"	"YPBKTZBXSBLTDK-PKNBQFBNSA-N"	"InChI=1S/C11H13BrFN7O4S/c12-7-5-6(1-2-8(7)13)17-11(18-21)9-10(20-24-19-9)15-3-4-16-25(14,22)23/h1-2,5,16-17,19H,3-4H2,(H,15,20)(H2,14,22,23)/b11-9+"	"yes"	""	""
"11442"	"epcoritamab"	""	"Antibody"	"yes"	""	""	""	"440816811"	""	""	""	""	""	""	""	""	""	"epcoritamab"	"epcoritamab-bysp|Epkinly&reg;|GEN-3013|GEN3013|Tepkinly&reg;"	""	""	""	"yes"	""	""
"7176"	"epinastine"	""	"Synthetic organic"	"yes"	""	""	""	"178103751"	"3241"	""	""	"CHEMBL1106"	""	""	""	""	""	"epinastine"	"Elestat&reg;|epinastine hydrochloride"	"N=C1NCC2N1c1ccccc1Cc1c2cccc1"	"WHWZLSFABNNENI-UHFFFAOYSA-N"	"InChI=1S/C16H15N3/c17-16-18-10-15-13-7-3-1-5-11(13)9-12-6-2-4-8-14(12)19(15)16/h1-8,15H,9-10H2,(H2,17,18)"	"yes"	""	""
"8088"	"epratuzumab"	""	"Antibody"	""	""	""	""	"249565768"	""	""	""	""	""	""	""	""	""	"epratuzumab"	"90Y-DOTA-hLL2|90Y-epratuzumab tetraxetan|90Y-hLL2|AMG-412|IMMU-hLL2|LymphoCide&reg; (proposed proprietary name)"	""	""	""	"yes"	""	""
"9611"	"ER-27319"	""	"Synthetic organic"	""	""	""	""	"340590241"	"9799509"	""	""	"CHEMBL1375018"	""	""	""	""	"10-(3-aminopropyl)-3,4-dimethylacridin-9-one"	""	""	"NCCCn1c2ccccc2c(=O)c2c1c(C)c(C)cc2"	"CFPDEQBPNROZDC-UHFFFAOYSA-N"	"InChI=1S/C18H20N2O/c1-12-8-9-15-17(13(12)2)20(11-5-10-19)16-7-4-3-6-14(16)18(15)21/h3-4,6-9H,5,10-11,19H2,1-2H3"	"yes"	""	""
"9420"	"esflurbiprofen"	""	"Synthetic organic"	"yes"	""	""	""	"328083520"	"72099"	""	""	"CHEMBL435298"	""	""	""	""	"(2S)-2-(3-fluoro-4-phenylphenyl)propanoic acid"	"esflurbiprofen"	"(S)-flurbiprofen|BTS-24332|SFPP|TT-063"	"OC(=O)[C@H](c1ccc(c(c1)F)c1ccccc1)C"	"SYTBZMRGLBWNTM-JTQLQIEISA-N"	"InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m0/s1"	"yes"	""	""
"6789"	"etanercept"	""	"Peptide"	"yes"	""	""	""	"178103395"	""	""	""	"CHEMBL1201572"	""	""	""	""	""	"etanercept"	"Enbrel&reg;|Rhu Tnfr:Fc|TNFR-Fc|TNR 001"	""	""	""	"yes"	""	""
"13984"	"etigilimab"	""	"Antibody"	""	""	""	""	"518520611"	""	""	""	""	""	""	""	""	""	"etigilimab"	"OMP-313M32"	""	""	""	"yes"	""	""
"7185"	"etodolac"	""	"Synthetic organic"	"yes"	""	""	""	"178103760"	"3308"	""	""	"CHEMBL622"	""	""	""	""	"2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid"	"etodolac"	"AY-24236|Lodine&reg;"	"CCC1(OCCc2c1[nH]c1c2cccc1CC)CC(=O)O"	"NNYBQONXHNTVIJ-UHFFFAOYSA-N"	"InChI=1S/C17H21NO3/c1-3-11-6-5-7-12-13-8-9-21-17(4-2,10-14(19)20)16(13)18-15(11)12/h5-7,18H,3-4,8-10H2,1-2H3,(H,19,20)"	"yes"	""	""
"2896"	"etoricoxib"	""	"Synthetic organic"	"yes"	""	""	""	"178100245"	"123619"	""	""	"CHEMBL416146"	""	""	""	""	"5-chloro-2-(6-methylpyridin-3-yl)-3-(4-methylsulfonylphenyl)pyridine"	"etoricoxib"	"Arcoxia&reg;|MK 0663|MK-0663|MK0663"	"Clc1cnc(c(c1)c1ccc(cc1)S(=O)(=O)C)c1ccc(nc1)C"	"MNJVRJDLRVPLFE-UHFFFAOYSA-N"	"InChI=1S/C18H15ClN2O2S/c1-12-3-4-14(10-20-12)18-17(9-15(19)11-21-18)13-5-7-16(8-6-13)24(2,22)23/h3-11H,1-2H3"	"yes"	""	""
"9331"	"etrasimod"	""	"Synthetic organic"	"yes"	""	""	""	"318164850"	"44623998"	""	""	"CHEMBL3358920"	""	""	""	""	"2-[(3R)-7-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]acetic acid"	"etrasimod"	"APD-334|APD334|APD334-003|compound 4 [PMID: 25516790]|Velsipity&reg;"	"OC(=O)C[C@H]1CCc2c1[nH]c1c2cc(cc1)OCc1ccc(c(c1)C(F)(F)F)C1CCCC1"	"MVGWUTBTXDYMND-QGZVFWFLSA-N"	"InChI=1S/C26H26F3NO3/c27-26(28,29)22-11-15(5-8-19(22)16-3-1-2-4-16)14-33-18-7-10-23-21(13-18)20-9-6-17(12-24(31)32)25(20)30-23/h5,7-8,10-11,13,16-17,30H,1-4,6,9,12,14H2,(H,31,32)/t17-/m1/s1"	"yes"	""	""
"8407"	"etrolizumab"	""	"Antibody"	""	""	""	""	"252166617"	""	""	""	""	""	""	""	""	""	"etrolizumab"	"PRO145223|RG-7413|RG7413|rhuMAb Beta7"	""	""	""	"yes"	""	""
"5889"	"everolimus"	""	"Synthetic organic"	"yes"	""	""	""	"178102512"	"6442177"	""	""	"CHEMBL1908360"	""	""	""	""	""	"everolimus"	"Afinitor&reg;|Certican&reg;|RAD-001|RAD001|rapamycin, 42-O-(2-hydroxyethyl)-|Zortress&reg;"	"OCCO[C@@H]1CC[C@H](C[C@H]1OC)C[C@H]([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H](CC[C@H]2C)C[C@H](OC)/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C1)C)/C)O)OC)C)C)/C)C"	"HKVAMNSJSFKALM-GKUWKFKPSA-N"	"InChI=1S/C53H83NO14/c1-32-16-12-11-13-17-33(2)44(63-8)30-40-21-19-38(7)53(62,68-40)50(59)51(60)54-23-15-14-18-41(54)52(61)67-45(35(4)28-39-20-22-43(66-25-24-55)46(29-39)64-9)31-42(56)34(3)27-37(6)48(58)49(65-10)47(57)36(5)26-32/h11-13,16-17,27,32,34-36,38-41,43-46,48-49,55,58,62H,14-15,18-26,28-31H2,1-10H3/b13-11+,16-12+,33-17+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1"	"yes"	""	""
"9752"	"evobrutinib"	""	"Synthetic organic"	""	""	""	""	"354702225"	"71479709"	""	""	""	""	""	""	""	"1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]piperidin-1-yl]prop-2-en-1-one"	"evobrutinib"	"A250 [WO2012170976]|M-2951|M2951|MSC 2364447|MSC-2364447C|MSC2364447C"	"C=CC(=O)N1CCC(CC1)CNc1ncnc(c1c1ccc(cc1)Oc1ccccc1)N"	"QUIWHXQETADMGN-UHFFFAOYSA-N"	"InChI=1S/C25H27N5O2/c1-2-22(31)30-14-12-18(13-15-30)16-27-25-23(24(26)28-17-29-25)19-8-10-21(11-9-19)32-20-6-4-3-5-7-20/h2-11,17-18H,1,12-16H2,(H3,26,27,28,29)"	"yes"	""	""
"8489"	"example 131 [WO2009133348]"	""	"Synthetic organic"	""	""	""	""	"252166697"	"44468926"	""	""	""	""	""	""	""	"(2R)-N-[(2S)-1-[(6-aminopyridin-3-yl)methylamino]-3-(3,4-difluorophenyl)-1-oxopropan-2-yl]-1-ethylpyrrolidine-2-carboxamide"	""	""	"CCN1CCC[C@@H]1C(=O)N[C@H](C(=O)NCc1ccc(nc1)N)Cc1ccc(c(c1)F)F"	"ALLYUHIQZKTLFG-RBUKOAKNSA-N"	"InChI=1S/C22H27F2N5O2/c1-2-29-9-3-4-19(29)22(31)28-18(11-14-5-7-16(23)17(24)10-14)21(30)27-13-15-6-8-20(25)26-12-15/h5-8,10,12,18-19H,2-4,9,11,13H2,1H3,(H2,25,26)(H,27,30)(H,28,31)/t18-,19+/m0/s1"	"yes"	""	""
"10201"	"example 25 [WO2018228934]"	""	"Synthetic organic"	""	""	""	""	"381118911"	"137321170"	""	""	""	""	""	""	""	"(3'S)-1'-({3',5'-dihydro-2'H-spiro[cyclopropane-1,4'-pyrido[3,2-b][1,4]oxazepin]-8'-yl}carbonyl)-[1,3'-bipyrrolidin]-2-one"	""	""	"O=C1CCCN1[C@H]1CCN(C1)C(=O)c1cnc2c(c1)OCCC1(N2)CC1"	"UQONAEXHTGDOIH-AWEZNQCLSA-N"	"InChI=1S/C19H24N4O3/c24-16-2-1-7-23(16)14-3-8-22(12-14)18(25)13-10-15-17(20-11-13)21-19(4-5-19)6-9-26-15/h10-11,14H,1-9,12H2,(H,20,21)/t14-/m0/s1"	"yes"	""	""
"9555"	"example 36 [WO2016177845]"	""	"Synthetic organic"	""	""	""	""	"336446941"	"122670075"	""	""	""	""	""	""	""	"2-[5-[cyclopropylmethyl(1,2-dihydroacenaphthylen-5-yl)amino]-3-methoxypyridine-2-carbonyl]cyclopropane-1-carboxylic acid"	""	""	"COc1cc(cnc1C(=O)C1CC1C(=O)O)N(c1ccc2c3c1cccc3CC2)CC1CC1"	"FQHWQFIPEVBFKT-UHFFFAOYSA-N"	"InChI=1S/C27H26N2O4/c1-33-23-11-18(13-28-25(23)26(30)20-12-21(20)27(31)32)29(14-15-5-6-15)22-10-9-17-8-7-16-3-2-4-19(22)24(16)17/h2-4,9-11,13,15,20-21H,5-8,12,14H2,1H3,(H,31,32)"	"yes"	""	""
"10449"	"Example 4 [WO2017202275A1]"	""	"Synthetic organic"	""	""	""	""	"385612209"	"132184577"	""	""	""	""	""	""	""	"(2S)-1-{[4-({2-bromo-[1,1'-biphenyl]-3-yl}methoxy)-5-chloro-2-[(2-cyanopyridin-4-yl)methoxy]phenyl]methyl}piperidine-2-carboxylic acid"	""	""	"N#Cc1nccc(c1)COc1cc(OCc2cccc(c2Br)c2ccccc2)c(cc1CN1CCCC[C@H]1C(=O)O)Cl"	"YYAPLXNCTNGBJO-LJAQVGFWSA-N"	"InChI=1S/C33H29BrClN3O4/c34-32-24(9-6-10-27(32)23-7-2-1-3-8-23)21-42-31-17-30(41-20-22-12-13-37-26(15-22)18-36)25(16-28(31)35)19-38-14-5-4-11-29(38)33(39)40/h1-3,6-10,12-13,15-17,29H,4-5,11,14,19-21H2,(H,39,40)/t29-/m0/s1"	"yes"	""	""
"9255"	"F16357"	""	"Synthetic organic"	""	""	""	""	"315661330"	"19323337"	""	""	"CHEMBL559808"	""	""	""	""	"(E)-3-(2-chlorophenyl)-1-[4-[(4-fluorophenyl)methyl]piperazin-1-yl]prop-2-en-1-one"	""	"Compound 39 [PMID: 19791800]|Example 1 in WO2007147824"	"Fc1ccc(cc1)CN1CCN(CC1)C(=O)/C=C/c1ccccc1Cl"	"RMDYFILMTQCLCQ-JXMROGBWSA-N"	"InChI=1S/C20H20ClFN2O/c21-19-4-2-1-3-17(19)7-10-20(25)24-13-11-23(12-14-24)15-16-5-8-18(22)9-6-16/h1-10H,11-15H2/b10-7+"	"yes"	""	""
"10121"	"F215"	""	"Synthetic organic"	""	""	""	""	"381118831"	"132141153"	""	""	""	""	""	""	""	"3-[6-(3-chlorophenyl)hexanoyl]-1,3-oxazolidin-2-one"	""	""	"Clc1cccc(c1)CCCCCC(=O)N1CCOC1=O"	"XNQIFNVZSXXYRQ-UHFFFAOYSA-N"	"InChI=1S/C15H18ClNO3/c16-13-7-4-6-12(11-13)5-2-1-3-8-14(18)17-9-10-20-15(17)19/h4,6-7,11H,1-3,5,8-10H2"	"yes"	""	""
"14520"	"fangchinoline"	""	"Natural product"	""	""	""	""	""	"73481"	""	""	"CHEMBL504256"	""	""	""	""	""	""	"7-O-demethyltetrandrine|Hanfangichin B|Tetrandrine B"	"CN1CCC2=CC(=C3C=C2[C@@H]1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)C[C@H]6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC"	"IIQSJHUEZBTSAT-VMPREFPWSA-N"	"InChI=1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1"	"yes"	""	""
"5078"	"Fas ligand"	"Human"	"Peptide"	""	""	""	""	"178101771"	""	"P48023"	"ENSG00000117560"	""	""	""	""	""	""	""	"apoptosis antigen ligand|CD95L"	""	""	""	"yes"	""	""
"13455"	"felzartamab"	""	"Antibody"	""	""	""	""	"500839865"	""	""	""	""	""	""	""	""	""	"felzartamab"	"MOR-03087|MOR-202|MOR03087|MOR202"	""	""	""	"yes"	""	""
"9299"	"fenebrutinib"	""	"Synthetic organic"	""	""	""	""	"318164818"	"86567195"	""	""	""	""	""	""	""	"(S)-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one"	"fenebrutinib"	"Example 130 [US20140194408]|GDC-0853|GDC0853|RG-7845|RG7845"	"OCc1c(ccnc1N1CCn2c(C1=O)cc1c2CC(C1)(C)C)c1cc(Nc2ccc(cn2)N2CCN(C[C@@H]2C)C2COC2)c(=O)n(c1)C"	"WNEODWDFDXWOLU-QHCPKHFHSA-N"	"InChI=1S/C37H44N8O4/c1-23-18-42(27-21-49-22-27)9-10-43(23)26-5-6-33(39-17-26)40-30-13-25(19-41(4)35(30)47)28-7-8-38-34(29(28)20-46)45-12-11-44-31(36(45)48)14-24-15-37(2,3)16-32(24)44/h5-8,13-14,17,19,23,27,46H,9-12,15-16,18,20-22H2,1-4H3,(H,39,40)/t23-/m0/s1"	"yes"	""	""
"4820"	"fenoprofen"	""	"Synthetic organic"	"yes"	""	""	""	"178101522"	"3342"	""	""	"CHEMBL1297"	""	""	""	""	"2-(3-phenoxyphenyl)propanoic acid"	"fenoprofen"	"fenoprofen calcium|Nalfon&reg;"	"OC(=O)C(c1cccc(c1)Oc1ccccc1)C"	"RDJGLLICXDHJDY-UHFFFAOYSA-N"	"InChI=1S/C15H14O3/c1-11(15(16)17)12-6-5-9-14(10-12)18-13-7-3-2-4-8-13/h2-11H,1H3,(H,16,17)"	"yes"	""	""
"8995"	"fevipiprant"	""	"Synthetic organic"	""	""	""	""	"310264773"	"23582412"	""	""	"CHEMBL3137332"	""	""	""	""	"2-[2-methyl-1-[[4-methylsulfonyl-2-(trifluoromethyl)phenyl]methyl]pyrrolo[5,4-b]pyridin-3-yl]acetic acid"	"fevipiprant"	"NVP-QAW039|QAW039"	"OC(=O)Cc1c(C)n(c2c1cccn2)Cc1ccc(cc1C(F)(F)F)S(=O)(=O)C"	"GFPPXZDRVCSVNR-UHFFFAOYSA-N"	"InChI=1S/C19H17F3N2O4S/c1-11-15(9-17(25)26)14-4-3-7-23-18(14)24(11)10-12-5-6-13(29(2,27)28)8-16(12)19(20,21)22/h3-8H,9-10H2,1-2H3,(H,25,26)"	"yes"	""	""
"4819"	"fexofenadine"	""	"Synthetic organic"	"yes"	""	""	""	"178101521"	"3348"	""	""	"CHEMBL914"	""	""	""	""	"2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid"	"fexofenadine"	"Allegra&reg;|fexofenadine HCl"	"OC(=O)C(c1ccc(cc1)C(CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O)O)(C)C"	"RWTNPBWLLIMQHL-UHFFFAOYSA-N"	"InChI=1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)"	"yes"	""	""
"9281"	"fezakinumab"	""	"Antibody"	""	""	""	""	"318164800"	""	""	""	""	""	""	""	""	""	"fezakinumab"	"ILV-094"	""	""	""	"yes"	""	""
"14532"	"fianlimab"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"7913"	"filgotinib"	""	"Synthetic organic"	"yes"	""	""	""	"249565596"	"49831257"	""	""	"CHEMBL3301607"	""	""	""	""	"N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide"	"filgotinib"	"GLPG-0634|GLPG0634|Jyseleca&reg;"	"O=C(C1CC1)Nc1nc2n(n1)c(ccc2)c1ccc(cc1)CN1CCS(=O)(=O)CC1"	"RIJLVEAXPNLDTC-UHFFFAOYSA-N"	"InChI=1S/C21H23N5O3S/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25/h1-7,17H,8-14H2,(H,23,24,27)"	"yes"	""	""
"6968"	"filgrastim"	""	"Peptide"	"yes"	""	""	""	"178103548"	""	""	""	"CHEMBL1201567"	""	""	""	""	""	"filgrastim"	"Filcad&reg;|Imumax &reg;|R-METHUG-CSF"	""	""	""	"yes"	""	""
"8952"	"fimepinostat"	""	"Synthetic organic"	""	""	""	""	"310264733"	"54575456"	""	""	""	""	""	""	""	"N-hydroxy-2-[[2-(6-methoxypyridin-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl-methylamino]pyrimidine-5-carboxamide"	"fimepinostat"	"CUDC 907|CUDC-907|PI3K/HDAC Inhibitor centn"	"ONC(=O)c1cnc(nc1)N(Cc1cc2c(s1)c(nc(n2)c1ccc(nc1)OC)N1CCOCC1)C"	"JOWXJLIFIIOYMS-UHFFFAOYSA-N"	"InChI=1S/C23H24N8O4S/c1-30(23-25-11-15(12-26-23)22(32)29-33)13-16-9-17-19(36-16)21(31-5-7-35-8-6-31)28-20(27-17)14-3-4-18(34-2)24-10-14/h3-4,9-12,33H,5-8,13H2,1-2H3,(H,29,32)"	"yes"	""	""
"14355"	"fimsosertib"	""	"Synthetic organic"	""	""	""	""	"523352147"	"155905549"	""	""	"CHEMBL5174716"	""	""	""	""	"4-[3-[[2-amino-5-[2-(1-methylpiperidin-4-yl)-1,3-thiazol-5-yl]-3-pyridinyl]oxymethyl]phenyl]-2-methylbut-3-yn-2-ol"	"fimsosertib"	"compound 4 [PMID: 36621137]|PRJ1-3024|ZYF0033"	"CC(C)(C#CC1=CC=CC(=C1)COC2=C(N=CC(=C2)C3=CN=C(S3)C4CCN(CC4)C)N)O"	"BJNWUKRWOQERPQ-UHFFFAOYSA-N"	"InChI=1S/C26H30N4O2S/c1-26(2,31)10-7-18-5-4-6-19(13-18)17-32-22-14-21(15-28-24(22)27)23-16-29-25(33-23)20-8-11-30(3)12-9-20/h4-6,13-16,20,31H,8-9,11-12,17H2,1-3H3,(H2,27,28)"	"yes"	""	""
"2407"	"fingolimod"	""	"Synthetic organic"	"yes"	""	""	""	"135650261"	"107970"	""	""	"CHEMBL314854"	""	""	""	""	"2-amino-2-[2-(4-octylphenyl)ethyl]propane-1,3-diol"	"fingolimod"	"FTY-720|FTY720|Gilenya&reg;"	"CCCCCCCCc1ccc(cc1)CCC(CO)(CO)N"	"KKGQTZUTZRNORY-UHFFFAOYSA-N"	"InChI=1S/C19H33NO2/c1-2-3-4-5-6-7-8-17-9-11-18(12-10-17)13-14-19(20,15-21)16-22/h9-12,21-22H,2-8,13-16,20H2,1H3"	"yes"	""	""
"14401"	"finotonlimab"	""	"Antibody"	"yes"	""	""	""	"523352193"	""	""	""	""	""	""	""	""	""	"finotonlimab"	"SCT-I10A|Yasuhei&reg;"	""	""	""	"yes"	""	""
"8781"	"FIPI"	""	"Synthetic organic"	""	""	""	""	"252827439"	"16739265"	""	""	"CHEMBL398567"	""	""	""	""	"5-fluoro-N-[2-[4-(2-oxo-3H-benzimidazol-1-yl)piperidin-1-yl]ethyl]-1H-indole-2-carboxamide"	""	"compound 14 [PMID: 19136975]"	"Fc1ccc2c(c1)cc([nH]2)C(=O)NCCN1CCC(CC1)n1c(=O)[nH]c2c1cccc2"	"LHABRXRGDLASIH-UHFFFAOYSA-N"	"InChI=1S/C23H24FN5O2/c24-16-5-6-18-15(13-16)14-20(26-18)22(30)25-9-12-28-10-7-17(8-11-28)29-21-4-2-1-3-19(21)27-23(29)31/h1-6,13-14,17,26H,7-12H2,(H,25,30)(H,27,31)"	"yes"	""	""
"11486"	"firategrast"	""	"Synthetic organic"	""	""	""	""	"440816854"	"9935681"	""	""	"CHEMBL2104967"	""	""	""	""	""	"firategrast"	"SB-683699|SB683699"	"CCOCc1cc(OC)c(c(c1)OC)c1ccc(cc1)C[C@@H](C(=O)O)NC(=O)c1c(F)cccc1F"	"YLFZHHDVRSYTKT-NRFANRHFSA-N"	"InChI=1S/C27H27F2NO6/c1-4-36-15-17-13-22(34-2)24(23(14-17)35-3)18-10-8-16(9-11-18)12-21(27(32)33)30-26(31)25-19(28)6-5-7-20(25)29/h5-11,13-14,21H,4,12,15H2,1-3H3,(H,30,31)(H,32,33)/t21-/m0/s1"	"yes"	""	""
"7606"	"fludroxycortide"	""	"Synthetic organic"	"yes"	""	""	""	"223365941"	"15209"	""	""	"CHEMBL1201012"	""	""	""	""	""	"fludroxycortide"	"Cordran&reg;|flurandrenolide|flurandrenolone|Haelan&reg;"	"OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1C[C@@H](C1=CC(=O)CC[C@]21C)F)(C)C"	"POPFMWWJOGLOIF-XWCQMRHXSA-N"	"InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1"	"yes"	""	""
"2447"	"flufenamic acid"	""	"Synthetic organic"	"yes"	""	""	""	"135650269"	"3371"	""	""	"CHEMBL23588"	""	""	""	""	"2-[[3-(Trifluoromethyl)phenyl]amino]benzoic acid"	"flufenamic acid"	""	"OC(=O)c1ccccc1Nc1cccc(c1)C(F)(F)F"	"LPEPZBJOKDYZAD-UHFFFAOYSA-N"	"InChI=1S/C14H10F3NO2/c15-14(16,17)9-4-3-5-10(8-9)18-12-7-2-1-6-11(12)13(19)20/h1-8,18H,(H,19,20)"	"yes"	""	""
"7075"	"flumethasone pivalate"	""	"Synthetic organic"	"yes"	""	""	""	"178103654"	"443980"	""	""	"CHEMBL1200877"	""	""	""	""	"[2-[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] 2,2-dimethylpropanoate"	"flumetasone"	"Locorten&reg;"	"O=C1C=C[C@]2(C(=C1)[C@@H](F)C[C@@H]1[C@]2(F)[C@@H](O)C[C@]2([C@H]1C[C@H]([C@]2(O)C(=O)COC(=O)C(C)(C)C)C)C)C"	"JWRMHDSINXPDHB-OJAGFMMFSA-N"	"InChI=1S/C27H36F2O6/c1-14-9-16-17-11-19(28)18-10-15(30)7-8-24(18,5)26(17,29)20(31)12-25(16,6)27(14,34)21(32)13-35-22(33)23(2,3)4/h7-8,10,14,16-17,19-20,31,34H,9,11-13H2,1-6H3/t14-,16+,17+,19+,20+,24+,25+,26+,27+/m1/s1"	"yes"	""	""
"7076"	"flunisolide"	""	"Synthetic organic"	"yes"	""	""	""	"178103655"	"82153"	""	""	"CHEMBL1512"	""	""	""	""	""	"flunisolide"	"AeroBid&reg;|RS-3999"	"OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@H]2[C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)(C)C"	"XSFJVAJPIHIPKU-XWCQMRHXSA-N"	"InChI=1S/C24H31FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h5-7,13-14,16-17,19-20,26,28H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1"	"yes"	""	""
"7077"	"fluocinolone acetonide"	""	"Synthetic organic"	"yes"	""	""	""	"178103656"	"6215"	""	""	"CHEMBL989"	""	""	""	""	""	"fluocinolone acetonide"	"Capex&reg;|Iluvien&reg;|Synalar&reg;"	"OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C"	"FEBLZLNTKCEFIT-VSXGLTOVSA-N"	"InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1"	"yes"	""	""
"7078"	"fluocinonide"	""	"Synthetic organic"	"yes"	""	""	""	"178103657"	"9642"	""	""	"CHEMBL1501"	""	""	""	""	""	"fluocinonide"	"Fluonex&reg;|Lidex&reg;"	"CC(=O)OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C"	"WJOHZNCJWYWUJD-IUGZLZTKSA-N"	"InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1"	"yes"	""	""
"9987"	"fluorescent MIF ligand B"	""	"Synthetic organic"	""	""	"yes"	""	"374883874"	"134611891"	""	""	""	""	""	""	""	"N-{5-[({3',6'-dihydroxy-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-yl}carbamothioyl)amino]pentyl}-4-({2-[1-(3-fluoro-4-hydroxyphenyl)-1H-1,2,3-triazol-4-yl]quinolin-5-yl}oxy)butanamide"	""	""	"O=C(CCCOc1cccc2c1ccc(n2)c1nnn(c1)c1ccc(c(c1)F)O)NCCCCCNC(=S)Nc1ccc2c(c1)C(=O)OC12c2ccc(cc2Oc2c1ccc(c2)O)O"	"BMCSDEYJDALUKV-UHFFFAOYSA-N"	"InChI=1S/C47H40FN7O8S/c48-36-23-28(10-18-40(36)58)55-26-39(53-54-55)38-17-13-31-37(52-38)6-4-7-41(31)61-21-5-8-44(59)49-19-2-1-3-20-50-46(64)51-27-9-14-33-32(22-27)45(60)63-47(33)34-15-11-29(56)24-42(34)62-43-25-30(57)12-16-35(43)47/h4,6-7,9-18,22-26,56-58H,1-3,5,8,19-21H2,(H,49,59)(H2,50,51,64)"	"yes"	""	""
"7079"	"fluorometholone"	""	"Synthetic organic"	"yes"	""	""	""	"178103658"	"9878"	""	""	"CHEMBL1200600"	""	""	""	""	"(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one"	"fluorometholone"	"Flarex&reg;|FML&reg;"	"O=C1C=C[C@]2(C(=C1)[C@@H](C)C[C@@H]1[C@]2(F)[C@@H](O)C[C@]2([C@H]1CC[C@]2(O)C(=O)C)C)C"	"FAOZLTXFLGPHNG-KNAQIMQKSA-N"	"InChI=1S/C22H29FO4/c1-12-9-17-15-6-8-21(27,13(2)24)20(15,4)11-18(26)22(17,23)19(3)7-5-14(25)10-16(12)19/h5,7,10,12,15,17-18,26-27H,6,8-9,11H2,1-4H3/t12-,15-,17-,18-,19-,20-,21-,22-/m0/s1"	"yes"	""	""
"4194"	"flurbiprofen"	""	"Synthetic organic"	"yes"	""	""	""	"178101011"	"3394"	""	""	"CHEMBL563"	""	""	""	""	"2-(3-fluoro-4-phenylphenyl)propanoic acid"	"flurbiprofen"	"Ansaid&reg;|Froben&reg;"	"OC(=O)C(c1ccc(c(c1)F)c1ccccc1)C"	"SYTBZMRGLBWNTM-UHFFFAOYSA-N"	"InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)"	"yes"	""	""
"6699"	"fluticasone"	""	"Synthetic organic"	"yes"	""	""	""	"178103310"	"5311101"	""	""	"CHEMBL1201396"	""	""	""	""	"S-(fluoromethyl) (6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioate"	"fluticasone"	"Advair&reg;|Avamys&reg;|Flovent HFA&reg;|Veramyst&reg;"	"FCSC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F"	"MGNNYOODZCAHBA-GQKYHHCASA-N"	"InChI=1S/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1"	"yes"	""	""
"10892"	"fluticasone furoate"	""	"Synthetic organic"	"yes"	""	""	""	"405560333"	"9854489"	""	""	"CHEMBL1676"	""	""	""	""	"[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate"	"fluticasone furoate"	"Arnuity Ellipta|Avamys|FF|Flonase Sensimist|Veramyst"	"FCSC(=O)[C@@]1(OC(=O)c2ccco2)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F"	"XTULMSXFIHGYFS-VLSRWLAYSA-N"	"InChI=1S/C27H29F3O6S/c1-14-9-16-17-11-19(29)18-10-15(31)6-7-24(18,2)26(17,30)21(32)12-25(16,3)27(14,23(34)37-13-28)36-22(33)20-5-4-8-35-20/h4-8,10,14,16-17,19,21,32H,9,11-13H2,1-3H3/t14-,16+,17+,19+,21+,24+,25+,26+,27+/m1/s1"	"yes"	""	""
"7080"	"fluticasone propionate"	""	"Synthetic organic"	"yes"	""	""	""	"178103659"	"444036"	""	""	"CHEMBL1473"	""	""	""	""	"[(6S,8S,9R,10S,11S,13S,14S,16R,17R)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate"	"fluticasone"	"Advair Diskus&reg;|ArmonAir RespiClick<sup>TM</sup>|CCI-18781|Flovent&reg;"	"FCSC(=O)[C@@]1(OC(=O)CC)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)F)F"	"WMWTYOKRWGGJOA-CENSZEJFSA-N"	"InChI=1S/C25H31F3O5S/c1-5-20(31)33-25(21(32)34-12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15+,16+,18+,19+,22+,23+,24+,25+/m1/s1"	"yes"	""	""
"7189"	"fluvoxamine"	""	"Synthetic organic"	"yes"	""	""	""	"178103764"	"5324346"	""	""	"CHEMBL814"	""	""	""	""	"2-[(E)-[5-methoxy-1-[4-(trifluoromethyl)phenyl]pentylidene]amino]oxyethanamine"	"fluvoxamine"	"Luvox&reg;|U-23000"	"NCCO/N=C(/c1ccc(cc1)C(F)(F)F)\CCCCOC"	"CJOFXWAVKWHTFT-XSFVSMFZSA-N"	"InChI=1S/C15H21F3N2O2/c1-21-10-3-2-4-14(20-22-11-9-19)12-5-7-13(8-6-12)15(16,17)18/h5-8H,2-4,9-11,19H2,1H3/b20-14+"	"yes"	""	""
"12153"	"FLX475"	""	"Synthetic organic"	""	""	""	""	"472319275"	"134210715"	""	""	""	""	""	""	""	"2-[(3R)-3-[1-[1-[(1R)-1-(2,4-dichlorophenyl)ethyl]-3-(trifluoromethyl)pyrazolo[3,4-b]pyrazin-6-yl]azetidin-3-yl]piperidin-1-yl]ethanol"	""	"example 43 [WO2018022992A1]|FLX-475"	"C[C@H](c1c(cc(cc1)Cl)Cl)n1c2nc(cnc2c(n1)C(F)(F)F)N1CC(C1)[C@H]1CCCN(C1)CCO"	"AKSVALRPYDVQBS-CABCVRRESA-N"	"InChI=1S/C24H27Cl2F3N6O/c1-14(18-5-4-17(25)9-19(18)26)35-23-21(22(32-35)24(27,28)29)30-10-20(31-23)34-12-16(13-34)15-3-2-6-33(11-15)7-8-36/h4-5,9-10,14-16,36H,2-3,6-8,11-13H2,1H3/t14-,15+/m1/s1"	"yes"	""	""
"9847"	"fontolizumab"	""	"Antibody"	""	""	""	""	"363894141"	""	""	""	""	""	""	""	""	""	"fontolizumab"	"HuZAF"	""	""	""	"yes"	""	""
"3465"	"formoterol"	""	"Synthetic organic"	"yes"	""	""	""	"178100459"	"3410"	""	""	"CHEMBL1256786"	""	""	""	""	"N-[2-hydroxy-5-[1-hydroxy-2-[1-(4-methoxyphenyl)propan-2-ylamino]ethyl]phenyl]formamide"	"formoterol"	"BD-40A|CGP-25827A|Foradil&reg;|Oxeze/Oxis&reg;|YM-08316"	"O=CNc1cc(ccc1O)C(CNC(Cc1ccc(cc1)OC)C)O"	"BPZSYCZIITTYBL-UHFFFAOYSA-N"	"InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)"	"yes"	""	""
"10303"	"forsythoside B"	""	"Natural product"	""	""	""	""	"381744984"	"23928102"	""	""	""	""	""	""	""	"[(2R,3R,4R,5R,6R)-2-[[(2R,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-4-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate"	""	""	"OC[C@@]1(O)CO[C@H]([C@@H]1O)OC[C@H]1O[C@@H](OCCc2ccc(c(c2)O)O)[C@@H]([C@H]([C@@H]1OC(=O)/C=C/c1ccc(c(c1)O)O)O[C@@H]1O[C@@H](C)[C@@H]([C@H]([C@H]1O)O)O)O"	"JMBINOWGIHWPJI-UNSOMVRXSA-N"	"InChI=1S/C34H44O19/c1-15-24(41)25(42)26(43)32(50-15)53-29-27(44)31(47-9-8-17-3-6-19(37)21(39)11-17)51-22(12-48-33-30(45)34(46,13-35)14-49-33)28(29)52-23(40)7-4-16-2-5-18(36)20(38)10-16/h2-7,10-11,15,22,24-33,35-39,41-46H,8-9,12-14H2,1H3/b7-4+/t15-,22+,24-,25+,26+,27+,28+,29+,30-,31+,32-,33+,34+/m0/s1"	"yes"	""	""
"9649"	"fosdagrocorat"	""	"Synthetic organic"	""	""	""	""	"340590279"	"24872952"	""	""	"CHEMBL3137316"	""	""	""	""	"[(2R,4aS,10aR)-4a-benzyl-7-[(2-methylpyridin-3-yl)carbamoyl]-2-(trifluoromethyl)-1,3,4,9,10,10a-hexahydrophenanthren-2-yl] dihydrogen phosphate"	"fosdagrocorat"	"PF-04171327"	"O=C(c1ccc2c(c1)CC[C@H]1[C@]2(CC[C@](C1)(OP(=O)(O)O)C(F)(F)F)Cc1ccccc1)Nc1cccnc1C"	"BVXLAHSJXXSWFF-KEKPKEOLSA-N"	"InChI=1S/C29H30F3N2O5P/c1-19-25(8-5-15-33-19)34-26(35)22-10-12-24-21(16-22)9-11-23-18-28(29(30,31)32,39-40(36,37)38)14-13-27(23,24)17-20-6-3-2-4-7-20/h2-8,10,12,15-16,23H,9,11,13-14,17-18H2,1H3,(H,34,35)(H2,36,37,38)/t23-,27+,28-/m1/s1"	"yes"	""	""
"10637"	"fosifidancitinib"	""	"Synthetic organic"	""	""	""	""	"404859084"	"58071385"	""	""	""	""	""	""	""	"[5-[[2-(4-fluoro-3-methoxy-5-methylanilino)-5-methylpyrimidin-4-yl]amino]-2-oxo-1,3-benzoxazol-3-yl]methyl dihydrogen phosphate"	"fosifidancitinib"	""	"COc1cc(Nc2ncc(c(n2)Nc2ccc3c(c2)n(COP(=O)(O)O)c(=O)o3)C)cc(c1F)C"	"JTUBTEKGIDQZMZ-UHFFFAOYSA-N"	"InChI=1S/C21H21FN5O7P/c1-11-6-14(8-17(32-3)18(11)22)25-20-23-9-12(2)19(26-20)24-13-4-5-16-15(7-13)27(21(28)34-16)10-33-35(29,30)31/h4-9H,10H2,1-3H3,(H2,29,30,31)(H2,23,24,25,26)"	"yes"	""	""
"13806"	"fosizensertib"	""	"Synthetic organic"	""	""	""	""	"507750439"	"167466532"	""	""	""	""	""	""	""	"[(2S)-1-[[5-[2-[1-(difluoromethyl)pyrazol-4-yl]ethynyl]pyridine-3-carbonyl]-methylamino]-3-phenylpropan-2-yl] dihydrogen phosphate"	"fosizensertib"	"compound 19 [WO2023018643A1]"	"P(=O)(O[C@H](CN(C(=O)C=1C=NC=C(C1)C#CC=2C=NN(C2)C(F)F)C)CC3=CC=CC=C3)(O)O"	"AJSWMXIMACDPCV-FQEVSTJZSA-N"	"InChI=1S/C22H21F2N4O5P/c1-27(15-20(33-34(30,31)32)10-16-5-3-2-4-6-16)21(29)19-9-17(11-25-13-19)7-8-18-12-26-28(14-18)22(23)24/h2-6,9,11-14,20,22H,10,15H2,1H3,(H2,30,31,32)/t20-/m0/s1"	"yes"	""	""
"7796"	"fostamatinib"	""	"Synthetic organic"	"yes"	""	""	""	"223366127"	"11671467"	""	""	"CHEMBL2103830"	""	""	""	""	"[6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl]amino]-2,2-dimethyl-3-oxopyrido[2,3-e][1,4]oxazin-4-yl]methyl dihydrogen phosphate"	"fostamatinib"	"R 788|R-788|R7935788|Tavalisse&reg;|Tavlesse&reg;"	"COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)N(COP(=O)(O)O)C(=O)C(O3)(C)C)F)cc(c1OC)OC"	"GKDRMWXFWHEQQT-UHFFFAOYSA-N"	"InChI=1S/C23H26FN6O9P/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29)"	"yes"	""	""
"5191"	"FR122047"	""	"Synthetic organic"	""	""	""	""	"178101879"	"196841"	""	""	""	""	""	""	""	"1-{[bis(4-methoxyphenyl)-1,3-thiazol-2-yl]carbonyl}-4-methylpiperazine hydrochloride"	""	"FR 122047|FR 122047 hydrochloride|FR-122047"	"COc1ccc(cc1)c1sc(nc1c1ccc(cc1)OC)C(=O)N1CCN(CC1)C"	"UBHKJRYGKOSQDJ-UHFFFAOYSA-N"	"InChI=1S/C23H25N3O3S/c1-25-12-14-26(15-13-25)23(27)22-24-20(16-4-8-18(28-2)9-5-16)21(30-22)17-6-10-19(29-3)11-7-17/h4-11H,12-15H2,1-3H3"	"yes"	""	""
"12888"	"friluglanstat"	""	"Synthetic organic"	""	""	""	""	"485206009"	"71267445"	""	""	"CHEMBL3934885"	""	""	""	""	"N-(3-chloro-2-methylphenyl)-2-(methoxymethyl)-6-[[2-(trifluoromethyl)benzoyl]amino]-1H-benzimidazole-4-carboxamide"	""	"example 11 [US9216968B2]"	"ClC=1C(=C(C=CC1)NC(=O)C2=CC(=CC=3NC(=NC32)COC)NC(C4=C(C=CC=C4)C(F)(F)F)=O)C"	"ZPONWJXTHMDOSV-UHFFFAOYSA-N"	"InChI=1S/C25H20ClF3N4O3/c1-13-18(26)8-5-9-19(13)32-24(35)16-10-14(11-20-22(16)33-21(31-20)12-36-2)30-23(34)15-6-3-4-7-17(15)25(27,28)29/h3-11H,12H2,1-2H3,(H,30,34)(H,31,33)(H,32,35)"	"yes"	""	""
"5483"	"gabapentin"	""	"Synthetic organic"	"yes"	""	""	""	"178102130"	"3446"	""	""	"CHEMBL940"	""	""	""	""	"2-[1-(aminomethyl)cyclohexyl]acetic acid"	"gabapentin"	"CI 945|Go 3450|GOE 2450|GOE 3450|Neurontin&reg;"	"NCC1(CCCCC1)CC(=O)O"	"UGJMXCAKCUNAIE-UHFFFAOYSA-N"	"InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12)"	"yes"	""	""
"9848"	"Galapagos MAPKAPK5 inhibitor D"	""	"Synthetic organic"	""	""	""	""	"363894142"	"57589985"	""	""	""	""	""	""	""	"4-[8-[4-(4-tert-butylpiperazin-1-yl)anilino]-[1,2,4]triazolo[1,5-a]pyrazin-5-yl]furan-2-carboxamide"	""	"compound 183 [WO2007138072A2]"	"NC(=O)c1occ(c1)c1cnc(c2n1ncn2)Nc1ccc(cc1)N1CCN(CC1)C(C)(C)C"	"DLGZLIXYVSQGOX-UHFFFAOYSA-N"	"InChI=1S/C24H28N8O2/c1-24(2,3)31-10-8-30(9-11-31)18-6-4-17(5-7-18)29-22-23-27-15-28-32(23)19(13-26-22)16-12-20(21(25)33)34-14-16/h4-7,12-15H,8-11H2,1-3H3,(H2,25,33)(H,26,29)"	"yes"	""	""
"8967"	"galcanezumab"	""	"Antibody"	"yes"	""	""	""	"310264747"	""	""	""	""	""	""	""	""	""	"galcanezumab"	"clone III|Emgality&reg;|galcanezumab-gnlm|LY-2951742|LY2951742"	""	""	""	"yes"	""	""
"6603"	"galectin-1"	"Human"	"Peptide"	""	""	""	""	"178103216"	""	"P09382"	"ENSG00000100097"	""	""	""	""	""	""	""	"GBP"	""	""	""	"yes"	""	""
"6619"	"galectin-3"	"Human"	"Peptide"	""	""	""	""	"178103232"	""	"P17931"	"ENSG00000131981"	""	""	""	""	""	""	""	"galectin 3|GALIG|LGALS2|MAC-2"	""	""	""	"yes"	""	""
"6615"	"galectin-3 binding protein"	"Human"	"Peptide"	""	""	""	""	"178103228"	""	"Q08380"	"ENSG00000108679"	""	""	""	""	""	""	""	"L3 antigen|Mac-2-binding protein|MAC-2-BP"	""	""	""	"yes"	""	""
"9594"	"galectin 9"	"Human"	"Peptide"	""	""	""	""	"340590225"	""	"O00182"	"ENSG00000168961"	""	""	""	""	""	""	""	"Ecalectin|Gal-9|Tumor antigen HOM-HD-21"	""	""	""	"yes"	""	""
"12167"	"gamcemetinib"	""	"Synthetic organic"	""	""	""	""	"472319289"	"118936948"	""	""	""	""	""	""	""	""	""	"CC-99677|CC99677"	"CCOCc1cnc(nc1Oc1nc2c(cc1)c1c(cc2)sc2c1NC[C@H](NC2=O)C)Cl"	"PYOQIOLRFIRRSO-LLVKDONJSA-N"	"InChI=1S/C22H20ClN5O3S/c1-3-30-10-12-9-25-22(23)28-21(12)31-16-7-4-13-14(27-16)5-6-15-17(13)18-19(32-15)20(29)26-11(2)8-24-18/h4-7,9,11,24H,3,8,10H2,1-2H3,(H,26,29)/t11-/m1/s1"	"yes"	""	""
"14455"	"gamgertamig"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"gamgertamig"	"CM336|OM-336|OM336"	""	""	""	"yes"	""	""
"7909"	"gandotinib"	""	"Synthetic organic"	""	""	""	""	"249565592"	"46213929"	""	""	"CHEMBL2107823"	""	""	""	""	"3-[(4-chloro-2-fluorophenyl)methyl]-2-methyl-N-(5-methyl-1H-pyrazol-3-yl)-8-(morpholin-4-ylmethyl)imidazo[1,2-b]pyridazin-6-amine"	"gandotinib"	"LY-2784544|LY2784544"	"Clc1ccc(c(c1)F)Cc1c(C)nc2n1nc(Nc1n[nH]c(c1)C)cc2CN1CCOCC1"	"SQSZANZGUXWJEA-UHFFFAOYSA-N"	"InChI=1S/C23H25ClFN7O/c1-14-9-21(29-28-14)27-22-11-17(13-31-5-7-33-8-6-31)23-26-15(2)20(32(23)30-22)10-16-3-4-18(24)12-19(16)25/h3-4,9,11-12H,5-8,10,13H2,1-2H3,(H2,27,28,29,30)"	"yes"	""	""
"14465"	"garutadustat"	""	"Synthetic organic"	""	""	""	""	""	""	""	""	""	""	""	""	""	"tert-butyl 4-[6-[(6-cyano-3-pyridinyl)methylcarbamoyl]-5-hydroxy-1,7-naphthyridin-2-yl]piperazine-1-carboxylate"	""	"example 29 [WO2023072246]|ISM-5411|ISM5411"	"CC(C)(C)OC(=O)N1CCN(CC1)C2=NC3=CN=C(C(=C3C=C2)O)C(=O)NCC4=CN=C(C=C4)C#N"	"VXVKDBNSYJRFIQ-UHFFFAOYSA-N"	"InChI=1S/C25H27N7O4/c1-25(2,3)36-24(35)32-10-8-31(9-11-32)20-7-6-18-19(30-20)15-28-21(22(18)33)23(34)29-14-16-4-5-17(12-26)27-13-16/h4-7,13,15,33H,8-11,14H2,1-3H3,(H,29,34)"	"yes"	""	""
"6658"	"GB88"	""	"Synthetic organic"	""	""	""	""	"178103270"	"57330164"	""	""	"CHEMBL2431617"	""	""	""	""	"N-[(2S)-3-cyclohexyl-1-[[(2S,3R)-3-methyl-1-oxo-1-spiro[indene-1,4'-piperidine]-1'-ylpentan-2-yl]amino]-1-oxopropan-2-yl]-1,2-oxazole-5-carboxamide"	""	"GB 88|GB-88"	"CC[C@H]([C@@H](C(=O)N1CCC2(CC1)C=Cc1c2cccc1)NC(=O)[C@@H](NC(=O)c1ccno1)CC1CCCCC1)C"	"DCUDDCGUKZLQLN-ZEZZXZOMSA-N"	"InChI=1S/C32H42N4O4/c1-3-22(2)28(31(39)36-19-16-32(17-20-36)15-13-24-11-7-8-12-25(24)32)35-29(37)26(21-23-9-5-4-6-10-23)34-30(38)27-14-18-33-40-27/h7-8,11-15,18,22-23,26,28H,3-6,9-10,16-17,19-21H2,1-2H3,(H,34,38)(H,35,37)/t22-,26+,28+/m1/s1"	"yes"	""	""
"4934"	"G-CSF"	"Human"	"Peptide"	"yes"	""	""	""	"178101632"	""	"P09919"	"ENSG00000108342"	"CHEMBL2109128"	""	""	""	""	""	"lenograstim"	"Granocyte&reg;"	""	""	""	"yes"	""	""
"12318"	"GDC-0214"	""	"Synthetic organic"	""	""	""	""	"479821109"	"118522534"	""	""	"CHEMBL3964801"	""	""	""	""	"N-[3-[5-chloro-2-(difluoromethoxy)phenyl]-1-[2-[4-[2-cyanoethyl(methyl)amino]piperidin-1-yl]-2-oxoethyl]pyrazol-4-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide"	""	"GDC0214|iJak-381|RG-6151|RG6151"	"CN(CCC#N)C1CCN(CC1)C(=O)Cn1cc(c(n1)c1c(ccc(c1)Cl)OC(F)F)NC(=O)c1c2ncccn2nc1"	"ITNFPSJJBYFVEA-UHFFFAOYSA-N"	"InChI=1S/C28H28ClF2N9O3/c1-37(10-2-8-32)19-6-12-38(13-7-19)24(41)17-39-16-22(35-27(42)21-15-34-40-11-3-9-33-26(21)40)25(36-39)20-14-18(29)4-5-23(20)43-28(30)31/h3-5,9,11,14-16,19,28H,2,6-7,10,12-13,17H2,1H3,(H,35,42)"	"yes"	""	""
"9263"	"GDC-0834"	""	"Synthetic organic"	""	""	""	""	"315661338"	"25234918"	""	""	"CHEMBL2057915"	""	""	""	""	"N-[3-[6-[4-[(2R)-1,4-dimethyl-3-oxopiperazin-2-yl]anilino]-4-methyl-5-oxopyrazin-2-yl]-2-methylphenyl]-4,5,6,7-tetrahydro-1-benzothiophene-2-carboxamide"	""	"GDC 0834"	"CN1CCN(C(=O)[C@H]1c1ccc(cc1)Nc1nc(cn(c1=O)C)c1cccc(c1C)NC(=O)c1cc2c(s1)CCCC2)C"	"CDOOFZZILLRUQH-GDLZYMKVSA-N"	"InChI=1S/C33H36N6O3S/c1-20-24(9-7-10-25(20)36-31(40)28-18-22-8-5-6-11-27(22)43-28)26-19-39(4)33(42)30(35-26)34-23-14-12-21(13-15-23)29-32(41)38(3)17-16-37(29)2/h7,9-10,12-15,18-19,29H,5-6,8,11,16-17H2,1-4H3,(H,34,35)(H,36,40)/t29-/m1/s1"	"yes"	""	""
"12280"	"GDC-2394"	""	"Synthetic organic"	""	""	""	""	"473153868"	"135242204"	""	""	""	""	""	""	""	"1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[[(6S)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazin-3-yl]sulfonyl]urea"	""	"compound 20 [PMID: 36279149]|GDC2394"	"C1CCc2c(c3CCCc3cc12)NC(=O)NS(=O)(=O)c1cnn2c1OC[C@H](C2)NC"	"NDRARVKETDZHBS-AWEZNQCLSA-N"	"InChI=1S/C20H25N5O4S/c1-21-14-10-25-19(29-11-14)17(9-22-25)30(27,28)24-20(26)23-18-15-6-2-4-12(15)8-13-5-3-7-16(13)18/h8-9,14,21H,2-7,10-11H2,1H3,(H2,23,24,26)/t14-/m0/s1"	"yes"	""	""
"9540"	"gefapixant"	""	"Synthetic organic"	"yes"	""	""	""	"336446926"	"24764487"	""	""	""	""	""	""	""	"5-(2,4-diaminopyrimidin-5-yl)oxy-2-methoxy-4-propan-2-ylbenzenesulfonamide"	"gefapixant"	"AF-219|AF219|Lyfnua&reg;|MK7264|MK‐7264"	"COc1cc(C(C)C)c(cc1S(=O)(=O)N)Oc1cnc(nc1N)N"	"HLWURFKMDLAKOD-UHFFFAOYSA-N"	"InChI=1S/C14H19N5O4S/c1-7(2)8-4-10(22-3)12(24(17,20)21)5-9(8)23-11-6-18-14(16)19-13(11)15/h4-7H,1-3H3,(H2,17,20,21)(H4,15,16,18,19)"	"yes"	""	""
"6775"	"gemtuzumab ozogamicin"	""	"Antibody"	"yes"	""	""	""	"178103381"	""	""	""	""	""	""	""	""	""	"gemtuzumab ozogamicin"	"CDP 771|CMA 676|hP67.6-calicheamicin|Mylotarg&reg;|WAY-CMA 676"	""	""	""	"yes"	""	""
"7394"	"gevokizumab"	""	"Antibody"	""	""	""	""	"178103966"	""	""	""	""	""	""	""	""	""	"gevokizumab"	"XOMA 052|XOMA-052"	""	""	""	"yes"	""	""
"14500"	"GFH018"	""	"Synthetic organic"	""	""	""	""	""	"132246793"	""	""	"CHEMBL5518004"	""	""	""	""	"(E)-3-[6-[2-(6-methyl-2-pyridinyl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-[1,2,4]triazolo[1,5-a]pyridin-5-yl]prop-2-enamide"	""	"GFH-018"	"CC1=NC(=CC=C1)C2=NN3CCCC3=C2C4=C(N5C(=NC=N5)C=C4)/C=C/C(=O)N"	"FSQGWBXWGNWEAV-CMDGGOBGSA-N"	"InChI=1S/C21H19N7O/c1-13-4-2-5-15(25-13)21-20(17-6-3-11-27(17)26-21)14-7-10-19-23-12-24-28(19)16(14)8-9-18(22)29/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,22,29)/b9-8+"	"yes"	""	""
"9624"	"gimsilumab"	""	"Antibody"	""	""	""	""	"340590254"	""	""	""	""	""	""	""	""	""	"gimsilumab"	"MORAb-022"	""	""	""	"yes"	""	""
"9483"	"GlcC14C18"	""	"Synthetic organic"	""	""	""	""	"329968423"	"124221653"	""	""	""	""	""	""	""	"[(3S,6R)-3,5,6-trihydroxyoxan-2-yl]methyl 2-tridecylheptadecanoate"	""	"6-O-(2'(R,S)-tetradecyloctadecanoyl)-D-glucose"	"CCCCCCCCCCCCCCCC(C(=O)OCC1O[C@@H](O)C(C[C@@H]1O)O)CCCCCCCCCCCCC"	"HOINWSFARNFWIP-IGIMWDRYSA-N"	"InChI=1S/C36H70O6/c1-3-5-7-9-11-13-15-16-18-20-22-24-26-28-31(27-25-23-21-19-17-14-12-10-8-6-4-2)35(39)41-30-34-32(37)29-33(38)36(40)42-34/h31-34,36-38,40H,3-30H2,1-2H3/t31?,32-,33?,34?,36+/m0/s1"	"yes"	""	""
"2414"	"glibenclamide"	""	"Synthetic organic"	"yes"	""	""	""	"135650306"	"3488"	""	""	"CHEMBL472"	""	""	""	""	"5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide"	"glibenclamide"	"Amglidia&reg;|Diabeta&reg;|glyburide|Glynase&reg;"	"COc1ccc(cc1C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1)Cl"	"ZNNLBTZKUZBEKO-UHFFFAOYSA-N"	"InChI=1S/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)"	"yes"	""	""
"9896"	"GLP-2 analogue 10"	""	"Peptide"	""	""	""	""	"363894190"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"8417"	"GLPG0974"	""	"Synthetic organic"	""	""	""	""	"252166627"	"57520598"	""	""	""	""	""	""	""	"4-[[(2R)-1-(1-benzothiophene-3-carbonyl)-2-methylazetidine-2-carbonyl]-[(3-chlorophenyl)methyl]amino]butanoic acid"	""	"compound 99 [PMID 25380412]"	"OC(=O)CCCN(C(=O)[C@@]1(C)CCN1C(=O)c1csc2c1cccc2)Cc1cccc(c1)Cl"	"MPMKMQHJHDHPBE-RUZDIDTESA-N"	"InChI=1S/C25H25ClN2O4S/c1-25(11-13-28(25)23(31)20-16-33-21-9-3-2-8-19(20)21)24(32)27(12-5-10-22(29)30)15-17-6-4-7-18(26)14-17/h2-4,6-9,14,16H,5,10-13,15H2,1H3,(H,29,30)/t25-/m1/s1"	"yes"	""	""
"10171"	"GLPG1205"	""	"Synthetic organic"	""	""	""	""	"381118881"	"71616860"	""	""	""	""	""	""	""	"9-(2-cyclopropylethynyl)-2-[[(2S)-1,4-dioxan-2-yl]methoxy]-6,7-dihydropyrimido[6,1-a]isoquinolin-4-one"	""	"compound 122 [WO2013092791A1]|GLPG-1205"	"O=c1nc(OC[C@@H]2COCCO2)cc2n1CCc1c2ccc(c1)C#CC1CC1"	"IRBAWVGZNJIROV-SFHVURJKSA-N"	"InChI=1S/C22H22N2O4/c25-22-23-21(28-14-18-13-26-9-10-27-18)12-20-19-6-5-16(4-3-15-1-2-15)11-17(19)7-8-24(20)22/h5-6,11-12,15,18H,1-2,7-10,13-14H2/t18-/m0/s1"	"yes"	""	""
"12157"	"GLPG3970"	""	"Synthetic organic"	""	""	""	""	"472319279"	"146273261"	""	""	"CHEMBL4802154"	""	""	""	""	"8-methoxy-6-[7-(2-morpholin-4-ylethoxy)imidazo[1,2-a]pyridin-3-yl]-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1-one"	""	"compound 32 [PMID: 38552030]|compound 88 [WO2019238424A1]|GLPG-3970"	"COc1cc(cc2c1C(=O)N(CC2)CC(F)(F)F)c1cnc2n1ccc(c2)OCCN1CCOCC1"	"XASOHFCUIQARJT-UHFFFAOYSA-N"	"InChI=1S/C25H27F3N4O4/c1-34-21-13-18(12-17-2-4-31(16-25(26,27)28)24(33)23(17)21)20-15-29-22-14-19(3-5-32(20)22)36-11-8-30-6-9-35-10-7-30/h3,5,12-15H,2,4,6-11,16H2,1H3"	"yes"	""	""
"7459"	"glycopyrrolate"	""	"Synthetic organic"	"yes"	""	""	""	"187051762"	"3494"	""	""	"CHEMBL1201335"	""	""	""	""	"(1,1-dimethylpyrrolidin-1-ium-3-yl) 2-cyclopentyl-2-hydroxy-2-phenylacetate"	"glycopyrronium bromide"	"AHR-504|Qbrexza&reg (glycopyrronium cloth)|Robinul&reg;|Seebri Neohaler&reg;|Tovanor Breezhaler&reg;"	"O=C(C(c1ccccc1)(C1CCCC1)O)OC1CC[N+](C1)(C)C"	"ANGKOCUUWGHLCE-UHFFFAOYSA-N"	"InChI=1S/C19H28NO3/c1-20(2)13-12-17(14-20)23-18(21)19(22,16-10-6-7-11-16)15-8-4-3-5-9-15/h3-5,8-9,16-17,22H,6-7,10-14H2,1-2H3/q+1"	"yes"	""	""
"4942"	"GM-CSF"	"Human"	"Peptide"	""	""	""	""	"178101640"	""	"P04141"	"ENSG00000164400"	""	""	""	""	""	""	""	"colony-stimulating factor|CSF"	""	""	""	"yes"	""	""
"9660"	"GNE-3500"	""	"Synthetic organic"	""	""	""	""	"348353619"	"122379290"	""	""	""	""	""	""	""	"1-[4-[3-fluoro-4-[[(3S,6R)-3-methyl-1,1-dioxo-6-phenylthiazinan-2-yl]methyl]phenyl]piperazin-1-yl]ethanone"	""	""	"C[C@H]1CC[C@@H](S(=O)(=O)N1Cc1ccc(cc1F)N1CCN(CC1)C(=O)C)c1ccccc1"	"WLCIIQPUMOJJOF-MHECFPHRSA-N"	"InChI=1S/C24H30FN3O3S/c1-18-8-11-24(20-6-4-3-5-7-20)32(30,31)28(18)17-21-9-10-22(16-23(21)25)27-14-12-26(13-15-27)19(2)29/h3-7,9-10,16,18,24H,8,11-15,17H2,1-2H3/t18-,24+/m0/s1"	"yes"	""	""
"9995"	"GNE-4997"	""	"Synthetic organic"	""	""	""	""	"374883882"	"134611893"	""	""	""	""	""	""	""	""	""	"compound 28 [PMID: 25844760]|GNE 4997|GNE4997"	"O=C(c1n[nH]c2c1C[C@H]1[C@@](C2)(C1(F)F)C)Nc1cnn(c1)[C@H]([C@@H]1CCCCS1(=O)=O)c1ccccc1"	"JNRFIKALOWSUBG-CGCKEFBRSA-N"	"InChI=1S/C25H27F2N5O3S/c1-24-12-18-17(11-20(24)25(24,26)27)21(31-30-18)23(33)29-16-13-28-32(14-16)22(15-7-3-2-4-8-15)19-9-5-6-10-36(19,34)35/h2-4,7-8,13-14,19-20,22H,5-6,9-12H2,1H3,(H,29,33)(H,30,31)/t19-,20-,22-,24+/m0/s1"	"yes"	""	""
"13107"	"GNE684"	""	"Synthetic organic"	""	""	""	""	"491299889"	"138377384"	""	""	"CHEMBL5208359"	""	""	""	""	"(5S)-N-[(3S)-7-methoxy-1-methyl-2-oxo-4,5-dihydro-3H-pyrido[3,4-b]azepin-3-yl]-5-phenyl-6,7-dihydro-5H-pyrrolo[1,2-b][1,2,4]triazole-2-carboxamide"	""	"GNE-684"	"CN1C2=CN=C(C=C2CC[C@@H](C1=O)NC(=O)C3=NN4[C@@H](CCC4=N3)C5=CC=CC=C5)OC"	"JXFYROJRZJPKTQ-IRXDYDNUSA-N"	"InChI=1S/C23H24N6O3/c1-28-18-13-24-20(32-2)12-15(18)8-9-16(23(28)31)25-22(30)21-26-19-11-10-17(29(19)27-21)14-6-4-3-5-7-14/h3-7,12-13,16-17H,8-11H2,1-2H3,(H,25,30)/t16-,17-/m0/s1"	"yes"	""	""
"9548"	"GNF362"	""	"Synthetic organic"	""	""	""	""	"336446934"	"57999583"	""	""	""	""	""	""	""	"4-[4-[[(3R)-3-methyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl]-1H-pyrazol-5-yl]benzonitrile"	""	"example 71 [US20090306039]"	"N#Cc1ccc(cc1)c1n[nH]cc1CN1CCN([C@@H](C1)C)c1ccc(cn1)C(F)(F)F"	"VNTCGXMLDSKOKN-OAHLLOKOSA-N"	"InChI=1S/C22H21F3N6/c1-15-13-30(8-9-31(15)20-7-6-19(12-27-20)22(23,24)25)14-18-11-28-29-21(18)17-4-2-16(10-26)3-5-17/h2-7,11-12,15H,8-9,13-14H2,1H3,(H,28,29)/t15-/m1/s1"	"yes"	""	""
"6776"	"golimumab"	""	"Antibody"	"yes"	""	""	""	"178103382"	""	""	""	""	""	""	""	""	""	"golimumab"	"CNTO-148|CNTO148|Simponi&reg;"	""	""	""	"yes"	""	""
"10567"	"GPR15L"	"Human"	"Peptide"	""	""	""	""	"404859014"	"145996510"	"Q6UWK7"	"ENSG00000188373"	""	""	""	""	""	""	""	"antimicrobial peptide-57|colon-derived SUSD2 binding factor"	"NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)CCC(=O)N)CC(C)C)C)C(C)C)C(C)C)Cc1c[nH]c2c1cccc2)CC(C)C)CCCN=C(N)N)CCC(=O)O)CCC(=O)O)CC(C)C)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](O)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc2c[nH]c3c2cccc3)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)N)CCCN=C(N)N)CCCN=C(N)N)C)CCCCN)C)CO)CCCN=C(N)N)CCCN=C(N)N)CCCN=C(N)N)CC(C)C)C(=O)N[C@H]2CSSC[C@@H](C(=O)N[C@H](C(=O)N3[C@H](C(=O)N1)CCC3)CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]1N(C(=O)[C@@H](NC(=O)[C@H]3N(C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC2=O)Cc2c[nH]cn2)CCCN=C(N)N)C(C)C)CCC3)CO)CCC1)CC(=O)N)CO)[C@H](O)C)CC(=O)N)Cc1c[nH]cn1)C(C)C"	"MKYBCIBFBPPBKT-QSWODBGPSA-N"	""	"yes"	""	""
"10257"	"GR-389988"	""	"Synthetic organic"	""	""	""	""	"381744939"	"118009787"	""	""	"CHEMBL3673452"	""	""	""	""	""	""	"Ex. 3-15 [US9174986B2]|GR389988|GZ389988|GZ389988A"	"COc1cc(ccc1OCc1ccc(cc1)OC)Cn1c(N)nc2c1ncc(c2)c1cnn(c1)C"	"HVRWZFQFSQUILC-UHFFFAOYSA-N"	"InChI=1S/C26H26N6O3/c1-31-15-20(13-29-31)19-11-22-25(28-12-19)32(26(27)30-22)14-18-6-9-23(24(10-18)34-3)35-16-17-4-7-21(33-2)8-5-17/h4-13,15H,14,16H2,1-3H3,(H2,27,30)"	"yes"	""	""
"10118"	"Grp94 inhibitor 54"	""	"Synthetic organic"	""	""	""	""	"381118828"	"137321151"	""	""	""	""	""	""	""	"4'-(propan-2-yl)-4-{[(1r,4r)-4-hydroxycyclohexyl]amino}-[1,1'-biphenyl]-3-carboxamide"	""	""	"O[C@@H]1CC[C@H](CC1)Nc1ccc(cc1C(=O)N)c1ccc(cc1)C(C)C"	"JMGDXIHGWTVBMX-WGSAOQKQSA-N"	"InChI=1S/C22H28N2O2/c1-14(2)15-3-5-16(6-4-15)17-7-12-21(20(13-17)22(23)26)24-18-8-10-19(25)11-9-18/h3-7,12-14,18-19,24-25H,8-11H2,1-2H3,(H2,23,26)/t18-,19-"	"yes"	""	""
"10358"	"GSK065"	""	"Synthetic organic"	""	""	""	""	"384403639"	"121415134"	""	""	""	""	""	""	""	""	""	"GSK3335065|inhibitor C1 [PMID: 28604669]"	"OC(=O)CCc1noc2c1cc(Cl)c(c2)O[C@@H](c1ccccn1)C"	"WPAHVUADNLXSOM-SNVBAGLBSA-N"	"InChI=1S/C17H15ClN2O4/c1-10(13-4-2-3-7-19-13)23-16-9-15-11(8-12(16)18)14(20-24-15)5-6-17(21)22/h2-4,7-10H,5-6H2,1H3,(H,21,22)/t10-/m1/s1"	"yes"	""	""
"9388"	"GSK143"	""	"Synthetic organic"	""	""	""	""	"328083490"	"124037380"	""	""	""	""	""	""	""	"2-{[(3S,4S)-3-aminooxan-4-yl]amino}-4-[(4-methylphenyl)amino]pyrimidine-5-carboxamide"	""	"compound 20 [PMID: 21903390]"	"N[C@@H]1COCC[C@@H]1Nc1ncc(c(n1)Nc1ccc(cc1)C)C(=O)N"	"KBPYMFSSFLOJPH-KGLIPLIRSA-N"	"InChI=1S/C17H22N6O2/c1-10-2-4-11(5-3-10)21-16-12(15(19)24)8-20-17(23-16)22-14-6-7-25-9-13(14)18/h2-5,8,13-14H,6-7,9,18H2,1H3,(H2,19,24)(H2,20,21,22,23)/t13-,14+/m1/s1"	"yes"	""	""
"10504"	"GSK1482160"	""	"Synthetic organic"	""	""	""	""	"387065586"	"23649427"	""	""	"CHEMBL1222883"	""	""	""	""	""	""	"compound 1b [PMID: 31525963]|compound 31 [PMID: 20673717]|GSK-1482160"	"CN1C(=O)CC[C@H]1C(=O)NCc1cccc(c1Cl)C(F)(F)F"	"BJEMSIVBBUBXMZ-JTQLQIEISA-N"	"InChI=1S/C14H14ClF3N2O2/c1-20-10(5-6-11(20)21)13(22)19-7-8-3-2-4-9(12(8)15)14(16,17)18/h2-4,10H,5-7H2,1H3,(H,19,22)/t10-/m0/s1"	"yes"	""	""
"10416"	"GSK2239633A"	""	"Synthetic organic"	""	""	""	""	"385612176"	"46861584"	""	""	"CHEMBL2018969"	""	""	""	""	"N-[[3-[[3-[(5-chlorothiophen-2-yl)sulfonylamino]-4-methoxyindazol-1-yl]methyl]phenyl]methyl]-2-hydroxy-2-methylpropanamide"	""	"compound 6 [PMID: 23409871]|GSK-2239633A"	"COc1cccc2c1c(nn2Cc1cccc(c1)CNC(=O)C(O)(C)C)NS(=O)(=O)c1ccc(s1)Cl"	"YTEVTHHGQMUPHC-UHFFFAOYSA-N"	"InChI=1S/C24H25ClN4O5S2/c1-24(2,31)23(30)26-13-15-6-4-7-16(12-15)14-29-17-8-5-9-18(34-3)21(17)22(27-29)28-36(32,33)20-11-10-19(25)35-20/h4-12,31H,13-14H2,1-3H3,(H,26,30)(H,27,28)"	"yes"	""	""
"9254"	"GSK2245035"	""	"Synthetic organic"	""	""	""	""	"315661329"	"44623937"	""	""	""	""	""	""	""	"6-amino-2-[(2S)-pentan-2-yloxy]-9-[5-(piperidin-1-yl)pentyl]-8,9-dihydro-7H-purin-8-one"	""	"compound 32 [PMID: 26861551]"	"CCC[C@@H](Oc1nc(N)c2c(n1)n(CCCCCN1CCCCC1)c(=O)[nH]2)C"	"LFMPVTVPXHNXOT-HNNXBMFYSA-N"	"InChI=1S/C20H34N6O2/c1-3-10-15(2)28-19-23-17(21)16-18(24-19)26(20(27)22-16)14-9-5-8-13-25-11-6-4-7-12-25/h15H,3-14H2,1-2H3,(H,22,27)(H2,21,23,24)/t15-/m0/s1"	"yes"	""	""
"9718"	"GSK2256294"	""	"Synthetic organic"	""	""	""	""	"348353677"	"59448236"	""	""	"CHEMBL3818875"	""	""	""	""	"(1R,3S)-N-(4-cyano-2-(trifluoromethyl)benzyl)-3-((4-methyl-6-(methylamino)-1,3,5-triazin-2-yl)amino)cyclohexane-1-carboxamide"	""	"GSK-2256294|GSK-2256294A|GSK2256294A"	"CNc1nc(N[C@H]2CCC[C@H](C2)C(=O)NCc2ccc(cc2C(F)(F)F)C#N)nc(n1)C"	"LQHDJQIMETZMPH-ZBFHGGJFSA-N"	"InChI=1S/C21H24F3N7O/c1-12-28-19(26-2)31-20(29-12)30-16-5-3-4-14(9-16)18(32)27-11-15-7-6-13(10-25)8-17(15)21(22,23)24/h6-8,14,16H,3-5,9,11H2,1-2H3,(H,27,32)(H2,26,28,29,30,31)/t14-,16+/m1/s1"	"yes"	""	""
"10633"	"GSK2292767"	""	"Synthetic organic"	""	""	""	""	"404859080"	"49783923"	""	""	""	""	""	""	""	"N-[5-[4-[5-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]-1,3-oxazol-2-yl]-1H-indazol-6-yl]-2-methoxypyridin-3-yl]methanesulfonamide"	""	"compound 2 [PMID: 30532965]|compound 3 [PMID: 26301626]|GSK-2292767"	"COc1ncc(cc1NS(=O)(=O)C)c1cc(c2ncc(o2)CN2C[C@H](C)O[C@@H](C2)C)c2c(c1)[nH]nc2"	"NLUPPCTVKHDVIQ-GASCZTMLSA-N"	"InChI=1S/C24H28N6O5S/c1-14-11-30(12-15(2)34-14)13-18-9-26-23(35-18)19-5-16(6-21-20(19)10-27-28-21)17-7-22(29-36(4,31)32)24(33-3)25-8-17/h5-10,14-15,29H,11-13H2,1-4H3,(H,27,28)/t14-,15+"	"yes"	""	""
"10108"	"GSK2646264"	""	"Synthetic organic"	""	""	""	""	"381118818"	"137321148"	""	""	""	""	""	""	""	"7-{2-methoxy-6-[(4-methylpyridin-2-yl)methoxy]phenyl}-2,3,4,5,5a,9a-hexahydro-1H-3-benzazepine"	""	"compound 44 [PMID: 30249354]"	"COc1cccc(c1C1=CC2C(C=C1)CCNCC2)OCc1nccc(c1)C"	"CQLSAYKHANAIMX-UHFFFAOYSA-N"	"InChI=1S/C24H28N2O2/c1-17-8-13-26-21(14-17)16-28-23-5-3-4-22(27-2)24(23)20-7-6-18-9-11-25-12-10-19(18)15-20/h3-8,13-15,18-19,25H,9-12,16H2,1-2H3"	"yes"	""	""
"9116"	"GSK2879552"	""	"Synthetic organic"	""	""	""	""	"315661201"	"66571643"	""	""	""	""	""	""	""	"4-[[4-[[[(1R,2S)-2-phenylcyclopropyl]amino]methyl]piperidin-1-yl]methyl]benzoic acid"	""	"Example 26 [WO2012135113]|GSK-2879552"	"OC(=O)c1ccc(cc1)CN1CCC(CC1)CN[C@@H]1C[C@H]1c1ccccc1"	"LRULVYSBRWUVGR-FCHUYYIVSA-N"	"InChI=1S/C23H28N2O2/c26-23(27)20-8-6-18(7-9-20)16-25-12-10-17(11-13-25)15-24-22-14-21(22)19-4-2-1-3-5-19/h1-9,17,21-22,24H,10-16H2,(H,26,27)/t21-,22+/m0/s1"	"yes"	""	""
"9661"	"GSK2981278"	""	"Synthetic organic"	""	""	""	""	"348353620"	"89875987"	""	""	""	""	""	""	""	"N-(4-ethylphenyl)-3-(hydroxymethyl)-N-(2-methylpropyl)-4-(oxan-4-ylmethoxy)benzenesulfonamide"	""	""	"OCc1cc(ccc1OCC1CCOCC1)S(=O)(=O)N(c1ccc(cc1)CC)CC(C)C"	"LZLBRISQTJVZNP-UHFFFAOYSA-N"	"InChI=1S/C25H35NO5S/c1-4-20-5-7-23(8-6-20)26(16-19(2)3)32(28,29)24-9-10-25(22(15-24)17-27)31-18-21-11-13-30-14-12-21/h5-10,15,19,21,27H,4,11-14,16-18H2,1-3H3"	"yes"	""	""
"9554"	"GSK2982772"	""	"Synthetic organic"	""	""	""	""	"336446940"	"77108121"	""	""	""	""	""	""	""	"5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide"	""	"compound 5 [PMID: 28151659]"	"O=C(c1n[nH]c(n1)Cc1ccccc1)N[C@H]1COc2c(N(C1=O)C)cccc2"	"LYPAFUINURXJSG-AWEZNQCLSA-N"	"InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(23-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24)/t14-/m0/s1"	"yes"	""	""
"9623"	"GSK3050002"	""	"Antibody"	""	""	""	""	"340590253"	""	""	""	""	""	""	""	""	""	""	"E6071|KANAb071"	""	""	""	"yes"	""	""
"8240"	"GSK343"	""	"Synthetic organic"	""	""	""	""	"249565920"	"71268957"	""	""	"CHEMBL2204995"	""	""	""	""	"N-[(6-methyl-2-oxo-4-propyl-1,2-dihydropyridin-3-yl)methyl]-6-[2-(4-methylpiperazin-1-yl)pyridin-4-yl]-1-(propan-2-yl)-1H-indazole-4-carboxamide"	""	"compound 6 [PMID 24900432]|GSK 343"	"CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(cc2c1cnn2C(C)C)c1ccnc(c1)N1CCN(CC1)C"	"ULNXAWLQFZMIHX-UHFFFAOYSA-N"	"InChI=1S/C31H39N7O2/c1-6-7-23-14-21(4)35-31(40)26(23)18-33-30(39)25-15-24(16-28-27(25)19-34-38(28)20(2)3)22-8-9-32-29(17-22)37-12-10-36(5)11-13-37/h8-9,14-17,19-20H,6-7,10-13,18H2,1-5H3,(H,33,39)(H,35,40)"	"yes"	""	""
"11274"	"GSK'547"	""	"Synthetic organic"	""	""	""	""	"434321709"	"134521814"	""	""	""	""	""	""	""	"6-[4-[(3S)-3-(3,5-difluorophenyl)-3,4-dihydropyrazole-2-carbonyl]piperidin-1-yl]pyrimidine-4-carbonitrile"	""	"example 6 [WO2020044206A1]|GSK-547|GSK547"	"N#Cc1ncnc(c1)N1CCC(CC1)C(=O)N1N=CC[C@H]1c1cc(F)cc(c1)F"	"SJVGFKBLUYAEOK-SFHVURJKSA-N"	"InChI=1S/C20H18F2N6O/c21-15-7-14(8-16(22)9-15)18-1-4-26-28(18)20(29)13-2-5-27(6-3-13)19-10-17(11-23)24-12-25-19/h4,7-10,12-13,18H,1-3,5-6H2/t18-/m0/s1"	"yes"	""	""
"9134"	"GSK583"	""	"Synthetic organic"	""	""	""	""	"315661219"	"67469084"	""	""	""	""	""	""	""	"N-(5-fluoro-1H-indazol-3-yl)-6-(2-methylpropane-2-sulfonyl)quinolin-4-amine"	""	"GSK'583"	"Fc1ccc2c(c1)c(n[nH]2)Nc1ccnc2c1cc(cc2)S(=O)(=O)C(C)(C)C"	"XLOGLWKOHPIJLV-UHFFFAOYSA-N"	"InChI=1S/C20H19FN4O2S/c1-20(2,3)28(26,27)13-5-7-16-14(11-13)17(8-9-22-16)23-19-15-10-12(21)4-6-18(15)24-25-19/h4-11H,1-3H3,(H2,22,23,24,25)"	"yes"	""	""
"10088"	"GSK-7975A"	""	"Synthetic organic"	""	""	""	""	"381118798"	"59547990"	""	""	""	""	""	""	""	"2,6-difluoro-N-[1-[[4-hydroxy-2-(trifluoromethyl)phenyl]methyl]pyrazol-3-yl]benzamide"	""	"example 36 [US20120053150A1]|GSK7975A"	"Oc1ccc(c(c1)C(F)(F)F)Cn1ccc(n1)NC(=O)c1c(F)cccc1F"	"CPYTVBALBFSXSH-UHFFFAOYSA-N"	"InChI=1S/C18H12F5N3O2/c19-13-2-1-3-14(20)16(13)17(28)24-15-6-7-26(25-15)9-10-4-5-11(27)8-12(10)18(21,22)23/h1-8,27H,9H2,(H,24,25,28)"	"yes"	""	""
"10343"	"GSK8612"	""	"Synthetic organic"	""	""	""	""	"381745024"	"137553174"	""	""	""	""	""	""	""	"4-{[(5-bromo-2-{[3-methyl-1-(2,2,2-trifluoroethyl)-1H-pyrazol-4-yl]amino}pyrimidin-4-yl)amino]methyl}benzene-1-sulfonamide"	""	""	"Brc1cnc(nc1NCc1ccc(cc1)S(=O)(=O)N)Nc1cn(nc1C)CC(F)(F)F"	"FFPHMUIGESPOTK-UHFFFAOYSA-N"	"InChI=1S/C17H17BrF3N7O2S/c1-10-14(8-28(27-10)9-17(19,20)21)25-16-24-7-13(18)15(26-16)23-6-11-2-4-12(5-3-11)31(22,29)30/h2-5,7-8H,6,9H2,1H3,(H2,22,29,30)(H2,23,24,25,26)"	"yes"	""	""
"9653"	"GSK866"	""	"Synthetic organic"	""	""	""	""	"340590283"	"25058139"	""	""	""	""	""	""	""	"5-amino-N-[(2S)-2-[[(2,6-dichlorobenzoyl)-ethylamino]methyl]-3,3,3-trifluoro-2-hydroxypropyl]-1-(4-fluorophenyl)pyrazole-4-carboxamide"	""	""	"CCN(C(=O)c1c(Cl)cccc1Cl)C[C@](C(F)(F)F)(CNC(=O)c1cnn(c1N)c1ccc(cc1)F)O"	"LKQMULLPLYLIGW-QFIPXVFZSA-N"	"InChI=1S/C23H21Cl2F4N5O3/c1-2-33(21(36)18-16(24)4-3-5-17(18)25)12-22(37,23(27,28)29)11-31-20(35)15-10-32-34(19(15)30)14-8-6-13(26)7-9-14/h3-10,37H,2,11-12,30H2,1H3,(H,31,35)/t22-/m0/s1"	"yes"	""	""
"10132"	"GSK963"	""	"Synthetic organic"	""	""	""	""	"381118842"	"122703613"	""	""	""	""	""	""	""	"2,2-dimethyl-1-[(3S)-3-phenyl-3,4-dihydropyrazol-2-yl]propan-1-one"	""	"GSK'963|GSK′963A"	"O=C(C(C)(C)C)N1N=CC[C@H]1c1ccccc1"	"NJQVSLWJBLPTMD-LBPRGKRZSA-N"	"InChI=1S/C14H18N2O/c1-14(2,3)13(17)16-12(9-10-15-16)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3/t12-/m0/s1"	"yes"	""	""
"7027"	"GSK-J1"	""	"Synthetic organic"	""	""	""	""	"178103606"	"56963315"	""	""	"CHEMBL3188597"	""	""	""	""	"3-{[2-(pyridin-2-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoic acid"	""	""	"OC(=O)CCNc1nc(nc(c1)N1CCc2ccccc2CC1)c1ccccn1"	"AVZCPICCWKMZDT-UHFFFAOYSA-N"	"InChI=1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26)"	"yes"	""	""
"8979"	"GSK-J4"	""	"Synthetic organic"	""	""	""	""	"310264759"	"71729975"	""	""	"CHEMBL3183531"	""	""	""	""	"ethyl 3-{[2-(pyridin-2-yl)-6-(2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)pyrimidin-4-yl]amino}propanoate"	""	"GSK J4|GSKJ4"	"CCOC(=O)CCNc1cc(nc(n1)c1ccccn1)N1CCc2c(CC1)cccc2"	"WBKCKEHGXNWYMO-UHFFFAOYSA-N"	"InChI=1S/C24H27N5O2/c1-2-31-23(30)10-14-26-21-17-22(28-24(27-21)20-9-5-6-13-25-20)29-15-11-18-7-3-4-8-19(18)12-16-29/h3-9,13,17H,2,10-12,14-16H2,1H3,(H,26,27,28)"	"yes"	""	""
