penicillamine [Ligand Id: 7264] activity data from GtoPdb and ChEMBL

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ChEMBL ligand: CHEMBL1430 (Cuprimine, D-3-mercaptovaline, Depen, Dimethylcysteine, Distamine, D Mercaptovaline, D Penicillamine, NSC-758421, NSC-81549, Penicillamine, Trolovol)
  • Succinyl-diaminopimelate desuccinylase in Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) [ChEMBL: CHEMBL1075192] [UniProtKB: P44514]
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DB Assay description Assay Type Standard value Standard parameter Original value Original units Original parameter Reference
Succinyl-diaminopimelate desuccinylase in Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (target type: SINGLE PROTEIN) [ChEMBL: CHEMBL1075192] [UniProtKB: P44514]
ChEMBL Inhibition of Haemophilus influenzae recombinant DapE B 4.3 pIC50 50000 nM IC50 Bioorg Med Chem Lett (2009) 19: 6350-6352 [PMID:19822427]

ChEMBL data shown on this page come from version 34:

Zdrazil B, Felix E, Hunter F, Manners EJ, Blackshaw J, Corbett S, de Veij M, Ioannidis H, Lopez DM, Mosquera JF, Magarinos MP, Bosc N, Arcila R, Kizilören T, Gaulton A, Bento AP, Adasme MF, Monecke P, Landrum GA, Leach AR. (2024). The ChEMBL Database in 2023: a drug discovery platform spanning multiple bioactivity data types and time periods. Nucleic Acids Res., 52(D1). DOI: 10.1093/nar/gkad1004. [EPMCID:10767899] [PMID:37933841]
Davies M, Nowotka M, Papadatos G, Dedman N, Gaulton A, Atkinson F, Bellis L, Overington JP. (2015) 'ChEMBL web services: streamlining access to drug discovery data and utilities.' Nucleic Acids Res., 43(W1). DOI: 10.1093/nar/gkv352. [EPMCID:25883136]