"13889"	"gumokimab"	""	"Antibody"	""	""	""	""	"513757574"	""	""	""	""	""	""	""	""	""	"gumokimab"	"AK-111|AK111"	""	""	""	"yes"	""	""
"10000"	"gusacitinib"	""	"Synthetic organic"	""	""	""	""	"374883887"	"71269142"	""	""	""	""	""	""	""	""	"gusacitinib"	"ASN-002|ASN002|example 189 [WO2013028818A1]"	"N#CCC1CCN(CC1)c1nc(Nc2ccc(cc2)N2CCC(CC2)O)c2c(n1)cn[nH]c2=O"	"NLFLXLJXEIUQDL-UHFFFAOYSA-N"	"InChI=1S/C24H28N8O2/c25-10-5-16-6-11-32(12-7-16)24-28-20-15-26-30-23(34)21(20)22(29-24)27-17-1-3-18(4-2-17)31-13-8-19(33)9-14-31/h1-4,15-16,19,33H,5-9,11-14H2,(H,30,34)(H,27,28,29)"	"yes"	""	""
"7998"	"guselkumab"	""	"Antibody"	"yes"	""	""	""	"249565678"	""	""	""	""	""	""	""	""	""	"guselkumab"	"CNTO-1959|Tremfya&reg;"	""	""	""	"yes"	""	""
"9849"	"GW274150"	""	"Synthetic organic"	""	""	""	""	"363894143"	"9797017"	""	""	"CHEMBL114551"	""	""	""	""	"(2S)-2-amino-4-[2-(1-aminoethylideneamino)ethylsulfanyl]butanoic acid"	""	"[2-[(1-iminoethyl) amino]ethyl]-L-homocysteine|GW-274150"	"CC(=NCCSCC[C@@H](C(=O)O)N)N"	"MOLOJNHYNHBPCW-ZETCQYMHSA-N"	"InChI=1S/C8H17N3O2S/c1-6(9)11-3-5-14-4-2-7(10)8(12)13/h7H,2-5,10H2,1H3,(H2,9,11)(H,12,13)/t7-/m0/s1"	"yes"	""	""
"2754"	"GW3965"	""	"Synthetic organic"	""	""	""	""	"135650333"	"447905"	""	""	"CHEMBL59030"	""	""	""	""	"2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid"	""	"C473027|GW 3965|GW-3965"	"OC(=O)Cc1cccc(c1)OCCCN(CC(c1ccccc1)c1ccccc1)Cc1cccc(c1Cl)C(F)(F)F"	"NAXSRXHZFIBFMI-UHFFFAOYSA-N"	"InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40)"	"yes"	""	""
"9850"	"GW406381"	""	"Synthetic organic"	""	""	""	""	"363894144"	"9832687"	""	""	"CHEMBL364804"	""	""	""	""	"2-(4-ethoxyphenyl)-3-(4-methylsulfonylphenyl)pyrazolo[5,1-f]pyridazine"	""	"compound 8 [PMID: 15454242]|GW-406381"	"CCOc1ccc(cc1)c1nn2c(c1c1ccc(cc1)S(=O)(=O)C)cccn2"	"NXMZBNYLCVTRGB-UHFFFAOYSA-N"	"InChI=1S/C21H19N3O3S/c1-3-27-17-10-6-16(7-11-17)21-20(19-5-4-14-22-24(19)23-21)15-8-12-18(13-9-15)28(2,25)26/h4-14H,3H2,1-2H3"	"yes"	""	""
"1953"	"GW 627368"	""	"Synthetic organic"	""	""	""	""	"135650338"	"5312130"	""	""	"CHEMBL1628527"	""	""	""	""	"2-[4-(4,9-diethoxy-3-oxo-1H-benzo[f]isoindol-2-yl)phenyl]-N-phenylsulfonylacetamide"	""	"GW-627368|GW627368|saccharic acid"	"CCOc1c2C(=O)N(Cc2c(c2c1cccc2)OCC)c1ccc(cc1)CC(=O)NS(=O)(=O)c1ccccc1"	"XREWXJVMYAXCJV-UHFFFAOYSA-N"	"InChI=1S/C30H28N2O6S/c1-3-37-28-23-12-8-9-13-24(23)29(38-4-2)27-25(28)19-32(30(27)34)21-16-14-20(15-17-21)18-26(33)31-39(35,36)22-10-6-5-7-11-22/h5-17H,3-4,18-19H2,1-2H3,(H,31,33)"	"yes"	""	""
"9680"	"GW766994"	""	"Synthetic organic"	""	""	""	""	"348353639"	"9825034"	""	""	"CHEMBL2178574"	""	""	""	""	"4-[[[(2R)-4-[(3,4-dichlorophenyl)methyl]morpholin-2-yl]methylcarbamoylamino]methyl]benzamide"	""	"GSK766994|GW-766994"	"O=C(NCc1ccc(cc1)C(=O)N)NC[C@H]1OCCN(C1)Cc1ccc(c(c1)Cl)Cl"	"GPLUUMAKBFSDIE-QGZVFWFLSA-N"	"InChI=1S/C21H24Cl2N4O3/c22-18-6-3-15(9-19(18)23)12-27-7-8-30-17(13-27)11-26-21(29)25-10-14-1-4-16(5-2-14)20(24)28/h1-6,9,17H,7-8,10-13H2,(H2,24,28)(H2,25,26,29)/t17-/m1/s1"	"yes"	""	""
"9808"	"GYY4137 parent molecule"	""	"Synthetic organic"	""	""	""	""	"354702280"	"53393943"	""	""	""	""	""	""	""	"(4-methoxyphenyl)-morpholin-4-yl-sulfanyl-sulfanylidene-$l^{5}-phosphane"	""	"GYY4137"	"COc1ccc(cc1)P(=S)(N1CCOCC1)S"	"QDSAKNAFJWRQIV-UHFFFAOYSA-N"	"InChI=1S/C11H16NO2PS2/c1-13-10-2-4-11(5-3-10)15(16,17)12-6-8-14-9-7-12/h2-5H,6-9H2,1H3,(H,16,17)"	"yes"	""	""
"10122"	"H-151"	""	"Synthetic organic"	""	""	""	""	"381118832"	"7616033"	""	""	""	""	""	""	""	"3-(4-ethylphenyl)-1-(1H-indol-3-yl)urea"	""	"H 151|H151"	"CCc1ccc(cc1)NC(=O)Nc1c[nH]c2c1cccc2"	"UJZDIKVQFMCLBE-UHFFFAOYSA-N"	"InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21)"	"yes"	""	""
"9879"	"H4 antagonist 48"	""	"Synthetic organic"	""	""	""	""	"363894173"	"71548412"	""	""	""	""	""	""	""	""	""	""	"CNC1CN(C1)c1nc2ncc(cc2n2c1nnn2)Br"	"ICGICUHMULRYIQ-UHFFFAOYSA-N"	"InChI=1S/C11H11BrN8/c1-13-7-4-19(5-7)10-11-16-17-18-20(11)8-2-6(12)3-14-9(8)15-10/h2-3,7,13H,4-5H2,1H3"	"yes"	""	""
"9352"	"harmine"	""	"Natural product"	""	""	""	""	"328083454"	"5280953"	""	""	""	""	""	""	""	"7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole"	""	""	"COc1ccc2c(c1)[nH]c1c2ccnc1C"	"BXNJHAXVSOCGBA-UHFFFAOYSA-N"	"InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3"	"yes"	""	""
"8049"	"HG-9-91-01"	""	"Synthetic organic"	""	""	""	""	"249565729"	"78357808"	""	""	""	""	""	""	""	"1-(2,4-dimethoxyphenyl)-3-(2,6-dimethylphenyl)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]urea"	""	"HY-15776"	"COc1cc(OC)ccc1N(C(=O)Nc1c(C)cccc1C)c1ncnc(c1)Nc1ccc(cc1)N1CCN(CC1)C"	"UYUHRKLITDJEHB-UHFFFAOYSA-N"	"InChI=1S/C32H37N7O3/c1-22-7-6-8-23(2)31(22)36-32(40)39(27-14-13-26(41-4)19-28(27)42-5)30-20-29(33-21-34-30)35-24-9-11-25(12-10-24)38-17-15-37(3)16-18-38/h6-14,19-21H,15-18H2,1-5H3,(H,36,40)(H,33,34,35)"	"yes"	""	""
"1204"	"histamine"	""	"Metabolite"	""	""	""	""	"135651493"	"774"	""	""	"CHEMBL90"	""	""	""	""	"2-(3H-imidazol-4-yl)ethanamine"	""	""	"NCCc1cnc[nH]1"	"NTYJJOPFIAHURM-UHFFFAOYSA-N"	"InChI=1S/C5H9N3/c6-2-1-5-3-7-4-8-5/h3-4H,1-2,6H2,(H,7,8)"	"yes"	""	""
"9685"	"HpARI"	""	"Peptide"	""	""	""	""	"348353644"	""	""	""	""	""	""	""	""	""	""	"<i>H. polygyrus</i> Alarmin Release Inhibitor"	""	""	""	"yes"	""	""
"4953"	"hsp60"	"Human"	"Peptide"	""	""	""	""	"178101651"	""	"P10809"	"ENSG00000144381"	""	""	""	""	""	""	""	"heat shock 60kD protein 1 (chaperonin)|HSP-60|mitochondrial matrix protein P1"	""	""	""	"yes"	""	""
"9582"	"HsTX1[R14A]"	""	"Peptide"	""	""	""	""	"340590213"	""	""	""	""	""	""	""	""	""	""	"KTx 6.3"	""	""	""	"yes"	""	""
"9532"	"H<sub>2</sub>S"	""	"Inorganic"	""	""	""	""	"336446918"	"402"	""	""	""	""	""	""	""	""	""	"hydrogen sulfide"	""	""	""	"yes"	""	""
"1273"	"HTMT"	""	"Synthetic organic"	""	""	""	""	"135650354"	"124846"	""	""	"CHEMBL67601"	""	""	""	""	"6-[2-(3H-imidazol-4-yl)ethylamino]-N-[4-(trifluoromethyl)phenyl]heptanamide"	""	"histamine-trifluoromethyl-toluidine|histamine-trifluoromethyltoluide|HTFMT"	"CC(NCCc1cnc[nH]1)CCCCC(=O)Nc1ccc(cc1)C(F)(F)F"	"PMKJGGBYYNEYPA-UHFFFAOYSA-N"	"InChI=1S/C19H25F3N4O/c1-14(24-11-10-17-12-23-13-25-17)4-2-3-5-18(27)26-16-8-6-15(7-9-16)19(20,21)22/h6-9,12-14,24H,2-5,10-11H2,1H3,(H,23,25)(H,26,27)"	"yes"	""	""
"7198"	"hydroxychloroquine"	""	"Synthetic organic"	"yes"	""	""	""	"178103773"	"3652"	""	""	"CHEMBL1535"	""	""	""	""	"2-({4-[(7-chloroquinolin-4-yl)amino]pentyl}(ethyl)amino)ethan-1-ol"	"hydroxychloroquine"	"Dolquine&reg;|Plaquenil&reg;"	"OCCN(CCCC(Nc1ccnc2c1ccc(c2)Cl)C)CC"	"XXSMGPRMXLTPCZ-UHFFFAOYSA-N"	"InChI=1S/C18H26ClN3O/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21)"	"yes"	"yes"	""
"7199"	"hydroxyzine"	""	"Synthetic organic"	"yes"	""	""	""	"178103774"	"3658"	""	""	"CHEMBL896"	""	""	""	""	"2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)ethan-1-ol"	"hydroxyzine"	"Atarax&reg;|hydroxyzine hydrochloride|hydroxyzine pamoate|Vistaril&reg;"	"OCCOCCN1CCN(CC1)C(c1ccc(cc1)Cl)c1ccccc1"	"ZQDWXGKKHFNSQK-UHFFFAOYSA-N"	"InChI=1S/C21H27ClN2O2/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25/h1-9,21,25H,10-17H2"	"yes"	""	""
"10656"	"ianalumab"	""	"Antibody"	""	""	""	""	"404859103"	""	""	""	""	""	""	""	""	""	"ianalumab"	"VAY-736|VAY736"	""	""	""	"yes"	""	""
"10208"	"ibalizumab"	""	"Antibody"	"yes"	""	""	""	"381744890"	""	""	""	""	""	""	""	""	""	"ibalizumab"	"Hu5A8|ibalizumab-uiyk|TMB-355|TMB355|TNX-355|Trogarzo&reg;"	""	""	""	"yes"	""	""
"9618"	"iberdomide"	""	"Synthetic organic"	""	""	""	""	"340590248"	"67335295"	""	""	""	""	""	""	""	"(3S)-3-[7-[[4-(morpholin-4-ylmethyl)phenyl]methoxy]-3-oxo-1H-isoindol-2-yl]piperidine-2,6-dione"	"iberdomide"	"CC-220|compound 6 [PMID: 28425720]"	"O=C1CC[C@@H](C(=O)N1)N1Cc2c(C1=O)cccc2OCc1ccc(cc1)CN1CCOCC1"	"IXZOHGPZAQLIBH-NRFANRHFSA-N"	"InChI=1S/C25H27N3O5/c29-23-9-8-21(24(30)26-23)28-15-20-19(25(28)31)2-1-3-22(20)33-16-18-6-4-17(5-7-18)14-27-10-12-32-13-11-27/h1-7,21H,8-16H2,(H,26,29,30)/t21-/m0/s1"	"yes"	""	""
"4218"	"iberiotoxin"	""	"Peptide"	""	""	""	""	"178101035"	"16132435"	"P24663"	""	""	""	""	""	""	"2-(2-{[10-(6-amino-2-{6-amino-2-[2-(2-{[7,34-bis(4-aminobutyl)-37-{2-[2-(2-{[10-(4-aminobutyl)-22-(3-carboxy-2-{2-[3-carboxy-2-(3-hydroxy-2-{2-[(5-oxopyrrolidin-2-yl)formamido]-3-phenylpropanamido}butanamido)propanamido]-3-methylbutanamido}propanamido)-7-(2-carboxyethyl)-13,19-bis(hydroxymethyl)-6,9,12,15,18,21-hexaoxo-16-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20-hexaazacyclotricosan-4-yl]formamido}-3-(1H-indol-3-yl)propanamido)-3-hydroxypropanamido]-3-methylbutanamido}-25-benzyl-13-(3-carbamimidamidopropyl)-16,31-bis(carboxymethyl)-28-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36-undecaoxo-19-(propan-2-yl)-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriacontan-4-yl]formamido}-4-(methylsulfanyl)butanamido)acetamido]hexanamido}hexanamido)-7-(3-carbamimidamidopropyl)-6,9-dioxo-1,2-dithia-5,8-diazacycloundecan-4-yl]formamido}-3-(4-hydroxyphenyl)propanamido)-4-carbamoylbutanoic acid"	""	"IbTX"	"NCCCCC1NC(=O)C(CSSCC(NC(=O)C(CCCCN)NC(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CC(=O)O)CC(C)C)Cc1ccccc1)C(C)C)CC(=O)O)C(=O)NC(C(=O)NCC(=O)NC(C(=O)NC(C(=O)NC1CSSCC(NC(=O)C(NC1=O)CCCNC(=N)N)C(=O)NC(C(=O)NC(C(=O)O)CCC(=O)N)Cc1ccc(cc1)O)CCCCN)CCCCN)CCSC)NC(=O)C(C(C)C)NC(=O)C(NC(=O)C(Cc1c[nH]c2c1cccc2)NC(=O)C1CSSCC(NC(=O)C(NC(=O)C(C(C)C)NC(=O)C(NC(=O)C(C(O)C)NC(=O)C(NC(=O)C2CCC(=O)N2)Cc2ccccc2)CC(=O)O)CC(=O)O)C(=O)NC(CO)C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCC(=O)O)CCCCN)CO)C(C)C)CO"	"VDNVVLOBNHIMQA-UHFFFAOYSA-N"	"InChI=1S/C179H274N50O55S7/c1-87(2)65-111-155(261)208-112(66-93-33-15-13-16-34-93)146(252)195-77-133(239)225-139(88(3)4)172(278)213-117(71-136(244)245)158(264)199-100(44-31-62-190-178(186)187)144(250)193-75-131(237)198-102(40-22-27-58-181)148(254)219-124(167(273)205-109(56-64-285-12)145(251)194-76-132(238)197-101(39-21-26-57-180)147(253)200-105(43-25-30-61-184)151(257)220-123-81-286-288-83-125(221-152(258)106(203-166(123)272)45-32-63-191-179(188)189)169(275)210-113(68-95-46-48-97(234)49-47-95)156(262)206-110(177(283)284)50-53-129(185)235)82-287-291-86-128(168(274)202-104(42-24-29-60-183)150(256)212-116(70-135(242)243)159(265)207-111)224-175(281)142(91(9)10)228-164(270)121(79-231)216-157(263)115(69-96-74-192-99-38-20-19-37-98(96)99)211-170(276)126-84-289-290-85-127(171(277)217-122(80-232)165(271)227-141(90(7)8)174(280)218-120(78-230)163(269)201-103(41-23-28-59-182)149(255)204-108(154(260)222-126)52-55-134(240)241)223-160(266)118(72-137(246)247)214-173(279)140(89(5)6)226-162(268)119(73-138(248)249)215-176(282)143(92(11)233)229-161(267)114(67-94-35-17-14-18-36-94)209-153(259)107-51-54-130(236)196-107/h13-20,33-38,46-49,74,87-92,100-128,139-143,192,230-234H,21-32,39-45,50-73,75-86,180-184H2,1-12H3,(H2,185,235)(H,193,250)(H,194,251)(H,195,252)(H,196,236)(H,197,238)(H,198,237)(H,199,264)(H,200,253)(H,201,269)(H,202,274)(H,203,272)(H,204,255)(H,205,273)(H,206,262)(H,207,265)(H,208,261)(H,209,259)(H,210,275)(H,211,276)(H,212,256)(H,213,278)(H,214,279)(H,215,282)(H,216,263)(H,217,277)(H,218,280)(H,219,254)(H,220,257)(H,221,258)(H,222,260)(H,223,266)(H,224,281)(H,225,239)(H,226,268)(H,227,271)(H,228,270)(H,229,267)(H,240,241)(H,242,243)(H,244,245)(H,246,247)(H,248,249)(H,283,284)(H4,186,187,190)(H4,188,189,191)"	"yes"	""	""
"6777"	"ibritumomab tiuxetan"	""	"Antibody"	"yes"	""	""	""	"178103383"	""	""	""	""	""	""	""	""	""	"ibritumomab tiuxetan"	"IDEC-2B8|IDEC-Y2B8-yttrium ibritumomab tiuxetan|NSC-715848|Zevalin&reg;"	""	""	""	"yes"	""	""
"6912"	"ibrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"178103494"	"24821094"	""	""	"CHEMBL1873475"	""	""	""	""	"1-[(3R)-3-[4-amino-3-(4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidin-1-yl]prop-2-en-1-one"	"ibrutinib"	"Imbruvica&reg;|PCI-32765"	"C=CC(=O)N1CCC[C@H](C1)n1nc(c2c1ncnc2N)c1ccc(cc1)Oc1ccccc1"	"XYFPWWZEPKGCCK-GOSISDBHSA-N"	"InChI=1S/C25H24N6O2/c1-2-21(32)30-14-6-7-18(15-30)31-25-22(24(26)27-16-28-25)23(29-31)17-10-12-20(13-11-17)33-19-8-4-3-5-9-19/h2-5,8-13,16,18H,1,6-7,14-15H2,(H2,26,27,28)/t18-/m1/s1"	"yes"	""	""
"7399"	"ibudilast"	""	"Synthetic organic"	"yes"	""	""	""	"178103971"	"3671"	""	""	"CHEMBL19449"	""	""	""	""	"2-methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one"	"ibudilast"	"AV-411|KC-404|Ketas&reg;|MN-166"	"CC(C(=O)c1c(nn2c1cccc2)C(C)C)C"	"ZJVFLBOZORBYFE-UHFFFAOYSA-N"	"InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3"	"yes"	""	""
"2713"	"ibuprofen"	""	"Synthetic organic"	"yes"	""	""	""	"135650365"	"3672"	""	""	"CHEMBL521"	""	""	""	""	"2-[4-(2-methylpropyl)phenyl]propanoic acid"	"ibuprofen"	"Advil&reg;|Brufen&reg;|ibuprofen lysine|ibuprofen sodium|Motrin&reg;|Nurofen&reg;|U-18573"	"CC(Cc1ccc(cc1)C(C(=O)O)C)C"	"HEFNNWSXXWATRW-UHFFFAOYSA-N"	"InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)"	"yes"	""	""
"10374"	"I-C11"	""	"Synthetic organic"	""	""	""	""	"384403654"	"25262525"	""	""	"CHEMBL260920"	""	""	""	""	"6-hydroxy-3-[1-[4-(naphthalen-1-ylamino)-4-oxobutyl]triazol-4-yl]-2-phenyl-1-benzofuran-5-carboxylic acid"	""	""	"O=C(Nc1cccc2c1cccc2)CCCn1nnc(c1)c1c(oc2c1cc(C(=O)O)c(c2)O)c1ccccc1"	"RSPKMGDZBNPGGF-UHFFFAOYSA-N"	"InChI=1S/C31H24N4O5/c36-26-17-27-23(16-22(26)31(38)39)29(30(40-27)20-9-2-1-3-10-20)25-18-35(34-33-25)15-7-14-28(37)32-24-13-6-11-19-8-4-5-12-21(19)24/h1-6,8-13,16-18,36H,7,14-15H2,(H,32,37)(H,38,39)"	"yes"	""	""
"9376"	"IC-87114"	""	"Synthetic organic"	""	""	""	""	"328083478"	"9908783"	""	""	"CHEMBL1213082"	""	""	""	""	"2-[(6-aminopurin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)quinazolin-4-one"	""	"IC87114"	"Nc1ncnc2c1ncn2Cc1nc2cccc(c2c(=O)n1c1ccccc1C)C"	"GNWHRHGTIBRNSM-UHFFFAOYSA-N"	"InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22(29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9,11-12H,10H2,1-2H3,(H2,23,24,25)"	"yes"	""	""
"12098"	"icanbelimod"	""	"Synthetic organic"	""	""	""	""	"472319220"	"117972004"	""	""	"CHEMBL4097139"	""	""	""	""	"1-[[2-fluoro-4-[5-[4-(2-methylpropyl)phenyl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid"	"icanbelimod"	"compound 2 [WO2015039587A1]|S1p-receptor-agonist-1|YUN88562"	"Fc1c(ccc(c1)c1noc(n1)c1ccc(cc1)CC(C)C)CN1CC(C1)C(=O)O"	"YBIFMTGYWXNIRZ-UHFFFAOYSA-N"	"InChI=1S/C23H24FN3O3/c1-14(2)9-15-3-5-16(6-4-15)22-25-21(26-30-22)17-7-8-18(20(24)10-17)11-27-12-19(13-27)23(28)29/h3-8,10,14,19H,9,11-13H2,1-2H3,(H,28,29)"	"yes"	""	""
"11179"	"IcatC<sub>XPZ-01</sub>"	""	"Synthetic organic"	""	""	""	""	"434122239"	"66550979"	""	""	""	""	""	""	""	"(2S)-2-amino-N-[(1R,2R)-1-cyano-2-[4-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]phenyl]cyclopropyl]butanamide"	""	"compound 8a [PMID: 30978322]|XPZ-01"	"CC[C@@H](C(=O)N[C@]1(C#N)C[C@@H]1c1ccc(cc1)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C)N"	"LJIOTBMDLVHTBO-CUYJMHBOSA-N"	"InChI=1S/C25H31N5O3S/c1-3-23(27)24(31)28-25(17-26)16-22(25)20-6-4-18(5-7-20)19-8-10-21(11-9-19)34(32,33)30-14-12-29(2)13-15-30/h4-11,22-23H,3,12-16,27H2,1-2H3,(H,28,31)/t22-,23+,25+/m1/s1"	"yes"	""	""
"667"	"icatibant"	""	"Peptide"	"yes"	""	""	""	"135652196"	"71364"	""	""	"CHEMBL2028850"	""	""	""	""	"(N-(N-(D-arginyl-DL-arginyl-DL-prolyl-(4R)-4-hydroxy-DL-prolyl-glycyl-3-(2-thienyl)-L-alanyl-L-seryl)-1,2,3,4-tetrahydroisoquinoline-3-carbonyl)-(3aS,7aS)-octahydroindole-2-carbonyl)-L-arginine"	"icatibant"	"<small>D</small>-Arg-[Hyp<sup>3</sup>,Thi<sup>5</sup>,<small>D</small>-Tic<sup>7</sup>,Oic<sup>8</sup>]BK|Firazyr&reg;|HOE 140|HOE140"	"OC[C@@H](C(=O)N1Cc2ccccc2CC1C(=O)N1[C@H]2CCCC[C@H]2CC1C(=O)N[C@H](C(=O)O)CCCN=C(N)N)NC(=O)[C@H](Cc1cccs1)NC(=O)CNC(=O)C1C[C@H](CN1C(=O)C1CCCN1C(=O)C(NC(=O)[C@@H](CCCN=C(N)N)N)CCCN=C(N)N)O"	"QURWXBZNHXJZBE-MCDGZUPGSA-N"	"InChI=1S/C59H89N19O13S/c60-37(14-5-19-67-57(61)62)48(82)72-38(15-6-20-68-58(63)64)52(86)75-22-8-18-43(75)54(88)77-30-35(80)26-44(77)50(84)70-28-47(81)71-40(27-36-13-9-23-92-36)49(83)74-41(31-79)53(87)76-29-34-12-2-1-10-32(34)24-46(76)55(89)78-42-17-4-3-11-33(42)25-45(78)51(85)73-39(56(90)91)16-7-21-69-59(65)66/h1-2,9-10,12-13,23,33,35,37-46,79-80H,3-8,11,14-22,24-31,60H2,(H,70,84)(H,71,81)(H,72,82)(H,73,85)(H,74,83)(H,90,91)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t33-,35+,37+,38?,39-,40-,41-,42-,43?,44?,45?,46?/m0/s1"	"yes"	""	""
"9593"	"ICOS ligand"	"Human"	"Peptide"	""	""	""	""	"340590224"	""	"O75144"	"ENSG00000160223"	""	""	""	""	""	""	""	"B7 homolog 2|B7-H2|B7-related protein 1|B7RP-1|CD275|ICOS-L"	""	""	""	"yes"	""	""
"14181"	"icotrokinra"	""	"Peptide"	"yes"	""	""	""	"518520808"	"162462321"	""	""	""	""	""	""	""	""	"icotrokinra"	"Icotyde&reg;|JNJ-2113|JNJ-77242113|JNJ77242113"	"CC1=C2C(=CC=C1)C(=CN2)C[C@H]3C(=O)N[C@H](C(=O)N[C@@H](C(SSC([C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N3)[C@@H](C)O)CC(=O)N)NC(=O)C)(C)C)(C)C)C(=O)N[C@@H](CC4=CC=C(C=C4)OCCN)C(=O)N[C@@H](CC5=CC6=CC=CC=C6C=C5)C(=O)NC7(CCOCC7)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC8=CN=CC=C8)C(=O)N(C)CC(=O)N)CCCCNC(=O)C"	"IVFNYXYPMJQSGF-QMRCQSNESA-N"	"InChI=1S/C90H120N20O22S2/c1-48-16-14-20-59-57(46-97-72(48)59)42-64-79(122)99-60(21-12-13-34-96-50(3)112)77(120)108-75(89(7,8)134-133-88(5,6)74(98-51(4)113)84(127)104-66(44-69(93)115)81(124)107-73(49(2)111)83(126)102-64)85(128)103-62(39-52-23-26-58(27-24-52)132-37-32-91)78(121)100-63(40-53-22-25-55-18-10-11-19-56(55)38-53)82(125)109-90(30-35-131-36-31-90)87(130)106-61(28-29-71(117)118)76(119)101-65(43-68(92)114)80(123)105-67(41-54-17-15-33-95-45-54)86(129)110(9)47-70(94)116/h10-11,14-20,22-27,33,38,45-46,49,60-67,73-75,97,111H,12-13,21,28-32,34-37,39-44,47,91H2,1-9H3,(H2,92,114)(H2,93,115)(H2,94,116)(H,96,112)(H,98,113)(H,99,122)(H,100,121)(H,101,119)(H,102,126)(H,103,128)(H,104,127)(H,105,123)(H,106,130)(H,107,124)(H,108,120)(H,109,125)(H,117,118)/t49-,60+,61+,62+,63+,64+,65+,66+,67+,73+,74-,75-/m1/s1"	"yes"	""	""
"6741"	"idelalisib"	""	"Synthetic organic"	"yes"	""	""	""	"178103352"	"11625818"	""	""	"CHEMBL2216870"	""	""	""	""	"5-fluoro-3-phenyl-2-[(1S)-1-(7H-purin-6-ylamino)propyl]quinazolin-4-one"	"idelalisib"	"CAL-101/CAL101|GS-1101|Zydelig&reg;"	"CC[C@@H](c1nc2cccc(c2c(=O)n1c1ccccc1)F)Nc1ncnc2c1[nH]cn2"	"IFSDAJWBUCMOAH-HNNXBMFYSA-N"	"InChI=1S/C22H18FN7O/c1-2-15(28-20-18-19(25-11-24-18)26-12-27-20)21-29-16-10-6-9-14(23)17(16)22(31)30(21)13-7-4-3-5-8-13/h3-12,15H,2H2,1H3,(H2,24,25,26,27,28)/t15-/m0/s1"	"yes"	""	""
"10638"	"ifidancitinib"	""	"Synthetic organic"	""	""	""	""	"404859085"	"46851625"	""	""	"CHEMBL4594441"	""	""	""	""	"5-[[2-(4-fluoro-3-methoxy-5-methylanilino)-5-methylpyrimidin-4-yl]amino]-3H-1,3-benzoxazol-2-one"	"ifidancitinib"	"A-301|ATI-50002|ATI-502"	"COc1cc(Nc2ncc(c(n2)Nc2ccc3c(c2)[nH]c(=O)o3)C)cc(c1F)C"	"OYFMQDVLFYKOPZ-UHFFFAOYSA-N"	"InChI=1S/C20H18FN5O3/c1-10-6-13(8-16(28-3)17(10)21)24-19-22-9-11(2)18(26-19)23-12-4-5-15-14(7-12)25-20(27)29-15/h4-9H,1-3H3,(H,25,27)(H2,22,23,24,26)"	"yes"	""	""
"4956"	"IFN-&alpha;10"	"Human"	"Peptide"	""	""	""	""	"178101654"	""	"P01566"	"ENSG00000186803"	""	""	""	""	""	""	""	"IFN alpha-10|interferon alpha-10|interferon alpha-6L|interferon alpha-C"	""	""	""	"yes"	""	""
"4955"	"IFN-&alpha;1/13"	"Human"	"Peptide"	""	""	""	""	"178101653"	""	"P01562"	"ENSG00000197919|ENSG00000233816"	""	""	""	""	""	""	""	"IFN-&alpha;1|IFN-&alpha;13|IFN-alpha 1/13|interferon alpha-1/13|interferon alpha-D"	""	""	""	"yes"	""	""
"4957"	"IFN-&alpha;14"	"Human"	"Peptide"	""	""	""	""	"178101655"	""	"P01570"	"ENSG00000228083"	""	""	""	""	""	""	""	"IFN alpha-14|interferon alpha-14|interferon alpha-H|interferon lambda-2-H"	""	""	""	"yes"	""	""
"4958"	"IFN-&alpha;16"	"Human"	"Peptide"	""	""	""	""	"178101656"	""	"P05015"	"ENSG00000147885"	""	""	""	""	""	""	""	"IFN alpha-16|interferon alpha-16|interferon alpha-WA"	""	""	""	"yes"	""	""
"4959"	"IFN-&alpha;17"	"Human"	"Peptide"	""	""	""	""	"178101657"	""	"P01571"	"ENSG00000234829"	""	""	""	""	""	""	""	"IFN alpha-17|interferon alpha-17|interferon alpha-88|interferon alpha-T"	""	""	""	"yes"	""	""
"4960"	"IFN-&alpha;2"	"Human"	"Peptide"	"yes"	""	""	""	"178101658"	""	"P01563"	"ENSG00000188379"	""	""	""	""	""	""	""	"IFN-alpha-2|interferon alpha-2|Roferon A&reg;"	""	""	""	"yes"	""	""
"4961"	"IFN-&alpha;21"	"Human"	"Peptide"	""	""	""	""	"178101659"	""	"P01568"	"ENSG00000137080"	""	""	""	""	""	""	""	"IFN-alpha 21|interferon alpha-21|interferon alpha-F"	""	""	""	"yes"	""	""
"4962"	"IFN-&alpha;4"	"Human"	"Peptide"	""	""	""	""	"178101660"	""	"P05014"	"ENSG00000236637"	""	""	""	""	""	""	""	"IFN-alpha-4|interferon alpha-4|interferon alpha-4B|interferon alpha-76|interferon alpha-M1"	""	""	""	"yes"	""	""
"4963"	"IFN-&alpha;5"	"Human"	"Peptide"	""	""	""	""	"178101661"	""	"P01569"	"ENSG00000147873"	""	""	""	""	""	""	""	"IFN-alpha-5|interferon alpha-5|interferon alpha-61|interferon alpha-G"	""	""	""	"yes"	""	""
"4964"	"IFN-&alpha;6"	"Human"	"Peptide"	""	""	""	""	"178101662"	""	"P05013"	"ENSG00000120235"	""	""	""	""	""	""	""	"IFN-alpha-6|interferon alpha-54|interferon alpha-6|interferon alpha-K"	""	""	""	"yes"	""	""
"4965"	"IFN-&alpha;7"	"Human"	"Peptide"	""	""	""	""	"178101663"	""	"P01567"	"ENSG00000214042"	""	""	""	""	""	""	""	"IFN-alpha-7|interferon alpha-7|interferon alpha-J|interferon alpha-J1"	""	""	""	"yes"	""	""
"4966"	"IFN-&alpha;8"	"Human"	"Peptide"	""	""	""	""	"178101664"	""	"P32881"	"ENSG00000120242"	""	""	""	""	""	""	""	"IFN-alpha-8|interferon alpha-8|interferon alpha-B|interferon alpha-B2"	""	""	""	"yes"	""	""
"4967"	"IFN-&beta;"	"Human"	"Peptide"	""	""	""	""	"178101665"	""	"P01574"	"ENSG00000171855"	""	""	""	""	""	""	"interferon beta"	"Avonex&reg; (recombinant IFN-beta-1a)|fibroblast interferon|interferon beta"	""	""	""	"yes"	""	""
"8340"	"IFN-&beta;1b (recombinant human)"	""	"Peptide"	"yes"	""	""	""	"252166552"	""	""	""	""	""	""	""	""	""	"interferon beta"	"Betaferon&reg;|Betaseron&reg;|Extavia&reg;|IFNb1b"	""	""	""	"yes"	""	""
"4968"	"IFN-&gamma;"	"Human"	"Peptide"	"yes"	""	""	""	"178101666"	""	"P01579"	"ENSG00000111537"	""	""	""	""	""	""	""	"Actimmune&reg;|immune interferon|interferon gamma"	""	""	""	"yes"	""	""
"4969"	"IFN-&kappa;"	"Human"	"Peptide"	""	""	""	""	"178101667"	""	"Q9P0W0"	"ENSG00000147896"	""	""	""	""	""	""	""	"interferon kappa"	""	""	""	"yes"	""	""
"4993"	"IFN-&lambda;1"	"Human"	"Peptide"	""	""	""	""	"178101690"	""	"Q8IU54"	"ENSG00000182393"	""	""	""	""	""	""	""	"IFN-lambda-1|interferon lambda-1|interferon-&lambda;1|interleukin-29"	""	""	""	"yes"	""	""
"4991"	"IFN-&lambda;2"	"Human"	"Peptide"	""	""	""	""	"178101688"	""	"Q8IZJ0"	"ENSG00000183709"	""	""	""	""	""	""	""	"cytokine Zcyto20|IFN-lambda-2|interferon lambda-2|interferon-&lambda;2|interleukin-28A"	""	""	""	"yes"	""	""
"4992"	"IFN-&lambda;3"	"Human"	"Peptide"	""	""	""	""	"178101689"	""	"Q8IZI9"	"ENSG00000197110"	""	""	""	""	""	""	""	"cytokine Zcyto22|IFN-lambda-3|IFN-lambda-4|interleukin-28B (IL-28B)|interleukin-28C (IL-28C)"	""	""	""	"yes"	""	""
"4970"	"IFN-&omega;"	"Human"	"Peptide"	""	""	""	""	"178101668"	""	"P05000"	"ENSG00000177047"	""	""	""	""	""	""	""	"interferon alpha-II-1|interferon omega-1"	""	""	""	"yes"	""	""
"9557"	"IgE heavy chain"	""	"Peptide"	""	""	""	""	"336446943"	""	"P01854"	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9736"	"iguratimod"	""	"Synthetic organic"	"yes"	""	""	""	"354702212"	"124246"	""	""	"CHEMBL2107455"	""	""	""	""	"N-[7-methanesulfonamido-4-oxo-6-(phenoxy)chromen-3-yl]formamide"	"iguratimod"	"Careram&reg;|Iremod|Kolbet&reg;|T-614"	"O=CNc1coc2c(c1=O)cc(c(c2)NS(=O)(=O)C)Oc1ccccc1"	"ANMATWQYLIFGOK-UHFFFAOYSA-N"	"InChI=1S/C17H14N2O6S/c1-26(22,23)19-13-8-15-12(17(21)14(9-24-15)18-10-20)7-16(13)25-11-5-3-2-4-6-11/h2-10,19H,1H3,(H,18,20)"	"yes"	""	""
"9713"	"<i>H. polygyrus</i> TGF-&beta; mimic"	""	"Peptide"	""	""	""	""	"348353672"	""	""	""	""	""	""	""	""	""	""	"<i>Hp</i>-TGM"	""	""	""	"yes"	""	""
"5986"	"IKK-2 inhibitor IV"	""	"Synthetic organic"	""	""	""	""	"178102609"	"9903786"	""	""	"CHEMBL257167"	""	""	""	""	"2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide"	""	"TPCA-1|TPCA1"	"NC(=O)Nc1sc(cc1C(=O)N)c1ccc(cc1)F"	"SAYGKHKXGCPTLX-UHFFFAOYSA-N"	"InChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)"	"yes"	""	""
"10134"	"IKK-beta inhibitor R-28"	""	"Synthetic organic"	""	""	""	""	"381118844"	"59332591"	""	""	""	""	""	""	""	"3-[(4R)-2,2-dimethyl-1,1-dioxothian-4-yl]-5-(4-fluorophenyl)-1H-indole-7-carboxamide"	""	"(R)-28|example 225 [US8372875B2]"	"Fc1ccc(cc1)c1cc(C(=O)N)c2c(c1)c(c[nH]2)[C@@H]1CCS(=O)(=O)C(C1)(C)C"	"YGYGASJNJTYNOL-CQSZACIVSA-N"	"InChI=1S/C22H23FN2O3S/c1-22(2)11-14(7-8-29(22,27)28)19-12-25-20-17(19)9-15(10-18(20)21(24)26)13-3-5-16(23)6-4-13/h3-6,9-10,12,14,25H,7-8,11H2,1-2H3,(H2,24,26)/t14-/m1/s1"	"yes"	""	""
"4975"	"IL-10"	"Human"	"Peptide"	""	""	""	""	"178101673"	""	"P22301"	"ENSG00000136634"	""	""	""	""	""	""	""	"interleukin-10"	""	""	""	"yes"	""	""
"4976"	"IL-11"	"Human"	"Peptide"	""	""	""	""	"178101674"	""	"P20809"	"ENSG00000095752"	""	""	""	""	""	""	""	"interleukin-11"	""	""	""	"yes"	""	""
"4977"	"IL-12"	"Human"	"Peptide"	""	""	""	""	"178101675"	""	""	"ENSG00000168811|ENSG00000113302"	""	""	""	""	""	""	""	"IL-12 p70"	""	""	""	"yes"	""	""
"5001"	"IL-12A"	"Human"	"Peptide"	""	""	""	""	"178101698"	""	"P29459"	"ENSG00000168811"	""	""	""	""	""	""	""	"IL-12 p35|interleukin-12A|NKSF1"	""	""	""	"yes"	""	""
"5002"	"IL-12B"	"Human"	"Peptide"	""	""	""	""	"178101699"	""	"P29460"	"ENSG00000113302"	""	""	""	""	""	""	""	"IL-12 p40|IL-12B monomer|interleukin-12&beta;|interleukin-12B|natural killer cell stimulatory factor 2"	""	""	""	"yes"	""	""
"4980"	"IL-13"	"Human"	"Peptide"	""	""	""	""	"178101677"	""	"P35225"	"ENSG00000169194"	""	""	""	""	""	""	""	"hematopoietic growth factor|interleukin-13|mast cell growth factor|multipotential colony-stimulating factor|P-cell-stimulating factor"	""	""	""	"yes"	""	""
"4981"	"IL-15"	"Human"	"Peptide"	""	""	""	""	"178101678"	""	"P40933"	"ENSG00000164136"	""	""	""	""	""	""	""	"interleukin-15"	""	""	""	"yes"	""	""
"4982"	"IL-17A"	"Human"	"Peptide"	""	""	""	""	"178101679"	""	"Q16552"	"ENSG00000112115"	""	""	""	""	""	""	""	"CTLA-8|interleukin-17 alpha"	""	""	""	"yes"	""	""
"5874"	"IL-17A/IL-17F"	"Human"	"Peptide"	""	""	""	""	"178102498"	""	""	"ENSG00000112115|ENSG00000112116"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"5877"	"IL-17B"	"Human"	"Peptide"	""	""	""	""	"178102501"	""	"Q9UHF5"	"ENSG00000127743"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"5875"	"IL-17C"	"Human"	"Peptide"	""	""	""	""	"178102499"	""	"Q9P0M4"	"ENSG00000124391"	""	""	""	""	""	""	""	"cytokine CX2|interleukin-17C"	""	""	""	"yes"	""	""
"5873"	"IL-17F"	"Human"	"Peptide"	""	""	""	""	"178102497"	""	"Q96PD4"	"ENSG00000112116"	""	""	""	""	""	""	""	"cytokine ML-1|Interleukin-17F"	""	""	""	"yes"	""	""
"4983"	"IL-18"	"Human"	"Peptide"	""	""	""	""	"178101680"	""	"Q14116"	"ENSG00000150782"	""	""	""	""	""	""	""	"ibocatdekin|interferon-&gamma;-inducing factor|interleukin-1 gamma (IL-1 gamma)|interleukin-18"	""	""	""	"yes"	""	""
"4984"	"IL-19"	"Human"	"Peptide"	""	""	""	""	"178101681"	""	"Q9UHD0"	"ENSG00000142224"	""	""	""	""	""	""	""	"interleukin-19|melanoma differentiation-associated protein-like protein"	""	""	""	"yes"	""	""
"4973"	"IL-1&alpha;"	"Human"	"Peptide"	""	""	""	""	"178101671"	""	"P01583"	"ENSG00000115008"	""	""	""	""	""	""	""	"hematopoietin-1|interleukin-1 alpha"	""	""	""	"yes"	""	""
"4974"	"IL-1&beta;"	"Human"	"Peptide"	""	""	""	""	"178101672"	""	"P01584"	"ENSG00000125538"	""	""	""	""	""	""	""	"catabolin|interleukin-1 beta"	""	""	""	"yes"	""	""
"5878"	"IL-1 receptor antagonist"	"Human"	"Peptide"	""	""	""	""	"178102502"	""	"P18510"	"ENSG00000136689"	""	""	""	""	""	""	""	"IL-1ra|interleukin-1 receptor antagonist protein|IRAP"	""	""	""	"yes"	""	""
"4985"	"IL-2"	"Human"	"Peptide"	"yes"	""	""	""	"178101682"	""	"P60568"	"ENSG00000109471"	""	""	""	""	""	""	""	"aldesleukin|interleukin-2|Proleukin&reg;"	""	""	""	"yes"	""	""
"4986"	"IL-20"	"Human"	"Peptide"	""	""	""	""	"178101683"	""	"Q9NYY1"	"ENSG00000162891"	""	""	""	""	""	""	""	"cytokine Zcyto10|interleukin-20"	""	""	""	"yes"	""	""
"4987"	"IL-21"	"Human"	"Peptide"	""	""	""	""	"178101684"	""	"Q9HBE4"	"ENSG00000138684"	""	""	""	""	""	""	""	"interleukin-21|ZA11"	""	""	""	"yes"	""	""
"4988"	"IL-22"	"Human"	"Peptide"	""	""	""	""	"178101685"	""	"Q9GZX6"	"ENSG00000127318"	""	""	""	""	""	""	""	"cytokine Zcyto18|interleukin-22"	""	""	""	"yes"	""	""
"4978"	"IL-23"	"Human"	"Peptide"	""	""	""	""	"178101676"	""	""	"ENSG00000113302|ENSG00000110944"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4989"	"IL-23A"	"Human"	"Peptide"	""	""	""	""	"178101686"	""	""	"ENSG00000110944"	""	""	""	""	""	""	""	"IL-23p19|IL23A|interleukin-23 subunit alpha|interleukin-23A"	""	""	""	"yes"	""	""
"4990"	"IL-24"	"Human"	"Peptide"	""	""	""	""	"178101687"	""	"Q13007"	"ENSG00000162892"	""	""	""	""	""	""	""	"interleukin-24|MDA-7|melanoma differentiation-associated gene 7 protein"	""	""	""	"yes"	""	""
"5876"	"IL-25"	"Human"	"Peptide"	""	""	""	""	"178102500"	""	"Q9H293"	"ENSG00000166090"	""	""	""	""	""	""	""	"IL-17E|interleukin-17E|interleukin-25"	""	""	""	"yes"	""	""
"6151"	"IL-27"	"Human"	"Peptide"	""	""	""	""	"178102772"	""	""	"ENSG00000105246|ENSG00000197272"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"6152"	"IL-27 subunit &alpha;"	"Human"	"Peptide"	""	""	""	""	"178102773"	""	"Q8NEV9"	"ENSG00000197272"	""	""	""	""	""	""	""	"IL-27 subunit alpha|interleukin-27 subunit alpha|p28"	""	""	""	"yes"	""	""
"6153"	"IL-27 subunit &beta;"	"Human"	"Peptide"	""	""	""	""	"178102774"	""	"Q14213"	"ENSG00000105246"	""	""	""	""	""	""	""	"EBV-induced gene 3 protein|Epstein-Barr virus-induced gene 3 protein|IL-27 subunit beta|IL-27B|interleukin-27 subunit beta"	""	""	""	"yes"	""	""
"4994"	"IL-3"	"Human"	"Peptide"	""	""	""	""	"178101691"	""	"P08700"	"ENSG00000164399"	""	""	""	""	""	""	""	"interleukin-3 (IL-3)|multilineage-colony-stimulating factor (mCSF)"	""	""	""	"yes"	""	""
"4995"	"IL-31"	"Human"	"Peptide"	""	""	""	""	"178101692"	""	"Q6EBC2"	"ENSG00000204671"	""	""	""	""	""	""	""	"interleukin-31"	""	""	""	"yes"	""	""
"5880"	"IL-33"	"Human"	"Peptide"	""	""	""	""	"178102504"	""	"O95760"	"ENSG00000137033"	""	""	""	""	""	""	""	"IL-1F11"	""	""	""	"yes"	""	""
"8975"	"IL-34"	"Human"	"Peptide"	""	""	""	""	"310264755"	""	"Q6ZMJ4"	"ENSG00000157368"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"5881"	"IL-36&alpha;"	"Human"	"Peptide"	""	""	""	""	"178102505"	""	"Q9UHA7"	"ENSG00000136694"	""	""	""	""	""	""	""	"FIL1 epsilon|interleukin-1 epsilon (IL-1 epsilon)"	""	""	""	"yes"	""	""
"5882"	"IL-36&beta;"	"Human"	"Peptide"	""	""	""	""	"178102506"	""	"Q9NZH7"	"ENSG00000136696"	""	""	""	""	""	""	""	"FIL1 eta|IL-1 eta|interleukin-1 eta"	""	""	""	"yes"	""	""
"5883"	"IL-36&gamma;"	"Human"	"Peptide"	""	""	""	""	"178102507"	""	"Q9NZH8"	"ENSG00000136688"	""	""	""	""	""	""	""	"IL-1-related protein 2 (IL-1RP2)|interleukin-1 epsilon (IL-1E)|interleukin-1 family member 9|interleukin-36 gamma"	""	""	""	"yes"	""	""
"5879"	"IL-36 receptor antagonist"	"Human"	"Peptide"	""	""	""	""	"178102503"	""	"Q9UBH0"	"ENSG00000136695"	""	""	""	""	""	""	""	"IL-1 related protein 3 (IL1RP3)|IL-1F5|IL-36ra|IL1F5|interleukin 1 family member 5 (delta)"	""	""	""	"yes"	""	""
"6149"	"IL-37"	"Human"	"Peptide"	""	""	""	""	"178102770"	""	"Q9NZH6"	"ENSG00000125571"	""	""	""	""	""	""	""	"IL-1&zeta;|IL-23|interleukin-1&zeta;|interleukin-1-related protein (IL1RP)|interleukin-23"	""	""	""	"yes"	""	""
"4996"	"IL-4"	"Human"	"Peptide"	""	""	""	""	"178101693"	""	"P05112"	"ENSG00000113520"	""	""	""	""	""	""	""	"B-cell stimulatory factor 1|binetrakin|interleukin-4|pitrakinra"	""	""	""	"yes"	""	""
"4997"	"IL-5"	"Human"	"Peptide"	""	""	""	""	"178101694"	""	"P05113"	"ENSG00000113525"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4998"	"IL-6"	"Human"	"Peptide"	""	""	""	""	"178101695"	""	"P05231"	"ENSG00000136244"	""	""	""	""	""	""	""	"B-cell stimulatory factor 2|CTL differentiation factor|hybridoma growth factor|interferon &beta;2|interleukin-6"	""	""	""	"yes"	""	""
"4999"	"IL-7"	"Human"	"Peptide"	""	""	""	""	"178101696"	""	"P13232"	"ENSG00000104432"	""	""	""	""	""	""	""	"interleukin-7"	""	""	""	"yes"	""	""
"5000"	"IL-9"	"Human"	"Peptide"	""	""	""	""	"178101697"	""	"P15248"	"ENSG00000145839"	""	""	""	""	""	""	""	"interleukin-9"	""	""	""	"yes"	""	""
"1895"	"iloprost"	""	"Synthetic organic"	"yes"	""	""	""	"135650378"	"6435378"	""	""	"CHEMBL236025"	""	""	""	""	"(5E)-5-[(3aS,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxy-4-methyloct-1-en-6-ynyl]-3,3a,4,5,6,6a-hexahydro-1H-pentalen-2-ylidene]pentanoic acid"	"iloprost"	"Aurlumyn&reg;|Ventavis&reg;"	"CC#CCC([C@@H](/C=C/C1[C@H](O)C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/C2)O)C"	"HIFJCPQKFCZDDL-SGSAMSKHSA-N"	"InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15?,17-,18?,19-,20+,21+/m0/s1"	"yes"	""	""
"9805"	"imaprelimab"	""	"Antibody"	""	""	""	""	"354702277"	""	""	""	""	""	""	""	""	""	"imaprelimab"	"PRX-003|PRX003"	""	""	""	"yes"	""	""
"11153"	"imaradenant"	""	"Synthetic organic"	""	""	""	""	"434122213"	"86676119"	""	""	""	""	""	""	""	""	"imaradenant"	"AZD-4635|AZD4635"	"Nc1nnc(c(n1)c1ccc(cc1)F)c1cc(C)nc(c1)Cl"	"NCWQLHHDGDXIJN-UHFFFAOYSA-N"	"InChI=1S/C15H11ClFN5/c1-8-6-10(7-12(16)19-8)14-13(20-15(18)22-21-14)9-2-4-11(17)5-3-9/h2-7H,1H3,(H2,18,20,22)"	"yes"	""	""
"5687"	"imatinib"	""	"Synthetic organic"	"yes"	""	""	""	"178102314"	"5291"	""	""	"CHEMBL941"	""	""	""	""	"N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide"	"imatinib"	"CGP 57148|Gleevec&reg;|Glivec&reg;|STI571"	"CN1CCN(CC1)Cc1ccc(cc1)C(=O)Nc1ccc(c(c1)Nc1nccc(n1)c1cccnc1)C"	"KTUFNOKKBVMGRW-UHFFFAOYSA-N"	"InChI=1S/C29H31N7O/c1-21-5-10-25(18-27(21)34-29-31-13-11-26(33-29)24-4-3-12-30-19-24)32-28(37)23-8-6-22(7-9-23)20-36-16-14-35(2)15-17-36/h3-13,18-19H,14-17,20H2,1-2H3,(H,32,37)(H,31,33,34)"	"yes"	""	"yes"
"1250"	"imetit"	""	"Synthetic organic"	""	""	""	""	"135650381"	"3692"	""	""	"CHEMBL19439"	""	""	""	""	"2-(3H-imidazol-4-yl)ethylsulfanylmethanimidamide"	""	""	"NC(=N)SCCc1cnc[nH]1"	"PEHSVUKQDJULKE-UHFFFAOYSA-N"	"InChI=1S/C6H10N4S/c7-6(8)11-2-1-5-3-9-4-10-5/h3-4H,1-2H2,(H3,7,8)(H,9,10)"	"yes"	""	""
"5003"	"imiquimod"	""	"Synthetic organic"	"yes"	""	""	""	"178101700"	"57469"	""	""	"CHEMBL1282"	""	""	""	""	"1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine"	"imiquimod"	"Aldara&reg;|R837|S-26308|Zyclara&reg;"	"CC(Cn1cnc2c1c1ccccc1nc2N)C"	"DOUYETYNHWVLEO-UHFFFAOYSA-N"	"InChI=1S/C14H16N4/c1-9(2)7-18-8-16-12-13(18)10-5-3-4-6-11(10)17-14(12)15/h3-6,8-9H,7H2,1-2H3,(H2,15,17)"	"yes"	""	""
"1251"	"immepip"	""	"Synthetic organic"	""	""	""	""	"135650385"	"3035842"	""	""	"CHEMBL18661"	""	""	""	""	"4-(3H-imidazol-4-ylmethyl)piperidine"	""	""	"N1CCC(CC1)Cc1[nH]cnc1"	"MCNGUYXRBCIGOV-UHFFFAOYSA-N"	"InChI=1S/C9H15N3/c1-3-10-4-2-8(1)5-9-6-11-7-12-9/h6-8,10H,1-5H2,(H,11,12)"	"yes"	""	""
"1226"	"impromidine"	""	"Synthetic organic"	""	""	""	""	"135650388"	"41376"	""	""	"CHEMBL12608"	""	""	""	""	"2-[3-(3H-imidazol-4-yl)propyl]-1-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine"	"impromidine"	"SK&F-92676-A3"	"NC(=NCCCc1cnc[nH]1)NCCSCc1nc[nH]c1C"	"MURRAGMMNAYLNA-UHFFFAOYSA-N"	"InChI=1S/C14H23N7S/c1-11-13(21-10-19-11)8-22-6-5-18-14(15)17-4-2-3-12-7-16-9-20-12/h7,9-10H,2-6,8H2,1H3,(H,16,20)(H,19,21)(H3,15,17,18)"	"yes"	""	""
"14553"	"imsidolimab"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"imsidolimab"	"ANB-019|ANB019"	""	""	""	"yes"	""	""
"9045"	"INCB3284"	""	"Synthetic organic"	""	""	""	""	"315661130"	"11527661"	""	""	""	""	""	""	""	"N-[2-[[(3R)-1-[4-hydroxy-4-(6-methoxypyridin-3-yl)cyclohexyl]pyrrolidin-3-yl]amino]-2-oxoethyl]-3-(trifluoromethyl)benzamide"	""	"compound 13 [PMID: 24900329]|INCB 3284"	"COc1ccc(cn1)C1(O)CCC(CC1)N1CC[C@H](C1)NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F"	"NXZNYBUBXWWKCP-JMOWIOHXSA-N"	"InChI=1S/C26H31F3N4O4/c1-37-23-6-5-19(14-30-23)25(36)10-7-21(8-11-25)33-12-9-20(16-33)32-22(34)15-31-24(35)17-3-2-4-18(13-17)26(27,28)29/h2-6,13-14,20-21,36H,7-12,15-16H2,1H3,(H,31,35)(H,32,34)/t20-,21?,25?/m1/s1"	"yes"	""	""
"9032"	"INCB8761"	""	"Synthetic organic"	""	""	""	""	"315661117"	"11192346"	""	""	"CHEMBL2029422"	""	""	""	""	"N-[2-[(3S)-3-[[4-hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide"	""	"compound 17 [PMID: 24900280]|INCB-8761|PF-4136309|PF4136309"	"O=C(N1CC[C@@H](C1)NC1CCC(CC1)(O)c1ccc(cn1)c1ncccn1)CNC(=O)c1cccc(c1)C(F)(F)F"	"ZNSVOHSYDRPBGI-CBQRAPNFSA-N"	"InChI=1S/C29H31F3N6O3/c30-29(31,32)21-4-1-3-19(15-21)27(40)36-17-25(39)38-14-9-23(18-38)37-22-7-10-28(41,11-8-22)24-6-5-20(16-35-24)26-33-12-2-13-34-26/h1-6,12-13,15-16,22-23,37,41H,7-11,14,17-18H2,(H,36,40)/t22?,23-,28?/m0/s1"	"yes"	""	""
"12312"	"inclacumab"	""	"Antibody"	""	""	""	""	"479821103"	""	""	""	""	""	""	""	""	""	"inclacumab"	"HuMab 002|LC1004-002|RO-4905417|RO4905417"	""	""	""	"yes"	""	""
"7455"	"indacaterol"	""	"Synthetic organic"	"yes"	""	""	""	"187051758"	"6918554"	""	""	"CHEMBL1095777"	""	""	""	""	"5-[(1R)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxy-1H-quinolin-2-one"	"indacaterol"	"Arcapta Neohaler&reg;|Onbrez&reg;|QAB-149|QAB149"	"CCc1cc2CC(Cc2cc1CC)NC[C@@H](c1ccc(c2c1ccc(=O)[nH]2)O)O"	"QZZUEBNBZAPZLX-QFIPXVFZSA-N"	"InChI=1S/C24H28N2O3/c1-3-14-9-16-11-18(12-17(16)10-15(14)4-2)25-13-22(28)19-5-7-21(27)24-20(19)6-8-23(29)26-24/h5-10,18,22,25,27-28H,3-4,11-13H2,1-2H3,(H,26,29)/t22-/m0/s1"	"yes"	""	""
"10047"	"indole-3-carbinol"	""	"Synthetic organic"	""	""	""	""	"375973235"	"3712"	""	""	"CHEMBL155625"	""	""	""	""	"1H-indol-3-ylmethanol"	""	"3-hydroxymethylindole|3-indolemethanol|3-indolylcarbinol|I3C"	"OCc1c[nH]c2c1cccc2"	"IVYPNXXAYMYVSP-UHFFFAOYSA-N"	"InChI=1S/C9H9NO/c11-6-7-5-10-9-4-2-1-3-8(7)9/h1-5,10-11H,6H2"	"yes"	""	""
"1909"	"indomethacin"	""	"Synthetic organic"	"yes"	""	""	""	"135650390"	"3715"	""	""	"CHEMBL6"	""	""	""	""	"2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid"	"indometacin"	"Indocid&reg;|Indocin&reg;"	"COc1ccc2c(c1)c(CC(=O)O)c(n2C(=O)c1ccc(cc1)Cl)C"	"CGIGDMFJXJATDK-UHFFFAOYSA-N"	"InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23)"	"yes"	""	""
"5004"	"infliximab"	""	"Antibody"	"yes"	""	""	""	"178101701"	""	""	""	""	""	""	""	""	""	"infliximab"	"cA2|Inflectra&reg;|Remicade&reg;|Remsima&reg;|SB2|TA-650|Zymfentra&reg; (subcutaneous formulation)"	""	""	""	"yes"	""	""
"9898"	"inhibitor 32 [PMID: 29620892]"	""	"Synthetic organic"	""	""	""	""	"363894192"	"133081969"	""	""	""	""	""	""	""	""	""	""	"CCCC[C@H](NC(=O)CCCCC(=O)Nc1ccccc1)CCCC(=O)NO"	"ZYFVLHYHXNFROE-KRWDZBQOSA-N"	"InChI=1S/C21H33N3O4/c1-2-3-10-17(13-9-16-21(27)24-28)22-19(25)14-7-8-15-20(26)23-18-11-5-4-6-12-18/h4-6,11-12,17,28H,2-3,7-10,13-16H2,1H3,(H,22,25)(H,23,26)(H,24,27)/t17-/m0/s1"	"yes"	""	""
"13113"	"inhibitor M9 [PMID: 38236416]"	""	"Synthetic organic"	""	""	""	""	"491299895"	"171037437"	""	""	""	""	""	""	""	"4-(3-((1R,3R,5S,7R)-3,5-Dimethyladamantan-1-yl)ureido)-N-(7-(hydroxyamino)-7-oxoheptyl)benzamide"	""	""	"O=C(NC1=CC=C(C(NCCCCCCC(NO)=O)=O)C=C1)N[C@]23C[C@H]4C[C@@](C[C@](C2)(C)C4)(C)C3"	"LICDGBVIDDVNJZ-IIEILYMYSA-N"	"InChI=1S/C27H40N4O4/c1-25-13-19-14-26(2,16-25)18-27(15-19,17-25)30-24(34)29-21-10-8-20(9-11-21)23(33)28-12-6-4-3-5-7-22(32)31-35/h8-11,19,35H,3-7,12-18H2,1-2H3,(H,28,33)(H,31,32)(H2,29,30,34)/t19-,25+,26-,27-"	"yes"	""	""
"8266"	"inotuzumab ozogamicin"	""	"Antibody"	"yes"	""	""	""	"252166478"	""	""	""	""	""	""	""	""	""	"inotuzumab ozogamicin"	"Besponsa&reg;|CMC-544"	""	""	""	"yes"	""	""
"14474"	"interleukin-17D"	"Human"	"Peptide"	""	""	""	""	""	""	"Q8TAD2"	"ENSG00000172458"	""	""	""	""	""	""	""	"IL-17D"	""	""	""	"yes"	""	""
"13868"	"interleukin 18 binding protein"	"Human"	"Peptide"	""	""	""	""	"513757553"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"6888"	"ipilimumab"	""	"Antibody"	"yes"	""	""	""	"178103470"	""	""	""	""	""	""	""	""	""	"ipilimumab"	"MDX-010|MDX-101|MDX-CTLA-4|Yervoy&reg;"	""	""	""	"yes"	""	""
"325"	"ipratropium"	""	"Synthetic organic"	"yes"	""	""	""	"135650410"	"3746"	""	""	"ChEMBL1615433"	""	""	""	""	"(8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate"	"ipratropium bromide"	"Atrovent&reg;|Ipraxa&reg;"	"OCC(c1ccccc1)C(=O)OC1CC2CCC(C1)[N+]2(C)C(C)C"	"OEXHQOGQTVQTAT-UHFFFAOYSA-N"	"InChI=1S/C20H30NO3/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15/h4-8,14,16-19,22H,9-13H2,1-3H3/q+1"	"yes"	""	""
"10710"	"iptacopan"	""	"Synthetic organic"	"yes"	""	""	""	"404859157"	"90467622"	""	""	""	""	""	""	""	"4-[(2S,4S)-4-ethoxy-1-[(5-methoxy-7-methyl-1H-indol-4-yl)methyl]piperidin-2-yl]benzoic acid"	"iptacopan"	"compound 41 [PMID: 32073845]|Fabhalta&reg;|LNP-023|LNP023"	"CCO[C@H]1CCN([C@@H](C1)c1ccc(cc1)C(=O)O)Cc1c(OC)cc(c2c1cc[nH]2)C"	"RENRQMCACQEWFC-UGKGYDQZSA-N"	"InChI=1S/C25H30N2O4/c1-4-31-19-10-12-27(22(14-19)17-5-7-18(8-6-17)25(28)29)15-21-20-9-11-26-24(20)16(2)13-23(21)30-3/h5-9,11,13,19,22,26H,4,10,12,14-15H2,1-3H3,(H,28,29)/t19-,22-/m0/s1"	"yes"	""	""
"5990"	"IRAK-1/4 inhibitor"	""	"Synthetic organic"	""	""	""	""	"178102612"	"11983295"	""	""	"CHEMBL379787"	""	""	""	""	"N-{1-[2-(morpholin-4-yl)ethyl]-1H-1,3-benzodiazol-2-yl}-3-nitrobenzamide"	""	""	"O=C(c1cccc(c1)[N+](=O)[O-])Nc1nc2c(n1CCN1CCOCC1)cccc2"	"QTCFYQHZJIIHBS-UHFFFAOYSA-N"	"InChI=1S/C20H21N5O4/c26-19(15-4-3-5-16(14-15)25(27)28)22-20-21-17-6-1-2-7-18(17)24(20)9-8-23-10-12-29-13-11-23/h1-7,14H,8-13H2,(H,21,22,26)"	"yes"	""	""
"8080"	"IRAK4 inhibitor 4b [PMID: 18474425]"	""	"Synthetic organic"	""	""	""	""	"249565760"	"44449334"	""	""	"CHEMBL256713"	""	""	""	""	"N-[2-methoxy-4-(morpholin-4-yl)phenyl]-6-(1H-pyrazol-5-yl)pyridine-2-carboxamide"	""	""	"COc1cc(ccc1NC(=O)c1cccc(n1)c1ccn[nH]1)N1CCOCC1"	"RAFFLDOJXQAJPF-UHFFFAOYSA-N"	"InChI=1S/C20H21N5O3/c1-27-19-13-14(25-9-11-28-12-10-25)5-6-17(19)23-20(26)18-4-2-3-15(22-18)16-7-8-21-24-16/h2-8,13H,9-12H2,1H3,(H,21,24)(H,23,26)"	"yes"	""	""
"8081"	"IRAK4 inhibitor rac-45 [PMID: 18501603]"	""	"Synthetic organic"	""	""	""	""	"249565761"	"25169383"	""	""	"CHEMBL401633"	""	""	""	""	"6-{6-chloroimidazo[1,2-a]pyridin-3-yl}-N-(pyrrolidin-3-yl)pyridin-2-amine"	""	""	"Clc1ccc2n(c1)c(cn2)c1cccc(n1)NC1CNCC1"	"NAMQQRIYZTTYCJ-UHFFFAOYSA-N"	"InChI=1S/C16H16ClN5/c17-11-4-5-16-19-9-14(22(16)10-11)13-2-1-3-15(21-13)20-12-6-7-18-8-12/h1-5,9-10,12,18H,6-8H2,(H,20,21)"	"yes"	""	""
"1236"	"(<i>R</i>)-&alpha;-methylhistamine"	""	"Synthetic organic"	""	""	""	""	"135650415"	"156615"	""	""	"CHEMBL268229"	""	""	""	""	"(2R)-1-(3H-imidazol-4-yl)propan-2-amine"	""	"(<i>R</i>)-&alpha;-MeHA|alpha-methylhistamine"	"C[C@H](Cc1cnc[nH]1)N"	"XNQIOISZPFVUFG-RXMQYKEDSA-N"	"InChI=1S/C6H11N3/c1-5(7)2-6-3-8-4-9-6/h3-5H,2,7H2,1H3,(H,8,9)/t5-/m1/s1"	"yes"	""	""
"9000"	"(<i>R</i>)-ARN2508"	""	"Synthetic organic"	""	""	""	""	"310264778"	"117072557"	""	""	""	""	""	""	""	"(2R)-2-(3-fluoro-4-{3-[(hexylcarbamoyl)oxy]phenyl}phenyl)propanoic acid"	""	"compound (-)-10r [PMID: 26774927]|example 19 [WO2014023643]"	"CCCCCCNC(=O)Oc1cccc(c1)c1ccc(cc1F)[C@H](C(=O)O)C"	"USQOVYLRWBOSQC-OAHLLOKOSA-N"	"InChI=1S/C22H26FNO4/c1-3-4-5-6-12-24-22(27)28-18-9-7-8-17(13-18)19-11-10-16(14-20(19)23)15(2)21(25)26/h7-11,13-15H,3-6,12H2,1-2H3,(H,24,27)(H,25,26)/t15-/m1/s1"	"yes"	""	""
"9802"	"iscalimab"	""	"Antibody"	""	""	""	""	"354702274"	""	""	""	""	""	""	""	""	""	"iscalimab"	"CFZ-533|CFZ533|NVP-CFZ533|OM11-62MF"	""	""	""	"yes"	""	""
"9796"	"(<i>S</i>)-23 [PMID: 27933945]"	""	"Synthetic organic"	""	""	""	""	"354702268"	"122707120"	""	""	""	""	""	""	""	"2-fluoro-5-[2-[(4S)-4-(4-methyl-1,1-dioxothian-4-yl)-2-oxopyrrolidin-1-yl]ethoxy]benzonitrile"	""	""	"N#Cc1cc(OCCN2C[C@@H](CC2=O)C2(C)CCS(=O)(=O)CC2)ccc1F"	"SYEMWCXBADSSGE-OAHLLOKOSA-N"	"InChI=1S/C19H23FN2O4S/c1-19(4-8-27(24,25)9-5-19)15-11-18(23)22(13-15)6-7-26-16-2-3-17(20)14(10-16)12-21/h2-3,10,15H,4-9,11,13H2,1H3/t15-/m1/s1"	"yes"	""	""
"8999"	"(<i>S</i>)-ARN2508"	""	"Synthetic organic"	""	""	""	""	"310264777"	"117072556"	""	""	""	""	""	""	""	"(2S)-2-(3-fluoro-4-{3-[(hexylcarbamoyl)oxy]phenyl}phenyl)propanoic acid"	""	"compound (+)-10r [PMID: 26774927]|example 20 [WO2014023643]"	"CCCCCCNC(=O)Oc1cccc(c1)c1ccc(cc1F)[C@@H](C(=O)O)C"	"USQOVYLRWBOSQC-HNNXBMFYSA-N"	"InChI=1S/C22H26FNO4/c1-3-4-5-6-12-24-22(27)28-18-9-7-8-17(13-18)19-11-10-16(14-20(19)23)15(2)21(25)26/h7-11,13-15H,3-6,12H2,1-2H3,(H,24,27)(H,25,26)/t15-/m0/s1"	"yes"	""	""
"8899"	"(<i>S</i>)-liquiritigenin"	""	"Natural product"	""	""	""	""	"310264680"	"114829"	""	""	"CHEMBL252642"	""	""	""	""	"(2S)-7-hydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one"	""	""	"C1[C@H](OC2=C(C1=O)C=CC(=C2)O)C3=CC=C(C=C3)O"	"FURUXTVZLHCCNA-AWEZNQCLSA-N"	"InChI=1S/C15H12O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-7,14,16-17H,8H2/t14-/m0/s1"	"yes"	""	""
"9984"	"ISO-1"	""	"Synthetic organic"	""	""	""	""	"374883871"	"4633677"	""	""	"CHEMBL210858"	""	""	""	""	"methyl 2-[3-(4-oxo-1-cyclohexa-2,5-dienylidene)-1,2-oxazolidin-5-yl]acetate"	""	"IN1228"	"COC(=O)CC1ONC(=C2C=CC(=O)C=C2)C1"	"CLVQGFPQFNASJH-UHFFFAOYSA-N"	"InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,13H,6-7H2,1H3"	"yes"	""	""
"7205"	"isoetarine"	""	"Synthetic organic"	"yes"	""	""	""	"178103780"	"3762"	""	""	"CHEMBL1201213"	""	""	""	""	"4-{1-hydroxy-2-[(propan-2-yl)amino]butyl}benzene-1,2-diol"	"isoetarine"	"Bronkometer&reg;|Bronkosol&reg;|WIN-3406"	"CCC(C(c1ccc(c(c1)O)O)O)NC(C)C"	"HUYWAWARQUIQLE-UHFFFAOYSA-N"	"InChI=1S/C13H21NO3/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9/h5-8,10,13-17H,4H2,1-3H3"	"yes"	""	""
"2899"	"isothiourea-1t"	""	"Synthetic organic"	""	""	""	""	"135650433"	"25147749"	""	""	"CHEMBL460491"	""	""	""	""	"6-dimethyl-5H,6H-imidazo[2,1-b][1,3]thiazol-3-yl}methyl)sulfanyl]methanimidamide"	""	"IT1t"	"CC1(C)N=c2n(C1)c(cs2)CS/C(=N\C1CCCCC1)/NC1CCCCC1"	"OOSUDWRRWZVFEB-UHFFFAOYSA-N"	"InChI=1S/C21H34N4S2/c1-21(2)15-25-18(14-27-20(25)24-21)13-26-19(22-16-9-5-3-6-10-16)23-17-11-7-4-8-12-17/h14,16-17H,3-13,15H2,1-2H3,(H,22,23)"	"yes"	""	""
"9704"	"isunakinra"	""	"Peptide"	""	""	""	""	"348353663"	""	""	""	"CHEMBL3545190"	""	""	""	""	""	"isunakinra"	"EBI-005"	""	""	""	"yes"	""	""
"8364"	"itacitinib"	""	"Synthetic organic"	""	""	""	""	"252166576"	"53380437"	""	""	""	""	""	""	""	"2-[1-[1-[3-fluoro-2-(trifluoromethyl)pyridine-4-carbonyl]piperidin-4-yl]-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile"	"itacitinib"	"Examlpe 294 [WO2011112662]|INCB-039110"	"N#CCC1(CN(C1)C1CCN(CC1)C(=O)c1ccnc(c1F)C(F)(F)F)n1ncc(c1)c1ncnc2c1cc[nH]2"	"KTBSXLIQKWEBRB-UHFFFAOYSA-N"	"InChI=1S/C26H23F4N9O/c27-20-18(1-7-32-22(20)26(28,29)30)24(40)37-9-3-17(4-10-37)38-13-25(14-38,5-6-31)39-12-16(11-36-39)21-19-2-8-33-23(19)35-15-34-21/h1-2,7-8,11-12,15,17H,3-5,9-10,13-14H2,(H,33,34,35)"	"yes"	""	""
"9421"	"itolizumab"	""	"Antibody"	"yes"	""	""	""	"328083521"	""	""	""	""	""	""	""	""	""	"itolizumab"	"Alzumab&reg;|T1h"	""	""	""	"yes"	""	""
"11878"	"ivarmacitinib"	""	"Synthetic organic"	"yes"	""	""	""	"461663434"	"71622431"	""	""	""	""	""	""	""	"(3aS,6aR)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxamide"	"ivarmacitinib"	"Asuda&reg; (China)|example 34 [WO2013091539A1]|SHR-0302|SHR0302"	"CN(C1C[C@@H]2CN(C[C@@H]2C1)C(=O)Nc1nc(ns1)OC)c1ncnc2c1cc[nH]2"	"DNBCBAXDWNDRNO-FOSCPWQOSA-N"	"InChI=1S/C18H22N8O2S/c1-25(15-13-3-4-19-14(13)20-9-21-15)12-5-10-7-26(8-11(10)6-12)18(27)23-17-22-16(28-2)24-29-17/h3-4,9-12H,5-8H2,1-2H3,(H,19,20,21)(H,22,23,24,27)/t10-,11+,12?"	"yes"	""	""
"13396"	"ivonescimab"	""	"Antibody"	"yes"	""	""	""	"496703366"	""	""	""	""	""	""	""	""	""	"ivonescimab"	"AK-112|AK112|Idafang&reg; (China)|SMT-112|SMT112"	""	""	""	"yes"	""	""
"7541"	"ixekizumab"	""	"Antibody"	"yes"	""	""	""	"187051842"	""	""	""	""	""	""	""	""	""	"ixekizumab"	"LY-2439821|LY2439821|Taltz&reg;"	""	""	""	"yes"	""	""
"10458"	"izencitinib"	""	"Synthetic organic"	""	""	""	""	"385612218"	"124090478"	""	""	""	""	""	""	""	"3-[(1R,5S)-3-[[7-[(5-methyl-1H-pyrazol-3-yl)amino]-1,6-naphthyridin-5-yl]amino]-8-azabicyclo[3.2.1]octan-8-yl]propanenitrile"	"izencitinib"	"example 1 [WO2016191524A1]|JNJ-8398|JNJ8398|TD-1473|TD1473"	"N#CCCN1[C@@H]2CC[C@H]1CC(C2)Nc1nc(Nc2n[nH]c(c2)C)cc2c1cccn2"	"DADAEARVGOQWHV-ALOPSCKCSA-N"	"InChI=1S/C22H26N8/c1-14-10-21(29-28-14)26-20-13-19-18(4-2-8-24-19)22(27-20)25-15-11-16-5-6-17(12-15)30(16)9-3-7-23/h2,4,8,10,13,15-17H,3,5-6,9,11-12H2,1H3,(H3,25,26,27,28,29)/t15?,16-,17+"	"yes"	""	""
"10156"	"JAK3 inhibitor 32"	""	"Synthetic organic"	""	""	""	""	"381118866"	"137321159"	""	""	""	""	""	""	""	"N-((1R,3S)-3-Cyanamido-5-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)-3-cyanobenzenesulfonamide"	""	"compound 32 [PMID: 30423248]"	"N#CN[C@H]1C[C@H](c2c1cc(cc2)c1ncnc2c1cc[nH]2)NS(=O)(=O)c1cccc(c1)F"	"MLJSOTTYIVCEQO-VQTJNVASSA-N"	"InChI=1S/C22H17FN6O2S/c23-14-2-1-3-15(9-14)32(30,31)29-20-10-19(26-11-24)18-8-13(4-5-16(18)20)21-17-6-7-25-22(17)28-12-27-21/h1-9,12,19-20,26,29H,10H2,(H,25,27,28)/t19-,20+/m0/s1"	"yes"	""	""
"10157"	"JAK3 inhibitor 34"	""	"Synthetic organic"	""	""	""	""	"381118867"	"137321160"	""	""	""	""	""	""	""	"(S)-N-(6-(5-Phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2,3-dihydro-1H-inden-1-yl)cyanamide"	""	"compound 34 [PMID: 30423248]"	"N#CN[C@H]1CCc2c1cc(cc2)c1ncnc2c1c(c[nH]2)c1ccccc1"	"LOSIDNZHKAVMKF-IBGZPJMESA-N"	"InChI=1S/C22H17N5/c23-12-25-19-9-8-15-6-7-16(10-17(15)19)21-20-18(14-4-2-1-3-5-14)11-24-22(20)27-13-26-21/h1-7,10-11,13,19,25H,8-9H2,(H,24,26,27)/t19-/m0/s1"	"yes"	""	""
"10148"	"JAK inhibitor 17b"	""	"Synthetic organic"	""	""	""	""	"381118858"	"137321156"	""	""	""	""	""	""	""	"4-(Cyclohexylmethyl)-7,8-dimethoxy-1,4-dihydro-5H-benzo[c]pyrrolo[2,3-h][1,6]naphthyridin-5-one"	""	""	"COc1cc2c(=O)n(CC3CCCCC3)c3c(c2cc1OC)cnc1c3cc[nH]1"	"RSFALMGMTQBFJZ-UHFFFAOYSA-N"	"InChI=1S/C23H25N3O3/c1-28-19-10-16-17(11-20(19)29-2)23(27)26(13-14-6-4-3-5-7-14)21-15-8-9-24-22(15)25-12-18(16)21/h8-12,14H,3-7,13H2,1-2H3,(H,24,25)"	"yes"	""	""
"10147"	"JAK inhibitor 20a"	""	"Synthetic organic"	""	""	""	""	"381118857"	"137321155"	""	""	""	""	""	""	""	"(R)-1-(2-(7,8-Dimethoxy-5-oxo-1,5-dihydro-4H-benzo[c]pyrrolo[2,3-h][1,6]naphthyridin-4-yl)butanoyl)azetidine-3-carbonitrile"	""	""	"N#CC1CN(C1)C(=O)[C@H](n1c(=O)c2cc(OC)c(cc2c2c1c1cc[nH]c1nc2)OC)CC"	"ZDNBWZRRFSXDFS-GOSISDBHSA-N"	"InChI=1S/C24H23N5O4/c1-4-18(24(31)28-11-13(9-25)12-28)29-21-14-5-6-26-22(14)27-10-17(21)15-7-19(32-2)20(33-3)8-16(15)23(29)30/h5-8,10,13,18H,4,11-12H2,1-3H3,(H,26,27)/t18-/m1/s1"	"yes"	""	""
"1277"	"JNJ-10191584"	""	"Synthetic organic"	""	""	""	""	"135649827"	"10446295"	""	""	"CHEMBL185951"	""	""	""	""	"(6-chloro-1H-benzimidazol-2-yl)-(4-methylpiperazin-1-yl)methanone"	""	"compound 12|JNJ 10191584|VUF 6002|VUF6002"	"CN1CCN(CC1)C(=O)c1nc2c([nH]1)cc(cc2)Cl"	"MOIWSUQWIOVGRH-UHFFFAOYSA-N"	"InChI=1S/C13H15ClN4O/c1-17-4-6-18(7-5-17)13(19)12-15-10-3-2-9(14)8-11(10)16-12/h2-3,8H,4-7H2,1H3,(H,15,16)"	"yes"	""	""
"6563"	"JNJ-10311795"	""	"Synthetic organic"	""	""	""	""	"178103177"	"10146470"	""	""	"CHEMBL374027"	""	""	""	""	"[2-[3-[methyl-[1-(naphthalene-2-carbonyl)piperidin-4-yl]carbamoyl]naphthalen-2-yl]-1-naphthalen-1-yl-2-oxoethyl]phosphonic acid"	""	""	"OP(=O)(C(c1cccc2c1cccc2)C(=O)c1cc2ccccc2cc1C(=O)N(C1CCN(CC1)C(=O)c1ccc2c(c1)cccc2)C)O"	"XUJQPDQURBZEGJ-UHFFFAOYSA-N"	"InChI=1S/C40H35N2O6P/c1-41(32-19-21-42(22-20-32)39(44)31-18-17-26-9-2-3-11-28(26)23-31)40(45)36-25-30-13-5-4-12-29(30)24-35(36)37(43)38(49(46,47)48)34-16-8-14-27-10-6-7-15-33(27)34/h2-18,23-25,32,38H,19-22H2,1H3,(H2,46,47,48)"	"yes"	""	""
"10586"	"JNJ-27141491"	""	"Synthetic organic"	""	""	""	""	"404859033"	"11617815"	""	""	""	""	""	""	""	"methyl 3-[(1R)-1-(3,4-difluorophenyl)propyl]-5-(1,2-oxazol-5-yl)-2-sulfanylidene-1H-imidazole-4-carboxylate"	""	"JNJ27141491"	"CC[C@@H](n1c(=S)[nH]c(c1C(=O)OC)c1ccno1)c1ccc(c(c1)F)F"	"SYARXICKXVXWNA-GFCCVEGCSA-N"	"InChI=1S/C17H15F2N3O3S/c1-3-12(9-4-5-10(18)11(19)8-9)22-15(16(23)24-2)14(21-17(22)26)13-6-7-20-25-13/h4-8,12H,3H2,1-2H3,(H,21,26)/t12-/m1/s1"	"yes"	""	""
"8984"	"JNJ-39758979"	""	"Synthetic organic"	""	""	""	""	"310264764"	"24994634"	""	""	"CHEMBL3236549"	""	""	""	""	"4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine"	""	"JNJ 39758979|JNJ39758979"	"N[C@@H]1CCN(C1)c1cc(nc(n1)N)C(C)C"	"COOGVHJHSCBOQT-MRVPVSSYSA-N"	"InChI=1S/C11H19N5/c1-7(2)9-5-10(15-11(13)14-9)16-4-3-8(12)6-16/h5,7-8H,3-4,6,12H2,1-2H3,(H2,13,14,15)/t8-/m1/s1"	"yes"	""	""
"5996"	"JNK inhibitor IX"	""	"Synthetic organic"	""	""	""	""	"178102618"	"766949"	""	""	"CHEMBL233001"	""	""	""	""	"N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)naphthalene-1-carboxamide"	""	"AC1LG8KT|BAS 01816608|TCS JNK 5a"	"N#Cc1c(sc2c1CCCC2)NC(=O)c1cccc2c1cccc2"	"WQGDQGAFSDMBLA-UHFFFAOYSA-N"	"InChI=1S/C20H16N2OS/c21-12-17-15-9-3-4-11-18(15)24-20(17)22-19(23)16-10-5-7-13-6-1-2-8-14(13)16/h1-2,5-8,10H,3-4,9,11H2,(H,22,23)"	"yes"	""	""
"10595"	"JR14a"	""	"Synthetic organic"	""	""	""	""	"404859042"	"145996525"	""	""	""	""	""	""	""	"5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride"	""	""	"O=C(c1sc(cc1C)C(c1ccc(cc1)Cl)c1ccc(cc1)Cl)N[C@H](C(=O)O)CCCNC(=N)N"	"OHRIKWUZKGNQKQ-IBGZPJMESA-N"	"InChI=1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1"	"yes"	""	""
"9663"	"KA1010"	""	"Synthetic organic"	""	""	""	""	"348353622"	"46852450"	""	""	"CHEMBL3675757"	""	""	""	""	"7-(dipyridin-2-ylamino)-N-hydroxyheptanamide"	""	""	"ONC(=O)CCCCCCN(c1ccccn1)c1ccccn1"	"QKTORDWLHYWRJF-UHFFFAOYSA-N"	"InChI=1S/C17H22N4O2/c22-17(20-23)11-3-1-2-8-14-21(15-9-4-6-12-18-15)16-10-5-7-13-19-16/h4-7,9-10,12-13,23H,1-3,8,11,14H2,(H,20,22)"	"yes"	""	""
"9691"	"KBP-7018"	""	"Synthetic organic"	""	""	""	""	"348353650"	"136216081"	""	""	""	""	""	""	""	"methyl (3Z)-3-[[[1-(2-morpholin-4-ylacetyl)-2,3-dihydroindol-5-yl]amino]-phenylmethylidene]-2-oxo-1H-indole-6-carboxylate"	""	"compound 3 [Huang <i>et al</i>., 2017]"	"COC(=O)c1ccc2c(c1)NC(=O)/C/2=C(/c1ccccc1)\Nc1ccc2c(c1)CCN2C(=O)CN1CCOCC1"	"JVDJHTYIWQIOCA-ZIADKAODSA-N"	"InChI=1S/C31H30N4O5/c1-39-31(38)22-7-9-24-25(18-22)33-30(37)28(24)29(20-5-3-2-4-6-20)32-23-8-10-26-21(17-23)11-12-35(26)27(36)19-34-13-15-40-16-14-34/h2-10,17-18,32H,11-16,19H2,1H3,(H,33,37)/b29-28-"	"yes"	""	""
"4795"	"ketoprofen"	""	"Synthetic organic"	"yes"	""	""	""	"178101497"	"3825"	""	""	"CHEMBL571"	""	""	""	""	"2-(3-benzoylphenyl)propanoic acid"	"ketoprofen"	"Actron&reg;|Orudis&reg;"	"OC(=O)C(c1cccc(c1)C(=O)c1ccccc1)C"	"DKYWVDODHFEZIM-UHFFFAOYSA-N"	"InChI=1S/C16H14O3/c1-11(16(18)19)13-8-5-9-14(10-13)15(17)12-6-3-2-4-7-12/h2-11H,1H3,(H,18,19)"	"yes"	""	""
"6661"	"ketorolac"	""	"Synthetic organic"	"yes"	""	""	""	"178103273"	"3826"	""	""	"CHEMBL469"	""	""	""	""	"5-(benzoyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid"	"ketorolac"	"Acular&reg;|Toradol&reg;"	"OC(=O)C1CCn2c1ccc2C(=O)c1ccccc1"	"OZWKMVRBQXNZKK-UHFFFAOYSA-N"	"InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)"	"yes"	""	""
"9482"	"KML29"	""	"Synthetic organic"	""	""	""	""	"329968422"	"71656212"	""	""	""	""	""	""	""	"1,1,1,3,3,3-hexafluoropropan-2-yl 4-[bis(1,3-benzodioxol-5-yl)-hydroxymethyl]piperidine-1-carboxylate"	""	""	"O=C(N1CCC(CC1)C(c1ccc2c(c1)OCO2)(c1ccc2c(c1)OCO2)O)OC(C(F)(F)F)C(F)(F)F"	"SXHQLPHDBLTFPM-UHFFFAOYSA-N"	"InChI=1S/C24H21F6NO7/c25-23(26,27)20(24(28,29)30)38-21(32)31-7-5-13(6-8-31)22(33,14-1-3-16-18(9-14)36-11-34-16)15-2-4-17-19(10-15)37-12-35-17/h1-4,9-10,13,20,33H,5-8,11-12H2"	"yes"	""	""
"10245"	"KT-109"	""	"Synthetic organic"	""	""	""	""	"381744927"	"53364540"	""	""	"CHEMBL2144065"	""	""	""	""	""	""	"KT109"	"O=C(N1CCCCC1Cc1ccccc1)n1nnc(c1)c1ccc(cc1)c1ccccc1"	"JKJMWHULJIOKPJ-UHFFFAOYSA-N"	"InChI=1S/C27H26N4O/c32-27(30-18-8-7-13-25(30)19-21-9-3-1-4-10-21)31-20-26(28-29-31)24-16-14-23(15-17-24)22-11-5-2-6-12-22/h1-6,9-12,14-17,20,25H,7-8,13,18-19H2"	"yes"	""	""
"1952"	"L-161,982 (EP<sub>4</sub>A)"	""	"Synthetic organic"	""	""	""	""	"135650237"	"5312129"	""	""	""	""	""	""	""	"N-[2-[4-[[3-butyl-5-oxo-1-[2-(trifluoromethyl)phenyl]-1,2,4-triazol-4-yl]methyl]phenyl]phenyl]sulfonyl-5-methylthiophene-2-carboxamide"	""	"EP4A|L-161982|L161982"	"CCCCc1nn(c(=O)n1Cc1ccc(cc1)c1ccccc1S(=O)(=O)NC(=O)c1ccc(s1)C)c1ccccc1C(F)(F)F"	"JYZLVNVGBRFRME-UHFFFAOYSA-N"	"InChI=1S/C32H29F3N4O4S2/c1-3-4-13-29-36-39(26-11-7-6-10-25(26)32(33,34)35)31(41)38(29)20-22-15-17-23(18-16-22)24-9-5-8-12-28(24)45(42,43)37-30(40)27-19-14-21(2)44-27/h5-12,14-19H,3-4,13,20H2,1-2H3,(H,37,40)"	"yes"	""	""
"9027"	"L6H21"	""	"Synthetic organic"	""	""	""	""	"315661112"	"5346378"	""	""	"CHEMBL2013139"	""	""	""	""	"(E)-3-(2,3-dimethoxyphenyl)-1-(4-methoxyphenyl)prop-2-en-1-one"	""	""	"COc1ccc(cc1)C(=O)/C=C/c1cccc(c1OC)OC"	"IECVLMVZGCYCSZ-FMIVXFBMSA-N"	"InChI=1S/C18H18O4/c1-20-15-10-7-13(8-11-15)16(19)12-9-14-5-4-6-17(21-2)18(14)22-3/h4-12H,1-3H3/b12-9+"	"yes"	""	""
"1941"	"L-798,106"	""	"Synthetic organic"	""	""	""	""	"135650500"	"15551229"	""	""	"CHEMBL218071"	""	""	""	""	"(E)-N-(5-bromo-2-methoxyphenyl)sulfonyl-3-[2-(naphthalen-2-ylmethyl)phenyl]prop-2-enamide"	""	"L-798106|L798106"	"COc1ccc(cc1S(=O)(=O)NC(=O)/C=C/c1ccccc1Cc1ccc2c(c1)cccc2)Br"	"ODTKFNUPVBULRJ-NTCAYCPXSA-N"	"InChI=1S/C27H22BrNO4S/c1-33-25-14-13-24(28)18-26(25)34(31,32)29-27(30)15-12-21-7-3-5-9-23(21)17-19-10-11-20-6-2-4-8-22(20)16-19/h2-16,18H,17H2,1H3,(H,29,30)/b15-12+"	"yes"	""	""
"12870"	"labuxtinib"	""	"Synthetic organic"	""	""	""	""	"485205991"	"71280305"	""	""	"CHEMBL3962292"	""	""	""	""	"N-[5-[5-[(1R,2S)-2-fluorocyclopropyl]-1,2,4-oxadiazol-3-yl]-2-methylphenyl]imidazo[1,2-a]pyridine-3-carboxamide"	"labuxtinib"	"Compound 1 [WO2022109595]|example F91 [WO2013033070]|THB-335|THB335"	"F[C@@H]1[C@H](C1)C2=NC(=NO2)C=3C=CC(=C(C3)NC(=O)C4=CN=C5N4C=CC=C5)C"	"RHNJOZCVGSBEAG-KBPBESRZSA-N"	"InChI=1S/C20H16FN5O2/c1-11-5-6-12(18-24-20(28-25-18)13-9-14(13)21)8-15(11)23-19(27)16-10-22-17-4-2-3-7-26(16)17/h2-8,10,13-14H,9H2,1H3,(H,23,27)/t13-,14-/m0/s1"	"yes"	""	""
"9764"	"lanraplenib"	""	"Synthetic organic"	""	""	""	""	"354702237"	"118161062"	""	""	""	""	""	""	""	"6-(6-aminopyrazin-2-yl)-N-[4-[4-(oxetan-3-yl)piperazin-1-yl]phenyl]imidazo[1,2-a]pyrazin-8-amine"	"lanraplenib"	"compound 39 [PMID: 32292557]|Ex.-2, US9290505|example 2 [US9290505]|GS-9876|GS9876"	"Nc1cncc(n1)c1cn2ccnc2c(n1)Nc1ccc(cc1)N1CCN(CC1)C1COC1"	"XCIGZBVOUQVIPI-UHFFFAOYSA-N"	"InChI=1S/C23H25N9O/c24-21-12-25-11-19(28-21)20-13-32-6-5-26-23(32)22(29-20)27-16-1-3-17(4-2-16)30-7-9-31(10-8-30)18-14-33-15-18/h1-6,11-13,18H,7-10,14-15H2,(H2,24,28)(H,27,29)"	"yes"	""	""
"11143"	"Large proline-rich protein BAG6"	""	"Peptide"	""	""	""	""	"434122203"	""	""	""	""	""	""	""	""	""	""	"BAG6"	""	""	""	"yes"	""	""
"11066"	"LASSBio-1524"	""	"Synthetic organic"	""	""	""	""	"405560507"	"52915756"	""	""	"CHEMBL1760505"	""	""	""	""	"N-[(E)-(4-nitrophenyl)methylideneamino]naphthalene-2-carboxamide"	""	""	"O=C(c1ccc2c(c1)cccc2)N/N=C/c1ccc(cc1)[N+](=O)[O-]"	"RUQCGNRXDVIDAJ-XDHOZWIPSA-N"	"InChI=1S/C18H13N3O3/c22-18(16-8-7-14-3-1-2-4-15(14)11-16)20-19-12-13-5-9-17(10-6-13)21(23)24/h1-12H,(H,20,22)/b19-12+"	"yes"	""	""
"10527"	"LASW1393"	""	"Synthetic organic"	""	""	""	""	"387065609"	"71062030"	""	""	""	""	""	""	""	"2-[(1r,4r)-4-{8-oxo-2-[(2-oxo-1,2-dihydropyridin-3-yl)amino]-8,9-dihydro-7H-purin-9-yl}cyclohexyl]acetonitrile"	""	"compound 34 [PMID: 31609613]|LASW-1393"	"N#CC[C@@H]1CC[C@H](CC1)n1c(=O)[nH]c2c1nc(nc2)Nc1ccc[nH]c1=O"	"NIIBPFADTOPKBI-HAQNSBGRSA-N"	"InChI=1S/C18H19N7O2/c19-8-7-11-3-5-12(6-4-11)25-15-14(23-18(25)27)10-21-17(24-15)22-13-2-1-9-20-16(13)26/h1-2,9-12H,3-7H2,(H,20,26)(H,23,27)(H,21,22,24)/t11-,12-"	"yes"	""	""
"10653"	"lazucirnon"	""	"Synthetic organic"	""	""	""	""	"404859100"	"59534386"	""	""	"CHEMBL3670800"	""	""	""	""	"2-[[(2R)-1-[1-[(4-chloro-3-methylphenyl)methyl]piperidin-4-yl]-5-oxopyrrolidine-2-carbonyl]amino]-N,N,6-trimethylpyridine-4-carboxamide"	"lazucirnon"	"AKST-4290|AKST4290|ALK-4290|ALK4290|Example 11 [WO2012045803A1]"	"O=C([C@H]1CCC(=O)N1C1CCN(CC1)Cc1ccc(c(c1)C)Cl)Nc1nc(C)cc(c1)C(=O)N(C)C"	"DWKNOLCXIFYNFV-HSZRJFAPSA-N"	"InChI=1S/C27H34ClN5O3/c1-17-13-19(5-6-22(17)28)16-32-11-9-21(10-12-32)33-23(7-8-25(33)34)26(35)30-24-15-20(14-18(2)29-24)27(36)31(3)4/h5-6,13-15,21,23H,7-12,16H2,1-4H3,(H,29,30,35)/t23-/m1/s1"	"yes"	""	""
"7684"	"lebrikizumab"	""	"Antibody"	"yes"	""	""	""	"223366019"	""	""	""	""	""	""	""	""	""	"lebrikizumab"	"Ebglyss&reg;|lebrikizumab-lbkz|MILR1444A|RG3637|TNX-650"	""	""	""	"yes"	""	""
"6825"	"leflunomide"	""	"Synthetic organic"	"yes"	""	""	""	"178103431"	"3899"	""	""	"CHEMBL960"	""	""	""	""	"5-methyl-N-[4-(trifluoromethyl)phenyl]-1,2-oxazole-4-carboxamide"	"leflunomide"	"Arabloc&reg;|Arava&reg;|HWA 486|HWA-486|lefunamide|SU-101"	"O=C(c1cnoc1C)Nc1ccc(cc1)C(F)(F)F"	"VHOGYURTWQBHIL-UHFFFAOYSA-N"	"InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)"	"yes"	""	""
"9772"	"lenabasum"	""	"Synthetic organic"	""	""	""	""	"354702245"	"3083542"	""	""	"CHEMBL456341"	""	""	""	""	"(6aR,10aR)-1-hydroxy-6,6-dimethyl-3-(2-methyloctan-2-yl)-6a,7,10,10a-tetrahydrobenzo[c]chromene-9-carboxylic acid"	"lenabasum"	"ajulemic acid|CPL-7075|CPL7075|CT-3|IP-751|IP751"	"CCCCCCC(c1cc(O)c2c(c1)OC([C@H]1[C@H]2CC(=CC1)C(=O)O)(C)C)(C)C"	"YCHYFHOSGQABSW-RTBURBONSA-N"	"InChI=1S/C25H36O4/c1-6-7-8-9-12-24(2,3)17-14-20(26)22-18-13-16(23(27)28)10-11-19(18)25(4,5)29-21(22)15-17/h10,14-15,18-19,26H,6-9,11-13H2,1-5H3,(H,27,28)/t18-,19-/m1/s1"	"yes"	""	""
"7331"	"lenalidomide"	""	"Synthetic organic"	"yes"	""	""	""	"178103903"	"216326"	""	""	"CHEMBL848"	""	""	""	""	"4-amino-2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindol-1-one"	"lenalidomide"	"CC-5013|CDC-501|Revlimid&reg;"	"OC1=NC(=O)C(CC1)N1Cc2c(C1=O)cccc2N"	"GOTYRUGSSMKFNF-UHFFFAOYSA-N"	"InChI=1S/C13H13N3O3/c14-9-3-1-2-7-8(9)6-16(13(7)19)10-4-5-11(17)15-12(10)18/h1-3,10H,4-6,14H2,(H,15,17,18)"	"yes"	""	""
"9424"	"leniolisib"	""	"Synthetic organic"	"yes"	""	""	""	"328083524"	"57495353"	""	""	"CHEMBL3643413"	""	""	""	""	"1-[(3S)-3-[[6-[6-methoxy-5-(trifluoromethyl)pyridin-3-yl]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-4-yl]amino]pyrrolidin-1-yl]propan-1-one"	"leniolisib"	"CDZ-173|CDZ173|Example 67 [WO2012004299]|Joenja&reg;"	"CCC(=O)N1CC[C@@H](C1)Nc1ncnc2c1CN(CC2)c1cnc(c(c1)C(F)(F)F)OC"	"MWKYMZXCGYXLPL-ZDUSSCGKSA-N"	"InChI=1S/C21H25F3N6O2/c1-3-18(31)30-6-4-13(10-30)28-19-15-11-29(7-5-17(15)26-12-27-19)14-8-16(21(22,23)24)20(32-2)25-9-14/h8-9,12-13H,3-7,10-11H2,1-2H3,(H,26,27,28)/t13-/m0/s1"	"yes"	""	""
"8935"	"lenzilumab"	""	"Antibody"	""	""	""	""	"310264716"	""	""	""	""	""	""	""	""	""	"lenzilumab"	"KB-003|KB003"	""	""	""	"yes"	""	""
"11901"	"LEO 134310"	""	"Synthetic organic"	""	""	""	""	"461663456"	"126714060"	""	""	""	""	""	""	""	"[(3S)-1-[(3R)-5-oxooxolane-3-carbonyl]piperidin-3-yl] 4-[(1R,2S)-1-(4-cyclopropylphenyl)-2-[[(2R)-oxolane-2-carbonyl]amino]propoxy]benzoate"	""	"LEO-134310|LEO134310"	"C[C@H](NC(=O)[C@H]1CCCO1)[C@H](Oc1ccc(cc1)C(=O)O[C@H]1CCCN(C1)C(=O)[C@H]1COC(=O)C1)c1ccc(cc1)C1CC1"	"NADMBBGHEQYUMJ-WDXNIXBWSA-N"	"InChI=1S/C34H40N2O8/c1-21(35-32(38)29-5-3-17-41-29)31(24-10-8-23(9-11-24)22-6-7-22)43-27-14-12-25(13-15-27)34(40)44-28-4-2-16-36(19-28)33(39)26-18-30(37)42-20-26/h8-15,21-22,26,28-29,31H,2-7,16-20H2,1H3,(H,35,38)/t21-,26+,28-,29+,31-/m0/s1"	"yes"	""	""
"12725"	"LEO 239652"	""	"Synthetic organic"	""	""	""	""	"483123273"	"71611998"	""	""	"CHEMBL4747201"	""	""	""	""	"2-methylpropyl 1-[8-methoxy-5-(1-oxo-3H-2-benzofuran-5-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropane-1-carboxylate"	""	"compound 40 [PMID: 33054196]|LEO-239652|LEO239652"	"O=C1OCC2=C1C=CC(=C2)C=3N4C(=NC(C5(CC5)C(OCC(C)C)=O)=N4)C(=CC3)OC"	"LUUUHUYQTLUIDG-UHFFFAOYSA-N"	"InChI=1S/C23H23N3O5/c1-13(2)11-31-22(28)23(8-9-23)21-24-19-18(29-3)7-6-17(26(19)25-21)14-4-5-16-15(10-14)12-30-20(16)27/h4-7,10,13H,8-9,11-12H2,1-3H3"	"yes"	""	""
"12724"	"LEO 29102"	""	"Synthetic organic"	""	""	""	""	"483123272"	"66829720"	""	""	"CHEMBL3315088"	""	""	""	""	"2-[6-[2-(3,5-dichloropyridin-4-yl)acetyl]-2,3-dimethoxyphenoxy]-N-propylacetamide"	""	"compound 20 [PMID: 24984230]|LEO-29102|LEO29102"	"O=C(C1=C(OCC(NCCC)=O)C(OC)=C(C=C1)OC)CC2=C(Cl)C=NC=C2Cl"	"HOKIHKLKOZWCRY-UHFFFAOYSA-N"	"InChI=1S/C20H22Cl2N2O5/c1-4-7-24-18(26)11-29-19-12(5-6-17(27-2)20(19)28-3)16(25)8-13-14(21)9-23-10-15(13)22/h5-6,9-10H,4,7-8,11H2,1-3H3,(H,24,26)"	"yes"	""	""
"12871"	"lepzacitinib"	""	"Synthetic organic"	""	""	""	""	"485205992"	"138624627"	""	""	""	""	""	""	""	"ethyl 4-[[(3R)-1-(2-cyanoacetyl)piperidin-3-yl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxylate"	""	"example 117 [WO2019090158A1]"	"C(#N)CC(=O)N1C[C@@H](CCC1)NC2=C3C(=NC=C2C(=O)OCC)NC=C3"	"QQOPOYMFJLUSBI-GFCCVEGCSA-N"	"InChI=1S/C18H21N5O3/c1-2-26-18(25)14-10-21-17-13(6-8-20-17)16(14)22-12-4-3-9-23(11-12)15(24)5-7-19/h6,8,10,12H,2-5,9,11H2,1H3,(H2,20,21,22)/t12-/m1/s1"	"yes"	""	""
"10752"	"leronlimab"	""	"Antibody"	""	""	""	""	"405560193"	""	""	""	""	""	""	""	""	""	"leronlimab"	"PRO 140|PRO-140|PRO140|Vyrologix&reg;"	""	""	""	"yes"	""	""
"5672"	"lestaurtinib"	""	"Synthetic organic"	""	""	""	""	"178102300"	"126565"	""	""	"CHEMBL603469"	""	""	""	""	"(15S,16S,18R)-16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8,10,12,20,22,24-nonaen-3-one"	"lestaurtinib"	"CEP-701|KT-5555|SP924"	"OC[C@@]1(O)C[C@H]2O[C@]1(C)n1c3c4n2c2ccccc2c4c2c(c3c3c1cccc3)CNC2=O"	"UIARLYUEJFELEN-LROUJFHJSA-N"	"InChI=1S/C26H21N3O4/c1-25-26(32,12-30)10-18(33-25)28-16-8-4-2-6-13(16)20-21-15(11-27-24(21)31)19-14-7-3-5-9-17(14)29(25)23(19)22(20)28/h2-9,18,30,32H,10-12H2,1H3,(H,27,31)/t18-,25+,26+/m1/s1"	"yes"	""	""
"9816"	"levosalbutamol"	""	"Synthetic organic"	"yes"	""	""	""	"354702288"	"123600"	""	""	"CHEMBL1002"	""	""	""	""	"4-[(1R)-2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol"	"levosalbutamol"	"(-)-albuterol|(-)-salbutamol|(R)-salbutamol|levalbuterol|Xopenex&reg;"	"OCc1cc(ccc1O)[C@H](CNC(C)(C)C)O"	"NDAUXUAQIAJITI-LBPRGKRZSA-N"	"InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3/t12-/m0/s1"	"yes"	""	""
"9262"	"LFM-A13"	""	"Synthetic organic"	""	""	""	""	"315661337"	"54676905"	""	""	""	""	""	""	""	"(Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide"	""	"&alpha;-cyano-beta-hydroxy-&beta;-methyl-N-(2, 5-dibromophenyl)propenamide|alpha-cyano-beta-hydroxy-beta-methyl-N-(2, 5-dibromophenyl)propenamide"	"C/C(=C(/C(=O)Nc1cc(Br)ccc1Br)\C#N)/O"	"UVSVTDVJQAJIFG-VURMDHGXSA-N"	"InChI=1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-"	"yes"	""	""
"9298"	"LHVS"	""	"Synthetic organic"	""	""	""	""	"318164817"	"23648296"	""	""	"CHEMBL222649"	""	""	""	""	"N-[(2R)-4-methyl-1-oxo-1-[[(E,3R)-5-phenyl-1-phenylsulfonylpent-1-en-3-yl]amino]pentan-2-yl]morpholine-4-carboxamide"	""	"morpholinurea-leucine-homophenylalanine-vinylsulfone-phenyl|morpholinurea-leucine-homophenylalaninevinyl phenyl sulfone"	"CC(C[C@H](C(=O)N[C@@H](/C=C/S(=O)(=O)c1ccccc1)CCc1ccccc1)NC(=O)N1CCOCC1)C"	"YUMYYTORLYHUFW-ZUDLOMHPSA-N"	"InChI=1S/C28H37N3O5S/c1-22(2)21-26(30-28(33)31-16-18-36-19-17-31)27(32)29-24(14-13-23-9-5-3-6-10-23)15-20-37(34,35)25-11-7-4-8-12-25/h3-12,15,20,22,24,26H,13-14,16-19,21H2,1-2H3,(H,29,32)(H,30,33)/b20-15+/t24-,26-/m1/s1"	"yes"	""	""
"5016"	"LIF"	"Human"	"Peptide"	""	""	""	""	"178101713"	""	"P15018"	"ENSG00000128342"	""	""	""	""	""	""	""	"cholinergic differentiation factor (CDF)|differentiation-inducing factor (DIF)|human interleukin in DA cells (HILDA)"	""	""	""	"yes"	""	""
"7533"	"lifitegrast"	""	"Synthetic organic"	"yes"	""	""	""	"187051834"	"11965427"	""	""	"CHEMBL2048028"	""	""	""	""	"(2S)-2-[[2-(1-benzofuran-6-carbonyl)-5,7-dichloro3,4-dihydro-1H-isoquinoline-6-carbonyl]amino]-3-(3-methylsulfonylphenyl)propanoic acid"	"lifitegrast"	"compound 1g [PMID: 24900456]|SAR 1118|SAR-1118|SAR-1118-023|Xiidra&reg;"	"OC(=O)[C@@H](NC(=O)c1c(Cl)cc2c(c1Cl)CCN(C2)C(=O)c1ccc2c(c1)occ2)Cc1cccc(c1)S(=O)(=O)C"	"JFOZKMSJYSPYLN-QHCPKHFHSA-N"	"InChI=1S/C29H24Cl2N2O7S/c1-41(38,39)20-4-2-3-16(11-20)12-23(29(36)37)32-27(34)25-22(30)13-19-15-33(9-7-21(19)26(25)31)28(35)18-6-5-17-8-10-40-24(17)14-18/h2-6,8,10-11,13-14,23H,7,9,12,15H2,1H3,(H,32,34)(H,36,37)/t23-/m0/s1"	"yes"	""	""
"8997"	"ligelizumab"	""	"Antibody"	""	""	""	""	"310264775"	""	""	""	""	""	""	""	""	""	"ligelizumab"	"CL-2C|NVP-QGE031|QGE031"	""	""	""	"yes"	""	""
"5070"	"LIGHT"	"Human"	"Peptide"	""	""	""	""	"178101763"	""	"O43557"	"ENSG00000125735"	""	""	""	""	""	""	""	"Herpesvirus entry mediator-ligand|TR2"	""	""	""	"yes"	""	""
"13887"	"ligufalimab"	""	"Antibody"	""	""	""	""	"513757572"	""	""	""	""	""	""	""	""	""	"ligufalimab"	"AK-117|AK117"	""	""	""	"yes"	""	""
"9950"	"lilotomab"	""	"Antibody"	""	""	""	""	"374883837"	""	""	""	""	""	""	""	""	""	"lilotomab"	"Betalutin&reg;|HH1|tetulomab"	""	""	""	"yes"	""	""
"9707"	"linrodostat"	""	"Synthetic organic"	""	""	""	""	"348353666"	"121328278"	""	""	""	""	""	""	""	"(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide"	"linrodostat"	"BMS-986205|BMS986205|Compound 2 [PMID: 29531094]|Example 19 [US20160137652A1]"	"Clc1ccc(cc1)NC(=O)[C@@H](C1CCC(CC1)c1ccnc2c1cc(F)cc2)C"	"KRTIYQIPSAGSBP-KLAILNCOSA-N"	"InChI=1S/C24H24ClFN2O/c1-15(24(29)28-20-9-6-18(25)7-10-20)16-2-4-17(5-3-16)21-12-13-27-23-11-8-19(26)14-22(21)23/h6-17H,2-5H2,1H3,(H,28,29)/t15-,16?,17?/m1/s1"	"yes"	""	""
"7983"	"lintuzumab"	""	"Antibody"	""	""	""	""	"249565664"	""	""	""	""	""	""	""	""	""	"lintuzumab"	"ACTIMAB&reg;|HuM195|SGN-33|SMART M195"	""	""	""	"yes"	""	""
"9310"	"lirilumab"	""	"Antibody"	""	""	""	""	"318164829"	""	""	""	""	""	""	""	""	""	"lirilumab"	"1-7F9|BMS-986015|IPH2102"	""	""	""	"yes"	""	""
"9225"	"lisofylline"	""	"Synthetic organic"	""	""	""	""	"315661300"	"501254"	""	""	"CHEMBL1411"	""	""	""	""	"1-[(5R)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione"	"lisofylline"	"(R)-lisophylline|CT-1501R"	"C[C@H](CCCCn1c(=O)c2n(C)cnc2n(c1=O)C)O"	"NSMXQKNUPPXBRG-SECBINFHSA-N"	"InChI=1S/C13H20N4O3/c1-9(18)6-4-5-7-17-12(19)10-11(14-8-15(10)2)16(3)13(17)20/h8-9,18H,4-7H2,1-3H3/t9-/m1/s1"	"yes"	""	""
"10075"	"LIT-927"	""	"Synthetic organic"	""	""	""	""	"375973262"	"137287575"	""	""	""	""	""	""	""	"4-(4-Chlorophenyl)-6-(4-hydroxy-3-methoxyphenyl)pyrimidin-2(1H)-one"	""	"compound 57 [PMID: 30106292]"	"COc1cc(ccc1O)c1[nH]c(=O)nc(c1)c1ccc(cc1)Cl"	"BYYRNPIGDRRGLJ-UHFFFAOYSA-N"	"InChI=1S/C17H13ClN2O3/c1-23-16-8-11(4-7-15(16)21)14-9-13(19-17(22)20-14)10-2-5-12(18)6-3-10/h2-9,21H,1H3,(H,19,20,22)"	"yes"	""	""
"11122"	"litifilimab"	""	"Antibody"	""	""	""	""	"434122182"	""	""	""	""	""	""	""	""	""	"litifilimab"	"BIIB-059|BIIB059"	""	""	""	"yes"	""	""
"9734"	"liver enriched antimicrobial peptide 2"	"Human"	"Peptide"	""	""	""	""	"354702210"	""	"Q969E1"	"ENSG00000164406"	""	""	""	""	""	""	""	"LEAP2"	""	""	""	"yes"	""	""
"5527"	"LL-37"	"Human"	"Peptide"	""	""	""	""	"178102170"	"134611881"	"P49913"	"ENSG00000164047"	"CHEMBL530345"	""	""	""	""	""	""	"antibacterial protein LL-37|cathelicidin LL 37 (human)"	"NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)CCC(=O)O)[C@H](O)C)CCCN=C(N)N)C(C)C)CC(C)C)CC(=O)N)CCCN=C(N)N)CC(C)C)Cc1ccccc1)CC(=O)O)CCCCN)[C@H](CC)C)CCCN=C(N)N)CCC(=O)N)C(C)C)[C@H](CC)C)CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(C)C)N)CC(C)C)CC(=O)O)Cc1ccccc1)Cc1ccccc1)CCCN=C(N)N)CCCCN)CO)CCCCN)CCC(=O)O)CCCCN)CCCCN)CCC(=O)O)Cc1ccccc1"	"POIUWJQBRNEFGX-XAMSXPGMSA-N"	"InChI=1S/C205H340N60O53/c1-20-114(16)162(261-179(296)128(66-40-46-86-211)235-176(293)135(74-78-155(273)274)243-170(287)125(63-37-43-83-208)241-192(309)148(106-266)257-174(291)126(64-38-44-84-209)234-171(288)129(67-47-87-225-201(215)216)240-185(302)142(98-119-55-29-24-30-56-119)252-187(304)144(100-121-59-33-26-34-60-121)253-189(306)146(102-158(279)280)233-154(272)104-230-167(284)138(94-109(6)7)248-166(283)122(212)93-108(4)5)194(311)231-105-153(271)232-123(61-35-41-81-206)168(285)242-136(75-79-156(275)276)177(294)251-141(97-118-53-27-23-28-54-118)184(301)238-124(62-36-42-82-207)169(286)236-131(69-49-89-227-203(219)220)181(298)263-164(116(18)22-3)197(314)259-160(112(12)13)195(312)246-134(73-77-151(213)269)175(292)237-132(70-50-90-228-204(221)222)180(297)262-163(115(17)21-2)196(313)245-127(65-39-45-85-210)172(289)256-147(103-159(281)282)190(307)254-143(99-120-57-31-25-32-58-120)186(303)249-139(95-110(8)9)183(300)239-130(68-48-88-226-202(217)218)173(290)255-145(101-152(214)270)188(305)250-140(96-111(10)11)191(308)260-161(113(14)15)199(316)265-92-52-72-150(265)193(310)244-133(71-51-91-229-205(223)224)182(299)264-165(117(19)268)198(315)247-137(76-80-157(277)278)178(295)258-149(107-267)200(317)318/h23-34,53-60,108-117,122-150,160-165,266-268H,20-22,35-52,61-107,206-212H2,1-19H3,(H2,213,269)(H2,214,270)(H,230,284)(H,231,311)(H,232,271)(H,233,272)(H,234,288)(H,235,293)(H,236,286)(H,237,292)(H,238,301)(H,239,300)(H,240,302)(H,241,309)(H,242,285)(H,243,287)(H,244,310)(H,245,313)(H,246,312)(H,247,315)(H,248,283)(H,249,303)(H,250,305)(H,251,294)(H,252,304)(H,253,306)(H,254,307)(H,255,290)(H,256,289)(H,257,291)(H,258,295)(H,259,314)(H,260,308)(H,261,296)(H,262,297)(H,263,298)(H,264,299)(H,273,274)(H,275,276)(H,277,278)(H,279,280)(H,281,282)(H,317,318)(H4,215,216,225)(H4,217,218,226)(H4,219,220,227)(H4,221,222,228)(H4,223,224,229)/t114-,115-,116-,117+,122-,123-,124-,125-,126-,127-,128-,129-,130-,131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,144-,145-,146-,147-,148-,149-,150-,160-,161-,162-,163-,164-,165-/m0/s1"	"yes"	""	"yes"
"9016"	"LM10"	""	"Synthetic organic"	""	""	""	""	"315661101"	"135743630"	""	""	"CHEMBL1812545"	""	""	""	""	"6-fluoro-3-[(E)-2-(1H-1,2,3,4-tetrazol-5-yl)ethenyl]-1H-indole"	""	"LM-10"	"Fc1ccc2c(c1)[nH]cc2/C=C/c1nnn[nH]1"	"JDBSZVDIUIRSDG-DAFODLJHSA-N"	"InChI=1S/C11H8FN5/c12-8-2-3-9-7(6-13-10(9)5-8)1-4-11-14-16-17-15-11/h1-6,13H,(H,14,15,16,17)/b4-1+"	"yes"	""	""
"9743"	"lodoxamide"	""	"Synthetic organic"	"yes"	""	""	""	"354702216"	"44564"	""	""	"CHEMBL1201266"	""	""	""	""	"2-[[2-chloro-5-cyano-3-(oxaloamino)phenyl]amino]-2-oxoacetic acid"	"lodoxamide"	"Alomide&reg;"	"N#Cc1cc(NC(=O)C(=O)O)c(c(c1)NC(=O)C(=O)O)Cl"	"RVGLGHVJXCETIO-UHFFFAOYSA-N"	"InChI=1S/C11H6ClN3O6/c12-7-5(14-8(16)10(18)19)1-4(3-13)2-6(7)15-9(17)11(20)21/h1-2H,(H,14,16)(H,15,17)(H,18,19)(H,20,21)"	"yes"	""	""
"13210"	"lomedeucitinib"	""	"Synthetic organic"	""	""	""	""	"491299992"	"138620496"	""	""	""	""	""	""	""	"4-[(3-methylsulfonylpyridin-2-yl)amino]-6-[[(2R)-spiro[2.2]pentane-2-carbonyl]amino]-N-(trideuteriomethyl)pyridazine-3-carboxamide"	"lomedeucitinib"	"BMS-986322|BMS986322|example 252 [US20210253554]"	"CS(=O)(=O)C=1C(=NC=CC1)NC2=C(N=NC(=C2)NC(=O)[C@@H]3CC34CC4)C(=O)NC([2H])([2H])[2H]"	"VWIVBQZLVAGLMH-ASGODXDTSA-N"	"InChI=1S/C18H20N6O4S/c1-19-17(26)14-11(21-15-12(29(2,27)28)4-3-7-20-15)8-13(23-24-14)22-16(25)10-9-18(10)5-6-18/h3-4,7-8,10H,5-6,9H2,1-2H3,(H,19,26)(H2,20,21,22,23,25)/t10-/m0/s1/i1D3"	"yes"	""	""
"11716"	"londamocitinib"	""	"Synthetic organic"	""	""	""	""	"458923751"	"135240395"	""	""	"CHEMBL4447181"	""	""	""	""	"(2R)-N-[3-[5-fluoro-2-(2-fluoro-3-methylsulfonylanilino)pyrimidin-4-yl]-1H-indol-7-yl]-3-methoxy-2-(4-methylpiperazin-1-yl)propanamide"	""	"AZD-4604|AZD4604|example 35 [WO2018134213A1]|Jak1-IN-7"	"COC[C@@H](N1CCN(C)CC1)C(=O)Nc1cccc2c1[nH]cc2c1c(F)cnc(Nc2c(F)c(ccc2)S(=O)(=O)C)n1"	"JNUZADQZHYFJGW-JOCHJYFZSA-N"	"InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14-31-26(17)21)25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1"	"yes"	""	""
"11275"	"lonodelestat"	""	"Synthetic organic"	""	""	""	""	"434321710"	"71532754"	""	""	""	""	""	""	""	""	"lonodelestat"	"cyclo[Ala-Ser-Ile-Pro-Pro-Gln-Lys-Tyr-D-Pro-Pro-Nle(Bu)-Glu-Thr]|POL-6014|POL6014"	"NCCCC[C@@H]1NC(=O)[C@H](CCC(=O)N)NC(=O)[C@@H]2CCCN2C(=O)[C@@H]2CCCN2C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H]3N(C(=O)[C@@H](NC1=O)Cc1ccc(cc1)O)CCC3)CCC2)CCCCCCCC)CCC(=O)O)[C@H](O)C)[C@H](CC)C"	"JMWYNUHGKFJVIB-QGFXQWJDSA-N"	"InChI=1S/C71H111N15O19/c1-6-8-9-10-11-12-19-46-60(94)76-48(30-32-56(91)92)63(97)82-58(42(5)88)67(101)74-41(4)59(93)80-50(39-87)64(98)81-57(40(3)7-2)71(105)86-37-18-24-54(86)70(104)84-35-16-22-52(84)66(100)78-47(29-31-55(73)90)62(96)75-45(20-13-14-33-72)61(95)79-49(38-43-25-27-44(89)28-26-43)68(102)85-36-17-23-53(85)69(103)83-34-15-21-51(83)65(99)77-46/h25-28,40-42,45-54,57-58,87-89H,6-24,29-39,72H2,1-5H3,(H2,73,90)(H,74,101)(H,75,96)(H,76,94)(H,77,99)(H,78,100)(H,79,95)(H,80,93)(H,81,98)(H,82,97)(H,91,92)/t40-,41-,42+,45-,46-,47-,48-,49-,50-,51-,52-,53+,54-,57-,58-/m0/s1"	"yes"	""	""
"7216"	"loratadine"	""	"Synthetic organic"	"yes"	""	""	""	"178103791"	"3957"	""	""	"CHEMBL998"	""	""	""	""	"ethyl 4-(8-chloro-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridin-11-ylidene)piperidine-1-carboxylate"	"loratadine"	"Claritin&reg;|SCH-29851"	"CCOC(=O)N1CCC(=C2c3ccc(cc3CCc3c2nccc3)Cl)CC1"	"JCCNYMKQOSZNPW-UHFFFAOYSA-N"	"InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3"	"yes"	""	""
"9620"	"lorecivivint"	""	"Synthetic organic"	""	""	""	""	"340590250"	"135565709"	""	""	""	""	""	""	""	"N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3-methylbutanamide"	"lorecivivint"	"adavivint (deprecated INN)|SM0-4690|SM04690"	"CC(CC(=O)Nc1cncc(c1)c1ccc2c(c1)c(n[nH]2)c1nc2c([nH]1)c(cnc2)c1cccc(c1)F)C"	"AQDWDWAYVBQMAM-UHFFFAOYSA-N"	"InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28(37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)"	"yes"	""	""
"14407"	"lorigerlimab"	""	"Antibody"	""	""	""	""	"523352199"	""	""	""	""	""	""	""	""	""	"lorigerlimab"	"MGD-019|MGD019"	""	""	""	"yes"	""	""
"7835"	"losmapimod"	""	"Synthetic organic"	""	""	""	""	"223366166"	"11552706"	""	""	"CHEMBL1088752"	""	""	""	""	"6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide"	"losmapimod"	"GS856553|GW856553"	"O=C(c1ccc(nc1)c1cc(cc(c1C)F)C(=O)NC1CC1)NCC(C)(C)C"	"KKYABQBFGDZVNQ-UHFFFAOYSA-N"	"InChI=1S/C22H26FN3O2/c1-13-17(9-15(10-18(13)23)21(28)26-16-6-7-16)19-8-5-14(11-24-19)20(27)25-12-22(2,3)4/h5,8-11,16H,6-7,12H2,1-4H3,(H,25,27)(H,26,28)"	"yes"	""	""
"7085"	"loteprednol etabonate"	""	"Metabolite"	"yes"	""	""	""	"178103663"	"444025"	""	""	"CHEMBL1200865"	""	""	""	""	"chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate"	"loteprednol"	"HGP-1|Inveltys&reg;|Lotemax&reg;|P-5604"	"ClCOC(=O)[C@]1(CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C)OC(=O)OCC"	"DMKSVUSAATWOCU-HROMYWEYSA-N"	"InChI=1S/C24H31ClO7/c1-4-30-21(29)32-24(20(28)31-13-25)10-8-17-16-6-5-14-11-15(26)7-9-22(14,2)19(16)18(27)12-23(17,24)3/h7,9,11,16-19,27H,4-6,8,10,12-13H2,1-3H3/t16-,17-,18-,19+,22-,23-,24-/m0/s1"	"yes"	""	""
"2739"	"lovastatin"	""	"Natural product"	"yes"	""	""	""	"135652701"	"53232"	""	""	"CHEMBL503"	""	""	""	""	"[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate"	"lovastatin"	"(+)-mevinolin|6&alpha;-methylcompactin|Mevacor&reg;"	"CC[C@@H](C(=O)O[C@H]1C[C@@H](C)C=C2[C@H]1[C@@H](CC[C@@H]1C[C@@H](O)CC(=O)O1)[C@H](C=C2)C)C"	"PCZOHLXUXFIOCF-BXMDZJJMSA-N"	"InChI=1S/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1"	"yes"	""	""
"2487"	"LTB<sub>4</sub>"	""	"Metabolite"	""	""	""	""	"53801088"	"5280492"	""	""	"CHEMBL65061"	""	""	""	""	"(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid"	""	"leukotriene B<sub>4</sub>"	"CCCCC/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O"	"VNYSSYRCGWBHLG-AMOLWHMGSA-N"	"InChI=1S/C20H32O4/c1-2-3-4-5-6-9-13-18(21)14-10-7-8-11-15-19(22)16-12-17-20(23)24/h6-11,14-15,18-19,21-22H,2-5,12-13,16-17H2,1H3,(H,23,24)/b8-7+,9-6-,14-10+,15-11-/t18-,19-/m1/s1"	"yes"	""	""
"8460"	"lulizumab pegol"	""	"Antibody"	""	""	""	""	"252166670"	""	""	""	""	""	""	""	""	""	"lulizumab pegol"	"BMS-931699|BMS931699"	""	""	""	"yes"	""	""
"2897"	"lumiracoxib"	""	"Synthetic organic"	"yes"	""	""	""	"178100246"	"151166"	""	""	"CHEMBL404108"	""	""	""	""	"2-[2-[(2-chloro-6-fluorophenyl)amino]-5-methylphenyl]acetic acid"	"lumiracoxib"	"Prexige&reg;"	"OC(=O)Cc1cc(C)ccc1Nc1c(F)cccc1Cl"	"KHPKQFYUPIUARC-UHFFFAOYSA-N"	"InChI=1S/C15H13ClFNO2/c1-9-5-6-13(10(7-9)8-14(19)20)18-15-11(16)3-2-4-12(15)17/h2-7,18H,8H2,1H3,(H,19,20)"	"yes"	""	""
"14473"	"lunsekimig"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"lunsekimig"	"F027400161|SAR-443765|SAR443765"	""	""	""	"yes"	""	""
"9604"	"lusvertikimab"	""	"Antibody"	""	""	""	""	"340590234"	""	""	""	""	""	""	""	""	""	"lusvertikimab"	"Effi-7|MD-707|OSE-127|OSE127"	""	""	""	"yes"	""	""
"9297"	"lutikizumab"	""	"Antibody"	""	""	""	""	"318164816"	""	""	""	""	""	""	""	""	""	"lutikizumab"	"ABT-981|E26.13-SS-X3"	""	""	""	"yes"	""	""
"9940"	"LW106"	""	"Synthetic organic"	""	""	""	""	"363894234"	"137253428"	""	""	""	""	""	""	""	"4-[(E)-(2,3-dihydro-1H-isoindol-2-yl)(hydroxyimino)methyl]-1,2,5-oxadiazol-3-amine"	""	""	"O/N=C(\c1nonc1N)/N1Cc2c(C1)cccc2"	"QHVIXMMITPHBSL-ACCUITESSA-N"	"InChI=1S/C11H11N5O2/c12-10-9(14-18-15-10)11(13-17)16-5-7-3-1-2-4-8(7)6-16/h1-4,17H,5-6H2,(H2,12,15)/b13-11+"	"yes"	""	""
"9851"	"LX2931"	""	"Synthetic organic"	""	""	""	""	"363894145"	"136034475"	""	""	"CHEMBL1852164"	""	""	""	""	"(1R,2S,3R)-1-[(2E)-2-(1-nitrosoethylidene)-1,3-dihydroimidazol-4-yl]butane-1,2,3,4-tetrol"	""	"LX3305"	"C/C(=c/1\[nH]c(c[nH]1)[C@H]([C@@H]([C@@H](CO)O)O)O)/N=O"	"CGJLPLVZAAEKTK-LIVYHJONSA-N"	"InChI=1S/C9H15N3O5/c1-4(12-17)9-10-2-5(11-9)7(15)8(16)6(14)3-13/h2,6-8,10-11,13-16H,3H2,1H3/b9-4+/t6-,7-,8-/m1/s1"	"yes"	""	""
"5216"	"LXB<sub>4</sub>"	""	"Metabolite"	""	""	""	""	"178101901"	"5280915"	""	""	""	""	""	""	""	"(5S,6E,8Z,10E,12E,14R,15S)-5,14,15-trihydroxyicosa-6,8,10,12-tetraenoic acid"	""	"lipoxin B<sub>4</sub>"	"CCCCC[C@@H]([C@@H](/C=C/C=C/C=C\C=C\[C@H](CCCC(=O)O)O)O)O"	"UXVRTOKOJOMENI-WLPVFMORSA-N"	"InChI=1S/C20H32O5/c1-2-3-8-14-18(22)19(23)15-10-7-5-4-6-9-12-17(21)13-11-16-20(24)25/h4-7,9-10,12,15,17-19,21-23H,2-3,8,11,13-14,16H2,1H3,(H,24,25)/b6-4-,7-5+,12-9+,15-10+/t17-,18+,19-/m1/s1"	"yes"	""	""
"3351"	"LY255283"	""	"Synthetic organic"	""	""	""	""	"178100381"	"35025716"	""	""	""	""	""	""	""	"1-(2-ethyl-5-hydroxy-3-{[6-methyl-6-(1H-1,2,3,4-tetrazol-5-yl)heptyl]oxy}phenyl)ethan-1-one"	""	"CGS 23356|LY 255283|LY-255283"	"CCc1c(OCCCCCC(c2nnn[nH]2)(C)C)cc(cc1C(=O)C)O"	"VSDBVKWYFGKZPY-UHFFFAOYSA-N"	"InChI=1S/C19H28N4O3/c1-5-15-16(13(2)24)11-14(25)12-17(15)26-10-8-6-7-9-19(3,4)18-20-22-23-21-18/h11-12,25H,5-10H2,1-4H3,(H,20,21,22,23)"	"yes"	""	""
"9109"	"LY3022855"	""	"Antibody"	""	""	""	""	"315661194"	""	""	""	""	""	""	""	""	""	""	"IMC-CS4"	""	""	""	"yes"	""	""
"12211"	"LY3023703"	""	"Synthetic organic"	""	""	""	""	"472319331"	"71059525"	""	""	"CHEMBL3342693"	""	""	""	""	"2-(difluoromethyl)-5-[(2-methylpropanoylamino)methyl]-N-[5-methyl-4-[4-(trifluoromethyl)phenyl]-1H-imidazol-2-yl]pyridine-3-carboxamide"	""	"compound 9 [PMID: 25260492]"	"Cc1c(nc([nH]1)NC(=O)c1c(ncc(c1)CNC(=O)C(C)C)C(F)F)c1ccc(cc1)C(F)(F)F"	"BZYSILFNUIGABU-UHFFFAOYSA-N"	"InChI=1S/C23H22F5N5O2/c1-11(2)20(34)30-10-13-8-16(18(19(24)25)29-9-13)21(35)33-22-31-12(3)17(32-22)14-4-6-15(7-5-14)23(26,27)28/h4-9,11,19H,10H2,1-3H3,(H,30,34)(H2,31,32,33,35)"	"yes"	""	""
"13164"	"LY3509754"	""	"Synthetic organic"	""	""	""	""	"491299946"	"154642729"	""	""	""	""	""	""	""	""	""	""	"COC[C@@H](N1C[C@H](NC1=O)C(F)(F)F)C2=CC3=NC(=CN3N=C2)[C@@H](NC(=O)C4=NON=C4C)C5CCC(F)(F)CC5"	"MVWVCLAORBNXSD-UWVAXJGDSA-N"	"InChI=1S/C24H27F5N8O4/c1-12-19(35-41-34-12)21(38)33-20(13-3-5-23(25,26)6-4-13)15-9-37-18(31-15)7-14(8-30-37)16(11-40-2)36-10-17(24(27,28)29)32-22(36)39/h7-9,13,16-17,20H,3-6,10-11H2,1-2H3,(H,32,39)(H,33,38)/t16-,17+,20+/m1/s1"	"yes"	""	""
"5064"	"lymphotoxin-&alpha;"	"Human"	"Peptide"	""	""	""	""	"178101757"	""	"P01374"	"ENSG00000226979"	""	""	""	""	""	""	""	"LT&alpha;|TNF&beta;|TNFSF1"	""	""	""	"yes"	""	""
"11205"	"LYS006"	""	"Synthetic organic"	""	""	""	""	"434122265"	"118166560"	""	""	""	""	""	""	""	"(3S)-3-amino-4-[5-[4-(5-chloro-3-fluoropyridin-2-yl)oxyphenyl]tetrazol-2-yl]butanoic acid"	""	"LYS-006"	"N[C@H](Cn1nnc(n1)c1ccc(cc1)Oc1ncc(cc1F)Cl)CC(=O)O"	"ZEGMEJVULDALSH-NSHDSACASA-N"	"InChI=1S/C16H14ClFN6O3/c17-10-5-13(18)16(20-7-10)27-12-3-1-9(2-4-12)15-21-23-24(22-15)8-11(19)6-14(25)26/h1-5,7,11H,6,8,19H2,(H,25,26)/t11-/m0/s1"	"yes"	""	""
"9665"	"MAB92"	""	"Antibody"	""	""	""	""	"348353624"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9981"	"macrophage migration inhibitory factor"	"Human"	"Peptide"	""	""	""	""	"374883868"	""	"P14174"	"ENSG00000240972"	""	""	""	""	""	""	""	"L-dopachrome isomerase|MMIF"	""	""	""	"yes"	""	""
"12652"	"magrolimab"	""	"Antibody"	""	""	""	""	"483123200"	""	""	""	""	""	""	""	""	""	"magrolimab"	"Hu5F9-G4"	""	""	""	"yes"	""	""
"11096"	"MAPK13-IN-1"	""	"Synthetic organic"	""	""	""	""	"434122157"	"17941505"	""	""	"CHEMBL472620"	""	""	""	""	"1-(5-tert-butyl-2-methylpyrazol-3-yl)-3-(4-pyridin-4-yloxyphenyl)urea"	""	"compound 61 [WO2014015056A2]"	"O=C(Nc1cc(nn1C)C(C)(C)C)Nc1ccc(cc1)Oc1ccncc1"	"MHSLDASSAFCCDO-UHFFFAOYSA-N"	"InChI=1S/C20H23N5O2/c1-20(2,3)17-13-18(25(4)24-17)23-19(26)22-14-5-7-15(8-6-14)27-16-9-11-21-12-10-16/h5-13H,1-4H3,(H2,22,23,26)"	"yes"	""	""
"9654"	"mapracorat"	""	"Synthetic organic"	""	""	""	""	"340590284"	"24795088"	""	""	"CHEMBL2103876"	""	""	""	""	""	"mapracorat"	"BOL-303242-X|ZK-245186|ZK245186"	"Fc1cc2CCOc2c(c1)C(C[C@](C(F)(F)F)(CNc1cccc2c1ccc(n2)C)O)(C)C"	"VJGFOYBQOIPQFY-XMMPIXPASA-N"	"InChI=1S/C25H26F4N2O2/c1-15-7-8-18-20(5-4-6-21(18)31-15)30-14-24(32,25(27,28)29)13-23(2,3)19-12-17(26)11-16-9-10-33-22(16)19/h4-8,11-12,30,32H,9-10,13-14H2,1-3H3/t24-/m1/s1"	"yes"	""	""
"806"	"maraviroc"	""	"Synthetic organic"	"yes"	""	""	""	"135650567"	"3002977"	""	""	""	""	""	""	""	"4,4-difluoro-N-[(1S)-3-[(1R,5S)-3-(3-methyl-5-propan-2-yl-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octan-8-yl]-1-phenylpropyl]cyclohexane-1-carboxamide"	"maraviroc"	"Celsentri&reg;|Selzentry&reg;|UK 427857|UK-427,857"	"O=C(C1CCC(CC1)(F)F)N[C@H](c1ccccc1)CCN1[C@@H]2CC[C@H]1CC(C2)n1c(C)nnc1C(C)C"	"GSNHKUDZZFZSJB-HLMSNRGBSA-N"	"InChI=1S/C29H41F2N5O/c1-19(2)27-34-33-20(3)36(27)25-17-23-9-10-24(18-25)35(23)16-13-26(21-7-5-4-6-8-21)32-28(37)22-11-14-29(30,31)15-12-22/h4-8,19,22-26H,9-18H2,1-3H3,(H,32,37)/t23-,24+,25?,26-/m0/s1"	"yes"	""	""
"9891"	"marbostat-100"	""	"Synthetic organic"	""	""	""	""	"363894185"	"118884610"	""	""	""	""	""	""	""	""	""	"compound 5a [PMID: 29589441]"	"ONC(=O)c1ccc(cc1)Cn1c2CN3CC(c2c2c1cccc2)C(=O)N(C3=O)C"	"ZCAIUGLOTHAUQX-UHFFFAOYSA-N"	"InChI=1S/C22H20N4O4/c1-24-21(28)16-11-25(22(24)29)12-18-19(16)15-4-2-3-5-17(15)26(18)10-13-6-8-14(9-7-13)20(27)23-30/h2-9,16,30H,10-12H2,1H3,(H,23,27)"	"yes"	""	""
"12056"	"maresin 1"	""	"Synthetic organic"	""	""	""	""	"472319178"	"60201795"	""	""	""	""	""	""	""	"(4Z,7R,8E,10E,12Z,14S,16Z,19Z)-7,14-dihydroxydocosa-4,8,10,12,16,19-hexaenoic acid"	""	"7R,14S-dihydroxydocosa-4Z,8E,10E,12Z,16Z,19Z-hexaenoic acid|7R-Maresin 1|MaR1|Maresin-1"	"CC/C=C\C/C=C\C[C@@H](/C=C/C=C/C=C/[C@@H](C/C=C\CCC(=O)O)O)O"	"HLHYXXBCQOUTGK-LUSCUACYSA-N"	"InChI=1S/C22H32O4/c1-2-3-4-5-6-10-15-20(23)16-11-7-8-12-17-21(24)18-13-9-14-19-22(25)26/h3-4,6-13,16-17,20-21,23-24H,2,5,14-15,18-19H2,1H3,(H,25,26)/b4-3-,8-7+,10-6-,13-9-,16-11+,17-12+/t20-,21-/m0/s1"	"yes"	""	""
"12055"	"maresin 2"	""	"Synthetic organic"	""	""	""	""	"472319177"	"101894912"	""	""	""	""	""	""	""	"(4Z,7Z,9E,11E,13R,14S,16Z,19Z)-13,14-dihydroxydocosa-4,7,9,11,16,19-hexaenoic acid"	""	"13R,14S-diHDHA|13R,14S-dihydroxy-docosahexaenoic acid|MaR2|maresin-2"	"CC/C=C\C/C=C\C[C@@H]([C@@H](/C=C/C=C/C=C\C/C=C\CCC(=O)O)O)O"	"ALWYOLKNLLFCAY-GYROAIJESA-N"	"InChI=1S/C22H32O4/c1-2-3-4-5-11-14-17-20(23)21(24)18-15-12-9-7-6-8-10-13-16-19-22(25)26/h3-4,6-7,9-15,18,20-21,23-24H,2,5,8,16-17,19H2,1H3,(H,25,26)/b4-3-,7-6-,12-9+,13-10-,14-11-,18-15+/t20-,21+/m0/s1"	"yes"	""	""
"5656"	"masitinib"	""	"Synthetic organic"	""	""	""	""	"178102284"	"10074640"	""	""	"CHEMBL1908391"	""	""	""	""	"N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)-4-[(4-methylpiperazin-1-yl)methyl]benzamide"	"masitinib"	"AB-1010|AB1010|Masican&reg; (proposed trade name)"	"CN1CCN(CC1)Cc1ccc(cc1)C(=O)Nc1ccc(c(c1)Nc1scc(n1)c1cccnc1)C"	"WJEOLQLKVOPQFV-UHFFFAOYSA-N"	"InChI=1S/C28H30N6OS/c1-20-5-10-24(16-25(20)31-28-32-26(19-36-28)23-4-3-11-29-17-23)30-27(35)22-8-6-21(7-9-22)18-34-14-12-33(2)13-15-34/h3-11,16-17,19H,12-15,18H2,1-2H3,(H,30,35)(H,31,32)"	"yes"	""	""
"8580"	"mavorixafor"	""	"Synthetic organic"	"yes"	""	""	""	"252166781"	"11256587"	""	""	"CHEMBL518924"	""	""	""	""	"N-(1H-benzimidazol-2-ylmethyl)-N-[(8S)-5,6,7,8-tetrahydroquinolin-8-yl]butane-1,4-diamine"	"mavorixafor"	"AMD 070|AMD-070|AMD-11070|AMD11070|compound 2 [PMID: 20297846]|X4P-001|X4P-001-IO|X4P-001-LD|Xolremdi&reg;"	"NCCCCN([C@H]1CCCc2c1nccc2)Cc1nc2c([nH]1)cccc2"	"WVLHHLRVNDMIAR-IBGZPJMESA-N"	"InChI=1S/C21H27N5/c22-12-3-4-14-26(15-20-24-17-9-1-2-10-18(17)25-20)19-11-5-7-16-8-6-13-23-21(16)19/h1-2,6,8-10,13,19H,3-5,7,11-12,14-15,22H2,(H,24,25)/t19-/m0/s1"	"yes"	""	""
"7785"	"mavrilimumab"	""	"Antibody"	""	""	""	""	"223366117"	""	""	""	""	""	""	""	""	""	"mavrilimumab"	"CAM-3001|KPL-301"	""	""	""	"yes"	""	""
"8228"	"MCC950"	""	"Synthetic organic"	""	""	""	""	"249565908"	"9910393"	""	""	"CHEMBL3183703"	""	""	""	""	"1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[4-(2-hydroxypropan-2-yl)furan-2-yl]sulfonylurea"	""	"CP-456,773|CP-456773|CRID3|MCC-950"	"O=C(NS(=O)(=O)c1occ(c1)C(O)(C)C)Nc1c2CCCc2cc2c1CCC2"	"HUUSXLKCTQDPGL-UHFFFAOYSA-N"	"InChI=1S/C20H24N2O5S/c1-20(2,24)14-10-17(27-11-14)28(25,26)22-19(23)21-18-15-7-3-5-12(15)9-13-6-4-8-16(13)18/h9-11,24H,3-8H2,1-2H3,(H2,21,22,23)"	"yes"	""	""
"9110"	"MCS110"	""	"Antibody"	""	""	""	""	"315661195"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"4905"	"M-CSF"	"Human"	"Peptide"	""	""	""	""	"178101604"	""	"P09603"	"ENSG00000184371"	""	""	""	""	""	""	""	"CSF-1|lanimostim|macrophage-CSF"	""	""	""	"yes"	""	""
"9888"	"MDG 548"	""	"Synthetic organic"	""	""	""	""	"363894182"	"1020637"	""	""	"CHEMBL2064741"	""	""	""	""	"5-[(3-chloro-4-phenylmethoxyphenyl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione"	""	"compound 1 [PMID: 22582973]|MDG-548|MDG548"	"S=C1NC(=O)C(=Cc2ccc(c(c2)Cl)OCc2ccccc2)C(=O)N1"	"WJNBKDZARWFFKR-UHFFFAOYSA-N"	"InChI=1S/C18H13ClN2O3S/c19-14-9-12(8-13-16(22)20-18(25)21-17(13)23)6-7-15(14)24-10-11-4-2-1-3-5-11/h1-9H,10H2,(H2,20,21,22,23,25)"	"yes"	""	""
"7219"	"meclofenamic acid"	""	"Synthetic organic"	"yes"	""	""	""	"178103793"	"4037"	""	""	"CHEMBL509"	""	""	""	""	"2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid"	"meclofenamic acid"	"CL-583|INF-4668|Meclomen&reg;"	"OC(=O)c1ccccc1Nc1c(Cl)ccc(c1Cl)C"	"SBDNJUWAMKYJOX-UHFFFAOYSA-N"	"InChI=1S/C14H11Cl2NO2/c1-8-6-7-10(15)13(12(8)16)17-11-5-3-2-4-9(11)14(18)19/h2-7,17H,1H3,(H,18,19)"	"yes"	""	""
"7086"	"medrysone"	""	"Metabolite"	"yes"	""	""	""	"178103664"	"247839"	""	""	"CHEMBL1201173"	""	""	""	""	"(6S,8S,9S,10R,11S,13S,14S,17S)-17-acetyl-11-hydroxy-6,10,13-trimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one"	"medrysone"	"U-8471"	"O=C1CC[C@]2(C(=C1)[C@@H](C)C[C@@H]1[C@@H]2[C@@H](O)C[C@]2([C@H]1CC[C@@H]2C(=O)C)C)C"	"GZENKSODFLBBHQ-ILSZZQPISA-N"	"InChI=1S/C22H32O3/c1-12-9-15-17-6-5-16(13(2)23)22(17,4)11-19(25)20(15)21(3)8-7-14(24)10-18(12)21/h10,12,15-17,19-20,25H,5-9,11H2,1-4H3/t12-,15-,16+,17-,19-,20+,21-,22+/m0/s1"	"yes"	""	""
"2593"	"mefenamic acid"	""	"Synthetic organic"	"yes"	""	""	""	"53801036"	"4044"	""	""	"CHEMBL686"	""	""	""	""	"2-[(2,3-Dimethylphenyl)amino]benzoic acid"	"mefenamic acid"	"CI-473|CN-35355|INF-3355|Ponstan&reg;|Ponstel&reg;"	"OC(=O)c1ccccc1Nc1cccc(c1C)C"	"HYYBABOKPJLUIN-UHFFFAOYSA-N"	"InChI=1S/C15H15NO2/c1-10-6-5-9-13(11(10)2)16-14-8-4-3-7-12(14)15(17)18/h3-9,16H,1-2H3,(H,17,18)"	"yes"	""	""
"224"	"melatonin"	""	"Metabolite"	"yes"	""	""	""	"135651518"	"896"	""	""	"CHEMBL45"	""	""	""	""	"N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide"	""	"Circadin&reg;|MLT"	"COc1ccc2c(c1)c(CCNC(=O)C)c[nH]2"	"DRLFMBDRBRZALE-UHFFFAOYSA-N"	"InChI=1S/C13H16N2O2/c1-9(16)14-6-5-10-8-15-13-4-3-11(17-2)7-12(10)13/h3-4,7-8,15H,5-6H2,1-2H3,(H,14,16)"	"yes"	""	""
"7220"	"meloxicam"	""	"Synthetic organic"	"yes"	""	""	""	"178103794"	"54677470"	""	""	"CHEMBL599"	""	""	""	""	"4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1$l^{6},2-benzothiazine-3-carboxamide"	"meloxicam"	"Mobic&reg;|UHAC-62XX"	"Cc1cnc(s1)N=C(C1=C(O)c2ccccc2S(=O)(=O)N1C)O"	"ZRVUJXDFFKFLMG-UHFFFAOYSA-N"	"InChI=1S/C14H13N3O4S2/c1-8-7-15-14(22-8)16-13(19)11-12(18)9-5-3-4-6-10(9)23(20,21)17(11)2/h3-7,18H,1-2H3,(H,15,16,19)"	"yes"	""	""
"10172"	"mepacrine"	""	"Synthetic organic"	""	""	""	""	"381118882"	"237"	""	""	"CHEMBL7568"	""	""	""	""	"N'-(6-chloro-2-methoxyacridin-9-yl)-N,N-diethylpentane-1,4-diamine"	"mepacrine"	"Atabrine&reg;|quinacrine"	"CCN(CCCC(Nc1c2cc(OC)ccc2nc2c1ccc(c2)Cl)C)CC"	"GPKJTRJOBQGKQK-UHFFFAOYSA-N"	"InChI=1S/C23H30ClN3O/c1-5-27(6-2)13-7-8-16(3)25-23-19-11-9-17(24)14-22(19)26-21-12-10-18(28-4)15-20(21)23/h9-12,14-16H,5-8,13H2,1-4H3,(H,25,26)"	"yes"	"yes"	""
"7685"	"mepolizumab"	""	"Antibody"	"yes"	""	""	""	"223366020"	""	""	""	""	""	""	""	""	""	"mepolizumab"	"Nucala&reg;|SB-240563"	""	""	""	"yes"	""	""
"1227"	"mepyramine"	""	"Synthetic organic"	"yes"	""	""	""	"135650867"	"4992"	""	""	"CHEMBL511"	""	""	""	""	"N-[(4-methoxyphenyl)methyl]-N',N'-dimethyl-N-pyridin-2-ylethane-1,2-diamine"	"mepyramine"	"Anthisan&reg;|mepiramine|mepyramine maleate|pyrilamine|pyrilamine tannate|Pyrlex&reg;"	"COc1ccc(cc1)CN(c1ccccn1)CCN(C)C"	"YECBIJXISLIIDS-UHFFFAOYSA-N"	"InChI=1S/C17H23N3O/c1-19(2)12-13-20(17-6-4-5-11-18-17)14-15-7-9-16(21-3)10-8-15/h4-11H,12-14H2,1-3H3"	"yes"	""	""
"9841"	"merestinib"	""	"Synthetic organic"	""	""	""	""	"363894135"	"44603533"	""	""	"CHEMBL3545307"	""	""	""	""	"N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide"	"merestinib"	"LY-2801653|LY2801653"	"Fc1ccc(cc1)n1c(C)ccc(c1=O)C(=O)Nc1ccc(c(c1)F)Oc1cc2cnn(c2cc1c1c[nH]nc1)C"	"QHADVLVFMKEIIP-UHFFFAOYSA-N"	"InChI=1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19/h3-16H,1-2H3,(H,33,34)(H,36,39)"	"yes"	""	""
"13918"	"MerTK inhibitor 11"	""	"Synthetic organic"	""	""	""	""	"513757603"	"174313821"	""	""	""	""	""	""	""	"N-[4-[5-[3-[(dimethylamino)methyl]phenyl]-6-(1-methylpyrazol-4-yl)furo[2,3-d]pyrimidin-4-yl]oxyphenyl]-2-(4-fluorophenyl)-1-methyl-3-oxopyrazole-4-carboxamide"	""	""	"C12=C(N=CN=C1OC3=CC=C(C=C3)NC(=O)C=4C(=O)N(N(C4)C)C5=CC=C(C=C5)F)OC(=C2C6=CC=CC(=C6)CN(C)C)C=7C=NN(C7)C"	"WOAZQVRBSBTOAN-UHFFFAOYSA-N"	"InChI=1S/C36H31FN8O4/c1-42(2)18-22-6-5-7-23(16-22)30-31-34(38-21-39-35(31)49-32(30)24-17-40-43(3)19-24)48-28-14-10-26(11-15-28)41-33(46)29-20-44(4)45(36(29)47)27-12-8-25(37)9-13-27/h5-17,19-21H,18H2,1-4H3,(H,41,46)"	"yes"	""	""
"2700"	"mesalazine"	""	"Synthetic organic"	"yes"	""	""	""	"135649824"	"4075"	""	""	"CHEMBL704"	""	""	""	""	"5-Amino-2-hydroxybenzoic acid"	"mesalazine"	"5-aminosalicylic acid|5-ASA|mesalamine (USAN)|Pentasa&reg;"	"Nc1ccc(c(c1)C(=O)O)O"	"KBOPZPXVLCULAV-UHFFFAOYSA-N"	"InChI=1S/C7H7NO3/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3,9H,8H2,(H,10,11)"	"yes"	""	""
"1614"	"[Met]enkephalin"	"Human, Mouse, Rat"	"Peptide"	""	""	""	""	"135651808"	"443363"	"P04094|P22005|P01210"	"ENSRNOG00000008943|ENSMUSG00000045573|ENSG00000181195"	"CHEMBL13786"	""	""	""	""	"(2S)-2-[[(2S)-2-[[2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoic acid"	"metenkefalin"	"1-5 Adrenorphin|[Met]-enkephalin|IRT-101|methionine enkephalin|np2 enkephalin|opioid growth factor (OGF)"	"CSCC[C@@H](C(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(cc1)O)N"	"YFGBQHOOROIVKG-FKBYEOEOSA-N"	"InChI=1S/C27H35N5O7S/c1-40-12-11-21(27(38)39)32-26(37)22(14-17-5-3-2-4-6-17)31-24(35)16-29-23(34)15-30-25(36)20(28)13-18-7-9-19(33)10-8-18/h2-10,20-22,33H,11-16,28H2,1H3,(H,29,34)(H,30,36)(H,31,35)(H,32,37)(H,38,39)/t20-,21-,22-/m0/s1"	"yes"	""	""
"4779"	"metformin"	""	"Synthetic organic"	"yes"	""	""	""	"178101481"	"4091"	""	""	"CHEMBL1431"	""	""	""	""	"1-[(diaminomethylidene)amino]-N,N-dimethylmethanimidamide"	"metformin"	"Glucophage&reg;|LA-6023"	"CN(C(=N)N=C(N)N)C"	"XZWYZXLIPXDOLR-UHFFFAOYSA-N"	"InChI=1S/C4H11N5/c1-9(2)4(7)8-3(5)6/h1-2H3,(H5,5,6,7,8)"	"yes"	""	""
"7438"	"methacholine"	""	"Synthetic organic"	"yes"	""	""	""	"178104010"	"1993"	""	""	"CHEMBL978"	""	""	""	""	"2-acetyloxypropyl-trimethylazanium"	"methacholine chloride"	"methacholine bromide|Provocholine&reg;"	"CC(C[N+](C)(C)C)OC(=O)C"	"NZWOPGCLSHLLPA-UHFFFAOYSA-N"	"InChI=1S/C8H18NO2/c1-7(11-8(2)10)6-9(3,4)5/h7H,6H2,1-5H3/q+1"	"yes"	""	""
"6649"	"methimazole"	""	"Synthetic organic"	"yes"	""	""	""	"178103262"	"1349907"	""	""	"CHEMBL1515"	""	""	""	""	"1-methyl-3H-imidazole-2-thione"	""	"Tapazole&reg;|Thiamazole&reg;"	"Cn1ccnc1S"	"PMRYVIKBURPHAH-UHFFFAOYSA-N"	"InChI=1S/C4H6N2S/c1-6-3-2-5-4(6)7/h2-3H,1H3,(H,5,7)"	"yes"	""	""
"4815"	"methotrexate"	""	"Synthetic organic"	"yes"	""	""	""	"178101517"	"126941"	""	""	"CHEMBL34259"	""	""	""	""	"(2S)-2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}phenyl)formamido]pentanedioic acid"	"methotrexate"	"Abitrexate&reg;|amethopterin|Nordimet&reg;|Rasuvo&reg;"	"OC(=O)CC[C@@H](C(=O)O)NC(=O)c1ccc(cc1)N(Cc1cnc2c(n1)c(N)nc(n2)N)C"	"FBOZXECLQNJBKD-ZDUSSCGKSA-N"	"InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27)/t13-/m0/s1"	"yes"	""	""
"7088"	"methylprednisolone"	""	"Metabolite"	"yes"	""	""	""	"178103666"	"6741"	""	""	"CHEMBL650"	""	""	""	""	"(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one"	"methylprednisolone"	"Medrol&reg;|U-67590A"	"OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2C[C@@H](C2=CC(=O)C=C[C@]12C)C"	"VHRSUDSXCMQTMA-PJHHCJLFSA-N"	"InChI=1S/C22H30O5/c1-12-8-14-15-5-7-22(27,18(26)11-23)21(15,3)10-17(25)19(14)20(2)6-4-13(24)9-16(12)20/h4,6,9,12,14-15,17,19,23,25,27H,5,7-8,10-11H2,1-3H3/t12-,14-,15-,17-,19+,20-,21-,22-/m0/s1"	"yes"	""	""
"10609"	"mezagitamab"	""	"Antibody"	""	""	""	""	"404859056"	""	""	""	""	""	""	""	""	""	"mezagitamab"	"TAK-079|TAK079"	""	""	""	"yes"	""	""
"12718"	"mezigdomide"	""	"Synthetic organic"	""	""	""	""	"483123266"	"137379043"	""	""	"CHEMBL4648616"	""	""	""	""	"4-[4-[[4-[[2-[(3S)-2,6-dioxopiperidin-3-yl]-1-oxo-3H-isoindol-4-yl]oxymethyl]phenyl]methyl]piperazin-1-yl]-3-fluorobenzonitrile"	"mezigdomide"	"BMS-986348|BMS986348|CC-92480|CC92480|compound 4 [PMID: 32130004]"	"O=C1NC([C@H](CC1)N2CC=3C(OCC4=CC=C(CN5CCN(C6=CC=C(C#N)C=C6F)CC5)C=C4)=CC=CC3C2=O)=O"	"YTINZZFBHWSAGL-NDEPHWFRSA-N"	"InChI=1S/C32H30FN5O4/c33-26-16-23(17-34)8-9-27(26)37-14-12-36(13-15-37)18-21-4-6-22(7-5-21)20-42-29-3-1-2-24-25(29)19-38(32(24)41)28-10-11-30(39)35-31(28)40/h1-9,16,28H,10-15,18-20H2,(H,35,39,40)/t28-/m0/s1"	"yes"	""	""
"9890"	"MIDD0301"	""	"Synthetic organic"	""	""	""	""	"363894184"	"133081966"	""	""	""	""	""	""	""	""	""	""	"Brc1ccc2c(c1)C(=N[C@@H](c1n2cnc1C(=O)O)C)c1ccccc1F"	"OSBXEAZWQGBYFU-SNVBAGLBSA-N"	"InChI=1S/C19H13BrFN3O2/c1-10-18-17(19(25)26)22-9-24(18)15-7-6-11(20)8-13(15)16(23-10)12-4-2-3-5-14(12)21/h2-10H,1H3,(H,25,26)/t10-/m1/s1"	"yes"	""	""
"5702"	"midostaurin"	""	"Synthetic organic"	"yes"	""	""	""	"178102329"	"9829523"	""	""	"CHEMBL608533"	""	""	""	""	"N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8,10,12,14(28),15(19),20(27),21,23,25-nonaen-4-yl]-N-methylbenzamide"	"midostaurin"	"CGP 41231|CGP 41251|N-benzoylstaurosporine|PKC412|Rydapt&reg;"	"CO[C@@H]1[C@@H](C[C@H]2O[C@]1(C)n1c3ccccc3c3c1c1n2c2ccccc2c1c1c3CNC1=O)N(C(=O)c1ccccc1)C"	"BMGQWWVMWDBQGC-IIFHNQTCSA-N"	"InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1"	"yes"	""	""
"2805"	"mifepristone"	""	"Synthetic organic"	"yes"	""	""	""	"135650608"	"55245"	""	""	"CHEMBL1276308"	""	""	""	""	"(8S,11R,13S,14S,17S)-11-(4-dimethylaminophenyl)-17-hydroxy-13-methyl-17-prop-1-ynyl-1,2,6,7,8,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-3-one"	"mifepristone"	"Mifeprex&reg;|RU-486|RU486"	"CC#C[C@]1(O)CC[C@@H]2[C@]1(C)C[C@H](c1ccc(cc1)N(C)C)C1=C3CCC(=O)C=C3CC[C@@H]21"	"VKHAHZOOUSRJNA-GCNJZUOMSA-N"	"InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1"	"yes"	""	""
"9986"	"MIF inhibitor 3bb"	""	"Synthetic organic"	""	""	""	""	"374883873"	"91667576"	""	""	"CHEMBL3917143"	""	""	""	""	"3-[2-[1-(3-fluoro-4-hydroxyphenyl)triazol-4-yl]quinolin-5-yl]oxybenzoic acid"	""	""	"OC(=O)c1cccc(c1)Oc1cccc2c1ccc(n2)c1nnn(c1)c1ccc(c(c1)F)O"	"RXHQCISHMPQZDT-UHFFFAOYSA-N"	"InChI=1S/C24H15FN4O4/c25-18-12-15(7-10-22(18)30)29-13-21(27-28-29)20-9-8-17-19(26-20)5-2-6-23(17)33-16-4-1-3-14(11-16)24(31)32/h1-13,30H,(H,31,32)"	"yes"	""	""
"10463"	"milategrast"	""	"Synthetic organic"	""	""	""	""	"385612223"	"11302685"	""	""	""	""	""	""	""	"1-(cyclopropylmethyl)-4-[2-(3,3,5,5-tetramethylcyclohexyl)phenyl]piperazine"	"milategrast"	"example 9 [US20050261291A1]"	"CC1(C)CC(CC(C1)(C)C)c1ccccc1N1CCN(CC1)CC1CC1"	"PGWIKFFLIJECAM-UHFFFAOYSA-N"	"InChI=1S/C24H38N2/c1-23(2)15-20(16-24(3,4)18-23)21-7-5-6-8-22(21)26-13-11-25(12-14-26)17-19-9-10-19/h5-8,19-20H,9-18H2,1-4H3"	"yes"	""	""
"8267"	"milatuzumab"	""	"Antibody"	""	""	""	""	"252166479"	""	""	""	""	""	""	""	""	""	"milatuzumab"	"hLL1|IMMU-115"	""	""	""	"yes"	""	""
"11355"	"miltefosine"	""	"Synthetic organic"	"yes"	""	""	""	"440816724"	"3599"	""	""	"CHEMBL125"	""	""	""	""	"hexadecyl 2-(trimethylazaniumyl)ethyl phosphate"	"miltefosine"	"D-18506|D18506|Impavido&reg;|Miltex&reg;|n-hexadecylphosphorylcholine"	"CCCCCCCCCCCCCCCCOP(=O)(OCC[N+](C)(C)C)[O-]"	"PQLXHQMOHUQAKB-UHFFFAOYSA-N"	"InChI=1S/C21H46NO4P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20-25-27(23,24)26-21-19-22(2,3)4/h5-21H2,1-4H3"	"yes"	""	""
"9846"	"mirikizumab"	""	"Antibody"	"yes"	""	""	""	"363894140"	""	""	""	""	""	""	""	""	""	"mirikizumab"	"Antibody I [US9023358]|LY-3074828|LY3074828|mirikizumab-mrkz|Omvoh&reg;"	""	""	""	"yes"	""	""
"9600"	"mivavotinib"	""	"Synthetic organic"	""	""	""	""	"340590230"	"53252276"	""	""	""	""	""	""	""	"6-[[(1R,2S)-2-aminocyclohexyl]amino]-7-fluoro-4-(1-methylpyrazol-4-yl)-1,2-dihydropyrrolo[3,4-c]pyridin-3-one"	"mivavotinib"	"compound 3b [PMID: 27839918]|TAK-659|TAK659"	"N[C@H]1CCCC[C@H]1Nc1nc(c2cnn(c2)C)c2c(c1F)CNC2=O"	"MJHOMTRKVMKCNE-NWDGAFQWSA-N"	"InChI=1S/C17H21FN6O/c1-24-8-9(6-21-24)15-13-10(7-20-17(13)25)14(18)16(23-15)22-12-5-3-2-4-11(12)19/h6,8,11-12H,2-5,7,19H2,1H3,(H,20,25)(H,22,23)/t11-,12+/m0/s1"	"yes"	""	""
"10102"	"mizolastine"	""	"Synthetic organic"	"yes"	""	""	""	"381118812"	"65906"	""	""	"CHEMBL94454"	""	""	""	""	""	"mizolastine"	"Mizollen&reg;|MKC-431|MKC431|SL 85.0324|SL-850324|SL850324"	"Fc1ccc(cc1)Cn1c(nc2c1cccc2)N1CCC(CC1)N(c1nccc(=O)[nH]1)C"	"PVLJETXTTWAYEW-UHFFFAOYSA-N"	"InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)"	"yes"	""	""
"9852"	"MK-0359"	""	"Synthetic organic"	""	""	""	""	"363894146"	"9853498"	""	""	"CHEMBL372575"	""	""	""	""	"3-methyl-5-[(E)-1-(4-methylsulfonylphenyl)-2-[3-[6-(2-methylsulfonylpropan-2-yl)quinolin-8-yl]phenyl]ethenyl]-1,2,4-oxadiazole"	""	"L-454,560|L-454560|MK0359"	"Cc1noc(n1)/C(=C/c1cccc(c1)c1cc(cc2c1nccc2)C(S(=O)(=O)C)(C)C)/c1ccc(cc1)S(=O)(=O)C"	"YYGZHVJDHMMABU-OGLMXYFKSA-N"	"InChI=1S/C31H29N3O5S2/c1-20-33-30(39-34-20)28(22-11-13-26(14-12-22)40(4,35)36)17-21-8-6-9-23(16-21)27-19-25(31(2,3)41(5,37)38)18-24-10-7-15-32-29(24)27/h6-19H,1-5H3/b28-17+"	"yes"	""	""
"9048"	"MK-0812"	""	"Synthetic organic"	""	""	""	""	"315661133"	"11180808"	""	""	"CHEMBL3305901"	""	""	""	""	"[(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[3-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone"	""	"MK0812"	"CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1CCc2c(C1)cc(cn2)C(F)(F)F"	"MTMDXAIUENDNDL-RJSMDTJLSA-N"	"InChI=1S/C24H34F3N3O3/c1-15(2)23(7-4-18(11-23)29-20-6-9-33-14-21(20)32-3)22(31)30-8-5-19-16(13-30)10-17(12-28-19)24(25,26)27/h10,12,15,18,20-21,29H,4-9,11,13-14H2,1-3H3/t18-,20+,21-,23+/m1/s1"	"yes"	""	""
"9853"	"MK-0873"	""	"Synthetic organic"	""	""	""	""	"363894147"	"9919680"	""	""	"CHEMBL485629"	""	""	""	""	"N-cyclopropyl-1-[3-[2-(1-oxidopyridin-1-ium-3-yl)ethynyl]phenyl]-4-oxo-1,8-naphthyridine-3-carboxamide"	""	"compound 20 [PMID: 18835163]|MK0873"	"[O-][n+]1cccc(c1)C#Cc1cccc(c1)n1cc(C(=O)NC2CC2)c(=O)c2c1nccc2"	"JJWKQXNHYDJXKF-UHFFFAOYSA-N"	"InChI=1S/C25H18N4O3/c30-23-21-7-2-12-26-24(21)29(16-22(23)25(31)27-19-10-11-19)20-6-1-4-17(14-20)8-9-18-5-3-13-28(32)15-18/h1-7,12-16,19H,10-11H2,(H,27,31)"	"yes"	""	""
"14311"	"MK-2118"	""	"Synthetic organic"	""	""	""	""	"523352103"	"134391948"	""	""	"CHEMBL4570444"	""	""	""	""	"(2S)-4-(5,6-dimethoxy-1-benzothiophen-2-yl)-2-methyl-4-oxobutanoic acid"	""	"example 11 [US10730849B2]|MK2118"	"C[C@@H](CC(=O)C1=CC2=CC(=C(C=C2S1)OC)OC)C(=O)O"	"WBHPMBQELUEIIV-QMMMGPOBSA-N"	"InChI=1S/C15H16O5S/c1-8(15(17)18)4-10(16)14-6-9-5-11(19-2)12(20-3)7-13(9)21-14/h5-8H,4H2,1-3H3,(H,17,18)/t8-/m0/s1"	"yes"	""	""
"11395"	"MK-7110"	""	"Peptide"	""	""	""	""	"440816764"	""	""	""	""	""	""	""	""	""	""	"CD24-Fc|CD24Fc"	""	""	""	"yes"	""	""
"2655"	"MK-886"	""	"Synthetic organic"	""	""	""	""	"135650618"	"3651377"	""	""	"CHEMBL29097"	""	""	""	""	"3-[3-tert-butylsulfanyl-1-[(4-chlorophenyl)methyl]-5-propan-2-ylindol-2-yl]-2,2-dimethylpropanoic acid"	""	"L 663536|MK886"	"Clc1ccc(cc1)Cn1c2ccc(cc2c(c1CC(C(=O)O)(C)C)SC(C)(C)C)C(C)C"	"QAOAOVKBIIKRNL-UHFFFAOYSA-N"	"InChI=1S/C27H34ClNO2S/c1-17(2)19-10-13-22-21(14-19)24(32-26(3,4)5)23(15-27(6,7)25(30)31)29(22)16-18-8-11-20(28)12-9-18/h8-14,17H,15-16H2,1-7H3,(H,30,31)"	"yes"	""	""
"8887"	"ML130"	""	"Synthetic organic"	""	""	""	""	"310264668"	"1088438"	""	""	"CHEMBL1412853"	""	""	""	""	"1-(4-methylphenyl)sulfonylbenzimidazol-2-amine"	""	"compound 1c [PMID: 22003428]|ML-130|Noditinib-1"	"Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2c1cccc2"	"SRFABRWQVPCPRG-UHFFFAOYSA-N"	"InChI=1S/C14H13N3O2S/c1-10-6-8-11(9-7-10)20(18,19)17-13-5-3-2-4-12(13)16-14(17)15/h2-9H,1H3,(H2,15,16)"	"yes"	""	""
"10301"	"ML2-SA1"	""	"Synthetic organic"	""	""	""	""	"381744982"	"137553170"	""	""	""	""	""	""	""	""	""	"EVP-22|EVP22|ML2 SA1|ML2SA1"	"Clc1cccc(c1C1=NOC2C1C1CCC2C1)Cl"	"NBXVMFMMTKYFQP-UHFFFAOYSA-N"	"InChI=1S/C14H13Cl2NO/c15-9-2-1-3-10(16)12(9)13-11-7-4-5-8(6-7)14(11)18-17-13/h1-3,7-8,11,14H,4-6H2"	"yes"	""	""
"9584"	"ML324"	""	"Synthetic organic"	""	""	""	""	"340590215"	"44143209"	""	""	"CHEMBL1398529"	""	""	""	""	"N-[3-(dimethylamino)propyl]-4-(8-hydroxyquinolin-6-yl)benzamide"	""	"ML-324|MMV1580488"	"CN(CCCNC(=O)c1ccc(cc1)c1cc(O)c2c(c1)cccn2)C"	"QDBVSOZTVKXUES-UHFFFAOYSA-N"	"InChI=1S/C21H23N3O2/c1-24(2)12-4-11-23-21(26)16-8-6-15(7-9-16)18-13-17-5-3-10-22-20(17)19(25)14-18/h3,5-10,13-14,25H,4,11-12H2,1-2H3,(H,23,26)"	"yes"	"yes"	""
"5694"	"MLN-120B"	""	"Synthetic organic"	""	""	""	""	"178102321"	"9929127"	""	""	"CHEMBL608154"	""	""	""	""	"N-{6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl}-2-methylpyridine-3-carboxamide"	""	"ML120B|MLN120B"	"COc1c(Cl)cc2c(c1NC(=O)c1cccnc1C)[nH]c1c2ccnc1"	"ZNOLRTPMNMPLHY-UHFFFAOYSA-N"	"InChI=1S/C19H15ClN4O2/c1-10-11(4-3-6-22-10)19(25)24-17-16-13(8-14(20)18(17)26-2)12-5-7-21-9-15(12)23-16/h3-9,23H,1-2H3,(H,24,25)"	"yes"	""	""
"9944"	"MM-433593"	""	"Synthetic organic"	""	""	""	""	"363894237"	"25143721"	""	""	""	""	""	""	""	"2-[1-[(4-chlorophenyl)methyl]-2,5-dimethylindol-3-yl]-N-(2-methoxypyridin-4-yl)-2-oxoacetamide"	""	"MM433593"	"COc1nccc(c1)NC(=O)C(=O)c1c2cc(C)ccc2n(c1C)Cc1ccc(cc1)Cl"	"RIKZRSJVZWKHNX-UHFFFAOYSA-N"	"InChI=1S/C25H22ClN3O3/c1-15-4-9-21-20(12-15)23(16(2)29(21)14-17-5-7-18(26)8-6-17)24(30)25(31)28-19-10-11-27-22(13-19)32-3/h4-13H,14H2,1-3H3,(H,27,28,31)"	"yes"	""	""
"6240"	"MMK-1"	""	"Peptide"	""	""	""	""	"178102861"	"25074458"	""	""	""	""	""	""	""	""	""	"MMK 1"	"CSCC[C@@H](C(=O)O)NC(=O)[C@H](C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]([C@H](CC)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)N)CCC(=O)O)CO)Cc1ccccc1)CCCN=C(N)N)CO)CC(C)C)CC(C)C)Cc1ccccc1)CCCN=C(N)N"	"PWBQRCXCXXGUGY-AJOXZCOLSA-N"	"InChI=1S/C75H123N19O18S/c1-12-44(10)60(94-70(108)57(39-96)92-63(101)50(27-28-58(97)98)83-61(99)47(76)33-40(2)3)72(110)90-55(37-46-23-17-14-18-24-46)68(106)84-48(25-19-30-81-74(77)78)62(100)91-56(38-95)69(107)88-53(35-42(6)7)65(103)87-52(34-41(4)5)66(104)89-54(36-45-21-15-13-16-22-45)67(105)85-49(26-20-31-82-75(79)80)64(102)93-59(43(8)9)71(109)86-51(73(111)112)29-32-113-11/h13-18,21-24,40-44,47-57,59-60,95-96H,12,19-20,25-39,76H2,1-11H3,(H,83,99)(H,84,106)(H,85,105)(H,86,109)(H,87,103)(H,88,107)(H,89,104)(H,90,110)(H,91,100)(H,92,101)(H,93,102)(H,94,108)(H,97,98)(H,111,112)(H4,77,78,81)(H4,79,80,82)/t44-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-,57-,59-,60-/m0/s1"	"yes"	""	""
"9727"	"mocravimod"	""	"Synthetic organic"	""	""	""	""	"354702203"	"11155874"	""	""	"CHEMBL2137148"	""	""	""	""	"2-Amino-2-(2-(2-chloro-4-(3-benzyloxyphenylthio)phenyl)ethyl)-1,3-propanediol"	"mocravimod"	"compound 2 [PMID: 23124563]|KRP-203|KRP203"	"OCC(CCc1ccc(cc1Cl)Sc1cccc(c1)OCc1ccccc1)(CO)N"	"IINUNQPYJGJCJI-UHFFFAOYSA-N"	"InChI=1S/C24H26ClNO3S/c25-23-14-22(10-9-19(23)11-12-24(26,16-27)17-28)30-21-8-4-7-20(13-21)29-15-18-5-2-1-3-6-18/h1-10,13-14,27-28H,11-12,15-17,26H2"	"yes"	""	""
"2923"	"mocravimod-phosphate"	""	"Synthetic organic"	""	""	""	""	"135650459"	"56947075"	""	""	""	""	""	""	""	"[2-amino-2-(2-{2-chloro-4-[(3-phenoxyphenyl)sulfanyl]phenyl}ethyl)-3-hydroxypropoxy]phosphonic acid"	""	"KRP 203-phosphate|KRP203-phosphate"	"OCC(COP(=O)(O)O)(CCc1ccc(cc1Cl)Sc1cccc(c1)Oc1ccccc1)N"	"BZVUYJGCYLMFGX-UHFFFAOYSA-N"	"InChI=1S/C23H25ClNO6PS/c24-22-14-21(10-9-17(22)11-12-23(25,15-26)16-30-32(27,28)29)33-20-8-4-7-19(13-20)31-18-5-2-1-3-6-18/h1-10,13-14,26H,11-12,15-16,25H2,(H2,27,28,29)"	"yes"	""	""
"9754"	"mofegiline"	""	"Synthetic organic"	""	""	""	""	"354702227"	"6437850"	""	""	"CHEMBL489079"	""	""	""	""	"(2E)-2-(fluoromethylidene)-4-(4-fluorophenyl)butan-1-amine"	"mofegiline"	"MDL 72974|MDL-72,974|MDL-72974A"	"NC/C(=C/F)/CCc1ccc(cc1)F"	"VXLBSYHAEKDUSU-JXMROGBWSA-N"	"InChI=1S/C11H13F2N/c12-7-10(8-14)2-1-9-3-5-11(13)6-4-9/h3-7H,1-2,8,14H2/b10-7+"	"yes"	""	""
"6477"	"mogamulizumab"	""	"Antibody"	"yes"	""	""	""	"178103091"	""	""	""	""	""	""	""	""	""	"mogamulizumab"	"KW-0761|mogamulizumab-kpkc|Poteligeo&reg;"	""	""	""	"yes"	""	""
"7033"	"molibresib"	""	"Synthetic organic"	""	""	""	""	"178103612"	"46943432"	""	""	"CHEMBL1232461"	""	""	""	""	"2-[(4S)-6-(4-chlorophenyl)-8-methoxy-1-methyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]-N-ethylacetamide"	"molibresib"	"CS-0717|GSK 525762A|GSK-525762|GSK525762|I-BET-762|I-BET762"	"CCNC(=O)C[C@@H]1N=C(c2ccc(cc2)Cl)c2c(n3c1nnc3C)ccc(c2)OC"	"AAAQFGUYHFJNHI-SFHVURJKSA-N"	"InChI=1S/C22H22ClN5O2/c1-4-24-20(29)12-18-22-27-26-13(2)28(22)19-10-9-16(30-3)11-17(19)21(25-18)14-5-7-15(23)8-6-14/h5-11,18H,4,12H2,1-3H3,(H,24,29)/t18-/m0/s1"	"yes"	""	""
"9029"	"mometasone"	""	"Synthetic organic"	"yes"	""	""	""	"315661114"	"441335"	""	""	"CHEMBL1201404"	""	""	""	""	"(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one"	"mometasone"	"Elocon&reg; (topical)|Nasonex&reg;"	"ClCC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)Cl"	"QLIIKPVHVRXHRI-CXSFZGCWSA-N"	"InChI=1S/C22H28Cl2O4/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,24)17(26)10-20(16,3)22(12,28)18(27)11-23/h6-7,9,12,15-17,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1"	"yes"	""	""
"8323"	"monalizumab"	""	"Antibody"	""	""	""	""	"252166535"	""	""	""	""	""	""	""	""	""	"monalizumab"	"humZ270|IPH-2201|NN8765-3658"	""	""	""	"yes"	""	""
"8277"	"mongersen"	""	"Nucleic acid"	""	""	""	""	"252166489"	"121490254"	""	""	"CHEMBL3707383"	""	""	""	""	"2'-deoxy-P-thio-guanylyl-(3'->5')-P-thio-thymidylyl-(3'->5')-2'-deoxy-5-methyl-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-guanylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-P-thio-thymidylyl-(3'->5')-P-thio-thymidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-P-thio-thymidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-5-methyl-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-guanylyl-(3'->5')-2'-deoxy-P-thio-cytidylyl-(3'->5')-2'-deoxy-P-thio-adenylyl-(3'->5')-2'-deoxy-P-thio-guanylyl-(3'->5')-2'-deoxy-cytidine"	"mongersen"	"DNA, d(P-thio)(G-T-m5C-G-C-C-C-C-T-T-C-T-C-C-C-m5C-G-C-A-G-C)|GED-0301|GED0301"	"CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=S)(O)O[C@H]3C[C@@H](O[C@@H]3CO)N4C=NC5=C4N=C(NC5=O)N)OP(=S)(O)OC[C@@H]6[C@H](C[C@@H](O6)N7C=C(C(=NC7=O)N)C)OP(=S)(O)OC[C@@H]8[C@H](C[C@@H](O8)N9C=NC%10=C9N=C(NC%10=O)N)OP(=S)(O)OC[C@@H]%11[C@H](C[C@@H](O%11)N%12C=CC(=NC%12=O)N)OP(=S)(O)OC[C@@H]%13[C@H](C[C@@H](O%13)N%14C=CC(=NC%14=O)N)OP(=S)(O)OC[C@@H]%15[C@H](C[C@@H](O%15)N%16C=CC(=NC%16=O)N)OP(=S)(O)OC[C@@H]%17[C@H](C[C@@H](O%17)N%18C=CC(=NC%18=O)N)OP(=S)(O)OC[C@@H]%19[C@H](C[C@@H](O%19)N%20C=C(C(=O)NC%20=O)C)OP(=S)(O)OC[C@@H]%21[C@H](C[C@@H](O%21)N%22C=C(C(=O)NC%22=O)C)OP(=S)(O)OC[C@@H]%23[C@H](C[C@@H](O%23)N%24C=CC(=NC%24=O)N)OP(=S)(O)OC[C@@H]%25[C@H](C[C@@H](O%25)N%26C=C(C(=O)NC%26=O)C)OP(=S)(O)OC[C@@H]%27[C@H](C[C@@H](O%27)N%28C=CC(=NC%28=O)N)OP(=S)(O)OC[C@@H]%29[C@H](C[C@@H](O%29)N%30C=CC(=NC%30=O)N)OP(=S)(O)OC[C@@H]%31[C@H](C[C@@H](O%31)N%32C=CC(=NC%32=O)N)OP(=S)(O)OC[C@@H]%33[C@H](C[C@@H](O%33)N%34C=C(C(=NC%34=O)N)C)OP(=S)(O)OC[C@@H]%35[C@H](C[C@@H](O%35)N%36C=NC%37=C%36N=C(NC%37=O)N)OP(=S)(O)OC[C@@H]%38[C@H](C[C@@H](O%38)N%39C=CC(=NC%39=O)N)OP(=S)(O)OC[C@@H]%40[C@H](C[C@@H](O%40)N%41C=NC%42=C(N=CN=C%42%41)N)OP(=S)(O)OC[C@@H]%43[C@H](C[C@@H](O%43)N%44C=NC%45=C%44N=C(NC%45=O)N)OP(=S)(O)OC[C@@H]%46[C@H](C[C@@H](O%46)N%47C=CC(=NC%47=O)N)O"	"ABASMUXUCSQFKC-PKEKLUKKSA-N"	"InChI=1S/C200H261N69O107P20S20/c1-81-48-259(195(290)235-165(81)211)149-38-98(367-392(311,412)333-73-127-107(47-159(355-127)269-80-224-164-172(269)240-184(217)244-180(164)279)376-395(314,415)326-64-118-97(37-148(346-118)258-26-16-138(210)234-194(258)289)366-387(306,407)332-71-125-104(44-155(353-125)265-76-220-160-167(213)218-75-219-168(160)265)374-396(315,416)335-72-126-105(45-157(354-126)267-78-222-162-170(267)238-182(215)242-178(162)277)373-377(296,397)316-55-109-87(271)27-139(337-109)249-17-7-129(201)225-185(249)280)119(347-149)66-327-384(303,404)363-94-34-145(255-23-13-135(207)231-191(255)286)341-113(94)59-321-380(299,400)359-91-31-142(252-20-10-132(204)228-188(252)283)339-111(91)57-319-382(301,402)361-92-32-143(253-21-11-133(205)229-189(253)284)343-115(92)61-323-388(307,408)369-101-41-152(262-51-84(4)174(273)246-198(262)293)350-122(101)68-328-386(305,406)365-96-36-147(257-25-15-137(209)233-193(257)288)344-116(96)62-324-389(308,409)370-102-42-153(263-52-85(5)175(274)247-199(263)294)352-124(102)70-331-391(310,411)372-103-43-154(264-53-86(6)176(275)248-200(264)295)351-123(103)69-329-385(304,405)364-95-35-146(256-24-14-136(208)232-192(256)287)342-114(95)60-322-381(300,401)360-90-30-141(251-19-9-131(203)227-187(251)282)338-110(90)56-318-379(298,399)358-89-29-140(250-18-8-130(202)226-186(250)281)340-112(89)58-320-383(302,403)362-93-33-144(254-22-12-134(206)230-190(254)285)345-117(93)63-325-394(313,414)375-106-46-158(268-79-223-163-171(268)239-183(216)243-179(163)278)356-128(106)74-334-393(312,413)368-99-39-150(260-49-82(2)166(212)236-196(260)291)348-120(99)67-330-390(309,410)371-100-40-151(261-50-83(3)173(272)245-197(261)292)349-121(100)65-317-378(297,398)357-88-28-156(336-108(88)54-270)266-77-221-161-169(266)237-181(214)241-177(161)276/h7-26,48-53,75-80,87-128,139-159,270-271H,27-47,54-74H2,1-6H3,(H,296,397)(H,297,398)(H,298,399)(H,299,400)(H,300,401)(H,301,402)(H,302,403)(H,303,404)(H,304,405)(H,305,406)(H,306,407)(H,307,408)(H,308,409)(H,309,410)(H,310,411)(H,311,412)(H,312,413)(H,313,414)(H,314,415)(H,315,416)(H2,201,225,280)(H2,202,226,281)(H2,203,227,282)(H2,204,228,283)(H2,205,229,284)(H2,206,230,285)(H2,207,231,286)(H2,208,232,287)(H2,209,233,288)(H2,210,234,289)(H2,211,235,290)(H2,212,236,291)(H2,213,218,219)(H,245,272,292)(H,246,273,293)(H,247,274,294)(H,248,275,295)(H3,214,237,241,276)(H3,215,238,242,277)(H3,216,239,243,278)(H3,217,240,244,279)/t87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108+,109+,110+,111+,112+,113+,114+,115+,116+,117+,118+,119+,120+,121+,122+,123+,124+,125+,126+,127+,128+,139+,140+,141+,142+,143+,144+,145+,146+,147+,148+,149+,150+,151+,152+,153+,154+,155+,156+,157+,158+,159+,377?,378?,379?,380?,381?,382?,383?,384?,385?,386?,387?,388?,389?,390?,391?,392?,393?,394?,395?,396?/m0/s1"	"yes"	""	""
"5786"	"monomethyl fumarate"	""	"Synthetic organic"	""	""	""	""	"178102411"	"5369209"	""	""	"CHEMBL589586"	""	""	""	""	"4-methoxy-4-oxobut-2-enoic acid"	"monomethyl fumarate"	"methyl hydrogen fumarate"	"COC(=O)/C=C/C(=O)O"	"NKHAVTQWNUWKEO-NSCUHMNNSA-N"	"InChI=1S/C5H6O4/c1-9-5(8)3-2-4(6)7/h2-3H,1H3,(H,6,7)/b3-2+"	"yes"	""	""
"3340"	"montelukast"	""	"Synthetic organic"	"yes"	""	""	""	"178100370"	"5281040"	""	""	"CHEMBL787"	""	""	""	""	"2-[1-({[(1R)-1-{3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl}-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanyl}methyl)cyclopropyl]acetic acid"	"montelukast"	"Singulair&reg;"	"OC(=O)CC1(CS[C@@H](c2cccc(c2)/C=C/c2ccc3c(n2)cc(cc3)Cl)CCc2ccccc2C(O)(C)C)CC1"	"UCHDWCPVSPXUMX-TZIWLTJVSA-N"	"InChI=1S/C35H36ClNO3S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-/m1/s1"	"yes"	""	""
"9771"	"mosedipimod"	""	"Synthetic organic"	""	""	""	""	"354702244"	"9960925"	""	""	""	""	""	""	""	"(1-acetyloxy-3-hexadecanoyloxypropan-2-yl) (9Z,12Z)-octadeca-9,12-dienoate"	"mosedipimod"	"EC-18|Plag, (+/-)"	"CCCCCCCCCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COC(=O)C"	"GAKUNXBDVGLOFS-UHFFFAOYSA-N"	"InChI=1S/C39H70O6/c1-4-6-8-10-12-14-16-18-19-21-23-25-27-29-31-33-39(42)45-37(34-43-36(3)40)35-44-38(41)32-30-28-26-24-22-20-17-15-13-11-9-7-5-2/h12,14,18-19,37H,4-11,13,15-17,20-35H2,1-3H3"	"yes"	""	""
"10679"	"motixafortide"	""	"Peptide"	"yes"	""	""	""	"404859126"	"91865076"	""	""	""	""	""	""	""	""	"motixafortide"	"4F-Benzoyl-TN14003|Aphexda&reg;|BKT140|BL-8040|TF14016"	"NCCCC[C@@H]1NC(=O)[C@H](CCCNC(=O)N)NC(=O)[C@H](Cc2ccc(cc2)O)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H]2N(C(=O)[C@@H](NC1=O)CCCCN)CCC2)Cc1ccc(cc1)O)CCCNC(=N)N)CCCNC(=O)N)C(=O)N[C@H](C(=O)N)CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1ccc(cc1)F)CCCNC(=N)N)CCCNC(=N)N)Cc1ccc2c(c1)cccc2"	"JJVZSYKFCOBILL-MKMRYRNGSA-N"	"InChI=1S/C97H144FN33O19S2/c98-60-33-31-58(32-34-60)78(135)119-65(19-8-42-113-93(104)105)79(136)121-68(21-10-44-115-95(108)109)83(140)126-73(51-56-25-30-57-14-1-2-15-59(57)48-56)87(144)130-75-53-152-151-52-74(88(145)118-63(77(101)134)18-7-41-112-92(102)103)129-84(141)69(23-12-46-117-97(111)150)122-81(138)66(20-9-43-114-94(106)107)124-86(143)72(50-55-28-37-62(133)38-29-55)128-90(147)76-24-13-47-131(76)91(148)70(17-4-6-40-100)125-82(139)64(16-3-5-39-99)120-80(137)67(22-11-45-116-96(110)149)123-85(142)71(127-89(75)146)49-54-26-35-61(132)36-27-54/h1-2,14-15,25-38,48,63-76,132-133H,3-13,16-24,39-47,49-53,99-100H2,(H2,101,134)(H,118,145)(H,119,135)(H,120,137)(H,121,136)(H,122,138)(H,123,142)(H,124,143)(H,125,139)(H,126,140)(H,127,146)(H,128,147)(H,129,141)(H,130,144)(H4,102,103,112)(H4,104,105,113)(H4,106,107,114)(H4,108,109,115)(H3,110,116,149)(H3,111,117,150)/t63-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-/m0/s1"	"yes"	""	""
"9026"	"motolimod"	""	"Synthetic organic"	""	""	""	""	"315661111"	"16049404"	""	""	"CHEMBL3301618"	""	""	""	""	"2-amino-N,N-dipropyl-8-[4-(pyrrolidine-1-carbonyl)phenyl]-3H-1-benzazepine-4-carboxamide"	"motolimod"	"VTX-2337"	"CCCN(C(=O)C1=Cc2ccc(cc2N=C(C1)N)c1ccc(cc1)C(=O)N1CCCC1)CCC"	"QSPOQCXMGPDIHI-UHFFFAOYSA-N"	"InChI=1S/C28H34N4O2/c1-3-13-31(14-4-2)28(34)24-17-23-12-11-22(18-25(23)30-26(29)19-24)20-7-9-21(10-8-20)27(33)32-15-5-6-16-32/h7-12,17-18H,3-6,13-16,19H2,1-2H3,(H2,29,30)"	"yes"	""	""
"7675"	"moxetumomab pasudotox"	""	"Antibody"	"yes"	""	""	""	"223366010"	""	""	""	"CHEMBL1743043"	""	""	""	""	""	"moxetumomab pasudotox"	"CAT-8015|GCR-8015|HA22|Lumoxiti&reg;|moxetumomab pasudotox-tdfk"	""	""	""	"yes"	""	""
"9580"	"MPI-0485520"	""	"Synthetic organic"	""	""	""	""	"336446966"	"56646218"	""	""	"CHEMBL3650697"	""	""	""	""	""	""	"MPC-9528|MPI-485520"	"N#Cc1cc(ccc1N1CCCC1)c1ccnc(n1)Nc1ccc2c(c1)CC(=O)N2"	"DHPSFJYFPJRCTN-UHFFFAOYSA-N"	"InChI=1S/C23H20N6O/c24-14-17-11-15(3-6-21(17)29-9-1-2-10-29)20-7-8-25-23(28-20)26-18-4-5-19-16(12-18)13-22(30)27-19/h3-8,11-12H,1-2,9-10,13H2,(H,27,30)(H,25,26,28)"	"yes"	""	""
"9897"	"MPPA"	""	"Synthetic organic"	""	""	""	""	"363894191"	"133081968"	""	""	""	""	""	""	""	"N-{[4-methoxy-2-(trifluoromethyl)phenyl]methyl}-1-propanoylpiperidine-4-carboxamide"	""	"inhibitor 23 [PMID: 29614224]"	"CCC(=O)N1CCC(CC1)C(=O)NCc1ccc(cc1C(F)(F)F)OC"	"IJNCJYJSEFDKFC-UHFFFAOYSA-N"	"InChI=1S/C18H23F3N2O3/c1-3-16(24)23-8-6-12(7-9-23)17(25)22-11-13-4-5-14(26-2)10-15(13)18(19,20)21/h4-5,10,12H,3,6-9,11H2,1-2H3,(H,22,25)"	"yes"	""	""
"10521"	"MRI-1867"	""	"Synthetic organic"	""	""	""	""	"387065603"	"132937648"	""	""	""	""	""	""	""	"(4S)-N-(1-aminoethylidene)-5-(4-chlorophenyl)-N'-(4-chlorophenyl)sulfonyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide"	""	"(-)-MRI-1867|MRI1867"	"Clc1ccc(cc1)C1=NN(C[C@@H]1c1ccccc1)/C(=N/S(=O)(=O)c1ccc(cc1)Cl)/N=C(\N)/C"	"GZPQTZIUWCQXCF-JOCHJYFZSA-N"	"InChI=1S/C24H21Cl2N5O2S/c1-16(27)28-24(30-34(32,33)21-13-11-20(26)12-14-21)31-15-22(17-5-3-2-4-6-17)23(29-31)18-7-9-19(25)10-8-18/h2-14,22H,15H2,1H3,(H2,27,28,30)/t22-/m1/s1"	"yes"	""	""
"9080"	"MRL-248"	""	"Synthetic organic"	""	""	""	""	"315661165"	"121231396"	""	""	""	""	""	""	""	"4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H,3aH,7aH-pyrazolo[4,3-b]pyridin-3-yl}-3-fluorobenzoic acid"	""	""	"OC(=O)c1ccc(c(c1)F)C1=NN(C2C1N=CC=C2)C(=O)c1c(Cl)cccc1C(F)(F)F"	"ODEANEWMWSRFHI-UHFFFAOYSA-N"	"InChI=1S/C21H12ClF4N3O3/c22-13-4-1-3-12(21(24,25)26)16(13)19(30)29-15-5-2-8-27-18(15)17(28-29)11-7-6-10(20(31)32)9-14(11)23/h1-9,15,18H,(H,31,32)"	"yes"	""	""
"9079"	"MRL-367"	""	"Synthetic organic"	""	""	""	""	"315661164"	"121231395"	""	""	""	""	""	""	""	"4-{1-[2-chloro-6-(trifluoromethyl)benzoyl]-1H,3aH,7aH-pyrazolo[4,3-b]pyridin-3-yl}-5-fluoro-2-hydroxybenzoic acid"	""	""	"Fc1cc(C(=O)O)c(cc1C1=NN(C2C1N=CC=C2)C(=O)c1c(Cl)cccc1C(F)(F)F)O"	"LCOVNUGQIUYGLV-UHFFFAOYSA-N"	"InChI=1S/C21H12ClF4N3O4/c22-12-4-1-3-11(21(24,25)26)16(12)19(31)29-14-5-2-6-27-18(14)17(28-29)9-8-15(30)10(20(32)33)7-13(9)23/h1-8,14,18,30H,(H,32,33)"	"yes"	""	""
"10642"	"MRL-871"	""	"Synthetic organic"	""	""	""	""	"404859089"	"68159303"	""	""	"CHEMBL3598140"	""	""	""	""	"4-[1-[2-chloro-6-(trifluoromethyl)benzoyl]indazol-3-yl]benzoic acid"	""	"MRL871"	"OC(=O)c1ccc(cc1)c1nn(c2c1cccc2)C(=O)c1c(Cl)cccc1C(F)(F)F"	"DANLZOIRUUHIIX-UHFFFAOYSA-N"	"InChI=1S/C22H12ClF3N2O3/c23-16-6-3-5-15(22(24,25)26)18(16)20(29)28-17-7-2-1-4-14(17)19(27-28)12-8-10-13(11-9-12)21(30)31/h1-11H,(H,30,31)"	"yes"	""	""
"1753"	"MRS2578"	""	"Synthetic organic"	""	""	""	""	"135650661"	"16078986"	""	""	"CHEMBL1321988"	""	""	""	""	"3-(3-isothiocyanatophenyl)-1-[4-[(3-isothiocyanatophenyl)carbamothioylamino]butyl]thiourea"	""	"MRS 2578|MRS-2578"	"S=C=Nc1cccc(c1)NC(=S)NCCCCNC(=S)Nc1cccc(c1)N=C=S"	"QOHNRGHTJPFMSL-UHFFFAOYSA-N"	"InChI=1S/C20H20N6S4/c27-13-23-15-5-3-7-17(11-15)25-19(29)21-9-1-2-10-22-20(30)26-18-8-4-6-16(12-18)24-14-28/h3-8,11-12H,1-2,9-10H2,(H2,21,25,29)(H2,22,26,30)"	"yes"	""	""
"9998"	"MRS4458"	""	"Synthetic organic"	""	""	""	""	"374883885"	"134611895"	""	""	""	""	""	""	""	"3-{5-[(3-aminopropyl)carbamoyl]thiophen-2-yl}-5-{4-[4-(trifluoromethyl)phenyl]-1H-1,2,3-triazol-1-yl}benzoic acid"	""	"compound 20 [Yu <i>et al.</i>, 2018]"	"NCCCNC(=O)c1ccc(s1)c1cc(cc(c1)n1nnc(c1)c1ccc(cc1)C(F)(F)F)C(=O)O"	"VYXSDIPOJBFWHQ-UHFFFAOYSA-N"	"InChI=1S/C24H20F3N5O3S/c25-24(26,27)17-4-2-14(3-5-17)19-13-32(31-30-19)18-11-15(10-16(12-18)23(34)35)20-6-7-21(36-20)22(33)29-9-1-8-28/h2-7,10-13H,1,8-9,28H2,(H,29,33)(H,34,35)"	"yes"	""	""
"9999"	"MRS4478"	""	"Synthetic organic"	""	""	""	""	"374883886"	"134611896"	""	""	""	""	""	""	""	"4'-carbamoyl-5-{4-[4-(trifluoromethyl)phenyl]-1H-1,2,3-triazol-1-yl}-[1,1'-biphenyl]-3-carboxylic acid"	""	"compound 30 [Yu <i>et al.</i>, 2018]"	"OC(=O)c1cc(cc(c1)n1nnc(c1)c1ccc(cc1)C(F)(F)F)c1ccc(cc1)C(=O)N"	"ODSCFSVBFVSJFO-UHFFFAOYSA-N"	"InChI=1S/C23H15F3N4O3/c24-23(25,26)18-7-5-14(6-8-18)20-12-30(29-28-20)19-10-16(9-17(11-19)22(32)33)13-1-3-15(4-2-13)21(27)31/h1-12H,(H2,27,31)(H,32,33)"	"yes"	""	""
"8062"	"MRT67307"	""	"Synthetic organic"	""	""	""	""	"249565742"	"44464263"	""	""	""	""	""	""	""	"N-[3-[[5-cyclopropyl-2-[3-(morpholin-4-ylmethyl)anilino]pyrimidin-4-yl]amino]propyl]cyclobutanecarboxamide"	""	"MRT-67307"	"O=C(C1CCC1)NCCCNc1nc(ncc1C1CC1)Nc1cccc(c1)CN1CCOCC1"	"UKBGBACORPRCGG-UHFFFAOYSA-N"	"InChI=1S/C26H36N6O2/c33-25(21-5-2-6-21)28-11-3-10-27-24-23(20-8-9-20)17-29-26(31-24)30-22-7-1-4-19(16-22)18-32-12-14-34-15-13-32/h1,4,7,16-17,20-21H,2-3,5-6,8-15,18H2,(H,28,33)(H2,27,29,30,31)"	"yes"	""	""
"9339"	"mucosal addressin cell adhesion molecule 1"	"Human"	"Peptide"	""	""	""	""	"328083442"	""	"Q13477"	"ENSG00000099866"	""	""	""	""	""	""	""	"addressin|MAdCAM-1|MAdCAM1"	""	""	""	"yes"	""	""
"14395"	"mufemilast"	""	"Synthetic organic"	"yes"	""	""	""	"523352187"	"137355584"	""	""	"CHEMBL5095240"	""	""	""	""	"N-[5-[(1S)-1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4,6-dioxothieno[3,4-c]pyrrol-3-yl]acetamide"	"mufemilast"	"Hemay005|Momishin&reg; (China)"	"CCOC1=C(C=CC(=C1)[C@@H](CS(=O)(=O)C)N2C(=O)C3=CSC(=C3C2=O)NC(=O)C)OC"	"PRSNGWLHNWGOKD-CQSZACIVSA-N"	"InChI=1S/C20H22N2O7S2/c1-5-29-16-8-12(6-7-15(16)28-3)14(10-31(4,26)27)22-19(24)13-9-30-18(21-11(2)23)17(13)20(22)25/h6-9,14H,5,10H2,1-4H3,(H,21,23)/t14-/m1/s1"	"yes"	""	""
"6889"	"muromonab-CD3"	""	"Antibody"	"yes"	"yes"	""	""	"178103471"	""	""	""	""	""	""	""	""	""	"muromonab-CD3"	"L04AA02|OKT-3|Orthoclone Okt3&reg;"	""	""	""	"yes"	""	""
"10524"	"MW150"	""	"Synthetic organic"	""	""	""	""	"387065606"	"86270361"	""	""	""	""	""	""	""	"6-(4-methylpiperazin-1-yl)-3-naphthalen-2-yl-4-pyridin-4-ylpyridazine"	""	"compound 11 [PMID: 30978288]|compound 27 [WO2014145485A2]|compound 8 [PMID: 25676389]|MW-150|MW01-18-150SRM"	"CN1CCN(CC1)c1nnc(c(c1)c1ccncc1)c1ccc2c(c1)cccc2"	"CIIVUDIZZJLXCN-UHFFFAOYSA-N"	"InChI=1S/C24H23N5/c1-28-12-14-29(15-13-28)23-17-22(19-8-10-25-11-9-19)24(27-26-23)21-7-6-18-4-2-3-5-20(18)16-21/h2-11,16-17H,12-15H2,1H3"	"yes"	""	""
"6831"	"mycophenolate mofetil"	""	"Synthetic organic"	"yes"	""	""	""	"178103437"	"5281078"	""	""	"CHEMBL1456"	""	""	""	""	"2-(morpholin-4-yl)ethyl (4E)-6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoate"	""	"Cellcept&reg;|RS-61443|RS-61443-190"	"COc1c(C/C=C(/CCC(=O)OCCN2CCOCC2)\C)c(O)c2c(c1C)COC2=O"	"RTGDFNSFWBGLEC-SYZQJQIISA-N"	"InChI=1S/C23H31NO7/c1-15(5-7-19(25)30-13-10-24-8-11-29-12-9-24)4-6-17-21(26)20-18(14-31-23(20)27)16(2)22(17)28-3/h4,26H,5-14H2,1-3H3/b15-4+"	"yes"	""	""
"7245"	"nabumetone"	""	"Synthetic organic"	"yes"	""	""	""	"178103819"	"4409"	""	""	"CHEMBL1070"	""	""	""	""	"4-(6-methoxynaphthalen-2-yl)butan-2-one"	"nabumetone"	"BRL-14777|Relafen&reg;"	"COc1ccc2c(c1)ccc(c2)CCC(=O)C"	"BLXXJMDCKKHMKV-UHFFFAOYSA-N"	"InChI=1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3"	"yes"	""	""
"13502"	"nacresertib"	""	"Synthetic organic"	""	""	""	""	"500839912"	"156710490"	""	""	""	""	""	""	""	"N-[2-(4-hydroxy-4-methylcyclohexyl)-6-methoxyindazol-5-yl]-6-methyl-1-oxidopyridin-1-ium-2-carboxamide"	"nacresertib"	"compound 001 [WO2021057785]"	"[H][C@@]1(CC[C@](C)(O)CC1)N2C=C3C=C(NC(=O)C4=CC=CC(C)=[N+]4[O-])C(OC)=CC3=N2"	"XYPANWHZPSKPMX-CIEDQVTBSA-N"	"InChI=1S/C22H26N4O4/c1-14-5-4-6-19(26(14)29)21(27)23-18-11-15-13-25(24-17(15)12-20(18)30-3)16-7-9-22(2,28)10-8-16/h4-6,11-13,16,28H,7-10H2,1-3H3,(H,23,27)/t16-,22-"	"yes"	""	""
"10370"	"namilumab"	""	"Antibody"	""	""	""	""	"384403650"	""	""	""	""	""	""	""	""	""	"namilumab"	"AMG203|MT203"	""	""	""	"yes"	""	""
"9551"	"naproxcinod"	""	"Synthetic organic"	""	""	""	""	"336446937"	"9884642"	""	""	"CHEMBL2103831"	""	""	""	""	"4-nitrooxybutyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate"	"naproxcinod"	"AZD-3582|AZD3582|HCT-3012|NO-naproxen"	"COc1ccc2c(c1)ccc(c2)[C@@H](C(=O)OCCCCO[N+](=O)[O-])C"	"AKFJWRDCWYYTIG-ZDUSSCGKSA-N"	"InChI=1S/C18H21NO6/c1-13(18(20)24-9-3-4-10-25-19(21)22)14-5-6-16-12-17(23-2)8-7-15(16)11-14/h5-8,11-13H,3-4,9-10H2,1-2H3/t13-/m0/s1"	"yes"	""	""
"5230"	"naproxen"	""	"Synthetic organic"	"yes"	""	""	""	"178101914"	"156391"	""	""	"CHEMBL154"	""	""	""	""	"(2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid"	"naproxen"	"(<i>S</i>)-naproxen|Aleve&reg;|Naprosy&reg;"	"COc1ccc2c(c1)ccc(c2)[C@@H](C(=O)O)C"	"CMWTZPSULFXXJA-VIFPVBQESA-N"	"InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1"	"yes"	""	""
"9948"	"naptumomab estafenatox"	""	"Antibody"	""	""	""	""	"374883835"	""	""	""	"CHEMBL1743045"	""	""	""	""	""	""	"ABR-217620|ABR217620|Anyara (proposed trade name)|TTS CD3|TTS-CD3"	""	""	""	"yes"	""	""
"9949"	"naratuximab emtansine"	""	"Antibody"	""	""	""	""	"374883836"	""	""	""	""	""	""	""	""	""	"naratuximab emtansine"	"IMGN-529|IMGN529|K7153A-SMCC-DM1"	""	""	""	"yes"	""	""
"6591"	"natalizumab"	""	"Antibody"	"yes"	""	""	""	"178103204"	""	""	""	""	""	""	""	""	""	"natalizumab"	"AN100226|anti-alpha4 integrin|anti-VLA4|Tysabri&reg;"	""	""	""	"yes"	""	""
"11142"	"Natural cytotoxicity triggering receptor 3 ligand 1"	"Human"	"Peptide"	""	""	""	""	"434122202"	""	"Q68D85"	"ENSG00000188211"	""	""	""	""	""	""	""	"B7-H6|B7H6"	""	""	""	"yes"	""	""
"9463"	"navamepent"	""	"Synthetic organic"	""	""	""	""	"329968403"	"46926878"	""	""	""	""	""	""	""	"propan-2-yl (5S,8E,10E,12R)-5,12-dihydroxypentadeca-8,10-dien-6,14-diynoate"	"navamepent"	"RX-10045"	"C#CC[C@H](/C=C/C=C/C#C[C@H](CCCC(=O)OC(C)C)O)O"	"ZVOCIIHCJJEFRQ-BHXBHYJPSA-N"	"InChI=1S/C18H24O4/c1-4-10-16(19)11-7-5-6-8-12-17(20)13-9-14-18(21)22-15(2)3/h1,5-7,11,15-17,19-20H,9-10,13-14H2,2-3H3/b6-5+,11-7+/t16-,17-/m1/s1"	"yes"	""	""
"8497"	"navarixin"	""	"Synthetic organic"	""	""	""	""	"252166705"	"9865554"	""	""	"CHEMBL216981"	""	""	""	""	"2-hydroxy-N,N-dimethyl-3-[[2-[[(1R)-1-(5-methylfuran-2-yl)propyl]amino]-3,4-dioxo-1-cyclobutenyl]amino]benzamide"	"navarixin"	"MK-7123|MK7123|SCH-527123|SCH527123"	"CC[C@H](c1ccc(o1)C)NC1=C(C(=O)C1=O)Nc1cccc(c1O)C(=O)N(C)C"	"RXIUEIPPLAFSDF-CYBMUJFWSA-N"	"InChI=1S/C21H23N3O5/c1-5-13(15-10-9-11(2)29-15)22-16-17(20(27)19(16)26)23-14-8-6-7-12(18(14)25)21(28)24(3)4/h6-10,13,22-23,25H,5H2,1-4H3/t13-/m1/s1"	"yes"	""	""
"9019"	"navoximod"	""	"Synthetic organic"	""	""	""	""	"315661104"	"66558287"	""	""	"CHEMBL3629569"	""	""	""	""	"1-cyclohexyl-2-(5H-imidazo[5,1-a]isoindol-5-yl)ethanol"	"navoximod"	"GDC-0919|NLG-919|NLG919|RG6078"	"OC(C1CCCCC1)CC1c2ccccc2c2n1cnc2"	"YTRRAUACYORZLX-UHFFFAOYSA-N"	"InChI=1S/C18H22N2O/c21-18(13-6-2-1-3-7-13)10-16-14-8-4-5-9-15(14)17-11-19-12-20(16)17/h4-5,8-9,11-13,16,18,21H,1-3,6-7,10H2"	"yes"	""	""
"839"	"NBI-74330"	""	"Synthetic organic"	""	""	""	""	"135650695"	"10167713"	""	""	""	""	""	""	""	"N-[1-[3-(4-ethoxyphenyl)-4-oxopyrido[2,3-d]pyrimidin-2-yl]ethyl]-2-[4-fluoro-3-(trifluoromethyl)phenyl]-N-(pyridin-3-ylmethyl)acetamide"	""	"(&plusmn;)-NBI 74330|NBI74330"	"CCOc1ccc(cc1)n1c(nc2c(c1=O)cccn2)C(N(C(=O)Cc1ccc(c(c1)C(F)(F)F)F)Cc1cccnc1)C"	"XMRGQUDUVGRCBS-UHFFFAOYSA-N"	"InChI=1S/C32H27F4N5O3/c1-3-44-24-11-9-23(10-12-24)41-30(39-29-25(31(41)43)7-5-15-38-29)20(2)40(19-22-6-4-14-37-18-22)28(42)17-21-8-13-27(33)26(16-21)32(34,35)36/h4-16,18,20H,3,17,19H2,1-2H3"	"yes"	""	""
"10373"	"NC1"	""	"Synthetic organic"	""	""	""	""	"384403653"	"6534740"	""	""	""	""	""	""	""	"4-[[4-[(Z)-[2-(4-ethoxycarbonylphenyl)imino-3-methyl-4-oxo-1,3-thiazolidin-5-ylidene]methyl]-2-methoxyphenoxy]methyl]benzoic acid"	""	""	"CCOC(=O)c1ccc(cc1)N=C1S/C(=C\c2ccc(c(c2)OC)OCc2ccc(cc2)C(=O)O)/C(=O)N1C"	"MEYCXOYFLJPZOT-FXALAWDZSA-N"	"InChI=1S/C29H26N2O7S/c1-4-37-28(35)21-10-12-22(13-11-21)30-29-31(2)26(32)25(39-29)16-19-7-14-23(24(15-19)36-3)38-17-18-5-8-20(9-6-18)27(33)34/h5-16H,4,17H2,1-3H3,(H,33,34)/b25-16-,30-29?"	"yes"	""	""
"9018"	"NCX-4016"	""	"Synthetic organic"	""	""	""	""	"315661103"	"119032"	""	""	"CHEMBL374385"	""	""	""	""	"[3-(nitrooxymethyl)phenyl] 2-acetyloxybenzoate"	""	"NCX 4016|NCX4016|nitric oxide-releasing aspirin|nitroaspirin"	"[O-][N+](=O)OCc1cccc(c1)OC(=O)c1ccccc1OC(=O)C"	"IOJUJUOXKXMJNF-UHFFFAOYSA-N"	"InChI=1S/C16H13NO7/c1-11(18)23-15-8-3-2-7-14(15)16(19)24-13-6-4-5-12(9-13)10-22-17(20)21/h2-9H,10H2,1H3"	"yes"	""	""
"8082"	"ND-2110"	""	"Synthetic organic"	""	""	""	""	"249565762"	"68115559"	""	""	""	""	""	""	""	"2-[(3R)-12-{[(1r,4r)-4-(morpholin-4-yl)cyclohexyl]oxy}-7-thia-9,11-diazatricyclo[6.4.0.0²,⁶]dodeca-1(12),2(6),8,10-tetraen-3-yl]acetamide"	""	""	"NC(=O)C[C@H]1CCc2c1c1c(ncnc1s2)O[C@@H]1CC[C@H](CC1)N1CCOCC1"	"VZOLINZYKOLXAC-RBSFLKMASA-N"	"InChI=1S/C21H28N4O3S/c22-17(26)11-13-1-6-16-18(13)19-20(23-12-24-21(19)29-16)28-15-4-2-14(3-5-15)25-7-9-27-10-8-25/h12-15H,1-11H2,(H2,22,26)/t13-,14-,15-/m1/s1"	"yes"	""	""
"8083"	"ND-2158"	""	"Synthetic organic"	""	""	""	""	"249565763"	"86343751"	""	""	""	""	""	""	""	"(2S)-2-hydroxy-3-[(3R)-12-{[(1r,4r)-4-(morpholin-4-yl)cyclohexyl]oxy}-7-thia-9,11-diazatricyclo[6.4.0.0²,⁶]dodeca-1(12),2(6),8,10-tetraen-3-yl]propanamide"	""	""	"NC(=O)[C@H](C[C@H]1CCc2c1c1c(ncnc1s2)O[C@@H]1CC[C@H](CC1)N1CCOCC1)O"	"ZSMULWAVKYFPSS-FPCVCCKLSA-N"	"InChI=1S/C22H30N4O4S/c23-20(28)16(27)11-13-1-6-17-18(13)19-21(24-12-25-22(19)31-17)30-15-4-2-14(3-5-15)26-7-9-29-10-8-26/h12-16,27H,1-11H2,(H2,23,28)/t13-,14-,15-,16+/m1/s1"	"yes"	""	""
"13009"	"NDT-19795"	""	"Synthetic organic"	""	""	""	""	"485206130"	"137465770"	""	""	""	""	""	""	""	"(2R)-2-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyloxy)-3-pyrimidin-2-ylpropanoic acid"	""	"NDT19795"	"C1CCC2=C(C=3CCCC3C=C12)NC(=O)O[C@@H](C(=O)O)CC4=NC=CC=N4"	"OYXWZQHGHRELLY-MRXNPFEDSA-N"	"InChI=1S/C20H21N3O4/c24-19(25)16(11-17-21-8-3-9-22-17)27-20(26)23-18-14-6-1-4-12(14)10-13-5-2-7-15(13)18/h3,8-10,16H,1-2,4-7,11H2,(H,23,26)(H,24,25)/t16-/m1/s1"	"yes"	""	""
"9746"	"NDT9513727"	""	"Synthetic organic"	""	""	""	""	"354702219"	"10210160"	""	""	""	""	""	""	""	"N,N-bis(1,3-benzodioxol-5-ylmethyl)-1-[3-butyl-2,5-di(phenyl)imidazol-4-yl]methanamine"	""	"NDT 9513727|NDT-9513727"	"CCCCn1c(CN(Cc2ccc3c(c2)OCO3)Cc2ccc3c(c2)OCO3)c(nc1c1ccccc1)c1ccccc1"	"ITACCRHKSPSKKL-UHFFFAOYSA-N"	"InChI=1S/C36H35N3O4/c1-2-3-18-39-30(35(28-10-6-4-7-11-28)37-36(39)29-12-8-5-9-13-29)23-38(21-26-14-16-31-33(19-26)42-24-40-31)22-27-15-17-32-34(20-27)43-25-41-32/h4-17,19-20H,2-3,18,21-25H2,1H3"	"yes"	""	""
"10206"	"NE 52-QQ57"	""	"Synthetic organic"	""	""	""	""	"381744888"	"68379135"	""	""	"CHEMBL3675743"	""	""	""	""	"2-[4-[(2-ethyl-5,7-dimethylpyrazolo[1,5-a]pyrimidin-3-yl)methyl]phenyl]-5-piperidin-4-yl-1,3,4-oxadiazole"	""	"example 35 [WO2012131633A1]|GPR4 antagonist 13|NE52-QQ57"	"CCc1nn2c(c1Cc1ccc(cc1)c1nnc(o1)C1CCNCC1)nc(cc2C)C"	"HXPQWNPLNIEJOW-UHFFFAOYSA-N"	"InChI=1S/C24H28N6O/c1-4-21-20(22-26-15(2)13-16(3)30(22)29-21)14-17-5-7-18(8-6-17)23-27-28-24(31-23)19-9-11-25-12-10-19/h5-8,13,19,25H,4,9-12,14H2,1-3H3"	"yes"	""	""
"9750"	"necrostatin-1"	""	"Synthetic organic"	""	""	""	""	"354702223"	"2828334"	""	""	"CHEMBL195008"	""	""	""	""	"5-(1H-indol-3-ylmethyl)-3-methyl-2-sulfanylideneimidazolidin-4-one"	""	"methyl-thiohydantoin-tryptophan|MTH-DL-tryptophan|MTH-trp|nec-1|Necrostatin 1"	"S=C1NC(C(=O)N1C)Cc1c[nH]c2c1cccc2"	"TXUWMXQFNYDOEZ-UHFFFAOYSA-N"	"InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)"	"yes"	""	""
"9751"	"necrostatin-1s"	""	"Synthetic organic"	""	""	""	""	"354702224"	"643953"	""	""	"CHEMBL381230"	""	""	""	""	"5-[(7-chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione"	""	"7-Cl-O-Nec-1|nec-1s|necrostatin 2 racemate"	"CN1C(=O)C(NC1=O)Cc1c[nH]c2c1cccc2Cl"	"WIKGAEMMNQTUGL-UHFFFAOYSA-N"	"InChI=1S/C13H12ClN3O2/c1-17-12(18)10(16-13(17)19)5-7-6-15-11-8(7)3-2-4-9(11)14/h2-4,6,10,15H,5H2,1H3,(H,16,19)"	"yes"	""	""
"7607"	"nedocromil"	""	"Synthetic organic"	"yes"	""	""	""	"223365942"	"50294"	""	""	"CHEMBL746"	""	""	""	""	"9-ethyl-4,6-dioxo-10-propylpyrano[5,6-g]quinoline-2,8-dicarboxylic acid"	"nedocromil"	"FPL-59002|nedocromil sodium|Rapitil&reg;|Tilade&reg;"	"CCCc1c2oc(cc(=O)c2cc2c1n(CC)c(cc2=O)C(=O)O)C(=O)O"	"RQTOOFIXOKYGAN-UHFFFAOYSA-N"	"InChI=1S/C19H17NO7/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26)"	"yes"	""	""
"5719"	"neflamapimod"	""	"Synthetic organic"	""	""	""	""	"178102345"	"3038525"	""	""	"CHEMBL119385"	""	""	""	""	"5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyridazino[6,1-f]pyrimidin-6-one"	"neflamapimod"	"VD-31745|VRT-031745|VX 745|VX-745"	"Fc1ccc(c(c1)F)Sc1ccc2n(n1)cnc(=O)c2c1c(Cl)cccc1Cl"	"VEPKQEUBKLEPRA-UHFFFAOYSA-N"	"InChI=1S/C19H9Cl2F2N3OS/c20-11-2-1-3-12(21)17(11)18-14-5-7-16(25-26(14)9-24-19(18)27)28-15-6-4-10(22)8-13(15)23/h1-9H"	"yes"	""	""
"9425"	"nemiralisib"	""	"Synthetic organic"	""	""	""	""	"328083525"	"49784002"	""	""	"CHEMBL2216859"	""	""	""	""	"2-[6-(1H-indol-4-yl)-1H-indazol-4-yl]-5-[(4-propan-2-ylpiperazin-1-yl)methyl]-1,3-oxazole"	"nemiralisib"	"compound 2 [PMID: 26301626]|GSK-2269557|GSK2269557"	"CC(N1CCN(CC1)Cc1cnc(o1)c1cc(cc2c1cn[nH]2)c1cccc2c1cc[nH]2)C"	"MCIDWGZGWVSZMK-UHFFFAOYSA-N"	"InChI=1S/C26H28N6O/c1-17(2)32-10-8-31(9-11-32)16-19-14-28-26(33-19)22-12-18(13-25-23(22)15-29-30-25)20-4-3-5-24-21(20)6-7-27-24/h3-7,12-15,17,27H,8-11,16H2,1-2H3,(H,29,30)"	"yes"	""	""
"8720"	"nemolizumab"	""	"Antibody"	"yes"	""	""	""	"252827378"	""	""	""	""	""	""	""	""	""	"nemolizumab"	"CD14152|CIM 331|CIM331|Mitchga&reg;|Nemluvio&reg;"	""	""	""	"yes"	""	""
"9137"	"neoceptin-3"	""	"Synthetic organic"	""	""	""	""	"315661222"	"77461013"	""	""	""	""	""	""	""	"tert-butyl (2S)-2-[[4-amino-3-[2-(4-hydroxyphenyl)ethyl]benzoyl]amino]-4-phenylbutanoate"	""	""	"O=C([C@@H](NC(=O)c1ccc(c(c1)CCc1ccc(cc1)O)N)CCc1ccccc1)OC(C)(C)C"	"OACODUCFPHHCIH-SANMLTNESA-N"	"InChI=1S/C29H34N2O4/c1-29(2,3)35-28(34)26(18-12-20-7-5-4-6-8-20)31-27(33)23-14-17-25(30)22(19-23)13-9-21-10-15-24(32)16-11-21/h4-8,10-11,14-17,19,26,32H,9,12-13,18,30H2,1-3H3,(H,31,33)/t26-/m0/s1"	"yes"	""	""
"9138"	"neoceptin-4"	""	"Synthetic organic"	""	""	""	""	"315661223"	"121231399"	""	""	""	""	""	""	""	"tert-butyl (2R)-2-({4-amino-3-[(4-hydroxyphenyl)methoxy]phenyl}formamido)-4-phenylbutanoate"	""	""	"O=C([C@H](NC(=O)c1ccc(c(c1)OCc1ccc(cc1)O)N)CCc1ccccc1)OC(C)(C)C"	"NRHPXDROGIVILZ-XMMPIXPASA-N"	"InChI=1S/C28H32N2O5/c1-28(2,3)35-27(33)24(16-11-19-7-5-4-6-8-19)30-26(32)21-12-15-23(29)25(17-21)34-18-20-9-13-22(31)14-10-20/h4-10,12-15,17,24,31H,11,16,18,29H2,1-3H3,(H,30,32)/t24-/m1/s1"	"yes"	""	""
"12518"	"nerandomilast"	""	"Synthetic organic"	"yes"	""	""	""	"479821308"	"166177189"	""	""	""	""	""	""	""	"[1-[[(5R)-2-[4-(5-chloropyrimidin-2-yl)piperidin-1-yl]-5-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-4-yl]amino]cyclobutyl]methanol"	""	"BI 1015550|BI-1015550|BI1015550"	"OCC1(CCC1)NC2=NC(=NC3=C2[S@](=O)CC3)N4CCC(CC4)C5=NC=C(Cl)C=N5"	"UHYCLWAANUGUMN-SSEXGKCCSA-N"	"InChI=1S/C20H25ClN6O2S/c21-14-10-22-17(23-11-14)13-2-7-27(8-3-13)19-24-15-4-9-30(29)16(15)18(25-19)26-20(12-28)5-1-6-20/h10-11,13,28H,1-9,12H2,(H,24,25,26)/t30-/m1/s1"	"yes"	""	""
"9419"	"Nexinhib20"	""	"Synthetic organic"	""	""	""	""	"328083519"	"5715188"	""	""	"CHEMBL1459140"	""	""	""	""	"(Z)-4,4-dimethyl-1-(3-nitrophenyl)-2-(1,2,4-triazol-1-yl)pent-1-en-3-one"	""	""	"O=C(C(C)(C)C)/C(=C/c1cccc(c1)[N+](=O)[O-])/n1cncn1"	"VKSOIYNNOFGGES-JYRVWZFOSA-N"	"InChI=1S/C15H16N4O3/c1-15(2,3)14(20)13(18-10-16-9-17-18)8-11-5-4-6-12(7-11)19(21)22/h4-10H,1-3H3/b13-8-"	"yes"	""	""
"11304"	"nezulcitinib"	""	"Synthetic organic"	""	""	""	""	"434321739"	"146421275"	""	""	""	""	""	""	""	"[3-(dimethylamino)azetidin-1-yl]-[(6S)-2-[6-(2-ethyl-4-hydroxyphenyl)-1H-indazol-3-yl]-5-propan-2-yl-3,4,6,7-tetrahydroimidazo[4,5-c]pyridin-6-yl]methanone"	"nezulcitinib"	"example 1 [WO2020051105A1]"	"CCc1cc(O)ccc1c1ccc2c(c1)[nH]nc2c1nc2c([nH]1)C[C@H](N(C2)C(C)C)C(=O)N1CC(C1)N(C)C"	"VQIIUJSNIKEMCK-MHZLTWQESA-N"	"InChI=1S/C30H37N7O2/c1-6-18-11-21(38)8-10-22(18)19-7-9-23-24(12-19)33-34-28(23)29-31-25-13-27(37(17(2)3)16-26(25)32-29)30(39)36-14-20(15-36)35(4)5/h7-12,17,20,27,38H,6,13-16H2,1-5H3,(H,31,32)(H,33,34)/t27-/m0/s1"	"yes"	""	""
"10519"	"NF-56-EJ40"	""	"Synthetic organic"	""	""	""	""	"387065601"	"138811017"	""	""	""	""	""	""	""	""	""	""	"CN1CCN(CC1)Cc1ccc(cc1)c1cccc(c1)C(=O)Nc1ccccc1CC(=O)O"	"UTWXDNZWMQAUKL-UHFFFAOYSA-N"	"InChI=1S/C27H29N3O3/c1-29-13-15-30(16-14-29)19-20-9-11-21(12-10-20)22-6-4-7-24(17-22)27(33)28-25-8-3-2-5-23(25)18-26(31)32/h2-12,17H,13-16,18-19H2,1H3,(H,28,33)(H,31,32)"	"yes"	""	""
"14338"	"NGT-201-12"	""	"Synthetic organic"	""	""	""	""	"523352130"	"177924586"	""	""	""	""	""	""	""	"3-[3-(1H-indol-5-yl)phenyl]piperidine-2,6-dione"	""	""	"O=C1CCC(C(=O)N1)C2=CC=CC(=C2)C3=CC=C4NC=CC4=C3"	"IWRHCGSRYITDIM-UHFFFAOYSA-N"	"InChI=1S/C19H16N2O2/c22-18-7-5-16(19(23)21-18)14-3-1-2-12(10-14)13-4-6-17-15(11-13)8-9-20-17/h1-4,6,8-11,16,20H,5,7H2,(H,21,22,23)"	"yes"	""	""
"13184"	"nibrozetone"	""	"Synthetic organic"	""	""	""	""	"491299966"	"15950826"	""	""	"CHEMBL3526802"	""	""	""	""	"2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone"	"nibrozetone"	"ABDNAZ|RRx-001|RRx001"	"BrCC(N1CC([N+]([O-])=O)([N+]([O-])=O)C1)=O"	"JODKFOVZURLVTG-UHFFFAOYSA-N"	"InChI=1S/C5H6BrN3O5/c6-1-4(10)7-2-5(3-7,8(11)12)9(13)14/h1-3H2"	"yes"	""	""
"2439"	"niflumic acid"	""	"Synthetic organic"	"yes"	""	""	""	"135650716"	"4488"	""	""	"CHEMBL63323"	""	""	""	""	"2-[[3-(trifluoromethyl)phenyl]amino]pyridine-3-carboxylic acid"	"niflumic acid"	""	"OC(=O)c1cccnc1Nc1cccc(c1)C(F)(F)F"	"JZFPYUNJRRFVQU-UHFFFAOYSA-N"	"InChI=1S/C13H9F3N2O2/c14-13(15,16)8-3-1-4-9(7-8)18-11-10(12(19)20)5-2-6-17-11/h1-7H,(H,17,18)(H,19,20)"	"yes"	""	""
"10947"	"NIK inhibitor 12f"	""	"Synthetic organic"	""	""	""	""	"405560388"	"146170996"	""	""	""	""	""	""	""	"4-(3-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-4-morpholinophenyl)-2-(thiazol-2-yl)but-3-yn-2-ol"	""	""	"CC(c1nccs1)(C#Cc1ccc(c(c1)Nc1ncnc2c1cc[nH]2)N1CCOCC1)O"	"KJMURTHIPWRIMC-UHFFFAOYSA-N"	"InChI=1S/C23H22N6O2S/c1-23(30,22-25-8-13-32-22)6-4-16-2-3-19(29-9-11-31-12-10-29)18(14-16)28-21-17-5-7-24-20(17)26-15-27-21/h2-3,5,7-8,13-15,30H,9-12H2,1H3,(H2,24,26,27,28)"	"yes"	""	""
"9964"	"NIK SMI1"	""	"Synthetic organic"	""	""	""	""	"374883851"	"117902000"	""	""	""	""	""	""	""	"6-(3-{2-[(3R)-3-hydroxy-1-methyl-2-oxopyrrolidin-3-yl]ethynyl}phenyl)-4-methoxypyridine-2-carboxamide"	""	""	"COc1cc(nc(c1)c1cccc(c1)C#C[C@]1(O)CCN(C1=O)C)C(=O)N"	"LQSHXYHWYGKAMX-FQEVSTJZSA-N"	"InChI=1S/C20H19N3O4/c1-23-9-8-20(26,19(23)25)7-6-13-4-3-5-14(10-13)16-11-15(27-2)12-17(22-16)18(21)24/h3-5,10-12,26H,8-9H2,1-2H3,(H2,21,24)/t20-/m0/s1"	"yes"	""	""
"7401"	"nimesulide"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178103973"	"4495"	""	""	"CHEMBL56367"	""	""	""	""	"N-[4-nitro-2-(phenoxy)phenyl]methanesulfonamide"	"nimesulide"	"R-805"	"[O-][N+](=O)c1ccc(c(c1)Oc1ccccc1)NS(=O)(=O)C"	"HYWYRSMBCFDLJT-UHFFFAOYSA-N"	"InChI=1S/C13H12N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h2-9,14H,1H3"	"yes"	""	""
"7335"	"nivolumab"	""	"Antibody"	"yes"	""	""	""	"178103907"	""	""	""	""	""	""	""	""	""	"nivolumab"	"BMS-936558|MDX-1106|ONO-4538|Opdivo&reg;"	""	""	""	"yes"	""	""
"14003"	"NK7-902"	""	"Synthetic organic"	""	""	""	""	"518520630"	"172639162"	""	""	""	""	""	""	""	"2-(2,6-dioxopiperidin-3-yl)-5-[(1S,2R,5S)-2-(ethylamino)-8-azabicyclo[3.2.1]octan-8-yl]isoindole-1,3-dione"	""	""	"CCN[C@@H]1CC[C@H]2CC[C@@H]1N2C3=CC4=C(C=C3)C(=O)N(C5CCC(=O)NC5=O)C4=O"	"QAKJEKTXKXAPBP-MGCURZBSSA-N"	"InChI=1S/C22H26N4O4/c1-2-23-16-7-4-12-5-8-17(16)25(12)13-3-6-14-15(11-13)22(30)26(21(14)29)18-9-10-19(27)24-20(18)28/h3,6,11-12,16-18,23H,2,4-5,7-10H2,1H3,(H,24,27,28)/t12-,16+,17-,18?/m0/s1"	"yes"	""	""
"14340"	"NLRP3 inhibitor 3 [PMID: 33255820]"	""	"Synthetic organic"	""	""	""	""	"523352132"	"142490216"	""	""	"CHEMBL6021067"	""	""	""	""	"1-[N-cyano-S-[5-(2-hydroxypropan-2-yl)-3-pyridinyl]sulfonimidoyl]-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea"	""	"example 65 [US11236045B2]"	"CC(C)(O)C1=CN=CC(=C1)S(=O)(NC(=O)NC2=C3CCCC3=CC4=C2CCC4)=NC#N"	"GLBXEHSDYAAEQT-UHFFFAOYSA-N"	"InChI=1S/C22H25N5O3S/c1-22(2,29)16-10-17(12-24-11-16)31(30,25-13-23)27-21(28)26-20-18-7-3-5-14(18)9-15-6-4-8-19(15)20/h9-12,29H,3-8H2,1-2H3,(H2,25,26,27,28,30)"	"yes"	""	""
"9520"	"N-methyl-2-pyrrolidone"	""	"Synthetic organic"	""	""	""	""	"336446906"	"13387"	""	""	""	""	""	""	""	"1-methylpyrrolidin-2-one"	""	"N-methyl-pyrrolidone|NMP"	"O=C1CCCN1C"	"SECXISVLQFMRJM-UHFFFAOYSA-N"	"InChI=1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3"	"yes"	""	""
"14360"	"nomelcitinib"	""	"Synthetic organic"	""	""	""	""	"523352152"	"170678247"	""	""	""	""	""	""	""	"4-[(5-chloro-3-methylsulfonyl-2-pyridinyl)amino]-6-(cyclopropanecarbonylamino)-N-(trideuteriomethyl)pyridazine-3-carboxamide"	"nomelcitinib"	"compound 52 [WO2022135430]|D-2570"	"[2H]C([2H])([2H])NC(=O)C1=NN=C(C=C1NC2=C(C=C(C=N2)Cl)S(=O)(=O)C)NC(=O)C3CC3"	"QZZGWCBTIULDRA-FIBGUPNXSA-N"	"InChI=1S/C16H17ClN6O4S/c1-18-16(25)13-10(6-12(22-23-13)21-15(24)8-3-4-8)20-14-11(28(2,26)27)5-9(17)7-19-14/h5-8H,3-4H2,1-2H3,(H,18,25)(H2,19,20,21,22,24)/i1D3"	"yes"	""	""
"13645"	"NP3-253"	""	"Synthetic organic"	""	""	""	""	"504705464"	"155284649"	""	""	""	""	""	""	""	"2-[6-[[(3R)-1-ethylpiperidin-3-yl]amino]pyridazin-3-yl]-3-methyl-5-(trifluoromethyl)phenol"	""	"compound 16 [PMID: 39574318]|NP3253"	"CCN1CCC[C@H](C1)NC2=CC=C(N=N2)C3=C(O)C=C(C=C3C)C(F)(F)F"	"UVVZGYXCKGWWCC-CQSZACIVSA-N"	"InChI=1S/C19H23F3N4O/c1-3-26-8-4-5-14(11-26)23-17-7-6-15(24-25-17)18-12(2)9-13(10-16(18)27)19(20,21)22/h6-7,9-10,14,27H,3-5,8,11H2,1-2H3,(H,23,25)/t14-/m1/s1"	"yes"	""	""
"14247"	"NP3-742"	""	"Synthetic organic"	""	""	""	""	"521588887"	"162679554"	""	""	"CHEMBL5499704"	""	""	""	""	"5-methyl-6-{2-methyl-1H-pyrrolo[2,3-b]pyridin-6-yl}-N-[(3R)-1-methylpiperidin-3-yl]pyridazin-3-amine"	""	""	"CN1CCC[C@H](C1)NC2=NN=C(C(C)=C2)C3=CC=C4C=C(C)NC4=N3"	"HNZKLSSKFNXSQZ-OAHLLOKOSA-N"	"InChI=1S/C19H24N6/c1-12-9-17(21-15-5-4-8-25(3)11-15)23-24-18(12)16-7-6-14-10-13(2)20-19(14)22-16/h6-7,9-10,15H,4-5,8,11H2,1-3H3,(H,20,22)(H,21,23)/t15-/m1/s1"	"yes"	""	""
"13271"	"NPT520-34"	""	"Synthetic organic"	""	""	""	""	"491300053"	"139507438"	""	""	""	""	""	""	""	"4-[4-[4-chloro-3-(trifluoromethyl)phenyl]sulfonylphenyl]-1H-1,2,4-triazole-5-thione"	""	"compound 1 [WO2019246454]"	"FC(F)(F)C1=C(Cl)C=CC(=C1)S(=O)(=O)C2=CC=C(C=C2)N3C=NNC3=S"	"BJWHWZOMLHXKPF-UHFFFAOYSA-N"	"InChI=1S/C15H9ClF3N3O2S2/c16-13-6-5-11(7-12(13)15(17,18)19)26(23,24)10-3-1-9(2-4-10)22-8-20-21-14(22)25/h1-8H,(H,21,25)"	"yes"	""	""
"8976"	"NS-398"	""	"Synthetic organic"	""	""	""	""	"310264756"	"4553"	""	""	"CHEMBL7162"	""	""	""	""	"N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide"	""	"NS 398"	"[O-][N+](=O)c1ccc(c(c1)OC1CCCCC1)NS(=O)(=O)C"	"KTDZCOWXCWUPEO-UHFFFAOYSA-N"	"InChI=1S/C13H18N2O5S/c1-21(18,19)14-12-8-7-10(15(16)17)9-13(12)20-11-5-3-2-4-6-11/h7-9,11,14H,2-6H2,1H3"	"yes"	""	""
"9318"	"NS6180"	""	"Synthetic organic"	""	""	""	""	"318164837"	"11837221"	""	""	""	""	""	""	""	"4-[[3-(trifluoromethyl)phenyl]methyl]-1,4-benzothiazin-3-one"	""	""	"O=C1CSc2c(N1Cc1cccc(c1)C(F)(F)F)cccc2"	"ZUIJXKLTUFCDGO-UHFFFAOYSA-N"	"InChI=1S/C16H12F3NOS/c17-16(18,19)12-5-3-4-11(8-12)9-20-13-6-1-2-7-14(13)22-10-15(20)21/h1-8H,9-10H2"	"yes"	""	""
"11383"	"NS6740"	""	"Synthetic organic"	""	""	""	""	"440816752"	"10021664"	""	""	"CHEMBL2380804"	""	""	""	""	"1,4-diazabicyclo[3.2.2]nonan-4-yl-[5-[3-(trifluoromethyl)phenyl]furan-2-yl]methanone"	""	"A-793394|A793394|NS-6740"	"O=C(N1CCN2CCC1CC2)c1ccc(o1)c1cccc(c1)C(F)(F)F"	"VSOWCIMCDKXVRC-UHFFFAOYSA-N"	"InChI=1S/C19H19F3N2O2/c20-19(21,22)14-3-1-2-13(12-14)16-4-5-17(26-16)18(25)24-11-10-23-8-6-15(24)7-9-23/h1-5,12,15H,6-11H2"	"yes"	""	""
"10364"	"NSC61610"	""	"Synthetic organic"	""	""	""	""	"384403644"	"247228"	""	""	"CHEMBL1562963"	""	""	""	""	"1-N,4-N-bis[3-(1H-benzimidazol-2-yl)phenyl]benzene-1,4-dicarboxamide"	""	""	"O=C(c1ccc(cc1)C(=O)Nc1cccc(c1)c1nc2c([nH]1)cccc2)Nc1cccc(c1)c1nc2c([nH]1)cccc2"	"WSXIJTIFOWCMIQ-UHFFFAOYSA-N"	"InChI=1S/C34H24N6O2/c41-33(35-25-9-5-7-23(19-25)31-37-27-11-1-2-12-28(27)38-31)21-15-17-22(18-16-21)34(42)36-26-10-6-8-24(20-26)32-39-29-13-3-4-14-30(29)40-32/h1-20H,(H,35,41)(H,36,42)(H,37,38)(H,39,40)"	"yes"	""	""
"10497"	"NSC80734"	""	"Synthetic organic"	""	""	""	""	"387065579"	"255329"	""	""	"CHEMBL1304177"	""	""	""	""	"1-(4-cyanophenyl)-3-[4-[4-[(4-cyanophenyl)carbamoylamino]phenoxy]phenyl]urea"	""	""	"N#Cc1ccc(cc1)NC(=O)Nc1ccc(cc1)Oc1ccc(cc1)NC(=O)Nc1ccc(cc1)C#N"	"NKTXGJQCHFJKQJ-UHFFFAOYSA-N"	"InChI=1S/C28H20N6O3/c29-17-19-1-5-21(6-2-19)31-27(35)33-23-9-13-25(14-10-23)37-26-15-11-24(12-16-26)34-28(36)32-22-7-3-20(18-30)4-8-22/h1-16H,(H2,31,33,35)(H2,32,34,36)"	"yes"	""	""
"13338"	"NT-0249"	""	"Synthetic organic"	""	""	""	""	"496703308"	"162749590"	""	""	""	""	""	""	""	"1-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)-3-[(1-methylpyrazol-4-yl)-[[(2S)-oxolan-2-yl]methyl]sulfamoyl]urea"	""	"NT0249"	"CN1C=C(C=N1)N(C[C@@H]2CCCO2)S(=O)(=O)NC(=O)NC3=C4CCCC4=CC5=C3CCC5"	"BISMWMMNUMFVKI-SFHVURJKSA-N"	"InChI=1S/C22H29N5O4S/c1-26-13-17(12-23-26)27(14-18-7-4-10-31-18)32(29,30)25-22(28)24-21-19-8-2-5-15(19)11-16-6-3-9-20(16)21/h11-13,18H,2-10,14H2,1H3,(H2,24,25,28)/t18-/m0/s1"	"yes"	""	""
"13008"	"NT-0796"	""	"Synthetic organic"	""	""	""	""	"485206129"	"152031485"	""	""	""	""	""	""	""	"propan-2-yl (2R)-2-(1,2,3,5,6,7-hexahydro-s-indacen-4-ylcarbamoyloxy)-3-pyrimidin-2-ylpropanoate"	""	"NT0796"	"C1CCC2=C(C=3CCCC3C=C12)NC(=O)O[C@@H](C(=O)OC(C)C)CC4=NC=CC=N4"	"UMUQEMHROZVOTF-LJQANCHMSA-N"	"InChI=1S/C23H27N3O4/c1-14(2)29-22(27)19(13-20-24-10-5-11-25-20)30-23(28)26-21-17-8-3-6-15(17)12-16-7-4-9-18(16)21/h5,10-12,14,19H,3-4,6-9,13H2,1-2H3,(H,26,28)/t19-/m1/s1"	"yes"	""	""
"12992"	"nurulimab"	""	"Antibody"	""	""	""	""	"485206113"	""	""	""	""	""	""	""	""	""	"nurulimab"	"BCD-145|BCD145"	""	""	""	"yes"	""	""
"12519"	"NX-2127"	""	"Synthetic organic"	""	""	""	""	"479821309"	"167282486"	""	""	""	""	""	""	""	"3-[4-[1-[[(3R)-1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]pyrrolidin-3-yl]methyl]piperidin-4-yl]anilino]-5-piperidin-1-ylpyrazine-2-carboxamide"	""	""	"NC(=O)C1=C(NC2=CC=C(C=C2)C3CCN(C[C@H]4CCN(C4)C5=CC6=C(C=C5)C(=O)N(C7CCC(=O)NC7=O)C6=O)CC3)N=C(C=N1)N8CCCCC8"	"XLWJWCMQMBVNSG-LZDHLTRGSA-N"	"InChI=1S/C39H45N9O5/c40-35(50)34-36(43-32(21-41-34)46-15-2-1-3-16-46)42-27-6-4-25(5-7-27)26-13-17-45(18-14-26)22-24-12-19-47(23-24)28-8-9-29-30(20-28)39(53)48(38(29)52)31-10-11-33(49)44-37(31)51/h4-9,20-21,24,26,31H,1-3,10-19,22-23H2,(H2,40,50)(H,42,43)(H,44,49,51)/t24-,31?/m1/s1"	"yes"	""	""
"11086"	"obatoclax"	""	"Synthetic organic"	""	""	""	""	"434122147"	"46930997"	""	""	""	""	""	""	""	""	"obatoclax"	"GX-15-070|GX15-070|obatoclax mesylate|SB16622"	"COc1c/c(=C\2/C=c3c(=N2)cccc3)/[nH]/c/1=C\c1[nH]c(cc1C)C"	"CVCLJVVBHYOXDC-LKIBBAOUSA-N"	"InChI=1S/C20H19N3O/c1-12-8-13(2)21-16(12)10-19-20(24-3)11-18(23-19)17-9-14-6-4-5-7-15(14)22-17/h4-11,21,23H,1-3H3/b18-17+,19-10-"	"yes"	""	""
"6941"	"obinutuzumab"	""	"Antibody"	"yes"	""	""	""	"178103523"	""	""	""	""	""	""	""	""	""	"obinutuzumab"	"GA-101|GA101|Gazyva&reg;"	""	""	""	"yes"	""	""
"13504"	"ocadusertib"	""	"Synthetic organic"	""	""	""	""	"500839914"	"146225852"	""	""	""	""	""	""	""	"5-benzyl-N-[(3S)-7-(3-hydroxy-3-methylbut-1-ynyl)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide"	"ocadusertib"	"compound I-30 [WO2021046407]|LY-3871801|LY3871801|R-552|R552"	"CC(C)(C#CC1=CC2=C(C=C1)OC[C@@H](C(=O)N2C)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4)O"	"SQBZJKIINNRUFC-SFHVURJKSA-N"	"InChI=1S/C25H25N5O4/c1-25(2,33)12-11-17-9-10-20-19(13-17)30(3)24(32)18(15-34-20)26-23(31)22-27-21(28-29-22)14-16-7-5-4-6-8-16/h4-10,13,18,33H,14-15H2,1-3H3,(H,26,31)(H,27,28,29)/t18-/m0/s1"	"yes"	""	""
"14050"	"ocipumaltib"	""	"Synthetic organic"	""	""	""	""	"518520677"	"151085091"	""	""	""	""	""	""	""	"1-[6-chloro-4-[(1S)-1-methoxyethyl]-1,5-naphthyridin-3-yl]-3-[6-(triazol-2-yl)-5-(trifluoromethyl)pyridin-3-yl]urea"	"ocipumaltib"	"compound A  [WO2023149450A1]|CTX-177|CTX177"	"ClC=1N=C2C(=C(C=NC2=CC1)NC(=O)NC=3C=NC(=C(C3)C(F)(F)F)N4N=CC=N4)[C@H](C)OC"	"MKYDKGUTYKFCHS-JTQLQIEISA-N"	"InChI=1S/C20H16ClF3N8O2/c1-10(34-2)16-14(9-25-13-3-4-15(21)31-17(13)16)30-19(33)29-11-7-12(20(22,23)24)18(26-8-11)32-27-5-6-28-32/h3-10H,1-2H3,(H2,29,30,33)/t10-/m0/s1"	"yes"	""	""
"9696"	"oclacitinib"	""	"Synthetic organic"	""	""	""	""	"348353655"	"44631938"	""	""	"CHEMBL2103874"	""	""	""	""	""	"oclacitinib"	"Apoquel&reg; (veterinary use)|PF-03394197"	"CNS(=O)(=O)C[C@@H]1CC[C@H](CC1)N(c1[nH]cnc2c1ccn2)C"	"HJWLJNBZVZDLAQ-HAQNSBGRSA-N"	"InChI=1S/C15H23N5O2S/c1-16-23(21,22)9-11-3-5-12(6-4-11)20(2)15-13-7-8-17-14(13)18-10-19-15/h7-8,10-12,16H,3-6,9H2,1-2H3,(H,17,18,19)/t11-,12-"	"yes"	""	""
"7580"	"ocrelizumab"	""	"Antibody"	"yes"	""	""	""	"223365915"	""	""	""	""	""	""	""	""	""	"ocrelizumab"	"2H7|Ocrevus&reg;|PRO70769|RG1594"	""	""	""	"yes"	""	""
"10406"	"OD36"	""	"Synthetic organic"	""	""	""	""	"385612168"	"135567262"	""	""	""	""	""	""	""	"4-chloro-7,10-dioxa-13,17,18,21-tetrazatetracyclo[12.5.2.12,6.017,20]docosa-1(20),2(22),3,5,14(21),15,18-heptaene"	""	""	"Clc1cc2OCCOCCNc3nc4c(c(c1)c2)cnn4cc3"	"KTSDBMVHAKWDRK-UHFFFAOYSA-N"	"InChI=1S/C16H15ClN4O2/c17-12-7-11-8-13(9-12)23-6-5-22-4-2-18-15-1-3-21-16(20-15)14(11)10-19-21/h1,3,7-10H,2,4-6H2,(H,18,20)"	"yes"	""	""
"6778"	"ofatumumab"	""	"Antibody"	"yes"	""	""	""	"178103384"	""	""	""	""	""	""	""	""	""	"ofatumumab"	"Arzerra&reg;|GSK 1841157|GSK1841157|humax-CD20|Kesimpta&reg; (subcutaneous)|OMB-157|OMB157"	""	""	""	"yes"	""	""
"13227"	"ofirnoflast"	""	"Synthetic organic"	""	""	""	""	"491300009"	"162365111"	""	""	""	""	""	""	""	"1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea"	"ofirnoflast"	"example 10 [WO2021242505]|HT-6184|HT6184"	"NC=1C2=C(N=CN1)N(C=C2C3=CC(=C(C=C3)NC(=O)NC4=NOC(=C4)C5(CC5)C(F)(F)F)F)C6CC6"	"MJUUWYZZPRAKCW-UHFFFAOYSA-N"	"InChI=1S/C23H19F4N7O2/c24-14-7-11(13-9-34(12-2-3-12)20-18(13)19(28)29-10-30-20)1-4-15(14)31-21(35)32-17-8-16(36-33-17)22(5-6-22)23(25,26)27/h1,4,7-10,12H,2-3,5-6H2,(H2,28,29,30)(H2,31,32,33,35)"	"yes"	""	""
"9729"	"olamkicept"	""	"Peptide"	""	""	""	""	"354702205"	""	""	""	""	""	""	""	""	""	"olamkicept"	"FE 999301|FE-301|FE-999301|TJ301"	""	""	""	"yes"	""	""
"9674"	"olaptesed pegol"	""	"Synthetic organic"	""	""	""	""	"348353633"	""	""	""	""	""	""	""	""	""	"olaptesed pegol"	"NOX-A12"	""	""	""	"yes"	""	""
"9596"	"oleclumab"	""	"Antibody"	""	""	""	""	"340590226"	""	""	""	""	""	""	""	""	""	"oleclumab"	"MEDI 9447|MEDI-9447"	""	""	""	"yes"	""	""
"10213"	"olinciguat"	""	"Synthetic organic"	""	""	""	""	"381744895"	"90445883"	""	""	""	""	""	""	""	"(2~{R})-3,3,3-trifluoro-2-[[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]amino]methyl]-2-hydroxypropanamide"	"olinciguat"	"IW-1701|IW1701"	"NC(=O)[C@@](C(F)(F)F)(CNc1nc(ncc1F)c1nn(c(c1)c1nocc1)Cc1ccccc1F)O"	"YWQFJNWMWZMXRW-HXUWFJFHSA-N"	"InChI=1S/C21H16F5N7O3/c22-12-4-2-1-3-11(12)9-33-16(14-5-6-36-32-14)7-15(31-33)18-28-8-13(23)17(30-18)29-10-20(35,19(27)34)21(24,25)26/h1-8,35H,9-10H2,(H2,27,34)(H,28,29,30)/t20-/m1/s1"	"yes"	""	""
"7543"	"olodaterol"	""	"Synthetic organic"	"yes"	""	""	""	"187051844"	"11504295"	""	""	"CHEMBL605846"	""	""	""	""	"6-hydroxy-8-[(1R)-1-hydroxy-2-[[1-(4-methoxyphenyl)-2-methylpropan-2-yl]amino]ethyl]-4H-1,4-benzoxazin-3-one"	"olodaterol"	"BI-1744|BI-1744-CL|Striverdi&reg;"	"COc1ccc(cc1)CC(NC[C@@H](c1cc(O)cc2c1OCC(=O)N2)O)(C)C"	"COUYJEVMBVSIHV-SFHVURJKSA-N"	"InChI=1S/C21H26N2O5/c1-21(2,10-13-4-6-15(27-3)7-5-13)22-11-18(25)16-8-14(24)9-17-20(16)28-12-19(26)23-17/h4-9,18,22,24-25H,10-12H2,1-3H3,(H,23,26)/t18-/m0/s1"	"yes"	""	""
"7249"	"olopatadine"	""	"Synthetic organic"	"yes"	""	""	""	"178103823"	"5281071"	""	""	"CHEMBL1189432"	""	""	""	""	"2-[(11Z)-11-[3-(dimethylamino)propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid"	"olopatadine"	"ALO-4943A|KW-4679|Opatanol&reg;|Patanol&reg;|Pazeo&reg;"	"CN(CC/C=C/1\c2cc(ccc2OCc2c1cccc2)CC(=O)O)C"	"JBIMVDZLSHOPLA-LSCVHKIXSA-N"	"InChI=1S/C21H23NO3/c1-22(2)11-5-8-18-17-7-4-3-6-16(17)14-25-20-10-9-15(12-19(18)20)13-21(23)24/h3-4,6-10,12H,5,11,13-14H2,1-2H3,(H,23,24)/b18-8-"	"yes"	""	""
"10630"	"olverembatinib"	""	"Synthetic organic"	"yes"	""	""	""	"404859077"	"51038269"	""	""	"CHEMBL2316582"	""	""	""	""	"4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[2-(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide"	"olverembatinib"	"compound 10a [PMID: 23301703]|GZD-824|GZD824|HQP-1351|HQP1351"	"CN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)c1ccc(c(c1)C#Cc1cnc2c(c1)cn[nH]2)C"	"TZKBVRDEOITLRB-UHFFFAOYSA-N"	"InChI=1S/C29H27F3N6O/c1-19-3-5-22(14-21(19)6-4-20-13-24-17-34-36-27(24)33-16-20)28(39)35-25-8-7-23(26(15-25)29(30,31)32)18-38-11-9-37(2)10-12-38/h3,5,7-8,13-17H,9-12,18H2,1-2H3,(H,35,39)(H,33,34,36)"	"yes"	""	""
"6890"	"omalizumab"	""	"Antibody"	"yes"	""	""	""	"178103472"	""	""	""	""	""	""	""	""	""	"omalizumab"	"IGE25|olizumab|R03DX05|RG-3648|rhumab-E25|Xolair&reg;"	""	""	""	"yes"	""	""
"7573"	"omaveloxolone"	""	"Synthetic organic"	"yes"	""	""	""	"223365909"	"71811910"	""	""	""	""	""	""	""	"N-[(4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,3,4,5,6,7,8,8a,14a,14b-decahydropicen-4a-yl]-2,2-difluoropropanamide"	"omaveloxolone"	"RTA 408|RTA-408|Skyclarys&reg;"	"N#CC1=C[C@@]2(C)[C@H](C(C1=O)(C)C)CC[C@@]1(C2=CC(=O)[C@H]2[C@@]1(C)CC[C@@]1([C@H]2CC(C)(C)CC1)NC(=O)C(F)(F)C)C"	"RJCWBNBKOKFWNY-IDPLTSGASA-N"	"InChI=1S/C33H44F2N2O3/c1-27(2)11-13-33(37-26(40)32(8,34)35)14-12-31(7)24(20(33)17-27)21(38)15-23-29(5)16-19(18-36)25(39)28(3,4)22(29)9-10-30(23,31)6/h15-16,20,22,24H,9-14,17H2,1-8H3,(H,37,40)/t20-,22-,24-,29-,30+,31+,33-/m0/s1"	"yes"	""	""
"10363"	"omilancor"	""	"Synthetic organic"	""	""	""	""	"384403643"	"121299620"	""	""	"CHEMBL4788758"	""	""	""	""	"[4-[6-(1H-benzimidazol-2-yl)pyridine-2-carbonyl]piperazin-1-yl]-[6-(1H-benzimidazol-2-yl)pyridin-2-yl]methanone"	"omilancor"	"analogue 7 [PMID: 27933891]|BT-11|BT11|Example 1 [US9556146B2]"	"O=C(c1cccc(n1)c1nc2c([nH]1)cccc2)N1CCN(CC1)C(=O)c1cccc(n1)c1nc2c([nH]1)cccc2"	"MVHWZNBAQIGPOQ-UHFFFAOYSA-N"	"InChI=1S/C30H24N8O2/c39-29(25-13-5-11-23(31-25)27-33-19-7-1-2-8-20(19)34-27)37-15-17-38(18-16-37)30(40)26-14-6-12-24(32-26)28-35-21-9-3-4-10-22(21)36-28/h1-14H,15-18H2,(H,33,34)(H,35,36)"	"yes"	""	""
"8974"	"omipalisib"	""	"Synthetic organic"	""	""	""	""	"310264754"	"25167777"	""	""	"CHEMBL1236962"	""	""	""	""	"2,4-difluoro-N-[2-methoxy-5-(4-pyridazin-4-ylquinolin-6-yl)pyridin-3-yl]benzenesulfonamide"	"omipalisib"	"GSK 2126458|GSK-2126458|GSK2126458"	"COc1ncc(cc1NS(=O)(=O)c1ccc(cc1F)F)c1ccc2c(c1)c(ccn2)c1ccnnc1"	"CGBJSGAELGCMKE-UHFFFAOYSA-N"	"InChI=1S/C25H17F2N5O3S/c1-35-25-23(32-36(33,34)24-5-3-18(26)12-21(24)27)11-17(13-29-25)15-2-4-22-20(10-15)19(7-8-28-22)16-6-9-30-31-14-16/h2-14,32H,1H3"	"yes"	""	""
"9757"	"onfekafusp alfa"	""	"Antibody"	""	""	""	""	"354702230"	""	""	""	""	""	""	""	""	""	"onfekafusp alfa"	"Daramun (bifikafusp alfa and onfekafusp alfa)|Fibronum|L19TNF-alpha|Nidlegy (bifikafusp alfa and onfekafusp alfa)"	""	""	""	"yes"	""	""
"1942"	"ONO-AE3-208"	""	"Synthetic organic"	""	""	""	""	"135650770"	"10111831"	""	""	""	""	""	""	""	"4-[4-cyano-2-[2-(4-fluoronaphthalen-1-yl)propanoylamino]phenyl]butanoic acid"	""	"ONO AE3 208"	"N#Cc1ccc(c(c1)NC(=O)C(c1ccc(c2c1cccc2)F)C)CCCC(=O)O"	"MTDIMKNAJUQTIO-UHFFFAOYSA-N"	"InChI=1S/C24H21FN2O3/c1-15(18-11-12-21(25)20-7-3-2-6-19(18)20)24(30)27-22-13-16(14-26)9-10-17(22)5-4-8-23(28)29/h2-3,6-7,9-13,15H,4-5,8H2,1H3,(H,27,30)(H,28,29)"	"yes"	""	""
"9340"	"ontamalimab"	""	"Antibody"	""	""	""	""	"328083443"	""	""	""	""	""	""	""	""	""	"ontamalimab"	"PF-00547659|PF-547659|SHP647"	""	""	""	"yes"	""	""
"9031"	"ONX-0914"	""	"Synthetic organic"	""	""	""	""	"315661116"	"23642227"	""	""	""	""	""	""	""	"(2S)-3-(4-methoxyphenyl)-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide"	""	"PR-957"	"COc1ccc(cc1)C[C@@H](C(=O)N[C@H](C(=O)[C@@]1(C)CO1)Cc1ccccc1)NC(=O)[C@@H](NC(=O)CN1CCOCC1)C"	"WQAVPPWWLLVGFK-VTNASVEKSA-N"	"InChI=1S/C31H40N4O7/c1-21(32-27(36)19-35-13-15-41-16-14-35)29(38)34-26(18-23-9-11-24(40-3)12-10-23)30(39)33-25(28(37)31(2)20-42-31)17-22-7-5-4-6-8-22/h4-12,21,25-26H,13-20H2,1-3H3,(H,32,36)(H,33,39)(H,34,38)/t21-,25-,26-,31+/m0/s1"	"yes"	""	""
"6971"	"oprelvekin"	""	"Peptide"	"yes"	""	""	""	"178103550"	""	""	""	"CHEMBL1201573"	""	""	""	""	""	"oprelvekin"	"Neumega&reg;"	""	""	""	"yes"	""	""
"13046"	"ordesekimab"	""	"Antibody"	""	""	""	""	"491299828"	""	""	""	""	""	""	""	""	""	"ordesekimab"	"AMG-714|AMG714|MAb146B7|PRV-015"	""	""	""	"yes"	""	""
"10629"	"orelabrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"404859076"	"91667513"	""	""	""	""	""	""	""	""	"orelabrutinib"	"example 3 [WO2015048662A2]|ICP-022|ICP022"	"C=CC(=O)N1CCC(CC1)c1ccc(c(n1)c1ccc(cc1)Oc1ccccc1)C(=O)N"	"MZPVEMOYADUARK-UHFFFAOYSA-N"	"InChI=1S/C26H25N3O3/c1-2-24(30)29-16-14-18(15-17-29)23-13-12-22(26(27)31)25(28-23)19-8-10-21(11-9-19)32-20-6-4-3-5-7-20/h2-13,18H,1,14-17H2,(H2,27,31)"	"yes"	""	""
"11310"	"ORG 214007-0"	""	"Synthetic organic"	""	""	""	""	"434321745"	"154659439"	""	""	""	""	""	""	""	""	""	"[(-)-N-(2S,10S,14bS)]-N-(8-cyano-1,2,3,4,10,14b-hexahydro-10-methyl dibenzo[c,f]pyrido[1,2-a]azepin-2-yl)-4-methyl-1,2,3-thiadiazole-5-carboxamide]]|ORG214007-0"	"N#Cc1ccc2c(c1)[C@@H](C)c1ccccc1[C@H]1N2CC[C@@H](C1)NC(=O)c1snnc1C"	"BUWMTEGCNUYHSZ-JKXTWKSPSA-N"	"InChI=1S/C24H23N5OS/c1-14-18-5-3-4-6-19(18)22-12-17(26-24(30)23-15(2)27-28-31-23)9-10-29(22)21-8-7-16(13-25)11-20(14)21/h3-8,11,14,17,22H,9-10,12H2,1-2H3,(H,26,30)/t14-,17-,22-/m0/s1"	"yes"	""	""
"9985"	"Orita-13"	""	"Synthetic organic"	""	""	""	""	"374883872"	"5284648"	""	""	"CHEMBL13486"	""	""	""	""	"3-(3,4-dihydroxyphenyl)-7-hydroxychromen-4-one"	""	"compound 13 [PMID: 11170644]"	"Oc1ccc2c(c1)occ(c2=O)c1ccc(c(c1)O)O"	"DDKGKOOLFLYZDL-UHFFFAOYSA-N"	"InChI=1S/C15H10O5/c16-9-2-3-10-14(6-9)20-7-11(15(10)19)8-1-4-12(17)13(18)5-8/h1-7,16-18H"	"yes"	""	""
"13522"	"oroxylin A"	""	"Natural product"	""	""	""	""	"500839932"	"5320315"	""	""	"CHEMBL183513"	""	""	""	""	"5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one"	""	""	"COC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=CC=C3)O"	"LKOJGSWUMISDOF-UHFFFAOYSA-N"	"InChI=1S/C16H12O5/c1-20-16-11(18)8-13-14(15(16)19)10(17)7-12(21-13)9-5-3-2-4-6-9/h2-8,18-19H,1H3"	"yes"	""	""
"10302"	"osthole"	""	"Natural product"	""	""	""	""	"381744983"	"10228"	""	""	"CHEMBL52229"	""	""	""	""	"7-methoxy-8-(3-methylbut-2-enyl)chromen-2-one"	""	"7-Methoxy-8-isopentenylcoumarin|osthol"	"COc1ccc2c(c1CC=C(C)C)oc(=O)cc2"	"MBRLOUHOWLUMFF-UHFFFAOYSA-N"	"InChI=1S/C15H16O3/c1-10(2)4-7-12-13(17-3)8-5-11-6-9-14(16)18-15(11)12/h4-6,8-9H,7H2,1-3H3"	"yes"	""	""
"9534"	"otenaproxesul"	""	"Synthetic organic"	""	""	""	""	"336446920"	"72941967"	""	""	""	""	""	""	""	""	"otenaproxesul"	"ATB 346|ATB-346|ATB-346, (S)-|ATB346"	"COc1ccc2c(c1)ccc(c2)[C@@H](C(=O)Oc1ccc(cc1)C(=S)N)C"	"YCNMAPLPQYQJFC-ZDUSSCGKSA-N"	"InChI=1S/C21H19NO3S/c1-13(21(23)25-18-8-5-14(6-9-18)20(22)26)15-3-4-17-12-19(24-2)10-7-16(17)11-15/h3-13H,1-2H3,(H2,22,26)/t13-/m0/s1"	"yes"	""	""
"11132"	"otilimab"	""	"Antibody"	""	""	""	""	"434122192"	""	""	""	""	""	""	""	""	""	"otilimab"	"GSK-3196165|GSK3196165|MOR-103|MOR103"	""	""	""	"yes"	""	""
"9951"	"otlertuzumab"	""	"Antibody"	""	""	""	""	"374883838"	""	""	""	"CHEMBL3039539"	""	""	""	""	""	"otlertuzumab"	"CD37-SMIP|TRU-016|TRU016"	""	""	""	"yes"	""	""
"5076"	"OX-40 ligand"	"Human"	"Peptide"	""	""	""	""	"178101769"	""	"P23510"	"ENSG00000117586"	""	""	""	""	""	""	""	"glycoprotein Gp34|TXGP-1"	""	""	""	"yes"	""	""
"7252"	"oxaprozin"	""	"Synthetic organic"	"yes"	""	""	""	"178103826"	"4614"	""	""	"CHEMBL1071"	""	""	""	""	"3-(diphenyl-1,3-oxazol-2-yl)propanoic acid"	"oxaprozin"	"Daypro&reg;|WY-21743"	"OC(=O)CCc1nc(c(o1)c1ccccc1)c1ccccc1"	"OFPXSFXSNFPTHF-UHFFFAOYSA-N"	"InChI=1S/C18H15NO3/c20-16(21)12-11-15-19-17(13-7-3-1-4-8-13)18(22-15)14-9-5-2-6-10-14/h1-10H,11-12H2,(H,20,21)"	"yes"	""	""
"9866"	"ozagrel"	""	"Synthetic organic"	"yes"	""	""	""	"363894160"	"5282440"	""	""	"CHEMBL11662"	""	""	""	""	"3-[4-(imidazol-1-ylmethyl)phenyl]prop-2-enoic acid"	"ozagrel"	"Cataclot&reg;|KCT-0809|OKY-046|Pulmoza&reg;"	"OC(=O)/C=C/c1ccc(cc1)Cn1ccnc1"	"SHZKQBHERIJWAO-AATRIKPKSA-N"	"InChI=1S/C13H12N2O2/c16-13(17)6-5-11-1-3-12(4-2-11)9-15-8-7-14-10-15/h1-8,10H,9H2,(H,16,17)/b6-5+"	"yes"	""	""
"8709"	"ozanimod"	""	"Synthetic organic"	"yes"	""	""	""	"252827367"	"52938427"	""	""	""	""	""	""	""	"5-[3-[(1S)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile"	"ozanimod"	"RPC-1063|RPC1063|Zeposia&reg;"	"OCCN[C@H]1CCc2c1cccc2c1noc(n1)c1ccc(c(c1)C#N)OC(C)C"	"XRVDGNKRPOAQTN-FQEVSTJZSA-N"	"InChI=1S/C23H24N4O3/c1-14(2)29-21-9-6-15(12-16(21)13-24)23-26-22(27-30-23)19-5-3-4-18-17(19)7-8-20(18)25-10-11-28/h3-6,9,12,14,20,25,28H,7-8,10-11H2,1-2H3/t20-/m0/s1"	"yes"	""	""
"9638"	"ozoralizumab"	""	"Antibody"	""	""	""	""	"340590268"	""	""	""	""	""	""	""	""	""	"ozoralizumab"	"ATN-103|PF-5230896"	""	""	""	"yes"	""	""
"14334"	"ozureprubart"	""	"Antibody"	""	""	""	""	"523352126"	""	""	""	""	""	""	""	""	""	"ozureprubart"	"JYB1904|RPT-904|RPT904"	""	""	""	"yes"	""	""
"13422"	"P2Y<sub>14</sub>R antagonist I-17"	""	"Synthetic organic"	""	""	""	""	"496703392"	"166194091"	""	""	""	""	""	""	""	"N-(3H-benzimidazol-5-yl)-2-(4-bromophenoxy)acetamide"	""	"compound I-17 [PMID: 38874515]"	"C1=CC(=CC=C1OCC(=O)NC2=CC3=C(C=C2)N=CN3)Br"	"OMPWLXOPMAMOCA-UHFFFAOYSA-N"	"InChI=1S/C15H12BrN3O2/c16-10-1-4-12(5-2-10)21-8-15(20)19-11-3-6-13-14(7-11)18-9-17-13/h1-7,9H,8H2,(H,17,18)(H,19,20)"	"yes"	""	""
"8070"	"P505-15"	""	"Synthetic organic"	""	""	""	""	"249565750"	"44462758"	""	""	"CHEMBL2177736"	""	""	""	""	"2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[3-(triazol-2-yl)anilino]pyrimidine-5-carboxamide"	""	"BIIB057|PRT-062607|PRT062607"	"N[C@H]1CCCC[C@H]1Nc1ncc(c(n1)Nc1cccc(c1)n1nccn1)C(=O)N"	"TXGKRVFSSHPBAJ-JKSUJKDBSA-N"	"InChI=1S/C19H23N9O/c20-15-6-1-2-7-16(15)26-19-22-11-14(17(21)29)18(27-19)25-12-4-3-5-13(10-12)28-23-8-9-24-28/h3-5,8-11,15-16H,1-2,6-7,20H2,(H2,21,29)(H2,22,25,26,27)/t15-,16+/m0/s1"	"yes"	""	""
"14206"	"pacibekitug"	""	"Antibody"	""	""	""	""	"518520833"	""	""	""	""	""	""	""	""	""	"pacibekitug"	"PF 4236921|PF-4236921|PF04236921|TOUR-006|TOUR006"	""	""	""	"yes"	""	""
"1831"	"PAF"	""	"Metabolite"	""	""	""	""	"135651534"	"108156"	""	""	"CHEMBL1235246"	""	""	""	""	"[(2R)-2-acetyloxy-3-hexadecoxypropyl] 2-trimethylazaniumylethyl phosphate"	""	"PAF (C16)|PAF C-16|platelet activating factor"	"CCCCCCCCCCCCCCCCOC[C@@H](OC(=O)C)COP(=O)(OCC[N+](C)(C)C)[O-]"	"HVAUUPRFYPCOCA-AREMUKBSSA-N"	"InChI=1S/C26H54NO7P/c1-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-31-23-26(34-25(2)28)24-33-35(29,30)32-22-20-27(3,4)5/h26H,6-24H2,1-5H3/t26-/m1/s1"	"yes"	""	""
"8560"	"Pam2CSK4"	""	"Peptide"	""	""	""	""	"252166761"	"9989023"	""	""	""	""	""	""	""	"(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2R)-2-amino-3-[2,3-di(hexadecanoyloxy)propylsulfanyl]propanoyl]amino]-3-hydroxypropanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoyl]amino]hexanoic acid"	""	""	"CCCCCCCCCCCCCCCC(=O)OC(COC(=O)CCCCCCCCCCCCCCC)CSC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CCCCN)CCCCN)CCCCN)CCCCN)CO)N"	"LJUIOEFZFQRWJG-KKIBDXJDSA-N"	"InChI=1S/C65H126N10O12S/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-41-58(77)86-48-51(87-59(78)42-28-26-24-22-20-18-16-14-12-10-8-6-4-2)49-88-50-52(70)60(79)75-57(47-76)64(83)73-54(38-30-34-44-67)62(81)71-53(37-29-33-43-66)61(80)72-55(39-31-35-45-68)63(82)74-56(65(84)85)40-32-36-46-69/h51-57,76H,3-50,66-70H2,1-2H3,(H,71,81)(H,72,80)(H,73,83)(H,74,82)(H,75,79)(H,84,85)/t51?,52-,53-,54-,55-,56-,57-/m0/s1"	"yes"	""	""
"8558"	"Pam3CSK4"	""	"Peptide"	""	""	""	""	"252166759"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9915"	"pamapimod"	""	"Synthetic organic"	""	""	""	""	"363894209"	"16220188"	""	""	"CHEMBL1090089"	""	""	""	""	"6-(2,4-difluorophenoxy)-2-(1,5-dihydroxypentan-3-ylamino)-8-methylpyrido[2,3-d]pyrimidin-7-one"	"pamapimod"	"compound 2b [PMID: 21375264]|Ro 4402257|Ro-4402257|Ro4402257"	"OCCC(Nc1ncc2c(n1)n(C)c(=O)c(c2)Oc1ccc(cc1F)F)CCO"	"JYYLVUFNAHSSFE-UHFFFAOYSA-N"	"InChI=1S/C19H20F2N4O4/c1-25-17-11(10-22-19(24-17)23-13(4-6-26)5-7-27)8-16(18(25)28)29-15-3-2-12(20)9-14(15)21/h2-3,8-10,13,26-27H,4-7H2,1H3,(H,22,23,24)"	"yes"	""	""
"2895"	"parecoxib"	""	"Synthetic organic"	"yes"	""	""	""	"178100244"	"119828"	""	""	"CHEMBL1206690"	""	""	""	""	"N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonylpropanamide"	"parecoxib"	"Dynastat&reg;|SC-69124"	"CCC(=O)NS(=O)(=O)c1ccc(cc1)c1c(C)onc1c1ccccc1"	"TZRHLKRLEZJVIJ-UHFFFAOYSA-N"	"InChI=1S/C19H18N2O4S/c1-3-17(22)21-26(23,24)16-11-9-14(10-12-16)18-13(2)25-20-19(18)15-7-5-4-6-8-15/h4-12H,3H2,1-2H3,(H,21,22)"	"yes"	""	""
"13714"	"paridiprubart"	""	"Antibody"	""	""	""	""	"507750348"	""	""	""	""	""	""	""	""	""	"paridiprubart"	"EB05|NI 0101|NI-0101"	""	""	""	"yes"	""	""
"10098"	"parsaclisib"	""	"Synthetic organic"	""	""	""	""	"381118808"	"89420683"	""	""	""	""	""	""	""	""	"parsaclisib"	"compound 20 [PMID: 31749910]|IBI376|INCB-050465"	"CCOc1c(C2CNC(=O)C2)c(F)c(cc1[C@@H](n1nc(c2c1ncnc2N)C)C)Cl"	"ZQPDJCIXJHUERQ-VUWPPUDQSA-N"	"InChI=1S/C20H22ClFN6O2/c1-4-30-18-12(6-13(21)17(22)16(18)11-5-14(29)24-7-11)10(3)28-20-15(9(2)27-28)19(23)25-8-26-20/h6,8,10-11H,4-5,7H2,1-3H3,(H,24,29)(H2,23,25,26)/t10-,11?/m0/s1"	"yes"	""	""
"14415"	"parunoflast"	""	"Synthetic organic"	""	""	""	""	"523352207"	"169066851"	""	""	""	""	""	""	""	"2-[6-[(R)-hydroxy-[(3R)-1-methylpiperidin-3-yl]methyl]-4-methylpyridazin-3-yl]-5-(trifluoromethyl)phenol"	"parunoflast"	"Compound 17B [WO2023178099]"	"O[C@@H](C1=CC(=C(N=N1)C2=C(C=C(C=C2)C(F)(F)F)O)C)[C@H]3CN(CCC3)C"	"RWDYJVRIDGIICC-KZULUSFZSA-N"	"InChI=1S/C19H22F3N3O2/c1-11-8-15(18(27)12-4-3-7-25(2)10-12)23-24-17(11)14-6-5-13(9-16(14)26)19(20,21)22/h5-6,8-9,12,18,26-27H,3-4,7,10H2,1-2H3/t12-,18-/m1/s1"	"yes"	""	""
"7786"	"pascolizumab"	""	"Antibody"	""	""	""	""	"223366118"	""	""	""	""	""	""	""	""	""	"pascolizumab"	"SB-240683"	""	""	""	"yes"	""	""
"9854"	"pateclizumab"	""	"Antibody"	""	""	""	""	"363894148"	""	""	""	""	""	""	""	""	""	"pateclizumab"	"MLTA3698A|PRO283698|RG7416"	""	""	""	"yes"	""	""
"14121"	"patritumab deruxtecan"	""	"Antibody"	""	""	""	""	"518520748"	""	""	""	""	""	""	""	""	""	"patritumab deruxtecan"	"HER3-DXd|MK-1022|U3-1402"	""	""	""	"yes"	""	""
"10193"	"PBF-509"	""	"Synthetic organic"	""	""	""	""	"381118903"	"53466958"	""	""	"CHEMBL3638684"	""	""	""	""	"5-bromo-2,6-di(pyrazol-1-yl)pyrimidin-4-amine"	""	"PBF509"	"Nc1nc(nc(c1Br)n1cccn1)n1cccn1"	"ATFXVNUWQOXRRU-UHFFFAOYSA-N"	"InChI=1S/C10H8BrN7/c11-7-8(12)15-10(18-6-2-4-14-18)16-9(7)17-5-1-3-13-17/h1-6H,(H2,12,15,16)"	"yes"	""	""
"9755"	"PBT-3"	""	"Synthetic organic"	""	""	""	""	"354702228"	"10341876"	""	""	""	""	""	""	""	"methyl (5Z,8Z,10S,14Z)-11,12-dicyclopropyl-10-hydroxyicosa-5,8,14-trienoate"	""	""	"CCCCC/C=C\CC(C(C1CC1)[C@H](/C=C\C/C=C\CCCC(=O)OC)O)C1CC1"	"ODNVBPFEZJHAAU-OBNWJGEWSA-N"	"InChI=1S/C27H44O3/c1-3-4-5-6-9-12-15-24(22-18-19-22)27(23-20-21-23)25(28)16-13-10-7-8-11-14-17-26(29)30-2/h7-9,12-13,16,22-25,27-28H,3-6,10-11,14-15,17-21H2,1-2H3/b8-7-,12-9-,16-13-/t24?,25-,27?/m0/s1"	"yes"	""	""
"6080"	"PCA 4248"	""	"Synthetic organic"	""	""	""	""	"178102701"	"4698"	""	""	"CHEMBL1395565"	""	""	""	""	"O5-methyl O3-(2-phenylsulfanylethyl) 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate"	""	"PCA-4248|PTEMC"	"COC(=O)C1=C(C)NC(=C(C1C)C(=O)OCCSc1ccccc1)C"	"DHCNAWNKZMNTIS-UHFFFAOYSA-N"	"InChI=1S/C19H23NO4S/c1-12-16(18(21)23-4)13(2)20-14(3)17(12)19(22)24-10-11-25-15-8-6-5-7-9-15/h5-9,12,20H,10-11H2,1-4H3"	"yes"	""	""
"9938"	"pCXCL8-1<sub>aa</sub>"	""	"Peptide"	""	""	""	""	"363894232"	"134611883"	""	""	""	""	""	""	""	""	""	""	"NCCCC[C@@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)CO)CC(=O)N)CCC(=O)O)C)CCCN=C(N)N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCC(=O)O)N)CCCCN)Cc1ccccc1)CC(C)C"	"WAKZDRBORDWUSJ-NXCVNOGKSA-N"	"InChI=1S/C53H88N16O17/c1-28(2)24-36(66-50(83)37(25-30-12-5-4-6-13-30)67-47(80)32(14-7-9-21-54)63-44(77)31(56)17-19-41(72)73)49(82)65-33(15-8-10-22-55)46(79)64-34(16-11-23-60-53(58)59)45(78)61-29(3)43(76)62-35(18-20-42(74)75)48(81)68-38(26-40(57)71)51(84)69-39(27-70)52(85)86/h4-6,12-13,28-29,31-39,70H,7-11,14-27,54-56H2,1-3H3,(H2,57,71)(H,61,78)(H,62,76)(H,63,77)(H,64,79)(H,65,82)(H,66,83)(H,67,80)(H,68,81)(H,69,84)(H,72,73)(H,74,75)(H,85,86)(H4,58,59,60)/t29-,31-,32-,33-,34-,35-,36-,37-,38-,39-/m0/s1"	"yes"	""	""
"10400"	"PDE4 inhibitor 16"	""	"Synthetic organic"	""	""	""	""	"384403679"	"138393292"	""	""	""	""	""	""	""	"(S)-6,7-Dimethoxy-1-(2-(6-methyl-1H-indol-3-yl)ethyl)-3,4-dihydroisoquinoline-2(1H)-carbaldehyde"	""	""	"O=CN1CCc2c([C@@H]1CCc1c[nH]c3c1ccc(c3)C)cc(c(c2)OC)OC"	"OIDQRHGTWLIKKZ-NRFANRHFSA-N"	"InChI=1S/C23H26N2O3/c1-15-4-6-18-17(13-24-20(18)10-15)5-7-21-19-12-23(28-3)22(27-2)11-16(19)8-9-25(21)14-26/h4,6,10-14,21,24H,5,7-9H2,1-3H3/t21-/m0/s1"	"yes"	""	""
"9782"	"pecazine"	""	"Synthetic organic"	"yes"	"yes"	""	""	"354702255"	"6075"	""	""	"CHEMBL395110"	""	""	""	""	"10-[(1-methylpiperidin-3-yl)methyl]phenothiazine"	"pecazine"	"mepazine|nothiazine|Pacatal&reg;"	"CN1CCCC(C1)CN1c2ccccc2Sc2c1cccc2"	"CBHCDHNUZWWAPP-UHFFFAOYSA-N"	"InChI=1S/C19H22N2S/c1-20-12-6-7-15(13-20)14-21-16-8-2-4-10-18(16)22-19-11-5-3-9-17(19)21/h2-5,8-11,15H,6-7,12-14H2,1H3"	"yes"	""	""
"8315"	"peficitinib"	""	"Synthetic organic"	"yes"	""	""	""	"252166527"	"57928403"	""	""	"CHEMBL3137308"	""	""	""	""	"4-[[(1R,3S)-5-hydroxy-2-adamantyl]amino]-1H-pyrrolo[2,3-b]pyridine-5-carboxamide"	"peficitinib"	"ASP015K|JNJ-54781532"	"NC(=O)c1cnc2c(c1NC1[C@@H]3CC4C[C@H]1CC(C3)(C4)O)cc[nH]2"	"DREIJXJRTLTGJC-JQCLMNFQSA-N"	"InChI=1S/C18H22N4O2/c19-16(23)13-8-21-17-12(1-2-20-17)15(13)22-14-10-3-9-4-11(14)7-18(24,5-9)6-10/h1-2,8-11,14,24H,3-7H2,(H2,19,23)(H2,20,21,22)/t9?,10-,11+,14?,18?"	"yes"	""	""
"13826"	"pegcetacoplan"	""	"Peptide"	"yes"	""	""	""	"507750459"	""	""	""	""	""	""	""	""	""	"pegcetacoplan"	"APL-2|Empaveli&reg;"	""	""	""	"yes"	""	""
"7462"	"peginterferon alfa-2b"	""	"Peptide"	"yes"	""	""	""	"187051765"	""	""	""	"CHEMBL1201561"	""	""	""	""	""	"peginterferon alfa-2b"	"PegIntron&reg;|Sylatron&reg;"	""	""	""	"yes"	""	""
"7637"	"peginterferon beta-1a"	""	"Peptide"	"yes"	""	""	""	"223365972"	""	""	""	""	""	""	""	""	""	"peginterferon beta-1a"	"interferon beta 1-alpha|PEG-INF-&beta;-1a|Plegridy&reg;"	""	""	""	"yes"	""	""
"14362"	"pelerasertib"	""	"Synthetic organic"	""	""	""	""	"523352154"	"165385717"	""	""	"CHEMBL6043794"	""	""	""	""	"4-[[2-[4-[(2S,6R)-2,6-dimethylmorpholin-4-yl]anilino]-5-fluoropyrimidin-4-yl]oxymethyl]cyclohexan-1-ol"	"pelerasertib"	"example 124 [US11578061B2]"	"C[C@@H]1CN(C[C@@H](O1)C)C2=CC=C(C=C2)NC3=NC=C(C(=N3)OCC4CCC(CC4)O)F"	"FXFDJIOOCZGIJY-HLVUACMISA-N"	"InChI=1S/C23H31FN4O3/c1-15-12-28(13-16(2)31-15)19-7-5-18(6-8-19)26-23-25-11-21(24)22(27-23)30-14-17-3-9-20(29)10-4-17/h5-8,11,15-17,20,29H,3-4,9-10,12-14H2,1-2H3,(H,25,26,27)/t15-,16+,17?,20?"	"yes"	""	""
"9876"	"pelubiprofen"	""	"Synthetic organic"	""	""	""	""	"363894170"	"5282203"	""	""	"CHEMBL69308"	""	""	""	""	"2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid"	"pelubiprofen"	"compound 13b [PMID: 6607354]|CS-670|DW-330SR|DW330SR|RS-2131"	"OC(=O)C(c1ccc(cc1)/C=C/1\CCCCC1=O)C"	"AUZUGWXLBGZUPP-GXDHUFHOSA-N"	"InChI=1S/C16H18O3/c1-11(16(18)19)13-8-6-12(7-9-13)10-14-4-2-3-5-15(14)17/h6-11H,2-5H2,1H3,(H,18,19)/b14-10+"	"yes"	""	""
"7499"	"pembrolizumab"	""	"Antibody"	"yes"	""	""	""	"187051801"	""	""	""	""	""	""	""	""	""	"pembrolizumab"	"Keytruda Qlex&reg; (pembrolizumab + berahyaluronidase alfa-pmph; for subcutaneous injection)|Keytruda&reg;|lambrolizumab|MK-3475"	""	""	""	"yes"	""	""
"7264"	"penicillamine"	""	"Synthetic organic"	"yes"	""	""	""	"178103838"	"5852"	""	""	"CHEMBL1430"	""	""	""	""	"(2S)-2-amino-3-methyl-3-sulfanylbutanoic acid"	"penicillamine"	"Cuprimine&reg;"	"N[C@H](C(S)(C)C)C(=O)O"	"VVNCNSJFMMFHPL-VKHMYHEASA-N"	"InChI=1S/C5H11NO2S/c1-5(2,9)3(6)4(7)8/h3,9H,6H2,1-2H3,(H,7,8)/t3-/m0/s1"	"yes"	""	""
"12347"	"penpulimab"	""	"Antibody"	"yes"	""	""	""	"479821138"	""	""	""	""	""	""	""	""	""	"penpulimab"	"AK-105|AK105|Aniko&reg;|penpulimab-kcqx"	""	""	""	"yes"	""	""
"10594"	"peptide 1 [PMID: 31774287]"	""	"Synthetic organic"	""	""	""	""	"404859041"	"138744511"	""	""	""	""	""	""	""	"(4R,7S,10S,13R,16S)-1-[[(2S)-2-aminopropanoyl]amino]-13-benzyl-4,10-bis(1H-indol-3-ylmethyl)-7-methyl-2,5,8,11,14-pentaoxo-21-prop-2-enyl-1,3,6,9,12,15,21-heptazacyclopentacos-23-yne-16-carboxamide"	""	""	"C=CCN1CCCC[C@H](NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)N(CC#CC1)NC(=O)[C@@H](N)C)Cc1c[nH]c2c1cccc2)C)Cc1c[nH]c2c1cccc2)C(=O)N"	"OBMZMSLWNNWEJA-XNCRXQDQSA-N"	"InChI=1S/C51H62N12O7/c1-4-23-62-24-13-12-22-41(45(53)64)57-49(68)42(27-34-16-6-5-7-17-34)59-50(69)43(28-35-30-54-39-20-10-8-18-37(35)39)58-47(66)33(3)56-48(67)44(29-36-31-55-40-21-11-9-19-38(36)40)60-51(70)63(26-15-14-25-62)61-46(65)32(2)52/h4-11,16-21,30-33,41-44,54-55H,1,12-13,22-29,52H2,2-3H3,(H2,53,64)(H,56,67)(H,57,68)(H,58,66)(H,59,69)(H,60,70)(H,61,65)/t32-,33-,41-,42+,43-,44+/m0/s1"	"yes"	""	""
"9253"	"peptide 30 [PMID: 27019010]"	""	"Peptide"	""	""	""	""	"315661328"	"11750118"	""	""	""	""	""	""	""	"methyl (2S)-2-[[(2S)-2-[[2-[(2-aminoacetyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoate"	""	""	"NCC(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)OC)CC(C)C)Cc1ccccc1"	"CSHFHJNMIMPJST-HOTGVXAUSA-N"	"InChI=1S/C20H30N4O5/c1-13(2)9-16(20(28)29-3)24-19(27)15(10-14-7-5-4-6-8-14)23-18(26)12-22-17(25)11-21/h4-8,13,15-16H,9-12,21H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)/t15-,16-/m0/s1"	"yes"	""	""
"9220"	"peptide Cp40 [PMID: 25982307]"	""	"Peptide"	""	""	""	""	"315661296"	""	""	""	""	""	""	""	""	""	""	"peptide 14"	""	""	""	"yes"	""	""
"12103"	"perenostobart"	""	"Antibody"	""	""	""	""	"472319225"	""	""	""	""	""	""	""	""	""	"perenostobart"	"SRF-617|SRF617"	""	""	""	"yes"	""	""
"9855"	"petesicatib"	""	"Synthetic organic"	""	""	""	""	"363894149"	"59543597"	""	""	""	""	""	""	""	"(2S,4R)-N-(1-cyanocyclopropyl)-4-[4-(1-methylpyrazol-4-yl)-2-(trifluoromethyl)phenyl]sulfonyl-1-[1-(trifluoromethyl)cyclopropanecarbonyl]pyrrolidine-2-carboxamide"	"petesicatib"	"RG-7625|RG7625|RO-5459072"	"N#CC1(CC1)NC(=O)[C@@H]1C[C@H](CN1C(=O)C1(CC1)C(F)(F)F)S(=O)(=O)c1ccc(cc1C(F)(F)F)c1cnn(c1)C"	"KXAAIORSMACJSI-AEFFLSMTSA-N"	"InChI=1S/C25H23F6N5O4S/c1-35-11-15(10-33-35)14-2-3-19(17(8-14)24(26,27)28)41(39,40)16-9-18(20(37)34-22(13-32)4-5-22)36(12-16)21(38)23(6-7-23)25(29,30)31/h2-3,8,10-11,16,18H,4-7,9,12H2,1H3,(H,34,37)/t16-,18+/m1/s1"	"yes"	""	""
"8179"	"PF-03715455"	""	"Synthetic organic"	""	""	""	""	"249565859"	"11714580"	""	""	"CHEMBL1938400"	""	""	""	""	"1-[5-tert-butyl-2-(3-chloro-4-hydroxyphenyl)pyrazol-3-yl]-3-[[2-[[3-[2-(2-hydroxyethylsulfanyl)phenyl]-[1,2,4]triazolo[3,4-f]pyridin-6-yl]sulfanyl]phenyl]methyl]urea"	""	""	"OCCSc1ccccc1c1nnc2n1cc(cc2)Sc1ccccc1CNC(=O)Nc1cc(nn1c1ccc(c(c1)Cl)O)C(C)(C)C"	"VGEXRDWWPSGZDH-UHFFFAOYSA-N"	"InChI=1S/C35H34ClN7O3S2/c1-35(2,3)30-19-32(43(41-30)23-12-14-27(45)26(36)18-23)38-34(46)37-20-22-8-4-6-10-28(22)48-24-13-15-31-39-40-33(42(31)21-24)25-9-5-7-11-29(25)47-17-16-44/h4-15,18-19,21,44-45H,16-17,20H2,1-3H3,(H2,37,38,46)"	"yes"	""	""
"9054"	"PF-04191834"	""	"Synthetic organic"	""	""	""	""	"315661139"	"24986635"	""	""	""	""	""	""	""	"4-[3-[4-(2-methylpyrazol-3-yl)phenyl]sulfanylphenyl]oxane-4-carboxamide"	""	"PF 4191834|PF-4191834"	"Cn1nccc1c1ccc(cc1)Sc1cccc(c1)C1(CCOCC1)C(=O)N"	"DVNQWYLVSNPCJZ-UHFFFAOYSA-N"	"InChI=1S/C22H23N3O2S/c1-25-20(9-12-24-25)16-5-7-18(8-6-16)28-19-4-2-3-17(15-19)22(21(23)26)10-13-27-14-11-22/h2-9,12,15H,10-11,13-14H2,1H3,(H2,23,26)"	"yes"	""	""
"5817"	"PF-04418948"	""	"Synthetic organic"	""	""	""	""	"178102442"	"25114442"	""	""	"CHEMBL3286797"	""	""	""	""	"1-(4-fluorobenzoyl)-3-[(6-methoxynaphthalen-2-yl)oxymethyl]azetidine-3-carboxylic acid"	""	"PF 04418948|PF04418948"	"COc1ccc2c(c1)ccc(c2)OCC1(CN(C1)C(=O)c1ccc(cc1)F)C(=O)O"	"LWJGMYMNSNVCEM-UHFFFAOYSA-N"	"InChI=1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28)"	"yes"	""	""
"9979"	"PF-04634817"	""	"Synthetic organic"	""	""	""	""	"374883866"	"46198579"	""	""	""	""	""	""	""	"[(1S,3R)-3-[[(3S,4S)-3-methoxyoxan-4-yl]amino]-1-propan-2-ylcyclopentyl]-[(1S,4S)-5-[6-(trifluoromethyl)pyrimidin-4-yl]-2,5-diazabicyclo[2.2.1]heptan-2-yl]methanone"	""	"example 13 [US8293903]|PF-4634817|PF04634817|PF4634817"	"CO[C@@H]1COCC[C@@H]1N[C@@H]1CC[C@](C1)(C(C)C)C(=O)N1C[C@@H]2C[C@H]1CN2c1ncnc(c1)C(F)(F)F"	"MCRWZBYTLVCCJJ-DKALBXGISA-N"	"InChI=1S/C25H36F3N5O3/c1-15(2)24(6-4-16(10-24)31-19-5-7-36-13-20(19)35-3)23(34)33-12-17-8-18(33)11-32(17)22-9-21(25(26,27)28)29-14-30-22/h9,14-20,31H,4-8,10-13H2,1-3H3/t16-,17+,18+,19+,20-,24+/m1/s1"	"yes"	""	""
"9038"	"PF-04859989"	""	"Synthetic organic"	""	""	""	""	"315661123"	"22868923"	""	""	"CHEMBL2047851"	""	""	""	""	"(3S)-3-amino-1-hydroxy-3,4-dihydroquinolin-2-one"	""	"compound 1 [PMID: 23466229]"	"O=C1[C@@H](N)Cc2c(N1O)cccc2"	"HYTRYTZFJVVZAF-ZETCQYMHSA-N"	"InChI=1S/C9H10N2O2/c10-7-5-6-3-1-2-4-8(6)11(13)9(7)12/h1-4,7,13H,5,10H2/t7-/m0/s1"	"yes"	""	""
"9062"	"PF-04905428"	""	"Synthetic organic"	""	""	""	""	"315661147"	"11547499"	""	""	"CHEMBL1823817"	""	""	""	""	"2-chloro-N-[(1-hydroxycycloheptyl)methyl]-5-[4-[(2R)-2-hydroxy-3-methoxypropyl]-3,5-dioxo-1,2,4-triazin-2-yl]benzamide"	""	"CE-224,535|CE-224535|compound 3 [PMID: 21782426]|compound 33 [PMID: 21565499]"	"COC[C@@H](Cn1c(=O)cnn(c1=O)c1ccc(c(c1)C(=O)NCC1(O)CCCCCC1)Cl)O"	"FUCKCIVGBCBZNP-MRXNPFEDSA-N"	"InChI=1S/C22H29ClN4O6/c1-33-13-16(28)12-26-19(29)11-25-27(21(26)31)15-6-7-18(23)17(10-15)20(30)24-14-22(32)8-4-2-3-5-9-22/h6-7,10-11,16,28,32H,2-5,8-9,12-14H2,1H3,(H,24,30)/t16-/m1/s1"	"yes"	""	""
"9659"	"PF-04957325"	""	"Synthetic organic"	""	""	""	""	"348353618"	"52938379"	""	""	""	""	""	""	""	"3-[[(2R)-4-(1,3-thiazol-2-ylmethyl)morpholin-2-yl]methyl]-5-(trifluoromethyl)triazolo[4,5-d]pyrimidin-7-amine"	""	""	"Nc1nc(nc2c1nnn2C[C@@H]1OCCN(C1)Cc1nccs1)C(F)(F)F"	"VNLPYEMGHGDRRZ-MRVPVSSYSA-N"	"InChI=1S/C14H15F3N8OS/c15-14(16,17)13-20-11(18)10-12(21-13)25(23-22-10)6-8-5-24(2-3-26-8)7-9-19-1-4-27-9/h1,4,8H,2-3,5-7H2,(H2,18,20,21)/t8-/m1/s1"	"yes"	""	""
"9432"	"PF-06263276"	""	"Synthetic organic"	""	""	""	""	"329968373"	"135567296"	""	""	""	""	""	""	""	"2-[6-(2-Ethyl-5- fl uoro-4-hydroxyphenyl)-1 H -indazol-3-yl]- 1,4,6,7-tetrahydroimidazo[4,5- c ]pyridin-5-yl-(5-piperidin-1-yl- pyrazin-2-yl)methanone"	""	"compound 2 [PMID: 27983835]|PF 0626327|PF0626327"	"CCc1cc(O)c(cc1c1ccc2c(c1)[nH]nc2c1nc2c([nH]1)CCN(C2)C(=O)c1cnc(cn1)N1CCCCC1)F"	"XDJGNPSZQSWJCV-UHFFFAOYSA-N"	"InChI=1S/C31H31FN8O2/c1-2-18-13-27(41)22(32)14-21(18)19-6-7-20-24(12-19)37-38-29(20)30-35-23-8-11-40(17-26(23)36-30)31(42)25-15-34-28(16-33-25)39-9-4-3-5-10-39/h6-7,12-16,41H,2-5,8-11,17H2,1H3,(H,35,36)(H,37,38)"	"yes"	""	""
"10053"	"PF-06282999"	""	"Synthetic organic"	""	""	""	""	"375973241"	"71571306"	""	""	"CHEMBL3633460"	""	""	""	""	"2-[6-(5-chloro-2-methoxyphenyl)-4-oxo-2-sulfanylidenepyrimidin-1-yl]acetamide"	""	"compound 8 [PMID: 26509551]|PF06282999"	"COc1ccc(cc1c1cc(=O)[nH]c(=S)n1CC(=O)N)Cl"	"ICYNYWFGIDGBRD-UHFFFAOYSA-N"	"InChI=1S/C13H12ClN3O3S/c1-20-10-3-2-7(14)4-8(10)9-5-12(19)16-13(21)17(9)6-11(15)18/h2-5H,6H2,1H3,(H2,15,18)(H,16,19,21)"	"yes"	""	""
"9666"	"PF-06426779"	""	"Synthetic organic"	""	""	""	""	"348353625"	"118414536"	""	""	""	""	""	""	""	"1-{[(2S,3S,4S)-4-fluoro-3-methyl-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide"	""	"example 189 [WO2015150995]|example 38 [PMID:28498658]"	"COc1cc2c(OC[C@H]3NC(=O)[C@H]([C@H]3C)F)nccc2cc1C(=O)N"	"GISRWBROCYNDME-PELMWDNLSA-N"	"InChI=1S/C17H18FN3O4/c1-8-12(21-16(23)14(8)18)7-25-17-10-6-13(24-2)11(15(19)22)5-9(10)3-4-20-17/h3-6,8,12,14H,7H2,1-2H3,(H2,19,22)(H,21,23)/t8-,12+,14-/m0/s1"	"yes"	""	""
"9565"	"PF-06840003"	""	"Synthetic organic"	""	""	""	""	"336446951"	"23063810"	""	""	""	""	""	""	""	"3-(5-fluoro-1H-indol-3-yl)pyrrolidine-2,5-dione"	""	"EOS200271|PF06840003"	"Fc1cc2c(C3CC(=O)NC3=O)c[nH]c2cc1"	"MXKLDYKORJEOPR-UHFFFAOYSA-N"	"InChI=1S/C12H9FN2O2/c13-6-1-2-10-7(3-6)9(5-14-10)8-4-11(16)15-12(8)17/h1-3,5,8,14H,4H2,(H,15,16,17)"	"yes"	""	""
"11324"	"PF‐06928215"	""	"Synthetic organic"	""	""	""	""	"434321759"	"137300622"	""	""	""	""	""	""	""	"(1R,2S)-2-[(7-oxo-5-phenyl-1H-pyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]cyclohexane-1-carboxylic acid"	""	""	"OC(=O)[C@@H]1CCCC[C@@H]1NC(=O)c1c[nH]n2c1nc(cc2=O)c1ccccc1"	"WGQGCLHXUPGUSZ-HIFRSBDPSA-N"	"InChI=1S/C20H20N4O4/c25-17-10-16(12-6-2-1-3-7-12)22-18-14(11-21-24(17)18)19(26)23-15-9-5-4-8-13(15)20(27)28/h1-3,6-7,10-11,13,15,21H,4-5,8-9H2,(H,23,26)(H,27,28)/t13-,15+/m1/s1"	"yes"	""	""
"11950"	"PF-07038124"	""	"Synthetic organic"	""	""	""	""	"461663505"	"148293990"	""	""	""	""	""	""	""	"3-[(4R)-2-hydroxyoxaborolan-4-yl]-5-(4-methoxy-3-propoxyphenyl)pyridine"	""	"Example 4 [US2020108083A1]|PF07038124"	"CCCOc1cc(ccc1OC)c1cncc(c1)[C@@H]1COB(O)C1"	"KXVKOYCGACSUPP-INIZCTEOSA-N"	"InChI=1S/C18H22BNO4/c1-3-6-23-18-8-13(4-5-17(18)22-2)14-7-15(11-20-10-14)16-9-19(21)24-12-16/h4-5,7-8,10-11,16,21H,3,6,9,12H2,1-2H3/t16-/m0/s1"	"yes"	""	""
"12765"	"PF-07054894"	""	"Synthetic organic"	""	""	""	""	"483123313"	"146444831"	""	""	""	""	""	""	""	"4-[[2-[[(R)-(1,4-dimethylpyrazol-3-yl)-(1-methylcyclopentyl)methyl]amino]-3,4-dioxocyclobuten-1-yl]amino]-3-hydroxy-N,N-dimethylpyridine-2-carboxamide"	""	"PF07054894"	"CN1N=C(C(=C1)C)[C@@H](C2(CCCC2)C)NC3=C(C(C3=O)=O)NC4=C(C(=NC=C4)C(=O)N(C)C)O"	"WZBSYWCLIMRAHO-QFIPXVFZSA-N"	"InChI=1S/C24H30N6O4/c1-13-12-30(5)28-15(13)22(24(2)9-6-7-10-24)27-17-16(20(32)21(17)33)26-14-8-11-25-18(19(14)31)23(34)29(3)4/h8,11-12,22,27,31H,6-7,9-10H2,1-5H3,(H,25,26)/t22-/m0/s1"	"yes"	""	""
"14208"	"PF-07899895"	""	"Synthetic organic"	""	""	""	""	"521588848"	"171101962"	""	""	""	""	""	""	""	"3-[3-[(1-aminocyclohexyl)methoxy]-4-cyano-5-methylsulfanylphenyl]imidazo[1,2-a]pyridine-5-carbonitrile"	""	"example 34 [WO2024062360]|PF07899895"	"CSC1=CC(=CC(=C1C#N)OCC2(CCCCC2)N)C3=CN=C4N3C(=CC=C4)C#N"	"LTQKUGJNXFIXKC-UHFFFAOYSA-N"	"InChI=1S/C23H23N5OS/c1-30-21-11-16(19-14-27-22-7-5-6-17(12-24)28(19)22)10-20(18(21)13-25)29-15-23(26)8-3-2-4-9-23/h5-7,10-11,14H,2-4,8-9,15,26H2,1H3"	"yes"	""	""
"9014"	"PF-152"	""	"Synthetic organic"	""	""	""	""	"310264792"	"25183622"	""	""	""	""	""	""	""	"N-[(4-fluoro-3-methoxyphenyl)methyl]-6-[2-[[(2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl]methyl]tetrazol-5-yl]-2-methylpyrimidine-4-carboxamide"	""	"compound 43a|example 64 [WO2009016498]|PF152"	"OC[C@@H]1CO[C@H](CO1)Cn1nnc(n1)c1nc(C)nc(c1)C(=O)NCc1ccc(c(c1)OC)F"	"SKEAGJWUKCNICJ-LSDHHAIUSA-N"	"InChI=1S/C21H24FN7O5/c1-12-24-17(20-26-28-29(27-20)8-14-10-34-15(9-30)11-33-14)6-18(25-12)21(31)23-7-13-3-4-16(22)19(5-13)32-2/h3-6,14-15,30H,7-11H2,1-2H3,(H,23,31)/t14-,15+/m0/s1"	"yes"	""	""
"9562"	"PFK15"	""	"Synthetic organic"	""	""	""	""	"336446948"	"25142799"	""	""	"CHEMBL3105836"	""	""	""	""	"1-(pyridin-4-yl)-3-(quinolin-2-yl)prop-2-en-1-one"	""	"PFK-015"	"O=C(c1ccncc1)C=Cc1ccc2c(n1)cccc2"	"UJJUKZPBUMCSJZ-UHFFFAOYSA-N"	"InChI=1S/C17H12N2O/c20-17(14-9-11-18-12-10-14)8-7-15-6-5-13-3-1-2-4-16(13)19-15/h1-12H"	"yes"	""	""
"1883"	"PGE<sub>2</sub>"	""	"Metabolite"	"yes"	""	""	""	"135651539"	"5280360"	""	""	"CHEMBL548"	""	""	""	""	"(Z)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]hept-5-enoic acid"	"dinoprostone"	"Cervidil&reg;|minprositin E2|minprostin E2|Propess&reg;|prostaglandin E2"	"CCCCC[C@@H](/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1C/C=C\CCCC(=O)O)O"	"XEYBRNLFEZDVAW-ARSRFYASSA-N"	"InChI=1S/C20H32O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-17,19,21,23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,19+/m0/s1"	"yes"	""	""
"1884"	"PGF<sub>2&alpha;</sub>"	""	"Metabolite"	""	""	""	""	"135651540"	"5280363"	""	""	"CHEMBL815"	""	""	""	""	"(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]cyclopentyl]hept-5-enoic acid"	"dinoprost"	"prostaglandin F<sub>2&alpha;</sub>"	"CCCCC[C@@H](/C=C/[C@H]1[C@H](O)C[C@@H]([C@@H]1C/C=C\CCCC(=O)O)O)O"	"PXGPLTODNUVGFL-YNNPMVKQSA-N"	"InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1"	"yes"	""	""
"7818"	"PH-797804"	""	"Synthetic organic"	""	""	""	""	"223366149"	"22049997"	""	""	"CHEMBL1088751"	""	""	""	""	"3-[3-bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxopyridin-1-yl]-N,4-dimethylbenzamide"	""	""	"CNC(=O)c1ccc(c(c1)n1c(C)cc(c(c1=O)Br)OCc1ccc(cc1F)F)C"	"KCAJXIDMCNPGHZ-UHFFFAOYSA-N"	"InChI=1S/C22H19BrF2N2O3/c1-12-4-5-14(21(28)26-3)9-18(12)27-13(2)8-19(20(23)22(27)29)30-11-15-6-7-16(24)10-17(15)25/h4-10H,11H2,1-3H3,(H,26,28)"	"yes"	""	""
"9398"	"PHA-408"	""	"Synthetic organic"	""	""	""	""	"328083500"	"22291652"	""	""	"CHEMBL592893"	""	""	""	""	"8-[[5-chloro-2-(4-methylpiperazin-1-yl)pyridine-4-carbonyl]amino]-1-(4-fluorophenyl)-4,5-dihydrobenzo[g]indazole-3-carboxamide"	""	"PHA408"	"CN1CCN(CC1)c1ncc(c(c1)C(=O)Nc1ccc2c(c1)c1c(CC2)c(nn1c1ccc(cc1)F)C(=O)N)Cl"	"ZLEZHGHFWIHCGU-UHFFFAOYSA-N"	"InChI=1S/C29H27ClFN7O2/c1-36-10-12-37(13-11-36)25-15-23(24(30)16-33-25)29(40)34-19-6-2-17-3-9-21-26(28(32)39)35-38(27(21)22(17)14-19)20-7-4-18(31)5-8-20/h2,4-8,14-16H,3,9-13H2,1H3,(H2,32,39)(H,34,40)"	"yes"	""	""
"7270"	"phenylbutazone"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178103844"	"4781"	""	""	"CHEMBL101"	""	""	""	""	"4-butyl-1,2-diphenylpyrazolidine-3,5-dione"	"phenylbutazone"	"Butazolidine&reg;"	"CCCCC1C(=O)N(N(C1=O)C2=CC=CC=C2)C3=CC=CC=C3"	"VYMDGNCVAMGZFE-UHFFFAOYSA-N"	"InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,17H,2-3,14H2,1H3"	"yes"	""	""
"11627"	"piclamilast"	""	"Synthetic organic"	""	""	""	""	"442878661"	"154575"	""	""	"CHEMBL42126"	""	""	""	""	"3-cyclopentyloxy-N-(3,5-dichloropyridin-4-yl)-4-methoxybenzamide"	"piclamilast"	"RP 73401|RP-73-401|RP73401"	"COc1ccc(cc1OC1CCCC1)C(=O)Nc1c(Cl)cncc1Cl"	"RRRUXBQSQLKHEL-UHFFFAOYSA-N"	"InChI=1S/C18H18Cl2N2O3/c1-24-15-7-6-11(8-16(15)25-12-4-2-3-5-12)18(23)22-17-13(19)9-21-10-14(17)20/h6-10,12H,2-5H2,1H3,(H,21,22,23)"	"yes"	""	""
"422"	"piclidenoson"	""	"Synthetic organic"	""	""	""	""	"135650362"	"123683"	""	""	"CHEMBL119709"	""	""	""	""	"(2S,3S,4R,5R)-3,4-dihydroxy-5-[6-[(3-iodophenyl)methylamino]purin-9-yl]-N-methyloxolane-2-carboxamide"	"piclidenoson"	"CF 101|CF101|IB-MECA|N(6)-ibamu"	"CNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1cccc(c1)I"	"HUJXGQILHAUCCV-MOROJQBDSA-N"	"InChI=1S/C18H19IN6O4/c1-20-17(28)14-12(26)13(27)18(29-14)25-8-24-11-15(22-7-23-16(11)25)21-6-9-3-2-4-10(19)5-9/h2-5,7-8,12-14,18,26-27H,6H2,1H3,(H,20,28)(H,21,22,23)/t12-,13+,14-,18+/m0/s1"	"yes"	""	""
"7532"	"pirfenidone"	""	"Synthetic organic"	"yes"	""	""	""	"187051833"	"40632"	""	""	"CHEMBL1256391"	""	""	""	""	"5-methyl-1-phenylpyridin-2-one"	"pirfenidone"	"AMR-69|Esbriet&reg;"	"Cc1ccc(=O)n(c1)c1ccccc1"	"ISWRGOKTTBVCFA-UHFFFAOYSA-N"	"InChI=1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3"	"yes"	""	""
"7273"	"piroxicam"	""	"Synthetic organic"	"yes"	""	""	""	"178103847"	"54676228"	""	""	"CHEMBL527"	""	""	""	""	"4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-yl-1&lambda;6,2-benzothiazine-3-carboxamide"	"piroxicam"	"CP-16171|Feldene&reg;"	"OC(=Nc1ccccn1)C1=C(O)c2ccccc2S(=O)(=O)N1C"	"QYSPLQLAKJAUJT-UHFFFAOYSA-N"	"InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)"	"yes"	""	""
"11628"	"pirtobrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"442878662"	"129269915"	""	""	""	""	""	""	""	"5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide"	"pirtobrutinib"	"BTK inhibitor 16|Jaypirca&reg;|LOXO-305|LOXO305|MCL-133|MCL133|RXC005"	"COc1ccc(cc1C(=O)NCc1ccc(cc1)c1nn(c(c1C(=O)N)N)[C@H](C(F)(F)F)C)F"	"FWZAWAUZXYCBKZ-NSHDSACASA-N"	"InChI=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6-13)10-29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32)(H,29,33)/t11-/m0/s1"	"yes"	""	""
"9870"	"pixatimod"	""	"Synthetic organic"	""	""	""	""	"363894164"	"57412325"	""	""	"CHEMBL2078841"	""	""	""	""	""	"pixatimod"	"compound 18 [PMID: 22458531]|PG-545|PG545"	"CC(CCC[C@H]([C@H]1CC[C@@H]2[C@]1(C)CC[C@H]1[C@H]2CC[C@@H]2[C@]1(C)CC[C@@H](C2)O[C@@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1OS(=O)(=O)O)OS(=O)(=O)O)O[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1OS(=O)(=O)O)OS(=O)(=O)O)O[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1OS(=O)(=O)O)OS(=O)(=O)O)O[C@H]1O[C@H](COS(=O)(=O)O)[C@H]([C@@H]([C@H]1OS(=O)(=O)O)OS(=O)(=O)O)OS(=O)(=O)O)C)C"	"LNUFLCYMSVYYNW-ZPJMAFJPSA-N"	"InChI=1S/C51H88O60S13/c1-22(2)7-6-8-23(3)27-11-12-28-26-10-9-24-17-25(13-15-50(24,4)29(26)14-16-51(27,28)5)95-46-42(108-121(79,80)81)38(104-117(67,68)69)34(30(96-46)18-91-112(52,53)54)100-47-43(109-122(82,83)84)39(105-118(70,71)72)35(31(97-47)19-92-113(55,56)57)101-48-44(110-123(85,86)87)40(106-119(73,74)75)36(32(98-48)20-93-114(58,59)60)102-49-45(111-124(88,89)90)41(107-120(76,77)78)37(103-116(64,65)66)33(99-49)21-94-115(61,62)63/h22-49H,6-21H2,1-5H3,(H,52,53,54)(H,55,56,57)(H,58,59,60)(H,61,62,63)(H,64,65,66)(H,67,68,69)(H,70,71,72)(H,73,74,75)(H,76,77,78)(H,79,80,81)(H,82,83,84)(H,85,86,87)(H,88,89,90)/t23-,24+,25+,26+,27-,28+,29+,30-,31-,32-,33-,34-,35-,36-,37-,38+,39+,40+,41+,42-,43-,44-,45-,46-,47-,48-,49-,50+,51-/m1/s1"	"yes"	""	""
"11348"	"PJ34"	""	"Synthetic organic"	""	""	""	""	"440816717"	"4858"	""	""	"CHEMBL372303"	""	""	""	""	"2-(dimethylamino)-N-(6-oxo-5H-phenanthridin-2-yl)acetamide"	""	"PJ-34"	"CN(CC(=O)Nc1ccc2c(c1)c1ccccc1c(=O)[nH]2)C"	"UYJZZVDLGDDTCL-UHFFFAOYSA-N"	"InChI=1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22)"	"yes"	""	""
"9452"	"PKC&theta; inhibitor 14"	""	"Synthetic organic"	""	""	""	""	"329968392"	"91933875"	""	""	""	""	""	""	""	"2,2-dimethyl-7-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)-1-[(1R)-1-phenylethyl]-3H-quinazolin-4-one"	""	"compound 14 [PMID: 27117263]"	"O=C1NC(C)(C)N(c2c1ccc(c2)n1c(=O)[nH]c2c1cccn2)[C@@H](c1ccccc1)C"	"WNYKGJHEQVIFGL-OAHLLOKOSA-N"	"InChI=1S/C24H23N5O2/c1-15(16-8-5-4-6-9-16)29-20-14-17(11-12-18(20)22(30)27-24(29,2)3)28-19-10-7-13-25-21(19)26-23(28)31/h4-15H,1-3H3,(H,27,30)(H,25,26,31)/t15-/m1/s1"	"yes"	""	""
"9141"	"PKUMDL_MH_1001"	""	"Synthetic organic"	""	""	""	""	"315661226"	"11841193"	""	""	""	""	""	""	""	"2-(4-methylpiperazin-1-yl)-1-[(7E)-3-phenyl-7-(phenylmethylidene)-3,3a,4,5,6,7-hexahydro-2H-indazol-2-yl]ethan-1-one"	""	""	"CN1CCN(CC1)CC(=O)N1N=C2C(C1c1ccccc1)CCC/C/2=C\c1ccccc1"	"GEMFAWUXUVGGTE-FCDQGJHFSA-N"	"InChI=1S/C27H32N4O/c1-29-15-17-30(18-16-29)20-25(32)31-27(22-11-6-3-7-12-22)24-14-8-13-23(26(24)28-31)19-21-9-4-2-5-10-21/h2-7,9-12,19,24,27H,8,13-18,20H2,1H3/b23-19+"	"yes"	""	""
"844"	"plerixafor"	""	"Synthetic organic"	"yes"	""	""	""	"135649932"	"65015"	""	""	"CHEMBL18442"	""	""	""	""	"1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane"	"plerixafor"	"AMD 3100|AMD3100|bicyclam JM-2987|JM 3100|Mozobil&reg;"	"C1CNCCN(CCCNCCNC1)Cc1ccc(cc1)CN1CCNCCCNCCNCCC1"	"YIQPUIGJQJDJOS-UHFFFAOYSA-N"	"InChI=1S/C28H54N8/c1-9-29-15-17-31-13-3-21-35(23-19-33-11-1)25-27-5-7-28(8-6-27)26-36-22-4-14-32-18-16-30-10-2-12-34-20-24-36/h5-8,29-34H,1-4,9-26H2"	"yes"	""	""
"11644"	"plonmarlimab"	""	"Antibody"	""	""	""	""	"442878670"	""	""	""	""	""	""	""	""	""	"plonmarlimab"	"TJ 003234|TJ003234|TJM2"	""	""	""	"yes"	""	""
"8921"	"plozalizumab"	""	"Antibody"	""	""	""	""	"310264702"	""	""	""	""	""	""	""	""	""	"plozalizumab"	"hu1D9|MLN-1202|MLN1202"	""	""	""	"yes"	""	""
"9105"	"PLX5622"	""	"Synthetic organic"	""	""	""	""	"315661190"	"52936034"	""	""	"CHEMBL3639728"	""	""	""	""	"6-fluoro-N-[(5-fluoro-2-methoxypyridin-3-yl)methyl]-5-[(5-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]pyridin-2-amine"	""	"PLX 5622|PLX-5622"	"CC1=CC2=C(NC=C2CC3=C(N=C(C=C3)NCC4=C(N=CC(=C4)F)OC)F)N=C1"	"NSMOZFXKTHCPTQ-UHFFFAOYSA-N"	"InChI=1S/C21H19F2N5O/c1-12-5-17-14(9-26-20(17)25-8-12)6-13-3-4-18(28-19(13)23)24-10-15-7-16(22)11-27-21(15)29-2/h3-5,7-9,11H,6,10H2,1-2H3,(H,24,28)(H,25,26)"	"yes"	""	""
"9104"	"PLX7486"	""	"Synthetic organic"	""	""	""	""	"315661189"	""	""	""	""	""	""	""	""	""	""	"OPN 7486|OPN-7486|PLX-7486"	""	""	""	"yes"	""	""
"5762"	"PMX205"	""	"Peptide"	""	""	""	""	"178102387"	"6918845"	""	""	""	""	""	""	""	"N-[(3S,9S,12S,15R,18S)-15-(cyclohexylmethyl)-9-[3-(diaminomethylideneamino)propyl]-12-(1H-indol-3-ylmethyl)-2,8,11,14,17-pentaoxo-1,7,10,13,16-pentazabicyclo[16.3.0]henicosan-3-yl]-3-phenylpropanamide"	""	"ALS-205|PMX 205|PMX-205"	"C1CCC(CC1)C[C@@H]2C(=O)N[C@H](C(=O)N[C@H](C(=O)NCCC[C@@H](C(=O)N3CCC[C@H]3C(=O)N2)NC(=O)CCC4=CC=CC=C4)CCCN=C(N)N)CC5=CNC6=CC=CC=C65"	"VATFHFJULBPYLM-ILOBPARPSA-N"	"InChI=1S/C45H62N10O6/c46-45(47)49-24-9-18-34-40(57)48-23-10-19-35(51-39(56)22-21-29-12-3-1-4-13-29)44(61)55-25-11-20-38(55)43(60)54-36(26-30-14-5-2-6-15-30)41(58)53-37(42(59)52-34)27-31-28-50-33-17-8-7-16-32(31)33/h1,3-4,7-8,12-13,16-17,28,30,34-38,50H,2,5-6,9-11,14-15,18-27H2,(H,48,57)(H,51,56)(H,52,59)(H,53,58)(H,54,60)(H4,46,47,49)/t34-,35-,36+,37-,38-/m0/s1"	"yes"	""	""
"10089"	"PN10"	""	"Synthetic organic"	""	""	""	""	"381118799"	"90448438"	""	""	""	""	""	""	""	"5-[(7-chloro-1H-indol-3-yl)methyl]-3-[4-[3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methylphenyl]butyl]imidazolidine-2,4-dione"	""	""	"O=C1NC(C(=O)N1CCCCc1ccc(c(c1)C#Cc1cnc2n1nccc2)C)Cc1c[nH]c2c1cccc2Cl"	"ZQSZVECJMJELSV-UHFFFAOYSA-N"	"InChI=1S/C31H27ClN6O2/c1-20-10-11-21(16-22(20)12-13-24-19-33-28-9-5-14-35-38(24)28)6-2-3-15-37-30(39)27(36-31(37)40)17-23-18-34-29-25(23)7-4-8-26(29)32/h4-5,7-11,14,16,18-19,27,34H,2-3,6,15,17H2,1H3,(H,36,40)"	"yes"	""	""
"10739"	"PO-322"	""	"Synthetic organic"	""	""	""	""	"405067332"	"185135"	""	""	""	""	""	""	""	"3-(1,3-benzoxazol-2-yldiazenyl)-1H-indol-2-ol"	""	"1H-indole-2,3-dione 3-(1,3-benzoxazol-2-ylhydrazone)|PO322"	"O=C1Nc2c(C1=NNc1nc3c(o1)cccc3)cccc2"	"NWUCBUGDPJNKAC-UHFFFAOYSA-N"	"InChI=1S/C15H10N4O2/c20-14-13(9-5-1-2-6-10(9)16-14)18-19-15-17-11-7-3-4-8-12(11)21-15/h1-8H,(H,17,19)(H,16,18,20)"	"yes"	""	""
"8404"	"polatuzumab vedotin"	""	"Antibody"	"yes"	""	""	""	"252166614"	""	""	""	""	""	""	""	""	""	"polatuzumab vedotin"	"ACD79B-VCMMAE|polatuzumab vedotin-piiq|Polivy&reg;|RG-7596|RG7596|RO5541077-000"	""	""	""	"yes"	""	""
"8316"	"polmacoxib"	""	"Synthetic organic"	"yes"	""	""	""	"252166528"	"9841854"	""	""	"CHEMBL166863"	""	""	""	""	"4-[3-(3-fluorophenyl)-5,5-dimethyl-4-oxofuran-2-yl]benzenesulfonamide"	"polmacoxib"	"Acelex&reg; (S. Korea)|CG-100649|CG100649"	"Fc1cccc(c1)C1=C(OC(C1=O)(C)C)c1ccc(cc1)S(=O)(=O)N"	"IJWPAFMIFNSIGD-UHFFFAOYSA-N"	"InChI=1S/C18H16FNO4S/c1-18(2)17(21)15(12-4-3-5-13(19)10-12)16(24-18)11-6-8-14(9-7-11)25(20,22)23/h3-10H,1-2H3,(H2,20,22,23)"	"yes"	""	""
"9616"	"POM2-C-HMBP"	""	"Synthetic organic"	""	""	""	""	"340590246"	"91864624"	""	""	""	""	""	""	""	"[2,2-dimethylpropanoyloxymethoxy-[(E)-5-hydroxy-4-methylpent-3-enyl]phosphoryl]oxymethyl 2,2-dimethylpropanoate"	""	""	"OC/C(=C/CCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)/C"	"IPOCPVGCROEFJO-NTEUORMPSA-N"	"InChI=1S/C18H33O8P/c1-14(11-19)9-8-10-27(22,25-12-23-15(20)17(2,3)4)26-13-24-16(21)18(5,6)7/h9,19H,8,10-13H2,1-7H3/b14-9+"	"yes"	""	""
"7348"	"pomalidomide"	""	"Synthetic organic"	"yes"	""	""	""	"178103920"	"134780"	""	""	"CHEMBL43452"	""	""	""	""	"4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione"	"pomalidomide"	"CC-4047|IMID-3|Imnovid&reg;|Pomalyst&reg;"	"O=C1CCC(C(=O)N1)N1C(=O)c2c(C1=O)c(N)ccc2"	"UVSMNLNDYGZFPF-UHFFFAOYSA-N"	"InChI=1S/C13H11N3O4/c14-7-3-1-2-6-10(7)13(20)16(12(6)19)8-4-5-9(17)15-11(8)18/h1-3,8H,4-5,14H2,(H,15,17,18)"	"yes"	""	""
"5890"	"ponatinib"	""	"Synthetic organic"	"yes"	""	""	""	"178102513"	"24826799"	""	""	"CHEMBL1171837"	""	""	""	""	"3-(2-imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]benzamide"	"ponatinib"	"AP24534|Iclusig&reg;"	"CN1CCN(CC1)Cc1ccc(cc1C(F)(F)F)NC(=O)c1ccc(c(c1)C#Cc1cnc2n1nccc2)C"	"PHXJVRSECIGDHY-UHFFFAOYSA-N"	"InChI=1S/C29H27F3N6O/c1-20-5-6-22(16-21(20)8-10-25-18-33-27-4-3-11-34-38(25)27)28(39)35-24-9-7-23(26(17-24)29(30,31)32)19-37-14-12-36(2)13-15-37/h3-7,9,11,16-18H,12-15,19H2,1-2H3,(H,35,39)"	"yes"	""	""
"9320"	"ponesimod"	""	"Synthetic organic"	"yes"	""	""	""	"318164839"	"11363176"	""	""	"CHEMBL1096146"	""	""	""	""	"(5Z)-5-[[3-chloro-4-[(2R)-2,3-dihydroxypropoxy]phenyl]methylidene]-3-(2-methylphenyl)-2-propylimino-1,3-thiazolidin-4-one"	"ponesimod"	"ACT-128800|ACT128800|Compound 8bo [PMID:20446681]|Ponvory&reg;"	"CCCN=C1S/C(=C\c2ccc(c(c2)Cl)OC[C@@H](CO)O)/C(=O)N1c1ccccc1C"	"LPAUOXUZGSBGDU-ULCCENQXSA-N"	"InChI=1S/C23H25ClN2O4S/c1-3-10-25-23-26(19-7-5-4-6-15(19)2)22(29)21(31-23)12-16-8-9-20(18(24)11-16)30-14-17(28)13-27/h4-9,11-12,17,27-28H,3,10,13-14H2,1-2H3/b21-12-,25-23?/t17-/m1/s1"	"yes"	""	""
"9862"	"poseltinib"	""	"Synthetic organic"	""	""	""	""	"363894156"	"56644522"	""	""	""	""	""	""	""	"N-[3-[2-[4-(4-methylpiperazin-1-yl)anilino]furo[3,2-d]pyrimidin-4-yl]oxyphenyl]prop-2-enamide"	"poseltinib"	"Example 228 [WO2011162515A2]|HM71224|HM‐71224|LY333764"	"C=CC(=O)Nc1cccc(c1)Oc1nc(Nc2ccc(cc2)N2CCN(CC2)C)nc2c1occ2"	"LZMJNVRJMFMYQS-UHFFFAOYSA-N"	"InChI=1S/C26H26N6O3/c1-3-23(33)27-19-5-4-6-21(17-19)35-25-24-22(11-16-34-24)29-26(30-25)28-18-7-9-20(10-8-18)32-14-12-31(2)13-15-32/h3-11,16-17H,1,12-15H2,2H3,(H,27,33)(H,28,29,30)"	"yes"	""	""
"14426"	"povetacicept"	""	"Peptide"	""	""	""	""	"523352218"	""	""	""	""	""	""	""	""	""	"povetacicept"	"ALPN-303|TACI vTD-Fc"	""	""	""	"yes"	""	""
"11881"	"povorcitinib"	""	"Synthetic organic"	""	""	""	""	"461663437"	"86280672"	""	""	""	""	""	""	""	"4-[3-(cyanomethyl)-3-[4-(3,5-dimethyl-1H-pyrazol-4-yl)pyrazol-1-yl]azetidin-1-yl]-2,5-difluoro-N-[(2S)-1,1,1-trifluoropropan-2-yl]benzamide"	"povorcitinib"	"compound 7 [US20210238168A1]"	"C(#N)CC1(CN(C1)c1cc(c(C(=O)N[C@H](C(F)(F)F)C)cc1F)F)n1ncc(c1)c1c(n[nH]c1C)C"	"MSGYSFWCPOBHEV-AWEZNQCLSA-N"	"InChI=1S/C23H22F5N7O/c1-12-20(13(2)33-32-12)15-8-30-35(9-15)22(4-5-29)10-34(11-22)19-7-17(24)16(6-18(19)25)21(36)31-14(3)23(26,27)28/h6-9,14H,4,10-11H2,1-3H3,(H,31,36)(H,32,33)/t14-/m0/s1"	"yes"	""	""
"12900"	"pozelimab"	""	"Antibody"	"yes"	""	""	""	"485206021"	""	""	""	""	""	""	""	""	""	"pozelimab"	"pozelimab-bbfg|REGN-3918|REGN3918|Veopoz&reg;"	""	""	""	"yes"	""	""
"9404"	"PP2"	""	"Synthetic organic"	""	""	""	""	"328083506"	"4878"	""	""	"CHEMBL406845"	""	""	""	""	"1-tert-butyl-3-(4-chlorophenyl)pyrazolo[4,5-e]pyrimidin-4-amine"	""	""	"Clc1ccc(cc1)c1nn(c2c1c(N)ncn2)C(C)(C)C"	"PBBRWFOVCUAONR-UHFFFAOYSA-N"	"InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)"	"yes"	""	""
"9454"	"PQA-18"	""	"Synthetic organic"	""	""	""	""	"329968394"	"46910769"	""	""	"CHEMBL3355920"	""	""	""	""	"3-methylbut-2-enyl 4-methoxy-8-(3-methylbut-2-enoxy)quinoline-2-carboxylate"	""	""	"CC(=CCOc1cc(nc2c1cccc2OCC=C(C)C)C(=O)OCC=C(C)C)C"	"APPXFGJVXDYNBO-UHFFFAOYSA-N"	"InChI=1S/C25H31NO4/c1-17(2)10-13-28-22-9-7-8-20-23(29-14-11-18(3)4)16-21(26-24(20)22)25(27)30-15-12-19(5)6/h7-12,16H,13-15H2,1-6H3"	"yes"	""	""
"9900"	"praliciguat"	""	"Synthetic organic"	""	""	""	""	"363894194"	"86269973"	""	""	""	""	""	""	""	"1,1,1-trifluoro-3-[(5-fluoro-2-{1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)-1H-pyrazol-3-yl}pyrimidin-4-yl)amino]-2-(trifluoromethyl)propan-2-ol"	"praliciguat"	"IW-1973|IW1973"	"Fc1cnc(nc1NCC(C(F)(F)F)(C(F)(F)F)O)c1nn(c(c1)c1nocc1)Cc1ccccc1F"	"CYSJNTQNMDWAJV-UHFFFAOYSA-N"	"InChI=1S/C21H14F8N6O2/c22-12-4-2-1-3-11(12)9-35-16(14-5-6-37-34-14)7-15(33-35)18-30-8-13(23)17(32-18)31-10-19(36,20(24,25)26)21(27,28)29/h1-8,36H,9-10H2,(H,30,31,32)"	"yes"	""	""
"6467"	"pralnacasan"	""	"Synthetic organic"	""	""	""	""	"178103081"	"153270"	""	""	"CHEMBL437526"	""	""	""	""	"(1S,9S)-N-[(2R,3S)-2-ethoxy-5-oxooxolan-3-yl]-9-(isoquinoline-1-carbonylamino)-6,10-dioxo-2,3,4,7,8,9-hexahydro-1H-pyridazino[1,2-a]diazepine-1-carboxamide"	"pralnacasan"	"VX-740|VX740"	"CCO[C@@H]1OC(=O)C[C@@H]1NC(=O)[C@@H]1CCCN2N1C(=O)[C@H](CCC2=O)NC(=O)c1nccc2c1cccc2"	"CXAGHAZMQSCAKJ-WAHHBDPQSA-N"	"InChI=1S/C26H29N5O7/c1-2-37-26-18(14-21(33)38-26)29-23(34)19-8-5-13-30-20(32)10-9-17(25(36)31(19)30)28-24(35)22-16-7-4-3-6-15(16)11-12-27-22/h3-4,6-7,11-12,17-19,26H,2,5,8-10,13-14H2,1H3,(H,28,35)(H,29,34)/t17-,18-,19-,26+/m0/s1"	"yes"	""	""
"3634"	"pranlukast"	""	"Synthetic organic"	"yes"	""	""	""	"178100541"	"4887"	""	""	"CHEMBL21333"	""	""	""	""	"N-[4-oxo-2-(2H-tetrazol-5-yl)chromen-8-yl]-4-(4-phenylbutoxy)benzamide"	"pranlukast"	"ONO RS-411"	"O=C(c1ccc(cc1)OCCCCc1ccccc1)Nc1cccc2c1oc(cc2=O)c1[nH]nnn1"	"NBQKINXMPLXUET-UHFFFAOYSA-N"	"InChI=1S/C27H23N5O4/c33-23-17-24(26-29-31-32-30-26)36-25-21(23)10-6-11-22(25)28-27(34)19-12-14-20(15-13-19)35-16-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-15,17H,4-5,9,16H2,(H,28,34)(H,29,30,31,32)"	"yes"	""	""
"7605"	"prednicarbate"	""	"Synthetic organic"	"yes"	""	""	""	"223365940"	"6714002"	""	""	"CHEMBL1200386"	""	""	""	""	"[2-[(8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate"	"prednicarbate"	"Dermatop&reg;|Hoe 777|Hoe-777|S-770777"	"CCOC(=O)O[C@@]1(CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C)C(=O)COC(=O)CC"	"FNPXMHRZILFCKX-KAJVQRHHSA-N"	"InChI=1S/C27H36O8/c1-5-22(31)34-15-21(30)27(35-24(32)33-6-2)12-10-19-18-8-7-16-13-17(28)9-11-25(16,3)23(18)20(29)14-26(19,27)4/h9,11,13,18-20,23,29H,5-8,10,12,14-15H2,1-4H3/t18-,19-,20-,23+,25-,26-,27-/m0/s1"	"yes"	""	""
"2866"	"prednisolone"	""	"Synthetic organic"	"yes"	""	""	""	"135650850"	"5755"	""	""	"CHEMBL131"	""	""	""	""	"(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one"	"prednisolone"	"DELTA.1-Cortisol|Orapred&reg;|Pediapred&reg;"	"OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C"	"OIGNJSKKLXVSLS-VWUMJDOOSA-N"	"InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1"	"yes"	""	""
"7096"	"prednisone"	""	"Synthetic organic"	"yes"	""	""	""	"178103674"	"5865"	""	""	"CHEMBL635"	""	""	""	""	"(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione"	"prednisone"	"Lodotra&reg;|Sterapred&reg;"	"OCC(=O)[C@@]1(O)CC[C@@H]2[C@]1(C)CC(=O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C"	"XOFYZVNMUHMLCC-ZPOLXVRWSA-N"	"InChI=1S/C21H26O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-15,18,22,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,18+,19-,20-,21-/m0/s1"	"yes"	""	""
"5614"	"preladenant"	""	"Synthetic organic"	""	""	""	""	"178102248"	"10117987"	""	""	"CHEMBL240624"	""	""	""	""	""	"preladenant"	"SCH-420814|SCH420814"	"COCCOc1ccc(cc1)N1CCN(CC1)CCn1ncc2c1nc(N)n1c2nc(n1)c1ccco1"	"DTYWJKSSUANMHD-UHFFFAOYSA-N"	"InChI=1S/C25H29N9O3/c1-35-15-16-36-19-6-4-18(5-7-19)32-11-8-31(9-12-32)10-13-33-23-20(17-27-33)24-28-22(21-3-2-14-37-21)30-34(24)25(26)29-23/h2-7,14,17H,8-13,15-16H2,1H3,(H2,26,29)"	"yes"	""	""
"9285"	"PRN694"	""	"Synthetic organic"	""	""	""	""	"318164804"	"90044055"	""	""	""	""	""	""	""	"5-(difluoromethyl)-N-[5-[[[(2S)-3,3-dimethylbutan-2-yl]amino]methyl]-1-[[(2R)-1-prop-2-enoylpyrrolidin-2-yl]methyl]benzimidazol-2-yl]thiophene-2-carboxamide"	""	""	"C=CC(=O)N1CCC[C@@H]1Cn1c(NC(=O)c2ccc(s2)C(F)F)nc2c1ccc(c2)CN[C@H](C(C)(C)C)C"	"NXTKFBGDLDPFLB-PKOBYXMFSA-N"	"InChI=1S/C28H35F2N5O2S/c1-6-24(36)34-13-7-8-19(34)16-35-21-10-9-18(15-31-17(2)28(3,4)5)14-20(21)32-27(35)33-26(37)23-12-11-22(38-23)25(29)30/h6,9-12,14,17,19,25,31H,1,7-8,13,15-16H2,2-5H3,(H,32,33,37)/t17-,19+/m0/s1"	"yes"	""	""
"3464"	"procaterol"	""	"Synthetic organic"	"yes"	""	""	""	"53801069"	"4916"	""	""	"CHEMBL160519"	""	""	""	""	"8-hydroxy-5-[1-hydroxy-2-(propan-2-ylamino)butyl]-1H-quinolin-2-one"	"procaterol"	""	"CCC(C(c1ccc(c2c1ccc(=O)[nH]2)O)O)NC(C)C"	"FKNXQNWAXFXVNW-UHFFFAOYSA-N"	"InChI=1S/C16H22N2O3/c1-4-12(17-9(2)3)16(21)11-5-7-13(19)15-10(11)6-8-14(20)18-15/h5-9,12,16-17,19,21H,4H2,1-3H3,(H,18,20)"	"yes"	""	""
"9606"	"programmed cell death 1 ligand 1"	"Human"	"Peptide"	""	""	""	""	"340590236"	""	"Q9NZQ7"	"ENSG00000120217"	""	""	""	""	""	""	""	"B7 homolog 1|B7-H1|PD-L1|PDL1|programmed death ligand 1"	""	""	""	"yes"	""	""
"12991"	"prolgolimab"	""	"Antibody"	""	""	""	""	"485206112"	""	""	""	""	""	""	""	""	""	"prolgolimab"	"BCD-100|BCD100"	""	""	""	"yes"	""	""
"13783"	"proximod"	""	"Synthetic organic"	""	""	""	""	"507750416"	"71487030"	""	""	"CHEMBL3782066"	""	""	""	""	"2-amino-2-[2-[4-[4-(2-propyl-1,3-oxazol-4-yl)phenyl]phenyl]ethyl]propane-1,3-diol"	""	"compound 53b [Tian <i>et al</i>., 2013]|IMMH001|LJR001|SYL930"	"CCCC1=NC(=CO1)C2=CC=C(C=C2)C3=CC=C(C=C3)CCC(CO)(CO)N"	"SJXISVAGHMLUDT-UHFFFAOYSA-N"	"InChI=1S/C23H28N2O3/c1-2-3-22-25-21(14-28-22)20-10-8-19(9-11-20)18-6-4-17(5-7-18)12-13-23(24,15-26)16-27/h4-11,14,26-27H,2-3,12-13,15-16,24H2,1H3"	"yes"	""	""
"3286"	"PSB1115"	""	"Synthetic organic"	""	""	""	""	"178100327"	"5311479"	""	""	"CHEMBL8565"	""	""	""	""	"4-(2,6-dioxo-1-propyl-1,2,3,6-tetrahydropurin-8-yl)benzene-1-sulfonic acid"	""	"compound 17 [PMID: 11906291]|PSB 1115|PSB-1115"	"CCCn1c(=O)[nH]c2c(c1=O)nc([nH]2)c1ccc(cc1)S(=O)(=O)O"	"UYDRRQPGDSIMNU-UHFFFAOYSA-N"	"InChI=1S/C14H14N4O5S/c1-2-7-18-13(19)10-12(17-14(18)20)16-11(15-10)8-3-5-9(6-4-8)24(21,22)23/h3-6H,2,7H2,1H3,(H,15,16)(H,17,20)(H,21,22,23)"	"yes"	""	""
"9871"	"PSB-17365"	""	"Synthetic organic"	""	""	""	""	"363894165"	"133081959"	""	""	""	""	""	""	""	"6-{[2-(4-bromophenyl)ethyl]amino}-1,2,3,4-tetrahydropyrimidine-2,4-dione"	""	"compound 48 [Pillaiyar <i>et al.</i>, 2018]|PSB17365"	"Brc1ccc(cc1)CCNc1cc(=O)[nH]c(=O)[nH]1"	"XGNIAOMGYRRHNY-UHFFFAOYSA-N"	"InChI=1S/C12H12BrN3O2/c13-9-3-1-8(2-4-9)5-6-14-10-7-11(17)16-12(18)15-10/h1-4,7H,5-6H2,(H3,14,15,16,17,18)"	"yes"	""	""
"11081"	"PSB-KD107"	""	"Synthetic organic"	""	""	""	""	"434122142"	"44437220"	""	""	"CHEMBL239232"	""	""	""	""	"9-[2-(1H-indol-3-yl)ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione"	""	"compound 2Ak [PMID: 17827019]|compound 5 [Schoeder <i>et al</i>., 2020]"	"Cn1c(=O)n(C)c(=O)c2c1nc1n2CCCN1CCc1c[nH]c2c1cccc2"	"PUJKERUFRDZALE-UHFFFAOYSA-N"	"InChI=1S/C20H22N6O2/c1-23-17-16(18(27)24(2)20(23)28)26-10-5-9-25(19(26)22-17)11-8-13-12-21-15-7-4-3-6-14(13)15/h3-4,6-7,12,21H,5,8-11H2,1-2H3"	"yes"	""	""
"9583"	"psora-4"	""	"Synthetic organic"	""	""	""	""	"340590214"	"6603977"	""	""	"CHEMBL1256851"	""	""	""	""	"4-(4-phenylbutoxy)furo[3,2-g]chromen-7-one"	""	"5-(4-phenylbutoxy)psoralen|psora 4"	"O=c1ccc2c(o1)cc1c(c2OCCCCc2ccccc2)cco1"	"JJAWGNIQEOFURP-UHFFFAOYSA-N"	"InChI=1S/C21H18O4/c22-20-10-9-16-19(25-20)14-18-17(11-13-23-18)21(16)24-12-5-4-8-15-6-2-1-3-7-15/h1-3,6-7,9-11,13-14H,4-5,8,12H2"	"yes"	""	""
"9753"	"PXS-4681A"	""	"Synthetic organic"	""	""	""	""	"354702226"	"72190183"	""	""	""	""	""	""	""	"4-[(E)-2-(aminomethyl)-3-fluoroprop-2-enoxy]benzenesulfonamide"	""	""	"NC/C(=C\F)/COc1ccc(cc1)S(=O)(=O)N"	"GJRSZKOPZAJCGZ-VMPITWQZSA-N"	"InChI=1S/C10H13FN2O3S/c11-5-8(6-12)7-16-9-1-3-10(4-2-9)17(13,14)15/h1-5H,6-7,12H2,(H2,13,14,15)/b8-5+"	"yes"	""	""
"9346"	"PXS-4728A"	""	"Synthetic organic"	""	""	""	""	"328083448"	"71812247"	""	""	""	""	""	""	""	"4-[(E)-2-(aminomethyl)-3-fluoroprop-2-enoxy]-N-tert-butylbenzamide"	""	"PXS4728A"	"NC/C(=C\F)/COc1ccc(cc1)C(=O)NC(C)(C)C"	"OWNSXNXYELKDSO-DHZHZOJOSA-N"	"InChI=1S/C15H21FN2O2/c1-15(2,3)18-14(19)12-4-6-13(7-5-12)20-10-11(8-16)9-17/h4-8H,9-10,17H2,1-3H3,(H,18,19)/b11-8+"	"yes"	""	""
"8996"	"QAV680"	""	"Synthetic organic"	""	""	""	""	"310264774"	"11508736"	""	""	"CHEMBL2442750"	""	""	""	""	"2-[2-methyl-1-[(4-methylsulfonylphenyl)methyl]pyrrolo[5,4-b]pyridin-3-yl]acetic acid"	""	"NVP-QAV680"	"OC(=O)Cc1c(C)n(c2c1cccn2)Cc1ccc(cc1)S(=O)(=O)C"	"YOPFAMROKXHVCQ-UHFFFAOYSA-N"	"InChI=1S/C18H18N2O4S/c1-12-16(10-17(21)22)15-4-3-9-19-18(15)20(12)11-13-5-7-14(8-6-13)25(2,23)24/h3-9H,10-11H2,1-2H3,(H,21,22)"	"yes"	""	""
"13890"	"quavonlimab"	""	"Antibody"	""	""	""	""	"513757575"	""	""	""	""	""	""	""	""	""	"quavonlimab"	"MK-1308|MK1308"	""	""	""	"yes"	""	""
"14064"	"quecitinib"	""	"Synthetic organic"	""	""	""	""	"518520691"	"156188109"	""	""	""	""	""	""	""	""	"quecitinib"	"QY-201|QY201|VVN-461|VVN461"	"O[C@H](C)C1=NC=2C(=C3C(=NC2)NC=C3)N1N4CCC(CC4)CC#N"	"LUQHXRXPKKQUKV-LLVKDONJSA-N"	"InChI=1S/C17H20N6O/c1-11(24)17-21-14-10-20-16-13(3-7-19-16)15(14)23(17)22-8-4-12(2-6-18)5-9-22/h3,7,10-12,24H,2,4-5,8-9H2,1H3,(H,19,20)/t11-/m1/s1"	"yes"	""	""
"10707"	"quemliclustat"	""	"Synthetic organic"	""	""	""	""	"404859154"	"130205852"	""	""	""	""	""	""	""	"[[(2R,3S,4R,5R)-5-[6-chloro-4-[[(1S)-1-(2-fluorophenyl)ethyl]amino]pyrazolo[3,4-b]pyridin-1-yl]-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]methylphosphonic acid"	"quemliclustat"	"AB-680|AB680"	"O[C@@H]1[C@H](O)[C@H](O[C@H]1n1ncc2c1nc(Cl)cc2N[C@H](c1ccccc1F)C)COP(=O)(CP(=O)(O)O)O"	"MFYLCAMJNGIULC-KCVUFLITSA-N"	"InChI=1S/C20H24ClFN4O9P2/c1-10(11-4-2-3-5-13(11)22)24-14-6-16(21)25-19-12(14)7-23-26(19)20-18(28)17(27)15(35-20)8-34-37(32,33)9-36(29,30)31/h2-7,10,15,17-18,20,27-28H,8-9H2,1H3,(H,24,25)(H,32,33)(H2,29,30,31)/t10-,15+,17+,18+,20+/m0/s1"	"yes"	""	""
"8998"	"quilizumab"	""	"Antibody"	""	""	""	""	"310264776"	""	""	""	""	""	""	""	""	""	"quilizumab"	"47H4 v5 hulgG1|MEMP1972A|RG-7449"	""	""	""	"yes"	""	""
"9568"	"QWF"	""	"Peptide"	""	""	""	""	"336446954"	""	""	""	""	""	""	""	""	""	""	"Boc-Gln-D-Trp(CH0)-Phe-OBzl|N<sup>&alpha;</sup>-[N<sup>&alpha;</sup>-[N<sup>&alpha;</sup>-(tert-butyloxycabonyl)-L-glutaminyl]-N<sup>1</sup>-formyl-D-tryptophyl-L-phenylalanine benzyl ester"	""	""	""	"yes"	""	""
"10049"	"R283"	""	"Synthetic organic"	""	""	""	""	"375973237"	"123415149"	""	""	""	""	""	""	""	"3-(1,3-dimethylimidazol-1-ium-2-yl)sulfanylpropanal"	""	"1,3-Dimethyl-2[(oxopropyl)thio]imidazolium"	"O=CCCSc1n(C)cc[n+]1C"	"NAQRMIYTJDQSRI-UHFFFAOYSA-N"	"InChI=1S/C8H13N2OS/c1-9-4-5-10(2)8(9)12-7-3-6-11/h4-6H,3,7H2,1-2H3/q+1"	"yes"	""	""
"10487"	"RA839"	""	"Synthetic organic"	""	""	""	""	"385612246"	"91971266"	""	""	"CHEMBL3899754"	""	""	""	""	"(3S)-1-[4-[(2,3,5,6-tetramethylphenyl)sulfonylamino]naphthalen-1-yl]pyrrolidine-3-carboxylic acid"	""	"compound 7 [PMID: 31411465]|RA-839"	"OC(=O)[C@H]1CCN(C1)c1ccc(c2c1cccc2)NS(=O)(=O)c1c(C)c(C)cc(c1C)C"	"BVYWIQHJXAEJOD-IBGZPJMESA-N"	"InChI=1S/C25H28N2O4S/c1-15-13-16(2)18(4)24(17(15)3)32(30,31)26-22-9-10-23(21-8-6-5-7-20(21)22)27-12-11-19(14-27)25(28)29/h5-10,13,19,26H,11-12,14H2,1-4H3,(H,28,29)/t19-/m0/s1"	"yes"	""	""
"9856"	"rabeximod"	""	"Synthetic organic"	""	""	""	""	"363894150"	"56841552"	""	""	""	""	""	""	""	"2-(9-chloro-2,3-dimethylindolo[3,2-b]quinoxalin-6-yl)-N-[2-(dimethylamino)ethyl]acetamide"	"rabeximod"	"Rob-803|Rob803"	"CN(CCNC(=O)Cn1c2ccc(cc2c2c1nc1cc(C)c(cc1n2)C)Cl)C"	"PDNNUMNEXITLCZ-UHFFFAOYSA-N"	"InChI=1S/C22H24ClN5O/c1-13-9-17-18(10-14(13)2)26-22-21(25-17)16-11-15(23)5-6-19(16)28(22)12-20(29)24-7-8-27(3)4/h5-6,9-11H,7-8,12H2,1-4H3,(H,24,29)"	"yes"	""	""
"5066"	"RANK ligand"	"Human"	"Peptide"	""	""	""	""	"178101759"	""	"O14788"	"ENSG00000120659"	""	""	""	""	""	""	""	"<u><b>r</b></u>eceptor <u><b>a</b></u>ctivator of <u><b>n</b></u>uclear factor <u><b>&kappa;</b></u>B <u><b>l</b></u>igand|osteoclast differentiation factor (ODF)|osteoprotegerin ligand|TNFSF11"	""	""	""	"yes"	""	""
"10168"	"ravulizumab"	""	"Antibody"	"yes"	""	""	""	"381118878"	""	""	""	""	""	""	""	""	""	"ravulizumab"	"ALXN-1210|ALXN1210|ravulizumab-cwvz|Ultomiris&reg;"	""	""	""	"yes"	""	""
"13782"	"(R)-DFV890"	""	"Synthetic organic"	""	""	""	""	"507750415"	"137443244"	""	""	""	""	""	""	""	""	""	"compound (R)-1 [PMID: 40036600]|DFV-890|IFM-2427|IFM2427"	"CC(C)(O)C1=NC=C([S@](N)(=O)=NC(=O)NC2=C3CCCC3=CC4=C2CCC4)S1"	"LHVWNNYPUDZLSH-MUUNZHRXSA-N"	"InChI=1S/C19H24N4O3S2/c1-19(2,25)17-21-10-15(27-17)28(20,26)23-18(24)22-16-13-7-3-5-11(13)9-12-6-4-8-14(12)16/h9-10,25H,3-8H2,1-2H3,(H3,20,22,23,24,26)/t28-/m1/s1"	"yes"	""	""
"9173"	"rebastinib"	""	"Synthetic organic"	""	""	""	""	"315661256"	"25066467"	""	""	"CHEMBL1738757"	""	""	""	""	"4-[4-[(5-tert-butyl-2-quinolin-6-ylpyrazol-3-yl)carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide"	"rebastinib"	"DCC 2036|DCC-2036|DP-1919"	"CNC(=O)c1nccc(c1)Oc1ccc(c(c1)F)NC(=O)Nc1cc(nn1c1ccc2c(c1)cccn2)C(C)(C)C"	"WVXNSAVVKYZVOE-UHFFFAOYSA-N"	"InChI=1S/C30H28FN7O3/c1-30(2,3)26-17-27(38(37-26)19-7-9-23-18(14-19)6-5-12-33-23)36-29(40)35-24-10-8-20(15-22(24)31)41-21-11-13-34-25(16-21)28(39)32-4/h5-17H,1-4H3,(H,32,39)(H2,35,36,40)"	"yes"	""	""
"13830"	"relacorilant"	""	"Synthetic organic"	"yes"	""	""	""	"507750463"	"73051463"	""	""	"CHEMBL4068611"	""	""	""	""	"[(4aR)-1-(4-fluorophenyl)-6-(1-methylpyrazol-4-yl)sulfonyl-4,5,7,8-tetrahydropyrazolo[3,4-g]isoquinolin-4a-yl]-[4-(trifluoromethyl)pyridin-2-yl]methanone"	"relacorilant"	"compound 7 [PMID: 28368581]|CORT-125134|CORT125134|Lifyorli&reg;"	"CN1C=C(C=N1)S(=O)(=O)N2CCC3=CC4=C(C[C@@]3(C2)C(=O)C5=NC=CC(=C5)C(F)(F)F)C=NN4C6=CC=C(C=C6)F"	"WANIDIGFXJFFEL-SANMLTNESA-N"	"InChI=1S/C27H22F4N6O3S/c1-35-15-22(14-33-35)41(39,40)36-9-7-18-11-24-17(13-34-37(24)21-4-2-20(28)3-5-21)12-26(18,16-36)25(38)23-10-19(6-8-32-23)27(29,30)31/h2-6,8,10-11,13-15H,7,9,12,16H2,1H3/t26-/m0/s1"	"yes"	""	""
"9536"	"relatlimab"	""	"Antibody"	"yes"	""	""	""	"336446922"	""	""	""	""	""	""	""	""	""	"relatlimab"	"BMS-986016|BMS986016|ONO-4482|Opdualag&reg; (nivolumab + relatlimab-rmbw)|relatlimab-rmbw"	""	""	""	"yes"	""	""
"10457"	"remibrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"385612217"	"118107483"	""	""	""	""	""	""	""	"N-[3-[6-amino-5-[2-[methyl(prop-2-enoyl)amino]ethoxy]pyrimidin-4-yl]-5-fluoro-2-methylphenyl]-4-cyclopropyl-2-fluorobenzamide"	"remibrutinib"	"compound 25 [PMID: 32083858]|example 6 [WO2015079417A1]|LOU-064|LOU064|LOU064-NXA|NVP-LOU064-NXA|Rhapsido&reg;"	"C=CC(=O)N(CCOc1c(N)ncnc1c1cc(F)cc(c1C)NC(=O)c1ccc(cc1F)C1CC1)C"	"CUABMPOJOBCXJI-UHFFFAOYSA-N"	"InChI=1S/C27H27F2N5O3/c1-4-23(35)34(3)9-10-37-25-24(31-14-32-26(25)30)20-12-18(28)13-22(15(20)2)33-27(36)19-8-7-17(11-21(19)29)16-5-6-16/h4,7-8,11-14,16H,1,5-6,9-10H2,2-3H3,(H,33,36)(H2,30,31,32)"	"yes"	""	""
"9597"	"remtolumab"	""	"Antibody"	""	""	""	""	"340590227"	""	""	""	""	""	""	""	""	""	"remtolumab"	"A-1230717|ABT-122"	""	""	""	"yes"	""	""
"8498"	"reparixin"	""	"Synthetic organic"	""	""	""	""	"252166706"	"9838712"	""	""	"CHEMBL191413"	""	""	""	""	"(2R)-2-[4-(2-methylpropyl)phenyl]-N-methylsulfonylpropanamide"	"reparixin"	"DF 1681Y|repertaxin"	"CC(Cc1ccc(cc1)[C@H](C(=O)NS(=O)(=O)C)C)C"	"KQDRVXQXKZXMHP-LLVKDONJSA-N"	"InChI=1S/C14H21NO3S/c1-10(2)9-12-5-7-13(8-6-12)11(3)14(16)15-19(4,17)18/h5-8,10-11H,9H2,1-4H3,(H,15,16)/t11-/m1/s1"	"yes"	""	""
"10613"	"reproxalap"	""	"Synthetic organic"	""	""	""	""	"404859060"	"16088030"	""	""	""	""	""	""	""	"2-(3-amino-6-chloroquinolin-2-yl)propan-2-ol"	"reproxalap"	"ADX-102|ADX102|example 5 [WO2018039197A1]|NS-2|NS2"	"Clc1ccc2c(c1)cc(c(n2)C(O)(C)C)N"	"GUHFUVLKYSQIOQ-UHFFFAOYSA-N"	"InChI=1S/C12H13ClN2O/c1-12(2,16)11-9(14)6-7-5-8(13)3-4-10(7)15-11/h3-6,16H,14H2,1-2H3"	"yes"	""	""
"9036"	"resatorvid"	""	"Synthetic organic"	""	""	""	""	"315661121"	"11703255"	""	""	"CHEMBL225157"	""	""	""	""	"ethyl (6R)-6-[(2-chloro-4-fluorophenyl)sulfamoyl]cyclohexene-1-carboxylate"	"resatorvid"	"TAK-242|TAK242"	"CCOC(=O)C1=CCCC[C@H]1S(=O)(=O)Nc1ccc(cc1Cl)F"	"LEEIJTHMHDMWLJ-CQSZACIVSA-N"	"InChI=1S/C15H17ClFNO4S/c1-2-22-15(19)11-5-3-4-6-14(11)23(20,21)18-13-8-7-10(17)9-12(13)16/h5,7-9,14,18H,2-4,6H2,1H3/t14-/m1/s1"	"yes"	""	""
"5051"	"resiquimod"	""	"Synthetic organic"	""	""	""	""	"178101746"	"159603"	""	""	"CHEMBL383322"	""	""	""	""	"1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol"	"resiquimod"	"R-848|R848"	"CCOCc1nc2c(n1CC(O)(C)C)c1ccccc1nc2N"	"BXNMTOQRYBFHNZ-UHFFFAOYSA-N"	"InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)"	"yes"	""	""
"8091"	"reslizumab"	""	"Antibody"	"yes"	""	""	""	"249565771"	""	""	""	""	""	""	""	""	""	"reslizumab"	"CDP-835|CDP835|Cinqaero&reg;|Cinqair&reg;|JES1-39D10|SCH55700"	""	""	""	"yes"	""	""
"3934"	"resolvin D1"	""	"Metabolite"	""	""	""	""	"178100762"	"73755062"	""	""	""	""	""	""	""	"(4Z,7S,8S,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoic acid"	""	"7S,8R,17S‐trihydroxy‐4Z,9E,11E,13Z,15E,19Z‐docosahexaenoic acid|RvD1"	"CC/C=C\C[C@@H](/C=C/C=C\C=C\C=C\[C@@H]([C@H](C/C=C\CCC(=O)O)O)O)O"	"OIWTWACQMDFHJG-LDOXQWQISA-N"	"InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21-/m0/s1"	"yes"	""	""
"5417"	"resolvin D2"	""	"Metabolite"	""	""	""	""	"178102070"	"16061136"	""	""	""	""	""	""	""	"(4Z,7R,8E,10Z,12E,14E,17S,19Z)-7,16,17-trihydroxydocosa-4,8,10,12,14,19-hexaenoic acid"	""	""	"CC/C=C\C[C@@H](C(/C=C/C=C/C=C\C=C\[C@@H](C/C=C\CCC(=O)O)O)O)O"	"IKFAUGXNBOBQDM-GIINMYNKSA-N"	"InChI=1S/C22H32O5/c1-2-3-9-16-20(24)21(25)17-12-7-5-4-6-10-14-19(23)15-11-8-13-18-22(26)27/h3-12,14,17,19-21,23-25H,2,13,15-16,18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,11-8-,14-10+,17-12+/t19-,20-,21?/m0/s1"	"yes"	""	""
"3333"	"resolvin E1"	""	"Metabolite"	""	""	""	""	"178100364"	"10473088"	""	""	"CHEMBL1742483"	""	""	""	""	"(5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid"	""	"5S,12R,18R‐trihydroxy‐6Z,8E,10E,14Z,16E‐eicosapentaenoic acid|RvE1"	"CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O"	"AOPOCGPBAIARAV-OTBJXLELSA-N"	"InChI=1S/C20H30O5/c1-2-17(21)11-8-5-9-14-18(22)12-6-3-4-7-13-19(23)15-10-16-20(24)25/h3-9,11-13,17-19,21-23H,2,10,14-16H2,1H3,(H,24,25)/b4-3+,9-5-,11-8+,12-6+,13-7-/t17-,18+,19-/m1/s1"	"yes"	""	""
"8741"	"resveratrol"	""	"Natural product"	""	""	""	""	"252827399"	"445154"	""	""	"CHEMBL165"	""	""	""	""	"5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol"	"resveratrol"	"3,4',5-stilbenetriol|3,5,4'-trihydroxystilbene|trans-resveratrol"	"Oc1ccc(cc1)/C=C/c1cc(O)cc(c1)O"	"LUKBXSAWLPMMSZ-OWOJBTEDSA-N"	"InChI=1S/C14H12O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9,15-17H/b2-1+"	"yes"	""	""
"11583"	"retifanlimab"	""	"Antibody"	"yes"	""	""	""	"442878617"	""	""	""	""	""	""	""	""	""	"retifanlimab"	"hPD-1 mAb 7(1.2)|INCMGA0012|MGA012|retifanlimab-dlwr|Zynyz&reg;"	""	""	""	"yes"	""	""
"14515"	"retlirafusp alfa"	""	"Antibody"	"yes"	""	""	""	""	""	""	""	""	""	""	""	""	""	"retlirafusp alfa"	"Ezeli&reg; (China)|SHR-1701|SHR1701"	""	""	""	"yes"	""	""
"9865"	"revamilast"	""	"Synthetic organic"	""	""	""	""	"363894159"	"11546664"	""	""	""	""	""	""	""	"N-(3,5-dichloro-1-hydroxypyridin-4-ylidene)-6-(difluoromethoxy)-[1]benzoxolo[3,2-c]pyridine-9-carboxamide"	"revamilast"	"Example 26 [WO2006064355A2]|GRC 4039|GRC-4039|GRC4039"	"FC(Oc1ccc(c2c1oc1c2cncc1)C(=O)N=c1c(Cl)cn(cc1Cl)O)F"	"CFRXVFRHMZLQBS-UHFFFAOYSA-N"	"InChI=1S/C18H9Cl2F2N3O4/c19-10-6-25(27)7-11(20)15(10)24-17(26)8-1-2-13(29-18(21)22)16-14(8)9-5-23-4-3-12(9)28-16/h1-7,18,27H"	"yes"	""	""
"14521"	"rezorstobart"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9599"	"RG7112"	""	"Synthetic organic"	""	""	""	""	"340590229"	"57406853"	""	""	"CHEMBL2386346"	""	""	""	""	"[(4S,5R)-2-(4-tert-butyl-2-ethoxyphenyl)-4,5-bis(4-chlorophenyl)-4,5-dimethylimidazol-1-yl]-[4-(3-methylsulfonylpropyl)piperazin-1-yl]methanone"	""	""	"CCOc1cc(ccc1C1=N[C@@]([C@@](N1C(=O)N1CCN(CC1)CCCS(=O)(=O)C)(C)c1ccc(cc1)Cl)(C)c1ccc(cc1)Cl)C(C)(C)C"	"QBGKPEROWUKSBK-QPPIDDCLSA-N"	"InChI=1S/C38H48Cl2N4O4S/c1-8-48-33-26-29(36(2,3)4)14-19-32(33)34-41-37(5,27-10-15-30(39)16-11-27)38(6,28-12-17-31(40)18-13-28)44(34)35(45)43-23-21-42(22-24-43)20-9-25-49(7,46)47/h10-19,26H,8-9,20-25H2,1-7H3/t37-,38+/m0/s1"	"yes"	""	""
"7376"	"rilapladib"	""	"Synthetic organic"	""	""	""	""	"178103948"	"9918381"	""	""	"CHEMBL2104981"	""	""	""	""	"2-[2-[(2,3-difluorophenyl)methylsulfanyl]-4-oxoquinolin-1-yl]-N-[1-(2-methoxyethyl)piperidin-4-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide"	"rilapladib"	"SB 659032"	"COCCN1CCC(CC1)N(C(=O)Cn1c(SCc2cccc(c2F)F)cc(=O)c2c1cccc2)Cc1ccc(cc1)c1ccc(cc1)C(F)(F)F"	"NNBGCSGCRSCFEA-UHFFFAOYSA-N"	"InChI=1S/C40H38F5N3O3S/c1-51-22-21-46-19-17-32(18-20-46)47(24-27-9-11-28(12-10-27)29-13-15-31(16-14-29)40(43,44)45)37(50)25-48-35-8-3-2-6-33(35)36(49)23-38(48)52-26-30-5-4-7-34(41)39(30)42/h2-16,23,32H,17-22,24-26H2,1H3"	"yes"	""	""
"6790"	"rilonacept"	""	"Peptide"	"yes"	""	""	""	"178103396"	""	""	""	"CHEMBL1201830"	""	""	""	""	""	"rilonacept"	"Arcalyst&reg;|IL-1 Trap|interleukin-1 Trap"	""	""	""	"yes"	""	""
"9993"	"rilzabrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"374883880"	"73388818"	""	""	"CHEMBL3702854"	""	""	""	""	"(E)-2-[(3R)-3-[4-amino-3-(2-fluoro-4-phenoxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pent-2-enenitrile"	"rilzabrutinib"	"Example 31 [WO2014039899]|PRN-1008|PRN1008|Wayrilz&reg;"	"N#C/C(=C\C(N1CCN(CC1)C1COC1)(C)C)/C(=O)N1CCC[C@H](C1)n1nc(c2c1ncnc2N)c1ccc(cc1F)Oc1ccccc1"	"LCFFREMLXLZNHE-GBOLQPHISA-N"	"InChI=1S/C36H40FN9O3/c1-36(2,45-15-13-43(14-16-45)26-21-48-22-26)18-24(19-38)35(47)44-12-6-7-25(20-44)46-34-31(33(39)40-23-41-34)32(42-46)29-11-10-28(17-30(29)37)49-27-8-4-3-5-9-27/h3-5,8-11,17-18,23,25-26H,6-7,12-16,20-22H2,1-2H3,(H2,39,40,41)/b24-18+/t25-/m1/s1"	"yes"	""	""
"9364"	"rimacalib"	""	"Synthetic organic"	""	""	""	""	"328083466"	"9800765"	""	""	"CHEMBL2107772"	""	""	""	""	"N'-[3-[(1S)-1-(3-fluoro-4-phenylphenyl)ethyl]-1,2-oxazol-5-yl]morpholine-4-carboximidamide"	"rimacalib"	"SMP-114"	"N/C(=N\c1onc(c1)[C@H](c1ccc(c(c1)F)c1ccccc1)C)/N1CCOCC1"	"MYTIJGWONQOOLC-HNNXBMFYSA-N"	"InChI=1S/C22H23FN4O2/c1-15(17-7-8-18(19(23)13-17)16-5-3-2-4-6-16)20-14-21(29-26-20)25-22(24)27-9-11-28-12-10-27/h2-8,13-15H,9-12H2,1H3,(H2,24,25)/t15-/m0/s1"	"yes"	""	""
"7099"	"rimexolone"	""	"Metabolite"	"yes"	""	""	""	"178103677"	"5311412"	""	""	"CHEMBL1200617"	""	""	""	""	"(8S,9S,10R,11S,13S,14S,16R,17S)-11-hydroxy-10,13,16,17-tetramethyl-17-propanoyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one"	"rimexolone"	"ORG-6216|Vexol&reg;"	"CCC(=O)[C@@]1(C)[C@H](C)C[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)C=C[C@]12C"	"QTTRZHGPGKRAFB-OOKHYKNYSA-N"	"InChI=1S/C24H34O3/c1-6-20(27)24(5)14(2)11-18-17-8-7-15-12-16(25)9-10-22(15,3)21(17)19(26)13-23(18,24)4/h9-10,12,14,17-19,21,26H,6-8,11,13H2,1-5H3/t14-,17+,18+,19+,21-,22+,23+,24-/m1/s1"	"yes"	""	""
"9643"	"RIPA-56"	""	"Synthetic organic"	""	""	""	""	"340590273"	"121439991"	""	""	""	""	""	""	""	"N-benzyl-N-hydroxy-2,2-dimethylbutanamide"	""	"compound 56 [PMID: 27992216]|compound 92 [WO2016101885]"	"CCC(C(=O)N(Cc1ccccc1)O)(C)C"	"AVYVHIKSFXVDBG-UHFFFAOYSA-N"	"InChI=1S/C13H19NO2/c1-4-13(2,3)12(15)14(16)10-11-8-6-5-7-9-11/h5-9,16H,4,10H2,1-3H3"	"yes"	""	""
"10413"	"RIPK2 inhibitor 3"	""	"Synthetic organic"	""	""	""	""	"385612173"	"73386708"	""	""	""	""	""	""	""	"2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinazolin-7-yl]oxyethyl dihydrogen phosphate"	""	"compound 3 [PMID: 31265286]|Example 1 [WO2014043446A1]|GSK2983559"	"OP(=O)(OCCOc1cc2ncnc(c2cc1S(=O)(=O)C(C)(C)C)Nc1ccc2c(c1)ncs2)O"	"MJLYDVMFNHZMLV-UHFFFAOYSA-N"	"InChI=1S/C21H23N4O7PS2/c1-21(2,3)35(29,30)19-9-14-15(10-17(19)31-6-7-32-33(26,27)28)22-11-23-20(14)25-13-4-5-18-16(8-13)24-12-34-18/h4-5,8-12H,6-7H2,1-3H3,(H,22,23,25)(H2,26,27,28)"	"yes"	""	""
"10419"	"RIPK2 inhibitor 5"	""	"Synthetic organic"	""	""	""	""	"385612179"	"71258526"	""	""	""	""	""	""	""	"2-[4-(1,3-benzothiazol-5-ylamino)-6-tert-butylsulfonylquinazolin-7-yl]oxyethanol"	""	"compound 5 [PMID: 31265286]"	"OCCOc1cc2ncnc(c2cc1S(=O)(=O)C(C)(C)C)Nc1ccc2c(c1)ncs2"	"UHDOJINBFLDQJM-UHFFFAOYSA-N"	"InChI=1S/C21H22N4O4S2/c1-21(2,3)31(27,28)19-9-14-15(10-17(19)29-7-6-26)22-11-23-20(14)25-13-4-5-18-16(8-13)24-12-30-18/h4-5,8-12,26H,6-7H2,1-3H3,(H,22,23,25)"	"yes"	""	""
"9688"	"RIPK2 inhibitor 8"	""	"Synthetic organic"	""	""	""	""	"348353647"	"131801159"	""	""	""	""	""	""	""	"4-[7-ethoxy-6-(2-methylpropane-2-sulfonyl)imidazo[1,2-a]pyridin-3-yl]-6-fluoropyridin-2-amine"	""	""	"CCOc1cc2ncc(n2cc1S(=O)(=O)C(C)(C)C)c1cc(N)nc(c1)F"	"QWDMZDSZMVJFFJ-UHFFFAOYSA-N"	"InChI=1S/C18H21FN4O3S/c1-5-26-13-8-17-21-9-12(11-6-15(19)22-16(20)7-11)23(17)10-14(13)27(24,25)18(2,3)4/h6-10H,5H2,1-4H3,(H2,20,22)"	"yes"	""	""
"10389"	"RIPK3 inhibitor 18"	""	"Synthetic organic"	""	""	""	""	"384403668"	"138393291"	""	""	""	""	""	""	""	"N-{4-[(2-cyclopropaneamidopyridin-4-yl)oxy]-2,3-dimethylphenyl}-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide"	""	""	"O=C(C1CC1)Nc1nccc(c1)Oc1ccc(c(c1C)C)NC(=O)c1cccn(c1=O)c1ccc(cc1)F"	"PETCZXAONWLUFT-UHFFFAOYSA-N"	"InChI=1S/C29H25FN4O4/c1-17-18(2)25(38-22-13-14-31-26(16-22)33-27(35)19-5-6-19)12-11-24(17)32-28(36)23-4-3-15-34(29(23)37)21-9-7-20(30)8-10-21/h3-4,7-16,19H,5-6H2,1-2H3,(H,32,36)(H,31,33,35)"	"yes"	""	""
"10401"	"RIPK3 inhibitor 42"	""	"Synthetic organic"	""	""	""	""	"384403680"	"138393293"	""	""	""	""	""	""	""	"N-(6-(3-(3-(3-Bromophenyl)ureido)-4-fluorophenoxy)benzo[d]thiazol-2-yl)cyclopropanecarboxamide"	""	""	"O=C(Nc1cc(ccc1F)Oc1ccc2c(c1)sc(n2)NC(=O)C1CC1)Nc1cccc(c1)Br"	"RIVQMLWSKYAVFY-UHFFFAOYSA-N"	"InChI=1S/C24H18BrFN4O3S/c25-14-2-1-3-15(10-14)27-23(32)28-20-11-16(6-8-18(20)26)33-17-7-9-19-21(12-17)34-24(29-19)30-22(31)13-4-5-13/h1-3,6-13H,4-5H2,(H2,27,28,32)(H,29,30,31)"	"yes"	""	""
"8922"	"risankizumab"	""	"Antibody"	"yes"	""	""	""	"310264703"	""	""	""	""	""	""	""	""	""	"risankizumab"	"ABBV-066|BI 655066|BI-655066|risankizumab-rzaa|Skyrizi&reg;"	""	""	""	"yes"	""	""
"9559"	"ritlecitinib"	""	"Synthetic organic"	"yes"	""	""	""	"336446945"	"118115473"	""	""	""	""	""	""	""	"1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one"	"ritlecitinib"	"compound 11 [PMID: 28139931]|example 5 [WO2015083028]|Litfulo&reg;|PF-06651600|PF06651600"	"C=CC(=O)N1C[C@@H](CC[C@@H]1C)Nc1ncnc2c1cc[nH]2"	"CBRJPFGIXUFMTM-WDEREUQCSA-N"	"InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1"	"yes"	""	""
"6780"	"rituximab"	""	"Antibody"	"yes"	""	""	""	"178103386"	""	""	""	""	""	""	""	""	""	"rituximab"	"HSDB 7455|IDEC-C2B8|MabThera&reg;|Rituxan&reg;"	""	""	""	"yes"	""	""
"5052"	"Ro26-4550"	""	"Synthetic organic"	""	""	""	""	"178101747"	"73755110"	""	""	""	""	""	""	""	"methyl (2S)-2-{2-[(3R)-1-methanehydrazonoylpiperidin-3-yl]acetamido}-3-[4-(2-phenylethynyl)phenyl]propanoate"	""	"Ro 26-4550|Ro-26-4550"	"NN=CN1CCC[C@@H](C1)CC(=O)N[C@H](C(=O)OC)Cc1ccc(cc1)C#Cc1ccccc1"	"YQDXLNDLKSCQKX-RPWUZVMVSA-N"	"InChI=1S/C26H30N4O3/c1-33-26(32)24(29-25(31)17-23-8-5-15-30(18-23)19-28-27)16-22-13-11-21(12-14-22)10-9-20-6-3-2-4-7-20/h2-4,6-7,11-14,19,23-24H,5,8,15-18,27H2,1H3,(H,29,31)/t23-,24+/m1/s1"	"yes"	""	""
"13045"	"rocatinlimab"	""	"Antibody"	""	""	""	""	"491299827"	""	""	""	""	""	""	""	""	""	"rocatinlimab"	"AMG-451|AMG451|KHK-4083|KHK4083"	""	""	""	"yes"	""	""
"12875"	"rocbrutinib"	""	"Synthetic organic"	""	""	""	""	"485205996"	"139416847"	""	""	""	""	""	""	""	""	""	""	"[H][C@]1(C)CN(CCN1C2=CC=C(NC3=NC(=CN(C)C3=O)C4=C(CO)C(=NC=C4)N5CCN6C7=C(CC(C)(C)C7)C=C6C5=O)C=C2NC(=O)C=C)C8CCOCC8"	"OYJVFTNYBWVQHA-SANMLTNESA-N"	"InChI=1S/C42H51N9O5/c1-6-37(53)45-32-20-28(7-8-34(32)49-14-13-48(23-26(49)2)29-10-17-56-18-11-29)44-38-41(55)47(5)24-33(46-38)30-9-12-43-39(31(30)25-52)51-16-15-50-35(40(51)54)19-27-21-42(3,4)22-36(27)50/h6-9,12,19-20,24,26,29,52H,1,10-11,13-18,21-23,25H2,2-5H3,(H,44,46)(H,45,53)/t26-/m0/s1"	"yes"	""	""
"2893"	"rofecoxib"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178100242"	"5090"	""	""	"CHEMBL122"	""	""	""	""	"4-(4-methylsulfonylphenyl)-3-phenyl-5H-furan-2-one"	"rofecoxib"	"Ceoxx&reg;|MK 966|Vioxx&reg;"	"O=C1OCC(=C1c1ccccc1)c1ccc(cc1)S(=O)(=O)C"	"RZJQGNCSTQAWON-UHFFFAOYSA-N"	"InChI=1S/C17H14O4S/c1-22(19,20)14-9-7-12(8-10-14)15-11-21-17(18)16(15)13-5-3-2-4-6-13/h2-10H,11H2,1H3"	"yes"	""	""
"6962"	"roflumilast"	""	"Synthetic organic"	"yes"	""	""	""	"178103543"	"449193"	""	""	"CHEMBL193240"	""	""	""	""	"3-(CYCLOPROPYLMETHOXY)-N-(3,5-DICHLOROPYRIDIN-4-YL)-4-(DIFLUOROMETHOXY)BENZAMIDE"	"roflumilast"	"ARQ-151/Zoryve&reg; (roflumilast cream)|BY-217|BYK-20869|Daliresp&reg;|Daxas&reg;"	"FC(Oc1ccc(cc1OCC1CC1)C(=O)Nc1c(Cl)cncc1Cl)F"	"MNDBXUUTURYVHR-UHFFFAOYSA-N"	"InChI=1S/C17H14Cl2F2N2O3/c18-11-6-22-7-12(19)15(11)23-16(24)10-3-4-13(26-17(20)21)14(5-10)25-8-9-1-2-9/h3-7,9,17H,1-2,8H2,(H,22,23,24)"	"yes"	""	""
"10691"	"roflupram"	""	"Synthetic organic"	""	""	""	""	"404859138"	"25147798"	""	""	""	""	""	""	""	"1-[4-(difluoromethoxy)-3-(oxolan-3-yloxy)phenyl]-3-methylbutan-1-one"	""	"FFPM|Zl-n-91"	"CC(CC(=O)c1ccc(c(c1)OC1COCC1)OC(F)F)C"	"IXURVUHDDXFYDR-UHFFFAOYSA-N"	"InChI=1S/C16H20F2O4/c1-10(2)7-13(19)11-3-4-14(22-16(17)18)15(8-11)21-12-5-6-20-9-12/h3-4,8,10,12,16H,5-7,9H2,1-2H3"	"yes"	""	""
"5260"	"rolipram"	""	"Synthetic organic"	""	""	""	""	"178101944"	"5092"	""	""	"CHEMBL63"	""	""	""	""	"4-[3-(cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one"	"rolipram"	"(&plusmn;)-rolipram|(R,S)-rolipram"	"COc1ccc(cc1OC1CCCC1)C1CNC(=O)C1"	"HJORMJIFDVBMOB-UHFFFAOYSA-N"	"InChI=1S/C16H21NO3/c1-19-14-7-6-11(12-9-16(18)17-10-12)8-15(14)20-13-4-2-3-5-13/h6-8,12-13H,2-5,9-10H2,1H3,(H,17,18)"	"yes"	""	""
"6625"	"ROMe"	""	"Synthetic organic"	""	""	""	""	"178103238"	"71458556"	""	""	"CHEMBL2158686"	""	""	""	""	"(2R)-2-amino-2-(methoxymethyl)-4-(4-octylphenyl)butan-1-ol"	""	"(<i>R</i>)-FTY720 methyl ether|(<i>R</i>)-FTY720-OMe"	"CCCCCCCCc1ccc(cc1)CC[C@](COC)(CO)N"	"YEYZALQTJCVXIJ-HXUWFJFHSA-N"	"InChI=1S/C20H35NO2/c1-3-4-5-6-7-8-9-18-10-12-19(13-11-18)14-15-20(21,16-22)17-23-2/h10-13,22H,3-9,14-17,21H2,1-2H3/t20-/m1/s1"	"yes"	""	""
"6974"	"romiplostim"	""	"Peptide"	"yes"	""	""	""	"178103553"	""	""	""	"CHEMBL1201832"	""	""	""	""	""	"romiplostim"	"MG531|Nplate&reg;"	""	""	""	"yes"	""	""
"9640"	"rontalizumab"	""	"Antibody"	""	""	""	""	"340590270"	""	""	""	""	""	""	""	""	""	"rontalizumab"	"9F3v13|RhuMAB IFNalpha|rhuMAb interferon-&alpha;"	""	""	""	"yes"	""	""
"10078"	"RORC2 inverse agonist 66 [PMID: 30130103]"	""	"Synthetic organic"	""	""	""	""	"375973265"	"118977746"	""	""	""	""	""	""	""	"3-cyano-N-[1-methyl-3-[1-(2-methylpropanoyl)piperidin-4-yl]-4-(trifluoromethyl)pyrrolo[2,3-b]pyridin-5-yl]benzamide"	""	"example 5 [WO2016046755A1]"	"N#Cc1cccc(c1)C(=O)Nc1cnc2c(c1C(F)(F)F)c(cn2C)C1CCN(CC1)C(=O)C(C)C"	"BIHPJIJLDNUDGH-UHFFFAOYSA-N"	"InChI=1S/C26H26F3N5O2/c1-15(2)25(36)34-9-7-17(8-10-34)19-14-33(3)23-21(19)22(26(27,28)29)20(13-31-23)32-24(35)18-6-4-5-16(11-18)12-30/h4-6,11,13-15,17H,7-10H2,1-3H3,(H,32,35)"	"yes"	""	""
"9249"	"rosiptor"	""	"Synthetic organic"	""	""	""	""	"315661324"	"76965484"	""	""	""	""	""	""	""	"(1S,3S,4R)-4-[(3aS,4R,5S,7aS)-4-(aminomethyl)-7a-methyl-1-methylidene-3,3a,4,5,6,7-hexahydro-2H-inden-5-yl]-3-(hydroxymethyl)-4-methylcyclohexan-1-ol"	"rosiptor"	"AQX-1125|AQX1125"	"NC[C@@H]1[C@H](CC[C@]2([C@H]1CCC2=C)C)[C@@]1(C)CC[C@@H](C[C@@H]1CO)O"	"MDEJTPWQNNMAQF-BVMLLJBZSA-N"	"InChI=1S/C20H35NO2/c1-13-4-5-17-16(11-21)18(7-9-19(13,17)2)20(3)8-6-15(23)10-14(20)12-22/h14-18,22-23H,1,4-12,21H2,2-3H3/t14-,15+,16+,17+,18+,19-,20+/m1/s1"	"yes"	""	""
"14271"	"rosnilimab"	""	"Antibody"	""	""	""	""	"521588911"	""	""	""	""	""	""	""	""	""	"rosnilimab"	"ANB-030|ANB030"	""	""	""	"yes"	""	""
"9625"	"rovazolac"	""	"Synthetic organic"	""	""	""	""	"340590255"	"89792952"	""	""	""	""	""	""	""	"ethyl 2-[5-[4-(3-methylsulfonylphenyl)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]acetate"	"rovazolac"	"A-110|ALX-101|example 36 [WO2013130892]"	"CCOC(=O)Cn1nc(cc1c1ccc(cc1)c1cccc(c1)S(=O)(=O)C)C(F)(F)F"	"ZUMNJDGBYXHASJ-UHFFFAOYSA-N"	"InChI=1S/C21H19F3N2O4S/c1-3-30-20(27)13-26-18(12-19(25-26)21(22,23)24)15-9-7-14(8-10-15)16-5-4-6-17(11-16)31(2,28)29/h4-12H,3,13H2,1-2H3"	"yes"	""	""
"9598"	"rovelizumab"	""	"Antibody"	""	""	""	""	"340590228"	""	""	""	""	""	""	""	""	""	"rovelizumab"	"Hu23F2G|LeukArrest"	""	""	""	"yes"	""	""
"9801"	"rozanolixizumab"	""	"Antibody"	"yes"	""	""	""	"354702273"	""	""	""	""	""	""	""	""	""	"rozanolixizumab"	"CA170_01519.g57 IgG4P|rozanolixizumab-noli|Rystiggo&reg;|UCB-7665|UCB7665"	""	""	""	"yes"	""	""
"9889"	"RP-101075"	""	"Synthetic organic"	""	""	""	""	"363894183"	"52938426"	""	""	""	""	""	""	""	""	""	""	"N#Cc1cc(ccc1OC(C)C)c1onc(n1)c1cccc2c1CC[C@@H]2N"	"WGUXQKIWMYYPQI-SFHVURJKSA-N"	"InChI=1S/C21H20N4O2/c1-12(2)26-19-9-6-13(10-14(19)11-22)21-24-20(25-27-21)17-5-3-4-16-15(17)7-8-18(16)23/h3-6,9-10,12,18H,7-8,23H2,1-2H3/t18-/m0/s1"	"yes"	""	""
"779"	"RS-102895"	""	"Synthetic organic"	""	""	""	""	"135650935"	"10000456"	""	""	"CHEMBL1593104"	""	""	""	""	"1'-[2-[4-(trifluoromethyl)phenyl]ethyl]spiro[1H-3,1-benzoxazine-4,4'-piperidine]-2-one"	""	"abaucin|RS102895"	"O=C1Nc2ccccc2C2(O1)CCN(CC2)CCc1ccc(cc1)C(F)(F)F"	"HIDWEYPGMLIQSN-UHFFFAOYSA-N"	"InChI=1S/C21H21F3N2O2/c22-21(23,24)16-7-5-15(6-8-16)9-12-26-13-10-20(11-14-26)17-3-1-2-4-18(17)25-19(27)28-20/h1-8H,9-14H2,(H,25,27)"	"yes"	""	"yes"
"781"	"RS-504393"	""	"Synthetic organic"	""	""	""	""	"135650944"	"9953769"	""	""	"CHEMBL134074"	""	""	""	""	"6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]-1,2-dihydrospiro[3,1-benzoxazine-4,4'-piperidine]-2-one"	""	"RS 504393|RS504393"	"O=C1Nc2ccc(cc2C2(O1)CCN(CC2)CCc1nc(oc1C)c1ccccc1)C"	"ODNICNWASXKNNQ-UHFFFAOYSA-N"	"InChI=1S/C25H27N3O3/c1-17-8-9-22-20(16-17)25(31-24(29)27-22)11-14-28(15-12-25)13-10-21-18(2)30-23(26-21)19-6-4-3-5-7-19/h3-9,16H,10-15H2,1-2H3,(H,27,29)"	"yes"	""	""
"10412"	"RSLV-132"	""	"Peptide"	""	""	""	""	"387271629"	""	""	""	""	""	""	""	""	""	""	"RSLV132"	""	""	""	"yes"	""	""
"12006"	"(R)-STU104"	""	"Synthetic organic"	""	""	""	""	"464244147"	"156579934"	""	""	""	""	""	""	""	"(3R)-4,6-dimethoxy-3-(4-methoxyphenyl)-2,3-dihydroinden-1-one"	""	"(R)-4e [PMID: 35442672]"	"O=C1C[C@H](c2ccc(OC)cc2)c2c(OC)cc(OC)cc12"	"OYJBHGSSAJNKJF-CQSZACIVSA-N"	"InChI=1S/C18H18O4/c1-20-12-6-4-11(5-7-12)14-10-16(19)15-8-13(21-2)9-17(22-3)18(14)15/h4-9,14H,10H2,1-3H3/t14-/m1/s1"	"yes"	""	""
"10103"	"rupatadine"	""	"Synthetic organic"	"yes"	""	""	""	"381118813"	"133017"	""	""	"CHEMBL91397"	""	""	""	""	"8-chloro-11-[1-[(5-methylpyridin-3-yl)methyl]piperidin-4-ylidene]-5,6-dihydrobenzo[1,2]cyclohepta[2,4-b]pyridine"	"rupatadine"	"Rinialer&reg;|Rupafin&reg;|UR-12592|UR12592"	"Cc1cncc(c1)CN1CCC(=C2c3ccc(cc3CCc3c2nccc3)Cl)CC1"	"WUZYKBABMWJHDL-UHFFFAOYSA-N"	"InChI=1S/C26H26ClN3/c1-18-13-19(16-28-15-18)17-30-11-8-20(9-12-30)25-24-7-6-23(27)14-22(24)5-4-21-3-2-10-29-26(21)25/h2-3,6-7,10,13-16H,4-5,8-9,11-12,17H2,1H3"	"yes"	""	""
"5688"	"ruxolitinib"	""	"Synthetic organic"	"yes"	""	""	""	"178102315"	"25126798"	""	""	"CHEMBL1789941"	""	""	""	""	"(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyrimidin-4-yl}-1H-pyrazol-1-yl)propanenitrile"	"ruxolitinib"	"<i>(R)</i>-ruxolitinib|INC424|INCB 18424|INCB018424|Jakafi&reg;|Jakavi&reg;"	"N#CC[C@@H](n1ncc(c1)c1ncnc2c1cc[nH]2)C1CCCC1"	"HFNKQEVNSGCOJV-OAHLLOKOSA-N"	"InChI=1S/C17H18N6/c18-7-5-15(12-3-1-2-4-12)23-10-13(9-22-23)16-14-6-8-19-17(14)21-11-20-16/h6,8-12,15H,1-5H2,(H,19,20,21)/t15-/m1/s1"	"yes"	""	""
"10162"	"RV1729"	""	"Synthetic organic"	""	""	""	""	"381118872"	"52913198"	""	""	"CHEMBL3919512"	""	""	""	""	"6-[2-[[4-amino-3-(3-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-3-[(2-chlorophenyl)methyl]-4-oxoquinazolin-5-yl]-N,N-bis(2-methoxyethyl)hex-5-ynamide"	""	"RV-1729"	"COCCN(C(=O)CCCC#Cc1cccc2c1c(=O)n(c(n2)Cn1nc(c2c1ncnc2N)c1cccc(c1)O)Cc1ccccc1Cl)CCOC"	"UBLOHCIYTDRGJH-UHFFFAOYSA-N"	"InChI=1S/C39H39ClN8O5/c1-52-20-18-46(19-21-53-2)33(50)17-5-3-4-10-26-12-9-16-31-34(26)39(51)47(23-28-11-6-7-15-30(28)40)32(44-31)24-48-38-35(37(41)42-25-43-38)36(45-48)27-13-8-14-29(49)22-27/h6-9,11-16,22,25,49H,3,5,17-21,23-24H2,1-2H3,(H2,41,42,43)"	"yes"	""	""
"10163"	"RV6153"	""	"Synthetic organic"	""	""	""	""	"381118873"	"86268622"	""	""	"CHEMBL3934989"	""	""	""	""	"2-[[4-amino-3-(3-fluoro-5-hydroxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-5-[3-[2-(2-methoxyethoxy)ethoxy]prop-1-ynyl]-3-[[2-(trifluoromethyl)phenyl]methyl]quinazolin-4-one"	""	"RV-6153"	"COCCOCCOCC#Cc1cccc2c1c(=O)n(c(n2)Cn1nc(c2c1ncnc2N)c1cc(O)cc(c1)F)Cc1ccccc1C(F)(F)F"	"JTACVHJPXOKMTI-UHFFFAOYSA-N"	"InChI=1S/C36H31F4N7O5/c1-50-12-13-52-15-14-51-11-5-8-22-7-4-10-28-30(22)35(49)46(19-23-6-2-3-9-27(23)36(38,39)40)29(44-28)20-47-34-31(33(41)42-21-43-34)32(45-47)24-16-25(37)18-26(48)17-24/h2-4,6-7,9-10,16-18,21,48H,11-15,19-20H2,1H3,(H2,41,42,43)"	"yes"	""	""
"5555"	"RvD1-ME"	""	"Metabolite"	""	""	""	""	"178102196"	"71519431"	""	""	""	""	""	""	""	"methyl (4Z,7S,8R,9E,11E,13Z,15E,17S,19Z)-7,8,17-trihydroxydocosa-4,9,11,13,15,19-hexaenoate"	""	"RvD1-methyl ester"	"CC/C=C\C[C@@H](/C=C/C=C\C=C\C=C\[C@H]([C@H](C/C=C\CCC(=O)OC)O)O)O"	"WUKVAFWBFGABJN-ZXQGQRHTSA-N"	"InChI=1S/C23H34O5/c1-3-4-10-15-20(24)16-11-7-5-6-8-12-17-21(25)22(26)18-13-9-14-19-23(27)28-2/h4-13,16-17,20-22,24-26H,3,14-15,18-19H2,1-2H3/b7-5-,8-6+,10-4-,13-9-,16-11+,17-12+/t20-,21+,22-/m0/s1"	"yes"	""	""
"9333"	"RWJ-56423"	""	"Synthetic organic"	""	""	""	""	"318164852"	"5287596"	""	""	"CHEMBL256892"	""	""	""	""	"(2S,4R)-1-acetyl-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-hydroxypyrrolidine-2-carboxamide"	""	"(2S)-<b>6</b>"	"NC(=N)NCCC[C@@H](C(=O)c1nc2c(s1)cccc2)NC(=O)[C@@H]1C[C@H](CN1C(=O)C)O"	"VXDAVYUFYPFGDX-SNPRPXQTSA-N"	"InChI=1S/C20H26N6O4S/c1-11(27)26-10-12(28)9-15(26)18(30)24-14(6-4-8-23-20(21)22)17(29)19-25-13-5-2-3-7-16(13)31-19/h2-3,5,7,12,14-15,28H,4,6,8-10H2,1H3,(H,24,30)(H4,21,22,23)/t12-,14+,15+/m1/s1"	"yes"	""	""
"9566"	"(R)-ZINC-3573"	""	"Synthetic organic"	""	""	""	""	"336446952"	"95882507"	""	""	""	""	""	""	""	"(3R)-N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)pyrrolidin-3-amine"	""	"ZINC-72453573"	"CN([C@@H]1CCN(C1)c1cc(nc2n1ncc2)c1ccccc1)C"	"XKBSPAZCFAIBJL-OAHLLOKOSA-N"	"InChI=1S/C18H21N5/c1-21(2)15-9-11-22(13-15)18-12-16(14-6-4-3-5-7-14)20-17-8-10-19-23(17)18/h3-8,10,12,15H,9,11,13H2,1-2H3/t15-/m1/s1"	"yes"	""	""
"12979"	"S-26d [PMID: 37883692]"	""	"Synthetic organic"	""	""	""	""	"485206100"	"169422750"	""	""	""	""	""	""	""	"(3S)-3-[4-({1-cyclopentyl-3-[3,5-dichloro-4-(hydroxymethyl)phenyl]-4-fluoro-1H-indazol-6-yl}methoxy)phenyl]butanoic acid"	""	""	"C[C@@H](CC(O)=O)C1=CC=C(OCC2=CC3=C(C(=NN3C4CCCC4)C5=CC(Cl)=C(CO)C(Cl)=C5)C(F)=C2)C=C1"	"PSFVPDVRKIFGLA-KRWDZBQOSA-N"	"InChI=1S/C30H29Cl2FN2O4/c1-17(10-28(37)38)19-6-8-22(9-7-19)39-16-18-11-26(33)29-27(12-18)35(21-4-2-3-5-21)34-30(29)20-13-24(31)23(15-36)25(32)14-20/h6-9,11-14,17,21,36H,2-5,10,15-16H2,1H3,(H,37,38)/t17-/m0/s1"	"yes"	""	""
"12321"	"S4-1"	""	"Synthetic organic"	""	""	""	""	"479821112"	"166642489"	""	""	""	""	""	""	""	"((6-Methoxy-2-(2-methyl-[1,1′-biphenyl]-3-yl)-1,3-dioxoisoindolin-5-yl)methyl)serine"	""	""	"OC[C@@H](C(=O)O)NCc1cc2c(C(=O)N(c3c(C)c(c4ccccc4)ccc3)C2=O)cc1OC"	"CUQPAAUFONWYPW-NRFANRHFSA-N"	"InChI=1S/C26H24N2O6/c1-15-18(16-7-4-3-5-8-16)9-6-10-22(15)28-24(30)19-11-17(13-27-21(14-29)26(32)33)23(34-2)12-20(19)25(28)31/h3-12,21,27,29H,13-14H2,1-2H3,(H,32,33)/t21-/m0/s1"	"yes"	""	""
"558"	"salbutamol"	""	"Synthetic organic"	"yes"	""	""	""	"135650977"	"2083"	""	""	"CHEMBL714"	""	""	""	""	"4-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)phenol"	"salbutamol"	"albuterol|SCH-13949W|Ventolin&reg;"	"OCc1cc(ccc1O)C(CNC(C)(C)C)O"	"NDAUXUAQIAJITI-UHFFFAOYSA-N"	"InChI=1S/C13H21NO3/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15/h4-6,12,14-17H,7-8H2,1-3H3"	"yes"	""	""
"4306"	"salicylic acid"	""	"Natural product"	"yes"	""	""	""	"178101123"	"338"	""	""	"CHEMBL424"	""	""	""	""	"2-hydroxybenzoic acid"	""	"Bazuka Extra Strength Gel&reg;|salicylate"	"OC(=O)c1ccccc1O"	"YGSDEFSMJLZEOE-UHFFFAOYSA-N"	"InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)"	"yes"	""	""
"559"	"salmeterol"	""	"Synthetic organic"	"yes"	""	""	""	"135650978"	"5152"	""	""	"CHEMBL1263"	""	""	""	""	"2-(hydroxymethyl)-4-[1-hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl]phenol"	"salmeterol"	"GR 33343X|Serevent&reg;"	"OCc1cc(ccc1O)C(CNCCCCCCOCCCCc1ccccc1)O"	"GIIZNNXWQWCKIB-UHFFFAOYSA-N"	"InChI=1S/C25H37NO4/c27-20-23-18-22(13-14-24(23)28)25(29)19-26-15-7-1-2-8-16-30-17-9-6-12-21-10-4-3-5-11-21/h3-5,10-11,13-14,18,25-29H,1-2,6-9,12,15-17,19-20H2"	"yes"	""	""
"13093"	"salvianolic acid A"	""	"Natural product"	""	""	""	""	"491299875"	"5281793"	""	""	"CHEMBL457077"	""	""	""	""	"(2R)-3-(3,4-dihydroxyphenyl)-2-[(E)-3-[2-[(E)-2-(3,4-dihydroxyphenyl)ethenyl]-3,4-dihydroxyphenyl]prop-2-enoyl]oxypropanoic acid"	""	"Dan Phenolic Acid A|Danshen|Sal A"	"C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C/2=C(\C(=C(C=C2)O)O)/C=C/C3=CC(=C(C=C3)O)O)O)O"	"YMGFTDKNIWPMGF-UCPJVGPRSA-N"	"InChI=1S/C26H22O10/c27-18-7-2-14(11-21(18)30)1-6-17-16(4-9-20(29)25(17)33)5-10-24(32)36-23(26(34)35)13-15-3-8-19(28)22(31)12-15/h1-12,23,27-31,33H,13H2,(H,34,35)/b6-1+,10-5+/t23-/m1/s1"	"yes"	""	""
"13067"	"Sanofi-14h"	""	"Synthetic organic"	""	""	""	""	"491299849"	"71537261"	""	""	"CHEMBL3092461"	""	""	""	""	"N-[4-(3-amino-2H-pyrazolo[3,4-b]pyrazin-6-yl)phenyl]-2,5-dichlorobenzenesulfonamide"	""	"compound 14h [PMID: 25589934]"	"NC1=NNC2=C1N=CC(=N2)C3=CC=C(NS(=O)(=O)C4=CC(Cl)=CC=C4Cl)C=C3"	"RTERCHJCWXQPSS-UHFFFAOYSA-N"	"InChI=1S/C17H12Cl2N6O2S/c18-10-3-6-12(19)14(7-10)28(26,27)25-11-4-1-9(2-5-11)13-8-21-15-16(20)23-24-17(15)22-13/h1-8,25H,(H3,20,22,23,24)"	"yes"	""	""
"5276"	"sapropterin"	""	"Metabolite"	"yes"	""	""	""	"178101959"	"135398654"	""	""	"CHEMBL1201774"	""	""	""	""	"(6R)-2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-3,4,5,6,7,8-hexahydropteridin-4-one"	"sapropterin"	"Kuvan&reg;|sapropterin dihydrochloride|SUN-0588|T-1401|tetrahydrobiopterin (THB)"	"C[C@@H]([C@@H]([C@H]1CNc2c(N1)c(=O)[nH]c(n2)N)O)O"	"FNKQXYHWGSIFBK-RPDRRWSUSA-N"	"InChI=1S/C9H15N5O3/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17)/t3-,4+,6-/m0/s1"	"yes"	""	""
"9803"	"SAR-20347"	""	"Synthetic organic"	""	""	""	""	"354702275"	"71727668"	""	""	""	""	""	""	""	""	""	""	"O=C(c1ccc(cc1)Nc1oc(nc1C(=O)N)c1c(F)cccc1Cl)N1CCOCC1"	"HEDPDFHTQKEORT-UHFFFAOYSA-N"	"InChI=1S/C21H18ClFN4O4/c22-14-2-1-3-15(23)16(14)19-26-17(18(24)28)20(31-19)25-13-6-4-12(5-7-13)21(29)27-8-10-30-11-9-27/h1-7,25H,8-11H2,(H2,24,28)"	"yes"	""	""
"7999"	"sarilumab"	""	"Antibody"	"yes"	""	""	""	"249565679"	""	""	""	""	""	""	""	""	""	"sarilumab"	"Kevzara&reg;|REGN88|SAR153191"	""	""	""	"yes"	""	""
"9093"	"satralizumab"	""	"Antibody"	"yes"	""	""	""	"315661178"	""	""	""	""	""	""	""	""	""	"satralizumab"	"Enspryng&reg;|RG-6168|RG6168|SA-237|SA237|sapelizumab (deprecated INN)|satralizumab-mwge"	""	""	""	"yes"	""	""
"4307"	"SB202190"	""	"Synthetic organic"	""	""	""	""	"178101124"	"5169"	""	""	"CHEMBL278041"	""	""	""	""	"4-[5-(4-fluorophenyl)-4-(pyridin-4-yl)-1H-imidazol-2-yl]phenol"	""	"SB 202190|SB-202190"	"Oc1ccc(cc1)c1nc(c([nH]1)c1ccc(cc1)F)c1ccncc1"	"QHKYPYXTTXKZST-UHFFFAOYSA-N"	"InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24)"	"yes"	""	""
"5269"	"SB203580"	""	"Synthetic organic"	""	""	""	""	"178101952"	"176155"	""	""	"CHEMBL10"	""	""	""	""	"4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine"	""	"PB 203580|RWJ 64809|SB-203580"	"Fc1ccc(cc1)c1nc([nH]c1c1ccncc1)c1ccc(cc1)S(=O)C"	"CDMGBJANTYXAIV-UHFFFAOYSA-N"	"InChI=1S/C21H16FN3OS/c1-27(26)18-8-4-16(5-9-18)21-24-19(14-2-6-17(22)7-3-14)20(25-21)15-10-12-23-13-11-15/h2-13H,1H3,(H,24,25)"	"yes"	""	""
"833"	"SB 225002"	""	"Synthetic organic"	""	""	""	""	"135650994"	"3854666"	""	""	"CHEMBL239767"	""	""	""	""	"3-(2-bromophenyl)-1-(2-hydroxy-4-nitrophenyl)urea"	""	"SB-225002|SB225002"	"O=C(Nc1ccccc1Br)Nc1ccc(cc1O)[N+](=O)[O-]"	"MQBZVUNNWUIPMK-UHFFFAOYSA-N"	"InChI=1S/C13H10BrN3O4/c14-9-3-1-2-4-10(9)15-13(19)16-11-6-5-8(17(20)21)7-12(11)18/h1-7,18H,(H2,15,16,19)"	"yes"	""	""
"3529"	"SB290157"	""	"Synthetic organic"	""	""	""	""	"178100508"	"5311120"	""	""	"CHEMBL389348"	""	""	""	""	"(2S)-5-(diaminomethylideneamino)-2-[[2-[2,2-di(phenyl)ethoxy]acetyl]amino]pentanoic acid"	""	"SB-290157"	"O=C(N[C@H](C(=O)O)CCCN=C(N)N)COCC(c1ccccc1)c1ccccc1"	"RRKKJYBCPXAJAO-IBGZPJMESA-N"	"InChI=1S/C22H28N4O4/c23-22(24)25-13-7-12-19(21(28)29)26-20(27)15-30-14-18(16-8-3-1-4-9-16)17-10-5-2-6-11-17/h1-6,8-11,18-19H,7,12-15H2,(H,26,27)(H,28,29)(H4,23,24,25)/t19-/m0/s1"	"yes"	""	""
"3530"	"SB328437"	""	"Synthetic organic"	""	""	""	""	"178100509"	"5311092"	""	""	""	""	""	""	""	"methyl (2S)-2-(naphthalene-2-carbonylamino)-3-(4-nitrophenyl)propanoate"	""	"SB 328437|SB-328437"	"COC(=O)[C@@H](NC(=O)c1ccc2c(c1)cccc2)Cc1ccc(cc1)N(=O)=O"	"KOLBWAVLYDRUOC-IBGZPJMESA-N"	"InChI=1S/C21H18N2O5/c1-28-21(25)19(12-14-6-10-18(11-7-14)23(26)27)22-20(24)17-9-8-15-4-2-3-5-16(15)13-17/h2-11,13,19H,12H2,1H3,(H,22,24)/t19-/m0/s1"	"yes"	""	""
"1923"	"SC-51089"	""	"Synthetic organic"	""	""	""	""	"135651020"	"132749"	""	""	"CHEMBL155358"	""	""	""	""	"3-chloro-N'-(3-pyridin-4-ylpropanoyl)-6H-benzo[b][1,5]benzoxazepine-5-carbohydrazide"	""	"SC 51089"	"O=C(NNC(=O)N1Cc2ccccc2Oc2c1cc(Cl)cc2)CCc1ccncc1"	"XDJPQOUDGROSEU-UHFFFAOYSA-N"	"InChI=1S/C22H19ClN4O3/c23-17-6-7-20-18(13-17)27(14-16-3-1-2-4-19(16)30-20)22(29)26-25-21(28)8-5-15-9-11-24-12-10-15/h1-4,6-7,9-13H,5,8,14H2,(H,25,28)(H,26,29)"	"yes"	""	""
"8889"	"SC-67655"	""	"Peptide"	""	""	""	""	"310264670"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9799"	"Sch.336"	""	"Synthetic organic"	""	""	""	""	"354702271"	"10324989"	""	""	"CHEMBL180465"	""	""	""	""	"N-[(1S)-1-{4-[4-methoxy-2-(4-methoxybenzenesulfonyl)benzenesulfonyl]phenyl}ethyl]methanesulfonamide"	""	"analog 4j [PMID: 15664857]|SCH-336|SCH336"	"COc1ccc(c(c1)S(=O)(=O)c1ccc(cc1)OC)S(=O)(=O)c1ccc(cc1)[C@@H](NS(=O)(=O)C)C"	"NXODIUKWAVUFGF-INIZCTEOSA-N"	"InChI=1S/C23H25NO8S3/c1-16(24-33(4,25)26)17-5-10-20(11-6-17)34(27,28)22-14-9-19(32-3)15-23(22)35(29,30)21-12-7-18(31-2)8-13-21/h5-16,24H,1-4H3/t16-/m0/s1"	"yes"	""	""
"8246"	"SD-208"	""	"Synthetic organic"	""	""	""	""	"249565926"	"10316032"	""	""	"CHEMBL238125"	""	""	""	""	"2-(5-chloro-2-fluorophenyl)-N-pyridin-4-ylpteridin-4-amine"	""	"SCI-208|SD 208"	"Clc1ccc(c(c1)c1nc(Nc2ccncc2)c2c(n1)nccn2)F"	"BERLXWPRSBJFHO-UHFFFAOYSA-N"	"InChI=1S/C17H10ClFN6/c18-10-1-2-13(19)12(9-10)15-24-16-14(21-7-8-22-16)17(25-15)23-11-3-5-20-6-4-11/h1-9H,(H,20,22,23,24,25)"	"yes"	""	""
"14419"	"SDC-1801"	""	"Synthetic organic"	""	""	""	""	"523352211"	"150100552"	""	""	""	""	""	""	""	"2-(2,6-dichlorophenyl)-5-[4-(1,1-dioxo-1,4-thiazinane-4-carbonyl)anilino]oxazole-4-carboxamide"	""	"compound (2) [WO2020074461]|example 1 [WO2020074461]|SDC1801"	"ClC1=C(C(=CC=C1)Cl)C=2OC(=C(N2)C(=O)N)NC3=CC=C(C=C3)C(=O)N4CCS(CC4)(=O)=O"	"DVDLLEFLTHKNDQ-UHFFFAOYSA-N"	"InChI=1S/C21H18Cl2N4O5S/c22-14-2-1-3-15(23)16(14)19-26-17(18(24)28)20(32-19)25-13-6-4-12(5-7-13)21(29)27-8-10-33(30,31)11-9-27/h1-7,25H,8-11H2,(H2,24,28)"	"yes"	""	""
"10104"	"(S)-dimetindene"	""	"Synthetic organic"	""	""	""	""	"381118814"	"6604866"	""	""	"CHEMBL1493369"	""	""	""	""	"N,N-dimethyl-2-[3-[(1S)-1-pyridin-2-ylethyl]-1H-inden-2-yl]ethanamine"	""	"(+)-dimethindene|(+)-dimetindene|(S)-dimethindene"	"CN(CCC1=C([C@@H](c2ccccn2)C)c2c(C1)cccc2)C"	"MVMQESMQSYOVGV-OAHLLOKOSA-N"	"InChI=1S/C20H24N2/c1-15(19-10-6-7-12-21-19)20-17(11-13-22(2)3)14-16-8-4-5-9-18(16)20/h4-10,12,15H,11,13-14H2,1-3H3/t15-/m1/s1"	"yes"	""	""
"8078"	"secukinumab"	""	"Antibody"	"yes"	""	""	""	"249565758"	""	""	""	""	""	""	""	""	""	"secukinumab"	"AIN 457|AIN457|Cosentyx&reg;|NVP-AIN457"	""	""	""	"yes"	""	""
"10014"	"selectin P ligand"	"Human"	"Peptide"	""	""	""	""	"375973204"	""	"Q14242"	"ENSG00000110876"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9800"	"seletalisib"	""	"Synthetic organic"	""	""	""	""	"354702272"	"56928390"	""	""	""	""	""	""	""	"3-{8-chloro-3-[(1R)-2,2,2-trifluoro-1-({pyrido[3,2-d]pyrimidin-4-yl}amino)ethyl]quinolin-2-yl}pyridin-1-ium-1-olate"	""	"UCB 5857|UCB-5857|UCB5857"	"[O-][n+]1cccc(c1)c1nc2c(cc1[C@H](C(F)(F)F)Nc1ncnc3c1nccc3)cccc2Cl"	"LNLJHGXOFYUARS-OAQYLSRUSA-N"	"InChI=1S/C23H14ClF3N6O/c24-16-6-1-4-13-10-15(18(31-19(13)16)14-5-3-9-33(34)11-14)21(23(25,26)27)32-22-20-17(29-12-30-22)7-2-8-28-20/h1-12,21H,(H,29,30,32)/t21-/m1/s1"	"yes"	""	""
"10036"	"selinexor"	""	"Synthetic organic"	"yes"	""	""	""	"375973224"	"71481097"	""	""	"CHEMBL3545185"	""	""	""	""	"(Z)-3-[3-[3,5-bis(trifluoromethyl)phenyl]-1,2,4-triazol-1-yl]-N'-pyrazin-2-ylprop-2-enehydrazide"	"selinexor"	"compound 70 [WO2013019561A1]|KPT-330|KPT330|Nexpovio&reg;|Xpovio&reg;"	"O=C(/C=C\n1cnc(n1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)NNc1cnccn1"	"DEVSOMFAQLZNKR-RJRFIUFISA-N"	"InChI=1S/C17H11F6N7O/c18-16(19,20)11-5-10(6-12(7-11)17(21,22)23)15-26-9-30(29-15)4-1-14(31)28-27-13-8-24-2-3-25-13/h1-9H,(H,25,27)(H,28,31)/b4-1-"	"yes"	""	""
"12173"	"selnoflast"	""	"Synthetic organic"	""	""	""	""	"472319295"	"137402358"	""	""	""	""	""	""	""	"1-(1-ethylpiperidin-4-yl)sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea"	"selnoflast"	"Example 6 [WO2019008025A1]|IZD334|RG-6418|RG6418|RO7486967|somalix"	"CCN1CCC(CC1)S(=O)(=O)NC(=O)Nc1c2CCCc2cc2c1CCC2"	"OHIFQOUPTWBQLE-UHFFFAOYSA-N"	"InChI=1S/C20H29N3O3S/c1-2-23-11-9-16(10-12-23)27(25,26)22-20(24)21-19-17-7-3-5-14(17)13-15-6-4-8-18(15)19/h13,16H,2-12H2,1H3,(H2,21,22,24)"	"yes"	""	""
"9040"	"selonsertib"	""	"Synthetic organic"	""	""	""	""	"315661125"	"71245288"	""	""	""	""	""	""	""	"5-(4-cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]benzamide"	"selonsertib"	"GS-4997"	"O=C(c1cc(c(cc1F)C)n1cnc(c1)C1CC1)Nc1cccc(n1)c1nncn1C(C)C"	"YIDDLAAKOYYGJG-UHFFFAOYSA-N"	"InChI=1S/C24H24FN7O/c1-14(2)32-13-27-30-23(32)19-5-4-6-22(28-19)29-24(33)17-10-21(15(3)9-18(17)25)31-11-20(26-12-31)16-7-8-16/h4-6,9-14,16H,7-8H2,1-3H3,(H,28,29,33)"	"yes"	""	""
"9902"	"semaphorin 3A"	"Human"	"Peptide"	""	""	""	""	"363894196"	""	"Q14563"	"ENSG00000075213"	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"7048"	"S-EMCA"	""	"Synthetic organic"	""	""	""	""	"178103627"	"45483949"	""	""	"CHEMBL567640"	""	""	""	""	"(2S,4R)-4-[(3R,5S,6R,7R,8R,9S,10S,12S,13R,14S,17R)-6-ethyl-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid"	""	"6&alpha;-ethyl-23(<i>S</i>)-methyl-cholic acid|INT-777|INT777"	"CC[C@H]1[C@@H](O)[C@H]2[C@@H]3CC[C@@H]([C@@]3(C)[C@H](C[C@@H]2[C@@]2([C@H]1C[C@H](O)CC2)C)O)[C@@H](C[C@@H](C(=O)O)C)C"	"NPBCMXATLRCCLF-IRRLEISYSA-N"	"InChI=1S/C27H46O5/c1-6-17-20-12-16(28)9-10-26(20,4)21-13-22(29)27(5)18(14(2)11-15(3)25(31)32)7-8-19(27)23(21)24(17)30/h14-24,28-30H,6-13H2,1-5H3,(H,31,32)/t14-,15+,16-,17-,18-,19+,20+,21+,22+,23+,24-,26+,27-/m1/s1"	"yes"	""	""
"13939"	"seniprutug"	""	"Antibody"	"yes"	""	""	""	"513757624"	""	""	""	""	""	""	""	""	""	""	"BCD-180|BCD180"	""	""	""	"yes"	""	""
"9280"	"serlopitant"	""	"Synthetic organic"	""	""	""	""	"318164799"	"23653789"	""	""	"CHEMBL447955"	""	""	""	""	"3-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]cyclopent-2-en-1-one"	"serlopitant"	"compound 17 (Jiang <i>et al.</i> 2009)|VPD-737"	"O=C1CCC(=C1)N1C[C@@H]2[C@@H](C1)[C@@H]([C@H](CC2)O[C@@H](c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C)c1ccc(cc1)F"	"FLNYCRJBCNNHRH-OIYLJQICSA-N"	"InChI=1S/C29H28F7NO2/c1-16(19-10-20(28(31,32)33)12-21(11-19)29(34,35)36)39-26-9-4-18-14-37(23-7-8-24(38)13-23)15-25(18)27(26)17-2-5-22(30)6-3-17/h2-3,5-6,10-13,16,18,25-27H,4,7-9,14-15H2,1H3/t16-,18-,25-,26+,27+/m1/s1"	"yes"	""	""
"13796"	"serplulimab"	""	"Antibody"	"yes"	""	""	""	"507750429"	""	""	""	""	""	""	""	""	""	"serplulimab"	"HANSIZHUANG&reg; (China)|Hetronifly&reg;|HLX-10|HLX10"	""	""	""	"yes"	""	""
"9932"	"setanaxib"	""	"Synthetic organic"	""	""	""	""	"363894226"	"58496428"	""	""	""	""	""	""	""	"2-(2-chlorophenyl)-4-[3-(dimethylamino)phenyl]-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6-dione"	"setanaxib"	"GKT-137831|GKT-831|GKT137831|GKT831"	"Clc1ccccc1n1[nH]c2c(c1=O)c(c1cccc(c1)N(C)C)n(c(=O)c2)C"	"RGYQPQARIQKJKH-UHFFFAOYSA-N"	"InChI=1S/C21H19ClN4O2/c1-24(2)14-8-6-7-13(11-14)20-19-16(12-18(27)25(20)3)23-26(21(19)28)17-10-5-4-9-15(17)22/h4-12,23H,1-3H3"	"yes"	""	""
"10180"	"setipiprant"	""	"Synthetic organic"	""	""	""	""	"381118890"	"49843471"	""	""	"CHEMBL2386081"	""	""	""	""	"2-[8-fluoro-2-(naphthalene-1-carbonyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]acetic acid"	"setipiprant"	"ACT-129968|ACT129968|compound 28 [PMID: 23721423]"	"Fc1ccc2c(c1)c1CN(CCc1n2CC(=O)O)C(=O)c1cccc2c1cccc2"	"IHAXLPDVOWLUOS-UHFFFAOYSA-N"	"InChI=1S/C24H19FN2O3/c25-16-8-9-21-19(12-16)20-13-26(11-10-22(20)27(21)14-23(28)29)24(30)18-7-3-5-15-4-1-2-6-17(15)18/h1-9,12H,10-11,13-14H2,(H,28,29)"	"yes"	""	""
"10043"	"setogepram"	""	"Synthetic organic"	""	""	""	""	"375973231"	"24749700"	""	""	""	""	""	""	""	"2-(3-pentylphenyl)acetic acid"	"setogepram"	"3-pentylbenzeneacetic acid|fezagepras|PBI-4050|PBI4050"	"CCCCCc1cccc(c1)CC(=O)O"	"PEGQOIGYZLJMIB-UHFFFAOYSA-N"	"InChI=1S/C13H18O2/c1-2-3-4-6-11-7-5-8-12(9-11)10-13(14)15/h5,7-9H,2-4,6,10H2,1H3,(H,14,15)"	"yes"	""	""
"7529"	"SGC-CBP30"	""	"Synthetic organic"	""	""	""	""	"187051830"	"72201027"	""	""	""	""	""	""	""	"2-[2-(3-chloro-4-methoxyphenyl)ethyl]-5-(dimethyl-1,2-oxazol-4-yl)-1-[(2S)-2-(morpholin-4-yl)propyl]-1H-1,3-benzodiazole"	""	""	"COc1ccc(cc1Cl)CCc1nc2c(n1C[C@@H](N1CCOCC1)C)ccc(c2)c1c(C)noc1C"	"GEPYBHCJBORHCE-SFHVURJKSA-N"	"InChI=1S/C28H33ClN4O3/c1-18(32-11-13-35-14-12-32)17-33-25-8-7-22(28-19(2)31-36-20(28)3)16-24(25)30-27(33)10-6-21-5-9-26(34-4)23(29)15-21/h5,7-9,15-16,18H,6,10-14,17H2,1-4H3/t18-/m0/s1"	"yes"	"yes"	""
"10526"	"SIAIS178"	""	"Synthetic organic"	""	""	""	""	"387065608"	"139474625"	""	""	""	""	""	""	""	"N-(2-Chloro-6-methylphenyl)-2-((6-(4-(8-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methyl-thiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-8-oxooctanoyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carboxamide"	""	"compound 19 [PMID: 31539241]|SIAIS-178"	"O[C@@H]1C[C@H](N(C1)C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCC(=O)N1CCN(CC1)c1nc(C)nc(c1)Nc1ncc(s1)C(=O)Nc1c(C)cccc1Cl)C(=O)NCc1ccc(cc1)c1scnc1C"	"YGQREOJIRFCRKQ-ZIBKGDFVSA-N"	"InChI=1S/C50H62ClN11O6S2/c1-30-12-11-13-36(51)43(30)59-47(67)38-27-53-49(70-38)57-39-25-40(56-32(3)55-39)60-20-22-61(23-21-60)42(65)15-10-8-7-9-14-41(64)58-45(50(4,5)6)48(68)62-28-35(63)24-37(62)46(66)52-26-33-16-18-34(19-17-33)44-31(2)54-29-69-44/h11-13,16-19,25,27,29,35,37,45,63H,7-10,14-15,20-24,26,28H2,1-6H3,(H,52,66)(H,58,64)(H,59,67)(H,53,55,56,57)/t35-,37+,45-/m1/s1"	"yes"	""	""
"12102"	"sibeprenlimab"	""	"Antibody"	"yes"	""	""	""	"472319224"	""	""	""	""	""	""	""	""	""	"sibeprenlimab"	"sibeprenlimab-szsi|VIS-649|VIS649|Voyxact&reg;"	""	""	""	"yes"	""	""
"8257"	"sifalimumab"	""	"Antibody"	""	""	""	""	"249565937"	""	""	""	""	""	""	""	""	""	"sifalimumab"	"MDX-1103|MEDI-545|MEDI545"	""	""	""	"yes"	""	""
"7396"	"siltuximab"	""	"Antibody"	"yes"	""	""	""	"178103968"	""	""	""	""	""	""	""	""	""	"siltuximab"	"cLLB8|CNTO 328|Sylvant&reg;"	""	""	""	"yes"	""	""
"12990"	"sintilimab"	""	"Antibody"	"yes"	""	""	""	"485206111"	""	""	""	""	""	""	""	""	""	"sintilimab"	"IBI 308|IBI-308|IBI308|Tyvyt&reg;"	""	""	""	"yes"	""	""
"9289"	"siponimod"	""	"Synthetic organic"	"yes"	""	""	""	"318164808"	"44599207"	""	""	"CHEMBL2336071"	""	""	""	""	"1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid"	"siponimod"	"BAF-312|BAF312|compound 32 [PMID: 24900670]|Mayzent&reg;"	"CCc1cc(ccc1CN1CC(C1)C(=O)O)/C(=N/OCc1ccc(c(c1)C(F)(F)F)C1CCCCC1)/C"	"KIHYPELVXPAIDH-HNSNBQBZSA-N"	"InChI=1S/C29H35F3N2O3/c1-3-21-14-23(10-11-24(21)15-34-16-25(17-34)28(35)36)19(2)33-37-18-20-9-12-26(22-7-5-4-6-8-22)27(13-20)29(30,31)32/h9-14,22,25H,3-8,15-18H2,1-2H3,(H,35,36)/b33-19+"	"yes"	""	""
"6031"	"sirolimus"	""	"Synthetic organic"	"yes"	""	""	""	"178102653"	"5284616"	""	""	"CHEMBL413"	""	""	""	""	""	"sirolimus"	"AY-22989|Fyarro&reg; (sirolimus albumin-bound particles)|Rapamune&reg;|rapamycin|WY-090217"	"CO[C@@H]1C[C@@H](CC[C@H]1O)C[C@H]([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H](CC[C@H]2C)C[C@H](OC)/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C1)C)/C)O)OC)C)C)/C)C"	"QFJCIRLUMZQUOT-HPLJOQBZSA-N"	"InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1"	"yes"	""	""
"9514"	"SIRT1 activator 3"	""	"Synthetic organic"	""	""	""	""	"336446901"	"1882365"	""	""	""	""	""	""	""	"2-amino-N-cyclopentyl-1-(3-methoxypropyl)pyrrolo[3,2-b]quinoxaline-3-carboxamide"	""	"SA-3|SA3"	"COCCCn1c2nc3ccccc3nc2c(c1N)C(=O)NC1CCCC1"	"VNOFYGGJZCEPAH-UHFFFAOYSA-N"	"InChI=1S/C20H25N5O2/c1-27-12-6-11-25-18(21)16(20(26)22-13-7-2-3-8-13)17-19(25)24-15-10-5-4-9-14(15)23-17/h4-5,9-10,13H,2-3,6-8,11-12,21H2,1H3,(H,22,26)"	"yes"	""	""
"7989"	"sirukumab"	""	"Antibody"	""	""	""	""	"249565670"	""	""	""	""	""	""	""	""	""	"sirukumab"	"CNTO 136|CNTO-136|Plivensia (proposed trade name)"	""	""	""	"yes"	""	""
"10641"	"SLM6071469"	""	"Synthetic organic"	""	""	""	""	"404859088"	"131981409"	""	""	""	""	""	""	""	"(2S)-2-[3-[3-(trifluoromethyl)-4-[[4-(trifluoromethyl)phenyl]methoxy]phenyl]-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboximidamide"	""	"compound 10 [PMID: 31895563]"	"NC(=N)N1CCC[C@H]1c1onc(n1)c1ccc(c(c1)C(F)(F)F)OCc1ccc(cc1)C(F)(F)F"	"QOYVZPSXPWIXAV-INIZCTEOSA-N"	"InChI=1S/C22H19F6N5O2/c23-21(24,25)14-6-3-12(4-7-14)11-34-17-8-5-13(10-15(17)22(26,27)28)18-31-19(35-32-18)16-2-1-9-33(16)20(29)30/h3-8,10,16H,1-2,9,11H2,(H3,29,30)/t16-/m0/s1"	"yes"	""	""
"11129"	"SNG001"	""	"Peptide"	""	""	""	""	"434122189"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9260"	"SNX0723"	""	"Synthetic organic"	""	""	""	""	"315661335"	"67495834"	""	""	"CHEMBL3104858"	""	""	""	""	"2-fluoro-6-[[(3S)-oxolan-3-yl]amino]-4-(3,6,6-trimethyl-4-oxo-5,7-dihydroindol-1-yl)benzamide"	""	""	"NC(=O)c1c(N[C@@H]2COCC2)cc(cc1F)n1cc(c2c1CC(C)(C)CC2=O)C"	"GAGDTKJJVCLACJ-ZDUSSCGKSA-N"	"InChI=1S/C22H26FN3O3/c1-12-10-26(17-8-22(2,3)9-18(27)19(12)17)14-6-15(23)20(21(24)28)16(7-14)25-13-4-5-29-11-13/h6-7,10,13,25H,4-5,8-9,11H2,1-3H3,(H2,24,28)/t13-/m0/s1"	"yes"	""	""
"10094"	"sofnobrutinib"	""	"Synthetic organic"	""	""	""	""	"381118804"	"87056204"	""	""	""	""	""	""	""	"2-(3-{4-Amino-6-[(1-methyl-1H-pyrazol-4-yl)amino]-1,3,5-triazin-2-yl}-2-(hydroxymethyl)phenyl)-6-cyclopropyl-8-fluoroisoquinolin-1(2H)-one"	"sofnobrutinib"	"compound 4b [PMID: 30216722]"	"OCc1c(cccc1n1ccc2c(c1=O)c(F)cc(c2)C1CC1)c1nc(N)nc(n1)Nc1cnn(c1)C"	"RQYDQAPLARKISN-UHFFFAOYSA-N"	"InChI=1S/C26H23FN8O2/c1-34-12-17(11-29-34)30-26-32-23(31-25(28)33-26)18-3-2-4-21(19(18)13-36)35-8-7-15-9-16(14-5-6-14)10-20(27)22(15)24(35)37/h2-4,7-12,14,36H,5-6,13H2,1H3,(H3,28,30,31,32,33)"	"yes"	""	""
"9697"	"solcitinib"	""	"Synthetic organic"	""	""	""	""	"348353656"	"44603362"	""	""	"CHEMBL3301606"	""	""	""	""	"N-[5-[4-(3,3-dimethylazetidine-1-carbonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide"	"solcitinib"	"compound 1 [WO2010149771]|GLPG-0778|GLPG0778|GSK2586184"	"O=C(C1CC1)Nc1nn2c(n1)cccc2c1ccc(cc1)C(=O)N1CC(C1)(C)C"	"MPYACSQFXVMWNO-UHFFFAOYSA-N"	"InChI=1S/C22H23N5O2/c1-22(2)12-26(13-22)20(29)16-10-6-14(7-11-16)17-4-3-5-18-23-21(25-27(17)18)24-19(28)15-8-9-15/h3-7,10-11,15H,8-9,12-13H2,1-2H3,(H,24,25,28)"	"yes"	""	""
"10491"	"sonelokimab"	""	"Antibody"	""	""	""	""	"385612250"	""	""	""	""	""	""	""	""	""	"sonelokimab"	"IL17-MS3086|IL17MS3086|M-1095|M1095|MSB-0010841|MSB0010841|SEQ ID 836 [WO2012156219A1]"	""	""	""	"yes"	""	""
"7946"	"sotrastaurin"	""	"Synthetic organic"	""	""	""	""	"249565629"	"10296883"	""	""	"CHEMBL565612"	""	""	""	""	"3-(1H-indol-3-yl)-4-[2-(4-methylpiperazin-1-yl)quinazolin-4-yl]pyrrole-2,5-dione"	"sotrastaurin"	"AEB-071|AEB071"	"CN1CCN(CC1)c1nc2ccccc2c(n1)C1=C(C(=O)NC1=O)c1c[nH]c2c1cccc2"	"OAVGBZOFDPFGPJ-UHFFFAOYSA-N"	"InChI=1S/C25H22N6O2/c1-30-10-12-31(13-11-30)25-27-19-9-5-3-7-16(19)22(28-25)21-20(23(32)29-24(21)33)17-14-26-18-8-4-2-6-15(17)18/h2-9,14,26H,10-13H2,1H3,(H,29,32,33)"	"yes"	""	""
"8250"	"sotuletinib"	""	"Synthetic organic"	""	""	""	""	"249565930"	"46184986"	""	""	""	""	""	""	""	"4-[[2-[[(1R,2R)-2-hydroxycyclohexyl]amino]-1,3-benzothiazol-6-yl]oxy]-N-methylpyridine-2-carboxamide"	"sotuletinib"	"BLZ 945|BLZ-945|BLZ945"	"CNC(=O)c1nccc(c1)Oc1ccc2c(c1)sc(n2)N[C@@H]1CCCC[C@H]1O"	"ADZBMFGQQWPHMJ-RHSMWYFYSA-N"	"InChI=1S/C20H22N4O3S/c1-21-19(26)16-10-13(8-9-22-16)27-12-6-7-15-18(11-12)28-20(24-15)23-14-4-2-3-5-17(14)25/h6-11,14,17,25H,2-5H2,1H3,(H,21,26)(H,23,24)/t14-,17-/m1/s1"	"yes"	""	""
"9037"	"SP-4206"	""	"Synthetic organic"	""	""	""	""	"315661122"	"5288251"	""	""	"CHEMBL429852"	""	""	""	""	"5-[[2,3-dichloro-4-[5-[1-[2-[[(2R)-2-(diaminomethylideneamino)-4-methylpentanoyl]amino]acetyl]piperidin-4-yl]-1-methylpyrazol-3-yl]phenoxy]methyl]furan-2-carboxylic acid"	""	"compound 13 [PMID:12656598]|SP4206"	"CC(C[C@H](C(=O)NCC(=O)N1CCC(CC1)c1cc(nn1C)c1ccc(c(c1Cl)Cl)OCc1ccc(o1)C(=O)O)N=C(N)N)C"	"VNZHOIDQBPFEJU-OAQYLSRUSA-N"	"InChI=1S/C30H37Cl2N7O6/c1-16(2)12-21(36-30(33)34)28(41)35-14-25(40)39-10-8-17(9-11-39)22-13-20(37-38(22)3)19-5-7-23(27(32)26(19)31)44-15-18-4-6-24(45-18)29(42)43/h4-7,13,16-17,21H,8-12,14-15H2,1-3H3,(H,35,41)(H,42,43)(H4,33,34,36)/t21-/m1/s1"	"yes"	""	""
"5273"	"SP600125"	""	"Synthetic organic"	""	""	""	""	"178101956"	"8515"	""	""	""	""	""	""	""	""	""	"1,9-pyrazoloanthrone|JNK Inhibitor II|SP-600125"	"O=c1c2ccccc2c2c3c1cccc3[nH]n2"	"ACPOUJIDANTYHO-UHFFFAOYSA-N"	"InChI=1S/C14H8N2O/c17-14-9-5-2-1-4-8(9)13-12-10(14)6-3-7-11(12)15-16-13/h1-7H,(H,15,16)"	"yes"	""	""
"8448"	"sparsentan"	""	"Synthetic organic"	"yes"	""	""	""	"252166658"	"10257882"	""	""	"CHEMBL539423"	""	""	""	""	"2-[4-[(2-butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide"	"sparsentan"	"<b>DARA</b>-a (<b>D</b>ual <b>A</b>cting <b>R</b>eceptor <b>A</b>ntagonist of angiotension and endothelin receptors)|BMS-346567|compound 7 [PMID 15634011]|Filspari&reg;|RE-021|retrophin"	"CCCCC1=NC2(C(=O)N1Cc1ccc(c(c1)COCC)c1ccccc1S(=O)(=O)Nc1noc(c1C)C)CCCC2"	"WRFHGDPIDHPWIQ-UHFFFAOYSA-N"	"InChI=1S/C32H40N4O5S/c1-5-7-14-29-33-32(17-10-11-18-32)31(37)36(29)20-24-15-16-26(25(19-24)21-40-6-2)27-12-8-9-13-28(27)42(38,39)35-30-22(3)23(4)41-34-30/h8-9,12-13,15-16,19H,5-7,10-11,14,17-18,20-21H2,1-4H3,(H,34,35)"	"yes"	""	""
"10140"	"spartalizumab"	""	"Antibody"	""	""	""	""	"381118850"	""	""	""	""	""	""	""	""	""	"spartalizumab"	"NPV-PDR001|NPVPDR001|PDR-001|PDR001"	""	""	""	"yes"	""	""
"7837"	"spebrutinib"	""	"Synthetic organic"	""	""	""	""	"223366168"	"59174488"	""	""	"CHEMBL3301625"	""	""	""	""	"N-[3-[[5-fluoro-2-[4-(2-methoxyethoxy)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide"	"spebrutinib"	"AVL 292|AVL-292|cc-292"	"COCCOc1ccc(cc1)Nc1ncc(c(n1)Nc1cccc(c1)NC(=O)C=C)F"	"KXBDTLQSDKGAEB-UHFFFAOYSA-N"	"InChI=1S/C22H22FN5O3/c1-3-20(29)25-16-5-4-6-17(13-16)26-21-19(23)14-24-22(28-21)27-15-7-9-18(10-8-15)31-12-11-30-2/h3-10,13-14H,1,11-12H2,2H3,(H,25,29)(H2,24,26,27,28)"	"yes"	""	""
"12169"	"spesolimab"	""	"Antibody"	"yes"	""	""	""	"472319291"	""	""	""	""	""	""	""	""	""	"spesolimab"	"BI-655130|BI655130|spesolimab-sbzo|Spevigo&reg;"	""	""	""	"yes"	""	""
"10054"	"sphingomyelin synthase 2 inhibitor 15w"	""	"Synthetic organic"	""	""	""	""	"375973242"	"134813905"	""	""	""	""	""	""	""	"4-[(2-chloro-5-fluorophenyl)methoxy]-N-(pyridin-3-yl)-1,2-benzoxazol-3-amine"	""	"compound 15w [PMID: 30074791]"	"Fc1ccc(c(c1)COc1cccc2c1c(no2)Nc1cccnc1)Cl"	"VZWFUUUUCXTDJT-UHFFFAOYSA-N"	"InChI=1S/C19H13ClFN3O2/c20-15-7-6-13(21)9-12(15)11-25-16-4-1-5-17-18(16)19(24-26-17)23-14-3-2-8-22-10-14/h1-10H,11H2,(H,23,24)"	"yes"	""	""
"10130"	"SPRi3"	""	"Synthetic organic"	""	""	""	""	"381118840"	"52911386"	""	""	"CHEMBL3948731"	""	""	""	""	"N-[2-(5-hydroxy-2-methyl-1H-indol-3-yl)ethyl]-2-methoxyacetamide"	""	"example 23 [WO2011047156]|SPR inhibitor 3"	"COCC(=O)NCCc1c(C)[nH]c2c1cc(O)cc2"	"YBXBWBBVLXZQBJ-UHFFFAOYSA-N"	"InChI=1S/C14H18N2O3/c1-9-11(5-6-15-14(18)8-19-2)12-7-10(17)3-4-13(12)16-9/h3-4,7,16-17H,5-6,8H2,1-2H3,(H,15,18)"	"yes"	""	""
"10143"	"SR1001"	""	"Synthetic organic"	""	""	""	""	"381118853"	"44241473"	""	""	"CHEMBL3094388"	""	""	""	""	"N-[5-[[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide"	""	"SR-1001"	"CC(=O)Nc1nc(c(s1)S(=O)(=O)Nc1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O)C"	"OZBSSKGBKHOLGA-UHFFFAOYSA-N"	"InChI=1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)"	"yes"	""	""
"751"	"SR144528"	""	"Synthetic organic"	""	""	""	""	"135651075"	"3081355"	""	""	"CHEMBL381791"	""	""	""	""	"5-(4-chloro-3-methylphenyl)-1-[(4-methylphenyl)methyl]-N-[(1S,4R,6S)-1,5,5-trimethyl-6-bicyclo[2.2.1]heptanyl]pyrazole-3-carboxamide"	""	"SR 144528|SR-144528"	"Cc1ccc(cc1)Cn1nc(cc1c1ccc(c(c1)C)Cl)C(=O)N[C@H]1[C@@]2(C)CC[C@@H](C1(C)C)C2"	"SUGVYNSRNKFXQM-XRHWURSXSA-N"	"InChI=1S/C29H34ClN3O/c1-18-6-8-20(9-7-18)17-33-25(21-10-11-23(30)19(2)14-21)15-24(32-33)26(34)31-27-28(3,4)22-12-13-29(27,5)16-22/h6-11,14-15,22,27H,12-13,16-17H2,1-5H3,(H,31,34)/t22-,27-,29+/m1/s1"	"yes"	""	""
"10145"	"SR1555"	""	"Synthetic organic"	""	""	""	""	"381118855"	"71470549"	""	""	"CHEMBL3218917"	""	""	""	""	"1-[4-[[4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]methyl]piperazin-1-yl]ethanone"	""	"SR-1555"	"CC(=O)N1CCN(CC1)Cc1ccc(cc1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O"	"LTFVNEZXOPUABB-UHFFFAOYSA-N"	"InChI=1S/C22H22F6N2O2/c1-15(31)30-12-10-29(11-13-30)14-16-2-4-17(5-3-16)18-6-8-19(9-7-18)20(32,21(23,24)25)22(26,27)28/h2-9,32H,10-14H2,1H3"	"yes"	""	""
"10144"	"SR2211"	""	"Synthetic organic"	""	""	""	""	"381118854"	"51035449"	""	""	"CHEMBL2137199"	""	""	""	""	"1,1,1,3,3,3-hexafluoro-2-[3-fluoro-4-[4-[[4-(pyridin-4-ylmethyl)piperazin-1-yl]methyl]phenyl]phenyl]propan-2-ol"	""	"SR-2211"	"Fc1cc(ccc1c1ccc(cc1)CN1CCN(CC1)Cc1ccncc1)C(C(F)(F)F)(C(F)(F)F)O"	"KVHKWAZUPPBMLL-UHFFFAOYSA-N"	"InChI=1S/C26H24F7N3O/c27-23-15-21(24(37,25(28,29)30)26(31,32)33)5-6-22(23)20-3-1-18(2-4-20)16-35-11-13-36(14-12-35)17-19-7-9-34-10-8-19/h1-10,15,37H,11-14,16-17H2"	"yes"	""	""
"3329"	"SR2640"	""	"Synthetic organic"	""	""	""	""	"178100361"	"128355"	""	""	"CHEMBL18132"	""	""	""	""	"2-{[3-(quinolin-2-ylmethoxy)phenyl]amino}benzoic acid"	""	"SR 2640|SR-2640"	"OC(=O)c1ccccc1Nc1cccc(c1)OCc1ccc2c(n1)cccc2"	"LMPZHLXYBWGGNT-UHFFFAOYSA-N"	"InChI=1S/C23H18N2O3/c26-23(27)20-9-2-4-11-22(20)24-17-7-5-8-19(14-17)28-15-18-13-12-16-6-1-3-10-21(16)25-18/h1-14,24H,15H2,(H,26,27)"	"yes"	""	""
"9578"	"SR8185"	""	"Synthetic organic"	""	""	""	""	"336446964"	"56646418"	""	""	""	""	""	""	""	"N-[3-[[4-(3-cyano-4-pyrrolidin-1-ylphenyl)pyrimidin-2-yl]amino]phenyl]pyrrolidine-1-carboxamide"	""	"SR-8185"	"N#Cc1cc(ccc1N1CCCC1)c1ccnc(n1)Nc1cccc(c1)NC(=O)N1CCCC1"	"MQAQKNLCUSPSAF-UHFFFAOYSA-N"	"InChI=1S/C26H27N7O/c27-18-20-16-19(8-9-24(20)32-12-1-2-13-32)23-10-11-28-25(31-23)29-21-6-5-7-22(17-21)30-26(34)33-14-3-4-15-33/h5-11,16-17H,1-4,12-15H2,(H,30,34)(H,28,29,31)"	"yes"	""	""
"7703"	"SRT1720"	""	"Synthetic organic"	""	""	""	""	"223366036"	"24180125"	""	""	"CHEMBL257991"	""	""	""	""	"N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide"	""	""	"O=C(c1cnc2c(n1)cccc2)Nc1ccccc1c1cn2c(n1)scc2CN1CCNCC1"	"IASPBORHOMBZMY-UHFFFAOYSA-N"	"InChI=1S/C25H23N7OS/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31/h1-8,13,15-16,26H,9-12,14H2,(H,29,33)"	"yes"	""	""
"9515"	"SRT2104"	""	"Synthetic organic"	""	""	""	""	"336446902"	"25108829"	""	""	""	""	""	""	""	"4-methyl-N-[2-[3-(morpholin-4-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]-2-pyridin-3-yl-1,3-thiazole-5-carboxamide"	""	"compound 4 [Ng <i>et al.</i>, 2013]|GSK2245840|SRT-2104"	"O=C(c1sc(nc1C)c1cccnc1)Nc1ccccc1c1cn2c(n1)scc2CN1CCOCC1"	"LAMQVIQMVKWXOC-UHFFFAOYSA-N"	"InChI=1S/C26H24N6O2S2/c1-17-23(36-25(28-17)18-5-4-8-27-13-18)24(33)29-21-7-3-2-6-20(21)22-15-32-19(16-35-26(32)30-22)14-31-9-11-34-12-10-31/h2-8,13,15-16H,9-12,14H2,1H3,(H,29,33)"	"yes"	""	""
"10490"	"SS-208"	""	"Synthetic organic"	""	""	""	""	"385612249"	"135348858"	""	""	""	""	""	""	""	""	""	"compound 7b [PMID: 31414801]|SS208"	"ONC(=O)c1noc(c1)CCNC(=O)c1ccc(c(c1)Cl)Cl"	"JFGOILLZIAIYGA-UHFFFAOYSA-N"	"InChI=1S/C13H11Cl2N3O4/c14-9-2-1-7(5-10(9)15)12(19)16-4-3-8-6-11(18-22-8)13(20)17-21/h1-2,5-6,21H,3-4H2,(H,16,19)(H,17,20)"	"yes"	""	""
"13785"	"stapokibart"	""	"Antibody"	"yes"	""	""	""	"507750418"	""	""	""	""	""	""	""	""	""	"stapokibart"	"CM-310|CM310"	""	""	""	"yes"	""	""
"5055"	"stem cell factor"	"Human"	"Peptide"	""	""	""	""	"178101749"	""	"P21583"	"ENSG00000049130"	""	""	""	""	""	""	""	"c-Kit ligand|SCF"	""	""	""	"yes"	""	""
"10127"	"STING agonist 2"	""	"Synthetic organic"	""	""	""	""	"381118837"	"132000066"	""	""	""	""	""	""	""	"1-{4-[5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-1H-1,3-benzodiazol-1-yl]butyl}-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-1H-1,3-benzodiazole-5-carboxamide"	""	""	"CCn1nc(cc1C(=O)Nc1nc2c(n1CCCCn1c(NC(=O)c3cc(nn3CC)C)nc3c1ccc(c3)C(=O)N)ccc(c2)C(=O)N)C"	"ICZSAXDKFXTSGL-UHFFFAOYSA-N"	"InChI=1S/C34H38N12O4/c1-5-45-27(15-19(3)41-45)31(49)39-33-37-23-17-21(29(35)47)9-11-25(23)43(33)13-7-8-14-44-26-12-10-22(30(36)48)18-24(26)38-34(44)40-32(50)28-16-20(4)42-46(28)6-2/h9-12,15-18H,5-8,13-14H2,1-4H3,(H2,35,47)(H2,36,48)(H,37,39,49)(H,38,40,50)"	"yes"	""	""
"10128"	"STING agonist 3"	""	"Synthetic organic"	""	""	""	""	"381118838"	"131986624"	""	""	""	""	""	""	""	"1-[(2E)-4-[5-carbamoyl-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-7-[3-(morpholin-4-yl)propoxy]-1H-1,3-benzodiazol-1-yl]but-2-en-1-yl]-2-(1-ethyl-3-methyl-1H-pyrazole-5-amido)-7-methoxy-1H-1,3-benzodiazole-5-carboxamide"	""	"compound 3 [PMID: 30405246]|diABZI|diABZI STING agonist-1"	"COc1cc(cc2c1n(C/C=C/Cn1c(NC(=O)c3cc(nn3CC)C)nc3c1c(OCCCN1CCOCC1)cc(c3)C(=O)N)c(n2)NC(=O)c1cc(nn1CC)C)C(=O)N"	"JGLMVXWAHNTPRF-CMDGGOBGSA-N"	"InChI=1S/C42H51N13O7/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(43)56)23-33(60-5)35(29)52(41)12-8-9-13-53-36-30(46-42(53)48-40(59)32-20-26(4)50-55(32)7-2)22-28(38(44)57)24-34(36)62-16-10-11-51-14-17-61-18-15-51/h8-9,19-24H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59)/b9-8+"	"yes"	""	""
"5425"	"sulindac"	""	"Synthetic organic"	"yes"	""	""	""	"178102078"	"1548887"	""	""	"CHEMBL15770"	""	""	""	""	"2-[(1Z)-5-fluoro-1-[(4-methanesulfinylphenyl)methylidene]-2-methyl-1H-inden-3-yl]acetic acid"	"sulindac"	"Clinoril&reg;|HLX-0201|HLX0201"	"OC(=O)CC1=C(C)/C(=C/c2ccc(cc2)S(=O)C)/c2c1cc(F)cc2"	"MLKXDPUZXIRXEP-MFOYZWKCSA-N"	"InChI=1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-"	"yes"	""	""
"4356"	"[<sup>3</sup>H]resolvin D1"	""	"Synthetic organic"	""	""	"yes"	"yes"	"178101173"	"73755062"	""	""	""	""	""	""	""	""	""	"[<sup>3</sup>H]-RvD1"	"CC/C=C\C[C@@H](/C=C/C=C\C=C\C=C\[C@@H]([C@H](C/C=C\CCC(=O)O)O)O)O"	"OIWTWACQMDFHJG-LDOXQWQISA-N"	"InChI=1S/C22H32O5/c1-2-3-9-14-19(23)15-10-6-4-5-7-11-16-20(24)21(25)17-12-8-13-18-22(26)27/h3-12,15-16,19-21,23-25H,2,13-14,17-18H2,1H3,(H,26,27)/b6-4-,7-5+,9-3-,12-8-,15-10+,16-11+/t19-,20-,21-/m0/s1"	"yes"	""	""
"2901"	"[<sup>3</sup>H]resolvin E1"	""	"Synthetic organic"	""	""	"yes"	"yes"	"135651571"	"10473088"	""	""	""	""	""	""	""	"(5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid"	""	"[(3)H]-labeled RvE1|[<sup>3</sup>H]RvE1"	"CC[C@@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O"	"AOPOCGPBAIARAV-JJVMZPRHSA-N"	"InChI=1S/C20H30O5/c1-2-17(21)11-8-5-9-14-18(22)12-6-3-4-7-13-19(23)15-10-16-20(24)25/h3-9,11-13,17-19,21-23H,2,10,14-16H2,1H3,(H,24,25)/b4-3+,9-5-,11-8+,12-6+,13-7-/t17-,18-,19+/m0/s1"	"yes"	""	""
"7298"	"suprofen"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178103871"	"5359"	""	""	"CHEMBL956"	""	""	""	""	"2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid"	"suprofen"	"Profenal&reg;|R-25061"	"OC(=O)C(c1ccc(cc1)C(=O)c1cccs1)C"	"MDKGKXOCJGEUJW-UHFFFAOYSA-N"	"InChI=1S/C14H12O3S/c1-9(14(16)17)10-4-6-11(7-5-10)13(15)12-3-2-8-18-12/h2-9H,1H3,(H,16,17)"	"yes"	""	""
"9807"	"sutimlimab"	""	"Antibody"	"yes"	""	""	""	"354702279"	""	""	""	""	""	""	""	""	""	"sutimlimab"	"BIVV009|Enjaymo&reg;|IPN-009|IPN009|sutimlimab-jome|TNT009"	""	""	""	"yes"	""	""
"10165"	"SX682"	""	"Synthetic organic"	""	""	""	""	"381118875"	"90467234"	""	""	""	""	""	""	""	"[2-[[5-[(4-fluorophenyl)carbamoyl]pyrimidin-2-yl]sulfanylmethyl]-4-(trifluoromethoxy)phenyl]boronic acid"	""	""	"Fc1ccc(cc1)NC(=O)c1cnc(nc1)SCc1cc(ccc1B(O)O)OC(F)(F)F"	"SDUDZBCEHIZMFZ-UHFFFAOYSA-N"	"InChI=1S/C19H14BF4N3O4S/c21-13-1-3-14(4-2-13)27-17(28)12-8-25-18(26-9-12)32-10-11-7-15(31-19(22,23)24)5-6-16(11)20(29)30/h1-9,29-30H,10H2,(H,27,28)"	"yes"	""	""
"6046"	"Syk inhibitor"	""	"Synthetic organic"	""	""	""	""	"178102668"	"6419747"	""	""	"CHEMBL104279"	""	""	""	""	"(3Z)-3-[(1-methyl-1H-indol-3-yl)methylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide"	""	"K00564a|spleen tyrosine kinase inhibitor"	"O=C1Nc2c(/C/1=C/c1cn(c3c1cccc3)C)cc(cc2)S(=O)(=O)N"	"MLKHXLFEYOOYEY-NVNXTCNLSA-N"	"InChI=1S/C18H15N3O3S/c1-21-10-11(13-4-2-3-5-17(13)21)8-15-14-9-12(25(19,23)24)6-7-16(14)20-18(15)22/h2-10H,1H3,(H,20,22)(H2,19,23,24)/b15-8-"	"yes"	""	""
"6047"	"Syk inhibitor II"	""	"Synthetic organic"	""	""	""	""	"178102669"	"9549296"	""	""	"CHEMBL471901"	""	""	""	""	"2-[(2-aminoethyl)amino]-4-{[3-(trifluoromethyl)phenyl]amino}pyrimidine-5-carboxamide"	""	"K00592a"	"NCCNc1ncc(c(n1)Nc1cccc(c1)C(F)(F)F)C(=O)N"	"FQNFLNSVHWCZML-UHFFFAOYSA-N"	"InChI=1S/C14H15F3N6O/c15-14(16,17)8-2-1-3-9(6-8)22-12-10(11(19)24)7-21-13(23-12)20-5-4-18/h1-3,6-7H,4-5,18H2,(H2,19,24)(H2,20,21,22,23)"	"yes"	""	""
"12311"	"SZM679"	""	"Synthetic organic"	""	""	""	""	"479821102"	"166176959"	""	""	""	""	""	""	""	"N-(5-Fluoro-6-(4-fluoro-3-(2-(3-(trifluoromethoxy)phenyl)acetamido)phenoxy)benzo[d]thiazol-2-yl)-3-oxocyclobutane-1-carboxamide"	""	"SZM-679"	"O=C(C1CC(=O)C1)Nc1nc2cc(F)c(Oc3ccc(F)c(NC(=O)Cc4cccc(OC(F)(F)F)c4)c3)cc2s1"	"OFQHMPFSITXRSS-UHFFFAOYSA-N"	"InChI=1S/C27H18F5N3O5S/c28-18-5-4-16(10-20(18)33-24(37)7-13-2-1-3-17(6-13)40-27(30,31)32)39-22-12-23-21(11-19(22)29)34-26(41-23)35-25(38)14-8-15(36)9-14/h1-6,10-12,14H,7-9H2,(H,33,37)(H,34,35,38)"	"yes"	""	""
"2755"	"T0901317"	""	"Synthetic organic"	""	""	""	""	"135651223"	"447912"	""	""	"CHEMBL62136"	""	""	""	""	"N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide"	""	"T 0901317|T-0901317"	"FC(CN(S(=O)(=O)c1ccccc1)c1ccc(cc1)C(C(F)(F)F)(C(F)(F)F)O)(F)F"	"SGIWFELWJPNFDH-UHFFFAOYSA-N"	"InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2"	"yes"	""	""
"8000"	"tabalumab"	""	"Antibody"	""	""	""	""	"249565680"	""	""	""	""	""	""	""	""	""	"tabalumab"	"LY 2127399|LY2127399"	""	""	""	"yes"	""	""
"10077"	"tadekinig alfa"	""	"Peptide"	""	""	""	""	"375973264"	""	""	""	""	""	""	""	""	""	"tadekinig alfa"	""	""	""	""	"yes"	""	""
"11131"	"tafasitamab"	""	"Antibody"	"yes"	""	""	""	"434122191"	""	""	""	""	""	""	""	""	""	"tafasitamab"	"Minjuvi&reg;|Monjuvi&reg;|MOR-208|MOR00208|MOR208|tafasitamab-cxix|Xmab5574"	""	""	""	"yes"	""	""
"13795"	"tagitanlimab"	""	"Antibody"	"yes"	""	""	""	"507750428"	""	""	""	""	""	""	""	""	""	"tagitanlimab"	"A-167|Cotelet&reg;|HBM-9167|KL-A167|KLA167"	""	""	""	"yes"	""	""
"10387"	"TAK-632"	""	"Synthetic organic"	""	""	""	""	"384403666"	"46209401"	""	""	"CHEMBL3125890"	""	""	""	""	"N-[7-cyano-6-[4-fluoro-3-[[2-[3-(trifluoromethyl)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]cyclopropanecarboxamide"	""	"compound 8B [PMID: 23906342]|TAK632"	"N#Cc1c(ccc2c1sc(n2)NC(=O)C1CC1)Oc1ccc(c(c1)NC(=O)Cc1cccc(c1)C(F)(F)F)F"	"OJFKUJDRGJSAQB-UHFFFAOYSA-N"	"InChI=1S/C27H18F4N4O3S/c28-19-7-6-17(12-21(19)33-23(36)11-14-2-1-3-16(10-14)27(29,30)31)38-22-9-8-20-24(18(22)13-32)39-26(34-20)35-25(37)15-4-5-15/h1-3,6-10,12,15H,4-5,11H2,(H,33,36)(H,34,35,37)"	"yes"	""	""
"9328"	"TAK-715"	""	"Synthetic organic"	""	""	""	""	"318164847"	"9952773"	""	""	"CHEMBL363648"	""	""	""	""	"N-[4-[2-ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl]pyridin-2-yl]benzamide"	""	"compound 8h [PMID: 16162000]|TAK 715|TAK0715"	"CCc1nc(c(s1)c1ccnc(c1)NC(=O)c1ccccc1)c1cccc(c1)C"	"HEKAIDKUDLCBRU-UHFFFAOYSA-N"	"InChI=1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)"	"yes"	""	""
"783"	"TAK-779"	""	"Synthetic organic"	""	""	""	""	"135651230"	"183790"	""	""	"CHEMBL1178786"	""	""	""	""	"dimethyl-[[4-[[3-(4-methylphenyl)8,9-dihydro-7H-benzo[7]annulene-6-carbonyl]amino]phenyl]methyl]-(oxan-4-yl)azanium"	""	"TAK779"	"Cc1ccc(cc1)c1ccc2c(c1)C=C(CCC2)C(=O)Nc1ccc(cc1)C[N+](C1CCOCC1)(C)C"	"XNHZXMPLVSJQFK-UHFFFAOYSA-O"	"InChI=1S/C33H38N2O2/c1-24-7-11-27(12-8-24)28-14-13-26-5-4-6-29(22-30(26)21-28)33(36)34-31-15-9-25(10-16-31)23-35(2,3)32-17-19-37-20-18-32/h7-16,21-22,32H,4-6,17-20,23H2,1-3H3/p+1"	"yes"	""	""
"9867"	"TAK-828F"	""	"Synthetic organic"	""	""	""	""	"363894161"	"118622692"	""	""	""	""	""	""	""	"2-[3-[(5R)-5-[(7-fluoro-1,1-dimethyl-2,3-dihydroinden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-5H-1,6-naphthyridine-6-carbonyl]cyclobutyl]acetic acid"	""	"compound 10 [PMID: 29510038]|TAK-828|TAK828F"	"COc1ccc2c(n1)CCN([C@H]2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C)C(=O)[C@@H]1C[C@@H](C1)CC(=O)O"	"ICMFYVOUDGRBLG-VFHHBZAHSA-N"	"InChI=1S/C28H32FN3O5/c1-28(2)8-6-16-13-18(14-20(29)24(16)28)30-26(35)25-19-4-5-22(37-3)31-21(19)7-9-32(25)27(36)17-10-15(11-17)12-23(33)34/h4-5,13-15,17,25H,6-12H2,1-3H3,(H,30,35)(H,33,34)/t15-,17+,25-/m1/s1"	"yes"	""	""
"11305"	"TAK-981"	""	"Synthetic organic"	""	""	""	""	"434321740"	"118628567"	""	""	""	""	""	""	""	"[(1R,2S,4R)-4-[[5-[4-[(1R)-7-chloro-1,2,3,4-tetrahydroisoquinolin-1-yl]-5-methylthiophene-2-carbonyl]pyrimidin-4-yl]amino]-2-hydroxycyclopentyl]methyl sulfamate"	""	"Example 133 [WO2016004136A1]|I-263a [WO2016004136A1]|subasumstat (proposed INN)|TAK981"	"Clc1ccc2c(c1)[C@@H](NCC2)c1cc(sc1C)C(=O)c1cncnc1N[C@@H]1C[C@@H]([C@H](C1)O)COS(=O)(=O)N"	"LXRZVMYMQHNYJB-UNXOBOICSA-N"	"InChI=1S/C25H28ClN5O5S2/c1-13-18(23-19-7-16(26)3-2-14(19)4-5-29-23)9-22(37-13)24(33)20-10-28-12-30-25(20)31-17-6-15(21(32)8-17)11-36-38(27,34)35/h2-3,7,9-10,12,15,17,21,23,29,32H,4-6,8,11H2,1H3,(H2,27,34,35)(H,28,30,31)/t15-,17-,21+,23+/m1/s1"	"yes"	""	""
"9655"	"Takinib"	""	"Synthetic organic"	""	""	""	""	"348353615"	"37750349"	""	""	""	""	""	""	""	"3-N-(1-propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide"	""	""	"CCCn1/c(=N/C(=O)c2cccc(c2)C(=O)N)/[nH]c2c1cccc2"	"UOZVVPXKJGOFIG-UHFFFAOYSA-N"	"InChI=1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)"	"yes"	""	""
"9892"	"talabostat"	""	"Synthetic organic"	""	""	""	""	"363894186"	"6918572"	""	""	"CHEMBL67279"	""	""	""	""	"[(2R)-1-[(2S)-2-amino-3-methylbutanoyl]pyrrolidin-2-yl]boronic acid"	"talabostat"	"compound 1 [PMID: 18783201]|PT-100|PT100|Val-boro-pro|Val-boroPro"	"CC([C@@H](C(=O)N1CCC[C@H]1B(O)O)N)C"	"FKCMADOPPWWGNZ-YUMQZZPRSA-N"	"InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1"	"yes"	""	""
"7817"	"talmapimod"	""	"Synthetic organic"	""	""	""	""	"223366148"	"9871074"	""	""	"CHEMBL514201"	""	""	""	""	"2-[6-chloro-5-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine-1-carbonyl]-1-methylindol-3-yl]-N,N-dimethyl-2-oxoacetamide"	"talmapimod"	"SCIO 469 hydrochloride|SCIO-469"	"Fc1ccc(cc1)CN1C[C@@H](C)N(C[C@@H]1C)C(=O)c1cc2c(cn(c2cc1Cl)C)C(=O)C(=O)N(C)C"	"ZMELOYOKMZBMRB-DLBZAZTESA-N"	"InChI=1S/C27H30ClFN4O3/c1-16-13-33(17(2)12-32(16)14-18-6-8-19(29)9-7-18)26(35)21-10-20-22(25(34)27(36)30(3)4)15-31(5)24(20)11-23(21)28/h6-11,15-17H,12-14H2,1-5H3/t16-,17+/m0/s1"	"yes"	""	""
"5706"	"tamatinib"	""	"Synthetic organic"	""	""	""	""	"178102333"	"11213558"	""	""	"CHEMBL475251"	""	""	""	""	"6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]pyrimidin-4-yl]amino]-2,2-dimethyl-4H-pyrido[2,3-e][1,4]oxazin-3-one"	""	"R 406|R-406|R406 free base"	"COc1cc(Nc2ncc(c(n2)Nc2ccc3c(n2)NC(=O)C(O3)(C)C)F)cc(c1OC)OC"	"NHHQJBCNYHBUSI-UHFFFAOYSA-N"	"InChI=1S/C22H23FN6O5/c1-22(2)20(30)28-19-13(34-22)6-7-16(27-19)26-18-12(23)10-24-21(29-18)25-11-8-14(31-3)17(33-5)15(9-11)32-4/h6-10H,1-5H3,(H3,24,25,26,27,28,29,30)"	"yes"	""	""
"7751"	"tanespimycin"	""	"Synthetic organic"	""	""	""	""	"223366084"	"6440175"	""	""	"CHEMBL126955"	""	""	""	""	"[(3R,5S,6R,7S,8E,10S,11S,12E,14E)-6-hydroxy-5,11-dimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-21-(prop-2-enylamino)-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate"	"tanespimycin"	"17-AAG|17-allylamino-17-demethoxygeldanamycin|17-N-allylamino-17-demethoxygeldanamycin|17AAG|compound 4 [PMID:15978816]"	"C=CCNC1=C2C[C@@H](C)C[C@H](OC)[C@H](O)[C@@H](C)/C=C(\C)/[C@@H]([C@H](/C=C/C=C(/C(=O)NC(=CC1=O)C2=O)\C)OC)OC(=O)N"	"AYUNIORJHRXIBJ-HTLBVUBBSA-N"	"InChI=1S/C31H43N3O8/c1-8-12-33-26-21-13-17(2)14-25(41-7)27(36)19(4)15-20(5)29(42-31(32)39)24(40-6)11-9-10-18(3)30(38)34-22(28(21)37)16-23(26)35/h8-11,15-17,19,24-25,27,29,33,36H,1,12-14H2,2-7H3,(H2,32,39)(H,34,38)/b11-9+,18-10+,20-15+/t17-,19+,24+,25+,27-,29+/m1/s1"	"yes"	""	""
"9836"	"tanzisertib"	""	"Synthetic organic"	""	""	""	""	"363894130"	"11597537"	""	""	"CHEMBL1950289"	""	""	""	""	""	""	"CC-930|CC930|compound 1 [PMID: 22244937]"	"OC1CCC(CC1)Nc1ncc2c(n1)n([C@@H]1COCC1)c(n2)Nc1c(F)cc(cc1F)F"	"IBGLGMOPHJQDJB-MOKVOYLWSA-N"	"InChI=1S/C21H23F3N6O2/c22-11-7-15(23)18(16(24)8-11)28-21-27-17-9-25-20(26-12-1-3-14(31)4-2-12)29-19(17)30(21)13-5-6-32-10-13/h7-9,12-14,31H,1-6,10H2,(H,27,28)(H,25,26,29)/t12?,13-,14?/m0/s1"	"yes"	""	""
"9686"	"tapinarof"	""	"Synthetic organic"	"yes"	""	""	""	"348353645"	"6439522"	""	""	"CHEMBL259571"	""	""	""	""	"5-[(E)-2-phenylethenyl]-2-propan-2-ylbenzene-1,3-diol"	"tapinarof"	"benvitimod|GSK-2894512|GSK2894512|Vtama&reg;|WB-1001|WBI 1001|WBI-1001"	"CC(c1c(O)cc(cc1O)/C=C/c1ccccc1)C"	"ZISJNXNHJRQYJO-CMDGGOBGSA-N"	"InChI=1S/C17H18O2/c1-12(2)17-15(18)10-14(11-16(17)19)9-8-13-6-4-3-5-7-13/h3-12,18-19H,1-2H3/b9-8+"	"yes"	""	""
"9941"	"TAS05567"	""	"Synthetic organic"	""	""	""	""	"363894235"	"71543230"	""	""	""	""	""	""	""	"3-[(3-aminooxan-4-yl)amino]-5-[(2-tert-butyl-7-methyl-2H-indazol-5-yl)amino]-1,2,4-triazine-6-carboxamide"	""	""	"N[C@H]1COCC[C@H]1Nc1nnc(c(n1)Nc1cc(C)c2c(c1)cn(n2)C(C)(C)C)C(=O)N"	"ATERGQQFFHVNOJ-LSDHHAIUSA-N"	"InChI=1S/C21H29N9O2/c1-11-7-13(8-12-9-30(21(2,3)4)29-16(11)12)24-19-17(18(23)31)27-28-20(26-19)25-15-5-6-32-10-14(15)22/h7-9,14-15H,5-6,10,22H2,1-4H3,(H2,23,31)(H2,24,25,26,28)/t14-,15+/m0/s1"	"yes"	""	""
"4746"	"tauroursodeoxycholic acid"	""	"Metabolite"	"yes"	"yes"	""	""	"178101456"	"9848818"	""	""	"CHEMBL272427"	""	""	""	""	"2-[(4R)-4-[(1S,2S,5R,7S,9S,10R,11S,14R,15R)-5,9-dihydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadecan-14-yl]pentanamido]ethane-1-sulfonic acid"	"ursodoxicoltaurine"	"Relyvrio&reg; (sodium phenylbutyrate + taurursodiol)|tauroursodeoxycholate|taurursodiol|TUDA|TUDCA|UR 906|ursodoxicoltaurine (INN)"	"O[C@@H]1CC[C@]2([C@@H](C1)C[C@@H]([C@@H]1[C@@H]2CC[C@]2([C@H]1CC[C@@H]2[C@@H](CCC(=O)NCCS(=O)(=O)O)C)C)O)C"	"BHTRKEVKTKCXOH-LBSADWJPSA-N"	"InChI=1S/C26H45NO6S/c1-16(4-7-23(30)27-12-13-34(31,32)33)19-5-6-20-24-21(9-11-26(19,20)3)25(2)10-8-18(28)14-17(25)15-22(24)29/h16-22,24,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17+,18-,19-,20+,21+,22+,24+,25+,26-/m1/s1"	"yes"	""	""
"2902"	"TC14012"	""	"Peptide"	""	""	""	""	"135652600"	"16131528"	""	""	""	""	""	""	""	""	""	"TC 14012|TC-14012"	""	""	""	"yes"	""	""
"7378"	"tebentafusp"	""	"Antibody"	"yes"	""	""	""	"178103950"	""	""	""	""	""	""	""	""	""	"tebentafusp"	"IMCgp100|Kimmtrak&reg;|tebentafusp-tebn"	""	""	""	"yes"	""	""
"7049"	"teduglutide"	""	"Peptide"	"yes"	""	""	""	"178103628"	"16139605"	""	""	"CHEMBL2104987"	""	""	""	""	""	"teduglutide"	"ALX-0600|Gattex&reg;|GLP2-2G|Revestive&reg;"	"CC[C@H](C)[C@@H](C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](Cc1cnc[nH]1)N"	"CILIXQOJUNDIDU-ASQIGDHWSA-N"	"InChI=1S/C164H252N44O55S/c1-21-77(11)126(156(255)187-95(44-46-114(167)214)141(240)206-130(83(17)211)160(259)186-93(42-33-34-49-165)140(239)202-129(80(14)24-4)159(258)208-131(84(18)212)161(260)200-111(163(262)263)66-125(230)231)203-151(250)100(54-76(9)10)189-145(244)103(57-88-67-175-92-41-32-31-40-90(88)92)192-147(246)105(60-116(169)216)199-157(256)127(78(12)22-2)204-152(251)102(56-87-38-29-26-30-39-87)190-149(248)109(64-123(226)227)195-137(236)94(43-35-50-174-164(171)172)183-134(233)82(16)179-133(232)81(15)180-142(241)98(52-74(5)6)188-146(245)104(59-115(168)215)194-150(249)110(65-124(228)229)196-143(242)99(53-75(7)8)198-158(257)128(79(13)23-3)205-162(261)132(85(19)213)207-153(252)106(61-117(170)217)193-139(238)97(48-51-264-20)185-138(237)96(45-47-120(220)221)184-148(247)108(63-122(224)225)197-155(254)113(72-210)201-144(243)101(55-86-36-27-25-28-37-86)191-154(253)112(71-209)182-119(219)70-177-136(235)107(62-121(222)223)181-118(218)69-176-135(234)91(166)58-89-68-173-73-178-89/h25-32,36-41,67-68,73-85,91,93-113,126-132,175,209-213H,21-24,33-35,42-66,69-72,165-166H2,1-20H3,(H2,167,214)(H2,168,215)(H2,169,216)(H2,170,217)(H,173,178)(H,176,234)(H,177,235)(H,179,232)(H,180,241)(H,181,218)(H,182,219)(H,183,233)(H,184,247)(H,185,237)(H,186,259)(H,187,255)(H,188,245)(H,189,244)(H,190,248)(H,191,253)(H,192,246)(H,193,238)(H,194,249)(H,195,236)(H,196,242)(H,197,254)(H,198,257)(H,199,256)(H,200,260)(H,201,243)(H,202,239)(H,203,250)(H,204,251)(H,205,261)(H,206,240)(H,207,252)(H,208,258)(H,220,221)(H,222,223)(H,224,225)(H,226,227)(H,228,229)(H,230,231)(H,262,263)(H4,171,172,174)/t77-,78-,79-,80-,81-,82-,83+,84+,85+,91-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,126-,127-,128-,129-,130-,131-,132-/m0/s1"	"yes"	""	""
"14508"	"tegoprubart"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"tegoprubart"	"AT-1501|AT1501"	""	""	""	"yes"	""	""
"11827"	"telitacicept"	""	"Peptide"	"yes"	""	""	""	"461663383"	""	""	""	""	""	""	""	""	""	"telitacicept"	"RC-18|RC18|Tai'ai&reg;"	""	""	""	"yes"	""	""
"9490"	"telotristat ethyl"	""	"Synthetic organic"	"yes"	""	""	""	"329968430"	"25181577"	""	""	"CHEMBL2105695"	""	""	""	""	"ethyl (2S)-2-amino-3-[4-[2-amino-6-[(1R)-1-[4-chloro-2-(3-methylpyrazol-1-yl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]propanoate"	"telotristat"	"LX-1606|LX1606|Xermelo&reg;"	"CCOC(=O)[C@H](Cc1ccc(cc1)c1cc(nc(n1)N)O[C@@H](C(F)(F)F)c1ccc(cc1n1ccc(n1)C)Cl)N"	"MDSQOJYHHZBZKA-GBXCKJPGSA-N"	"InChI=1S/C27H26ClF3N6O3/c1-3-39-25(38)20(32)12-16-4-6-17(7-5-16)21-14-23(35-26(33)34-21)40-24(27(29,30)31)19-9-8-18(28)13-22(19)37-11-10-15(2)36-37/h4-11,13-14,20,24H,3,12,32H2,1-2H3,(H2,33,34,35)/t20-,24+/m0/s1"	"yes"	""	""
"11530"	"temelimab"	""	"Antibody"	""	""	""	""	"441604902"	""	""	""	""	""	""	""	""	""	"temelimab"	"GNbAC1"	""	""	""	"yes"	""	""
"9907"	"tenalisib"	""	"Synthetic organic"	""	""	""	""	"363894201"	"86291103"	""	""	""	""	""	""	""	"3-(3-fluorophenyl)-2-[(1S)-1-[(9H-purin-6-yl)amino]propyl]-4H-chromen-4-one"	"tenalisib"	"RP-6530|RP6530"	"CC[C@@H](c1oc2ccccc2c(=O)c1c1cccc(c1)F)Nc1ncnc2c1[nH]cn2"	"HDXDQPRPFRKGKZ-INIZCTEOSA-N"	"InChI=1S/C23H18FN5O2/c1-2-16(29-23-19-22(26-11-25-19)27-12-28-23)21-18(13-6-5-7-14(24)10-13)20(30)15-8-3-4-9-17(15)31-21/h3-12,16H,2H2,1H3,(H2,25,26,27,28,29)/t16-/m0/s1"	"yes"	""	""
"9906"	"teneligliptin"	""	"Synthetic organic"	"yes"	""	""	""	"363894200"	"11949652"	""	""	"CHEMBL2147777"	""	""	""	""	"[(2S,4S)-4-[4-(5-methyl-2-phenylpyrazol-3-yl)piperazin-1-yl]pyrrolidin-2-yl]-(1,3-thiazolidin-3-yl)methanone"	"teneligliptin"	"compound 8g [PMID: 22959556]|MP-513|MP513|Teneli"	"O=C(N1CSCC1)[C@H]1NC[C@H](C1)N1CCN(CC1)c1cc(nn1c1ccccc1)C"	"WGRQANOPCQRCME-PMACEKPBSA-N"	"InChI=1S/C22H30N6OS/c1-17-13-21(28(24-17)18-5-3-2-4-6-18)26-9-7-25(8-10-26)19-14-20(23-15-19)22(29)27-11-12-30-16-27/h2-6,13,19-20,23H,7-12,14-16H2,1H3/t19-,20-/m0/s1"	"yes"	""	""
"9770"	"tepilamide fumarate"	""	"Synthetic organic"	""	""	""	""	"354702243"	"46179632"	""	""	""	""	""	""	""	"4-O-[2-(diethylamino)-2-oxoethyl] 1-O-methyl (E)-but-2-enedioate"	"tepilamide fumarate"	"XP 23829|XP-23829|XP23829"	"CCN(C(=O)COC(=O)/C=C/C(=O)OC)CC"	"AKUGRXRLHCCENI-VOTSOKGWSA-N"	"InChI=1S/C11H17NO5/c1-4-12(5-2)9(13)8-17-11(15)7-6-10(14)16-3/h6-7H,4-5,8H2,1-3H3/b7-6+"	"yes"	""	""
"12252"	"teplizumab"	""	"Antibody"	"yes"	""	""	""	"473153840"	""	""	""	""	""	""	""	""	""	"teplizumab"	"humanized OKT3|MGA031|PRV-031|teplizumab-mzwv|Tzield&reg;"	""	""	""	"yes"	""	""
"10353"	"tepoditamab"	""	"Antibody"	""	""	""	""	"384403634"	""	""	""	""	""	""	""	""	""	"tepoditamab"	"MCLA-117|MCLA117|PB9122"	""	""	""	"yes"	""	""
"10555"	"TEPP-46"	""	"Synthetic organic"	""	""	""	""	"404859003"	"44246499"	""	""	"CHEMBL1085588"	""	""	""	""	""	""	"compound 46 [PMID: 20451379]|ML-265|ML265|TEPP46"	"Nc1cccc(c1)Cn1ncc2c(c1=O)n(C)c1c2sc(c1)S(=O)C"	"ZWKJWVSEDISQIS-UHFFFAOYSA-N"	"InChI=1S/C17H16N4O2S2/c1-20-13-7-14(25(2)23)24-16(13)12-8-19-21(17(22)15(12)20)9-10-4-3-5-11(18)6-10/h3-8H,9,18H2,1-2H3"	"yes"	""	""
"10612"	"teprotumumab"	""	"Antibody"	"yes"	""	""	""	"404859059"	""	""	""	""	""	""	""	""	""	"teprotumumab"	"R1507|RG-1507|RG1507|RV 001|RV-001|Tepezza&reg;|teprotumumab-trbw"	""	""	""	"yes"	""	""
"2608"	"terfenadine"	""	"Synthetic organic"	"yes"	"yes"	""	""	"135651245"	"5405"	""	""	"CHEMBL17157"	""	""	""	""	"1-(4-tert-butylphenyl)-4-[4-[hydroxy-di(phenyl)methyl]piperidin-1-yl]butan-1-ol"	"terfenadine"	"RMI-9918|Seldane&reg;|Triludan&reg;"	"OC(c1ccc(cc1)C(C)(C)C)CCCN1CCC(CC1)C(c1ccccc1)(c1ccccc1)O"	"GUGOEEXESWIERI-UHFFFAOYSA-N"	"InChI=1S/C32H41NO2/c1-31(2,3)26-18-16-25(17-19-26)30(34)15-10-22-33-23-20-29(21-24-33)32(35,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-14,16-19,29-30,34-35H,10,15,20-24H2,1-3H3"	"yes"	""	""
"6844"	"teriflunomide"	""	"Synthetic organic"	"yes"	""	""	""	"178103450"	"54684141"	""	""	"CHEMBL973"	""	""	""	""	"(Z)-2-cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]but-2-enamide"	"teriflunomide"	"A77 1726|Aubagio&reg;|flucyamide|HMR-1726"	"N#C/C(=C(/O)\C)/C(=O)Nc1ccc(cc1)C(F)(F)F"	"UTNUDOFZCWSZMS-YFHOEESVSA-N"	"InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-"	"yes"	""	""
"9784"	"tethered chemerin 9"	""	"Peptide"	""	""	""	""	"354702257"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"9877"	"tetomilast"	""	"Synthetic organic"	""	""	""	""	"363894171"	"3025803"	""	""	"CHEMBL332750"	""	""	""	""	"6-[2-(3,4-diethoxyphenyl)-1,3-thiazol-4-yl]pyridine-2-carboxylic acid"	"tetomilast"	"compound 19f [PMID: 7830278]|OPC-6535|OPC6535"	"CCOc1cc(ccc1OCC)c1scc(n1)c1cccc(n1)C(=O)O"	"XDBHURGONHZNJF-UHFFFAOYSA-N"	"InChI=1S/C19H18N2O4S/c1-3-24-16-9-8-12(10-17(16)25-4-2)18-21-15(11-26-18)13-6-5-7-14(20-13)19(22)23/h5-11H,3-4H2,1-2H3,(H,22,23)"	"yes"	""	""
"8933"	"tezepelumab"	""	"Antibody"	"yes"	""	""	""	"310264714"	""	""	""	""	""	""	""	""	""	"tezepelumab"	"AMG 157|AMG-157|MEDI-9929|MEDI9929|tezepelumab-ekko|Tezspire&reg;"	""	""	""	"yes"	""	""
"10603"	"TG11-77"	""	"Synthetic organic"	""	""	""	""	"404859050"	"145996528"	""	""	""	""	""	""	""	"2-((4,6-Dimethylpyridin-2-yl)amino)-N-(2-(2-methyl-1H-indol-3-yl)ethyl)pyrimidine-5-carboxamide"	""	"compound 20o [PMID: 31904232]"	"Cc1cc(Nc2ncc(cn2)C(=O)NCCc2c(C)[nH]c3c2cccc3)nc(c1)C"	"NZOAMVGASFFEJH-UHFFFAOYSA-N"	"InChI=1S/C23H24N6O/c1-14-10-15(2)27-21(11-14)29-23-25-12-17(13-26-23)22(30)24-9-8-18-16(3)28-20-7-5-4-6-19(18)20/h4-7,10-13,28H,8-9H2,1-3H3,(H,24,30)(H,25,26,27,29)"	"yes"	""	""
"9283"	"TG6-129"	""	"Synthetic organic"	""	""	""	""	"318164802"	"1987175"	""	""	"CHEMBL1372836"	""	""	""	""	""	""	""	"CCc1nnc(s1)NS(=O)(=O)c1ccc(cc1)NC(=S)NC(=O)/C=C/c1ccc(cc1)F"	"SYSMVOANBVDZNG-LFYBBSHMSA-N"	"InChI=1S/C20H18FN5O3S3/c1-2-18-24-25-20(31-18)26-32(28,29)16-10-8-15(9-11-16)22-19(30)23-17(27)12-5-13-3-6-14(21)7-4-13/h3-12H,2H2,1H3,(H,25,26)(H2,22,23,27,30)/b12-5+"	"yes"	""	""
"12520"	"TG8-260"	""	"Synthetic organic"	""	""	""	""	"479821310"	"155128767"	""	""	""	""	""	""	""	"4-(1H-imidazol-5-yl)-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide"	""	"compound 2f [PMID: 35187419]|TG8260"	"CC1=C(CCNC(=O)C2=CC=C(C=C2)C3=CNC=N3)C4=C(N1)C=CC=C4"	"XMWMPTMQNJXLNV-UHFFFAOYSA-N"	"InChI=1S/C21H20N4O/c1-14-17(18-4-2-3-5-19(18)25-14)10-11-23-21(26)16-8-6-15(7-9-16)20-12-22-13-24-20/h2-9,12-13,25H,10-11H2,1H3,(H,22,24)(H,23,26)"	"yes"	""	""
"5060"	"TGF&beta;1"	"Human"	"Peptide"	""	""	""	""	"178101753"	""	"P01137"	"ENSG00000105329"	""	""	""	""	""	""	""	"TGF-beta-1|transforming growth factor beta-1"	""	""	""	"yes"	""	""
"10184"	"TH5487"	""	"Synthetic organic"	""	""	""	""	"381118894"	"137321164"	""	""	""	""	""	""	""	""	""	"TH-5487"	"Ic1ccc(cc1)NC(=O)N1CCC(CC1)n1c(=O)[nH]c2c1cccc2Br"	"FZLKVWWPFOLPKF-UHFFFAOYSA-N"	"InChI=1S/C19H18BrIN4O2/c20-15-2-1-3-16-17(15)23-19(27)25(16)14-8-10-24(11-9-14)18(26)22-13-6-4-12(21)5-7-13/h1-7,14H,8-11H2,(H,22,26)(H,23,27)"	"yes"	""	""
"7327"	"thalidomide"	""	"Synthetic organic"	"yes"	""	""	""	"178103899"	"5426"	""	""	"CHEMBL468"	""	""	""	""	"2-(6-hydroxy-2-oxo-2,3,4,5-tetrahydropyridin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione"	"thalidomide"	"K-17"	"OC1=NC(=O)C(CC1)N1C(=O)c2c(C1=O)cccc2"	"UEJJHQNACJXSKW-UHFFFAOYSA-N"	"InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)"	"yes"	""	""
"413"	"theophylline"	""	"Natural product"	"yes"	""	""	""	"135651254"	"2153"	""	""	"CHEMBL190"	""	""	""	""	"1,3-dimethyl-7H-purine-2,6-dione"	"aminophylline|choline theophyllinate|guaifylline"	"Nuelin&reg;|Slo-Bid&reg;|Theolair&reg;"	"Cn1c(=O)n(C)c2c(c1=O)[nH]cn2"	"ZFXYFBGIUFBOJW-UHFFFAOYSA-N"	"InChI=1S/C7H8N4O2/c1-10-5-4(8-3-9-5)6(12)11(2)7(10)13/h3H,1-2H3,(H,8,9)"	"yes"	""	""
"13047"	"thrombospondin 1"	"Human"	"Peptide"	""	""	""	""	"491299829"	""	"P07996"	"ENSG00000137801"	""	""	""	""	""	""	""	"THBS-1|TSP-1|TSP1"	""	""	""	"yes"	""	""
"5083"	"thymic stromal lymphopoietin"	"Human"	"Peptide"	""	""	""	""	"178101776"	""	"Q969D9"	"ENSG00000145777"	""	""	""	""	""	""	""	"TSLP"	""	""	""	"yes"	""	""
"10350"	"tibulizumab"	""	"Antibody"	""	""	""	""	"384403631"	""	""	""	""	""	""	""	""	""	"tibulizumab"	"LY-3090106|LY3090106"	""	""	""	"yes"	""	""
"13505"	"tigemocoxib"	""	"Synthetic organic"	""	""	""	""	"500839915"	"9858913"	""	""	"CHEMBL1230209"	""	""	""	""	"(2S)-7-tert-butyl-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid"	"tigemocoxib"	"29b-(S) [PMID: 20709553]|SC-75416|SC75416"	"CC(C)(C)C1=C(C=C2C=C([C@H](OC2=C1)C(F)(F)F)C(=O)O)Cl"	"QGCKNIAMHUUUDI-LBPRGKRZSA-N"	"InChI=1S/C15H14ClF3O3/c1-14(2,3)9-6-11-7(5-10(9)16)4-8(13(20)21)12(22-11)15(17,18)19/h4-6,12H,1-3H3,(H,20,21)/t12-/m0/s1"	"yes"	""	""
"8093"	"tildrakizumab"	""	"Antibody"	"yes"	""	""	""	"249565773"	""	""	""	""	""	""	""	""	""	"tildrakizumab"	"Ilumetri&reg;|Ilumya&reg;|MK-3222|MK3222|SCH-900222|SCH900222|SUNPG1623|tildrakizumab-asmn"	""	""	""	"yes"	""	""
"9277"	"timapiprant"	""	"Synthetic organic"	""	""	""	""	"318164796"	"11462174"	""	""	"CHEMBL560993"	""	""	""	""	"2-[5-fluoro-2-methyl-3-(quinolin-2-ylmethyl)indol-1-yl]acetic acid"	"timapiprant"	"OC000459|OC459"	"Fc1ccc2c(c1)c(Cc1ccc3c(n1)cccc3)c(n2CC(=O)O)C"	"FATGTHLOZSXOBC-UHFFFAOYSA-N"	"InChI=1S/C21H17FN2O2/c1-13-17(11-16-8-6-14-4-2-3-5-19(14)23-16)18-10-15(22)7-9-20(18)24(13)12-21(25)26/h2-10H,11-12H2,1H3,(H,25,26)"	"yes"	""	""
"9097"	"timolumab"	""	"Antibody"	""	""	""	""	"315661182"	""	""	""	""	""	""	""	""	""	"timolumab"	"8c10|BTT-1023|BTT1023|r8c10|SI-3106|SI-636"	""	""	""	"yes"	""	""
"367"	"tiotropium"	""	"Synthetic organic"	"yes"	""	""	""	"135651266"	"5487427"	""	""	"CHEMBL3305968"	""	""	""	""	"(1R,2R,4S,5S)-7-{[2-hydroxy-2,2-bis(thiophen-2-yl)acetyl]oxy}-9,9-dimethyl-3-oxa-9-azatricyclo[3.3.1.0^{2,4}]nonan-9-ium"	"tiotropium bromide"	"BA-679-BR|Spiriva&reg;"	"O=C(C(c1cccs1)(c1cccs1)O)OC1C[C@@H]2[C@@H]3[C@H]([C@H](C1)[N+]2(C)C)O3"	"LERNTVKEWCAPOY-FPISHFTHSA-N"	"InChI=1S/C19H22NO4S2/c1-20(2)12-9-11(10-13(20)17-16(12)24-17)23-18(21)19(22,14-5-3-7-25-14)15-6-4-8-26-15/h3-8,11-13,16-17,22H,9-10H2,1-2H3/q+1/t11?,12-,13+,16-,17+"	"yes"	""	""
"12892"	"tipasertideg"	""	"Synthetic organic"	""	""	""	""	"485206013"	"146599824"	""	""	""	""	""	""	""	"N-[3-(difluoromethyl)-1-[4-[[4-[3-[1-(2,6-dioxopiperidin-3-yl)-3-methyl-2-oxobenzimidazol-4-yl]prop-2-ynoxy]piperidin-1-yl]methyl]cyclohexyl]pyrazol-4-yl]-5-[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrazolo[1,5-a]pyrimidine-3-carboxamide"	"tipasertideg"	"Compound A [WO2022174269A1]|KT-474|KT474"	"CN1C2=C(C=CC=C2N(C1=O)C3CCC(=O)NC3=O)C#CCOC4CCN(CC4)CC5CCC(CC5)N6C=C(C(=N6)C(F)F)NC(=O)C7=C8N=C(C=CN8N=C7)N9C[C@H]%10C[C@@H]9CO%10"	"NQGKNAVUMAHSQN-PKIOHZLWSA-N"	"InChI=1S/C44H49F2N11O6/c1-52-39-27(4-2-6-34(39)57(44(52)61)35-11-12-37(58)50-43(35)60)5-3-19-62-30-13-16-53(17-14-30)22-26-7-9-28(10-8-26)56-24-33(38(51-56)40(45)46)48-42(59)32-21-47-55-18-15-36(49-41(32)55)54-23-31-20-29(54)25-63-31/h2,4,6,15,18,21,24,26,28-31,35,40H,7-14,16-17,19-20,22-23,25H2,1H3,(H,48,59)(H,50,58,60)/t26?,28?,29-,31-,35?/m1/s1"	"yes"	""	""
"9265"	"tirabrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"315661340"	"54755438"	""	""	"CHEMBL4071161"	""	""	""	""	"6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one"	"tirabrutinib"	"GS-4059|ONO-4059|ONO4059|Velexbru&reg;"	"CC#CC(=O)N1CC[C@H](C1)n1c(=O)n(c2c1ncnc2N)c1ccc(cc1)Oc1ccccc1"	"SEJLPXCPMNSRAM-GOSISDBHSA-N"	"InChI=1S/C25H22N6O3/c1-2-6-21(32)29-14-13-18(15-29)31-24-22(23(26)27-16-28-24)30(25(31)33)17-9-11-20(12-10-17)34-19-7-4-3-5-8-19/h3-5,7-12,16,18H,13-15H2,1H3,(H2,26,27,28)/t18-/m1/s1"	"yes"	""	""
"9592"	"tislelizumab"	""	"Antibody"	"yes"	""	""	""	"340590223"	""	""	""	""	""	""	""	""	""	"tislelizumab"	"Bai Zean&reg;|BGB-A317|BGBA317|hu317-1/IgG4mt2|Tevimbra&reg;|tislelizumab-jsgr"	""	""	""	"yes"	""	""
"9556"	"TK05"	""	"Synthetic organic"	""	""	""	""	"336446942"	"53385780"	""	""	""	""	""	""	""	"5-[5-[4-chloro-N-(cyclopropylmethyl)anilino]pyridine-2-carbonyl]-2-(4-methoxybenzoyl)benzoic acid"	""	""	"COc1ccc(cc1)C(=O)c1ccc(cc1C(=O)O)C(=O)c1ccc(cn1)N(c1ccc(cc1)Cl)CC1CC1"	"GRDDFJXOEAJYCT-UHFFFAOYSA-N"	"InChI=1S/C31H25ClN2O5/c1-39-25-12-4-20(5-13-25)29(35)26-14-6-21(16-27(26)31(37)38)30(36)28-15-11-24(17-33-28)34(18-19-2-3-19)23-9-7-22(32)8-10-23/h4-17,19H,2-3,18H2,1H3,(H,37,38)"	"yes"	""	""
"5071"	"TL1A"	"Human"	"Peptide"	""	""	""	""	"178101764"	""	"O95150"	"ENSG00000181634"	""	""	""	""	""	""	""	"Tumor necrosis factor ligand superfamily member 15, membrane form"	""	""	""	"yes"	""	""
"5072"	"TL6"	"Human"	"Peptide"	""	""	""	""	"178101765"	""	"Q9UNG2"	"ENSG00000120337"	""	""	""	""	""	""	""	"activation-inducible TNF-related ligand|glucocorticoid- induced TNF-related ligand"	""	""	""	"yes"	""	""
"1905"	"TM30089"	""	"Synthetic organic"	""	""	""	""	"135650058"	"11384493"	""	""	"CHEMBL1643768"	""	""	""	""	"2-[3-[(4-fluorophenyl)sulfonyl-methylamino]-1,2,3,4-tetrahydrocarbazol-9-yl]acetic acid"	""	"CAY 10471|CAY-10471|CAY10471"	"OC(=O)Cn1c2CCC(Cc2c2c1cccc2)N(S(=O)(=O)c1ccc(cc1)F)C"	"CANCTKXGRVNXFP-UHFFFAOYSA-N"	"InChI=1S/C21H21FN2O4S/c1-23(29(27,28)16-9-6-14(22)7-10-16)15-8-11-20-18(12-15)17-4-2-3-5-19(17)24(20)13-21(25)26/h2-7,9-10,15H,8,11-13H2,1H3,(H,25,26)"	"yes"	""	""
"6881"	"tocilizumab"	""	"Antibody"	"yes"	""	""	""	"178103463"	""	""	""	""	""	""	""	""	""	"tocilizumab"	"Actemra&reg;|R-1569|RG-1569|RHPM-1|RoActemra&reg;"	""	""	""	"yes"	""	""
"13467"	"toddacoumalone"	""	"Natural product"	""	""	""	""	"500839877"	"86302487"	""	""	"CHEMBL5170835"	""	""	""	""	"(2R,4S)-2-[(E)-2-(5,7-dimethoxy-2-oxochromen-8-yl)ethenyl]-2,6-dimethyl-4-(2-methylprop-1-enyl)-3,4-dihydropyrano[3,2-c]quinolin-5-one"	""	"compound 8 [PMID: 24597921]"	"COC1=CC(OC)=C(/C=C/[C@@]2(C)C[C@@H](C=C(C)C)C3=C(O2)C4=CC=CC=C4N(C)C3=O)C5=C1C=CC(=O)O5"	"IOVBMEHJQSKXAU-CSLHTZHMSA-N"	"InChI=1S/C31H31NO6/c1-18(2)15-19-17-31(3,38-29-20-9-7-8-10-23(20)32(4)30(34)27(19)29)14-13-22-25(36-6)16-24(35-5)21-11-12-26(33)37-28(21)22/h7-16,19H,17H2,1-6H3/b14-13+/t19-,31+/m1/s1"	"yes"	""	""
"5677"	"tofacitinib"	""	"Synthetic organic"	"yes"	""	""	""	"178102304"	"9926791"	""	""	"CHEMBL221959"	""	""	""	""	"3-[(3R,4R)-4-methyl-3-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]piperidin-1-yl]-3-oxopropanenitrile"	"tofacitinib"	"CP-690,550|CP-690550|tasocitinib|Xeljanz&reg;"	"N#CCC(=O)N1CC[C@H]([C@H](C1)N(c1ncnc2c1cc[nH]2)C)C"	"UJLAWZDWDVHWOW-YPMHNXCESA-N"	"InChI=1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13+/m1/s1"	"yes"	""	""
"10625"	"tolebrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"404859072"	"124111565"	""	""	""	""	""	""	""	"4-amino-3-(4-phenoxyphenyl)-1-[(3R)-1-prop-2-enoylpiperidin-3-yl]imidazo[4,5-c]pyridin-2-one"	"tolebrutinib"	"BTK'168|Cenrifki&reg;|example 3 [WO2016196840A1]|PRN-2246|PRN2246|SAR442168"	"C=CC(=O)N1CCC[C@H](C1)n1c(=O)n(c2c1ccnc2N)c1ccc(cc1)Oc1ccccc1"	"KOEUOFPEZFUWRF-LJQANCHMSA-N"	"InChI=1S/C26H25N5O3/c1-2-23(32)29-16-6-7-19(17-29)30-22-14-15-28-25(27)24(22)31(26(30)33)18-10-12-21(13-11-18)34-20-8-4-3-5-9-20/h2-5,8-15,19H,1,6-7,16-17H2,(H2,27,28)/t19-/m1/s1"	"yes"	""	""
"7311"	"tolmetin"	""	"Synthetic organic"	"yes"	""	""	""	"178103884"	"5509"	""	""	"CHEMBL1020"	""	""	""	""	"2-[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid"	"tolmetin"	"MCN-2559|McN-2559-21-98|Tolectin&reg;"	"OC(=O)Cc1ccc(n1C)C(=O)c1ccc(cc1)C"	"UPSPUYADGBWSHF-UHFFFAOYSA-N"	"InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18)"	"yes"	""	""
"9408"	"tomaralimab"	""	"Antibody"	""	""	""	""	"328083510"	""	""	""	""	""	""	""	""	""	"tomaralimab"	"OPN-305|OPN305|VK5A/H4"	""	""	""	"yes"	""	""
"10167"	"tomivosertib"	""	"Synthetic organic"	""	""	""	""	"381118877"	"118598754"	""	""	""	""	""	""	""	"6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione"	"tomivosertib"	"compound 23 [PMID: 29526098]|eFT-508|eFT508"	"Nc1ncnc(c1)Nc1cc(C)c2n(c1=O)C1(CCCCC1)NC2=O"	"HKTBYUWLRDZAJK-UHFFFAOYSA-N"	"InChI=1S/C17H20N6O2/c1-10-7-11(21-13-8-12(18)19-9-20-13)16(25)23-14(10)15(24)22-17(23)5-3-2-4-6-17/h7-9H,2-6H2,1H3,(H,22,24)(H3,18,19,20,21)"	"yes"	""	""
"9276"	"toreforant"	""	"Synthetic organic"	""	""	""	""	"318164795"	"23650961"	""	""	"CHEMBL3301609"	""	""	""	""	"5-(4,6-dimethyl-1H-benzimidazol-2-yl)-4-methyl-N-[3-(1-methylpiperidin-4-yl)propyl]pyrimidin-2-amine"	"toreforant"	"JNJ-38518168"	"CN1CCC(CC1)CCCNc1ncc(c(n1)C)c1nc2c([nH]1)cc(cc2C)C"	"FCRFVPZAXGJLPW-UHFFFAOYSA-N"	"InChI=1S/C23H32N6/c1-15-12-16(2)21-20(13-15)27-22(28-21)19-14-25-23(26-17(19)3)24-9-5-6-18-7-10-29(4)11-8-18/h12-14,18H,5-11H2,1-4H3,(H,27,28)(H,24,25,26)"	"yes"	""	""
"12989"	"toripalimab"	""	"Antibody"	"yes"	""	""	""	"485206110"	""	""	""	""	""	""	""	""	""	"toripalimab"	"JS-001|JS001|Loqtorzi&reg;|toripalimab-tpzi"	""	""	""	"yes"	""	""
"6781"	"tositumomab"	""	"Antibody"	"yes"	"yes"	""	""	"178103387"	""	""	""	""	""	""	""	""	""	"tositumomab"	"Bexxar&reg;|V10XA53"	""	""	""	"yes"	""	""
"12964"	"tozorakimab"	""	"Antibody"	""	""	""	""	"485206085"	""	""	""	""	""	""	""	""	""	"tozorakimab"	"MEDI-3506|MEDI3506"	""	""	""	"yes"	""	""
"9278"	"tradipitant"	""	"Synthetic organic"	"yes"	""	""	""	"318164797"	"9916461"	""	""	""	""	""	""	""	"[2-[1-[[3,5-bis(trifluoromethyl)phenyl]methyl]-5-pyridin-4-yltriazol-4-yl]pyridin-3-yl]-(2-chlorophenyl)methanone"	"tradipitant"	"LY-686017|LY686017|VLY-686|VLY686"	"Clc1ccccc1C(=O)c1cccnc1c1nnn(c1c1ccncc1)Cc1cc(cc(c1)C(F)(F)F)C(F)(F)F"	"CAVRKWRKTNINFF-UHFFFAOYSA-N"	"InChI=1S/C28H16ClF6N5O/c29-22-6-2-1-4-20(22)26(41)21-5-3-9-37-23(21)24-25(17-7-10-36-11-8-17)40(39-38-24)15-16-12-18(27(30,31)32)14-19(13-16)28(33,34)35/h1-14H,15H2"	"yes"	""	""
"8001"	"tralokinumab"	""	"Antibody"	"yes"	""	""	""	"249565681"	""	""	""	""	""	""	""	""	""	"tralokinumab"	"Adbry&reg;|Adtralza&reg;|BAK1.1|CAT-354|tralokinumab-ldrm"	""	""	""	"yes"	""	""
"2336"	"TRAM-34"	""	"Synthetic organic"	""	""	""	""	"135651273"	"656734"	""	""	"CHEMBL498270"	""	""	""	""	"1-[(2-chlorophenyl)-di(phenyl)methyl]pyrazole"	""	""	"Clc1ccccc1C(n1cccn1)(c1ccccc1)c1ccccc1"	"KBFUQFVFYYBHBT-UHFFFAOYSA-N"	"InChI=1S/C22H17ClN2/c23-21-15-8-7-14-20(21)22(25-17-9-16-24-25,18-10-3-1-4-11-18)19-12-5-2-6-13-19/h1-17H"	"yes"	""	""
"6326"	"tranilast"	""	"Synthetic organic"	"yes"	""	""	""	"178102944"	"5282230"	""	""	"CHEMBL415324"	""	""	""	""	"2-[3-(3,4-dimethoxyphenyl)prop-2-enoylamino]benzoic acid"	"tranilast"	"MK-341|SB-252218"	"COc1cc(/C=C/C(=O)Nc2ccccc2C(=O)O)ccc1OC"	"NZHGWWWHIYHZNX-CSKARUKUSA-N"	"InChI=1S/C18H17NO5/c1-23-15-9-7-12(11-16(15)24-2)8-10-17(20)19-14-6-4-3-5-13(14)18(21)22/h3-11H,1-2H3,(H,19,20)(H,21,22)/b10-8+"	"yes"	""	""
"9864"	"tregalizumab"	""	"Antibody"	""	""	""	""	"363894158"	""	""	""	""	""	""	""	""	""	"tregalizumab"	"BT-061|hB-F5"	""	""	""	"yes"	""	""
"8462"	"tremelimumab"	""	"Antibody"	"yes"	""	""	""	"252166672"	""	""	""	""	""	""	""	""	""	"tremelimumab"	"CP-675|CP-675,206|CP-675206|Imjudo&reg;|ticilimumab|tremelimumab-actl"	""	""	""	"yes"	""	""
"2870"	"triamcinolone"	""	"Synthetic organic"	"yes"	""	""	""	"135651276"	"31307"	""	""	"CHEMBL1451"	""	""	""	""	"(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one"	"triamcinolone"	"fluoxiprednisolone|Kenalog&reg;|Nasacort&reg;"	"OCC(=O)[C@@]1(O)[C@H](O)C[C@@H]2[C@]1(C)C[C@H](O)[C@]1([C@H]2CCC2=CC(=O)C=C[C@]12C)F"	"GFNANZIMVAIWHM-OBYCQNJPSA-N"	"InChI=1S/C21H27FO6/c1-18-6-5-12(24)7-11(18)3-4-13-14-8-15(25)21(28,17(27)10-23)19(14,2)9-16(26)20(13,18)22/h5-7,13-16,23,25-26,28H,3-4,8-10H2,1-2H3/t13-,14-,15+,16-,18-,19-,20-,21-/m0/s1"	"yes"	""	""
"2867"	"triamcinolone acetonide"	""	"Synthetic organic"	"yes"	""	""	""	"135651277"	"6436"	""	""	"CHEMBL1504"	""	""	""	""	"(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-4b-fluoro-5-hydroxy-6b-(hydroxyacetyl)-4a,6a,8,8-tetramethyl-4a,4b,5,6,6a,6b,9a,10,10a,10b,11,12-dodecahydro-2H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-2-one"	""	"Zilretta&reg;"	"OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1CCC1=CC(=O)C=C[C@]21C)F)(C)C"	"YNDXUCZADRHECN-JNQJZLCISA-N"	"InChI=1S/C24H31FO6/c1-20(2)30-19-10-16-15-6-5-13-9-14(27)7-8-21(13,3)23(15,25)17(28)11-22(16,4)24(19,31-20)18(29)12-26/h7-9,15-17,19,26,28H,5-6,10-12H2,1-4H3/t15-,16-,17-,19+,21-,22-,23-,24+/m0/s1"	"yes"	""	""
"9962"	"trifarotene"	""	"Synthetic organic"	"yes"	""	""	""	"374883849"	"11518241"	""	""	"CHEMBL3707313"	""	""	""	""	"4-[3-(3-tert-butyl-4-pyrrolidin-1-ylphenyl)-4-(2-hydroxyethoxy)phenyl]benzoic acid"	"trifarotene"	"Aklief&reg;|CD5789|compound 15b [PMID: 29706423]"	"OCCOc1ccc(cc1c1ccc(c(c1)C(C)(C)C)N1CCCC1)c1ccc(cc1)C(=O)O"	"MFBCDACCJCDGBA-UHFFFAOYSA-N"	"InChI=1S/C29H33NO4/c1-29(2,3)25-19-23(10-12-26(25)30-14-4-5-15-30)24-18-22(11-13-27(24)34-17-16-31)20-6-8-21(9-7-20)28(32)33/h6-13,18-19,31H,4-5,14-17H2,1-3H3,(H,32,33)"	"yes"	""	""
"9626"	"trilaciclib"	""	"Synthetic organic"	"yes"	""	""	""	"340590256"	"68029831"	""	""	""	""	""	""	""	"2-[[5-(4-methylpiperazin-1-yl)pyridin-2-yl]amino]spiro[7,8-dihydropyrazino[5,6]pyrrolo[1,2-d]pyrimidine-9,1'-cyclohexane]-6-one"	"trilaciclib"	"Cosela&reg;|G1T28"	"CN1CCN(CC1)c1ccc(nc1)Nc1ncc2c(n1)n1c(c2)C(=O)NCC21CCCCC2"	"PDGKHKMBHVFCMG-UHFFFAOYSA-N"	"InChI=1S/C24H30N8O/c1-30-9-11-31(12-10-30)18-5-6-20(25-15-18)28-23-26-14-17-13-19-22(33)27-16-24(7-3-2-4-8-24)32(19)21(17)29-23/h5-6,13-15H,2-4,7-12,16H2,1H3,(H,27,33)(H,25,26,28,29)"	"yes"	""	""
"13073"	"trilobatin"	""	"Natural product"	""	""	""	""	"491299855"	"6451798"	""	""	"CHEMBL514177"	""	""	""	""	"1-[2,6-dihydroxy-4-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-3-(4-hydroxyphenyl)propan-1-one"	""	"phloretin-4'-O-glucoside|prunin dihydrochalcone"	"C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O)O"	"GSTCPEBQYSOEHV-QNDFHXLGSA-N"	"InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-12-7-14(25)17(15(26)8-12)13(24)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-23,25-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1"	"yes"	""	""
"7318"	"tripelennamine"	""	"Synthetic organic"	"yes"	""	""	""	"178103891"	"5587"	""	""	"CHEMBL1241"	""	""	""	""	"N-benzyl-N-[2-(dimethylamino)ethyl]pyridin-2-amine"	"tripelennamine"	"Pyribenzamine&reg;"	"CN(CCN(c1ccccn1)Cc1ccccc1)C"	"UFLGIAIHIAPJJC-UHFFFAOYSA-N"	"InChI=1S/C16H21N3/c1-18(2)12-13-19(16-10-6-7-11-17-16)14-15-8-4-3-5-9-15/h3-11H,12-14H2,1-2H3"	"yes"	""	""
"10002"	"triple modulator 10 [PMID: 29878767]"	""	"Synthetic organic"	""	""	""	""	"374883889"	"134611898"	""	""	""	""	""	""	""	"N-(benzenesulfonyl)-3-methoxy-4-({1-methyl-5-[(phenylcarbamoyl)amino]-1H-indol-3-yl}methyl)benzamide"	""	""	"COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)Nc1ccccc1)C)C(=O)NS(=O)(=O)c1ccccc1"	"CJILPLPDEJBFHA-UHFFFAOYSA-N"	"InChI=1S/C31H28N4O5S/c1-35-20-23(27-19-25(15-16-28(27)35)33-31(37)32-24-9-5-3-6-10-24)17-21-13-14-22(18-29(21)40-2)30(36)34-41(38,39)26-11-7-4-8-12-26/h3-16,18-20H,17H2,1-2H3,(H,34,36)(H2,32,33,37)"	"yes"	""	""
"10126"	"tryptanthrin 5i"	""	"Synthetic organic"	""	""	""	""	"381118836"	"478573"	""	""	"CHEMBL432537"	""	""	""	""	""	""	"compound 5i [PMID: 24099220]"	"[O-][N+](=O)c1ccc2c(c1)C(=O)c1n2c(=O)c2c(n1)cccc2"	"UFMQJYHLIUACCG-UHFFFAOYSA-N"	"InChI=1S/C15H7N3O4/c19-13-10-7-8(18(21)22)5-6-12(10)17-14(13)16-11-4-2-1-3-9(11)15(17)20/h1-7H"	"yes"	""	""
"9702"	"tubastatin A"	""	"Synthetic organic"	""	""	""	""	"348353661"	"49850262"	""	""	"CHEMBL2018302"	""	""	""	""	"N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide"	""	""	"ONC(=O)c1ccc(cc1)Cn1c2ccccc2c2c1CCN(C2)C"	"GOVYBPLHWIEHEJ-UHFFFAOYSA-N"	"InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)"	"yes"	""	""
"10107"	"TUG-1375"	""	"Synthetic organic"	""	""	""	""	"381118817"	"137321147"	""	""	""	""	""	""	""	"(2R,4R)-2-(2-chlorophenyl)-3-(4-(3,5-dimethylisoxazol-4-yl)benzoyl)thiazolidine-4-carboxylic acid"	""	"compound 31 [PMID: 30247908]|TUG1375"	"O=C(N1[C@H](CS[C@H]1c1ccccc1Cl)C(=O)O)c1ccc(cc1)c1c(C)noc1C"	"RZAMDGBOOPJHJQ-NQIIRXRSSA-N"	"InChI=1S/C22H19ClN2O4S/c1-12-19(13(2)29-24-12)14-7-9-15(10-8-14)20(26)25-18(22(27)28)11-30-21(25)16-5-3-4-6-17(16)23/h3-10,18,21H,11H2,1-2H3,(H,27,28)/t18-,21+/m1/s1"	"yes"	""	""
"13892"	"TUG-2181"	""	"Synthetic organic"	""	""	""	""	"513757577"	"156499897"	""	""	""	""	""	""	""	""	""	"compound 40g [PMID: 40183744]|compound I-319 [WO2022167445A1]|TUG2181"	"CCOC1=CC=C(CCC2=NC(OCC3CCCCO3)=CC(O)=C2)C=C1"	"BKDQRSMIHIMMTG-UHFFFAOYSA-N"	"InChI=1S/C21H27NO4/c1-2-24-19-10-7-16(8-11-19)6-9-17-13-18(23)14-21(22-17)26-15-20-5-3-4-12-25-20/h7-8,10-11,13-14,20H,2-6,9,12,15H2,1H3,(H,22,23)"	"yes"	""	""
"5073"	"tumour necrosis factor membrane form"	"Human"	"Peptide"	""	""	""	""	"178101766"	""	"P01375"	"ENSG00000232810"	""	""	""	""	""	""	""	"cachectin|necrosin|TNF membrane form|TNF&alpha;"	""	""	""	"yes"	""	""
"5074"	"tumour necrosis factor shed form"	"Human"	"Peptide"	""	""	""	""	"178101767"	""	"P01375"	"ENSG00000232810"	""	""	""	""	""	""	""	"cachectin|necrosin|TNF alpha soluble form|TNF shed form|tumor necrosis factor soluble form"	""	""	""	"yes"	""	""
"9779"	"TY-51469"	""	"Synthetic organic"	""	""	""	""	"354702252"	"9828275"	""	""	""	""	""	""	""	"2-[4-[(5-fluoro-3-methyl-1-benzothiophen-2-yl)sulfonylamino]-3-methylsulfonylphenyl]-1,3-thiazole-4-carboxylic acid"	""	""	"Fc1ccc2c(c1)c(C)c(s2)S(=O)(=O)Nc1ccc(cc1S(=O)(=O)C)c1scc(n1)C(=O)O"	"CBRCULCCRGSSLB-UHFFFAOYSA-N"	"InChI=1S/C20H15FN2O6S4/c1-10-13-8-12(21)4-6-16(13)31-20(10)33(28,29)23-14-5-3-11(7-17(14)32(2,26)27)18-22-15(9-30-18)19(24)25/h3-9,23H,1-2H3,(H,24,25)"	"yes"	""	""
"13823"	"TYD-68"	""	"Synthetic organic"	""	""	""	""	"507750456"	"172879841"	""	""	""	""	""	""	""	"6-((5-((4-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)cyclohexyl)carbamoyl)pyridin-2-yl)amino)-4-((3-(5-fluoropyrimidin-2-yl)-2-methoxyphenyl)amino)-N-methylnicotinamide"	""	"TYK2 PROTAC 15t [PMID: 40116635]"	"COC1=C(NC2=CC(NC3=CC=C(C(NC4CCC(NC5=CC6=C(C(N(C7C(NC(CC7)=O)=O)C6=O)=O)C=C5)CC4)=O)C=N3)=NC=C2C(NC)=O)C=CC=C1C8=NC=C(F)C=N8"	"NKSVQPQJZWJRLO-UHFFFAOYSA-N"	"InChI=1S/C43H40FN11O7/c1-45-40(58)30-21-47-35(17-32(30)52-31-5-3-4-28(37(31)62-2)38-48-19-23(44)20-49-38)53-34-14-6-22(18-46-34)39(57)51-25-9-7-24(8-10-25)50-26-11-12-27-29(16-26)43(61)55(42(27)60)33-13-15-36(56)54-41(33)59/h3-6,11-12,14,16-21,24-25,33,50H,7-10,13,15H2,1-2H3,(H,45,58)(H,51,57)(H,54,56,59)(H2,46,47,52,53)"	"yes"	""	""
"11425"	"TYK2 inhibitor 14l"	""	"Synthetic organic"	""	""	""	""	"440816794"	"155817516"	""	""	""	""	""	""	""	"3-(4-(5-Fluoro-2-((1-((trifluoromethyl)sulfonyl)-1H-indol-5-yl)amino)pyrimidin-4-yl)-1H-pyrazol-1-yl)propanenitrile"	""	""	"N#CCCn1ncc(c1)c1nc(ncc1F)Nc1ccc2c(c1)ccn2S(=O)(=O)C(F)(F)F"	"CGDRNYQWTORWBT-UHFFFAOYSA-N"	"InChI=1S/C19H13F4N7O2S/c20-15-10-25-18(28-17(15)13-9-26-29(11-13)6-1-5-24)27-14-2-3-16-12(8-14)4-7-30(16)33(31,32)19(21,22)23/h2-4,7-11H,1,6H2,(H,25,27,28)"	"yes"	""	""
"1888"	"U46619"	""	"Synthetic organic"	""	""	""	""	"135651289"	"5311493"	""	""	"CHEMBL521784"	""	""	""	""	"(Z)-7-[(1S,4R,5R,6S)-5-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid"	""	"11&alpha;,9&alpha;-epoxymethano-PGH2|U 46619|U-46619"	"CCCCC[C@@H](/C=C/[C@H]1[C@@H]2OC[C@H]([C@@H]1C/C=C\CCCC(=O)O)C2)O"	"LQANGKSBLPMBTJ-BRSNVKEHSA-N"	"InChI=1S/C21H34O4/c1-2-3-6-9-17(22)12-13-19-18(16-14-20(19)25-15-16)10-7-4-5-8-11-21(23)24/h4,7,12-13,16-20,22H,2-3,5-6,8-11,14-15H2,1H3,(H,23,24)/b7-4-,13-12+/t16-,17+,18+,19-,20-/m1/s1"	"yes"	""	""
"8920"	"ublituximab"	""	"Antibody"	"yes"	""	""	""	"310264701"	""	""	""	""	""	""	""	""	""	"ublituximab"	"Briumvi&reg;|LFB-R603|TG-1101|TGTX-1101|ublituximab-xiiy"	""	""	""	"yes"	""	""
"13912"	"UCB-9260"	""	"Synthetic organic"	""	""	""	""	"513757597"	"72700327"	""	""	"CHEMBL4743779"	""	""	""	""	"[1-[(2,5-dimethylphenyl)methyl]-6-(1-methylpyrazol-4-yl)benzimidazol-2-yl]-pyridin-4-ylmethanol"	""	"UCB9260"	"CN1C=C(C=N1)C2=CC3=C(C=C2)N=C(C(O)C4=CC=NC=C4)N3CC5=CC(C)=CC=C5C"	"RZGFWGNCSYUEPR-UHFFFAOYSA-N"	"InChI=1S/C26H25N5O/c1-17-4-5-18(2)21(12-17)16-31-24-13-20(22-14-28-30(3)15-22)6-7-23(24)29-26(31)25(32)19-8-10-27-11-9-19/h4-15,25,32H,16H2,1-3H3"	"yes"	""	""
"10359"	"ulinastatin"	"Human"	"Peptide"	"yes"	""	""	""	"387271625"	""	"P02760"	"ENSG00000106927"	""	""	""	""	""	""	"ulinastatin"	"Miraclid&reg;|Ulinase&reg;|Urinastatin&reg;"	""	""	""	"yes"	""	""
"9161"	"ulocuplumab"	""	"Antibody"	""	""	""	""	"315661244"	""	""	""	""	""	""	""	""	""	"ulocuplumab"	"BMS-936564|MDX-1338"	""	""	""	"yes"	""	""
"8916"	"umbralisib"	""	"Synthetic organic"	"yes"	""	""	""	"310264697"	"72950888"	""	""	"CHEMBL3948730"	""	""	""	""	"2-[(1S)-1-[4-amino-3-(3-fluoro-4-propan-2-yloxyphenyl)pyrazolo[3,4-d]pyrimidin-1-yl]ethyl]-6-fluoro-3-(3-fluorophenyl)chromen-4-one"	"umbralisib"	"example A1 [US2014011819]|RP-5264|RP5264|TGR-1202|TGR1202|Ukoniq&reg;"	"CC(Oc1ccc(cc1F)c1nn(c2c1c(N)ncn2)[C@H](c1oc2ccc(cc2c(=O)c1c1cccc(c1)F)F)C)C"	"IUVCFHHAEHNCFT-INIZCTEOSA-N"	"InChI=1S/C31H24F3N5O3/c1-15(2)41-24-9-7-18(12-22(24)34)27-26-30(35)36-14-37-31(26)39(38-27)16(3)29-25(17-5-4-6-19(32)11-17)28(40)21-13-20(33)8-10-23(21)42-29/h4-16H,1-3H3,(H2,35,36,37)/t16-/m0/s1"	"yes"	""	""
"7354"	"umeclidinium"	""	"Synthetic organic"	"yes"	""	""	""	"178103926"	"11519070"	""	""	"CHEMBL1187833"	""	""	""	""	"di(phenyl)-[1-[2-(phenylmethoxy)ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]methanol"	"umeclidinium bromide"	"GSK573719A|Incruse Ellipta&reg;"	"OC(C12CC[N+](CC1)(CC2)CCOCc1ccccc1)(c1ccccc1)c1ccccc1"	"FVTWTVQXNAJTQP-UHFFFAOYSA-N"	"InChI=1S/C29H34NO2/c31-29(26-12-6-2-7-13-26,27-14-8-3-9-15-27)28-16-19-30(20-17-28,21-18-28)22-23-32-24-25-10-4-1-5-11-25/h1-15,31H,16-24H2/q+1"	"yes"	""	""
"10131"	"UNC4203"	""	"Synthetic organic"	""	""	""	""	"381118841"	"118443595"	""	""	""	""	""	""	""	"trans-4-(5-(4-((4-Methyl-1,4-diazepan-1-yl)methyl)phenyl)-2-(((S)-pentan-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexan-1-ol"	""	"MERTK inhibitor 19 [PMID: 30347155]|UNC4203A [US20150291606A1]"	"CCC[C@@H](Nc1ncc2c(n1)n(cc2c1ccc(cc1)CN1CCCN(CC1)C)[C@@H]1CC[C@H](CC1)O)C"	"HYUGTGGDEAGXJP-HRNNMHKYSA-N"	"InChI=1S/C30H44N6O/c1-4-6-22(2)32-30-31-19-27-28(21-36(29(27)33-30)25-11-13-26(37)14-12-25)24-9-7-23(8-10-24)20-35-16-5-15-34(3)17-18-35/h7-10,19,21-22,25-26,37H,4-6,11-18,20H2,1-3H3,(H,31,32,33)/t22-,25-,26-/m0/s1"	"yes"	""	""
"9246"	"upadacitinib"	""	"Synthetic organic"	"yes"	""	""	""	"315661321"	"58557659"	""	""	""	""	""	""	""	""	"upadacitinib"	"ABT-494|Rinvoq&reg;"	"CC[C@@H]1CN(C[C@@H]1c1cnc2n1c1cc[nH]c1nc2)C(=O)NCC(F)(F)F"	"WYQFJHHDOKWSHR-MNOVXSKESA-N"	"InChI=1S/C17H19F3N6O/c1-2-10-7-25(16(27)24-9-17(18,19)20)8-11(10)13-5-22-14-6-23-15-12(26(13)14)3-4-21-15/h3-6,10-11,21H,2,7-9H2,1H3,(H,24,27)/t10-,11+/m1/s1"	"yes"	""	""
"9901"	"uracil 20"	""	"Synthetic organic"	""	""	""	""	"363894195"	"133081971"	""	""	""	""	""	""	""	"N-(3-(1-(((3S)-2-Hydroxy-5-oxotetrahydrofuran-3-yl)carbamoyl)cyclopropyl)-1- isopropyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-methyl-4-(naphthalen-2- ylamino)benzamide"	""	""	"O=C1OC([C@H](C1)NC(=O)C1(CC1)n1c(=O)c(NC(=O)c2ccc(cc2C)Nc2ccc3c(c2)cccc3)cn(c1=O)C(C)C)O"	"BTGMTHBOODBMHN-SUHMBNCMSA-N"	"InChI=1S/C33H33N5O7/c1-18(2)37-17-26(29(41)38(32(37)44)33(12-13-33)31(43)36-25-16-27(39)45-30(25)42)35-28(40)24-11-10-22(14-19(24)3)34-23-9-8-20-6-4-5-7-21(20)15-23/h4-11,14-15,17-18,25,30,34,42H,12-13,16H2,1-3H3,(H,35,40)(H,36,43)/t25-,30?/m0/s1"	"yes"	""	""
"9311"	"urelumab"	""	"Antibody"	""	""	""	""	"318164830"	""	""	""	""	""	""	""	""	""	"urelumab"	"BMS 663513|BMS-663513"	""	""	""	"yes"	""	""
"12883"	"usnoflast"	""	"Synthetic organic"	""	""	""	""	"485206004"	"154648184"	""	""	""	""	""	""	""	"1-[(E)-2-[(2R)-1,2-dimethylpyrrolidin-2-yl]ethenyl]sulfonyl-3-(1,2,3,5,6,7-hexahydro-s-indacen-4-yl)urea"	""	"Example-6  [WO2020148619A1]|ZY-IL1|ZYIL-1|ZYIL1"	"C[C@@]1(CCCN1C)/C=C/S(=O)(=O)NC(=O)NC2=C3CCCC3=CC4=C2CCC4"	"HAMGPBKPACGWND-ZOXUKVPXSA-N"	"InChI=1S/C21H29N3O3S/c1-21(10-5-12-24(21)2)11-13-28(26,27)23-20(25)22-19-17-8-3-6-15(17)14-16-7-4-9-18(16)19/h11,13-14H,3-10,12H2,1-2H3,(H2,22,23,25)/b13-11+/t21-/m1/s1"	"yes"	""	""
"6885"	"ustekinumab"	""	"Antibody"	"yes"	""	""	""	"178103467"	""	""	""	""	""	""	""	""	""	"ustekinumab"	"CNTO-1275|L04AC05|Stelara&reg;|TT-20"	""	""	""	"yes"	""	""
"9244"	"utomilumab"	""	"Antibody"	""	""	""	""	"315661319"	""	""	""	""	""	""	""	""	""	"utomilumab"	"PF-05082566"	""	""	""	"yes"	""	""
"8107"	"vactosertib"	""	"Synthetic organic"	""	""	""	""	"249565787"	"54766013"	""	""	"CHEMBL3260567"	""	""	""	""	"2-fluoro-N-[[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]methyl]aniline"	"vactosertib"	"EW-7197|EW7197|NOV-1301|TEW-7197"	"Cc1cccc(n1)c1[nH]c(nc1c1ccc2n(c1)ncn2)CNc1ccccc1F"	"FJCDSQATIJKQKA-UHFFFAOYSA-N"	"InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29)"	"yes"	""	""
"9434"	"vadastuximab talirine"	""	"Antibody"	""	""	""	""	"329968375"	""	""	""	""	""	""	""	""	""	"vadastuximab talirine"	"SGN-CD33A"	""	""	""	"yes"	""	""
"11487"	"valategrast"	""	"Synthetic organic"	""	""	""	""	"440816855"	"11563636"	""	""	"CHEMBL2107792"	""	""	""	""	""	"valategrast"	"R-411|RO-0272441"	"CCN(CCOC(=O)[C@@H](NC(=O)c1c(C)cccc1Cl)Cc1ccc(cc1)NC(=O)c1c(Cl)cccc1Cl)CC"	"VZVNFRFMDNFPOM-VWLOTQADSA-N"	"InChI=1S/C30H32Cl3N3O4/c1-4-36(5-2)16-17-40-30(39)25(35-28(37)26-19(3)8-6-9-22(26)31)18-20-12-14-21(15-13-20)34-29(38)27-23(32)10-7-11-24(27)33/h6-15,25H,4-5,16-18H2,1-3H3,(H,34,38)(H,35,37)/t25-/m0/s1"	"yes"	""	""
"2894"	"valdecoxib"	""	"Synthetic organic"	"yes"	"yes"	""	""	"178100243"	"119607"	""	""	"CHEMBL865"	""	""	""	""	"4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonamide"	"valdecoxib"	"Bextra&reg;|SC-65872"	"Cc1onc(c1c1ccc(cc1)S(=O)(=O)N)c1ccccc1"	"LNPDTQAFDNKSHK-UHFFFAOYSA-N"	"InChI=1S/C16H14N2O3S/c1-11-15(12-7-9-14(10-8-12)22(17,19)20)16(18-21-11)13-5-3-2-4-6-13/h2-10H,1H3,(H2,17,19,20)"	"yes"	""	""
"9247"	"vamorolone"	""	"Synthetic organic"	"yes"	""	""	""	"315661322"	"3035000"	""	""	"CHEMBL2348780"	""	""	""	""	"(8S,10S,13S,14S,16R,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-one"	"vamorolone"	"Agamree&reg;|VBP-15|VBP15"	"OCC(=O)[C@@]1(O)[C@H](C)C[C@@H]2[C@]1(C)CC=C1[C@H]2CCC2=CC(=O)C=C[C@]12C"	"ZYTXTXAMMDTYDQ-DGEXFFLYSA-N"	"InChI=1S/C22H28O4/c1-13-10-18-16-5-4-14-11-15(24)6-8-20(14,2)17(16)7-9-21(18,3)22(13,26)19(25)12-23/h6-8,11,13,16,18,23,26H,4-5,9-10,12H2,1-3H3/t13-,16-,18+,20+,21+,22+/m1/s1"	"yes"	""	""
"11718"	"vanin-1 inhibitor [PMID: 33196323]"	""	"Synthetic organic"	""	""	""	""	"458923753"	"124112161"	""	""	""	""	""	""	""	"3-[2-[(1-pyrimidin-5-ylcyclopropyl)amino]pyrimidine-5-carbonyl]benzonitrile"	""	"example 1 [WO2016193844A1]"	"O=C(c1cc(ccc1)C#N)c1cnc(NC2(CC2)c2cncnc2)nc1"	"OJUWWGHSEBTYGS-UHFFFAOYSA-N"	"InChI=1S/C19H14N6O/c20-7-13-2-1-3-14(6-13)17(26)15-8-23-18(24-9-15)25-19(4-5-19)16-10-21-12-22-11-16/h1-3,6,8-12H,4-5H2,(H,23,24,25)"	"yes"	""	""
"9657"	"varespladib"	""	"Synthetic organic"	""	""	""	""	"348353616"	"155815"	""	""	"CHEMBL148674"	""	""	""	""	"2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid"	"varespladib"	"compound 6m [PMID: 8978844]|LY315920|S-5920|varespladib methyl (A-002)|varespladib sodium (A-001)"	"CCc1c(C(=O)C(=O)N)c2c(n1Cc1ccccc1)cccc2OCC(=O)O"	"BHLXTPHDSZUFHR-UHFFFAOYSA-N"	"InChI=1S/C21H20N2O5/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25)"	"yes"	""	""
"12187"	"varokibart"	""	"Antibody"	""	""	""	""	"472319309"	""	""	""	""	""	""	""	""	""	"varokibart"	""	""	""	""	"yes"	""	""
"10030"	"VCE-004.3"	""	"Synthetic organic"	""	""	""	""	"375973218"	"91972027"	""	""	""	""	""	""	""	"4-hydroxy-3-[(1R,6R)-3-methyl-6-prop-1-en-2-ylcyclohex-2-en-1-yl]-6-pentyl-5-(pentylamino)cyclohexa-3,5-diene-1,2-dione"	""	""	"CCCCCNC1=C(CCCCC)C(=O)C(=O)C(=C1O)[C@@H]1C=C(C)CC[C@H]1C(=C)C"	"CIEWIZBPWBLHSB-PZJWPPBQSA-N"	"InChI=1S/C26H39NO3/c1-6-8-10-12-20-23(27-15-11-9-7-2)25(29)22(26(30)24(20)28)21-16-18(5)13-14-19(21)17(3)4/h16,19,21,27,29H,3,6-15H2,1-2,4-5H3/t19-,21+/m0/s1"	"yes"	""	""
"10231"	"vecabrutinib"	""	"Synthetic organic"	""	""	""	""	"381744913"	"72547837"	""	""	""	""	""	""	""	"(3R,3'R,4'S)-1'-(6-amino-5-fluoropyrimidin-4-yl)-3-[3-chloro-5-(trifluoromethyl)anilino]-2-oxo[1,3'-bipiperidine]-4'-carboxamide"	"vecabrutinib"	"BIIB-062|BIIB062|SNS-062|SNS062"	"Clc1cc(N[C@@H]2CCCN(C2=O)[C@H]2CN(CC[C@@H]2C(=O)N)c2ncnc(c2F)N)cc(c1)C(F)(F)F"	"QLRRJMOBVVGXEJ-XHSDSOJGSA-N"	"InChI=1S/C22H24ClF4N7O2/c23-12-6-11(22(25,26)27)7-13(8-12)32-15-2-1-4-34(21(15)36)16-9-33(5-3-14(16)19(29)35)20-17(24)18(28)30-10-31-20/h6-8,10,14-16,32H,1-5,9H2,(H2,29,35)(H2,28,30,31)/t14-,15+,16-/m0/s1"	"yes"	""	""
"7437"	"vedolizumab"	""	"Antibody"	"yes"	""	""	""	"178104009"	""	""	""	""	""	""	""	""	""	"vedolizumab"	"Entyvio&reg;|LDP-02|LDP02|MLN-0002|MLN-002|MLN002"	""	""	""	"yes"	""	""
"9325"	"velsecorat"	""	"Synthetic organic"	""	""	""	""	"318164844"	"67041274"	""	""	"CHEMBL3666807"	""	""	""	""	"3-{5-[(1R,2S)-2-(2,2-difluoropropanamido)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)propoxy]-1H-indazol-1-yl}-N-[(3R)-oxolan-3-yl]benzamide"	"velsecorat"	"AZ13189620|AZD7594|compound 15m [PMID: 28937774]"	"C[C@@H]([C@@H](c1ccc2c(c1)OCCO2)Oc1ccc2c(c1)cnn2c1cccc(c1)C(=O)N[C@H]1COCC1)NC(=O)C(F)(F)C"	"ZZWJKLGCDHYVMB-BWGXUDETSA-N"	"InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27)44-25-7-8-26-22(15-25)17-35-38(26)24-5-3-4-21(14-24)30(39)37-23-10-11-41-18-23/h3-9,14-17,19,23,29H,10-13,18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23+,29-/m0/s1"	"yes"	""	""
"8268"	"veltuzumab"	""	"Antibody"	""	""	""	""	"252166480"	""	""	""	""	""	""	""	""	""	"veltuzumab"	"hA20|IMMU-106"	""	""	""	"yes"	""	""
"5893"	"vemurafenib"	""	"Synthetic organic"	"yes"	""	""	""	"178102516"	"42611257"	""	""	"CHEMBL1229517"	""	""	""	""	"N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide"	"vemurafenib"	"PLX4032|RG7204|Zelboraf&reg;"	"CCCS(=O)(=O)Nc1ccc(c(c1F)C(=O)c1c[nH]c2c1cc(cn2)c1ccc(cc1)Cl)F"	"GPXBXXGIAQBQNI-UHFFFAOYSA-N"	"InChI=1S/C23H18ClF2N3O3S/c1-2-9-33(31,32)29-19-8-7-18(25)20(21(19)26)22(30)17-12-28-23-16(17)10-14(11-27-23)13-3-5-15(24)6-4-13/h3-8,10-12,29H,2,9H2,1H3,(H,27,28)"	"yes"	""	""
"8318"	"venetoclax"	""	"Synthetic organic"	"yes"	""	""	""	"252166530"	"49846579"	""	""	"CHEMBL3137309"	""	""	""	""	"4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[3-nitro-4-(oxan-4-ylmethylamino)phenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide"	"venetoclax"	"ABT-199|GDC-0199|Venclexta&reg;|Venclyxto&reg;"	"Clc1ccc(cc1)C1=C(CCC(C1)(C)C)CN1CCN(CC1)c1ccc(c(c1)Oc1cnc2c(c1)cc[nH]2)C(=O)NS(=O)(=O)c1ccc(c(c1)[N+](=O)[O-])NCC1CCOCC1"	"LQBVNQSMGBZMKD-UHFFFAOYSA-N"	"InChI=1S/C45H50ClN7O7S/c1-45(2)15-11-33(39(26-45)31-3-5-34(46)6-4-31)29-51-17-19-52(20-18-51)35-7-9-38(42(24-35)60-36-23-32-12-16-47-43(32)49-28-36)44(54)50-61(57,58)37-8-10-40(41(25-37)53(55)56)48-27-30-13-21-59-22-14-30/h3-10,12,16,23-25,28,30,48H,11,13-15,17-22,26-27,29H2,1-2H3,(H,47,49)(H,50,54)"	"yes"	""	""
"9046"	"vercirnon"	""	"Synthetic organic"	""	""	""	""	"315661131"	"10343454"	""	""	"CHEMBL2178578"	""	""	""	""	"4-tert-butyl-N-[4-chloro-2-(1-oxidopyridin-1-ium-4-carbonyl)phenyl]benzenesulfonamide"	"vercirnon"	"CCX282-B|GSK'786|GSK1605786|GSK1605786A|Traficet-EN"	"Clc1ccc(c(c1)C(=O)c1cc[n+](cc1)[O-])NS(=O)(=O)c1ccc(cc1)C(C)(C)C"	"JRWROCIMSDXGOZ-UHFFFAOYSA-N"	"InChI=1S/C22H21ClN2O4S/c1-22(2,3)16-4-7-18(8-5-16)30(28,29)24-20-9-6-17(23)14-19(20)21(26)15-10-12-25(27)13-11-15/h4-14,24H,1-3H3"	"yes"	""	""
"10052"	"verdiperstat"	""	"Synthetic organic"	""	""	""	""	"375973240"	"11528958"	""	""	""	""	""	""	""	"1-(2-propan-2-yloxyethyl)-2-sulfanylidene-5H-pyrrolo[2,3-e]pyrimidin-4-one"	"verdiperstat"	"AZD-3241|AZD3241"	"CC(OCCn1c(=S)[nH]c(=O)c2c1cc[nH]2)C"	"FVJCUZCRPIMVLB-UHFFFAOYSA-N"	"InChI=1S/C11H15N3O2S/c1-7(2)16-6-5-14-8-3-4-12-9(8)10(15)13-11(14)17/h3-4,7,12H,5-6H2,1-2H3,(H,13,15,17)"	"yes"	""	""
"6193"	"verlukast"	""	"Synthetic organic"	""	""	""	""	"178102814"	"6509849"	""	""	"CHEMBL280481"	""	""	""	""	"3-[(R)-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-(3-dimethylamino-3-oxopropyl)sulfanylmethyl]sulfanylpropanoic acid"	"verlukast"	"MK-679|MK679"	"OC(=O)CCS[C@H](c1cccc(c1)/C=C/c1ccc2c(n1)cc(cc2)Cl)SCCC(=O)N(C)C"	"AXUZQJFHDNNPFG-LHAVAQOQSA-N"	"InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+/t26-/m1/s1"	"yes"	""	""
"14367"	"vexicitinib"	""	"Synthetic organic"	""	""	""	""	"523352159"	"177924590"	""	""	""	""	""	""	""	"4-(Cyclopropylamino)-2-[[(4aR)-3-(cyclopropylsulfonyl)-1,2,3,4,4a,5-hexahydropyrazino[2,1-c][1,4]benzoxazin-8-yl]amino]-5-pyrimidinecarboxamide"	"vexicitinib"	"compound I [WO2022188796]"	"[H][C@@]12COC3=C(C=CC(NC4=NC=C(C(N)=O)C(NC5CC5)=N4)=C3)N1CCN(CS(=O)(=O)C6CC6)C2"	"UUNAWUCGRQGIAD-MRXNPFEDSA-N"	"InChI=1S/C23H29N7O4S/c24-21(31)18-10-25-23(28-22(18)26-14-1-2-14)27-15-3-6-19-20(9-15)34-12-16-11-29(7-8-30(16)19)13-35(32,33)17-4-5-17/h3,6,9-10,14,16-17H,1-2,4-5,7-8,11-13H2,(H2,24,31)(H2,25,26,27,28)/t16-/m1/s1"	"yes"	""	""
"14383"	"VI-8"	""	"Synthetic organic"	""	""	""	""	"523352175"	"177924592"	""	""	""	""	""	""	""	"(E)-N′-Hydroxy-4-((6-((5-Hydroxy-4-Oxo-8-((E)-3-Oxo-3-(4-(Trifluoromethyl)phenyl)prop-1-en-1-yl)-2-Phenyl-4H-Chromen-7-yl)oxy)hexyl)oxy)benzimidamide"	""	""	"O/N=C(\C1=CC=C(C=C1)OCCCCCCOC2=CC(=C3C(C=C(OC3=C2/C=C/C(C4=CC=C(C=C4)C(F)(F)F)=O)C5=CC=CC=C5)=O)O)/N"	"HJKMPCAUYPXBQX-VHEBQXMUSA-N"	"InChI=1S/C38H33F3N2O7/c39-38(40,41)27-14-10-24(11-15-27)30(44)19-18-29-34(23-32(46)35-31(45)22-33(50-36(29)35)25-8-4-3-5-9-25)49-21-7-2-1-6-20-48-28-16-12-26(13-17-28)37(42)43-47/h3-5,8-19,22-23,46-47H,1-2,6-7,20-21H2,(H2,42,43)/b19-18+"	"yes"	""	""
"9860"	"vidofludimus"	""	"Synthetic organic"	""	""	""	""	"363894154"	"9820008"	""	""	"CHEMBL197194"	""	""	""	""	"2-[[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl]cyclopentene-1-carboxylic acid"	"vidofludimus"	"4SC-101|IMU-838 (vidofludimus calcium)|SC12267"	"COc1cccc(c1)c1ccc(c(c1)F)NC(=O)C1=C(CCC1)C(=O)O"	"XPRDUGXOWVXZLL-UHFFFAOYSA-N"	"InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2,4-5,8-11H,3,6-7H2,1H3,(H,22,23)(H,24,25)"	"yes"	""	""
"10169"	"vidupiprant"	""	"Synthetic organic"	""	""	""	""	"381118879"	"42641863"	""	""	"CHEMBL1951575"	""	""	""	""	"2-[4-[4-(tert-butylcarbamoyl)-2-[(2-chloro-4-cyclopropylphenyl)sulfonylamino]phenoxy]-5-chloro-2-fluorophenyl]acetic acid"	"vidupiprant"	"AMG 853|AMG-853|AMG853|compound 2 [PMID: 24900313]"	"OC(=O)Cc1cc(Cl)c(cc1F)Oc1ccc(cc1NS(=O)(=O)c1ccc(cc1Cl)C1CC1)C(=O)NC(C)(C)C"	"PFWVGKROPKKEDW-UHFFFAOYSA-N"	"InChI=1S/C28H27Cl2FN2O6S/c1-28(2,3)32-27(36)17-6-8-23(39-24-14-21(31)18(11-19(24)29)13-26(34)35)22(12-17)33-40(37,38)25-9-7-16(10-20(25)30)15-4-5-15/h6-12,14-15,33H,4-5,13H2,1-3H3,(H,32,36)(H,34,35)"	"yes"	""	""
"7353"	"vilanterol"	""	"Synthetic organic"	"yes"	""	""	""	"178103925"	"10184665"	""	""	"CHEMBL1198857"	""	""	""	""	"4-[(1R)-2-[(6-{2-[(2,6-dichlorophenyl)methoxy]ethoxy}hexyl)amino]-1-hydroxyethyl]-2-(hydroxymethyl)phenol"	"vilanterol"	"GW642444X"	"OCc1cc(ccc1O)[C@H](CNCCCCCCOCCOCc1c(Cl)cccc1Cl)O"	"DAFYYTQWSAWIGS-DEOSSOPVSA-N"	"InChI=1S/C24H33Cl2NO5/c25-21-6-5-7-22(26)20(21)17-32-13-12-31-11-4-2-1-3-10-27-15-24(30)18-8-9-23(29)19(14-18)16-28/h5-9,14,24,27-30H,1-4,10-13,15-17H2/t24-/m0/s1"	"yes"	""	""
"12100"	"vimnerixin"	""	"Synthetic organic"	""	""	""	""	"472319222"	"71209600"	""	""	""	""	""	""	""	"N-[6-[(2R,3S)-3,4-dihydroxybutan-2-yl]oxy-2-[(4-fluorophenyl)methylsulfanyl]pyrimidin-4-yl]-3-methylazetidine-1-sulfonamide"	"vimnerixin"	"AZD-4721|AZD4721|compound 4 [WO2019055509A1]|RIST4721"	"CC1CN(C1)S(=O)(=O)Nc1cc(nc(n1)SCc1ccc(cc1)F)O[C@H](C)[C@H](CO)O"	"UCCNQCNIPRKLRP-CJNGLKHVSA-N"	"InChI=1S/C19H25FN4O5S2/c1-12-8-24(9-12)31(27,28)23-17-7-18(29-13(2)16(26)10-25)22-19(21-17)30-11-14-3-5-15(20)6-4-14/h3-7,12-13,16,25-26H,8-11H2,1-2H3,(H,21,22,23)/t13-,16+/m1/s1"	"yes"	""	""
"1152"	"VIP"	"Human, Mouse, Rat"	"Peptide"	""	""	""	""	"135651911"	"16129679"	"P01282|P32648|P01283"	"ENSG00000146469|ENSRNOG00000018808"	""	""	""	""	""	""	""	""	"NCCCCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)O)CC(=O)N)CC(C)C)C(CC)C)CO)CC(=O)N)CC(C)C)Cc1ccc(cc1)O)CCCCN)CCCCN)C(C)C)C)CCSC)CCC(=O)N)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(O)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(C(O)C)NC(=O)C(NC(=O)C(C(C)C)NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(Cc1nc[nH]c1)N)CO)CC(=O)O)C)Cc1ccccc1)CC(=O)O)CC(=O)N)Cc1ccc(cc1)O)CCCNC(=N)N)CC(C)C)CCCNC(=N)N"	"VBUWHHLIZKOSMS-UHFFFAOYSA-N"	"InChI=1S/C147H237N43O43S/c1-18-75(12)115(142(229)180-96(56-72(6)7)131(218)183-104(145(232)233)63-110(155)200)188-139(226)106(68-192)185-134(221)101(62-109(154)199)177-130(217)95(55-71(4)5)174-132(219)97(58-81-37-41-84(195)42-38-81)175-125(212)88(33-23-26-49-149)167-123(210)89(34-24-27-50-150)171-140(227)113(73(8)9)186-118(205)76(13)164-121(208)93(47-53-234-17)170-127(214)92(45-46-107(152)197)169-122(209)87(32-22-25-48-148)166-124(211)90(35-28-51-161-146(156)157)168-129(216)94(54-70(2)3)173-126(213)91(36-29-52-162-147(158)159)172-143(230)116(78(15)193)189-136(223)98(59-82-39-43-85(196)44-40-82)176-133(220)100(61-108(153)198)178-135(222)103(65-112(203)204)182-144(231)117(79(16)194)190-137(224)99(57-80-30-20-19-21-31-80)181-141(228)114(74(10)11)187-119(206)77(14)165-128(215)102(64-111(201)202)179-138(225)105(67-191)184-120(207)86(151)60-83-66-160-69-163-83/h19-21,30-31,37-44,66,69-79,86-106,113-117,191-196H,18,22-29,32-36,45-65,67-68,148-151H2,1-17H3,(H2,152,197)(H2,153,198)(H2,154,199)(H2,155,200)(H,160,163)(H,164,208)(H,165,215)(H,166,211)(H,167,210)(H,168,216)(H,169,209)(H,170,214)(H,171,227)(H,172,230)(H,173,213)(H,174,219)(H,175,212)(H,176,220)(H,177,217)(H,178,222)(H,179,225)(H,180,229)(H,181,228)(H,182,231)(H,183,218)(H,184,207)(H,185,221)(H,186,205)(H,187,206)(H,188,226)(H,189,223)(H,190,224)(H,201,202)(H,203,204)(H,232,233)(H4,156,157,161)(H4,158,159,162)"	"yes"	""	""
"5612"	"vipadenant"	""	"Synthetic organic"	""	""	""	""	"178102246"	"21874557"	""	""	"CHEMBL447664"	""	""	""	""	"3-[(4-amino-3-methylphenyl)methyl]-7-furan-2-yltriazolo[5,4-d]pyrimidin-5-amine"	"vipadenant"	"BIIB 014|BIIB014|V2006"	"Nc1nc(c2ccco2)c2c(n1)n(nn2)Cc1ccc(c(c1)C)N"	"HQSBCDPYXDGTCL-UHFFFAOYSA-N"	"InChI=1S/C16H15N7O/c1-9-7-10(4-5-11(9)17)8-23-15-14(21-22-23)13(19-16(18)20-15)12-3-2-6-24-12/h2-7H,8,17H2,1H3,(H2,18,19,20)"	"yes"	""	""
"12209"	"vipoglanstat"	""	"Synthetic organic"	""	""	""	""	"472319329"	"56649447"	""	""	"CHEMBL3694493"	""	""	""	""	""	"vipoglanstat"	"BI 1029539|BI-1029539|BI1029539|GS-248|GS248"	"CC(C)(C)C(=O)NCc1c(c(c(cc1)Cl)Nc1nc2c(n1C)cc(c(c2)C(=O)NC1CCC(CC1)C(F)(F)F)OCC(F)F)Cl"	"PFORUFFGGNOLPJ-UHFFFAOYSA-N"	"InChI=1S/C30H34Cl2F5N5O3/c1-29(2,3)27(44)38-13-15-5-10-19(31)25(24(15)32)41-28-40-20-11-18(22(45-14-23(33)34)12-21(20)42(28)4)26(43)39-17-8-6-16(7-9-17)30(35,36)37/h5,10-12,16-17,23H,6-9,13-14H2,1-4H3,(H,38,44)(H,39,43)(H,40,41)"	"yes"	""	""
"13451"	"vixarelimab"	""	"Antibody"	""	""	""	""	"500839861"	""	""	""	""	""	""	""	""	""	"vixarelimab"	"KPL-716|KPL716"	""	""	""	"yes"	""	""
"10050"	"Vm24"	""	"Peptide"	""	""	""	""	"375973238"	""	""	""	""	""	""	""	""	""	""	"&alpha;-KTx 23.1"	""	""	""	"yes"	""	""
"8363"	"vobarilizumab"	""	"Antibody"	""	""	""	""	"252166575"	""	""	""	""	""	""	""	""	""	"vobarilizumab"	"ALX-0061"	""	""	""	"yes"	""	""
"11388"	"voclosporin"	""	"Peptide"	"yes"	""	""	""	"440816757"	"6918486"	""	""	""	""	""	""	""	"(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methylhepta-4,6-dienyl]-1,4,7,10,12,15,19,25,28-nonamethyl-6,9,18,24-tetrakis(2-methylpropyl)-3,21-di(propan-2-yl)-1,4,7,10,13,16,19,22,25,28,31-undecazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone"	"voclosporin"	"1,11-anhydro[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl- N-methyl-L-valyl-[(2S,3R,4R,6E)-3-hydroxy-4-methyl- 2-(methylamino)nona-6,8-dienoyl][(2S)-2-aminobutanoyl]- N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine]|E-ISA247|ISA(TX)247|ISA-247|ISA247|ISATX247|Lupkynis&reg;|R 1524|R-1524|R1524"	"C=C/C=C/C[C@H]([C@H]([C@H]1C(=O)N[C@@H](CC)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N([C@H](C(=O)N1C)C(C)C)C)CC(C)C)C)CC(C)C)C)C)C)O)C"	"BICRTLVBTLFLRD-PTWUADNWSA-N"	"InChI=1S/C63H111N11O12/c1-25-27-28-29-41(15)53(76)52-57(80)66-44(26-2)59(82)68(18)34-49(75)69(19)45(30-35(3)4)56(79)67-50(39(11)12)62(85)70(20)46(31-36(5)6)55(78)64-42(16)54(77)65-43(17)58(81)71(21)47(32-37(7)8)60(83)72(22)48(33-38(9)10)61(84)73(23)51(40(13)14)63(86)74(52)24/h25,27-28,35-48,50-53,76H,1,26,29-34H2,2-24H3,(H,64,78)(H,65,77)(H,66,80)(H,67,79)/b28-27+/t41-,42+,43-,44+,45+,46+,47+,48+,50+,51+,52+,53-/m1/s1"	"yes"	""	""
"7351"	"vortioxetine"	""	"Synthetic organic"	"yes"	""	""	""	"178103923"	"9966051"	""	""	"CHEMBL2104993"	""	""	""	""	"1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine"	"vortioxetine"	"Brintellix&reg;|compound 5m [PMID: 21486038]|Lu AA21004|Trintellix&reg;"	"Cc1ccc(c(c1)C)Sc1ccccc1N1CCNCC1"	"YQNWZWMKLDQSAC-UHFFFAOYSA-N"	"InChI=1S/C18H22N2S/c1-14-7-8-17(15(2)13-14)21-18-6-4-3-5-16(18)20-11-9-19-10-12-20/h3-8,13,19H,9-12H2,1-2H3"	"yes"	""	""
"9034"	"VRT-043198"	""	"Synthetic organic"	""	""	""	""	"315661119"	"11443029"	""	""	""	""	""	""	""	""	""	""	"O=C[C@@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](C(C)(C)C)NC(=O)c1ccc(c(c1)Cl)N)CC(=O)O"	"SOZONDBMOYWSRW-QANKJYHBSA-N"	"InChI=1S/C22H29ClN4O6/c1-22(2,3)18(26-19(31)12-6-7-15(24)14(23)9-12)21(33)27-8-4-5-16(27)20(32)25-13(11-28)10-17(29)30/h6-7,9,11,13,16,18H,4-5,8,10,24H2,1-3H3,(H,25,32)(H,26,31)(H,29,30)/t13-,16-,18+/m0/s1"	"yes"	""	""
"9296"	"vunakizumab"	""	"Antibody"	"yes"	""	""	""	"318164815"	""	""	""	""	""	""	""	""	""	""	"AnDajing (Chinese trade name)|SHR-1314"	""	""	""	"yes"	""	""
"6059"	"VX-702"	""	"Synthetic organic"	""	""	""	""	"178102680"	"10341154"	""	""	"CHEMBL1090090"	""	""	""	""	"2-(2,4-difluorophenyl)-6-[1-(2,6-difluorophenyl)carbamoylamino]pyridine-3-carboxamide"	""	"I14-1965|VX 702|VX702"	"Fc1ccc(c(c1)F)c1nc(ccc1C(=O)N)N(c1c(F)cccc1F)C(=O)N"	"FYSRKRZDBHOFAY-UHFFFAOYSA-N"	"InChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)"	"yes"	""	""
"8068"	"WH-4-023"	""	"Synthetic organic"	""	""	""	""	"249565748"	"11844351"	""	""	"CHEMBL213100"	""	""	""	""	"(2,6-dimethylphenyl) N-(2,4-dimethoxyphenyl)-N-[2-[[4-(4-methylpiperazin-1-yl)phenyl]amino]pyrimidin-4-yl]carbamate"	""	""	"COc1cc(OC)ccc1N(C(=O)Oc1c(C)cccc1C)c1ccnc(n1)Nc1ccc(cc1)N1CCN(CC1)C"	"NBTNHSGBRGTFJS-UHFFFAOYSA-N"	"InChI=1S/C32H36N6O4/c1-22-7-6-8-23(2)30(22)42-32(39)38(27-14-13-26(40-4)21-28(27)41-5)29-15-16-33-31(35-29)34-24-9-11-25(12-10-24)37-19-17-36(3)18-20-37/h6-16,21H,17-20H2,1-5H3,(H,33,34,35)"	"yes"	""	""
"14350"	"WJH-C19"	""	"Synthetic organic"	""	""	""	""	"523352142"	"177924589"	""	""	""	""	""	""	""	"(S)-N-(1-(4-Chlorophenyl)ethyl)-6-(2-(cyclopropanecarboxamido)benzo[d]thiazol-6-yl)imidazo[1,2-a]pyridine-3-carboxamide"	""	"compound 10e12 [PMID: 41628914]"	"O=C(NC=1SC2=C(N1)C=CC(=C2)C3=CN4C(C(N[C@@H](C)C5=CC=C(Cl)C=C5)=O)=CN=C4C=C3)C6CC6"	"ITLRRDLXVWEMIG-HNNXBMFYSA-N"	"InChI=1S/C27H22ClN5O2S/c1-15(16-4-8-20(28)9-5-16)30-26(35)22-13-29-24-11-7-19(14-33(22)24)18-6-10-21-23(12-18)36-27(31-21)32-25(34)17-2-3-17/h4-15,17H,2-3H2,1H3,(H,30,35)(H,31,32,34)/t15-/m0/s1"	"yes"	""	""
"10639"	"WJYK50"	""	"Synthetic organic"	""	""	""	""	"404859086"	"145954576"	""	""	""	""	""	""	""	"3-(Decyloxy)-N-hydroxy-4-methoxybenzamide"	""	"compound 1c [PMID: 29649738]"	"CCCCCCCCCCOc1cc(ccc1OC)C(=O)NO"	"QKPYTKNEFFAFOV-UHFFFAOYSA-N"	"InChI=1S/C18H29NO4/c1-3-4-5-6-7-8-9-10-13-23-17-14-15(18(20)19-21)11-12-16(17)22-2/h11-12,14,21H,3-10,13H2,1-2H3,(H,19,20)"	"yes"	""	""
"1048"	"WKYMVm"	""	"Peptide"	""	""	""	""	"135652638"	""	""	""	""	""	""	""	""	""	""	"Trp-Lys-Tyr-Met-Val-[D]Met|WKYMVM"	""	""	""	"yes"	""	""
"13463"	"WN1703"	""	"Synthetic organic"	""	""	""	""	"500839873"	"145973775"	""	""	"CHEMBL4217468"	""	""	""	""	"1-[3-cyano-4-[methyl(2-methylpropyl)amino]phenyl]pyrazole-4-carboxylic acid"	""	"compound 16c [PMID: 28918097]|WN-1703|XOR inhibitor 16c"	"CC(C)CN(C)C1=C(C=C(C=C1)N2C=C(C=N2)C(=O)O)C#N"	"HAJKHKHBTDJWQP-UHFFFAOYSA-N"	"InChI=1S/C16H18N4O2/c1-11(2)9-19(3)15-5-4-14(6-12(15)7-17)20-10-13(8-18-20)16(21)22/h4-6,8,10-11H,9H2,1-3H3,(H,21,22)"	"yes"	""	""
"1040"	"WRWWWW"	""	"Peptide"	""	""	""	""	"135652639"	""	""	""	""	""	""	""	""	""	""	"WRW4"	""	""	""	"yes"	""	""
"12621"	"WXFL10203614"	""	"Synthetic organic"	""	""	""	""	"479821411"	"134405105"	""	""	""	""	""	""	""	"(7R)-7-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carbonitrile"	""	"WX614|WXFL-10203614"	"CN([C@@H]1CCN2C=C(N=C2C1)C#N)C3=NC=NC4=C3C=CN4"	"TXNZCRVVBSQZCV-LLVKDONJSA-N"	"InChI=1S/C15H15N7/c1-21(15-12-2-4-17-14(12)18-9-19-15)11-3-5-22-8-10(7-16)20-13(22)6-11/h2,4,8-9,11H,3,5-6H2,1H3,(H,17,18,19)/t11-/m1/s1"	"yes"	""	""
"4447"	"XCL1"	"Mouse"	"Peptide"	""	""	""	""	"135651919"	""	"P47993"	"ENSMUSG00000026573"	""	""	""	""	""	""	""	"lymphotactin-&alpha;"	""	""	""	"yes"	""	""
"3647"	"XCL1"	"Human"	"Peptide"	""	""	""	""	"135651920"	""	"P47992"	"ENSG00000143184"	""	""	""	""	""	""	""	"c motif cytokine 1|cytokine SCM-1&alpha;|lymphotactin &alpha;"	""	""	""	"yes"	""	""
"4446"	"XCL1"	"Rat"	"Peptide"	""	""	""	""	"135651918"	""	"P51672"	"ENSRNOG00000002964"	""	""	""	""	""	""	""	"lymphotactin-&alpha;"	""	""	""	"yes"	""	""
"4370"	"XCL2"	"Human"	"Peptide"	""	""	""	""	"135651921"	""	"Q9UBD3"	"ENSG00000143185"	""	""	""	""	""	""	""	"C motif cytokine 2|lymphotactin &beta;"	""	""	""	"yes"	""	""
"13784"	"xeligekimab"	""	"Antibody"	"yes"	""	""	""	"507750417"	""	""	""	""	""	""	""	""	""	"xeligekimab"	"GR-1501|GR1501"	""	""	""	"yes"	""	""
"8528"	"Xilonix <small><sup>TN</sup></small>"	""	"Antibody"	""	""	""	""	"252166730"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"13448"	"YH35324"	""	"Peptide"	""	""	""	""	"500839858"	""	""	""	""	""	""	""	""	""	""	"IgE<sub>TRAP</sub>|YH-35324"	""	""	""	"yes"	""	""
"5090"	"YM90709"	""	"Synthetic organic"	""	""	""	""	"178101783"	"1103147"	""	""	"CHEMBL1356775"	""	""	""	""	"16,17-dimethoxy-21,21-dimethyl-1,3,10-triazapentacyclo[11.8.0.0^{2,11}.0^{4,9}.0^{14,19}]henicosa-2,4,6,8,10,12,14(19),15,17-nonaene"	""	"YM 90709|YM-90709"	"COc1cc2c(cc1OC)CC(n1c2cc2c1nc1c(n2)cccc1)(C)C"	"HIXSPVQXXDULHS-UHFFFAOYSA-N"	"InChI=1S/C22H21N3O2/c1-22(2)12-13-9-19(26-3)20(27-4)10-14(13)18-11-17-21(25(18)22)24-16-8-6-5-7-15(16)23-17/h5-11H,12H2,1-4H3"	"yes"	""	""
"11415"	"zabedosertib"	""	"Synthetic organic"	""	""	""	""	"440816784"	"121364961"	""	""	""	""	""	""	""	"N-[6-(2-hydroxypropan-2-yl)-2-(2-methylsulfonylethyl)indazol-5-yl]-6-(trifluoromethyl)pyridine-2-carboxamide"	"zabedosertib"	"BAY-1834845|BAY1834845"	"O=C(c1cccc(n1)C(F)(F)F)Nc1cc2cn(nc2cc1C(O)(C)C)CCS(=O)(=O)C"	"OQAMEEFUUFJZRS-UHFFFAOYSA-N"	"InChI=1S/C20H21F3N4O4S/c1-19(2,29)13-10-15-12(11-27(26-15)7-8-32(3,30)31)9-16(13)25-18(28)14-5-4-6-17(24-14)20(21,22)23/h4-6,9-11,29H,7-8H2,1-3H3,(H,25,28)"	"yes"	""	""
"13799"	"zadoprubart"	""	"Antibody"	""	""	""	""	"507750432"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"yes"	""	""
"3322"	"zafirlukast"	""	"Synthetic organic"	"yes"	""	""	""	"178100355"	"5717"	""	""	"CHEMBL603"	""	""	""	""	"cyclopentyl N-{3-[(2-methoxy-4-{[(2-methylbenzene)sulfonyl]carbamoyl}phenyl)methyl]-1-methyl-1H-indol-5-yl}carbamate"	"zafirlukast"	"Accolate&reg;|ICI-204219"	"COc1cc(ccc1Cc1cn(c2c1cc(cc2)NC(=O)OC1CCCC1)C)C(=O)NS(=O)(=O)c1ccccc1C"	"YEEZWCHGZNKEEK-UHFFFAOYSA-N"	"InChI=1S/C31H33N3O6S/c1-20-8-4-7-11-29(20)41(37,38)33-30(35)22-13-12-21(28(17-22)39-3)16-23-19-34(2)27-15-14-24(18-26(23)27)32-31(36)40-25-9-5-6-10-25/h4,7-8,11-15,17-19,25H,5-6,9-10,16H2,1-3H3,(H,32,36)(H,33,35)"	"yes"	""	""
"11406"	"zaloglanstat"	""	"Synthetic organic"	""	""	""	""	"440816775"	"136246033"	""	""	""	""	""	""	""	"N-[(4-chloro-3-{5-oxo-1-[4-(trifluoromethyl)phenyl]-2,5-dihydro-1H-1,2,4-triazol-3-yl}phenyl)methyl]-2,2-dimethylpropanamide"	"zaloglanstat"	""	"O=C(C(C)(C)C)NCc1ccc(c(c1)c1[nH]n(c(=O)n1)c1ccc(cc1)C(F)(F)F)Cl"	"DOVBVLUPCQSAGE-UHFFFAOYSA-N"	"InChI=1S/C21H20ClF3N4O2/c1-20(2,3)18(30)26-11-12-4-9-16(22)15(10-12)17-27-19(31)29(28-17)14-7-5-13(6-8-14)21(23,24)25/h4-10H,11H2,1-3H3,(H,26,30)(H,27,28,31)"	"yes"	""	""
"9861"	"zanubrutinib"	""	"Synthetic organic"	"yes"	""	""	""	"363894155"	"135565884"	""	""	"CHEMBL3936761"	""	""	""	""	"(7S)-2-(4-phenoxyphenyl)-7-(1-prop-2-enoylpiperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide"	"zanubrutinib"	"BGB-3111|BGB3111|Brukinsa&reg;|compound 27b [US9447106]"	"C=CC(=O)N1CCC(CC1)[C@@H]1CCNc2n1nc(c2C(=O)N)c1ccc(cc1)Oc1ccccc1"	"RNOAOAWBMHREKO-QFIPXVFZSA-N"	"InChI=1S/C27H29N5O3/c1-2-23(33)31-16-13-18(14-17-31)22-12-15-29-27-24(26(28)34)25(30-32(22)27)19-8-10-21(11-9-19)35-20-6-4-3-5-7-20/h2-11,18,22,29H,1,12-17H2,(H2,28,34)/t22-/m0/s1"	"yes"	""	""
"12155"	"zasocitinib"	""	"Synthetic organic"	""	""	""	""	"472319277"	"137441492"	""	""	""	""	""	""	""	"N-[(1R,2R)-2-methoxycyclobutyl]-7-(methylamino)-5-[(2-oxo-1-pyridin-2-ylpyridin-3-yl)amino]pyrazolo[1,5-a]pyrimidine-3-carboxamide"	"zasocitinib"	"compound I-908 [US20190256519A1]|NDI-034858|NDI034858|TAK-279|TAK279"	"CNc1cc(nc2c(cnn12)C(=O)N[C@@H]1CC[C@H]1OC)Nc1cccn(c1=O)c1ccccn1"	"BWINBHTTZLVXGT-NVXWUHKLSA-N"	"InChI=1S/C23H24N8O3/c1-24-20-12-18(27-16-6-5-11-30(23(16)33)19-7-3-4-10-25-19)29-21-14(13-26-31(20)21)22(32)28-15-8-9-17(15)34-2/h3-7,10-13,15,17,24H,8-9H2,1-2H3,(H,27,29)(H,28,32)/t15-,17-/m1/s1"	"yes"	""	""
"11488"	"zaurategrast"	""	"Synthetic organic"	""	""	""	""	"440816856"	"10186367"	""	""	"CHEMBL4303708"	""	""	""	""	"(2S)-2-[(2-bromo-3-oxospiro[3.5]non-1-en-1-yl)amino]-3-[4-(2,7-naphthyridin-1-ylamino)phenyl]propanoic acid"	"zaurategrast"	"CDP-323|CDP323"	"OC(=O)[C@@H](NC1=C(Br)C(=O)C21CCCCC2)Cc1ccc(cc1)Nc1nccc2c1cncc2"	"KYHVWHYLKOHLKA-FQEVSTJZSA-N"	"InChI=1S/C26H25BrN4O3/c27-21-22(26(23(21)32)10-2-1-3-11-26)31-20(25(33)34)14-16-4-6-18(7-5-16)30-24-19-15-28-12-8-17(19)9-13-29-24/h4-9,12-13,15,20,31H,1-3,10-11,14H2,(H,29,30)(H,33,34)/t20-/m0/s1"	"yes"	""	""
"14370"	"zecontimod"	""	"Synthetic organic"	""	""	""	""	"523352162"	"139433143"	""	""	""	""	""	""	""	"3-[[4-(4-fluorophenyl)-3-(pyrrolidin-1-ylmethyl)-2H-chromen-6-yl]oxy]propanoic acid"	"zecontimod"	"compound I-33 [US20220081429]"	"FC1=CC=C(C=C1)C2=C(COC3=C2C=C(C=C3)OCCC(=O)O)CN4CCCC4"	"XXARLKNSPVBUSQ-UHFFFAOYSA-N"	"InChI=1S/C23H24FNO4/c24-18-5-3-16(4-6-18)23-17(14-25-10-1-2-11-25)15-29-21-8-7-19(13-20(21)23)28-12-9-22(26)27/h3-8,13H,1-2,9-12,14-15H2,(H,26,27)"	"yes"	""	""
"10087"	"zegocractin"	""	"Synthetic organic"	""	""	""	""	"381118797"	"122507647"	""	""	"CHEMBL4753998"	""	""	""	""	"N-[5-(6-chloro-2,2-difluoro-1,3-benzodioxol-5-yl)pyrazin-2-yl]-2-fluoro-6-methylbenzamide"	"zegocractin"	"Auxora|CM-4620|CM4620|compound I [WO2016138472A1]"	"Clc1cc2OC(Oc2cc1c1ncc(nc1)NC(=O)c1c(C)cccc1F)(F)F"	"QQMKTHUGOQDEIL-UHFFFAOYSA-N"	"InChI=1S/C19H11ClF3N3O3/c1-9-3-2-4-12(21)17(9)18(27)26-16-8-24-13(7-25-16)10-5-14-15(6-11(10)20)29-19(22,23)28-14/h2-8H,1H3,(H,25,26,27)"	"yes"	""	""
"13490"	"zelebrudomide"	""	"Synthetic organic"	""	""	""	""	"500839900"	"146559796"	""	""	""	""	""	""	""	"3-[4-[1-[[(3S)-1-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-5-yl]pyrrolidin-3-yl]methyl]piperidin-4-yl]anilino]-5-piperidin-1-ylpyrazine-2-carboxamide"	"zelebrudomide"	"compound 28 [PMID: 38300987]|NX-2127|NX2127"	"NC(=O)C1=NC=C(N=C1NC2=CC=C(C=C2)C3CCN(C[C@@H]4CCN(C4)C5=CC6=C(C=C5)C(=O)N(C7CCC(=O)NC7=O)C6=O)CC3)N8CCCCC8"	"XLWJWCMQMBVNSG-ACXKHFGCSA-N"	"InChI=1S/C39H45N9O5/c40-35(50)34-36(43-32(21-41-34)46-15-2-1-3-16-46)42-27-6-4-25(5-7-27)26-13-17-45(18-14-26)22-24-12-19-47(23-24)28-8-9-29-30(20-28)39(53)48(38(29)52)31-10-11-33(49)44-37(31)51/h4-9,20-21,24,26,31H,1-3,10-19,22-23H2,(H2,40,50)(H,42,43)(H,44,49,51)/t24-,31?/m0/s1"	"yes"	""	""
"12893"	"zelnecirnon"	""	"Synthetic organic"	""	""	""	""	"485206014"	"139344142"	""	""	""	""	""	""	""	"3-[(3R)-3-[1-[5-chloro-4-[[(1R)-1-(2,4-dichlorophenyl)ethyl]amino]-6-methylpyrimidin-2-yl]azetidin-3-yl]piperidin-1-yl]-1-methylcyclobutane-1-carboxylic acid"	"zelnecirnon"	"example 37 [WO2019147862A1]|RPT-193|RPT193"	"CC1=C(C(=NC(=N1)N2CC(C2)[C@H]3CCCN(C3)C4CC(C4)(C)C(=O)O)N[C@H](C)C5=C(C=C(C=C5)Cl)Cl)Cl"	"ANPSFQZLPNWKHR-PRZTZBHNSA-N"	"InChI=1S/C27H34Cl3N5O2/c1-15(21-7-6-19(28)9-22(21)29)31-24-23(30)16(2)32-26(33-24)35-13-18(14-35)17-5-4-8-34(12-17)20-10-27(3,11-20)25(36)37/h6-7,9,15,17-18,20H,4-5,8,10-14H2,1-3H3,(H,36,37)(H,31,32,33)/t15-,17+,20?,27?/m1/s1"	"yes"	""	""
"13221"	"zemprocitinib"	""	"Synthetic organic"	""	""	""	""	"491300003"	"152231544"	""	""	""	""	""	""	""	""	"zemprocitinib"	"compound 1 [US20220009927]"	"N1(C=NC=2C1=C3C(=NC2)NC=C3)C45CC(C4)(C5)NS(=O)(=O)CCC"	"WBKCMWRKRQABQF-UHFFFAOYSA-N"	"InChI=1S/C16H19N5O2S/c1-2-5-24(22,23)20-15-7-16(8-15,9-15)21-10-19-12-6-18-14-11(13(12)21)3-4-17-14/h3-4,6,10,20H,2,5,7-9H2,1H3,(H,17,18)"	"yes"	""	""
"11682"	"zenuzolac"	""	"Synthetic organic"	""	""	""	""	"442878708"	"10798271"	""	""	"CHEMBL1320667"	""	""	""	""	""	"zenuzolac"	"(S,R)-3-Phenyl-4,5-dihydro-5-isoxazole acetic acid|GIT-027|GIT-27|GIT27|GLS-1027|GLS1027|rac-[(5R)-3-phenyl-4,5-dihydro-1,2-oxazol-5-yl]acetic acid|VGX-1027|VGX1027"	"C1C(ON=C1c1ccccc1)CC(=O)O"	"MUFJHYRCIHHATF-UHFFFAOYSA-N"	"InChI=1S/C11H11NO3/c13-11(14)7-9-6-10(12-15-9)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,13,14)"	"yes"	""	""
"10409"	"zetomipzomib"	""	"Synthetic organic"	""	""	""	""	"385612170"	"117607904"	""	""	"CHEMBL4297468"	""	""	""	""	""	"zetomipzomib"	"compound 12 [PMID: 30380863]|KZR-616|KZR616"	"COc1ccc(cc1)[C@H]([C@@H](C(=O)N[C@H](C(=O)[C@@]1(C)CO1)CC1=CCCC1)NC(=O)[C@@H](NC(=O)CN1CCOCC1)C)O"	"GHYOCDFICYLMRF-UTIIJYGPSA-N"	"InChI=1S/C30H42N4O8/c1-19(31-24(35)17-34-12-14-41-15-13-34)28(38)33-25(26(36)21-8-10-22(40-3)11-9-21)29(39)32-23(16-20-6-4-5-7-20)27(37)30(2)18-42-30/h6,8-11,19,23,25-26,36H,4-5,7,12-18H2,1-3H3,(H,31,35)(H,32,39)(H,33,38)/t19-,23-,25-,26+,30+/m0/s1"	"yes"	""	""
"11257"	"Z-FA-FMK"	""	"Peptide"	""	""	""	""	"434122317"	"6915837"	""	""	"CHEMBL54797"	""	""	""	""	"benzyl N-[(2S)-1-[(4-fluoro-3-oxobutan-2-yl)amino]-1-oxo-3-phenylpropan-2-yl]carbamate"	""	"MDL 201053|MDL-201053|MDL201053|Z-Phe-DL-Ala-fluoromethylketone|ZFA-fmk"	"FCC(=O)C(NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)C"	"ASXVEBPEZMSPHB-PKHIMPSTSA-N"	"InChI=1S/C21H23FN2O4/c1-15(19(25)13-22)23-20(26)18(12-16-8-4-2-5-9-16)24-21(27)28-14-17-10-6-3-7-11-17/h2-11,15,18H,12-14H2,1H3,(H,23,26)(H,24,27)/t15?,18-/m0/s1"	"yes"	""	""
"12101"	"zigakibart"	""	"Antibody"	""	""	""	""	"472319223"	""	""	""	""	""	""	""	""	""	"zigakibart"	"BION-1301|BION1301|clone 14_1G.15"	""	""	""	"yes"	""	""
"5297"	"zileuton"	""	"Synthetic organic"	"yes"	""	""	""	"178101979"	"60490"	""	""	"CHEMBL93"	""	""	""	""	"1-[1-(1-benzothiophen-2-yl)ethyl]-1-hydroxyurea"	"zileuton"	"A-64077|ZYFLO&reg;"	"ON(C(c1cc2c(s1)cccc2)C)C(=O)N"	"MWLSOWXNZPKENC-UHFFFAOYSA-N"	"InChI=1S/C11H12N2O2S/c1-7(13(15)11(12)14)10-6-8-4-2-3-5-9(8)16-10/h2-7,15H,1H3,(H2,12,14)"	"yes"	""	""
"11552"	"ziltivekimab"	""	"Antibody"	""	""	""	""	"441604924"	""	""	""	""	""	""	""	""	""	"ziltivekimab"	"COR-001|COR001|MEDI-5117|MEDI5117|ZILTI"	""	""	""	"yes"	""	""
"10404"	"zilucoplan"	""	"Peptide"	"yes"	""	""	""	"387271627"	"133083018"	""	""	""	""	""	""	""	""	"zilucoplan"	"RA-101495|RA101495|Zilbrysq&reg;"	"CCCCCCCCCCCCCCCC(=O)N[C@H](C(=O)O)CCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NCCCC[C@@H](C(=O)O)NC(=O)[C@H](C1CCCCC1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2c1cccn2)NC(=O)[C@@H](NC(=O)[C@H](C(C)(C)C)NC(=O)[C@@H](N(C(=O)[C@@H]1CC(=O)NCCCC[C@H](NC(=O)C)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)Cc1ccccc1)CCCNC(=N)N)CCC(=O)O)C(C)C)C)CC(=O)O)Cc1ccc(cc1)O)CCC(=O)O)Cc1ccc(cc1)O"	"JDXCOXKBIGBZSK-PSNKNOTQSA-N"	"InChI=1S/C172H278N24O55/c1-9-10-11-12-13-14-15-16-17-18-19-20-27-44-146(202)182-136(170(226)227)53-56-144(200)177-64-67-229-69-71-231-73-75-233-77-79-235-81-83-237-85-87-239-89-91-241-93-95-243-97-99-245-101-103-247-105-107-249-109-111-251-113-112-250-110-108-248-106-104-246-102-100-244-98-96-242-94-92-240-90-88-238-86-84-236-82-80-234-78-76-232-74-72-230-70-68-228-66-59-145(201)175-60-31-29-41-135(169(224)225)186-165(220)152(126-37-25-22-26-38-126)193-162(217)142-43-34-65-196(142)168(223)140(116-125-47-51-129(199)52-48-125)190-157(212)133(54-57-148(204)205)184-161(216)139(117-127-120-180-154-130(127)39-32-62-178-154)188-159(214)138(115-124-45-49-128(198)50-46-124)189-166(221)153(172(5,6)7)194-163(218)143(119-150(208)209)195(8)167(222)141-118-147(203)176-61-30-28-40-131(181-122(4)197)158(213)192-151(121(2)3)164(219)185-134(55-58-149(206)207)156(211)183-132(42-33-63-179-171(173)174)155(210)187-137(160(215)191-141)114-123-35-23-21-24-36-123/h21,23-24,32,35-36,39,45-52,62,120-121,126,131-143,151-153,198-199H,9-20,22,25-31,33-34,37-38,40-44,53-61,63-119H2,1-8H3,(H,175,201)(H,176,203)(H,177,200)(H,178,180)(H,181,197)(H,182,202)(H,183,211)(H,184,216)(H,185,219)(H,186,220)(H,187,210)(H,188,214)(H,189,221)(H,190,212)(H,191,215)(H,192,213)(H,193,217)(H,194,218)(H,204,205)(H,206,207)(H,208,209)(H,224,225)(H,226,227)(H4,173,174,179)/t131-,132-,133-,134-,135-,136-,137-,138-,139-,140-,141-,142-,143-,151-,152-,153+/m0/s1"	"yes"	""	""
"12349"	"zimberelimab"	""	"Antibody"	"yes"	""	""	""	"479821140"	""	""	""	""	""	""	""	""	""	"zimberelimab"	"AB-122|AB122|GLS-010"	""	""	""	"yes"	""	""
"9667"	"zimlovisertib"	""	"Synthetic organic"	""	""	""	""	"348353626"	"118414016"	""	""	""	""	""	""	""	""	"zimlovisertib"	"compound 40 [PMID: 28498658]|PF-06650833|PF06650833"	"CC[C@H]1[C@@H](COc2nccc3c2cc(OC)c(c3)C(=O)N)NC(=O)[C@H]1F"	"JKDGKIBAOAFRPJ-ZBINZKHDSA-N"	"InChI=1S/C18H20FN3O4/c1-3-10-13(22-17(24)15(10)19)8-26-18-11-7-14(25-2)12(16(20)23)6-9(11)4-5-21-18/h4-7,10,13,15H,3,8H2,1-2H3,(H2,20,23)(H,22,24)/t10-,13+,15-/m0/s1"	"yes"	""	""
"9561"	"ziritaxestat"	""	"Synthetic organic"	""	""	""	""	"336446947"	"90420193"	""	""	"CHEMBL3828074"	""	""	""	""	"2-[[2-ethyl-6-[4-[2-(3-hydroxyazetidin-1-yl)-2-oxoethyl]piperazin-1-yl]-8-methylimidazo[1,2-a]pyridin-3-yl]-methylamino]-4-(4-fluorophenyl)-1,3-thiazole-5-carbonitrile"	"ziritaxestat"	"compound 11 [PMID: 28414242]|GLPG-1690|GLPG1690"	"CCc1nc2n(c1N(c1sc(c(n1)c1ccc(cc1)F)C#N)C)cc(cc2C)N1CCN(CC1)CC(=O)N1CC(C1)O"	"REQQVBGILUTQNN-UHFFFAOYSA-N"	"InChI=1S/C30H33FN8O2S/c1-4-24-29(35(3)30-34-27(25(14-32)42-30)20-5-7-21(31)8-6-20)39-15-22(13-19(2)28(39)33-24)37-11-9-36(10-12-37)18-26(41)38-16-23(40)17-38/h5-8,13,15,23,40H,4,9-12,16-18H2,1-3H3"	"yes"	""	""
"813"	"ZK 756326"	""	"Synthetic organic"	""	""	""	""	"135651363"	"11688990"	""	""	"CHEMBL1883966"	""	""	""	""	"2-[2-[4-[[3-(phenoxy)phenyl]methyl]piperazin-1-yl]ethoxy]ethanol"	""	"ZK-756326|ZK756326"	"OCCOCCN1CCN(CC1)Cc1cccc(c1)Oc1ccccc1"	"SHDFUNGIHDOLQM-UHFFFAOYSA-N"	"InChI=1S/C21H28N2O3/c24-14-16-25-15-13-22-9-11-23(12-10-22)18-19-5-4-8-21(17-19)26-20-6-2-1-3-7-20/h1-8,17,24H,9-16,18H2"	"yes"	""	""
"13255"	"ZLN005"	""	"Synthetic organic"	""	""	""	""	"491300037"	"899323"	""	""	"CHEMBL4303368"	""	""	""	""	"2-(4-tert-butylphenyl)-1H-benzimidazole"	""	"ZLN 005|ZLN-005"	"CC(C)(C)C1=CC=C(C=C1)C2=NC3=CC=CC=C3N2"	"LQUNNCQSFFKSSK-UHFFFAOYSA-N"	"InChI=1S/C17H18N2/c1-17(2,3)13-10-8-12(9-11-13)16-18-14-6-4-5-7-15(14)19-16/h4-11H,1-3H3,(H,18,19)"	"yes"	""	""
"11904"	"zomiradomide"	""	"Synthetic organic"	""	""	""	""	"461663459"	"156506667"	""	""	""	""	""	""	""	"N-[2-[4-[[6-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-2-azaspiro[3.3]heptan-2-yl]methyl]cyclohexyl]-5-(2-hydroxypropan-2-yl)-1,3-benzothiazol-6-yl]-6-(trifluoromethyl)pyridine-2-carboxamide"	"zomiradomide"	"compound A [WO2022027058A1]"	"CC(C)(O)c1cc2c(sc(n2)[C@H]2CC[C@H](CN3CC4(CC(CCNc5c6C(=O)N(C7CCC(=O)NC7=O)C(=O)c6ccc5)C4)C3)CC2)cc1NC(=O)c1cccc(n1)C(F)(F)F"	"WDRJGMSUTPVXDH-KBOGUJPVSA-N"	"InChI=1S/C45H48F3N7O6S/c1-43(2,61)28-17-32-34(18-31(28)51-38(57)30-7-4-8-35(50-30)45(46,47)48)62-40(52-32)26-11-9-24(10-12-26)21-54-22-44(23-54)19-25(20-44)15-16-49-29-6-3-5-27-37(29)42(60)55(41(27)59)33-13-14-36(56)53-39(33)58/h3-8,17-18,24-26,33,49,61H,9-16,19-23H2,1-2H3,(H,51,57)(H,53,56,58)/t24-,26-,33?"	"yes"	""	""
"13969"	"ZSA-215"	""	"Synthetic organic"	""	""	""	""	"518520596"	"176365814"	""	""	""	""	""	""	""	"3-[(3-fluoro-5,6-dimethoxy-1-benzoselenophene-2-carbonyl)amino]propanoic acid"	""	"compound 2dr [PMID: 40442142]|ZSA215"	"COC1=C(OC)C=C2C(F)=C([Se]C2=C1)C(=O)NCCC(O)=O"	"VYCPOIAAAQJXPR-UHFFFAOYSA-N"	"InChI=1S/C14H14FNO5Se/c1-20-8-5-7-10(6-9(8)21-2)22-13(12(7)15)14(19)16-4-3-11(17)18/h5-6H,3-4H2,1-2H3,(H,16,19)(H,17,18)"	"yes"	""	""
"14544"	"zumilokibart"	""	"Antibody"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"zumilokibart"	"APG-777|APG777"	""	""	""	"yes"	""	""